Graduating School 【 display / non-display 】

Graduating School 【 display / non-display 】

• Tokyo University of Science, Faculty of Science and Engineering, 2004.03, Graduated

Graduate School 【 display / non-display 】

Graduate School 【 display / non-display 】

• Kyoto University, Graduate School, Division of Life Science, Master's Course, 2006.03, Completed

• Tokyo Medical and Dental University, Doctor's Course, 2010.03, Completed

Campus Career 【 display / non-display 】

Campus Career 【 display / non-display 】

• 2013.06

  -

  2018.03

  Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Matrix， Cell Signaling， Assistant Professor
• 2018.04

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  2020.06

  Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Matrix， Cell Signaling， Assistant Professor
• 2020.07

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  2021.03

  Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Matrix， Cell Signaling， Assistant Professor
• 2021.04

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  Now

  Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Matrix， Cell Signaling， Associate Professor

Research Areas 【 display / non-display 】

Research Areas 【 display / non-display 】

• Functional basic dentistry

Published Papers & Misc 【 display / non-display 】

Published Papers & Misc 【 display / non-display 】

• Fumiyuki Sasaki, Mikihito Hayashi, Takehito Ono, Tomoki Nakashima.. The regulation of RANKL by mechanical force. Journal of Bone and Mineral Metabolism. 2021.01; 39 (1): 34-44. ( DOI )

• Nasir K. Bashiruddin, Mikihito Hayashi, Masanobu Nagano, Yan Wu, Yukiko Matsunaga, Junichi Takagi, Tomoki Nakashima, Hiroaki Suga. Development of cyclic peptides with potent in vivo osteogenic activity through RaPID-based affinity maturation. Proceedings of the National Academy of Sciences of the United States of America. 2020.12; 117 (49): 31070-31077. ( DOI )

• Yosuke Tsuchiya, Mikihito Hayashi, Katashi Nagamatsu, Takehito Ono, Masaki Kamakura, Takanori Iwata, Tomoki Nakashima. The key royal jelly component 10-hydroxy-2-decenoic acid protects against bone loss by inhibiting NF-κB signaling downstream of FFAR4. Journal of Biological Chemistry. 2020.08; 385 (34): 12224-12232. ( DOI )

• Yoshitaka Kameo, Yuki Miya, Mikihito Hayashi, Tomoki Nakashima, Taiji Adachi. In silico experiments of bone remodeling explore metabolic diseases andtheir drug treatment. Science Advances. 2020.03; 6 (10): eaax0938.

• Takehito Ono, Mikihito Hayashi, Fumiyuki Sasaki, Tomoki Nakashima. RANKL biology: bone metabolism, the immune system, and beyond. Inflammation and Regeneration. 2020.02; 40 2. ( DOI )

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Conference Activities & Talks 【 display / non-display 】

Conference Activities & Talks 【 display / non-display 】

• 林幹人. Autoregulation of osteocyte Sema3A counteracts bone aging.. Japan Bone Academy 2020 2020.11.23

• Mikihito Hayashi. Estrogen-miRNA-Sema3A-Nrp1 axis regulates bone mass through autoregulation of osteocyte. 第16回Bone Biology Forum 2019.08.17

• Mikihito Hayashi, Tomoki Nakashima, Hiroshi Takayanagi. Autoregulation of osteocyte through estrogen-miRNA-Sema3A-Nrp1 axis. ASBMR 2017 Annual Meeting 2017.09.08