論文・総説 - 加納　嘉人

21. Matsudera S, Kano Y, Ikeda S. ASO Author Reflections: Impact of Liquid Biopsy Using Plasma Cell-Free DNA in Solid Tumors in Japan. Annals of surgical oncology. 2021.03; ( PubMed, DOI )

22. Matsudera S, Kano Y, Aoyagi Y, Tohyama K, Takahashi K, Kumaki Y, Mitsumura T, Kimura K, Onishi I, Takemoto A, Ban D, Ono H, Kudo A, Oshima N, Ogino K, Watanabe S, Tani Y, Yamaguchi T, Nakajima M, Morita S, Yamaguchi S, Takagi M, Ishikawa T, Nakagawa T, Okamoto K, Uetake H, Tanabe M, Miyake S, Tsuchioka T, Kojima K, Ikeda S. A Pilot Study Analyzing the Clinical Utility of Comprehensive Genomic Profiling Using Plasma Cell-Free DNA for Solid Tumor Patients in Japan (PROFILE Study). Annals of surgical oncology. 2021.03; ( PubMed, DOI )

23. Kano Yoshihito, Marshall Christopher, Ikura Mitsuhiko. Evasion of KRAS Q61H regulation by tyrosine phosphorylation renders cancer cells resistant to SHP2 inhibitors CANCER SCIENCE. 2021.02; 112 171.

24. Liotti F, Kumar N, Prevete N, Marotta M, Sorriento D, Ieranò C, Ronchi A, Marino FZ, Moretti S, Colella R, Puxeddu E, Paladino S, Kano Y, Ohh M, Scala S, Melillo RM. PD-1 blockade delays tumor growth by inhibiting an intrinsic SHP2/Ras/MAPK signalling in thyroid cancer cells. Journal of experimental & clinical cancer research : CR. 2021.01; 40 (1): 22. ( PubMed, DOI )

25. Katsukura N, Watanabe S, Shirasaki T, Hibiya S, Kano Y, Akahoshi K, Tanabe M, Kirimura S, Akashi T, Kitagawa M, Okamoto R, Watanabe M, Tsuchiya K. Intestinal phenotype is maintained by Atoh1 in the cancer region of intraductal papillary mucinous neoplasm. Cancer science. 2020.12; ( PubMed, DOI )

26. Matsudera Shotaro, Kano Yoshihito, Aoyagi Yasuko, Tohyama Kohki, Ogino Kei, Okamoto Kentaro, Tsuchioka Takashi, Kojima Kazuyuki, Takagi Masatoshi, Ikeda Sadakatsu. Clinical Utility of Comprehensive Genomic Profiling for Pediatric and AYA Solid Tumor Patients PEDIATRIC BLOOD & CANCER. 2020.12; 67

27. Aoyagi Yasuko, Kano Yoshihito, Ban Daisuke, Tokunaga Masanori, Nakajima Yasuaki, Uetake Hiroyuki, Tanabe Minoru, Miyake Satoshi, Kinugasa Yusuke, Ikeda Sadakatsu. Future perspectives of cancer genomic medicine in gastroenterological surgery　Clinical utility of multiple genomic testing in patients with advanced solid tumor(和訳中) 日本消化器外科学会総会. 2020.12; 75回 WS14-3. ( 医中誌 )

28. 加納 嘉人, Gebregiworgis Teklab, Marshall Christopher, Ikura Mitsuhiko, Ohh Michael. ドライバー遺伝子異常陽性がん治療の新たな局面　KRASQ61H変異によるSHP2阻害剤耐性機構解析 日本癌学会総会記事. 2020.10; 79回 IS1-3. ( 医中誌 )

29. Matsudera Shotaro, Kano Yoshihito, Aoyagi Yasuko, Tohyama Kohki, Ogino Kei, Okamoto Kentaro, Tsuchioka Takashi, Kojima Kazuyuki, Takagi Masatoshi, Ikeda Sadakatsu. 小児・AYA世代の進行再発固形がん患者におけるがん遺伝子パネル検査の臨床的有用性の検討(Clinical utility of comprehensive genomic profiling for pediatric and AYA solid tumor patients) 日本小児血液・がん学会雑誌. 2020.10; 57 (4): 243. ( 医中誌 )

30. 松寺 翔太郎, 加納 嘉人, 青柳 康子, 遠山 皓基, 木村 浩一朗, 大西 威一郎, 竹本 暁, 荻野 恵, 岡本 健太郎, 植竹 宏之, 田邉 稔, 三宅 智, 土岡 丘, 小嶋 一幸, 池田 貞勝. Liquid biopsyが変えるがん治療　がんゲノム医療におけるリキッドバイオプシーの臨床的有用性の検討 日本癌治療学会学術集会抄録集. 2020.10; 58回 WS12-4. ( 医中誌 )

31. Ivette Valencia-Sama, Yagnesh Ladumor, Lynn Kee, Teresa Adderley, Gabriella Christopher, Claire M Robinson, Yoshihito Kano, Michael Ohh, Meredith S Irwin. Status determines sensitivity to SHP2 inhibitor combination therapies targeting the RAS-MAPK pathway in neuroblastoma. Cancer Res. 2020.08; 80 (16): 3413-3423. ( PubMed, DOI )

32. Takahashi Kenta, Gen Yasuyuki, Tanimoto Kousuke, Kudo Atsushi, Oshima Noriko, Ban Daisuke, Takemoto Akira, Onishi Iichiro, Kumaki Yuichi, Yokobori Junko, Takamine Eriko, Kano Yoshihito, Miyake Satoshi, Miyasaka Naoyuki, Tanabe Minoru, Inazawa Johji, Ikeda Sadakatsu. Clinical impact of hemizygous deletion detection and panel-size in comprehensive genomic profiling. JOURNAL OF CLINICAL ONCOLOGY. 2020.05; 38 (15):

33. Kitaoka Y, Watanabe D, Nonaka Y, Yagishita K, Kano Y, Hoshino D. Effects of clenbuterol administration on mitochondrial morphology and its regulatory proteins in rat skeletal muscle. Physiological reports. 2019.10; 7 (19): e14266. ( PubMed, DOI )

34. Claire M Robinson, Betty P K Poon, Yoshihito Kano, Fred G Pluthero, Walter H A Kahr, Michael Ohh. A hypoxia-inducible HIF1-GAL3ST1-sulfatide axis enhances ccRCC immune evasion via increased tumor cell-platelet binding. Mol Cancer Res. 2019.08; 17 (11): 2306-2317. ( PubMed, DOI )

35. Keita Fukushima, Kiichiro Tsuchiya, Yoshihito Kano, Nobukatsu Horita, Shuji Hibiya, Ryohei Hayashi, Keisuke Kitagaki, Mariko Negi, Eisaku Itoh, Takumi Akashi, Yoshinobu Eishi, Shigeru Oshima, Takashi Nagaishi, Ryuichi Okamoto, Tetsuya Nakamura, Mamoru Watanabe. Atonal homolog 1 protein stabilized by tumor necrosis factor α induces high malignant potential in colon cancer cell line. Cancer Science. 2015.08; 106 (8): 1000-1007. ( PubMed, DOI )

36. Fukushima Keita, Tsuchiya Kiichiro, Kano Yoshihito, Horita Nobukatsu, Hibiya Shuji, Hayashi Ryohei, Kitagaki Keisuke, Negi Mariko, Itoh Eisaku, Akashi Takumi, Eishi Yoshinobu, Oshima Shigeru, Nagaishi Takashi, Okamoto Ryuichi, Nakamura Tetsuya, Watanabe Mamoru. 腫瘍壊死因子αにより安定化するatonal homolog 1タンパク質は大腸癌細胞株において高悪性度を引き起こす(Atonal homolog 1 protein stabilized by tumor necrosis factor α induces high malignant potential in colon cancer cell line) Cancer Science. 2015.08; 106 (8): 1000-1007. ( 医中誌 )

37. Nobukatsu Horita, Kiichiro Tsuchiya, Ryohei Hayashi, Keita Fukushima, Shuji Hibiya, Masayoshi Fukuda, Yoshihito Kano, Tomohiro Mizutani, Yasuhiro Nemoto, Shiro Yui, Ryuichi Okamoto, Tetsuya Nakamura, Mamoru Watanabe. Fluorescent labelling of intestinal epithelial cells reveals independent long-lived intestinal stem cells in a crypt. Biochem. Biophys. Res. Commun.. 2014.11; 454 (4): 493-499. ( PubMed, DOI )

38. Yoshihito Kano, Sei Kakinuma, Fumio Goto, Seishin Azuma, Yuki Nishimura-Sakurai, Yasuhiro Itsui, Mina Nakagawa, Atsushi Kudo, Minoru Tanabe, Susumu Kirimura, Tomonori Amano, Takashi Ito, Takumi Akashi, Yasuhiro Asahina, Mamoru Watanabe. Primary hepatic neuroendocrine carcinoma with a cholangiocellular carcinoma component in one nodule. Clin J Gastroenterol. 2014.10; 7 (5): 449-454. ( PubMed, DOI )

39. Kano Yoshihito, Kakinuma Sei, Goto Fumio, Azuma Seishin, Nishimura-Sakurai Yuki, Itsui Yasuhiro, Nakagawa Mina, Kudo Atsushi, Tanabe Minoru, Kirimura Susumu, Amano Tomonori, Ito Takashi, Akashi Takumi, Asahina Yasuhiro, Watanabe Mamoru. 結節の一つに胆管細胞癌部分を合併した原発性肝神経内分泌癌(Primary hepatic neuroendocrine carcinoma with a cholangiocellular carcinoma component in one nodule) Clinical Journal of Gastroenterology. 2014.10; 7 (5): 449-454. ( 医中誌 )

40. Severa Bunda, Pardeep Heir, Tharan Srikumar, Jonathan D Cook, Kelly Burrell, Yoshihito Kano, Jeffrey E Lee, Gelareh Zadeh, Brian Raught, Michael Ohh. Src promotes GTPase activity of Ras via tyrosine 32 phosphorylation. Proc. Natl. Acad. Sci. U.S.A.. 2014.09; 111 (36): E3785-E3794. ( PubMed, DOI )