Toru Kanno, Kazuo Otsuka, Ryoichi Saito, Katsuhiro Ito, Shigeki Koterazawa, Shinya Somiya, Takao Haitani, Yoshihito Higashi, Hitoshi Yamada. Minimally invasive total pelvic exenteration for symptomatic locally advanced prostate cancer with rectal invasion: Indications and technical considerations. Asian J Endosc Surg. 2024.04; 17 (2): e13290. ( PubMed, DOI )

Tatsuya Suzuki, Yuka Hayakawa, Shun Kaneko, Kento Takenaka, Keiya Watakabe, Yuko Kinowaki, Akira Takemoto, Kazuo Ohtsuka, Yasuhiro Asahina, Ryuichi Okamoto. Granulomatous hepatitis with Crohn's disease: a case report. Clin J Gastroenterol. 2024.03; Online ahead of print (3): 551-556. ( PubMed, DOI )

Yoshitaka Nishikawa, Takahiro Horimatsu, Shiro Oka, Takeshi Yamada, Keigo Mitsui, Hironori Yamamoto, Keiichi Takahashi, Akio Shiomi, Kinichi Hotta, Yoji Takeuchi, Toshio Kuwai, Fumio Ishida, Shin-Ei Kudo, Shoichi Saito, Masashi Ueno, Eiji Sunami, Tomoki Yamano, Michio Itabashi, Kazuo Ohtsuka, Yusuke Kinugasa, Takayuki Matsumoto, Tamotsu Sugai, Toshio Uraoka, Koichi Kurahara, Shigeki Yamaguchi, Tomohiro Kato, Masazumi Okajima, Hiroshi Kashida, Fumihiko Fujita, Hiroaki Ikematsu, Masaaki Ito, Motohiro Esaki, Masaya Kawai, Takashi Yao, Madoka Hamada, Keiji Koda, Yasumori Fukai, Koji Komori, Yusuke Saitoh, Yukihide Kanemitsu, Hiroyuki Takamaru, Kazutaka Yamada, Hiroaki Nozawa, Tetsuji Takayama, Kazutomo Togashi, Eiji Shinto, Takehiro Torisu, Akira Toyoshima, Naoki Ohmiya, Takeshi Kato, Eigo Otsuji, Shinji Nagata, Yojiro Hashiguchi, Kenichi Sugihara, Yoichi Ajioka, Shinji Tanaka. Outcomes of Metastatic and Unresectable Small Bowel Adenocarcinoma in Japan According to the Treatment Strategy: A Nationwide Observational Study. JCO Glob Oncol. 2024.02; 10 e2300392. ( PubMed, DOI )

Takanori Kuroki, Yasuharu Maeda, Shin-Ei Kudo, Noriyuki Ogata, Marietta Iacucci, Kazumi Takishima, Yutaro Ide, Tomoya Shibuya, Shigenori Semba, Jiro Kawashima, Shun Kato, Yushi Ogawa, Katsuro Ichimasa, Hiroki Nakamura, Takemasa Hayashi, Kunihiko Wakamura, Hideyuki Miyachi, Toshiyuki Baba, Tetsuo Nemoto, Kazuo Ohtsuka, Masashi Misawa. A novel artificial intelligence-assisted "vascular healing" diagnosis for prediction of future clinical relapse in patients with ulcerative colitis: a prospective cohort study. Gastrointest Endosc. 2024.01; Online ahead of print (1): 97-108. ( PubMed, DOI )

Nanako Hashido, Masanori Kobayashi, Ami Kawamoto, Suguru Mabuchi, Hiromune Katsuda, Kazuo Ohtsuka, Yasuhiro Asahina, Masayoshi Hashimoto, Ryuichi Okamoto. Sphincter of Oddi dysfunction that could not be diagnosed with Rome IV: a case report. Clin J Gastroenterol. 2023.12; 16 (6): 913-918. ( PubMed, DOI )

Ami Kawamoto, Kento Takenaka, Shuji Hibiya, Yoshio Kitazume, Hiromichi Shimizu, Toshimitsu Fujii, Eiko Saito, Kazuo Ohtsuka, Ryuichi Okamoto. Combination of leucine-rich alpha-2 glycoprotein and fecal markers detect Crohn's disease activity confirmed by balloon-assisted enteroscopy. Intest Res. 2023.11; Online ahead of print (1): 65-74. ( PubMed, DOI )

Shuji Hibiya, Takashi Fujii, Toshimitsu Fujii, Shinji Suzuki, Mayumi Kondo, Shinya Ooka, Yohei Furumoto, Seishin Azuma, Kei Tanaka, Hitoshi Kurata, Shohei Tanaka, Masayuki Kurosaki, Kazuyoshi Nagayama, Fumihiko Kusano, Yasuhiro Iizuka, Takahiro Kawamura, Hidekazu Ikemiyagi, Shinya Sakita, Tsunehito Yauchi, Hideki Watanabe, Ami Kawamoto, Yusuke Matsuyama, Kazuo Ohtsuka, Ryuichi Okamoto. COVID-19 severity is associated with the risk of gastrointestinal bleeding. BMJ Open Gastroenterol. 2023.11; 10 (1): ( PubMed, DOI )

Masanori Kobayashi, Hiromune Katsuda, Kazuo Ohtsuka, Ryuichi Okamoto. Comparison of guidewires for successful cannulation of biliary stenosis and targeting of biliary branches in ERCP. Endosc Int Open. 2023.09; 11 (9): E805-E810. ( PubMed, DOI )

Kento Takenaka, Ami Kawamoto, Yoshio Kitazume, Toshimitsu Fujii, Yumi Udagawa, Hiromichi Shimizu, Shuji Hibiya, Masakazu Nagahori, Kazuo Ohtsuka, Mamoru Watanabe, Ryuichi Okamoto. Transmural Remission Characterized by High Biologic Concentrations Demonstrates Better Prognosis in Crohn's Disease. J Crohns Colitis. 2023.06; 17 (6): 855-862. ( PubMed, DOI )

Kento Takenaka, Yoshio Kitazume, Ami Kawamoto, Toshimitsu Fujii, Yumi Udagawa, Ryosuke Wanatabe, Hiromichi Shimizu, Shuji Hibiya, Masakazu Nagahori, Kazuo Ohtsuka, Hiroyuki Sato, Akihiro Hirakawa, Mamoru Watanabe, Ryuichi Okamoto. Serum Leucine-Rich α2 Glycoprotein: A Novel Biomarker for Transmural Inflammation in Crohn's Disease. Am J Gastroenterol. 2023.06; 118 (6): 1028-1035. ( PubMed, DOI )

Fujiwara S, Kawamoto A, Motobayashi M, Hibiya S, Takenaka K, Shimizu H, Saito E, Fujii T, Nagahori M, Kawata D, Umezawa N, Hosoya T, Yasuda S, Ohtsuka K, Okamoto R. Hemorrhagic gastric ulcer in a patient with Behcet's disease successfully treated with infliximab. DEN open. 2023.04; 3 (1): e196. ( PubMed, DOI )

Eiko Saito, Kazuo Ohtsuka, Ami Kawamoto, Toshimitsu Fujii, Kento Takenaka, Shuji Hibiya, Hiromichi Shimizu, Masakazu Nagahori, Shohei Tomii, Ryuichi Okamoto. A case of venous stasis colitis possibly caused by eplerenone. Clin J Gastroenterol. 2023.02; 16 (1): 69-72. ( PubMed, DOI )

Maeda Y, Kudo SE, Ogata N, Kuroki T, Takashina Y, Takishima K, Ogawa Y, Ichimasa K, Mori Y, Kudo T, Hayashi T, Miyachi H, Ishida F, Nemoto T, Ohtsuka K, Misawa M. Use of advanced endoscopic technology for optical characterization of neoplasia in patients with ulcerative colitis: Systematic review. Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society. 2022.11; 34 (7): 1297-1310. ( PubMed, DOI )

Ainechi D, Misawa M, Barua I, Larsen SLV, Paulsen V, Garborg KK, Aabakken L, Tønnesen CJ, Løberg M, Kalager M, Kudo SE, Hotta K, Ohtsuka K, Saito S, Ikematsu H, Saito Y, Matsuda T, Itoh H, Mori K, Bretthauer M, Mori Y. Impact of artificial intelligence on colorectal polyp detection for early-career endoscopists: an international comparative study. Scandinavian journal of gastroenterology. 2022.10; 57 (10): 1272-1277. ( PubMed, DOI )

Fujiwara S, Kobayashi M, Ohtsuka K, Tanabe M, Okamoto R. The Double-Max method: a novel method for gallbladder epithelial biopsy. VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy. 2022.09; 7 (9): 334-336. ( PubMed, DOI )

Kazumi Takishima, Yasuharu Maeda, Noriyuki Ogata, Masashi Misawa, Yuichi Mori, Mayumi Homma, Tetsuo Nemoto, Yuki Miyata, Yoshika Akimoto, Kentaro Mochida, Yuki Takashina, Kenta Tanaka, Katsuro Ichimasa, Hiroki Nakamura, Seiko Sasanuma, Toyoki Kudo, Takemasa Hayashi, Kunihiko Wakamura, Hideyuki Miyachi, Toshiyuki Baba, Fumio Ishida, Kazuo Ohtsuka, Shin-Ei Kudo. Beyond complete endoscopic healing: Goblet appearance using an endocytoscope to predict future sustained clinical remission in ulcerative colitis. Dig Endosc. 2022.07; 34 (5): 1030-1039. ( PubMed, DOI )

Masanori Kobayashi, Shomei Ryozawa, Kazuo Ohtsuka, Minoru Tanabe, Ryuichi Okamoto. A convenient and reliable method for endoscopic mapping biopsy of cholangiocarcinoma using a double-lumen cytology device. VideoGIE. 2022.05; 7 (5): 182-184. ( PubMed, DOI )

Shuji Hibiya, Kazuo Ohtsuka, Kento Takenaka, Ami Kawamoto, Yusuke Matsuyama, Yumi Udagawa, Maiko Motobayashi, Hiromichi Shimizu, Toshimitsu Fujii, Eiko Saito, Masakazu Nagahori, Ryuichi Okamoto, Mamoru Watanabe. Mucosal healing of small intestinal stricture is associated with improved prognosis post-dilation in Crohn's disease. BMC Gastroenterol. 2022.05; 22 (1): 218. ( PubMed, DOI )

Yoshio Kitazume, Kento Takenaka, Kazuo Ohtsuka, Yasuo Ozawa, Koichiro Kimura, Ryosuke Watanabe, Junichi Tsuchiya, Toshimitsu Fujii, Masakazu Nagahori, Mamoru Watanabe, Ukihide Tateishi. Motility Mapping Quantification Using the Classical Optical Flow Algorithm for Small Bowel Crohn's Disease: Comparison with Balloon-assisted Enteroscopy Findings. Magn Reson Med Sci. 2022.05; 22 (3): Online ahead of print-334. ( PubMed, DOI )

Yasuharu Maeda, Shin-Ei Kudo, Noriyuki Ogata, Masashi Misawa, Marietta Iacucci, Mayumi Homma, Tetsuo Nemoto, Kazumi Takishima, Kentaro Mochida, Hideyuki Miyachi, Toshiyuki Baba, Kensaku Mori, Kazuo Ohtsuka, Yuichi Mori. Evaluation in real-time use of artificial intelligence during colonoscopy to predict relapse of ulcerative colitis: a prospective study. Gastrointest Endosc. 2022.04; 95 (4): 747-756.e2. ( PubMed, DOI )

Kento Takenaka, Ami Kawamoto, Ryuichi Okamoto, Mamoru Watanabe, Kazuo Ohtsuka. Artificial intelligence for endoscopy in inflammatory bowel disease. Intest Res. 2022.04; 20 (2): 165-170. ( PubMed, DOI )

Ami Kawamoto, Kento Takenaka, Ryuichi Okamoto, Mamoru Watanabe, Kazuo Ohtsuka. Systematic review of artificial intelligence-based image diagnosis for inflammatory bowel disease. Dig Endosc. 2022.04; 34 (7): 1311-1319. ( PubMed, DOI )

Isshiki K, Kamiya T, Endo A, Okamoto K, Osumi T, Kawai T, Arai K, Tomizawa D, Ohtsuka K, Nagahori M, Imai K, Kato M, Kanegane H. Vedolizumab therapy for pediatric steroid-refractory gastrointestinal acute graft-versus-host disease. International journal of hematology. 2022.04; 115 (4): 590-594. ( PubMed, DOI )

Kishi M, Hirai F, Takatsu N, Hisabe T, Takada Y, Beppu T, Takeuchi K, Naganuma M, Ohtsuka K, Watanabe K, Matsumoto T, Esaki M, Koganei K, Sugita A, Hata K, Futami K, Ajioka Y, Tanabe H, Iwashita A, Shimizu H, Arai K, Suzuki Y, Hisamatsu T. A review on the current status and definitions of activity indices in inflammatory bowel disease: how to use indices for precise evaluation. Journal of gastroenterology. 2022.04; 57 (4): 246-266. ( PubMed, DOI )

Kim ES, Tae CH, Jung SA, Park DI, Im JP, Eun CS, Yoon H, Jang BI, Ogata H, Fukuhara K, Hirai F, Ohtsuka K, Liu J, Cao Q, Clinical Research Committee of the Asian Organization for Crohn’s and Colitis. Perspectives of East Asian patients and physicians on complementary and alternative medicine use for inflammatory bowel disease: results of a cross-sectional, multinational study. Intestinal research. 2022.04; 20 (2): 192-202. ( PubMed, DOI )

Takenaka K, Fujii T, Kawamoto A, Suzuki K, Shimizu H, Maeyashiki C, Yamaji O, Motobayashi M, Igarashi A, Hanazawa R, Hibiya S, Nagahori M, Saito E, Okamoto R, Ohtsuka K, Watanabe M. Deep neural network for video colonoscopy of ulcerative colitis: a cross-sectional study. The lancet. Gastroenterology & hepatology. 2022.03; 7 (3): 230-237. ( PubMed, DOI )

Hiromichi Shimizu, Toshimitsu Fujii, Kenji Kinoshita, Ami Kawamoto, Shuji Hibiya, Kento Takenaka, Eiko Saito, Masakazu Nagahori, Kazuo Ohtsuka, Mamoru Watanabe, Ryuichi Okamoto. Intravenous tacrolimus is a superior induction therapy for acute severe ulcerative colitis compared to oral tacrolimus. BMC Gastroenterol. 2021.12; 21 (1): 494. ( PubMed, DOI )

Noriyuki Ogata, Kazuo Ohtsuka, Masataka Ogawa, Yasuharu Maeda, Fumio Ishida, Shin-Ei Kudo. Image-Enhanced Capsule Endoscopy Improves the Identification of Small Intestinal Lesions. Diagnostics (Basel). 2021.11; 11 (11): ( PubMed, DOI )

Kento Takenaka, Ami Kawamoto, Kazuo Ohtsuka. Editorial: higher concentrations of cytokine blockers are needed to obtain small bowel mucosal healing during maintenance therapy in Crohn's disease-authors' reply. Aliment Pharmacol Ther. 2021.10; 54 (8): 1087. ( PubMed, DOI )

Ito R, Kobayashi M, Ohtsuka K, Tanabe M, Okamoto R. A rare case of hepatocellular carcinoma with bile duct invasion diagnosed by peroral cholangioscopy. VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy. 2021.08; 6 (8): 354-357. ( PubMed, DOI )

Mori Y, Kudo SE, Misawa M, Hotta K, Kazuo O, Saito S, Ikematsu H, Saito Y, Matsuda T, Kenichi T, Kudo T, Nemoto T, Itoh H, Mori K. Artificial intelligence-assisted colonic endocytoscopy for cancer recognition: a multicenter study. Endoscopy international open. 2021.07; 9 (7): E1004-E1011. ( PubMed, DOI )

Takenaka K, Kawamoto A, Hibiya S, Suzuki K, Fujii T, Motobayashi M, Shimizu H, Nagahori M, Saito E, Okamoto R, Watanabe M, Ohtsuka K. Higher concentrations of cytokine blockers are needed to obtain small bowel mucosal healing during maintenance therapy in Crohn's disease. Alimentary pharmacology & therapeutics. 2021.07; 54 (8): 1052-1060. ( PubMed, DOI )

Maeda Y, Kudo SE, Ogata N, Misawa M, Mori Y, Mori K, Ohtsuka K. Can artificial intelligence help to detect dysplasia in patients with ulcerative colitis? Endoscopy. 2021.07; 53 (7): E273-E274. ( PubMed, DOI )

Kawamoto A, Takenaka K, Hibiya S, Ohtsuka K, Okamoto R, Watanabe M. Serum Leucine-Rich α₂ Glycoprotein: A Novel Biomarker For Small Bowel Mucosal Activity in Crohn's Disease. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2021.06; 20 (5): e1196-e1200. ( PubMed, DOI )

Kitazume Y, Takenaka K, Ohtsuka K, Kimura K, Ogihara Y, Fujioka T, Tsuchiya J, Fujii T, Watanabe M, Tateisi U. Crohn disease: magnetic resonance enterocolonography features of endoscopic ulcer stages reclassified with the healing process and the relationships to prognoses. Japanese journal of radiology. 2021.05; 39 (5): 459-476. ( PubMed, DOI )

Takenaka K, Ohtsuka K, Fujii T, Oshima S, Okamoto R, Watanabe M. Deep Neural Network Accurately Predicts Prognosis of Ulcerative Colitis Using Endoscopic Images. Gastroenterology. 2021.05; 160 (6): 2175-2177.e3. ( PubMed, DOI )

Maeda Y, Kudo SE, Takishima K, Misawa M, Ogata N, Ohtsuka K. Letter: the combination of histologic remission and Mayo endoscopic score 1 as a suitable therapeutic target in ulcerative colitis. Alimentary pharmacology & therapeutics. 2021.04; 53 (8): 955-956. ( PubMed, DOI )

Kato S, Shimizu H, Tomii S, Uchida H, Kawamoto A, Hibiya S, Motobayashi M, Takenaka K, Fujii T, Saito E, Nagahori M, Ohtsuka K, Negi M, Akashi T, Matsuyama T, Kinugasa Y, Watanabe M. Substantial Epstein-Barr virus reactivation in a case of severe refractory ulcerative colitis: a possible role in exacerbation. Clinical journal of gastroenterology. 2021.04; 14 (2): 584-588. ( PubMed, DOI )

Kaneshiro M, Takenaka K, Suzuki K, Fujii T, Hibiya S, Kawamoto A, Motobayashi M, Shimizu H, Nagahori M, Saito E, Okamoto R, Ohtsuka K, Watanabe M. Pancolonic endoscopic and histologic evaluation for relapse prediction in patients with ulcerative colitis in clinical remission. Alimentary pharmacology & therapeutics. 2021.04; 53 (8): 900-907. ( PubMed, DOI )

Saito Y, Kodashima S, Matsuda T, Matsuda K, Fujishiro M, Tanaka K, Kobayashi K, Katada C, Horimatsu T, Muto M, Ohtsuka K, Oda I, Kato M, Kida M, Hoteya S, Yamamoto H, Ryozawa S, Iwakiri R, Kutsumi H, Kato M, Haruma K, Fujimoto K, Iishi H, Ogata H, Uemura N, Kaminishi M, Tajiri H, Inoue H. Current status of diagnostic and therapeutic colonoscopy in Japan: The Japan Endoscopic Database Project. Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society. 2021.03; ( PubMed, DOI )

Tsugeno Y, Kawachi H, Kirimura S, Hirota Y, Shintaku H, Ito T, Kikuchi A, Ohtsuka K, Akashi T, Kitagawa M. Adenocarcinoma arising in the multiple heterotopic submucosal glands of the intestine in a Satoyoshi syndrome patient: A case report. Pathology international. 2021.02; 71 (2): 147-154. ( PubMed, DOI )

Kudo SE, Maeda Y, Ogata N, Misawa M, Ogawa Y, Takishima K, Ishiyama M, Mochizuki K, Minegishi Y, Ogura Y, Abe M, Okumura T, Matsudaira S, Ishigaki T, Sasanuma S, Mori Y, Kudo T, Hayashi T, Wakamura K, Miyachi H, Baba T, Ishida F, Nemoto T, Hamatani S, Ohtsuka K. Combined endocytoscopy with pit pattern diagnosis in ulcerative colitis-associated neoplasia: Pilot study. Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society. 2021.02; 34 (1): 133-143. ( PubMed, DOI )

Hibiya S, Matsuyama Y, Fujii T, Maeyashiki C, Saito E, Ito K, Shimizu H, Kawamoto A, Motobayashi M, Takenaka K, Nagahori M, Kurosaki M, Yauchi T, Ohtsuka K, Fujiwara T, Okamoto R, Watanabe M. 5-aminosalicylate-intolerant patients are at increased risk of colectomy for ulcerative colitis. Alimentary pharmacology & therapeutics. 2021.01; 53 (1): 103-113. ( PubMed, DOI )

Yasuharu Maeda, Shin-Ei Kudo, Noriyuki Ogata, Yuichi Mori, Masashi Misawa, Mayumi Homma, Tetsuo Nemoto, Masataka Ogawa, Seiko Sasanuma, Yuta Sato, Shinichi Kataoka, Yuta Kouyama, Tatsuya Sakurai, Kenta Igarashi, Yushi Ogawa, Kazuki Kato, Katsuro Ichimasa, Hiroki Nakamura, Toyoki Kudo, Takemasa Hayashi, Kunihiko Wakamura, Toshiyuki Baba, Haruhiro Inoue, Kazuo Ohtsuka. Endocytoscopic intramucosal capillary network changes and crypt architecture abnormalities can predict relapse in patients with an ulcerative colitis Mayo endoscopic score of 1. Dig Endosc. 2020.11; 32 (7): 1082-1091. ( PubMed, DOI )

Yoshio Kitazume, Junichi Tsuchiya, Kento Takenaka, Kazuo Ohtsuka, Koichiro Kimura, Ryosuke Watanabe, Tomoyuki Fujioka, Toshimitsu Fujii, Mamoru Watanabe, Ukihide Tateisi. High b-value computed diffusion-weighted imaging for differentiating bowel inflammation in Crohn's disease. Eur J Radiol. 2020.10; 133 109362. ( PubMed, DOI )

Yuichi Mori, Shin-Ei Kudo, James E East, Amit Rastogi, Michael Bretthauer, Masashi Misawa, Masau Sekiguchi, Takahisa Matsuda, Yutaka Saito, Hiroaki Ikematsu, Kinichi Hotta, Kazuo Ohtsuka, Toyoki Kudo, Kensaku Mori. Cost savings in colonoscopy with artificial intelligence-aided polyp diagnosis: an add-on analysis of a clinical trial (with video). Gastrointest Endosc. 2020.10; 92 (4): 905-911.e1. ( PubMed, DOI )

Kento Takenaka, Kazuo Ohtsuka, Kohei Suzuki, Mamoru Watanabe. Reply to GASTRO-D- 20-00591 Gastroenterology. 2020.10; 159 (4): 1626-1627. ( PubMed, DOI )

Hayato Itoh, Yukitaka Nimura, Yuichi Mori, Masashi Misawa, Shin-Ei Kudo, Kinichi Hotta, Kazuo Ohtsuka, Shoichi Saito, Yutaka Saito, Hiroaki Ikematsu, Yuichiro Hayashi, Masahiro Oda, Kensaku Mori. Robust endocytoscopic image classification based on higher-order symmetric tensor analysis and multi-scale topological statistics. Int J Comput Assist Radiol Surg. 2020.09; 15 (12): 2049-Online ahead of print. ( PubMed, DOI )

Shin-Ei Kudo, Katsuro Ichimasa, Benjamin Villard, Yuichi Mori, Masashi Misawa, Shoichi Saito, Kinichi Hotta, Yutaka Saito, Takahisa Matsuda, Kazutaka Yamada, Toshifumi Mitani, Kazuo Ohtsuka, Akiko Chino, Daisuke Ide, Kenichiro Imai, Yoshihiro Kishida, Keiko Nakamura, Yasumitsu Saiki, Masafumi Tanaka, Shu Hoteya, Satoshi Yamashita, Yusuke Kinugasa, Masayoshi Fukuda, Toyoki Kudo, Hideyuki Miyachi, Fumio Ishida, Hayato Itoh, Masahiro Oda, Kensaku Mori. Artificial intelligence system to determine risk of T1 colorectal cancer metastasis to lymph node. Gastroenterology. 2020.09; 160 (4): 1075-Online ahead of print.. ( PubMed, DOI )

Shin-Ei Kudo, Masashi Misawa, Yuichi Mori, Kinichi Hotta, Kazuo Ohtsuka, Hiroaki Ikematsu, Yutaka Saito, Kenichi Takeda, Hiroki Nakamura, Katsuro Ichimasa, Tomoyuki Ishigaki, Naoya Toyoshima, Toyoki Kudo, Takemasa Hayashi, Kunihiko Wakamura, Toshiyuki Baba, Fumio Ishida, Haruhiro Inoue, Hayato Itoh, Masahiro Oda, Kensaku Mori. Artificial intelligence-assisted system improves endoscopic identification of colorectal neoplasms. Clin Gastroenterol Hepatol. 2020.07; 18 (8): 1874-1881.e2. ( PubMed, DOI )

Masashi Misawa, Shin-Ei Kudo, Yuichi Mori, Kinichi Hotta, Kazuo Ohtsuka, Takahisa Matsuda, Shoichi Saito, Toyoki Kudo, Toshiyuki Baba, Fumio Ishida, Hayato Itoh, Masahiro Oda, Kensaku Mori. Development of a computer-aided detection system for colonoscopy and a publicly accessible large colonoscopy video database (with video). Gastrointest Endosc. 2020.07; 93 (4): 960-Online ahead of print. ( PubMed, DOI )

Hiromichi Shimizu, Toshimitsu Fujii, Shuji Hibiya, Maiko Motobayashi, Kohei Suzuki, Kento Takenaka, Eiko Saito, Masakazu Nagahori, Kazuo Ohtsuka, Mamoru Watanabe. Rapid prediction of 1-year efficacy of tofacitinib for treating refractory ulcerative colitis. Intest Res. 2020.06; 19 (1): 115-Online ahead of print.. ( PubMed, DOI )

Takenaka K, Ohtsuka K, Fujii T, Negi M, Suzuki K, Shimizu H, Oshima S, Akiyama S, Motobayashi M, Nagahori M, Saito E, Matsuoka K, Watanabe M. Development and Validation of a Deep Neural Network for Accurate Evaluation of Endoscopic Images From Patients With Ulcerative Colitis. Gastroenterology. 2020.06; 158 (8): 2150-2157. ( PubMed, DOI )

Takenaka K, Kitazume Y, Fujii T, Tsuchiya K, Watanabe M, Ohtsuka K. Objective evaluation for treat to target in Crohn's disease. Journal of gastroenterology. 2020.06; 55 (6): 579-587. ( PubMed, DOI )

Masayuki Kato, Kiyohito Tanaka, Mitsuhiro Kida, Shomei Ryozawa, Koji Matsuda, Mitsuhiro Fujishiro, Yutaka Saito, Kazuo Ohtsuka, Ichiro Oda, Chikatoshi Katada, Kiyonori Kobayashi, Shu Hoteya, Takahiro Horimatsu, Shinya Kodashima, Takahisa Matsuda, Manabu Muto, Hironori Yamamoto, Ryuichi Iwakiri, Hiromu Kutsumi, Hiroaki Miyata, Mototsugu Kato, Ken Haruma, Kazuma Fujimoto, Naomi Uemura, Michio Kaminishi, Hisao Tajiri. Multicenter database registry for endoscopic retrograde cholangiopancreatography: Japan Endoscopic Database Project. Dig Endosc. 2020.05; 32 (4): 494-502. ( PubMed, DOI )

Kento Takenaka, Maiko Kimura, Kazuo Ohtsuka. Colonic strictures mimicking Crohn's disease. Gut. 2019.11; 70 (2): 233-387. ( PubMed, DOI )

Nagaishi T, Yamada D, Suzuki K, Fukuyo R, Saito E, Fukuda M, Watabe T, Tsugawa N, Takeuchi K, Yamamoto K, Arai A, Ohtsuka K, Watanabe M. Indolent T cell lymphoproliferative disorder with villous atrophy in small intestine diagnosed by single-balloon enteroscopy. Clinical journal of gastroenterology. 2019.10; 12 (5): 434-440. ( PubMed, DOI )

Kento Takenaka, Toshimitsu Fujii, Kohei Suzuki, Hiromichi Shimizu, Maiko Motobayashi, Shuji Hibiya, Eiko Saito, Masakazu Nagahori, Mamoru Watanabe, Kazuo Ohtsuka. Small Bowel Healing Detected by Endoscopy in Patients With Crohn's Disease After Treatment With Antibodies Against Tumor Necrosis Factor. Clin. Gastroenterol. Hepatol.. 2019.08; 18 (7): 1545-1552. ( PubMed, DOI )

Motobayashi M, Matsuoka K, Takenaka K, Fujii T, Nagahori M, Ohtsuka K, Iwamoto F, Tsuchiya K, Negi M, Eishi Y, Watanabe M. Predictors of mucosal healing during induction therapy in patients with acute moderate-to-severe ulcerative colitis. Journal of gastroenterology and hepatology. 2019.06; 34 (6): 1004-1010. ( PubMed, DOI )

Shintaro Akiyama, Katsuyoshi Matsuoka, Kyoko Fukuda, Shunsuke Hamada, Mikiko Shimizu, Kosaku Nanki, Shinta Mizuno, Hiroki Kiyohara, Mari Arai, Shinya Sugimoto, Yasushi Iwao, Haruhiko Ogata, Tadakazu Hisamatsu, Makoto Naganuma, Maiko Motobayashi, Kohei Suzuki, Kento Takenaka, Toshimitsu Fujii, Eiko Saito, Masakazu Nagahori, Kazuo Ohtsuka, Mayumi Mochizuki, Mamoru Watanabe, Masayuki Hashiguchi, Takanori Kanai. Long-term effect of NUDT15 R139C on hematologic indices in inflammatory bowel disease patients treated with thiopurine. J. Gastroenterol. Hepatol.. 2019.05; 34 (10): 1751-1757. ( PubMed, DOI )

Chikatoshi Katada, Takahiro Horimatsu, Manabu Muto, Kiyohito Tanaka, Koji Matsuda, Mitsuhiro Fujishiro, Yutaka Saito, Kazuo Ohtsuka, Ichiro Oda, Masayuki Kato, Mitsuhiro Kida, Kiyonori Kobayashi, Shu Hoteya, Shinya Kodashima, Takahisa Matsuda, Hironori Yamamoto, Shomei Ryozawa, Ryuichi Iwakiri, Hiromu Kutsumi, Hiroaki Miyata, Mototsugu Kato, Ken Haruma, Kazuma Fujimoto, Naomi Uemura, Michio Kaminishi, Hisao Tajiri. Current status of esophageal endoscopy including the evaluation of smoking and alcohol consumption in Japan: an analysis based on the Japan endoscopy database. Esophagus. 2019.04; 16 (2): 174-179. ( PubMed, DOI )

Kaho Yamasaki, Kento Takenaka, Kazuo Ohtsuka. Laterally spreading tumor-like early cancer in ileum. Intern Med. 2019.03; 58 (6): 885-886. ( PubMed, DOI )

Yasuharu Maeda, Shin-Ei Kudo, Yuichi Mori, Masashi Misawa, Noriyuki Ogata, Seiko Sasanuma, Kunihiko Wakamura, Masahiro Oda, Kensaku Mori, Kazuo Ohtsuka. Fully automated diagnostic system with artificial intelligence using endocytoscopy to identify the presence of histologic inflammation associated with ulcerative colitis (with video). Gastrointest Endosc. 2019.02; 89 (2): 408-415. ( PubMed, DOI )

Kitazume Y, Fujioka T, Takenaka K, Oyama J, Ohtsuka K, Fujii T, Tateisi U. Crohn Disease: A 5-Point MR Enterocolonography Classification Using Enteroscopic Findings. AJR. American journal of roentgenology. 2018.11; 212 (1): 1-10. ( PubMed, DOI )

Niikura R, Yamada A, Fujishiro M, Tanaka K, Matsuda K, Saito Y, Ohtsuka K, Oda I, Katada C, Kato M, Kida M, Kobayashi K, Hoteya S, Horimatsu T, Kodashima S, Matsuda T, Muto M, Yamamoto H, Ryozawa S, Iwakiri R, Kutsumi H, Miyata H, Kato M, Haruma K, Fujimoto K, Uemura N, Kaminishi M, Shinozaki T, Tajiri H, Koike K. The Effects of Direct Oral Anticoagulants, Warfarin, Aspirin and Thienopyridine on the Performance of Immunochemical, Faecal, Occult Blood Tests. Digestion. 2018.11; 1-10. ( PubMed, DOI )

Ami Kawamoto, Sayaka Nagata, Sho Anzai, Junichi Takahashi, Mao Kawai, Minami Hama, Daichi Nogawa, Kohei Yamamoto, Reiko Kuno, Kohei Suzuki, Hiromichi Shimizu, Yui Hiraguri, Shiro Yui, Shigeru Ohshima, Kiichiro Tsuchiya, Tetsuya Nakamura, Kazuo Ohtsuka, Masanobu Kitagawa, Ryuichi Okamoto, Mamoru Watanabe. Ubiquitin D is up-regulated by synergy of Notch signalling and TNF-α in the inflamed intestinal epithelia of IBD patients. J Crohns Colitis. 2018.11; ( PubMed, DOI )

Hosoe N, Ohtsuka K, Endo Y, Naganuma M, Ogata N, Kuroki Y, Sasanuma S, Takabayashi K, Kudo SE, Takahashi H, Ogata H, Kanai T. Insertability comparison of passive bending single-balloon prototype versus standard single-balloon enteroscopy: a multicenter randomized non-blinded trial. Endoscopy international open. 2018.10; 6 (10): E1184-E1189. ( PubMed, DOI )

Suzuki K, Murano T, Shimizu H, Ito G, Nakata T, Fujii S, Ishibashi F, Kawamoto A, Anzai S, Kuno R, Kuwabara K, Takahashi J, Hama M, Nagata S, Hiraguri Y, Takenaka K, Yui S, Tsuchiya K, Nakamura T, Ohtsuka K, Watanabe M, Okamoto R. Single cell analysis of Crohn's disease patient-derived small intestinal organoids reveals disease activity-dependent modification of stem cell properties. Journal of gastroenterology. 2018.09; 53 (9): 1035-1047. ( PubMed, DOI )

Yuichi Mori, Shin-Ei Kudo, Masashi Misawa, Yutaka Saito, Hiroaki Ikematsu, Kinichi Hotta, Kazuo Ohtsuka, Fumihiko Urushibara, Shinichi Kataoka, Yushi Ogawa, Yasuharu Maeda, Kenichi Takeda, Hiroki Nakamura, Katsuro Ichimasa, Toyoki Kudo, Takemasa Hayashi, Kunihiko Wakamura, Fumio Ishida, Haruhiro Inoue, Hayato Itoh, Masahiro Oda, Kensaku Mori. Real-Time Use of Artificial Intelligence in Identification of Diminutive Polyps During Colonoscopy: A Prospective Study. Ann. Intern. Med. 2018.09; 169 (6): 357-366. ( PubMed, DOI )

Fumihiko Iwamoto, Katsuyoshi Matsuoka, Maiko Motobayashi, Kento Takenaka, Toru Kuno, Keisuke Tanaka, Yuya Tsukui, Shoji Kobayashi, Takashi Yoshida, Toshimitsu Fujii, Eiko Saito, Tatsuya Yamaguchi, Masakazu Nagahori, Tadashi Sato, Kazuo Ohtsuka, Nobuyuki Enomoto, Mamoru Watanabe. Prediction of disease activity of Crohn's disease through fecal calprotectin evaluated by balloon-assisted endoscopy. J. Gastroenterol. Hepatol.. 2018.06; ( PubMed, DOI )

Sasanuma S, Ohtsuka K, Kudo SE, Ogata N, Maeda Y, Misawa M, Mori Y, Kudo T, Hisayuki T, Wakamura K, Hayashi T, Katagiri A, Miyachi H, Baba T, Ishida F. Narrow band imaging efficiency in evaluation of mucosal healing/relapse of ulcerative colitis. Endoscopy international open. 2018.05; 6 (5): E518-E523. ( PubMed, DOI )

Yoshiki Wada, Masayoshi Fukuda, Kazuo Ohtsuka, Mamoru Watanabe, Yumiko Fukuma, Yoko Wada, Masahiro Wada. Efficacy of Endocuff-assisted colonoscopy in the detection of colorectal polyps. Endosc Int Open. 2018.04; 6 (4): E425-E431. ( PubMed, DOI )

Shintaro Akiyama, Masakazu Nagahori, Shinya Oooka, Mariko Negi, Takashi Ito, Kento Takenaka, Kazuo Ohtsuka, Mamoru Watanabe. Small intestinal obstruction due to the metastasis of intrahepatic cholangiocarcinoma: A case report. Medicine (Baltimore). 2018.03; 97 (12): e0190. ( PubMed, DOI )

Ogata N, Ohtsuka K, Sasanuma S, Ogawa M, Maeda Y, Ichimasa K, Mori Y, Misawa M, Kudo T, Hisayuki T, Hayashi T, Wakamura K, Miyachi H, Baba T, Ishida F, Kudo SE. White light-emitting contrast image capsule endoscopy for visualization of small intestine lesions: a pilot study. Endoscopy international open. 2018.03; 6 (3): E315-E321. ( PubMed, DOI )

Matsuda K, Tanaka K, Fujishiro M, Saito Y, Ohtsuka K, Oda I, Katada C, Kato M, Kida M, Kobayashi K, Hoteya S, Horimatsu T, Kodashima S, Matsuda T, Muto M, Yamamoto H, Ryozawa S, Iwakiri R, Kutsumi H, Miyata H, Kato M, Haruma K, Fujimoto K, Uemura N, Kaminishi M, Tajiri H. Design paper: Japan Endoscopy Database (JED): A prospective, large database project related to gastroenterological endoscopy in Japan. Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society. 2018.01; 30 (1): 5-19. ( PubMed, DOI )

Kodashima S, Tanaka K, Matsuda K, Fujishiro M, Saito Y, Ohtsuka K, Oda I, Katada C, Kato M, Kida M, Kobayashi K, Hoteya S, Horimatsu T, Matsuda T, Muto M, Yamamoto H, Ryozawa S, Iwakiri R, Kutsumi H, Miyata H, Kato M, Haruma K, Fujimoto K, Uemura N, Kaminishi M, Tajiri H. First progress report on the Japan Endoscopy Database project. Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society. 2018.01; 30 (1): 20-28. ( PubMed, DOI )

Kento Takenaka, Kazuo Ohtsuka, Yoshio Kitazume, Katsuyoshi Matsuoka, Masakazu Nagahori, Toshimitsu Fujii, Eiko Saito, Maiko Kimura, Tomoyuki Fujioka, Mamoru Watanabe. Utility of Magnetic Resonance Enterography For Small Bowel Endoscopic Healing in Patients With Crohn's Disease.[Epub ahead of print] Am. J. Gastroenterol.. 2017.12; ( PubMed, DOI )

Kento Takenaka, Kazuo Ohtsuka, Yoshio Kitazume, Katsuyoshi Matsuoka, Toshimitsu Fujii, Masakazu Nagahori, Maiko Kimura, Tomoyuki Fujioka, Akihiro Araki, Mamoru Watanabe. Magnetic resonance evaluation for small bowel strictures in Crohn's disease: comparison with balloon enteroscopy. J. Gastroenterol.. 2017.08; 52 (8): 879-888. ( PubMed, DOI )

Takenaka Kento, Ohtsuka Kazuo, Kitazume Yoshio, Matsuoka Katsuyoshi, Fujii Toshimitsu, Nagahori Masakazu, Kimura Maiko, Fujioka Tomoyuki, Araki Akihiro, Watanabe Mamoru. クローン病における小腸狭窄の磁気共鳴評価　バルーン小腸内視鏡検査との比較(Magnetic resonance evaluation for small bowel strictures in Crohn's disease: comparison with balloon enteroscopy) Journal of Gastroenterology. 2017.08; 52 (8): 879-888. ( ichushi )

Yamamoto H, Ogata H, Matsumoto T, Ohmiya N, Ohtsuka K, Watanabe K, Yano T, Matsui T, Higuchi K, Nakamura T, Fujimoto K. Clinical Practice Guideline for Enteroscopy. Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society. 2017.07; 29 (5): 519-546. ( PubMed, DOI )

Yasuharu Maeda, Kudo Shinei, Mori Yuichi, Misawa Masashi, Wakamura Kunihiko, Hayashi Seiko, Ogata Noriyuki, Takeda Kenichi, Kudo Toyoki, Hayashi Takemasa, Katagiri Atsushi, Ishida Fumio, Ohtsuka Kazuo, Oda Masahiro, Mori Kensaku. Artificial Intelligence for Endocytoscopy Provides Fully Automated Diagnosis of Histological Remission in Ulcerativ E. Coli Tis GASTROINTESTINAL ENDOSCOPY. 2017.05; 85 (5): AB248.

Akiyama S, Fujii T, Matsuoka K, Yusuke E, Negi M, Takenaka K, Nagahori M, Ohtsuka K, Isobe M, Watanabe M. Endoscopic features and genetic background of inflammatory bowel disease complicated with Takayasu arteritis. Journal of gastroenterology and hepatology. 2017.05; 32 (5): 1011-1017. ( PubMed, DOI )

Matsuoka K., Iwamoto F., Kimura M., Takenaka K., Fujii T., Nagahori M., Enomoto N., Ohtsuka K., Watanabe M.. Correlation of fecal calprotectin levels with endoscopic severity evaluated with balloon-assisted endoscopy in patients with Crohn's disease JOURNAL OF CROHNS & COLITIS. 2017.02; 11 S208.

Nagata Sayaka, Fujii Satoru, Suzuki Kohei, Kawamoto Ami, Ishibashi Fumiaki, Nakata Toru, Anzai Sho, Kuno-Ishii Reiko, Ito Go, Shimizu Hiromichi, Tsuchiya Kiichiro, Nakamura Tetsuya, Ootsuka Kazuo, Okamoto Ryuichi, Watanabe Mamoru. PGE2 Is a Robust Mediator of Chloride and Water Secretion by Human Intestinal Epithelial Cells INFLAMMATORY BOWEL DISEASES. 2017.02; 23 S91-S92.

Endo Y., Ohtsuka K., Yoshida A., Ueno F., Takenaka K., Watanabe M.. A novel small-caliber deep enteroscope can overcome technical difficulty of insertion in patients with Crohn's disease JOURNAL OF CROHNS & COLITIS. 2017.02; 11 S164-S165.

Toshiaki Watanabe, Yoichi Ajioka, Keiichi Mitsuyama, Kenji Watanabe, Hiroyuki Hanai, Hiroshi Nakase, Reiko Kunisaki, Keiji Matsuda, Ryuichi Iwakiri, Nobuyuki Hida, Shinji Tanaka, Yoshiaki Takeuchi, Kazuo Ohtsuka, Kazunari Murakami, Kiyonori Kobayashi, Yasushi Iwao, Masakazu Nagahori, Bunei Iizuka, Keisuke Hata, Masahiro Igarashi, Ichiro Hirata, Shin-Ei Kudo, Takayuki Matsumoto, Fumiaki Ueno, Gen Watanabe, Masahiro Ikegami, Yoko Ito, Koji Oba, Eisuke Inoue, Naoki Tomotsugu, Toru Takebayashi, Kenichi Sugihara, Yasuo Suzuki, Mamoru Watanabe, Toshifumi Hibi. Comparison of Targeted vs Random Biopsies for Surveillance of Ulcerative Colitis-Associated Colorectal Cancer. Gastroenterology. 2016.12; 151 (6): 1122-1130. ( PubMed, DOI )

Satoru Fujii, Kohei Suzuki, Ami Kawamoto, Fumiaki Ishibashi, Toru Nakata, Tatsuro Murano, Go Ito, Hiromichi Shimizu, Tomohiro Mizutani, Shigeru Oshima, Kiichiro Tsuchiya, Tetsuya Nakamura, Akihiro Araki, Kazuo Ohtsuka, Ryuichi Okamoto, Mamoru Watanabe. PGE2 is a direct and robust mediator of anion/fluid secretion by human intestinal epithelial cells. Sci Rep. 2016.11; 6 36795. ( PubMed, DOI )

Naoki Hosoe, Kenji Watanabe, Takako Miyazaki, Masaaki Shimatani, Takahiro Wakamatsu, Kazuichi Okazaki, Motohiro Esaki, Takayuki Matsumoto, Takayuki Abe, Takanori Kanai, Kazuo Ohtsuka, Mamoru Watanabe, Keiichi Ikeda, Hisao Tajiri, Naoki Ohmiya, Masanao Nakamura, Hidemi Goto, Tomoyuki Tsujikawa, Haruhiko Ogata. Evaluation of performance of the Omni mode for detecting video capsule endoscopy images: A multicenter randomized controlled trial. Endosc Int Open. 2016.08; 4 (8): E878-E882. ( PubMed, DOI )

Ryohei Hayashi, Kiichiro Tsuchiya, Keita Fukushima, Nobukatsu Horita, Shuji Hibiya, Keisuke Kitagaki, Mariko Negi, Eisaku Itoh, Takumi Akashi, Yoshinobu Eishi, Eriko Okada, Akihiro Araki, Kazuo Ohtsuka, Shinji Fukuda, Hiroshi Ohno, Ryuichi Okamoto, Tetsuya Nakamura, Shinji Tanaka, Kazuaki Chayama, Mamoru Watanabe. Reduced Human α-defensin 6 in Noninflamed Jejunal Tissue of Patients with Crohn's Disease. Inflamm. Bowel Dis.. 2016.05; 22 (5): 1119-1128. ( PubMed, DOI )

Kazuo Ohtsuka, Kento Takenaka, Yoshio Kitazume, Toshimitsu Fujii, Katsuyoshi Matsuoka, Maiko Kimura, Takashi Nagaishi, Mamoru Watanabe. Magnetic resonance enterography for the evaluation of the deep small intestine in Crohn's disease. Intest Res. 2016.04; 14 (2): 120-126. ( PubMed, DOI )

Kento Takenaka, Kazuo Ohtsuka, Yoshio Kitazume, Masakazu Nagahori, Toshimitsu Fujii, Eiko Saito, Tomoyuki Fujioka, Katsuyoshi Matsuoka, Makoto Naganuma, Mamoru Watanabe. Correlation of the Endoscopic and Magnetic Resonance Scoring Systems in the Deep Small Intestine in Crohn's Disease. Inflamm. Bowel Dis.. 2015.05; ( PubMed, DOI )

Yasuharu Maeda, Kazuo Ohtsuka, Shin-ei Kudo, Kunihiko Wakamura, Yuichi Mori, Noriyuki Ogata, Yoshiki Wada, Masashi Misawa, Akihiro Yamauchi, Seiko Hayashi, Toyoki Kudo, Takemasa Hayashi, Hideyuki Miyachi, Fuyuhiko Yamamura, Fumio Ishida, Haruhiro Inoue, Shigeharu Hamatani. Endocytoscopic narrow-band imaging efficiency for evaluation of inflammatory activity in ulcerative colitis. World J. Gastroenterol.. 2015.02; 21 (7): 2108-2115. ( PubMed, DOI )

Ulrike W Denzer, Thomas Rösch, Bilal Hoytat, Mohammed Abdel-Hamid, Xavier Hebuterne, Geoffroy Vanbiervielt, Jérôme Filippi, Haruiko Ogata, Naoki Hosoe, Kazuo Ohtsuka, Noriyuki Ogata, Keiichi Ikeda, Hiroyuki Aihara, Shin-Ei Kudo, Hisao Tajiri, Andras Treszl, Karl Wegscheider, Michel Greff, Jean-Francois Rey. Magnetically guided capsule versus conventional gastroscopy for upper abdominal complaints: a prospective blinded study. J. Clin. Gastroenterol.. 2015.02; 49 (2): 101-107. ( PubMed, DOI )

Xuan Li, Yun-Jia Zhao, Jun Dai, Xiao-Bo Li, Han-Bin Xue, Yao Zhang, Guang-Su Xiong, Kazuo Ohtsuka, Yun-Jie Gao, Qiang Liu, Yan Song, Jing-Yuan Fang, Zhi-Zheng Ge. Carbon dioxide insufflation improves the intubation depth and total enteroscopy rate in single-balloon enteroscopy: a randomised, controlled, double-blind trial. Gut. 2014.10; 63 (10): 1560-1565. ( PubMed, DOI )

Kento Takenaka, Kazuo Ohtsuka, Yoshio Kitazume, Masakazu Nagahori, Toshimitsu Fujii, Eiko Saito, Makoto Naganuma, Akihiro Araki, Mamoru Watanabe. Comparison of magnetic resonance and balloon enteroscopic examination of the small intestine in patients with Crohn's disease. Gastroenterology. 2014.08; 147 (2): 334-342.e3. ( PubMed )

Toshimitsu Fujii, Makoto Naganuma, Yoshio Kitazume, Eiko Saito, Masakazu Nagahori, Kazuo Ohtsuka, Mamoru Watanabe. Advancing magnetic resonance imaging in Crohn's disease. Digestion. 2014.01; 89 (1): 24-30. ( PubMed, DOI )

Eiko Saito, Masakazu Nagahori, Toshimitsu Fujii, Kazuo Ohtsuka, Mamoru Watanabe. Efficacy of salvage therapy and its effect on operative outcomes in patients with ulcerative colitis. Digestion. 2014.01; 89 (1): 55-60. ( PubMed, DOI )

Masakazu Nagahori, Toshimitsu Fujii, Eiko Saito, Kazuo Ohtsuka, Mamoru Watanabe. Biologics treatment for ulcerative colitis. Nihon Shokakibyo Gakkai Zasshi. 2013.11; 110 (11): 1909-1915. ( PubMed )

Kento Takenaka, Kazuo Ohtsuka, Ryuichi Okamoto. Balloon assisted enteroscopy and Magnetic resonance enterograpy for Small bowel Crohn’s disease. JDDW2021 2021.11.06

Shuji Hibiya, Kazuo Ohtsuka, Ryuichi Okamoto. Association between mucosal healing and surgery risk after endoscopic balloon dilatation for small intestinal stricture of Crohn's disease. JDDW2021 2021.11.06 神戸コンベンションセンター(兵庫)

土屋輝一郎、長堀正和、日比谷秀爾、竹中健人、河本亜美、清水寛路、藤井俊光、齊藤詠子、大塚和朗、渡辺　守、岡本隆一 . 【誌面発表】COVID-19蔓延下におけるスマートデバイスを用いたIBD病診連携に関する研究. 厚生労働科学研究費 難治性疾患政策研究事業 「難治性炎症性腸管障害に関する調査研究」令和3年度 第1回総会 2021.07.15 Web開催

Takashi Nagaishi, Daiki Yamada, Naoya Tsugawa, Taro Watabe, Eiko Saito, Masayoshi Fukuda, Ayako Arai, Kazuo Ohtsuka, Mamoru Watanabe. A case of villous atrophy with CCR4+ T cell infiltration in the small intestine.. UEGW2020 2020.10.10 Web開催

Toshimitsu Fujii, Shuji Hibiya, Chiaki Maeyashiki, Eiko Saito, Kento Takenaka, Maiko Motobayashi, Hiromichi Shimizu, Masakazu Nagahori, Kazuo Ohtsuka, Masayuki Kurosaki, Tsunehito Yauchi, Mamoru Watanabe. Intolerance to 5-aminosalicylate is a risk of poor prognosis in Ulcerative colitis patients.. ECCO2020 2020.02.14 Vienna（Austria）

Kento Takenaka, Kazuo Ohtsuka, Mamoru Watanabe. Small bowel endoscopic healing of Crohn’s disease treated with anti-TNF antibodies. JDDW2019 2019.11.21

Kento Takenaka, Kazuo Ohtsuka, Toshimitsu Fujii, Kohei Suzuki, Hiromichi Shimizu, Maiko Motobayashi, Shuji Hibiya, Eiko Saito, Masakazu Nagahori, Mamoru Watanabe. Small bowel endoscopic healing of Crohn’s disease treated with anti-TNF antibodies. The 7th Annual Meeting of Asian Organization for Crohn's and Colitis (AOCC 2019) 2019.06.15 台北

Eiko Saito, Kohei Suzuki, Shuuji Hibiya, Maiko Motobayashi, Kento Takenaka, Nobukatsu Horita, Hiromichi Shimizu, Michio Onizawa, Toshimitsu Fujii, Masakazu Nagahori, Kazuo Ohtsuka, Mamoru Watanabe. The clinical efficacy of ustekinumab (UST) in patients with Crohn’s disease (CD). AOCC2019 2019.06.15 台北

Kawamoto A, Nagata S, Anzai S, Takahashi J, Kawai M, Hama M, Nogawa D, Yamamoto K, Kuno R, Suzuki K, Shimizu H, Hiraguri Y, Yui S, Oshima S, Tsuchiya K, Nakamura T, Ohtsuka K, Kitagawa M, Okamoto R, Watanabe M. Synergy of Notch signalling and TNF-α in the inflamed intestinal epithelia of IBD patients leads to up-regulation of UBD, a ubiquitin-like protein. ECCO2019 2019.03.08 Copenhagen（Denmark）

Suzuki K, Shimizu H, Kawai M, Takahashi J, Anzai S, Kawamoto A, Nagata S, Hiraguri Y, Yui S, Tsuchiya K, Nakamura T, Ohtsuka K, Okamoto R, Watanabe M . UC-related and segment-specific properties of patientderived colonic organoids. ECCO2019 2019.03.07 Copenhagen（Denmark）

齊藤詠子、秋山慎太郎、鈴木康平、本林麻衣子、竹中健人、清水寛路、鬼澤道夫、藤井俊光、長堀正和、大塚和朗、渡辺　守. クローン病における抗TNF-α抗体二次無効時のウステキヌマブの治療成績について. 第9回日本炎症性腸疾患学会学術集会 2018.11.22 メルパルク京都（京都府京都市）

Kazuo Ohtsuka . State of the art for single balloon enteroscopy; Secrets of troubleshooting during insertion and therapeutic management. The6th GSTEC2018 2018.10.13 Seoul (Korea)

Suzuki K, Takahashi J, Hiraguri Y, Yui S, Shimizu H, Tsuchiya K, Nakamura T, Ohtsuka K, Okamoto R, Watanabe M. . Crohn’s disease patient-derived small intestinal organoids reveal diseasestatus related modification of stem cell properties.. 5th TERMIS World Congress 2018 2018.09.07 Kyoto（JAPAN）

Takenaka K, Ohtsuka K, Fujii T, Nagahori M, Saito E, Motobayashi M, Suzuki K, Watanabe M. Small bowel mucosal healing of Crohn’s disease treated with anti-TNF antibodies. FALKシンポジウム 2018.09.07 京都ホテルオークラ（京都府京都市）

Suzuki K, Murano T, Hiraguri Y, Takahashi J, Shimizu H,Anzai S, Kuwabara K, Kawamoto A, Ishibashi F, Yui S, Tsuchiya K, Nakamura T, Ohtsuka K, Watanabe M, Okamoto R... Crohn’s disease patient-derived small intestinal organoids reveal disease-status related modification of stem cell properties.. 5th TERMIS World Congress 2018 2018.09.06 Kyoto（JAPAN）

Kazuo Ohtsuka. Immunologocal Implication in the Development of IBD Medications. TASSID 3rd Academic Meeting of 2018 2018.09.01 Taipei（Taiwan）

Saito　E, Suzuki K, Shimizu H, Motobayashi M, Takenaka K, Onizawa M, Fujii T, Nagahori M, Ohtsuka K, Watanabe M. The clinical efficacy of switching cases between Infliximab(IFX) andAdalimumab(ADA) in patients with ulcerative colitis. AOCC2018 2018.06.22 Shanghai

Suzuki K, Kuwabara K, Takahashi J, Anzai S, Kuno R, Kawamoto A, Ishibashi F, Nagata S, Hiraguri Y, Yui S, Tsuchiya K, Nakamura T, Ohtsuka K, Okamoto R, Watanabe M.. Single-cell level analysis of organoids derived from CD patients reveals disease-status related modifications of small intestinal stem cells. DDW2018 2018.06.04 Washington D.C (USA）

Ohtsuka K, Takenaka K, Suzuki K, Fujii T, Nagahori M, Matsuoka K, Saito E, Katsukura N, Fukuda M, Araki A, Watanabe M. Usefulness of single-balloon enteroscopy: from a single center 990 experiences. DDW2018 2018.06.03 Washington D.C (USA）

Ohtsuka K. Live demonstrations. (Single-balloon Endoscopy). Endoscopy 2018 2018.04.08 Kuala Lumpur（Malaysia）

Ohtsuka K. Live demonstrations. (Single-balloon Endoscopy). Endoscopy 2018 2018.04.07 Kuala Lumpur（Malaysia）

Ohtsuka K. Balloon-assisted Endoscopy. Tips and Trick. Endoscopy 2018 2018.04.07 Kuala Lumpur（Malaysia）

Ohtsuka K. Tips of Enteroscopy -Single Balloon Endoscopy-. Taiwan Association for the Study of Small Intestinal Diseases (TASSID) Annual Meeting 2018 2018.03.25 Taipei（Taiwan）

Ohtsuka K. Small Bowel Bleeding-Japan experience. Taiwan Association for the Study of Small Intestinal Diseases (TASSID) Annual Meeting 2018 2018.03.24 Taipei（Taiwan）

T. Fujii Y. Kitazume K. Takenaka M. Kimura E. Saito K. Matsuoka M. Nagahori K. Ohtsuka M. Watanabe. Simplified MR enterocolonography Classification Based on Endoscopic Findings for Activity Assessment of Crohn’s Disease. UEGW2017 (欧州消化器病学会週間2017） 2017.11.01 Barcelona(Spain)

Takenaka K, Ohtsuka K, Kitazume Y, Fujii T, Matsuoka K, Kimura M, Nagahori M, Watanabe M. Utility of Magnetic Resonance Evaluation for Small Bowel Endoscopic Healing in Patients with Crohn’s Disease. UEGW2017 (欧州消化器病学会週間2017） 2017.10.30 Barcelona(Spain)

Takenaka K, Ohtsuka K, Kitazume Y, Matsuoka K, Fujii T, Nagahori M, Kimura M, Watanabe M.. Magnetic resonance enterography for small bowel mucosal healing in patients with Crohn’s disease.. APDW2017 2017.09.23 Hong Kong Convention and Exhibition Centre（香港）

Motobayashi M, Matsuoka K, Iwamoto F, Takenaka K, Fujii T, Nagahori M, Enomoto N, Ohtsuka K, Watanabe M. Correlation of Fecal Calprotectin Levels with Endoscopic Severity Evaluated with Balloon-assisted Endoscopy in Patients with Crohn’s Disease. . AOCC2017 2017.06.17 Seoul, Korea

Fujii T, Kitazume Y, Takenaka K, Kimura M, Matsuoka K, Nagahori M, Ohtsuka K, Watanabe M. The 5-point MR enterocolonography classification based on endoscopic findings for activity assessment of Crohn's disease. AOCC2017 2017.06.16 Seoul, Korea

Kento Takenaka, Kazuo Ohtsuka, Yoshio Kitazume, Katsuyoshi Matsuoka, Toshimitsu Fujii, Masakazu Nagahori, Maiko Kimura, Mamoru Watanabe. Magnetic resonance evaluation for small bowel endoscopic remission in patients with crohn’s disease.. AOCC2017 2017.06.15 Seoul, Korea

竹中健人、大塚和朗. 腹痛および皮疹を主訴に受診し バルーン内視鏡にて回腸病変を 認めた一例. 第103回日本紹介内視鏡学会関東支部例会 2016.12.18 シェーンバッハ・サボー（東京都千代田区）

Takenaka K, Ohtsuka K, Watanabe M. Magnetic resonance evaluation for small bowel strictures of Crohn’s disease: comparison with balloon enteroscopy. APDW2016 2016.11.05 kobe convention center

Toshimitsu Fujii, Kento Takenaka, Maiko Kimura, Katsuyoshi Matsuoka, Masakazu Nagahori, Kazuo Ohtsuka, Mamoru Watanabe. MR enterocolonography evaluation for small bowel strictures in patients with Crohn’s disease: comparison with balloon enteroscopy. UEGW2016 2016.10.18 VIENNA

Fujii T, Takenaka K, Kitazume Y, Kimura M, Matsuoka K, Nagahori M, Ohtsuka K, Watanabe M. MR enterocolonography can detect small bowel strictures and predict surgery in patients with Crohn’s disease: Comparison with balloon enteroscopy. APDW2016 2016.10.03 KOBE

Ohtsuka K, Takenaka K, Fujii T, Matsuoka K, Nagahori M, Kimura M, Fukuda M, Katsukura N, Watanabe M. Mucosal healing improves prognosis of endoscopic balloon dilatatiion for small intestinal strictures of Crohn's disease. AOCC2016 2016.07.09 Kyoto

Toshimitsu Fujii, Kento Takenaka, Maiko Kimura, Katsuyoshi Matsuoka, Masakazu Nagahori, Kazuo Ohtsuka, Mamoru Watanabe. The evaluation for small bowel strictures on MR enterocolonography in patients with Crohn’s disease. AOCC2016 2016.07.08 Kyoto

Kento Takenaka, Kazuo Ohtsuka, Yoshio Kitazume, Masakazu Nagahori, Katsuyoshi Matsuoka, Toshimitsu Fujii, Maiko Kimura, Tomoyuki Fujioka, Mamoru Watanabe. Enteroscopic and MR findings of small bowel in Crohn’s disease. AOCC2016 2016.07.07 Kyoto

Maiko Kimura, Katsuyoshi Matsuoka, Eiko Saito, Toshimitsu Fujii, Kento Takenaka, Masakazu Nagahori, Kazuo Ohtsuka, Mamoru Watanabe. Salvage therapy for corticosteroid-refractory ulcerative colitis patients.. AOCC2016 2016.07.07 Kyoto

Kazuo Ohtsuka, Kento Takenaka, Toshimitsu Fujii, Katsuyoshi Matsuoka, Masakazu Nagahori, Maiko Kimura, Masayoshi Fukuda, Nobuhiro Katsukura, Mamoru Watanabe. Mucosal healing improves prognosis of endoscopic balloon dilatation for small intestinal strictures of Crohn’s disease. AOCC2016 2016.07.07 Kyoto

Satoru Fujii, Kohei Suzuki, Ami Kawamoto, Fumiaki Ishibashi, Toru Nakata, Go Ito, Hiromichi Shimizu, Tomohiro Mizutani, Kiichiro Tsuchiya, Tetsuya Nakamura, Kazuo Ohtsuka, Ryuichi Okamoto, Mamoru Watanabe. In Vitro organoid model reveals PGF2 as a Robust Mediator of chloride & water secretion bt human intestinal epithelial cells. DDW2016 2016.05.23 San Diego

Kazuo Ohtsuka, Kento Takenaka, Toshimitsu Fujii, Katsuyoshi Matsuoka, Masakazu Nagahori, Kengo Nozaki, Masayoshi Fukuda, Mamoru Watanabe. Mucosal Healing is imoietant for better outcomes of endosdopic balloon dilatation for smakk intestinal stricture of crohn's disease. DDW2016 2016.05.23 San Diego

Kohei Suzuki, Satoru Fujii, Ami Kawamoto, Fumiaki Ishibashi, Toru Nakata, Go Ito, Hiromichi Shimizu, Kiichiro Tsuchiya, Tetsuya Nakamura, Kazuo Otsuka, Ryuichi Okamoto, Mamoru Watanabe. Single-cell level analysis reveals hoterogeneous expression of stem-cell specific genes in human small intestinal organoids. DDW2016 2016.05.21 San Diego

Kazuo Ohtsuka, Kento Takenaka, Mamoru Watanabe. 【Session 3: Imaging for follow up of IBD】Assessment of small intestinal lesions of Crohn’s disease. 第102回日本消化器病学会総会_The 5th International Forum 2016.04.21 Tokyo

Takenaka K, Ohtsuka K, Kitazume Y, Nagahori M, Matsuoka K, Fujii T, Kimura M, Fujioka T, Watanabe M. Enteroscopic and MR findings of small intestine in Crohn’s disease.. 7th APTC 2016.04.20 京王プラザホテル（新宿区）

K. Matsuoka, E. Saito, T. Fujii, K. Takenaka, F. Iwamoto, M. Kimura, M. Nagahori, K. Ohtsuka, M. Watanabe. Efficacy and safety of sequential rescue therapy with infliximab and tacrolimus in patients with corticosteroid-refractory Ulcerative Colitis. 11th Congress of ECCO - European Crohn‘s and Colitis Organisation 2016.03.19 Amsterdam

Fujii T,Takenaka K,Kitazume Y,Saito E,Matsuoka K,Nagahori M,Ohtsuka K,Watanabe M.. Modifying and validating endoscopic and magnetic resonance scoring systems for the deep small intestine in Crohn’s disease.. AOCC2015 2015.06.19 Beijing

Suzuki K,Fujii S,Nakata T,Kawamoto A,Ishibashi F,Segawa-Ohashi S,Mizutani T,Tsuchiya K,Ohtsuka K,Nakamura T,Okamoto R,Watanabe M.. Enrichment of Intestinal Stem Cells by the 3D-Culture of IBD Patient Derived Intestinal epithelium. AOCC2015 2015.06.19 Beijing

Ryohei Hayashi, Kiichiro Tsuchiya, Shuji Hibiya, Keita Fukushima, Nobukatsu Horita, Eriko Okada, Akihiro Araki, Kazuo Ohtsuka, Mamoru Watanabe. Human Alpha-Defensin 6 Regulated by the Cooperation of Beta-Catenin and ATOH1, Might Be the Pathogenesis of Crohn's Disease. DDW 2015 2015.05.18 Washington, D.C.

Toshimitsu Fujii, Kento Takenaka, Eiko Saito, Katsuyoshi Matsuoka, Masakazu Nagahori, Kazuo Ohtsuka, Mamoru Watanabe. Modifying and Validating Endoscopic and Magnetic Resonance Scoring Systems for the Deep Small Intestine in Crohn's Disease. DDW 2015 2015.05.17 Washington, D.C.

Matsuoka K, Saito E, Fujii T, Takenaka K, Nagahori M, Ohtsuka K, Watanabe M. The Ulcerative Colitis Endscopic Index of Severity (UCEIS) is useful to evaluate endoscopic improvement and to predict medium-term prognosis in Ulcerative Colitis patients treated with tacrolimus. 10th Congress of ECCO - Inflammatory Bowel Diseases 2015 2015.02.20 Barcelona

Hayashi R, Tsuchiya K, Hibiya S, Fukushima K, Horita N, Okada E, Araki A, Ohtsuka K, Watanabe M. Human alpha-defensin 6 regulated by both Atoh1 and beta-catenin might be the pathogenesis of Japanese Crohn's Disease. 10th Congress of ECCO - Inflammatory Bowel Diseases 2015 2015.02.20 Barcelona

Takenaka K, Ohtsuka K, Watanabe M. Enteroscopic and MR findings of small intestine in Crohn's disease. Japan Digesive Disease Weeks 2014 2014.10.26 Kobe

Takenaka K, Ohtsuka K, Kitazume Y, Nagahori M, Fujii T, Saito E, Watanabe M. Magnetic resonance enterocolonography can detect small intestinal active lesions in crohn's disease;comparison with balloon enteroscopy. UEGW2014 2014.10.20 Vienna

Fujii T, Naganuma M, Kitazume Y, Takenaka K, Nagahori M, Saito E, Ohtsuka K, Watanabe M. MR enterocolonography can identify patients who need additional treatment by predicting recurrence, hospitalization and surgey of Crohn's disease patients in remission. UEGW2014 2014.10.20 Vienna

Takenaka K, Otsuka K, Nagahori M, Fujii T, Saito E, Watanabe M. Comparison of Magnetic Resonance and Balloon Enteroscopic Examination of Deep Small Intestine in Patients with Crohn's Disease. The 2nd Annual Meeting of AOCC 2014.06.20 Seoul

Takenaka K, Otsuka K, Nagahori M, Fujii T, Saito E, Watanabe M. Comparing MR enterocolonography to enteroscopy in Crohn's disease, especially focusing on small intestinal findings. 9th congress of European Crohn's and Colitis Organisation 2014.02.20 Copenhagen