Yang SS, Ishida T, Fujita K, Nakai Y, Ono T, Okazawa H. . PQBP1, an intellectual disability causative gene, affects bone development and growth. Biochemical and Biophysical Research Communications.. 2020.03; 523 894-899. ( DOI )

Tanaka H, Homma H, Fujita K, Kondo K, Yamada S, Jin X, Waragai M, Ohtomo G, Iwata A, Tagawa K, Atsuta N, Katsuno M, Tomita N, Furukawa K, Saito Y, Saito T, Ichise A, Shibata S, Arai H, Saido T, Sudol M, Muramatsu SI, Okano H, Mufson EJ, Sobue G, Murayama S, Okazawa H.. YAP-dependent necrosis occurs in early stages of Alzheimer's disease and regulates mouse model pathology. Nature Communications. 2020.01; 11 507. ( DOI )

Fujita K, Homma H, Kondo K, Ikuno M, Yamakado H, Tagawa K, Murayama S, Takahashi R, Okazawa H.. Ser46-Phosphorylated MARCKS Is a Marker of Neurite Degeneration at the Pre-aggregation Stage in PD/DLB Pathology. eNeuro. 2018.10; 5 (4): ENEURO.0217-18.2018.. ( DOI )

Tanaka H, Kondo K, Chen X, Homma H, Tagawa K, Kerever A, Aoki S, Saito T, Saido T, Muramatsu SI, Fujita K, Okazawa H. . The intellectual disability gene PQBP1 rescues Alzheimer's disease pathology. Molecular Psychiatry. 2018.10; 23 2090-2110. ( DOI )

Kawahori K, Hashimoto K, Yuan X, Tsujimoto K, Hanzawa N, Hamaguchi M, Kase S, Fujita K, Tagawa K, Okazawa H, Nakajima Y, Shibusawa N, Yamada M, Ogawa Y. . Mild Maternal Hypothyroxinemia During Pregnancy Induces Persistent DNA Hypermethylation in the Hippocampal Brain-Derived Neurotrophic Factor Gene in Mouse Offspring. Thyroid. 2018.03; 28 (3): 395-406. ( DOI )

Fujita K, Chen X, Homma H, Tagawa K, Amano M, Saito A, Imoto S, Akatsu H, Hashizume Y, Kaibuchi K, Miyano S, Okazawa H. . Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology. Nature Communications. 2018.01; 9 433. ( DOI )

Kyota Fujita, Ying Mao, Shigenori Uchida, Xigui Chen, Hiroki Shiwaku, Takuya Tamura, Hikaru Ito, Kei Watase, Hidenori Homma, Kazuhiko Tagawa, Marius Sudol, Hitoshi Okazawa. Developmental YAPdeltaC determines adult pathology in a model of spinocerebellar ataxia type 1. Nat Commun. 2017.11; 8 (1): 1864. ( PubMed, DOI )

Yamanishi, E., Hasegawa, K., Fujita, K., Ichinose, S., Yagishita, S., Murata, M., Tagawa, K., Akashi, T., Eishi, Y., Okazawa, H.. A novel form of necrosis, TRIAD, occurs in human Huntington's disease. Acta Neuropathologica Communications.. 2017.03; 5 (19): ( DOI )

Mao, Y., Chen, X., Xu, M.,Fujita, K., Sasabe, K.,Homma, H., Murata, M., Tagawa, K., Tamura, T., Kaye, J., Finkbeiner, S., Blandino, G., Sudol, M., Okazawa, H. . Targeting TEAD/YAP-transcription-dependent necrosis, TRIAD, ameliorates Huntington’s disease pathology. Hum Mol Genet.. 2016.09;

Imamura, T., Fujita, K., Tagawa, K., Ikura, T., Chen, X., Homma, H., Tamura, T., Mao, Y., Taniguchi, JB., Motoki, K., Nakabayashi, M., Ito, N., Yamada, K., Tomii, K., Okano, H., Kaye, J., Finkbeiner, S., Okazawa, H.. Identification of hepta-histidine as a candidate drug for Huntington’s disease by in silico-in vitro-in vivo-integrated screens of chemical libraries. Scientific Reports.. 2016.09; 6 33861.

Mao, Y., Chen, X., Xu, M.,Fujita, K., Sasabe, K.,Homma, H., Murata, M., Tagawa, K., Tamura, T., Kaye, J., Finkbeiner, S., Blandino, G., Sudol, M., Okazawa, H. . Targeting TEAD/YAP-transcription-dependent necrosis, TRIAD, ameliorates Huntington’s disease pathology. Hum Mol Genet.. 2016.09;

Fujita, K., Motoki, K., Tagawa, K., Chen, X., Hama, H., Nakajima, K., Homma, H., Tamura, T., Watanabe, H., Katsuno, M., Matsumi, C., Kajikawa, M., Saito, T., Saido, T., Sobue, G., Miyawaki, A., Okazawa, H.. HMGB1, a pathogenic molecule that induces neurite degeneration via TLR4-MARCKS, is a potential therapeutic target for Alzheimer's disease. Scientific Reports.. 2016.08; 6 31895.

藤田 慶大,岡澤 均. 「変性疾患の共通分子病態」 生体の科学. 2016.08; 67 (4): 309-313.

Taniguchi, JB., Kondo, K., Fujita, K., Chen, X., Homma, H., Sudo, T., Mao, Y., Watase, K., Tanaka, T., Tagawa, K., Tamura, T., Muramatsu, SI., Okazawa, H.. RpA1 ameliorates symptoms of mutant Ataxin-1 knock-in mice and enhances DNA damage repair. Hum. Mol. Genet.. 2016.08; ( PubMed, DOI )

Tagawa K, Homma H, Saito A, Fujita K, Chen X, Imoto S, Oka T, Ito H, Motoki K, Yoshida C, Hatsuta H, Murayama S, Iwatsubo T, Miyano S, Okazawa H. . Comprehensive phosphoproteome analysis unravels the core signaling network that initiates the earliest synapse pathology in preclinical Alzheimer's disease brain. Human Molecular Genetics.. 2015.01; 24 540-558. ( DOI )

Hikaru Ito, Kyota Fujita, Kazuhiko Tagawa, Xigui Chen, Hidenori Homma, Toshikazu Sasabe, Jun Shimizu, Shigeomi Shimizu, Takuya Tamura, Shin-Ichi Muramatsu, Hitoshi Okazawa. HMGB1 facilitates repair of mitochondrial DNA damage and extends the lifespan of mutant ataxin-1 knock-in mice. EMBO Mol Med. 2014.12; ( PubMed, DOI )

Ito H, Shiwaku H, Yoshida C, Homma H, Luo H, Chen X, Fujita K, Musante L, Fischer U, Frints S G M, Romano C, Ikeuchi Y, Shimamura T, Imoto S, Miyano S, Muramatsu S-I, Kawauchi T, Hoshino M, Sudol M, Arumughan A, Wanker E E, Rich T, Schwartz C, Matsuzaki F, Bonni A, Kalscheuer V M, Okazawa H. In utero gene therapy rescues microcephaly caused by Pqbp1-hypofunction in neural stem progenitor cells. Mol Psychiatry. 2014.07; ( PubMed, DOI )

Chan Li, Hikaru Ito, Kyota Fujita, Hiroki Shiwaku, Yunlong Qi, Kazuhiko Tagawa, Takuya Tamura, Hitoshi Okazawa. Sox2 transcriptionally regulates PQBP1, an intellectual disability-microcephaly causative gene, in neural stem progenitor cells. PLoS ONE. 2013.07; 8 (7): e68627. ( PubMed, DOI )

Kyota Fujita, Yoko Nakamura, Tsutomu Oka, Hikaru Ito, Takuya Tamura, Kazuhiko Tagawa, Toshikazu Sasabe, Asuka Katsuta, Kazumi Motoki, Hiroki Shiwaku, Masaki Sone, Chisato Yoshida, Masahisa Katsuno, Yoshinobu Eishi, Miho Murata, J Paul Taylor, Erich E Wanker, Kazuteru Kono, Satoshi Tashiro, Gen Sobue, Albert R La Spada, Hitoshi Okazawa. A functional deficiency of TERA/VCP/p97 contributes to impaired DNA repair in multiple polyglutamine diseases. Nat Commun. 2013.05; 4 1816. ( PubMed, DOI )

Kyota Fujita, Xigui Chen, Hidenori Homma, Kazuhiko Tagawa, Hitoshi Okazawa. Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology. 第60回日本神経学会学術大会 2019.05.22 大阪国際会議場(大阪府大阪市)

藤田慶大、陳西貴、本間秀典、田川一彦、岡澤均. アルツハイマー病と前頭側頭葉変性症に共通する異常タウリン酸化とシナプス障害. 第37回日本認知症学会学術集会 2018.10.12 ロイトン札幌・札幌市教育文化会館（北海道　札幌市）

藤田 慶大、Ying Mao、陳 西貴、山西 恵美子、本間 秀典、田川 一彦、岡澤 均　. 「ハンチントン病における新規ネクローシスTRIADの分子病態. 第41回日本神経科学大会 2018.07.28 神戸国際会議場（神戸）

藤田 慶大、毛 瀅、内田 成則、陳 西貴、塩飽 裕紀、田村 拓也、伊藤 日加瑠、本間 秀典、田川 一彦、岡澤 均. Developmental YAPdeltaC determines adult pathology in a mouse model of spinocerebellarataxia type 1.”. 第59回日本神経学会学術大会 2018.05.23 ロイトン札幌・さっぽろ芸術文化の館・札幌市教育文化会館（札幌）

Kyota Fujita, Kazumi Motoki, Kazuhiko Tagawa, Xigui Chen, Hiroshi Hama, Kazuyuki Nakajima, Hidenori Homma, Takuya Tamura, Atsushi Miyawaki, Hitoshi Okazawa.. HMGB1 TRIGGERS NEURITE DEGENERATION VIA TLR4-MARCKS, AND IS A POTENTIAL THERAPEUTIC TARGET FOR ALZHEIMER’S DISEASE. XXIII World Congress of Neurology (WCN 2017) 合同開催：第58回日本神経学会学術大会・第23回世界神経学会議 2017.09.17 Kyoto International Conference Center (日本、京都)

Juliana Bosso Taniguchi, Kanoh Kondo, Kyota Fujita, Xigui Chen, Hidenori Homma , Ying Mao , Kazuhiko Tagawa , Hitoshi Okazawa.. RPA1 AMELIORATES SYMPTOMS OF MUTANT ATAXIN-1 KNOCK-IN MICE AND ENHANCE DNA DAMAGE REPAIR. XXIII World Congress of Neurology (WCN 2017) 合同開催：第58回日本神経学会学術大会・第23回世界神経学会議 2017.09.17 Kyoto International Conference Center (日本、京都)

Xigui Chen, Mao Ying, Xu Min, Kyota Fujita, Kazumi Motoki, Toshikazu Sasabe, Hidenori Homma, Miho Murata, Kazuhiko Tagawa, Takuya Tamura, Kaye Julia, Steven Finkbeiner, Giovanni Blandino, Marius Sudol, Kanoh Kondo, Hitoshi Okazawa.. Targeting TEAD/YAP-transcription-dependent necrosis, TRIAD, ameliorates Huntington's disease pathology. 第40回日本神経科学大会 2017.07.22 Kyoto International Conference Center (日本、京都)

Kyota Fujita, Kazumi Motoki, Kazuhiko Tagawa, Xigui Chen, Hiroshi Hama, Kazuyuki Nakajima, Hidenori Homma, Takuya Tamura, Masahisa Katsuno, Takashi Saito, Takaomi Saido, Gen Sobue, Atsushi Miyawaki, Hitoshi Okazawa. . HMGB1, a pathogenic molecule that induces neurite degeneration via TLR4-MARCKS, is a potential therapeutic target for Alzheimer's disease. 第40回日本神経科学大会 2017.07.20 幕張メッセ（幕張市）

Juliana Bosso Taniguchi, Kanoh Kondo, Kyota Fujita, Chen Xigui, Hidenori Homma, Takeaki Sudo,Ying Mao, Kei Watase, Toshihiro Tanaka, Kazuhiko Tagawa, Takuya Tamura, Shin-Ichi Muramatsu, Hitoshi Okazawa.. RpA1 ameliorates symptoms of mutant ataxin-1 knock-in mice and enhances DNA damage repair. 第40回日本神経科学大会 2017.07.20 幕張メッセ（幕張市）

3. Fujita, K., Nakamura, Y., Oka, T., Ito, H., Tamura, T., Tagawa, K., Sasabe, T., Katsuta, A., Motoki, K., Shiwaku, H., Yoshida, C., Sone, M., Okazawa, H.. A functional deficiency of TERA/VCP/p97 contributes to impaired DNA repair in multiple polyglutamine diseases.. Neuroscience2014 2014.09.12