Personnel Information

写真a

NOGAMI Ayako


Job title

Assistant Professor

Graduating School 【 display / non-display

  • Yamaguchi University, Faculty of Medicine, 2007.03, Graduated

Campus Career 【 display / non-display

  • 2011.04
    -
    2015.03
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Advanced Therapeutic Sciences, Hematology, Graduate Student
  • 2015.04
    -
    2016.03
    Tokyo Medical and Dental University, Medical Hospital, Hospital Departments, Department of Internal Medicine, Hematology, Senior Resident
  • 2016.04
    -
    2017.03
    Tokyo Medical and Dental University, Medical Hospital, Hospital Departments, Department of Internal Medicine, Hematology, Assistant Professor
  • 2017.04
    -
    2018.12
    Tokyo Medical and Dental University, Medical Hospital, Central Clinical Facilities, Clinical Laboratory, Assistant Professor
  • 2019.01
    -
    Now
    Tokyo Medical and Dental University, Medical Hospital, Central Clinical Facilities, Clinical Laboratory, Assistant Professor
 

Published Papers & Misc 【 display / non-display

  • Nagao T, Kurosu T, Umezawa Y, Nogami A, Oshikawa G, Tohda S, Yamamoto M, Miura O. Proliferation and survival signaling from both Jak2-V617F and Lyn involving GSK3 and mTOR/p70S6K/4EBP1 in PVTL-1 cell line newly established from acute myeloid leukemia transformed from polycythemia vera. PLoS ONE. 2014; 9 (1): e84746. ( PubMed, DOI )

  • Watanabe D, Nogami A, Okada K, Akiyama H, Umezawa Y, Miura O. FLT3-ITD Activates RSK1 to Enhance Proliferation and Survival of AML Cells by Activating mTORC1 and eIF4B Cooperatively with PIM or PI3K and by Inhibiting Bad and BIM. Cancers. 2019.11; 11 (12): ( PubMed, DOI )

  • Nogami Ayako, Okada Keigo, Ishida Shinya, Akiyama Hiroki, Umezawa Yoshihiro, Miura Osamu. Inhibition of the STAT5/Pim Kinase Axis Enhanecs Cytotoxic Effects of Proteasome Inhibitors on FLT3-ITD-Positive Cells by Cooperatively Inhibiting the mTORC1/4EBP1/S6K/Mcl-1 Pathway TRANSLATIONAL ONCOLOGY. 2019.02; 12 (2): 336-349. ( PubMed, DOI )

  • Ken Watanabe, Kota Yoshifuji, Tatsuya Saito, Tomoko Yamashita, Ayako Nogami, Chizuko Sakashita, Tetsuya Fukuda, Ayako Arai, Shuji Tohda, Norihiko Kawamata, Osamu Miura, Masahide Yamamoto. Follicular lymphoma accompanied by paraneoplastic pemphigus and bronchiolitis obliterans: a case report 2019.01; 60 (1): 7-11. ( ichushi )

  • Akiyama Hiroki, Umezawa Yoshihiro, Ishida Shinya, Okada Keigo, Nogami Ayako, Miura Osamu. Inhibition of USP9X induces apoptosis in FLT3-ITD-positive AML cells cooperatively by inhibiting the mutant kinase through aggresomal translocation and inducing oxidative stress CANCER LETTERS. 2019; 453 84-94. ( PubMed, DOI )

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Conference Activities & Talks 【 display / non-display

  • Ayako Nogami, Watanabe Daisuke, Keigo Okada, Hiroki Akiyama, Yoshihiro Umezawa, Toshikage Nagao, Shuji Tohdaand Osamu Miura. FLT3-ITD Enhances Proliferation and Survival of AML Cells through Activation of RSK1 to Upregulate the mTORC1/eIF4F Pathway Cooperatively with PIM or PI3K and to Inhibit Bad and Bim. 60th ASH Annual Meeting and Exposition 2019.12.01 FL, Orange County Convention Center

  • Ayako Nogami, Keigo Okada, Daisuke Watanabe, Hiroki Akiyama, Yoshihiro Umezawa, Shinya Ishida, Gaku Oshikawa, Shuji Tohda, Osamu Miura . Proteasome Inhibitors Downregulate the mTORC1/4EBP1/S6K/Mcl-1 Pathway Cooperatively with Inhibitors for The STAT5/Pim Kinase Pathway to Induce Apoptosis in FLT3-ITD-positive AML Cells. The 9th JSH International Symposium 2018 2018.07.28 Kyoto

  • Hiroki Akiyama, Yoshihiro Umezawa, Keigo Okada, Shinya Ishida, Ayako Nogami, and Osamu Miura. Deubiquitinase Inhibitor WP1130 Blocks FLT3-ITD to Induce Apoptosis in Leukemic Cells. 59th ASH Annual Meeting & Exposition 2017.12.17 Atlanta, GA, USA

  • Tomoko Yamashita, Hiroki Tsutsumi, Kota Yoshifuji, Tatsuya Saito, Yoshihiro Umezawa, Ayako Nogami, Ken Watanabe, Toshikage Nagao, Chizduko Sakashita, Masahide Yamamoto, Ayako Arai, Norihiko Kawamata, Osamu Miura, Tetsuya Fukuda. Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma with 11q Deletion. 第79回日本血液学会学術集会 2017.10.22

  • Hiroki Akiyama, Yoshihiro Umezawa, Keigo Okada, Shinya Ishida, Ayako Nogami, Toshikage Nagao, Osamu Miura. Deubiquitinase inhibitor WP1130 blocks JAK2-V617F to induce apoptosis in leukemic cells. The 79th Annual Meeting of the Japanese Society of Hematology 2017.10.21 Tokyo

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