Personnel Information

写真a

KAIDA Atsushi


Job title

Assistant Professor

Birth date

1983

Mail Address

The inquiry by e-mail is 《here

Graduating School 【 display / non-display

  • Tokyo Medical and Dental University, Faculty of Dentistry, 2008.03, Graduated

Graduate School 【 display / non-display

  • Tokyo Medical and Dental University, Doctor's Course, 2012.03, Completed

Campus Career 【 display / non-display

  • 2013.09
    -
    2018.03
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Oral Health Sciences, Oral Radiation Oncology, Assistant Professor
  • 2018.04
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Oral Health Sciences, Oral Radiation Oncology, Assistant Professor

External Career 【 display / non-display

  • 2008.10
    -
    2009.03
    , Trainee Resident of Dentistry
  • 2019.04
    -
    2021.03
    University of Kansas Medical Center, Department of Cancer Biology, Postdoctoral fellow

Qualification Acquired 【 display / non-display

  • Dentist

 

Published Papers & Misc 【 display / non-display

  1. Atsushi Kaida, Tomoo Iwakuma. Regulation of p53 and Cancer Signaling by Heat Shock Protein 40/J-Domain Protein Family Members International Journal of Molecular Sciences. 2021.12; 22 (24): ( DOI )

  2. Yoshimura Ryo-ichi, Toda Kazuma, Watanabe Hiroshi, Kaida Atsushi, Harada Hiroyuki, Asakage Takahiro, Miura Masahiko. Efficacy and Safety of Induction Chemotherapy and/or External Beam Radiotherapy Followed by Brachytherapy in Patients With Tongue Cancer ANTICANCER RESEARCH. 2021.12; 41 (12): 6259-6266. ( PubMed, DOI )

  3. Kaida Atsushi, Yamamoto Satomi, Parrales Alejandro, Young Eric D., Ranjan Atul, Alalem Mohamed A., Morita Kei-ichi, Oikawa Yu, Harada Hiroyuki, Ikeda Tohru, Thomas Sufi M., Diaz Francisco J., Iwakuma Tomoo. DNAJA1 promotes cancer metastasis through interaction with mutant p53 Oncogene. 2021.08; 40 (31): 5013-5025. ( PubMed, DOI )

  4. Kohei Okuyama, Keiji Suzuki, Tomofumi Naruse, Hiroki Tsuchihashi, Souichi Yanamoto, Atsushi Kaida, Masahiko Miura, Masahiro Umeda, Shunichi Yamashita. Prolonged cetuximab treatment promotes p27 Kip1-mediated G1 arrest and autophagy in head and neck squamous cell carcinoma. Sci Rep. 2021.03; 11 (1): 5259. ( PubMed, DOI )

  5. Hiroaki Shimono, Atsushi Kaida, Hisao Homma, Hitomi Nojima, Yusuke Onozato, Hiroyuki Harada, Masahiko Miura. Fluctuation in radioresponse of HeLa cells during the cell cycle evaluated based on micronucleus frequency. Sci Rep. 2020.11; 10 (1): 20873. ( PubMed, DOI )

  6. Nojima Hitomi, Homma Hisao, Onozato Yusuke, Kaida Atsushi, Harada Hiroyuki, Miura Masahiko. Differential properties of mitosis-associated events following CHK1 and WEE1 inhibitor treatments in human tongue carcinoma cells EXPERIMENTAL CELL RESEARCH. 2020.01; 386 (2): 111720. ( PubMed, DOI )

  7. Hisao Honma, Hitomi Nojima, Atsusi Kaida, Masahiko Miura. Induction of endomitosis-like event in HeLa cells following CHK1 inhibitor treatment Biochem Biophys Res Commun. 2019.12; 520 (2): 492-497. ( PubMed )

  8. Goto T, Homma H, Kaida A, Miura M. WEE1 inhibition enhances sensitivity to hypoxia/reoxygenation in HeLa cells. Journal of radiation research. 2019.09; 60 (5): 714-718. ( PubMed, DOI )

  9. 三浦雅彦, 戒田篤志. 放射線照射後の腫瘍細胞における再分布動態の可視化とその臨床的意義 放射線生物研究. 2018.12; 53 (4): 265-279.

  10. Nisha Gowri Manila, Atsushi Kaida, Ken-Ichi Nakahama, Masahiko Miura. Insulin-like growth factor I receptor regulates the radiation-induced G2/M checkpoint in HeLa cells. Biochem. Biophys. Res. Commun.. 2018.08; 503 (4): 2977-2983. ( PubMed, DOI )

  11. Okuyama Kohei, Yamashiro Masashi, Kaida Atsushi, Kawamata Aya, Mizutani Miho, Michi Yasuyuki, Uzawa Narikazu, Yano Tomoyuki, Tohyama Rei, Yamaguchi Satoshi. Does a Vascularized Fibula Free Bone Grafted Immediately After Hemimandibulectomy in a Child Grow or Relapse During Adolescence? JOURNAL OF CRANIOFACIAL SURGERY. 2018.07; 29 (5): E444-E449. ( PubMed, DOI )

  12. Sirimanas Jiaranuchart, Atsushi Kaida, Yusuke Onozato, Hiroyuki Harada, Masahiko Miura. DNA damage response following X-irradiation in oral cancer cell lines HSC3 and HSC4. Arch. Oral Biol.. 2018.03; 90 1-8. ( PubMed, DOI )

  13. Atsushi Kaida, Hiroshi Watanabe, Kazuma Toda, Keiko Yuasa-Nakagawa, Ryoichi Yoshimura, Masahiko Miura. Effects of dose rate on early and late complications in low dose rate brachytherapy for mobile tongue carcinoma using Ir-192 sources. Oral Radiol. 2017.09; 33 (3): 187-192. ( DOI )

  14. Atsushi Oba, Shu Shimada, Yoshimitsu Akiyama, Taketo Nishikawaji, Kaoru Mogushi, Hiromitsu Ito, Satoshi Matsumura, Arihiro Aihara, Yusuke Mitsunori, Daisuke Ban, Takanori Ochiai, Atsushi Kudo, Hiroshi Asahara, Atsushi Kaida, Masahiko Miura, Minoru Tanabe, Shinji Tanaka. ARID2 modulates DNA damage response in human hepatocellular carcinoma cells. J. Hepatol.. 2017.05; 66 (5): 942-951. ( PubMed, DOI )

  15. Yusuke Onozato, Atsushi Kaida, Hiroyuki Harada, Masahiko Miura. Radiosensitivity of quiescent and proliferating cells grown as multicellular tumor spheroids. Cancer Sci.. 2017.04; 108 (4): 704-712. ( PubMed, DOI )

  16. Y Ozaki, H Watanabe, A Kaida, M Miura, K Nakagawa, K Toda, R Yoshimura, Y Sumi, T Kurabayashi. Estimation of whole-body radiation exposure from brachytherapy for oral cancer using a Monte Carlo simulation. J. Radiat. Res.. 2017.02; 24 1-6. ( PubMed, DOI )

  17. Nisha Gowri Manila, Atsushi Kaida, Masahiko Miura. Kinetic analysis of radiation-induced cell-cycle alterations in HeLa Cells expressing fluorescent ubiquitination-based cell cycle indicator (Fucci). Radiat Environ Med. 2016.08; 5 (2): 16-21.

  18. Taito Asahina, Atsushi Kaida, Tatsuaki Goto, Ryo-Ichi Yoshimura, Keisuke Sasai, Masahiko Miura. Temporo-spatial cell-cycle kinetics in HeLa cells irradiated by Ir-192 high dose-rate remote afterloading system (HDR-RALS). Radiat Oncol. 2016.07; 11 99. ( PubMed, DOI )

  19. Tatsuaki Goto, Atsushi Kaida, Masahiko Miura. Visualizing cell-cycle kinetics after hypoxia/reoxygenation in HeLa cells expressing fluorescent ubiquitination-based cell cycle indicator (Fucci). Exp. Cell Res.. 2015.12; 339 (2): 389-396. ( PubMed, DOI )

  20. Kohei Okuyama, Atsushi Kaida, Yoshiki Hayashi, Yoshio Hayashi, Kiyoshi Harada, Masahiko Miura. KPU-300, a Novel Benzophenone-Diketopiperazine-Type Anti-Microtubule Agent with a 2-Pyridyl Structure, Is a Potent Radiosensitizer That Synchronizes the Cell Cycle in Early M Phase. PLoS ONE. 2015.12; 10 (12): e0145995. ( PubMed, DOI )

  21. Atsushi Kaida, Masahiko Miura. Unusual prolongation of radiation-induced G2 arrest in tumor xenografts derived from HeLa cells. Cancer Sci.. 2015.10; 106 (10): 1370-1376. ( PubMed, DOI )

  22. Eri Tsuchida, Atsushi Kaida, Endrawan Pratama, Masa-Aki Ikeda, Keiji Suzuki, Kiyoshi Harada, Masahiko Miura. Effect of X-Irradiation at Different Stages in the Cell Cycle on Individual Cell-Based Kinetics in an Asynchronous Cell Population. PLoS ONE. 2015.06; 10 (6): e0128090. ( PubMed, DOI )

  23. Chisato Yamada, Atsushi Kaida, Kohei Okuyama, Kiyoshi Harada, Masahiko Miura. Effects of Chk1 inhibitor or paclitaxel on cisplatin-induced cell-cycle kinetics and survival in parental and cisplatin-resistant HeLa cells expressing fluorescent ubiquitination based cell cycle indicator (Fucci). Integr Cancer Sci Therap. 2015; 2 87-92.

  24. Kamrun Nahar, Tatsuaki Goto, Atsushi Kaida, Shifumi Deguchi, Masahiko Miura. Effects of Chk1 inhibition on the temporal duration of radiation-induced G2 arrest in HeLa cells. Journal of Radiation Research. 2014.06; 55 (5): 1021-1027. ( PubMed, DOI )

  25. Atsushi Kaida, Masahiko Miura. Visualizing the effect of tumor microenvironments on radiation-induced cell kinetics in multicellular spheroids consisting of HeLa cells. Biochemical and Biophysical Research Communications. 2013.10; 439 (4): 453-458. ( PubMed, DOI )

  26. Asumi Honda-Uezono, Atsushi Kaida, Yasuyuki Michi, Kiyoshi Harada, Yoshiki Hayashi, Yoshio Hayashi, Masahiko Miura. Unusual expression of red fluorescence at M phase induced by anti-microtubule agents in HeLa cells expressing the fluorescent ubiquitination-based cell cycle indicator (Fucci). Biochemical and Biophysical Research Communications. 2012.11; 428 (2): 224-229. ( PubMed, DOI )

  27. Ryo-Ichi Yoshimura, Hitoshi Shibuya, Keiji Hayashi, Keiko Nakagawa, Kazuma Toda, Hiroshi Watanabe, Atsushi Kaida, Masahiko Miur. Repeat brachytherapy for patients with residual or recurrent tumors of oral cavity. Int. J. Radiat. Oncol. Biol. Phys.. 2012.07; 83 (4): 1198-1204. ( PubMed, DOI )

  28. Atsushi Kaida, Masahiko Miura. Differential dependence on oxygen tension during the maturation process between monomeric Kusabira Orange 2 and monomeric Azami Green expressed in HeLa cells. Biochemical and Biophysical Research Communications. 2012.05; 421 (4): 855-859. ( PubMed, DOI )

  29. Atsushi Kaida, Masahiko Miura. Visualizing the effect of hypoxia on fluorescence kinetics in living HeLa cells using the fluorescent ubiquitination-based cell cycle indicator (Fucci). Exp. Cell Res.. 2012.02; 318 (3): 288-297. ( PubMed, DOI )

  30. Motoshi Nakayama, Atsushi Kaida, Shifumi Deguchi, Kengo Sakaguchi, Masahiko Miura. Radiosensitivity of early and late M-phase HeLa cells isolated by a combination of fluorescent ubiquitination-based cell cycle indicator (Fucci) and mitotic shake-off. Radiat. Res.. 2011.09; 176 (3): 407-411. ( PubMed )

  31. Atsushi Kaida, Naoki Sawai, Kengo Sakaguchi, Masahiko Miura. Fluorescence kinetics in HeLa cells after treatment with cell cycle arrest inducers visualized with Fucci (fluorescent ubiquitination-based cell cycle indicator). Cell Biol. Int.. 2011.04; 35 (4): 359-363. ( PubMed, DOI )

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Books etc 【 display / non-display

  1. Atsushi Kaida, Masahiko Miura. Cell Cycle Oscillators. Springer Nature, 2021.06 Visualization of Radiation-Induced Cell Cycle Kinetics with a Fluorescent Ubiquitination-Based Cell Cycle Indicator (Fucci)

Conference Activities & Talks 【 display / non-display

  1. Atsushi Kaida, Satomi Yamamoto, Atul Ranjan, Alejandro Parrales, Mohamed Alalem, Tomoo Iwakuma. DNAJA1 promotes cancer metastasis through the interaction with misfolded mutant p53. 2nd International Conference "Cancer Metastasis" 2021.12.15 Web開催

  2. Katarzyna A. Inoue, Kazuki Takahashi, Sakakitani Shintaro, Daizo Koinuma, Akinari Sugauchi, Maki Saito, Atsushi Kaida, Yasuhiro Yoshimatsu, Toshihiro Uchihashi, Masahiko Miura, Kohei Miyazono, Tetsuro Watabe. Activation of epithelial-mesenchymal transition program in oral cancer cells under TGF-β-induced cell cycle arrest. TGF-β Superfamily Conference: Signaling in Development and Disease (FASEB) 2021.07.20

  3. Katarzyna A. Inoue, Kazuki Takahashi, Sakakitani Shintaro, Daizo Koinuma, Akinari Sugauchi, Maki Saito, Atsushi Kaida, Yasuhiro Yoshimatsu, Toshihiro Uchihashi, Masahiko Miura, Kohei Miyazono, Tetsuro Watabe. Activation of epithelial-mesenchymal transition program in oral cancer cells under TGF-β-induced cell cycle arrest. TGF-β Superfamily Conference: Signaling in Development and Disease (FASEB) 2021.07.20

  4. 高橋和樹, 井上カタジナアンナ, 戒田篤志, 高橋恵生, 久保田晋平, 須河内昭成, 内橋俊大, 田中晋, 古郷幹彦, 三浦雅彦, 宮園浩平, 渡部徹郎. TGF-βにより細胞周期が停止した口腔扁平上皮がん細胞の運動能ならびに転移能は亢進する. 第78回日本癌学術総会 2019.09.28 京都市

  5. Kazuki Takahashi, Katarzyna A. Inoue, Yasuhiro Yoshimatsu, Atsushi Kaida, Kei Takahashi, Shimpei Kubota, Akinari Sugauchi, Toshihiro Uchihashi, Susumu Tanaka, Mikihiko Kogo, Masahiko Miura, Kohei Miyazono and Tetsuro Watabe. Regulatory role of transforming growth factor-β signals in the migration and cell cycle of oral squamous carcinoma cells. Keystone Symposia; Cancer Metastasis: The role of metabolism, immunity and microenvironment 2019.03.17 Florence, Italy

  6. Kazuki Takahashi, Katarzyna A. Inoue, Yasuhiro Yoshimatsu, Atsushi Kaida, Kei Takahashi, Shimpei Kubota, Akinari Sugauchi, Toshihiro Uchihashi, Susumu Tanaka, Mikihiko Kogo, Masahiko Miura, Kohei Miyazono and Tetsuro Watabe. TGF-β-induced cell cycle arrest is associated with increased migration and metastasis of oral squamous carcinoma cells. AACR-JCA Joint Conference 2019.02.09 Maui, USA

  7. Atsushi Kaida, Yusuke Onozato, Masahiko Miura. Determining radiosensitivity of quiescent and proliferating tumor cells irradiated under different tumor microenvironments. 33th International Symposium of Radiation Biology Center, Kyoto University 2017.12.05 Kyoto city

  8. Nisha Gowri Manila, Atsushi Kaida, Masahiko Miura. Insulin-like growth factor I receptor (IGF-IR) regulates radiation-induced G2/M checkpoint by controlling Chk1 localization in HeLa cells. TMDU Intractable Disease(Cancer) Unit Workshops for Young Researchers 2017.11.06 Tokyo

  9. Atsushi KAIDA. Effects of tumor microenvironments on cell cycle kinetics following X-irradiation. TMDU Instractable Disease (Cancer) Unit Overseas training Seminar Young Researchers (Soo chow Uniiversity) 2017.02.22 Soo chow, China

  10. Nisha Gowri Manila, Atsushi Kaida, Masahiko Miura. IGF-IR, but not EGFR, regulates DNA damage response (DDR) in HeLa cells following irradiation. ESMO Asia 2016 Congress 2016.12.17 Singapore

  11. Yusuke Onozato, Atsushi Kaida, Hiroyuki Harada, Masahiko Miura. Radiosenstivity of proliferating or quiescent human tongue carcinoma cells grown in multicellular spheroids. The 61th congress of the Japanese Society of Oral and Maxillofacial Surgeons 2016.11.25 Chiba city

  12. 小野里祐佑, 戒田篤志, 原田浩之, 三浦雅彦. Fucciを導入した口腔扁平上皮癌細胞における放射線照射後の細胞周期動態解析. 第34回日本口腔腫瘍学会総会・学術大会 2016.01.21 横浜市

  13. Nisha Gowri Manila, Atsushi Kaida, Masahiko Miura. Effect of IGF-IR-inhibition on the radiation –induced cell kinetics and DNA repair. 80th Anual Meeting of the Stomatological Society 2015.12.26 Tokyo

  14. Nisha Gowri Manila, Atsushi Kaida, Masahiko Miura. IGF-1 receptor influences radeation-indeced G2 arrest in HeLa cells expressing fluorescent ubiquitination-based cell cycle indicator (Fucci). ISAJ 6th Symposium on Recent Advances and Technology 2015.12.04 Tokyo

  15. Atsushi Kaida, Masahiko Miura. Visualizing the effects of tumor microenviroments on cell cycle kinetics in HeLa cells following X-irradiation. 15th International Congress of Radiation Research 2015.05.28 Kyoto

  16. Atsushi Kaida, Masahiko Miura. Radiation-induced Cell Cycle Kinetics in Vitro and in Vivo as Visualized by a Fluorescent Ubiquitination-based Cell Cycle Indicator (Fucci). The 16th Takeda Science Foundation Symposium on Bioscience 2010.12.01 Tokyo

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