Campus Career 【 display / non-display 】
-
2012.07-2018.03Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Cognitive and Behavioral Medicine, Neuroanatomy and Cellular Neurobiology, Assistant Professor
-
2018.04-2021.03Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Cognitive and Behavioral Medicine, Neuroanatomy and Cellular Neurobiology, Assistant Professor
-
2021.04-NowTokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Cognitive and Behavioral Medicine, Neuroanatomy and Cellular Neurobiology, Junior Associate Professor
Published Papers & Misc 【 display / non-display 】
-
Ayana Sugizaki, Keisuke Sato, Kazuyoshi Chiba, Kenta Saito, Masahiko Kawagishi, Yuri Tomabechi, Shalin B Mehta, Hirokazu Ishii, Naoki Sakai, Mikako Shirouzu, Tomomi Tani, Sumio Terada. POLArIS, a versatile probe for molecular orientation, revealed actin filaments associated with microtubule asters in early embryos Proceedings of the National Academy of Sciences of the United States of America. 2021.03; 118 (11): ( DOI )
-
Nori Nakai, Keisuke Sato, Tomomi Tani, Kenta Saito, Fumiya Sato, and Sumio Terada. Genetically encoded orientation probes for F-actin for fluorescence polarization microscopy Microscopy. 2019; ( DOI )
-
Kenta Saito, Masafumi Nakano,Takeharu Nagai. Luminescence Imaging: (a) Multicolor Visualization of Ca2+ Dynamics in Different Cellular Compartments and (b) Video-Rate Tumor Detection in a Freely Moving Mouse. Meth. Mol. Biol.. 2016.01; 1461 289-297. ( DOI )
-
Masahito Yamanaka, Kenta Saito, Nicholas I Smith, Yoshiyuki Arai, Kumiko Uegaki, Yasuo Yonemaru, Kentaro Mochizuki, Satoshi Kawata, Takeharu Nagai, Katsumasa Fujita. Visible-wavelength two-photon excitation microscopy for fluorescent protein imaging. J Biomed Opt. 2015.10; 20 (10): 101202. ( PubMed, DOI )
-
Kenta Saito, Takeharu Nagai. Recent progress in luminescent proteins development. Curr Opin Chem Biol. 2015.08; 27 46-51. ( PubMed, DOI )
-
Akira Takai, Masahiro Nakano, Kenta Saito, Remi Haruno, Tomonobu M Watanabe, Tatsuya Ohyanagi, Takashi Jin, Yasushi Okada, Takeharu Nagai. Expanded palette of Nano-lanterns for real-time multicolor luminescence imaging. Proc. Natl. Acad. Sci. U.S.A.. 2015.04; 112 (14): 4352-4356. ( PubMed, DOI )
-
Takeharu Nagai, Kazuki Horikawa, Kenta Saito, Tomoki Matsuda. Genetically encoded Ca2+ indicators; expanded affinity range, color hue and compatibility with optogenetics. Front Mol Neurosci. 2014.11; 7 90. ( PubMed, DOI )
-
Masahito Yamanaka, Kenta Saito, Nicholas I Smith, Satoshi Kawata, Takeharu Nagai, Katsumasa Fujita. Saturated excitation of fluorescent proteins for subdiffraction-limited imaging of living cells in three dimensions Interface focus: a theme supplement of Journal of the Royal Society interface. 2013.10; 3 (5): 20130007.
-
Tomoki Matsuda, Kazuki Horikawa, Kenta Saito, Takeharu Nagai. Highlighted Ca2+ imaging with a genetically encoded 'caged' indicator Scientific Reports. 2013.03; 3 1398.
-
永井健治、齊藤健太、初谷紀幸. 化学発光タンパク質の高輝度化とバイオイメージングへの展開 顕微鏡. 2013; 48 1-3.
-
K. Saito, Y. Higuchi, Y. Arai, T. Nagai. Video-rate imaging of luminescent tumour cells in freely moving unshaved mice. Protoc. Exch.. 2013; ( DOI )
-
Kenta Saito, Y-F Chang, Kazuki Horikawa, Noriyuki Hatsugai, Yuriko Higuchi, Mitsuru Hashida, Yu Yoshida, Tomoki Matsuda, Yoshiyuki Arai, Takeharu Nagai. Luminescent proteins for high-speed single-cell and whole-body imaging. Nature communications. 2012.12; 3 1262. ( PubMed, DOI )
-
Saito K, Arai Y, Zhang J, Kobayashi K, Tani T, Nagai T. Conjugation of both on-axis and off-axis light in Nipkow disk confocal microscope to increase availability of incoherent light source. Cell structure and function. 2011; 36 237-246. ( PubMed )
-
Sadamoto H, Saito K, Muto H, Kinjo M, Ito E. Direct observation of dimerization between different CREB1 isoforms in a living cell. PloS one. 2011; 6 e20285. ( PubMed, DOI )
-
Saito K, Hatsugai N, Horikawa K, Kobayashi K, Matsu-Ura T, Mikoshiba K, Nagai T. Auto-luminescent genetically-encoded ratiometric indicator for real-time Ca2+ imaging at the single cell level. PloS one. 2010.04; 5 e9935. ( PubMed, DOI )
-
Tomosugi W, Matsuda T, Tani T, Nemoto T, Kotera I, Saito K, Horikawa K, Nagai T. An ultramarine fluorescent protein with increased photostability and pH insensitivity. Nature methods. 2009.05; 6 351-353. ( PubMed, DOI )
-
Yamamoto T, Kumagai A, Saito K, Nagai T. Two-photon excitation behavior of thiophene-based oligomers and a polymer. Journal of nanoscience and nanotechnology. 2009.01; 9 670-672. ( PubMed )
-
Imamura, H. and Nhat, K. P. H. and Togawa, H. and Saito, K. and Iino, R. and Kato-Yamada, Y. and Nagai, T. and Noji, H.. Visualization of ATP levels inside single living cells with fluorescence resonance energy transfer-based genetically encoded indicators Proc. Natl. Acad. Sci. U.S.A.. 2009; 106 (37): 15651-15656.
-
Saito K, Kobayashi K, Tani T, Nagai T. A mercury arc lamp-based multi-color confocal real time imaging system for cellular structure and function. Cell structure and function. 2008; 33 133-141. ( PubMed )
-
Oguma, T. and Hosaka, S. and Katayama, T. and Matsuda, T. and Saito, K. and Nagai, T. and Minami, M.. Effects of astrocyte morphological changes on brain cell function Yakugaku Zasshi-Journal of the Pharmaceutical Society of Japan. 2008; 128 192-195.
-
福岡 創, 齋藤 健太, 永井 健治, 本間 道夫, 石島 秋彦. 3P179 イオン駆動回転モーター構成素子のGFPによる一分子標識(分子モーター,ポスター発表,第45回日本生物物理学会年会) 生物物理. 2007.11; 47 (1):
-
今村 博臣, Kim Huynh Nhat Phuong, 齊藤 健太, 飯野 亮太, 山田 康之, 永井 健治, 野地 博行. 3P326 細胞内ATPを蛍光で可視化する(バイオイメージング,ポスター発表,第45回日本生物物理学会年会) 生物物理. 2007.11; 47 (1):
-
谷 知己, 齋藤 健太, 永井 健治. 3P323 リガンド結合にともなう神経成長因子受容体TrkAの構造ダイナミクスを可視化する試み(バイオイメージング,ポスター発表,第45回日本生物物理学会年会) 生物物理. 2007.11; 47 (1):
-
友杉 亘, 松田 知己, 小寺 一平, 齋藤 健太, 永井 健治. 3P305 群青色蛍光蛋白質の開発(バイオイメージング,ポスター発表,第45回日本生物物理学会年会) 生物物理. 2007.11; 47 (1):
-
Ohsugi Y, Saito K, Tamura M, Kinjo M. Lateral mobility of membrane-binding proteins in living cells measured by total internal reflection fluorescence correlation spectroscopy. Biophysical journal. 2006.11; 91 3456-3464. ( PubMed, DOI )
-
Pack C, Saito K, Tamura M, Kinjo M. Microenvironment and effect of energy depletion in the nucleus analyzed by mobility of multiple oligomeric EGFPs. Biophysical journal. 2006.11; 91 3921-3936. ( PubMed, DOI )
-
Kogure T, Karasawa S, Araki T, Saito K, Kinjo M, Miyawaki A. A fluorescent variant of a protein from the stony coral Montipora facilitates dual-color single-laser fluorescence cross-correlation spectroscopy. Nature biotechnology. 2006.05; 24 577-581. ( PubMed, DOI )
-
Lakowicz, Joseph R.. Chapter 13 Energy Transfer. In: PRINCIPLES OF FLUORESCENCE SPECTROSCOPY 2006;
-
Ohsugi, Y. and Saito, K. and Tamura, M. and Kinjo, M.. Development of a novel monitoring system for cell activity based on visualization of chromosome dynamics Cell Structure and Function. 2005; 30 117.
-
Watanabe K, Saito K, Kinjo M, Matsuda T, Tamura M, Kon S, Miyazaki T, Uede T. Molecular dynamics of STAT3 on IL-6 signaling pathway in living cells. Biochemical and biophysical research communications. 2004.11; 324 1264-1273. ( PubMed, DOI )
-
Saito K, Wada I, Tamura M, Kinjo M. Direct detection of caspase-3 activation in single live cells by cross-correlation analysis. Biochemical and biophysical research communications. 2004.11; 324 849-854. ( PubMed, DOI )
-
Földes-Papp Z, Costa JM, Demel U, Tilz GP, Kinjo M, Saito K, Kii H, Takagi T, Tamura M, Thyberg P, Birch-Hirschfeld E. Specifically associated PCR products probed by coincident detection of two-color cross-correlated fluorescence intensities in human gene polymorphisms of methylene tetrahydrofolate reductase at site C677T: a novel measurement approach without follow-up ma Experimental and molecular pathology. 2004.06; 76 212-218. ( PubMed, DOI )
-
Sadamoto, H. and Wagatsuma, A. and Saito, K. and Kinjo, M. and Ito, E.. CREB isoforms in central nervous system of pond snail Lymnaea stagnalis Zoological Science. 2004; 21 (12): 1317.
-
Saito K, Ito E, Takakuwa Y, Tamura M, Kinjo M. In situ observation of mobility and anchoring of PKCbetaI in plasma membrane. FEBS letters. 2003.04; 541 126-131. ( PubMed )
-
Földes-Papp Z, Kinjo M, Saito K, Kii H, Takagi T, Tamura M, Costa JM, Birch-Hirschfeld E, Demel U, Thyberg P, Tilz GP. C677T single nucleotide polymorphisms of the human methylene tetrahydrofolate reductase and specific identification : a novel strategy using two-color cross-correlation fluorescence spectroscopy. Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology. 2003; 7 99-111. ( PubMed )
-
Muto, T. and Saito, K. and Tamura, M. and Kinjo, M.. Microenvironment analysis in squid axons using fluorescence correlation spectroscopy and laser scanning microscopy Acta Histochemica Et Cytochemica. 2002; 35 (2): 87-91.
Conference Activities & Talks 【 display / non-display 】
-
Keisuke Sato, Nori Nakai-Kadowaki, Ayana Sugizaki, Kazuyoshi Chiba, Kenta Saito, Masahiko Kawagishi, Yuri Tomabechi, Shalin B. Mehta, Hirokazu Ishii, Naoki Sakai, Hiromasa Ka, Mikako Shirouzu, Tomomi Tani, Sumio Terada. Development of POLArIS, a versatile probe for multi-color/multi-target orientation imaging in living cells. Cell Bio 2022 2022.12.04 Washington, DC
-
Nori Nakai, Keisuke Sato, Tomomi Tani, Masahiko Kawagishi, Hiromasa Ka, Kenta Saito, Sumio Terada. EXPANDED REPERTOIRE OF POLARIS, A VERSATILE FLUORESCENT PROBE FOR MOLECULAR ORIENTATION. Biophysical Society 66th Annual Meeting 2022.02.23 USA
-
佐藤啓介, 杉﨑 綾奈, 齊藤 健太, Shalin B. Mehta, 白水 美香子, 谷 知己, 寺田 純雄. F-actin特異的分子配向プローブPOLArISactの開発と評価. 第126回日本解剖学会総会・全国学術集会 2021.03.29 オンライン開催