Personnel Information

写真a

OKAMOTO Tsukasa


Job title

Associate Professor

Research Areas, Keywords

pulmonary fibrosis, hypersensitivity pneumonitis, complement, Muc5b, KL-6

Graduating School 【 display / non-display

  • Hiroshima University, Faculty of Medicine, 2004.03, Graduated

Campus Career 【 display / non-display

  • 2013.04
    -
    2017.03
    Tokyo Medical and Dental University, Medical Hospital, Hospital Departments, Department of Internal Medicine, Pulmonary Medicine, Assistant Professor
  • 2017.04
    -
    2018.03
    Tokyo Medical and Dental University, Medical Hospital, Hospital Departments, Department of Internal Medicine, Pulmonary Medicine, Assistant Professor
  • 2019.04
    -
    2019.10
    Tokyo Medical and Dental University, Medical Hospital, Hospital Departments, Department of Internal Medicine, Pulmonary Medicine, Assistant Professor
  • 2019.11
    -
    2020.09
    Tokyo Medical and Dental University, Medical Hospital, Hospital Departments, Department of Internal Medicine, Pulmonary Medicine, Assistant Professor
  • 2020.10
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Endowed Departments, , Associate Professor

External Career 【 display / non-display

  • 2015.04
    -
    2019.03
    University of Colorado, Department of Medicine, Visiting Research Associate

Academic Society Affiliations 【 display / non-display

  • American Thoracic Society

Research Areas 【 display / non-display

  • Respiratory organ internal medicine

Qualification Acquired 【 display / non-display

  • Doctor

  • TOEFL

 

Research Theme 【 display / non-display

  • The pathology of hypersensitivity pneumonitis, 2008.04 - Now

  • Pulmonary fibrosis and Muc5b

  • Lung injury and complement activation, 2015.04 - Now

Published Papers & Misc 【 display / non-display

  • Gally F, Sasse SK, Kurche J, Gruca MA, Cardwell JH, Okamoto T, Chu HW, Hou X, Poirion O, Buchanan J, Preissl S, Ren B, Colgan SP, Dowell RD, Yang IV, Schwartz DA, Gerber AN. The MUC5B-associated variant, rs35705950, resides within an enhancer subject to lineage- and disease-dependent epigenetic remodeling. JCI insight. 2020.12; ( PubMed, DOI )

  • Okamato Y, Ghosh T, Okamoto T, Schuyler RP, Seifert J, Charry LL, Visser A, Feser M, Fleischer C, Pedrick C, August J, Moss L, Bemis EA, Norris JM, Kuhn KA, Demoruelle MK, Deane KD, Ghosh D, Holers VM, Hsieh EWY. Subjects at-risk for future development of rheumatoid arthritis demonstrate a PAD4-and TLR-dependent enhanced histone H3 citrullination and proinflammatory cytokine production in CD14<sup>hi</sup> monocytes. Journal of autoimmunity. 2020.12; 117 102581. ( PubMed, DOI )

  • Yamana T, Okamoto T, Ishizuka M, Hanzawa S, Ejima M, Shibata S, Miyazaki Y. IL-17A-Secreting Memory γδ T Cells Play a Pivotal Role in Sensitization and Development of Hypersensitivity Pneumonitis. Journal of immunology (Baltimore, Md. : 1950). 2020.12; ( PubMed, DOI )

  • Inoue Yukihisa, Okamoto Tsukasa, Honda Takayuki, Nukui Yoshihisa, Akashi Takumi, Takemura Tamiko, Tozuka Minoru, Miyazaki Yasunari. Disruption in the balance between apolipoprotein A-I and mast cell chymase in chronic hypersensitivity pneumonitis IMMUNITY INFLAMMATION AND DISEASE. 2020.12; 8 (4): 659-671. ( PubMed, DOI )

  • Iijima Y, Okamoto T, Shirai T, Mitsumura T, Sakakibara R, Honda T, Ishizuka M, Tateishi T, Tamaoka M, Aiboshi J, Otomo Y, Anzai T, Takahashi K, Miyazaki Y. MuLBSTA score is a useful tool for predicting COVID-19 disease behavior. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2020.10; ( PubMed, DOI )

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Conference Activities & Talks 【 display / non-display

  • Tsukasa Okamoto. Pulmonary fibrosis and MUC5B. 2019.07.19