論文・総説 - 武部　貴則

1. Sheth M, Sharma M, Lehn M, Reza HAl, Takebe T, Takiar V, Wise-Draper T, Esfandiari L. Three-dimensional matrix stiffness modulates mechanosensitive and phenotypic alterations in oral squamous cell carcinoma spheroids APL Bioengineering. 2024.09; 8 (3): 036106.

2. Lutolf MP, Radisic M, Beekman J, Huh DD, Huch M, Turco MY, Niloofar Z, Birgani T, Gao D, Yao R, Lin H, Takebe T. In vitro human cell-based models: What can they do and what are their limitations? Cell. 2024.08;

3. Liu YJ, Kimura M, Li X, Sulc J, Wang Q, López SR, Scantlebery AML, Strotjohann K, Ayala HG, Vijayakumar A, Myers RP, Ivanisevic J, Houtkooper RH, Subramanian GM, Takebe T, Auwerx J. ACMSD inhibition corrects fibrosis, inflammation, and DNA damage in MASLD/MASH Journal of Hepatology. 2024.08;

4. Quach S, Lewis K, Iwasawa K, Milton Y, Guillot Ahmed YA, Takebe T, Behncke RY, Rezvani M. SAT-180 Targeting neutrophil injury-pathways and fibrogenesis in nonparenchymal immune tissue-like liver organoids generated from human induced pluripotent stem cells Journal of Hepatology. 2024.06; 80 S302-S303.

5. Toshiya Nishimura, Takanori Takebe. Synthetic human gonadal tissues for toxicology Reproductive Toxicology. 2024.04; 108598.

6. Masaki Kimura, Takanori Takebe. Cellotype–phenotype associations using ‘organoid villages Trends in Endocrinology & Metabolism. 2024.04; 35 (6): 462-465.

7. Miao Y, Tan C, Pek NM, Yu Z, Iwasawa K, Kechele DO, Sundaram N, Pastrana-Gomez V, Kishimoto K, Yang M, Jiang C, Tchieu J, Whitsett JA, McCracken KW, Rottier RJ, Kotton DN, Helmrath MA, Wells JM, Takebe T, Zorn AM, Chen Y, Guo M, Gu M. Deciphering Endothelial and Mesenchymal Organ Specification in Vascularized Lung and Intestinal Organoids bioRxiv. 2024.02;

8. Jurickova I, Dreskin BW, Angerman E, Bonkowski E, Tominaga K, Iwasawa K, Braun T, Takebe T, Helmrath MA, Haberman Y, Wells JM, Denson LA. Eicosatetraynoic Acid Regulates Pro-Fibrotic Pathways in an Induced Pluripotent Stem Cell Derived Macrophage:Human Intestinal Organoid Model of Crohn’s Disease bioRxiv. 2024.01;

9. Naraoka Y, Mabuchi Y, Kiuchi M, Kumagai K, Hisamatsu D, Yoneyama Y, Takebe T, Akazawa C. Quality Control of Stem Cell-Based Cultured Meat According to Specific Differentiation Abilities Cells. 2024.01; 13 (2): 135.

10. Sho Osonoi, Takanori Takebe. Organoid-guided precision hepatology for metabolic liver disease Journal of Hepatology. 2024.01; 80 (5): 805-821.

11. Múnera JO, Kechele DO, Bouffi C, Qu N, Jing R, Maity P, Enriquez JR, Han, Campbell I, Mahe MM, McCauley HA, Zhang X, Sundaram N, Hudson JR, Zarsozo-Lacoste A, Pradhan S, Tominaga K, Sanchez JG, Weiss AAChatuvedi P, Spence JR, Hachimi M, North T, Daley GQ, Mayhew CN, Hu Y, Takebe T, Helmrath MA, Wells JM. Development of functional resident macrophages in human pluripotent stem cell-derived colonic organoids and human fetal colon Cell Stem Cell. 2023.11; 30 (11): 1434-1451.

12. Reza H, Farooqui Z, Reza A, Conroy C, Iwasawa K, Ogura Y, Okita K, Osafune K, Takebe T. Synthetic augmentation of bilirubin metabolism in human pluripotent stem cell-derived liver organoids Stem Cell Reports. 2023.11; 8 (11):

13. Kawakami E, Saiki N, Yoneyama Y, Takayama K, Nio Y, Takebe T. Complement factor D targeting protects endotheliopathy in organoid and monkey models of COVID-19 Cell Stem Cell. 2023.10; 30 (10): 1315-1330.

14. Matsuzaki T, Kawano Y, Horikiri M, Shimokawa Y, Yamazaki T, Okuma N, Koike H, Kimura M, Kawamura R, Yoneyama Y, Furuichi Y, Hakuno F, Takahashi SI, Nakabayashi S, Okamoto S, Nakauchi H, . Preparation of mechanically patterned hydrogels for controlling the self-condensation of cells STAR protocols. 2023.07; 4 (3): 102471.

15. Tamaoki N, Siebert S, Maeda T, Ha NH, Good ML, Huang Y, Vodnala SK, Haro-Mora JJ, Uchida N, Tisdale JF, Sweeney CL, Choi U, Brault J, Koontz S, Malech HL, Yamazaki Y, Isonaka R, Goldstein DS, Kimura M, Takebe T, Zou J, Stroncek DF, Robey PG, Kruhlak MJ, Restifo NP, Vizcardo R.. Self-organized yolk sac-like organoids allow for scalable generation of multipotent hematopoietic progenitor cells from induced pluripotent stem cells Cell Reports Methods. 2023.04; 3 (4): 100460.

16. Fujii T, Yoneyama Y, Kinebuchi A, Ozeki N, Maeda S, Saiki N, Fengshi Chen-Yoshikawa T.F., Date H, Nishiwaki K, Takebe T. Enteral liquid ventilation oxygenates a hypoxic pig model iScience. 2023.03; 26 (3):

17. Kang S, Kimura M, Shrestha S, Lewis P, Lee S, Cai Y, Joshi P, Acharya P, Liu J, Yang Y, Sanchez J, Ayyagari S, Alsberg E, Wells J, Takebe T, Lee M. A Pillar and Perfusion Plate Platform for Robust Human Organoid Culture and Analysis bioRxiv. 2023.03;

18. Kimura M, Iguchi T, Iwasawa K, Dunn A, Thompson W, Yoneyama Y, Chaturvedi P, Zorn A, Wintzinger M, Quattrocelli M, Watanabe-Chailland M, Zhu G, Fujimoto M, Kumbaji M, Kodaka A, Gindin Y, Chung C, Myers R, Subramanian G, Hwa V, Takebe T. En masse organoid phenotyping informs metabolic-associated genetic susceptibility to NASH Cell. 2022.10; 185 (22): 4216-4232.e16.

19. Liu Y, Kimura M, Vijayakumar A, Murakami E, Takebe T, Subramanian M, Auwerx J. ENHANCEMENT OF DE NOVO NAD plus BIOSYNTHESIS BY NOVEL ACMSD INHIBITORS IMPROVES MITOCHONDRIAL FUNCTION IN iPSC-DERIVED HUMAN LIVER ORGANOID Hepatology. 2022.10; 76 S706.

20. Kimura M, Chuang JC, Vijayakumar A, Murakami E, Huss RS, Myers RP, Subramanian, M Takebe T. ENHANCED LIPOGENESIS ASSOCIATED WITH A HIGH-RISK GCKR VARIANT (rs1260326) IS EFFECTIVELY SUPPRESSED BY TLC-2716, A NOVEL, LIVER-TARGETED LXR INVERSE AGONIST IN STEATOTIC HUMAN … HEPATOLOGY. 2022.10; 76 S1280-S1281.