Personnel Information

写真a

KAWASUMI Miyuri


Job title

Assistant Professor

Campus Career 【 display / non-display

  • 2011.09
    -
    2014.08
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Advanced Therapeutic Sciences, Experimental Animal Model for Human Disease, Assistant Professor
  • 2011.09
    -
    2020.03
    Tokyo Medical and Dental University, Research University Promotion Organization, Research Administration Division, URA
  • 2020.04
    -
    Now
    Tokyo Medical and Dental University, , , Assistant Professor
 

Published Papers & Misc 【 display / non-display

  1. Hirate Y, Suzuki H, Kawasumi M, Takase HM, Igarashi H, Naquet P, Kanai Y, Kanai-Azuma M. Mouse Sox17 haploinsufficiency leads to female subfertility due to impaired implantation. Scientific reports. 2016.04; 6 24171. ( PubMed, DOI )

  2. Aiyama Y, Tsunekawa N, Kishi K, Kawasumi M, Suzuki H, Kanai-Azuma M, Kurohmaru M, Kanai Y. A Niche for GFRα1-Positive Spermatogonia in the Terminal Segments of the Seminiferous Tubules in Hamster Testes. Stem cells (Dayton, Ohio). 2015.09; 33 (9): 2811-24. ( PubMed, DOI )

  3. Shinomura M, Kishi K, Tomita A, Kawasumi M, Kanezashi H, Kuroda Y, Tsunekawa N, Ozawa A, Aiyama Y, Yoneda A, Suzuki H, Saito M, Picard JY, Kohno K, Kurohmaru M, Kanai-Azuma M, Kanai Y. A novel Amh-Treck transgenic mouse line allows toxin-dependent loss of supporting cells in gonads. Reproduction (Cambridge, England). 2014.12; 148 (6): H1-9. ( PubMed, DOI )

  4. Takahashi S, Lee J, Kohda T, Matsuzawa A, Kawasumi M, Kanai-Azuma M, Kaneko-Ishino T, Ishino F. Induction of the G2/M transition stabilizes haploid embryonic stem cells. Development (Cambridge, England). 2014.10; 141 (20): 3842-7. ( PubMed, DOI )

  5. Takada S, Sato T, Ito Y, Yamashita S, Kato T, Kawasumi M, Kanai-Azuma M, Igarashi A, Kato T, Tamano M, Asahara H. Targeted gene deletion of miRNAs in mice by TALEN system. PloS one. 2013; 8 (10): e76004. ( PubMed, DOI )

  6. Mori T, Miyamoto T, Yoshida H, Asakawa M, Kawasumi M, Kobayashi T, Morioka H, Chiba K, Toyama Y, Yoshimura A. IL-1β and TNFα-initiated IL-6-STAT3 pathway is critical in mediating inflammatory cytokines and RANKL expression in inflammatory arthritis. International immunology. 2011.11; 23 (11): 701-12. ( PubMed, DOI )

  7. Mori Tomoaki, Miyamoto Takeshi, Yoshida Hideyuki, Asakawa Mayoko, Kawasumi Miyuri, Kobayashi Takashi, Morioka Hideo, Chiba Kazuhiro, Toyama Yoshiaki, Yoshimura Akihiko. 炎症性関節炎においてIL-1βおよびTNFαにより開始されるIL-6-STAT3経路は炎症性サイトカインおよびRANKL発現を媒介するために必須である(IL-1β and TNFα-initiated IL-6-STAT3 pathway is critical in mediating inflammatory cytokines and RANKL expression in inflammatory arthritis) International Immunology. 2011.11; 23 (11): 701-712. ( ichushi )

  8. Miyamoto K, Yoshida S, Kawasumi M, Hashimoto K, Kimura T, Sato Y, Kobayashi T, Miyauchi Y, Hoshi H, Iwasaki R, Miyamoto H, Hao W, Morioka H, Chiba K, Kobayashi T, Yasuda H, Penninger JM, Toyama Y, Suda T, Miyamoto T. Osteoclasts are dispensable for hematopoietic stem cell maintenance and mobilization. The Journal of experimental medicine. 2011.10; 208 (11): 2175-81. ( PubMed, DOI )

  9. Nagamatsu G, Kosaka T, Kawasumi M, Kinoshita T, Takubo K, Akiyama H, Sudo T, Kobayashi T, Oya M, Suda T. A germ cell-specific gene, Prmt5, works in somatic cell reprogramming. The Journal of biological chemistry. 2011.03; 286 (12): 10641-8. ( PubMed, DOI )

  10. Nakaya Mako, Hamano Shinjiro, Kawasumi Miyuri, Yoshida Hiroki, Yoshimura Akihiko, Kobayashi Takashi. Leishmania major感染時のSOCS3過剰発現T細胞によるIL-4の異常な産生は病状を悪化させる(Aberrant IL-4 production by SOCS3-over-expressing T cells during infection with Leishmania major exacerbates disease manifestations) International Immunology. 2011.03; 23 (3): 195-202. ( ichushi )

  11. Li Z, Kawasumi M, Zhao B, Moisyadi S, Yang J. Transgenic over-expression of growth differentiation factor 11 propeptide in skeleton results in transformation of the seventh cervical vertebra into a thoracic vertebra. Molecular reproduction and development. 2010.11; 77 (11): 990-7. ( PubMed, DOI )

  12. Urschitz J, Kawasumi M, Owens J, Morozumi K, Yamashiro H, Stoytchev I, Marh J, Dee JA, Kawamoto K, Coates CJ, Kaminski JM, Pelczar P, Yanagimachi R, Moisyadi S. Helper-independent piggyBac plasmids for gene delivery approaches: strategies for avoiding potential genotoxic effects. Proceedings of the National Academy of Sciences of the United States of America. 2010.05; 107 (18): 8117-22. ( PubMed, DOI )

  13. Haueter S, Kawasumi M, Asner I, Brykczynska U, Cinelli P, Moisyadi S, Bürki K, Peters AH, Pelczar P. Genetic vasectomy-overexpression of Prm1-EGFP fusion protein in elongating spermatids causes dominant male sterility in mice. Genesis (New York, N.Y. : 2000). 2010.03; 48 (3): 151-60. ( PubMed, DOI )

  14. Kawasumi M, Unno Y, Matsuoka T, Nishiwaki M, Anzai M, Amano T, Mitani T, Kato H, Saeki K, Hosoi Y, Iritani A, Kishigami S, Matsumoto K. Abnormal DNA methylation of the Oct-4 enhancer region in cloned mouse embryos. Molecular reproduction and development. 2009.04; 76 (4): 342-50. ( PubMed, DOI )

  15. Tokoro Mikiko, Kawasumi Miyuri, Nagai Kohei, Ikegami Haruka, Amano Tomoko, Saeki Kazuhiro, Hosoi Yoshihiko, Iritani Akira, Matsumoto Kazuya. Proteome analysis of mouse preimplantation embryos BIOLOGY OF REPRODUCTION. 2008; 303.

  16. Kawasumi M, Anzai M, Takehara T, Mitani T, Kato H, Saeki K, Iritani A, Matsumoto K, Hosoi Y. Abnormal distribution of chromosomes in the first division of nuclear transferred mouse embryos. The Journal of reproduction and development. 2007.06; 53 (3): 615-22. ( PubMed, DOI )

  17. Kawasumi M., Unno Y., Nishiwaki M., Matsumoto K., Anzai M., Amano T., Mitani T., Kato H., Saeki K., Hosoi Y., Iritani A.. DNA methylation profiles of upstream elements of Oct-3/4 gene in in vitro fertilization (IVF) and somatic cell nuclear-transferred (SCNT) embryos REPRODUCTION FERTILITY AND DEVELOPMENT. 2007; 19 (1): 143.

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Conference Activities & Talks 【 display / non-display

  1. Transgenesis with transposase enzymes. 2008.06.20

  2. An improved method for producing transgenic mice by Intracytoplasmic sperm injection (ICSI) carrying large foreign DNA fragments (BAC). 2008.05.28