論文・総説 - 武部　貴則

分割表示 >> ／  全件表示  133 件中 1 - 133 件目

  1. Sheth M, Sharma M, Lehn M, Reza HAl, Takebe T, Takiar V, Wise-Draper T, Esfandiari L. Three-dimensional matrix stiffness modulates mechanosensitive and phenotypic alterations in oral squamous cell carcinoma spheroids APL Bioengineering. 2024.09; 8 (3): 036106.

  2. Lutolf MP, Radisic M, Beekman J, Huh DD, Huch M, Turco MY, Niloofar Z, Birgani T, Gao D, Yao R, Lin H, Takebe T. In vitro human cell-based models: What can they do and what are their limitations? Cell. 2024.08;

  3. Liu YJ, Kimura M, Li X, Sulc J, Wang Q, López SR, Scantlebery AML, Strotjohann K, Ayala HG, Vijayakumar A, Myers RP, Ivanisevic J, Houtkooper RH, Subramanian GM, Takebe T, Auwerx J. ACMSD inhibition corrects fibrosis, inflammation, and DNA damage in MASLD/MASH Journal of Hepatology. 2024.08;

  4. Quach S, Lewis K, Iwasawa K, Milton Y, Guillot Ahmed YA, Takebe T, Behncke RY, Rezvani M. SAT-180 Targeting neutrophil injury-pathways and fibrogenesis in nonparenchymal immune tissue-like liver organoids generated from human induced pluripotent stem cells Journal of Hepatology. 2024.06; 80 S302-S303.

  5. Toshiya Nishimura, Takanori Takebe. Synthetic human gonadal tissues for toxicology Reproductive Toxicology. 2024.04; 108598.

  6. Masaki Kimura, Takanori Takebe. Cellotype–phenotype associations using ‘organoid villages Trends in Endocrinology & Metabolism. 2024.04; 35 (6): 462-465.

  7. Miao Y, Tan C, Pek NM, Yu Z, Iwasawa K, Kechele DO, Sundaram N, Pastrana-Gomez V, Kishimoto K, Yang M, Jiang C, Tchieu J, Whitsett JA, McCracken KW, Rottier RJ, Kotton DN, Helmrath MA, Wells JM, Takebe T, Zorn AM, Chen Y, Guo M, Gu M. Deciphering Endothelial and Mesenchymal Organ Specification in Vascularized Lung and Intestinal Organoids bioRxiv. 2024.02;

  8. Jurickova I, Dreskin BW, Angerman E, Bonkowski E, Tominaga K, Iwasawa K, Braun T, Takebe T, Helmrath MA, Haberman Y, Wells JM, Denson LA. Eicosatetraynoic Acid Regulates Pro-Fibrotic Pathways in an Induced Pluripotent Stem Cell Derived Macrophage:Human Intestinal Organoid Model of Crohn’s Disease bioRxiv. 2024.01;

  9. Naraoka Y, Mabuchi Y, Kiuchi M, Kumagai K, Hisamatsu D, Yoneyama Y, Takebe T, Akazawa C. Quality Control of Stem Cell-Based Cultured Meat According to Specific Differentiation Abilities Cells. 2024.01; 13 (2): 135.

  10. Sho Osonoi, Takanori Takebe. Organoid-guided precision hepatology for metabolic liver disease Journal of Hepatology. 2024.01; 80 (5): 805-821.

  11. Múnera JO, Kechele DO, Bouffi C, Qu N, Jing R, Maity P, Enriquez JR, Han, Campbell I, Mahe MM, McCauley HA, Zhang X, Sundaram N, Hudson JR, Zarsozo-Lacoste A, Pradhan S, Tominaga K, Sanchez JG, Weiss AAChatuvedi P, Spence JR, Hachimi M, North T, Daley GQ, Mayhew CN, Hu Y, Takebe T, Helmrath MA, Wells JM. Development of functional resident macrophages in human pluripotent stem cell-derived colonic organoids and human fetal colon Cell Stem Cell. 2023.11; 30 (11): 1434-1451.

  12. Reza H, Farooqui Z, Reza A, Conroy C, Iwasawa K, Ogura Y, Okita K, Osafune K, Takebe T. Synthetic augmentation of bilirubin metabolism in human pluripotent stem cell-derived liver organoids Stem Cell Reports. 2023.11; 8 (11):

  13. Kawakami E, Saiki N, Yoneyama Y, Takayama K, Nio Y, Takebe T. Complement factor D targeting protects endotheliopathy in organoid and monkey models of COVID-19 Cell Stem Cell. 2023.10; 30 (10): 1315-1330.

  14. Matsuzaki T, Kawano Y, Horikiri M, Shimokawa Y, Yamazaki T, Okuma N, Koike H, Kimura M, Kawamura R, Yoneyama Y, Furuichi Y, Hakuno F, Takahashi SI, Nakabayashi S, Okamoto S, Nakauchi H, . Preparation of mechanically patterned hydrogels for controlling the self-condensation of cells STAR protocols. 2023.07; 4 (3): 102471.

  15. Tamaoki N, Siebert S, Maeda T, Ha NH, Good ML, Huang Y, Vodnala SK, Haro-Mora JJ, Uchida N, Tisdale JF, Sweeney CL, Choi U, Brault J, Koontz S, Malech HL, Yamazaki Y, Isonaka R, Goldstein DS, Kimura M, Takebe T, Zou J, Stroncek DF, Robey PG, Kruhlak MJ, Restifo NP, Vizcardo R.. Self-organized yolk sac-like organoids allow for scalable generation of multipotent hematopoietic progenitor cells from induced pluripotent stem cells Cell Reports Methods. 2023.04; 3 (4): 100460.

  16. Fujii T, Yoneyama Y, Kinebuchi A, Ozeki N, Maeda S, Saiki N, Fengshi Chen-Yoshikawa T.F., Date H, Nishiwaki K, Takebe T. Enteral liquid ventilation oxygenates a hypoxic pig model iScience. 2023.03; 26 (3):

  17. Kang S, Kimura M, Shrestha S, Lewis P, Lee S, Cai Y, Joshi P, Acharya P, Liu J, Yang Y, Sanchez J, Ayyagari S, Alsberg E, Wells J, Takebe T, Lee M. A Pillar and Perfusion Plate Platform for Robust Human Organoid Culture and Analysis bioRxiv. 2023.03;

  18. Kimura M, Iguchi T, Iwasawa K, Dunn A, Thompson W, Yoneyama Y, Chaturvedi P, Zorn A, Wintzinger M, Quattrocelli M, Watanabe-Chailland M, Zhu G, Fujimoto M, Kumbaji M, Kodaka A, Gindin Y, Chung C, Myers R, Subramanian G, Hwa V, Takebe T. En masse organoid phenotyping informs metabolic-associated genetic susceptibility to NASH Cell. 2022.10; 185 (22): 4216-4232.e16.

  19. Liu Y, Kimura M, Vijayakumar A, Murakami E, Takebe T, Subramanian M, Auwerx J. ENHANCEMENT OF DE NOVO NAD plus BIOSYNTHESIS BY NOVEL ACMSD INHIBITORS IMPROVES MITOCHONDRIAL FUNCTION IN iPSC-DERIVED HUMAN LIVER ORGANOID Hepatology. 2022.10; 76 S706.

  20. Kimura M, Chuang JC, Vijayakumar A, Murakami E, Huss RS, Myers RP, Subramanian, M Takebe T. ENHANCED LIPOGENESIS ASSOCIATED WITH A HIGH-RISK GCKR VARIANT (rs1260326) IS EFFECTIVELY SUPPRESSED BY TLC-2716, A NOVEL, LIVER-TARGETED LXR INVERSE AGONIST IN STEATOTIC HUMAN … HEPATOLOGY. 2022.10; 76 S1280-S1281.

  21. Matsuzaki T, Shimokawa Y, Koike H, Kimura M, Kawano Y, Okuma N, Kawamura R, Yoneyama Y, Furuichi Y, Hakuno F, Takahashi S, Nakabayashi S, Okamoto S, Nakauchi H, Taniguchi H, Takebe T, Yoshikawa H. Mechanical guidance of self-condensation patterns of differentiating progeny iScience. 2022.09; 25 (10): 105109.

  22. Wu Y, Oda M, Hayashi Y, Takebe T, Nagata S, Wang C, Mori K. Blood Vessel Segmentation from Low-Contrast and Wide-Field Optical Microscopic Images of Cranial Window by Attention-Gate-Based Network IEEE. 2022.08; 1864-1873.

  23. Lancaster M, Morris S, Takebe T, Qian L, Gao S, Huch M. Anniversary reflections: Inspiring discoveries and the future of the field Cell Stem Cell. 2022.06; 29 (66): 879-881.

  24. Mituru Mizuno,Takahisa Matsuzaki,Nobutake Ozeki,Hisako Katano,Hideyuki Koga,Takanori Takebe,Hiroshi Yoshikawa,Ichiro Sekiya. Cell membrane fluidity and ROS resistance define DMSO tolerance of cryopreserved synovial MSCs and HUVECs. Stem Cell Research & Therapy. 2022.05; 13 (1): 177. ( PubMed, DOI )

  25. Jurickova I, Bonkowski E, Angerman E, Novak E, Huron A, Akers G, Iwasawa K, Braun T, Hadar R, Hooker M, Han S, Cutler D, Okou D, Kugathasan S, Jegga A, Wells J, Takebe T, Mollen K, Haberman Y, Denson L. Eicosatetraynoic Acid and Butyrate Regulate Human Intestinal Organoid Mitochondrial and Extracellular Matrix Pathways Implicated in Crohn’s Inflammatory Bowel Diseases. 2022.03; 28 (7): 988-1003.

  26. Tominaga K, Kechele D, Sanchez G, McCauley H, Enriquez J, Vales S, Jurickova I, Denson L, Takebe T, Helmrath M, Zorn A, Wells J. GENERATION OF HUMAN INTESTINAL ORGANOIDS CONTAINING TISSUE-RESIDENT IMMUNE CELLS Gastroenterology. 2022.02; 62 (3): S57.

  27. Dunn A, Cai Y, Iwasawa K, Kimura M, Takebe T . Synthesis and application of POLYseq for profiling human liver organoids STAR Protoc. 2021.12; 2 (4): 100976. ( PubMed, DOI )

  28. Reza HA, Ryo O, Takebe T. Organoid Transplant Approaches for the Liver. Transplant international : official journal of the European Society for Organ Transplantation. 2021.10; ( PubMed, DOI )

  29. Naraoka Y, Mabuchi Y, Yoneyama Y, Suto EG, Hisamatsu D, Ikeda M, Ito R, Nakamura T, Takebe T, Akazawa C. Isolation and Characterization of Tissue Resident CD29-Positive Progenitor Cells in Livestock to Generate a Three-Dimensional Meat Bud. Cells. 2021.09; 10 (9): ( PubMed, DOI )

  30. Dunn A, Cai Y, Iwasawa K, Kimura M, Takebe T. POLYseq: A poly(β-amino ester)-based vector for multifunctional cellular barcoding. Stem cell reports. 2021.09; 16 (9): 2149-2158. ( PubMed, DOI )

  31. Iwasawa K, Takebe T. Organogenesis in vitro. Current opinion in cell biology. 2021.08; 73 84-91. ( PubMed, DOI )

  32. Marsee A, Roos FJM, Verstegen MMA, HPB Organoid Consortium., Gehart H, de Koning E, Lemaigre F, Forbes SJ, Peng WC, Huch M, Takebe T, Vallier L, Clevers H, van der Laan LJW, Spee B. Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids. Cell stem cell. 2021.05; 28 (5): 816-832. ( PubMed, DOI )

  33. Okabe R, Chen-Yoshikawa TF, Yoneyama Y, Kobayashi E, Date H, Takebe T. Mammalian enteral ventilation ameliorates respiratory failure Med. 2021.05; 2 (6): 773-783 . ( DOI )

  34. Annabi N, Baker M, Boettiger A, Chakraborty D, Chen Y, Corbett KS, Correia B, Dahlman J, de Oliveira T, Ertuerk A, Yanik MF, Henaff E, Huch M, Iliev ID, Jacobs T, Junca H, Keung A, Kolodkin-Gal I, Krishnaswamy S, Lancaster M, Macosko E, Martínez-Núñez MA, Miura K, Molloy J, Cruz AO, Platt RJ, Posey AD Jr, Shao H, Simunovic M, Slavov N, Takebe T, Vandenberghe LH, Varshney RK, Wang J. Voices of biotech research. Nature biotechnology. 2021.03; 39 (3): 281-286. ( PubMed, DOI )

  35. Dobrindt K, Hoagland DA, Seah C, Kassim B, O'Shea CP, Murphy A, Iskhakova M, Fernando MB, Powell SK, Deans PJM, Javidfar B, Peter C, Møller R, Uhl SA, Garcia MF, Kimura M, Iwasawa K, Crary JF, Kotton DN, Takebe T, Huckins LM, tenOever BR, Akbarian S, Brennand KJ. Common Genetic Variation in Humans Impacts In Vitro Susceptibility to SARS-CoV-2 Infection. Stem cell reports. 2021.03; 16 (3): 505-518. ( PubMed, DOI )

  36. Koike H, Iwasawa K, Ouchi R, Maezawa M, Kimura M, Kodaka A, Nishii S, Thompson WL, Takebe T. Engineering human hepato-biliary-pancreatic organoids from pluripotent stem cells. Nature protocols. 2021.02; 16 (2): 919-936. ( PubMed, DOI )

  37. Lewis K, Yoshimoto M, Takebe T. Fetal liver hematopoiesis: from development to delivery. Stem cell research & therapy. 2021.02; 12 (1): 139. ( PubMed, DOI )

  38. Thompson WL, Takebe T. Human liver model systems in a dish. Development, growth & differentiation. 2021.01; ( PubMed, DOI )

  39. Funata M, Nio Y, Erion DM, Thompson WL, Takebe T. The promise of human organoids in the digestive system. Cell death and differentiation. 2021.01; 28 (1): 84-94. ( PubMed, DOI )

  40. Fang H, Geng S, Hao M, Chen Q, Liu M, Liu C, Tian Z, Wang C, Takebe T, Guan JL, Chen Y, Guo Z, He W, Diao J. Simultaneous Zn<sup>2+</sup> tracking in multiple organelles using super-resolution morphology-correlated organelle identification in living cells. Nature communications. 2021.01; 12 (1): 109. ( PubMed, DOI )

  41. Tamaoki N, Siebert S, Maeda T, Ngoc-H Ha, Good M L, Huang Y, Vodnala S K, Haro-Mora J J, Uchida N, Tisdale J F, Sweeney C L, Choi U, Brault J, Koontz S, Malech H L, Yamazaki Y, Isonaka R, Goldstein . Self-organized yolk sac-like organoids allow for scalable generation of multipotent hematopoietic progenitor cells from human induced pluripotent stem cells bioRxiv. 2021.01; 3 (4): 100460.

  42. Hayashi H, Osaka S, Sakabe K, Fukami A, Kishimoto E, Aihara E, Sabu Y, Mizutani A, Kusuhara H, Naritaka N, Zhang W, Huppert SS, Sakabe M, Nakamura T, Hu YC, Mayhew C, Setchell K, Takebe T, Asai A. Modeling Human Bile Acid Transport and Synthesis in Stem Cell-Derived Hepatocytes with a Patient-Specific Mutation. Stem cell reports. 2020.12; ( PubMed, DOI )

  43. Sekine K, Ogawa S, Tsuzuki S, Kobayashi T, Ikeda K, Nakanishi N, Takeuchi K, Kanai E, Otake Y, Okamoto S, Kobayashi T, Takebe T, Taniguchi H. Generation of human induced pluripotent stem cell-derived liver buds with chemically defined and animal origin-free media. Scientific reports. 2020.10; 10 (1): 17937. ( PubMed, DOI )

  44. Koido M, Kawakami E, Fukumura J, Noguchi Y, Ohori M, Nio Y, Nicoletti P, Aithal GP, Daly AK, Watkins PB, Anayama H, Dragan Y, Shinozawa T, Takebe T. Polygenic architecture informs potential vulnerability to drug-induced liver injury. Nature medicine. 2020.10; 26 (10): 1541-1548. ( PubMed, DOI )

  45. Shinozawa T, Kimura M, Cai Y, Saiki N, Yoneyama Y, Ouchi R, Koike H, Maezawa M, Zhang RR, Dunn A, Ferguson A, Togo S, Lewis K, Thompson W, Asai A, Takebe T. High-Fidelity Drug-Induced Liver Injury Screen Using Human Pluripotent Stem Cell-Derived Organoids. Gastroenterology. 2020.10; ( PubMed, DOI )

  46. Okabe R, Chen-Yoshikawa TF, Yoshizawa A, Hirashima T, Saito M, Date H, Takebe T. Orthotopic foetal lung tissue direct injection into lung showed a preventive effect against paraquat-induced acute lung injury in mice. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery. 2020.09; 58 (3): 638-645. ( PubMed, DOI )

  47. Kobayashi Naritaka, Togo Shodai, Matsuzaki Takahisa, Hashiseko Kaede, Kawamura Ryuzo, Suganuma Masami, Nakabayashi Seiichiro, Yoneyama Yosuke, Ouchi Rie, Takebe Takanori, Yoshikawa Hiroshi Y.. Stiffness distribution analysis in indentation depth direction reveals clear mechanical features of cells and organoids by using AFM APPLIED PHYSICS EXPRESS. 2020.09; 13 (9):

  48. Han L, Chaturvedi P, Kishimoto K, Koike H, Nasr T, Iwasawa K, Giesbrecht K, Witcher PC, Eicher A, Haines L, Lee Y, Shannon JM, Morimoto M, Wells JM, Takebe T, Zorn AM. Single cell transcriptomics identifies a signaling network coordinating endoderm and mesoderm diversification during foregut organogenesis. Nature communications. 2020.08; 11 (1): 4158. ( PubMed, DOI )

  49. Nio, Y; Ohori, M; Kawakami, E; Shinozawa, T; Saiki, N; Takebe, T. Drug screening against complement disorders using human stem cell-derived endothelium and liver organoids JOURNAL OF HEPATOLOGY. 2020.08; 73 S568-S569.

  50. Sakabe K, Takebe T, Asai A. Organoid Medicine in Hepatology. Clinical liver disease. 2020.01; 15 (1): 3-8. ( PubMed, DOI )

  51. Thompson WL, Takebe T. Generation of multi-cellular human liver organoids from pluripotent stem cells. Methods in cell biology. 2020; 159 47-68. ( PubMed, DOI )

  52. Iizuka, S; Nishii, S; Tanimoto, E; Nakazawa, H; Kodaka, A; Takebe, T. Waiting Time Analysis at University Hospitals Based on Visitor Psychology HUMAN INTERFACE AND THE MANAGEMENT OF INFORMATION. DESIGNING INFORMATION, HIMI 2020, PT I. 2020; 12184 212-221. ( DOI )

  53. Fang H, Yao S, Chen Q, Liu C, Cai Y, Geng S, Bai Y, Tian Z, Zacharias AL, Takebe T, Chen Y, Guo Z, He W, Diao J. De Novo-Designed Near-Infrared Nanoaggregates for Super-Resolution Monitoring of Lysosomes in Cells, in Whole Organoids, and in Vivo. ACS nano. 2019.12; 13 (12): 14426-14436. ( PubMed, DOI )

  54. Liu T, Zhou L, Yang K, Iwasawa K, Kadekaro AL, Takebe T, Andl T, Zhang Y. The β-catenin/YAP signaling axis is a key regulator of melanoma-associated fibroblasts. Signal transduction and targeted therapy. 2019.12; 4 63. ( PubMed, DOI )

  55. Koike H, Iwasawa K, Ouchi R, Maezawa M, Giesbrecht K, Saiki N, Ferguson A, Kimura M, Thompson WL, Wells JM, Zorn AM, Takebe T. Modelling human hepato-biliary-pancreatic organogenesis from the foregut-midgut boundary. Nature. 2019.10; 574 (7776): 112-116. ( PubMed, DOI )

  56. Takebe T. Creativity for a cure. Nature medicine. 2019.06; 25 (6): 868. ( PubMed, DOI )

  57. Takebe T, Wells JM. Organoids by design. Science (New York, N.Y.). 2019.06; 364 (6444): 956-959. ( PubMed, DOI )

  58. Ouchi R, Togo S, Kimura M, Shinozawa T, Koido M, Koike H, Thompson W, Karns RA, Mayhew CN, McGrath PS, McCauley HA, Zhang RR, Lewis K, Hakozaki S, Ferguson A, Saiki N, Yoneyama Y, Takeuchi I, Mabuchi Y, Akazawa C, Yoshikawa HY, Wells JM, Takebe T. Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids. Cell metabolism. 2019.05; ( PubMed, DOI )

  59. Okabe R., Chen-Yoshikawa T., Yoshizawa A., Hirashima T., Gochi F., Yamagishi H., Takahagi A., Saito M., Ohsumi A., Nakajima D., Hamaji M., Date H., Takebe T.. Orthotopic Implantation with Immature Mouse Fetal Lung Did Not Self-Organize Airways Structures, but Improved Prognosis of Mice with Paraquat-Induced Severe Lung Injury JOURNAL OF HEART AND LUNG TRANSPLANTATION. 2019.04; 38 (4): S257.

  60. Iizuka, S; Takebe, T; Nishii, S; Kodaka, A. Approach for Communication Design for Motivation to Health Behavior HUMAN INTERFACE AND THE MANAGEMENT OF INFORMATION. VISUAL INFORMATION AND KNOWLEDGE MANAGEMENT, HIMI 2019, PT I. 2019; 11569 425-436. ( DOI )

  61. Asai Akihiro, Hayashi Hisamitsu, Ibrahim Leena, Ssakabe Kokoro, Brandser Nicholas Ryan, Ishii Ken, Takebe Takanori, Aihara Eitaro. Truncating Mutation of Bsep/ABCB11 in Human Hepatocytes Derived from Induced Pluripotent Stem Cells Increases Their Susceptibility to Bile Acid Injury HEPATOLOGY. 2018.10; 68 83A-84A.

  62. Ayabe H, Anada T, Kamoya T, Sato T, Kimura M, Yoshizawa E, Kikuchi S, Ueno Y, Sekine K, Camp JG, Treutlein B, Ferguson A, Suzuki O, Takebe T, Taniguchi H. Optimal Hypoxia Regulates Human iPSC-Derived Liver Bud Differentiation through Intercellular TGFB Signaling. STEM CELL REPORTS. 2018.08; 11 (2): 306-316. ( PubMed, DOI )

  63. Nie YZ, Zheng YW, Miyakawa K, Murata S, Zhang RR, Sekine K, Ueno Y, Takebe T, Wakita T, Ryo A, Taniguchi H. Recapitulation of hepatitis B virus-host interactions in liver organoids from human induced pluripotent stem cells. EBioMedicine. 2018.08; ( PubMed, DOI )

  64. Matsuzaki T, Matsumoto S, Kasai T, Yoshizawa E, Okamoto S, Yoshikawa HY, Taniguchi H, Takebe T. Defining Lineage-Specific Membrane Fluidity Signatures that Regulate Adhesion Kinetics. Stem Cell Reports. 2018.08; 11 (4): 852-860. ( DOI )

  65. Kimura, M., Azuma, M., Zhang, R. -R., Thompson, W., Mayhew, C. N., & Takebe, T.. Digitalized Human Organoid for Wireless Phenotyping. iScience. 2018.07; 4 294-301. ( DOI )

  66. Rao Mahendra S., Pei Ying, Garcia Thelma Y., Chew Shereen, Kasai Toshiharu, Hisai Tomoko, Taniguchi Hideki, Takebe Takanori, Lamba Deepak A., Zeng Xianmin. Illustrating the potency of current Good Manufacturing Practice-compliant induced pluripotent stem cell lines as a source of multiple cell lineages using standardized protocols CYTOTHERAPY. 2018.06; 20 (6): 861-872. ( PubMed, DOI )

  67. Takebe Takanori, Wells James M., Helmrath Michael A., Zorn Aaron M.. Organoid Center Strategies for Accelerating Clinical Translation CELL STEM CELL. 2018.06; 22 (6): 806-809. ( PubMed, DOI )

  68. Takahashi Y, Takebe T, Taniguchi H. Methods for Generating Vascularized Islet-Like Organoids Via Self-Condensation. Current protocols in stem cell biology. 2018.05; 45 (1): e49. ( PubMed, DOI )

  69. Takahashi Yoshinobu, Sekine Keisuke, Kin Tatsuya, Takebe Takanori, Taniguchi Hideki. Self-Condensation Culture Enables Vascularization of Tissue Fragments for Efficient Therapeutic Transplantation CELL REPORTS. 2018.05; 23 (6): 1620-1629. ( PubMed, DOI )

  70. Zhang Ran-Ran, Koido Masaru, Tadokoro Tomomi, Ouchi Rie, Matsuno Tatsuya, Ueno Yasuharu, Sekine Keisuke, Takebe Takanori, Taniguchi Hideki. Human iPSC-Derived Posterior Gut Progenitors Are Expandable and Capable of Forming Gut and Liver Organoids STEM CELL REPORTS. 2018.03; 10 (3): 780-793. ( PubMed, DOI )

  71. Lewis K, Takebe T. Tumoroid à la carte: Path for personalization. Hepatology (Baltimore, Md.). 2018.02; ( PubMed, DOI )

  72. Takebe Takanori, Sekine Keisuke, Kimura Masaki, Yoshizawa Emi, Ayano Satoru, Koido Masaru, Funayama Shizuka, Nakanishi Noriko, Hisai Tomoko, Kobayashi Tatsuya, Kasai Toshiharu, Kitada Rina, Mori Akira, Ayabe Hiroaki, Ejiri Yoko, Amimoto Naoki, Yamazaki Yosuke, Ogawa Shimpei, Ishikawa Momotaro, Kiyota Yasujiro, Sato Yasuhiko, Nozawa Kohei, Okamoto Satoshi, Ueno Yasuharu, Taniguchi Hideki. Massive and Reproducible Production of Liver Buds Entirely from Human Pluripotent Stem Cells CELL REPORTS. 2017.12; 21 (10): 2661-2670. ( PubMed, DOI )

  73. Takebe Takanori, Zhang Boyang, Radisic Milica. Synergistic Engineering: Organoids Meet Organs-on-a-Chip CELL STEM CELL. 2017.09; 21 (3): 297-300. ( PubMed, DOI )

  74. Takebe Takanori, Sekine Keisuke, Camp Gray, Treutlein Barbara. Human Liver Bud Organoid Models Development CELL SYSTEMS. 2017.07; 5 (1): 2.

  75. Camp J. Gray, Sekine Keisuke, Gerber Tobias, Loeffler-Wirth Henry, Binder Hans, Gac Malgorzata, Kanton Sabina, Kageyama Jorge, Damm Georg, Seehofer Daniel, Belicova Lenka, Bickle Marc, Barsacchi Rico, Okuda Ryo, Yoshizawa Emi, Kimura Masaki, Ayabe Hiroaki, Taniguchi Hideki, Takebe Takanori, Treutlein Barbara. Multilineage communication regulates human liver bud development from pluripotency NATURE. 2017.06; 546 (7659): 533-+. ( PubMed, DOI )

  76. Lee S., Takahashi Y., Lee K. M., Mizuno M., Nemeno J. G., Takebe T., Lee J. I.. Viability and Functional Assessment of Murine Pancreatic Islets After Transportation Between Korea and Japan (vol 47, pg 738, 2015) TRANSPLANTATION PROCEEDINGS. 2017.04; 49 (3): 616.

  77. Koike Hiroyuki, Zhang Ran-Ran, Ueno Yasuharu, Sekine Keisuke, Zheng Yun-Wen, Takebe Takanori, Taniguchi Hideki. Nutritional modulation of mouse and human liver bud growth through a branched-chain amino acid metabolism DEVELOPMENT. 2017.03; 144 (6): 1018-1024. ( PubMed, DOI )

  78. Sekine K, Takebe T, Taniguch H. Liver Regeneration Using Cultured Liver Bud. Methods Mol Biol. . 2017.03; ( PubMed, DOI )

  79. Asai Akihiro, Aihara Eitaro, Watson Carey, Mourya Reena, Mizuochi Tatsuki, Shivakumar Pranavkumar, Phelan Kieran, Mayhew Christopher, Helmrath Michael, Takebe Takanori, Wells James, Bezerra Jorge A.. Paracrine signals regulate human liver organoid maturation from induced pluripotent stem cells DEVELOPMENT. 2017.03; 144 (6): 1056-1064. ( PubMed, DOI )

  80. Shinozawa Tadahiro, Yoshikawa Hiroshi Y., Takebe Takanori. Reverse engineering liver buds through self-driven condensation and organization towards medical application DEVELOPMENTAL BIOLOGY. 2016.12; 420 (2): 221-229. ( PubMed, DOI )

  81. Ito Keitaro, Sakuma Shinya, Kimura Masaki, Takebe Takanori, Kaneko Makoto, Arai Fumihito. Temporal Transition of Mechanical Characteristics of HUVEC/MSC Spheroids Using a Microfluidic Chip with Force Sensor Probes MICROMACHINES. 2016.12; 7 (12): ( DOI )

  82. Koike, H., & Takebe, T.. Generating Mini-Organs in Culture. Current Pathobiology Reports. 2016.06; 4 (2): 59-68. ( DOI )

  83. Takahashi Yoshinobu, Takebe Takanori, Taniguchi Hideki. Engineering pancreatic tissues from stem cells towards therapy REGENERATIVE THERAPY. 2016.03; 3 15-23. ( DOI )

  84. Ito, K., Sakuma, S., Kimura, M., Takebe, T., Kaneko, M., & Arai, F. . STIFFNESS-INDEX MAP BASED ON SINGLE CELL-SPHEROID ANALYSIS USING ROBOT INTEGRATED MICROFLUIDIC CHIIP. CELL TRANSPLANTATION. 2016.01; 25 (5): 951-962. ( DOI )

  85. Asai Akihiro, Aihara Eitaro, Mizuochi Tatsuki, Phelan Kieran, Mayhew Christopher, Shivakumar Pranavkumar, Takebe Takanori, Wells James, Bezerra Jorge A.. Hepatic maturation of induced Pluripotent Stem Cells is regulated by paracrine signals from endothelial and mesenchymal stem cells in culture and during organoid formation HEPATOLOGY. 2015.10; 62 544A.

  86. Takebe Takanori, Enomura Masahiro, Yoshizawa Emi, Kimura Masaki, Koike Hiroyuki, Ueno Yasuharu, Matsuzaki Takahisa, Yamazaki Takashi, Toyohara Takafumi, Osafune Kenji, Nakauchi Hiromitsu, Yoshikawa Hiroshi Y., Taniguchi Hideki. Vascularized and Complex Organ Buds from Diverse Tissues via Mesenchymal Cell-Driven Condensation CELL STEM CELL. 2015.05; 16 (5): 556-565. ( PubMed, DOI )

  87. Lee S., Takahashi Y., Lee K. M., Mizuno M., Nemeno J. G., Takebe T., Lee J. I.. Viability and Functional Assessment of Murine Pancreatic Islets After Transportation Between Korea and Japan TRANSPLANTATION PROCEEDINGS. 2015.04; 47 (3): 738-741. ( DOI )

  88. Rashid Tamir, Takebe Takanori, Nakauchi Hiromitsu. Novel strategies for liver therapy using stem cells GUT. 2015.01; 64 (1): 1-4. ( PubMed, DOI )

  89. Zhang, R. R., Koike, H., & Takebe, T.. The visualization of human organogenesis from stem cells by recapitulating multicellular interactions. Hyper Bio Assembler for 3D Cellular Systems. 2015.01; 275-283. ( DOI )

  90. TANIGUCHI, H., & TAKEBE, T.. Generation of functional human organs from pluripotent stem cells. Japanese Journal of Transplantation. 2015.01; 50 (1): 24-30.

  91. Kawabata Y., Nishihara G. N., Yamaguchi T., Takebe T., Teruya K., Sato T., Soyano K.. The effect of spine postures on the hydrodynamic drag in Epinephelus ongus larvae JOURNAL OF FISH BIOLOGY. 2014.11; 85 (5): 1757-1765. ( DOI )

  92. Takebe Takanori, Kobayashi Shinji, Suzuki Hiromu, Mizuno Mitsuru, Chang Yu-Min, Yoshizawa Emi, Kimura Masaki, Hori Ayaka, Asano Jun, Maegawa Jiro, Taniguchi Hideki. Transient vascularization of transplanted human adult-derived progenitors promotes self-organizing cartilage JOURNAL OF CLINICAL INVESTIGATION. 2014.10; 124 (10): 4325-4334. ( PubMed, DOI )

  93. Takebe T., Taniguchi H.. Human iPSC-Derived Miniature Organs: A Tool for Drug Studies CLINICAL PHARMACOLOGY & THERAPEUTICS. 2014.09; 96 (3): 310-313. ( DOI )

  94. Zheng Yun-Wen, Tsuchida Tomonori, Shimao Taiki, Li Bin, Takebe Takanori, Zhang Ran-Ran, Sakurai Yu, Ueno Yasuharu, Sekine Keisuke, Ishibashi Naoto, Imajima Makiko, Tanaka Takuji, Taniguchi Hideki. The CD133(+)CD44(+) Precancerous Subpopulation of Oval Cells Is a Therapeutic Target for Hepatocellular Carcinoma STEM CELLS AND DEVELOPMENT. 2014.09; 23 (18): 2237-2249. ( PubMed, DOI )

  95. Koike Hiroyuki, Ouchi Rie, Ueno Yasuharu, Nakata Susumu, Obana Yuta, Sekine Keisuke, Zheng Yun-Wen, Takebe Takanori, Isono Kyoichi, Koseki Haruhiko, Taniguchi Hideki. Polycomb Group Protein Ezh2 Regulates Hepatic Progenitor Cell Proliferation and Differentiation in Murine Embryonic Liver PLOS ONE. 2014.08; 9 (8): e104776. ( PubMed, DOI )

  96. Takebe, T., Yoshikawa, H., & Taniguchi, H. . 2S-Ep04 Vascularized and functional organ from pluripotent stem cells. 日本生物工学会大会講演要旨集. 2014.08; 66-105.

  97. Osaki, T., Takebe, T., & Fukuda, J. . 2P-182 Engineering vascularized liver-like tissues with iPS-derived hepatic endoderm spheroids. 日本生物工学会大会講演要旨集. 2014.08; 66-152.

  98. Koike Hiroyuki, Ueno Yasuharu, Naito Takako, Shiina Tomoya, Nakata Susumu, Ouchi Rie, Obana Yuta, Sekine Keisuke, Zheng Yun-Wen, Takebe Takanori, Isono Kyo-ichi, Koseki Haruhiko, Taniguchi Hideki. Ring1B Promotes Hepatic Stem/Progenitor Cell Expansion Through Simultaneous Suppression of Cdkn1a and Cdkn2a in Mice HEPATOLOGY. 2014.07; 60 (1): 323-333. ( PubMed, DOI )

  99. Jo Y. H., Jang I. J., Nemeno J. G., Lee S., Kim B. Y., Nam B. M., Yang W., Lee K. M., Kim H., Takebe T., Kim Y. S., Lee J. I.. Artificial Islets From Hybrid Spheroids of Three Pancreatic Cell Lines TRANSPLANTATION PROCEEDINGS. 2014.05; 46 (4): 1156-1160. ( DOI )

  100. Tsuchida T., Zheng Y. -W., Zhang R. -R., Takebe T., Ueno Y., Sekine K., Taniguchi H.. The Development of Humanized Liver With Rag1 Knockout Rats TRANSPLANTATION PROCEEDINGS. 2014.05; 46 (4): 1191-1193. ( DOI )

  101. Enomoto Y., Enomura M., Takebe T., Mitsuhashi Y., Kimura M., Yoshizawa E., Taniguchi H.. Self-Formation of Vascularized Hepatic Tissue From Human Adult Hepatocyte TRANSPLANTATION PROCEEDINGS. 2014.05; 46 (4): 1243-1246. ( DOI )

  102. Zhang R., Takebe T., Sekine K., Koike H., Zheng Y., Taniguchi H.. Identification of Proliferating Human Hepatic Cells From Human Induced Pluripotent Stem Cells TRANSPLANTATION PROCEEDINGS. 2014.05; 46 (4): 1201-1204. ( DOI )

  103. Takahashi Y., Takebe T., Enomura M., Koike N., Lee S., Nemeno J. G., Sekine K., Lee J. I., Taniguchi H.. High-Resolution Intravital Imaging for Monitoring the Transplanted Islets in Mice TRANSPLANTATION PROCEEDINGS. 2014.05; 46 (4): 1166-1168. ( DOI )

  104. Sekine K., Takebe T., Taniguchi H.. Fluorescent Labeling and Visualization of Human Induced Pluripotent Stem Cells With the Use of Transcription Activator-like Effector Nucleases TRANSPLANTATION PROCEEDINGS. 2014.05; 46 (4): 1205-1207. ( DOI )

  105. Zheng Y. -W., Nie Y. -Z., Tsuchida T., Zhang R. -R., Aoki K., Sekine K., Ogawa M., Takebe T., Ueno Y., Sakakibara H., Hirahara F., Taniguchi H.. Evidence of a Sophisticatedly Heterogeneous Population of Human Umbilical Vein Endothelial Cells TRANSPLANTATION PROCEEDINGS. 2014.05; 46 (4): 1251-1253. ( DOI )

  106. Mizuno M., Takebe T., Kobayashi S., Kinnura S., Masutani M., Lee S., Jo Y. H., Lee Ji, Taniguchi H.. Elastic Cartilage Reconstruction by Transplantation of Cultured Hyaline Cartilage-Derived Chondrocytes TRANSPLANTATION PROCEEDINGS. 2014.05; 46 (4): 1217-1221. ( DOI )

  107. Yang W., Lee S., Jo Y. H., Lee K. M., Nemeno J. G., Nam B. M., Kim B. Y., Jang I. J., Kim H. N., Takebe T., Lee J. I.. Effects of Natural Cartilaginous Extracellular Matrix on Chondrogenic Potential for Cartilage Cell Transplantation TRANSPLANTATION PROCEEDINGS. 2014.05; 46 (4): 1247-1250. ( DOI )

  108. Kim B. Y., Nam B. M., Lee K. M., Jo Y. H., Nemeno J. G., Yang W., Lee S., Kim H., Jang I. J., Takebe T., Lee J. I.. Effect of Preservation Conditions on Cartilage Tissue for Cell Transplantation TRANSPLANTATION PROCEEDINGS. 2014.05; 46 (4): 1139-1144. ( DOI )

  109. Nam B. M., Kim B. Y., Jo Y. H., Lee S., Nemeno J. G., Yang W., Lee K. M., Kim H., Jang I. J., Takebe T., Lee J. I.. Effect of Cryopreservation and Cell Passage Number on Cell Preparations Destined for Autologous Chondrocyte Transplantation TRANSPLANTATION PROCEEDINGS. 2014.05; 46 (4): 1145-1149. ( DOI )

  110. Okuda R, Sekine K, Hisamatsu D, Ueno Y, Takebe T, Zheng YW, Taniguchi H. Tropism of cancer stem cells to a specific distant organ. In vivo (Athens, Greece). 2014.05; 28 (3): 361-5. ( PubMed )

  111. Takebe, T., Koike, N., Sekine, K., Fujiwara, R., Amiya, T., Zheng, Y. -W., & Taniguchi, H. . Engineering of human hepatic tissue with functional vascular networks. ORGANOGENESIS. 2014.04; 10 (2): 260-267. ( DOI )

  112. Mizuno Mitsuru, Kobayashi Shinji, Takebe Takanori, Kan Hiroomi, Yabuki Yuichiro, Matsuzaki Takahisa, Yoshikawa Hiroshi Y., Nakabayashi Seiichiro, Ik Lee Jeong, Maegawa Jiro, Taniguchi Hideki. Brief Report: Reconstruction of Joint Hyaline Cartilage by Autologous Progenitor Cells Derived from Ear Elastic Cartilage STEM CELLS. 2014.03; 32 (3): 816-821. ( PubMed, DOI )

  113. Takebe Takanori, Zhang Ran-Ran, Koike Hiroyuki, Kimura Masaki, Yoshizawa Emi, Enomura Masahiro, Koike Naoto, Sekine Keisuke, Taniguchi Hideki. Generation of a vascularized and functional human liver from an iPSC-derived organ bud transplant NATURE PROTOCOLS. 2014.02; 9 (2): 396-409. ( PubMed, DOI )

  114. Takebe, T., & Taniguchi, H. . Vascularized and functional liver devided from human induced pluripotent stem cells by recapitulating organogenesis. Yokohama Medical Journal. 2014.01; 65 (4): 503-507.

  115. Ohgane, H., Takebe, T., Sekine, K., & Taniguchi, H.. Efficient generation of mature hepatocyte-like cells from human iPSCs. 2014.01;

  116. Zhang, R. -R., Takebe, T., Miyazaki, L., Takayama, M., Koike, H., Kimura, M., . . . Taniguchi, H.. Efficient hepatic differentiation of human induced pluripotent stem cells in a three-dimensional microscale culture. Methods Mol Biol. 2014.01; 1210 131-141. ( DOI )

  117. Tanaka Hiroyasu, Tanaka Shin, Sekine Keisuke, Kita Sayaka, Okamura Ai, Takebe Takanori, Zheng Yun-Wen, Ueno Yasuharu, Tanaka Junzo, Taniguchi Hideki. The generation of pancreatic beta-cell spheroids in a simulated microgravity culture system BIOMATERIALS. 2013.07; 34 (23): 5785-5791. ( PubMed, DOI )

  118. Takebe Takanori, Sekine Keisuke, Enomura Masahiro, Koike Hiroyuki, Kimura Masaki, Ogaeri Takunori, Zhang Ran-Ran, Ueno Yasuharu, Zheng Yun-Wen, Koike Naoto, Aoyama Shinsuke, Adachi Yasuhisa, Taniguchi Hideki. Vascularized and functional human liver from an iPSC-derived organ bud transplant NATURE. 2013.07; 499 (7459): 481-+. ( PubMed, DOI )

  119. Koike Hiroyuki, Kubota Koji, Sekine Keisuke, Takebe Takanori, Ouchi Rie, Zheng Yun-Wen, Ueno Yasuharu, Tanigawa Naoki, Taniguchi Hideki. Establishment of automated culture system for murine induced pluripotent stem cells BMC BIOTECHNOLOGY. 2012.11; 12 81. ( PubMed, DOI )

  120. Takasaki K., Takebe T.. An h-dependent formulation of the Kadomtsev-Petviashvili hierarchy THEORETICAL AND MATHEMATICAL PHYSICS. 2012.05; 171 (2): 683-690. ( DOI )

  121. Takebe T., Sekine K., Suzuki Y., Enomura M., Tanaka S., Ueno Y., Zheng Y. -W., Taniguchi H.. Self-Organization of Human Hepatic Organoid by Recapitulating Organogenesis In Vitro TRANSPLANTATION PROCEEDINGS. 2012.05; 44 (4): 1018-1020. ( DOI )

  122. Sekine K., Takebe T., Enomura M., Matsui C., Tanaka H., Taniguchi H.. Regenerative Medicine Approach as an Alternative Treatment to Islet Transplantation TRANSPLANTATION PROCEEDINGS. 2012.05; 44 (4): 1104-1106. ( DOI )

  123. Takebe T., Kobayashi S., Kan H., Suzuki H., Yabuki Y., Mizuno M., Adegawa T., Yoshioka T., Tanaka J., Maegawa J., Taniguchi H.. Human Elastic Cartilage Engineering from Cartilage Progenitor Cells Using Rotating Wall Vessel Bioreactor TRANSPLANTATION PROCEEDINGS. 2012.05; 44 (4): 1158-1161. ( DOI )

  124. Sekine K., Takebe T., Suzuki Y., Kamiya A., Nakauchi H., Taniguchi H.. Highly Efficient Generation of Definitive Endoderm Lineage from Human Induced Pluripotent Stem Cells TRANSPLANTATION PROCEEDINGS. 2012.05; 44 (4): 1127-1129. ( DOI )

  125. Takebe T., Koike N., Sekine K., Enomura M., Chiba Y., Ueno Y., Zheng Y. -W., Taniguchi H.. Generation of Functional Human Vascular Network TRANSPLANTATION PROCEEDINGS. 2012.05; 44 (4): 1130-1133. ( DOI )

  126. Kobayashi Shinji, Takebe Takanori, Zheng Yun-Wen, Mizuno Mitsuru, Yabuki Yuichiro, Maegawa Jiro, Taniguchi Hideki. Presence of Cartilage Stem/Progenitor Cells in Adult Mice Auricular Perichondrium PLOS ONE. 2011.10; 6 (10): e26393. ( PubMed, DOI )

  127. Kobayashi Shinji, Takebe Takanori, Inui Midori, Iwai Sayaka, Kan Hiroomi, Zheng Yun-Wen, Maegawa Jiro, Taniguchi Hideki. Reconstruction of human elastic cartilage by a CD44(+) CD90(+) stem cell in the ear perichondrium PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2011.08; 108 (35): 14479-14484. ( PubMed, DOI )

  128. 平井亜整、武部貴則. 脂肪性肝疾患を模倣する幹細胞・オルガノイド研究の最前線 臨床免疫・アレルギー科. 2024.05; 81 (5): 417-424.

  129. 藤井祐、武部貴則. 医療資源の枯渇に備える研究：腸換気 麻酔. 2024.03; 73 (3): 185-192.

  130. Ohori Momoko, Saiki Norikazu, Yashiro Hiroaki, Funata Masaki, Kono Tamaki, Ogawa Shinji, Nio Yasunori, Takebe Takanori. MODELING LIVER FIBROSIS WITH LIVER ORGANOID HEPATOLOGY. 2021.10; 74 825A.

  131. Lansing F., Mukhametzyanova L., Rojo-Romanos T., Iwasawa K., Kimura M., Paszkowski-Rogacz M., Karpinski J., Grass T., Sonntag J., Schneider P. M., Guenes C., Hoersten J., Schmitt L. T., Rodriguez-Muela M., Knoefler R., Takebe T., Buchholz F.. Correction of a Factor VIII genomic inversion with designer-recombinases HUMAN GENE THERAPY. 2021.10; 32 (19-20): A16-A17.

  132. 武部 貴則, 谷口 英樹. iPS細胞由来ミニ肝臓と血漿蛋白産生 日本輸血細胞治療学会誌. 2017.06; 63 (3): 311. ( 医中誌 )

  133. 谷口 英樹, 武部 貴則. 【再生医療2015　幹細胞と疾患iPS細胞の研究最前線】 (第4章)臨床応用　肝疾患領域における再生医療のトピックス 実験医学. 2015.02; 33 (2): 332,164-337,164. ( 医中誌 )

< 前のページ - 次のページ >

  • 1
このページの先頭へ▲