Personnel Information

写真a

HASHIMOTO Yoshihide


Job title

Assistant Professor

Campus Career 【 display / non-display

  • 2014.12
    -
    2015.10
    Tokyo Medical and Dental University, Institute of Biomaterials and Bioengineering, Acellular Tissue and Regenerative Medelical Material, Assistant Professor
  • 2015.10
    -
    2023.03
    Tokyo Medical and Dental University, Institute of Biomaterials and Bioengineering, Biofunctional Restoration, Material-based Medical Engineering, Assistant Professor
  • 2015.10
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Life Science and Technology, Life Science and Technology, Material-Based Medical Engineering, Assistant Professor
  • 2018.04
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Biomedical Sciences and Engineering, Division of Biomedical Engineering, Department of Material-based Medical Engineering, Assistant Professor
  • 2023.04
    -
    Now
    Tokyo Medical and Dental University, Institute of Biomaterials and Bioengineering, -, -, Assistant Professor

Research Areas 【 display / non-display

  • Biomedical engineering

  • Polymer chemistry

  • Bio chemistry

 

Published Papers & Misc 【 display / non-display

  1. Say sreypich, Mika Suzuki, Yoshihide Hashimoto, Tsuyoshi Kimura, Akio Kishida. Effect of multi arm-PEG-NHS (polyethylene glycol n-hydroxysuccinimide) branching on cell adhesion to modified decellularized bovine and porcine pericardium Journal of Materials chemistry B. 2024.12; 12 1244-1256. ( DOI )

  2. Shota Toda, Yoshihide Hashimoto, Naoko Nakamura, Masahiro Yamada, Ryusuke Nakaoka, Wataru Nomura, Masaya Yamamoto, Tsuyoshi Kimura, Akio Kishida. Characteristics of macrophage aggregates prepared by rotation culture and their response to polymeric materials Journal of Artificial Organs. 2024.01;

  3. Kohei Yabuuchi, Toru Katsumata, Tsuyoshi Shimoboji, Yoshihide Hashimoto, Tsuyoshi Kimura, Kazunari Akiyoshi, Akio Kishida. Variable swelling behavior of and drug encapsulation in a maleimide-modified hyaluronic acid nanogel-based hydrogel Polymer Journal. 2024.01;

  4. Tsuyoshi Kimura, Hanako Maeda, Moeko Hagiwara, Yoshihide Hashimoto, Naoko Nakamura, Wataru Nomura, Tadao Tanabe, Mako Kobayashi, Masaya Yamamoto, Takahide Matsushima, Hiroshi Asahara, Akio Kishida. Evaluation of Proinflammatory Response to Polymeric Materials Using a Macrophage Cell Line Genetically Tagged with a Luminescent Peptide Advanced Biomedical Engineering. 2024; 13 43-51.

  5. Yoshihide Hashimoto, Akitatsu Yamashita, Masaki Tabuchi, Yongwei Zhang, Seiichi Funamoto, Akio Kishida. Fibrin Hydrogel Layer-Anchored Pericardial Matrix Prevents Epicardial Adhesion in the Severe Heart Adhesion-Induced Miniature Pig Model. Ann Biomed Eng. 2023.12; ( PubMed, DOI )

  6. Kohei Yabuuchi, Mika Suzuki, Chen Liang, Yoshihide Hashimoto, Tsuyoshi Kimura, Kazunari Akiyoshi, Akio Kishida.. Preparation of cholesterol-modified hyaluronic acid nanogel-based hydrogel and the inflammatory evaluation using macrophage-like cells Gels. 2023.10; 9 (11): 866. ( DOI )

  7. Mika Suzuki, Tsuyoshi Kimura, Yuta Nakano, Mako Kobayashi, Masahiro Okada, Takuya Matsumoto, Naoko Nakamura, Yoshihide Hashimoto, Akio Kishida. Preparation of mineralized pericardium by alternative soaking for soft-hard interregional tissue application. Journal of Biomedical Materials Research Part A. 2023.02; 111 (2): 198-208. ( PubMed, DOI )

  8. Wen-Jin Ho, Mako Kobayashi, Kozue Murata, Yoshihide Hashimoto, Kenji Izumi, Tsuyoshi Kimura, Hideo Kanemitsu, Kazuhiro Yamazaki, Tadashi Ikeda, Kenji Minatoya, Akio Kishida, Hidetoshi Masumoto. A novel approach for the endothelialization of xenogeneic decellularized vascular tissues by human cells utilizing surface modification and dynamic culture. Scientific Reports. 2022.12; 12 (1): 22294. ( PubMed, DOI )

  9. Mako Kobayashi, Naoki Ishida, Yoshihide Hashimoto, Jun Negishi, Hideki Saga, Yoshihiro Sasaki, Kazunari Akiyoshi, Tsuyoshi Kimura, Akio Kishida. Extraction and biological evaluation of atrix-bound nanovesicles (MBVs) from high-hydrostatic pressure-decellularized tissues. Int J Mol Sci. 2022.08; 23 (16): ( PubMed, DOI )

  10. Mika Suzuki、Tsuyoshi Kimura、Yukina Yoshida、Mako Kobayashi、Yoshihide Hashimoto、Hironobu Takahashi、Tatsuya Shimizu、Shota Anzai、Naoko Nakamura、Akio Kishida. In Vitro Tissue Reconstruction Using Decellularized Pericardium Cultured with Cells for Ligament Regeneration Polymers. 2022.06; 14 (12): ( DOI )

  11. Mika Suzuki, Tsuyoshi Kimura, Yukina Yoshida, Mako Kobayashi, Yoshihide Hashimoto, Hironobu Takahashi, Tatsuya Shimizu, Shota Anzai, Naoko Nakamura, Akio Kishida. In vitro tissue reconstruction using decellularized pericardium cultured with cells for ligament regeneration Polymers. 2022.06; 14 (12): 2351. ( DOI )

  12. Yoshihide Hashimoto, Akitatsu Yamashita, Jun Negishi, Tsuyoshi Kimura, Seiichi Funamoto, and Akio Kishida. 4-Arm PEG-Functionalized Decellularized Pericardium for Effective Prevention of Postoperative Adhesion in Cardiac Surgery ACS Biomaterials Science & Engineering . 2022.01; 8 (1): 261-272. ( DOI )

  13. Shunji Kurokawa,Yoshihide Hashimoto,Seiichi Funamoto,Kozue Murata,Akitatsu Yamashita,Kazuhiro Yamazaki,Tadashi Ikeda,Kenji Minatoya,Akio Kishida,Hidetoshi Masumoto . In vivo recellularization of xenogeneic vascular grafts decellularized with high hydrostatic pressure method in a porcine carotid arterial interpose model PLoS One. 2021.07; 16 (7): ( DOI )

  14. Tsuyoshi Kimura, Rino Tokunaga, Yoshihide Hashimoto, Naoko Nakamura, Akio Kishida. Tumor growth suppression by implantation of an anti-CD25 antibody-immobilized material near the tumor via regulatory T cell capture Science and Technology of Advanced Materials. 2021.06; 22 (1): 607-615.

  15. Mako Kobayashi,Masako Ohara,Yoshihide Hashimoto,Naoko Nakamura,Toshiya Fujisato,Tsuyoshi Kimura,Akio Kishida. Effect of luminal surface structure of decellularized aorta on thrombus formation and cell behavior PLOS ONE. 2021.05; 16 (5): e0246221. ( DOI )

  16. Kotaro Yanagisawa, Seiichi Funamoto, Yoshihide Hashimoto, Jun Negishi. Introduction of cells into porous Poly (L-lactic) acid scaffolds using impregnation techniques Tissue Eng Part C: Methods. 2020.12; 26 (12): 608-616. ( DOI )

  17. Masaki Watanabe, Hanao Maedam, Yoshihide Hashimoto, Tsuyorhi Kimura, Akio Kishida. Protein adsorption and cell adhension behavior of engineering plastics plasticized by supercritical carbon dioxide Dent Mater J. 2020.12; 39 (6): 1033-1038. ( DOI )

  18. Mako Kobayashi, Masao Ohara, Yoshihide Hashimoto, Naoko Nakamura, Toshiya Fujisato, Tsuyoshi Kimura, Akio Kishida. In vitro evaluation of surface biological properties of decellulaized cardiovasucular use J Mater Chem B. 2020.12; 8 10977-10989. ( DOI )

  19. Yongwei Zhang, Kwangwoo Nam, Tsuyoshi Kimura, Pingli Wu, Naoko Nakamura, Yoshihide Hashimoto, Seiichi Funamoto, Akio Kishida. Preparation of gradient-type biological tissue–polymer complex for interlinking device Mater Sci Eng C-Mater Biol App. 2020.09; 114 111017. ( DOI )

  20. Mako Kobayashi,Junpei Kadota,Yoshihide Hashimoto,Toshiya Fujisato,Naoko Nakamura,Tsuyoshi Kimura,Akio Kishida. Elastic Modulus of ECM Hydrogels Derived from Decellularized Tissue A ects Capillary Network Formation in Endothelial Cells Int J Mol Sci. 2020.09; 21 (17): 6304. ( DOI )

  21. Masaki Watanabe, Yoshihide Hashimoto, Tsuyoshi Kimura, Akio Kishida. Characterization of engineering plastics plasticized using supercritical CO2 Polymers. 2020.01; 12 (1): 134. ( DOI )

  22. Jun Negishi, Seiichi Funamoto, Yoshihide Hashimoto, Kotaro Yanagisawa. PLA-collagen composite scaffold fabrication by vacuum pressure impregnation Tissue Eng Part C: Methods. 2019.12; 25 (12): 742-747. ( DOI )

  23. Yoshihide Hashimoto, Seiichi Funamoto, Shuji Sasaki, Jun Negishi, Shinya Hattori, Takako Honda, Tsuyoshi Kimura, Hisatoshi Kobayashi, Akio Kishida. Re-epithelialization and remodeling of decellularized corneal matrix in a rabbit corneal epithelial wound model Mater Sci Eng C-Mater Biol App. 2019.09; 102 238-246. ( DOI )

  24. Tsuyoshi Kimura, Mayuka Kondo, Yoshihide Hashimoto, Toshiya Fujisato, Naoko Nakamura, Akio Kishida. Surface topography of PDMS replica transferred from various decellularized aortic lumens affects cellular orientation ACS Biomater Sci Eng. 2019.04; 5 (11): 5721-5726. ( DOI )

  25. Yoshihide Hashimoto, Sada-atsu Mukai, Yoshihiro Sasaki, Kazunari Akiyoshi. Nanogel tectonics for tissue engineering: Protein delivery systems with nanogel chaperones Adv Healthc Mater. 2018.12; 7 (23): e1800729. ( DOI )

  26. Yongwei Zhang, Takuya Iwata, Kwangwoo Nam, Tsuyoshi Kimura, Pingli Wu, Naoko Nakamura, Yoshihide Hashimoto, Akio Kishida. Water absorption by decellularized dermis Heliyon. 2018.04; 4 (4): e00600. ( DOI )

  27. Jun Negishi, Yoshihide Hashimoto, Akitatsu Yamashita, Yongwei Zhang, Tsuyoshi Kimura, Akio Kishida, Seiichi Funamoto. Evaluation of small-diameter vascular grafts reconstructed from decellularized aorta sheets J Biomed Mater Res Part A. 2017.05; 105 (5): 1293-1298. ( PubMed, DOI )

  28. Hiroki Maeda, Hiroshi Kobayashi, Takayuki Miyahara, Yoshihide Hashimoto, Kazunari Akiyoshi, Shohei Kasugai. Effects of a polysaccharide nanogel-crosslinked membrane on wound healing J Biomed Mater Res Part B Appl Biomater. 2017.04; 105 (3): 544-550. ( PubMed, DOI )

  29. Tsuyoshi Kimura, Naoko Nakamura, Kanji Umeda, Yoshihide Hashimoto, Akio Kishida. Capture and release of cells using a temperature-responsive surface that immobilizes an antibody through DNA duplex formation J Biomater Sci Polym Ed. 2017.03; 28 (10-12): 1172-1182. ( PubMed, DOI )

  30. Gunce E. Cinay, Pelin Erkoc, Mohammad Alipour, Yoshihide Hashimoto, Yoshihiro Sasaki, Kazunari Akiyoshi, Seda Kizilel. Nanogel-integrated pH responsive composite hydrogels for controlled drug delivery ACS Biomaterials Science and Engineering. 2017.01; 3 (3): 370-380. ( DOI )

  31. Jun Negishi, Yoshihide Hashimoto, Akitatsu Yamashita, Tsuyoshi Kimura, Akio Kishida, Seiichi Funamoto. Histological structure affects recellularization of decellularized arteries Mater Sci Eng C Mater Biol Appl. 2017.01; 70 (Pt 1): 450-455. ( PubMed, DOI )

  32. Tsuyoshi Kimura, Naoko Nakamura, Nao Sasaki, Yoshihide Hashimoto, Shimon Sakaguchi, Shunsaku Kimura, Akio Kishida. Capture and release of target cells using a surface that immobilizes an antibody via desthiobiotin–avidin interaction Sens Mater. 2016.12; 28 (12): 1255-1263.

  33. Yoshihide Hashimoto, Shinya Hattori, Shuji Sasaki, Takako Honda, Tsuyoshi Kimura, Seiichi Funamoto, Hisatoshi Kobayashi, Akio Kishida. Ultrastructural analysis of the decellularized cornea after interlamellar keratoplasty and microkeratome-assisted anterior lamellar keratoplasty in a rabbit model Sci Rep. 2016.06; 6 27734. ( PubMed, DOI )

  34. Yoshihide Hashimoto, Sada-atsu Mukai, Shin-chi Sawada, Yoshihiro Sasaki, Kazunari Akiyoshi. Advanced artificial extracellular matrices using amphiphilic nanogel-crosslinked thin films to anchor adhesion proteins and cytokines ACS Biomater Sci Eng. 2016.02; 2 (3): 375-384.

  35. Yoshihide Hashimoto, Seiichi Funamoto, Shuji Sasaki, Jun Negishi, Takako Honda, Shinya Hattori, Kwangwoo Nam, Tsuyoshi Kimura, Manabu Mochizuki, Hisatoshi Kobayashi, Akio Kishida. Corneal Regeneration by Deep Anterior Lamellar Keratoplasty (DALK) Using Decellularized Corneal Matrix PLoS ONE. 2015.07; 10 (7): e0131989. ( PubMed, DOI )

  36. Yoshihide Hashimoto, Sada-atsu Mukai, Shin-ichi Sawada, Yoshihiro Sasaki, Kazunari Akiyoshi. Nanogel tectonic porous gel loading biologics, nanocarriers, and cells for advanced scaffold Biomaterials. 2015.01; 37 107-115. ( PubMed, DOI )

  37. Hidetaka Fujii, Masaharu Shin-Ya, Shigeo Takeda, Yoshihide Hashimoto, Sada-atsu Mukai, Shin-ichi Sawada, Tetsuya Adachi, Kazunari Akiyoshi, Tsuneharu Miki, Osam Mazda. Cycloamylose-nanogel drug delivery system-mediated intratumor silencing of the vascular endothelial growth factor regulates neovascularization in tumor microenvironment Cancer Sci. 2014.12; 105 (12): 1616-1625. ( PubMed, DOI )

  38. Jun Negishi, Kwangwoo Nam, Tsuyoshi Kimura, Yoshihide Hashimoto, Seiichi Funamoto, Tetsuya Higami, Toshiya Fujisato, Akio Kishida. Fabrication of a heparin-PVA complex hydrogel for application as a vascular access J Biomed Mater Res Part B Appl Biomater. 2014.10; 102 (7): 1426-1433. ( PubMed, DOI )

  39. Jun Negishi, Yoshihide Hashimoto, Kwangoo Nam, Tsuyoshi Kimura, Seiichi Funamoto, Akio Kishida. Application of a vacuum pressure impregnation technique for rehydrating decellularized tissues Tissue Eng Part C: Methods. 2014.09; 20 (9): 724-730. ( PubMed, DOI )

  40. Masako Yokota, Yukiho Kobayashi, Jumpei Morita, Hiroyuki Suzuki, Yoshihide Hashimoto, Yoshihiro Sasaki, Kazunari Akiyoshi, Keiji Moriyama. Therapeutic effect of nanogel-based delivery of soluble FGFR2 with S252W mutation on craniosynostosis PLoS ONE. 2014.07; 9 (7): e101693. ( PubMed, DOI )

  41. Kwangwoo Nam, Yuuki Sakai, Yoshihide Hashimoto, Tsuyoshi Kimura, Akio Kishida. Fabrication of a heterostructural fibrillated collagen matrix for the regeneration of soft tissue function Soft Matter. 2012.01; 8 (2): 472-480. ( DOI )

  42. Yoshihide Hashimoto, Seiichi Funamoto, Tsuyoshi Kimura, Kwangwoo Nam, Toshiya Fujisato, Akio Kishida. The effect of decellularized bone/bone marrow produced by high-hydrostatic pressurization on the osteogenic differentiation of mesenchymal stem cells Biomaterials. 2011.10; 32 (29): 7060-7067. ( PubMed, DOI )

  43. Kwangwoo Nam, Rie Fukaya, Yoshihide Hashimoto, Yukiko Ito, Tsuyoshi Kimura, Akio Kishida. Human Mesenchymal Stem cell behavior on concentrated polymer brushes presenting different surface stiffness Chem Lett. 2010.11; 39 (11): 1164-1165. ( DOI )

  44. Yoshihide Hashimoto, Seiichi Funamoto, Shuji Sasaki, Takako Honda, Shinya Hattori, Kwangwoo Nam, Tsuyoshi Kimura, Manabu Mochizuki, Toshiya Fujisato, Hisatoshi Kobayashi, Akio Kishida. Preparation and characterization of decellularized cornea using high-hydrostatic pressurization for corneal tissue engineering Biomaterials. 2010.05; 31 (14): 3941-3948. ( PubMed, DOI )

  45. Seiichi Funamoto, Kwangwoo Nam, Tsuyoshi Kimura, Ayako Murakoshi, Yoshihide Hashimoto, Kazuo Niwaya, Soichiro Kitamura, Toshiya Fujisato, Akio Kishida. The use of high-hydrostatic pressure treatment to decellularize blood vessels Biomaterials. 2010.05; 31 (13): 3590-3595. ( PubMed, DOI )

  46. Chiaki Yoshikawa, Yoshihide Hashimoto, Shinya Hattori, Takako Honda, Kun Zhang, Dohiko Terada, Akio Kishida, Yoshinobu Tsujii, Hisatoshi Kobayashi. Suppression of cell adhesion on well-defined concentrated polymer brushes of hydrophilic polymer Chem Lett. 2010.02; 39 (2): 142-143. ( DOI )

  47. Shuji Sasaki, Seiichi Funamoto, Yoshihide Hashimoto, Tsuyoshi Kimura, Takako Honda, Shinya Hattori, Hisatoshi Kobayashi, Akio Kishida, Manabu Mochizuki. In vivo evaluation of a novel scaffold for artificial corneas prepared by using ultrahigh hydrostatic pressure to decellularize porcine corneas Mol Vis. 2009.10; 15 2022-2028. ( PubMed )

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Books etc 【 display / non-display

  1. Yoshihide Hashimoto. Research and development on therapeutic materials for corneal stromal disease consisting of transparent decellularised porcine corneas. 2023.09

  2. Yoshihide Hashimoto, Seiichi Funamoto, Shuji Sasaki, Tsuyoshi Kimura, Hisatoshi Kobayashi, Akio Kishida. Decellularized matrix for corneal tissue engineering: Recent advances in development and clinical potential, Decellularized Extracellular Matrix: Characterization, Fabrication and Applications. RSC Publishing, 2019.12 Chapter 12 Decellularized matrix for corneal tissue engineering: Recent advances in development and clinical potential (ISBN : 978-1-78801-467-0)

  3. Akio Kishida, Seiichi Funamoto, Jun Negishi, Yoshihide Hashmoto, Kwangoo Nam, Tsuyoshi Kimura, Toshiya Fujisato, Hisatoshi Kobayashi. Tissue Engineering with Natural Tissue Matrics, Advances in Science and Technology. Trans Tech Publications, Switzerland, 2010.10

Conference Activities & Talks 【 display / non-display

  1. Mika Suzuki, Tsuyoshi Kimura, Varja cuculuvic, Ruri Ishigaki, Yoshihide Hashimoto, Takahide Matsushima, Hiroshi Asahara, Wataru Nomura, Kishida Akio. Evaluation of immunogenicity of various treated decellularized tissue using gene-modified THP-1. Materials Research Meeting (MRM) 2023 2023.12.16 Kyoto

  2. Chen Liang, Tsuyoshi Kimura, Mika Suzuki, Yoshihide Hashimoto, Takahide Matsushima, Hiroshi Asahara, Wataru Nomura, Tadao Tanabe, Masaya Yamamoto, Naoko Nakamura, Akio Kishida. Evaluation of microplastics using Caco-2/THP-1 co-culture. The 3rd Materials Research Meeting (MRM2023) 2023.12.15

  3. Mako Kobayashi,Jun Negishi,Yoshihide Hashimoto,Masaya Yamamoto,Yoshihiro Sasaki,Kazunari Akiyoshi,Tsuyoshi Kimura,Akio Kishida. The 11th Pacific Rim International Conference on Advanced Materials and Processing. The 11th Pacific Rim International Conference on Advanced Materials and Processing 2023.11.19 Korea

  4. Tsuyoshi Kimura,Cehn Liang,Mika Suzuki,Yoshihide Hashimoto,Tadao Tanabe,Masaya Yamamoto,Akio Kishida. Evaluation of biological response to materials using intestinal epithelial cells and macrophages. The 11th Pacific Rim International Conference on Advanced Materials and Processing 2023.11.19 Korea

  5. 鈴木美加,木村剛,岡田正弘,松本卓也,山田将博,江草宏, 中村奈緒子,岸田晶夫. 硬-軟境界組織応用を目指した石灰化dECM膜のin vivo骨親和性評価. バイオマテリアル学会 2023.11.06 神戸

  6. Akio Kishida, Hanako Maeda, Moeko Hagiwara, Yoshihide Hashimoto, Mako Kobayashi, Tsuyoshi Kimura. Pro-inflammatory characterization of biomaterials using genetically modified THP-1 cells. 33rd Annual Conference of European Society for Biomaterials 2023.09.04 Davos, Switzerland.

  7. T. Kimura, M.Suzuki, Y. Hashimoto, M. Okada, T. Matsumoto, N. Nakamura, Akio Kishida. Development of soft-hard interregional tissue by mineralization of decellularized membrane. Biomaterials International 2023 2023.07.30 Hokkaido, Japan

  8. Sreypich Say, Yoshihide Hashimoto, Tsuyoshi Kimura, Akio Kishida. Fabrication and characterization of linear and branch PEGNHS to modify the porcine and bovine pericardium. 第72回高分子学会年次大会 2023.05.24 群馬県

  9. Tsuyoshi Kimura, Mika Suzuki, Yoshihide Hashimoto, Masahiro Okada, Takuya Matsumoto, Naoko Nakamura, Akio Kishida. Development of soft-hard interregional tissue using a mineralized dECM membrane. Society For Biomaterials 2023 2023.04.18 USA

  10. Yoshihide Hashimoto, Takuya Akizawa, Moeko Hagiwara, Tsuyoshi Kimura, Akio Kishida. Cellular behaviors of human skeletal muscle satellite cells on tissue specific extracellular matrix coating and hydrogels. TERMIS EU 2023 2023.03.28 Manchester, UK

  11. 鈴木美加, 木村剛, 橋本良秀, 岡田正弘,松本卓也,高橋宏信, 清水達也, 中村奈緒子, 岸田晶夫. 歯根膜としての応用を目指した片面石灰化脱細胞化膜の調製. 第22回 日本再生医療学会総会 2023.03.25

  12. 木村剛、徳野陽子、内田健哉、萩原萌子、橋本良秀、岸田晶夫. 生体組織を模擬した 3D 配向コラーゲンナノファイバ構造体の皮膚フラップモデル評価. 第22回日本再生医療学会総会 2023.03.23 京都府

  13. 鈴木美加, 木村剛, 橋本良秀, 岡田正弘,松本卓也,高橋宏信, 清水達也, 中村奈緒子, 岸田晶夫. 硬-軟組織への適用を目指した石灰化脱細胞化組織の創製および評価. ライフサポート学会 2023.03.13

  14. WenJin Ho, Hidetoshi Masumoto, Mako Kobayashi, Kozue Murata, Tadashi Ikeda, Yoshihide Hashimoto, Tsuyoshi Kimura, Kenji Minatoya, Akio Kishida. A novel approach for pre-implant endothelialization of xenogeneic decellularized vascular tissues by human endothelial cells utilizing tissue surface modification and dynamic culture. American Heart Association 2022 Scientific Sessions 2022.11.04

  15. Yoshihide Hashimoto, Takuya Akizawa, Moeko Hagiwara, Mako Kobayashi, Tsuyoshi Kimura, Akio Kishida. Cellular behaviors of human skeletal muscle satellite cells on tissue specific extracellular matrix coating and hydrogels. Visual-JW 2022 2022.10.25

  16. Mako Kobayashi、Naoki Ishida、Yoshihide Hashimoto、Jun Negishi、Hideki Saga、Takehiro Iwanaga、Yoshihiro Sasaki、Kazunari Akiyoshi、Tsuyoshi Kimura、Akio Kishida. The effects of matrix-bound nanovesicles(MBVs) derived from high-hydrostatic pressure decellularized tissued on neural regeneration. TERMIS-AP 2022 2022.10.05 South Korea

  17. Tsuyoshi Kimura、Mika Suzuki、Mako Kobayashi、Masahiro Okada、Takuya Matsumoto、Naoko Nakamura、Yoshihide Hashimoto、Akio Kishida. Development of a mineralized decellularized tissue for soft-hard inter-regional tissue application. TERMIS-AP 2022 2022.10.05 South Korea

  18. Mika Suzuki、Yuta Nakano、Yoshihide Hashimoto、Hironobu Takahashi、Tatsuya Shimizu、Noko Nakamura、Tsuyoshi Kimura、Akio Kishida. Recellularization of partially mineralized membranous decellularized tissue for locomotor regeneration. MRM2021 2021.12.13 神奈川

  19. Tsuyohi Kimura、Rino Tokunaga、Yoshihide Hashimoto、Naoko Nakamura、Akio Kishida. Tumor growth suppression by releasing cancer immune suppression using an anti-CD25 antibody-immobilized material. MRM2021 2021.12.13 神奈川

  20. Mika Suzuki, Yuta Nakano, Yoshihide Hashimoto, Hironobu Takahashi, Tatsuya Shimizu, Naoko Nakamura,Tsuyoshi Kimura, Akio Kishida . Preparation of a mineralized decellularized pericardium by alternate soaking for enhancing bone affinity. ISBE2021 2021.12.02 Web

  21. Tsuyoshi Kimura, Eri Yasuda, Yoshihide Hashimoto, Ikuro Suzuki, Naoko Nakamura, Akio Kishida. Classification of HHP and SDS decellularized tissue histology images using artificial intelligence. ISBE2021 2021.12.02 Web

  22. Yoshihide Hashimoto, Akitatsu Yamashita, Jun Negishi, Tsuyoshi Kimura, Seiichi Funamoto, Akio Kishida. Four-arm PEG-functionalized decellularized pericardium as an effective post-operative pericardial adhesion barrier. ISBE2021 2021.12.02 Web

  23. Tsuyoshi Kimura、Mika Suzuki、Yoshihide Hashimoto、Hironobu Takahashi、Tatsuya Shimizu、Naoko Nakamura、Akio Kishida. In vitro tissue reconstruction using decellularized pericardium cultured with cells for ligament regeneration. 2021 6th TERMIS-WC 2021.11.15 WEB開催

  24. Mako Kobayashi、Naoki Ishida、Yoshihide Hashimoto、Jun Negishi、Hideki Saga、Yoshihiro Sasaki、Kazunari Akiyoshi、Tsuyoshi Kimura、Akio Kishida. Extraction of matrix-bound nanovesicles (MBVs) from high-hydrostatic pressure decellularized tissue and evaluation on vascular endothelial cells. 2021 6th TERMIS-WC 2021.11.15 WEB開催

  25. Shota Toda、Yoshihide Hashimoto、Tsuyoshi Kimura、Akio Kishida. Preparation of macrophage adhering particles for immunological evaluation of biomaterials . 2021 6th TERMIS-WC 2021.11.15 WEB開催

  26. T. Kimura, J. Kadota, N. Nakamura, Y. Hashimoto, A. Kishida. Network formation of endothelial cells on decellularized ECM hydrogels. MRM2019 2019.12.10 Kanagawa, Japan

  27. A. Kishida, J. Kadota, N. Nakamura, Y. Hashimoto, T. Kimura. Network formation of endothelial cells on hydrogels derived from decellurarized matrices. TERMIS-AM Annual Congress and Exhibition 2019.12.02 Orland,USA

  28. M.Kobayashi, M,Ohara, Y. Hashimoto, N.Nakamura, T. Fujisato, T. Kimura, A. Kishida. Effect of basement membrane structure on cell behavior and function on decellularized aorta. TERMIS-AM Annual Congress and Exhibition 2019.12.02 Orland,USA

  29. S. Kurokawa, H. Masumoto, Y. Hashimoto, S. Funamoto, T. Ikeda, A. Kishida, K. Minatoya. Evaluation for patency and recellularization of decellularized vascular grafts with high hydrostatic pressure method in a xenotransplantation animal model. AHA 2019 2019.11.16 Philadelphia, USA

  30. Tsuyoshi Kimura, Rino Tokunaga, Yoshihide Hashimoto, Naoko Nakamura, Akio Kishida. Development of an implantable immunomodulatory material basaed on cell moving for cancer treatment. International Federation for Artificial Organs (IFAO) 2019 2019.11.13

  31. Tsuyoshi Kimura, Rino Tokunaga, Yoshihide Hashimoto, Naoko Nakamura, Akio Kishida. Development of an immunomodulatory biomaterial for cancer. International Conference on Materials and Systems for Sustainability (ICMaSS) 2019.11.02 Nagoya

  32. T.Kimura,J.Kadota,N.Nakamura,Y.Hashimoto,A.Kishida. Network formation of endothelial cells on Hydrogels Deriverd from Decellularized Matrices. TERMIS-AP 2019 2019.10.14 AUSTRALIA

  33. Akio Kishida,Rino Tokunaga,Yoshihide Hashimoto,Naoko Nakamura,Tsuyoshi Kimura. Development of an antibody-immobilized filter for capturing target Cells. ESB2019 2019.09.09 Dresden,Germany

  34. Tsuyoshi Kimura, Mako Kobayashi, Yoshihide Hashimoto, Toshiya Fujisato, Naoko Nakamura, Akio Kishida. A synthetic replica having surface morphology of decellularized tissue regulated orientation and shape of cells. SFB2019 Annual Meeting and Exposition 2019.04.03 Seattle, USA

  35. Mako Kobayashi, Mayuka Kondo, Ayano Tamura, Yoshihide Hashimoto, Toshiya Fujisato, Tsuyoshi Kimura, Akio Kishida. The effect of decellularization method on cell behavior on the decellularized aorta. SFB2019 Annual Meeting and Exposition 2019.04.03 Seattle,USA

  36. Junpei Kadota, Yoshihide Hashimoto, Toshiya Fujisato, Tsuyoshi Kimura, Akio Kishida. Characterization of ECM hydrogels prepared by different decellularization methods. 1st G’L’owing Polymer Symposium in KANTO 2018.12.15 Tokyo

  37. Mako Kobayashi, Mayuka Kondo, Ayano Tamura, Yoshihide Hashimoto,Toshiya Fujisato, Tsuyoshi Kimura, Akio Kishida. Cell behavior on the decellularized aorta with various basement membrane structures. 1st G’L’owing Polymer Symposium in KANTO 2018.12.15 Tokyo

  38. Tsuyoshi Kimura, Mayuka Kondo, Yoshihide Hashimoto, Toshiya Fujisato, Naoko Nakamura, Akio Kishida. Bio-surface replicated from decellularized tissue. 3rd International Sympodium on Creation of Life Innovation Materials for Interdiciplinary and International Researcher Development (iLIM-3) 2018.09.25 Tokyo

  39. Junpei Kadota, Yoshihide Hashimoto, Tsuyoshi Kimura, Akio Kishida. Preparation and characterization of ECM hydrogels derived from acellular urinary bladder matrix (UBM) and small intestinal submucosa (SIS). 3rd International Sympodium on Creation of Life Innovation Materials for Interdiciplinary and International Researcher Development (iLIM-3) 2018.09.25 Tokyo

  40. Tsuyoshi Kimura, Mayuka Kondo, Yoshihide Hashimoto, Toshiya Fujisato, Naoko Nakamura, Akio Kishida. Cellular behavior on decellularized tissue and its replica. Frontier 2018 2018.09.19 lausanne, Switzerland

  41. Junpei Kadota, Yoshihide Hashimoto, Tsuyoshi Kimura, Akio Kishida. In vitro microvascular network formation in/on hydrogels derived from decellularized tissues. Frontier 2018 2018.09.19 lausanne, Switzerland

  42. Tsuyoshi Kimura, Mayuka Kondo, Yoshihide Hashimoto, Naoko Nakamura, Akio Kishida. Basement membrane topology of decellularized aorta and its synthetic replica affected endothelial cell behavior. 5th TERMIS World Congress 2018.09.05 Kyoto

  43. Tsuyoshi Kimura, Mayuka Kondo, Yoshihide Hashimoto, Naoko Nakamura, Akio Kishida. Surface topology of decellularized aorta and its synthetic replica affected cell behavior. 5th TERMIS World Congress 2018.09.04 Kyoto

  44. Junpei Kadota, Yoshihide Hashimoto, Tsuyoshi Kimura, Akio Kishida. Preparation and characterization of hydrogels derived fromdecellularized urinary bladder matrix (UBM) and small intestinal submucosa (SIS). 5th TERMIS World Congress 2018.09.04 Kyoto

  45. Naruki Kimura, Kei Oya, Yoshihide Hashimoto, Seiichi Funamoto, Yuki Suzuki, Yuichiro Nawa, Akio Kishida, Takeo Nakano. Fabrication of visible marker on decellularized tissue for non-invasive techniques via sputtering. 5th TERMIS World Congress 2018.09.04 Kyoto

  46. Akio Kishida, Mayuka Kondo, Yoshihide Hashimoto, Toshiya Fujisato, Naoko Nakamura, Tsuyoshi Kimura.. Topological study of basement membrane of decellularized aorta using its synthetic replica. Finland-Japan Workshop: The next generation medical engineering in biomaterials 2018.06.17 Oulu, Finland

  47. Tsuyoshi Kimura, Naoko Nakamra, Yoshihide Hashimoto, Akio Kishida. Induction of immunogenic cell death of cancer cell by using chemical detergent treatment and its activation of immune system. Experimental Biology 2018 2018.04.21 SanDiego, USA

  48. T. Kimura, N. Nakamura, Y. Hashimoto, A. Kishida. Development of an antibody immobilizing device for label-free selective capture and collection of stem cells. TERMIS-AM 2017 2017.12.03

  49. Jun Negishi,Seiichi Funamoto,Yoshihide Hashimoto,Akitatsu Yamashita,Yongwei Zhang,Akio Kishida. Evaluation of Adult and Fetal Porcine Decellularized Tissues. 第2回生体医歯工学共同研究拠点国際シンポジウム 2017.11.09 東京都

  50. Naruki Kimura,Kei Oya,Yoshihide Hashimoto,Yuki Suzuki,Yuichiro Nawa,Seiichi Funamoto,Akio Kishida,Takeo Nakano. Sputter-deposition of Distinguishable Marker on Decellularized Tissue for Non-invasive Imaging Techniques. 第2回生体医歯工学共同研究拠点国際シンポジウム 2017.11.09 東京都

  51. Naoko Nakamura,Tsuyoshi Kimura,Yoshihide Hashimoto,Shimon Sakaguchi,Shunsaku Kimura,Akio Kishida. Label-free Capture and Collection of Target Cells Using a Surface Immobilizing Antibody Via Desthiobiotin-avidin Interaction. 第2回生体医歯工学共同研究拠点国際シンポジウム 2017.11.09 東京都

  52. Tsuyoshi Kimura,Takaaki Kubota,Naoko Nakamura,Yoshihide Hashimoto,Akio Kishida. Preparation of ICD induced cancer cells and activation of immune system. iLIM-2 2017.09.29 Nagoya,Japan

  53. Naruki Kimura, Yoshihide Hashimoto, Seiichi Funamoto, Akio Kishida, Yongwei Zhang, Akitatsu Yamashita, Kei Oya, Takeo Nakano. Fabrication of visible marker on decellularized tissue for ultrasonography via reactive sputtering. 2017 TERMIS-EU Conference 2017.06.26 Davos, Switzerland

  54. T. Kimura, N. Nakamura, Y. Hashimoto, S. Sakaguchi, S. Kimura, A. Kishida. Label-free capture of lymphocytes using a surface immobilizing antibody. 第66回 高分子学会年次大会 2017.05.29 千葉

  55. T.Kimura,N.Nakamura,Y.Hashimoto,A.Odawara,I.Suzuki,A.Kishida. Neural network reconstruction on sliced acellular brains for brain organoids. SFB2017 Annual Meeting and Exposition 2017.04.05 Minneapolis,USA

  56. T.Kimura,N.Nakamura,Y.Hashimoto,S.Sakaguchi,S.Kimura,A.Kishida. Selective Capture of Regulatory T Cells for Cancer Immunotherapy. SFB2017 Annual Meeting and Exposition 2017.04.05 Minneapolis,USA

  57. N. Nakamura, T. Kimura, Y. Hashimoto, T. Fujisato, T. Tsuji, A. Kishida . Periodontal tissue reconstruction using decellularized PDL matrix and 3D-printed tooth. 2016 TERMIS-Americas Conference & Exhibition 2016.12.11 San Diego,USA

  58. T. Kimura, N. Nakamura, Y. Hashimoto, S. Sakaguchi, S. Kimura, A. Kishida . Label-free capture and collection of target cells using a surface immobilizing antibody. 2016 TERMIS-Americas Conference & Exhibition 2016.12.11 San Diego,USA

  59. T. Kimura, N. Nakamura, Y. Hashimoto, S. Sakaguchi, S. Kimura, A. Kishida. Capture and release of lymphocyte on an antibody-immobilized surface. ICBS2016 2016.11.28 Tokyo,Japan

  60. T. Kimura, Y. Hashimoto, N. Nakamura, Y. Igari, T. Kubota, M. Kondo, S. Higashino, A. Kishida. Development of decellularaized tissues for controlling stem cell functions. The International Symposium on Visualization in Joining & Welding Science through Advanced Measurements and Simulation 2016.10.17 Osaka,Japan

  61. T. Kimura, P. Wu, H. Morita, N. Nakamura, Y. Hashimoto, A. Yamashita, S. Funamoto, T. Fujisato, A. Kishida. Mechanical and biological properties of small-diameter decellularized vascular graft covered by electrospun fibers. 9th International Conference on Fiber and Polymer Biotechnology 2016.09.07 osaka,Japan

  62. A. Yamashita, Y. Hashimoto, Y. Zhang, S. Funamoto, A. Kishida. Animal model for evaluation of anti-adhesive materials after open heart surgery. 9th International Conference on Fiber and Polymer Biotechnology 2016.09.07 Osaka,Japan

  63. Yoshihide Hashimoto, Jun Negishi, Masaki Tabuchi, Akitatsu Yamashita, Akio Kishida, Seiichi Funamoto. Evaluation of decellularized tissue powder using a rat myocardial infarct model. 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society 2015.08 Milan, Italy

  64. Yoshihide Hashimoto, Sada-atsu Mukai, Shin-ichi Sawada, Kazunari Akiyoshi. Fabrication of nanogel-crosslinked porous gels for tissue engineering applications. 41th CRS Annual Meeting & Exposition 2014.07 Chicago, USA

  65. Yoshihide Hashimoto, Sada-atsu Mukai, Shin-ichi Sawada, Kazunari Akiyoshi. Nanogel-crosslinked porous gel for tissue engineering. 7th International Forum for Environment and Energy 2014.03 Kyoto, Japan

  66. Sada-atsu Mukai, Yoshihide Hashimoto, Yoshiro Tahara, Shin-ichi Sawada, Kazunari Akiyoshi. Structural and mechanical properties of nanogel-crosslinked materials. KIPS-ESPCI Workshop on Polymer Science 2013 2013.11 Paris, France

  67. Yoshihide Hashimoto, Sada-atsu Mukai, Shin-ichi Sawada, Kazunari Akiyoshi. Nanogel crosslinked hydrogel with an interconnective porous structure for tissue engineering. 10th International Symposium on Frontiers in Biomedical Polymers 2013.06 Vancouver, Canada

  68. Yoshihide Hashimoto, Sada-atsu Mukai, Shin-ichi Sawada, Kazunari Akiyoshi. Biodegradable nanogel-crosslinked hydrogel with sustained drug release property for tissue engineering. 16th International Symposium on advances drug delivery systems 2013.01 SaltLake, USA

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Awards & Honors 【 display / non-display

  • TMDU-WISE Award Excellence Award,2023.02