Katherine-Sofia Candray-Medina, Yu Nakagama, Masamichi Ito, Shun Nakagama, Evariste Tshibangu-Kabamba, Norihiko Takeda, Yuki Sugiura, Yuko Nitahara, Yu Michimuko-Nagahara, Natsuko Kaku, Yoko Onizuka, Carmen-Elena Arias, Maricela Mejia, Karla Alas, Susana Peña, Yasuhiro Maejima, Issei Komuro, Junko Nakajima-Shimada, Yasutoshi Kido. Differential cardiomyocyte transcriptomic remodeling during in vitro Trypanosoma cruzi infection using laboratory strains provides implications on pathogenic host responses. Trop Med Health. 2023.12; 51 (1): 68. ( PubMed, DOI )

Takahiko Sugihara, Haruhito A Uchida, Hajime Yoshifuji, Yasuhiro Maejima, Taio Naniwa, Yasuhiro Katsumata, Takahiro Okazaki, Jun Ishizaki, Yohko Murakawa, Noriyoshi Ogawa, Hiroaki Dobashi, Tetsuya Horita, Yoshiya Tanaka, Shunsuke Furuta, Tsutomu Takeuchi, Yoshinori Komagata, Yoshikazu Nakaoka, Masayoshi Harigai. Association between the patterns of large-vessel lesions and treatment outcomes in patients with large-vessel giant cell arteritis. Mod Rheumatol. 2023.11; 33 (6): 1145-1153. ( PubMed, DOI )

Shun Nakagama, Yasuhiro Maejima, Qintao Fan, Yuka Shiheido-Watanabe, Natsuko Tamura, Kensuke Ihara, Tetsuo Sasano. Endoplasmic Reticulum Selective Autophagy Alleviates Anthracycline-Induced Cardiotoxicity. JACC CardioOncol. 2023.10; 5 (5): 656-670. ( PubMed, DOI )

Yuka Shiheido-Watanabe, Yasuhiro Maejima, Shun Nakagama, Qintao Fan, Natsuko Tamura, Tetsuo Sasano. Porphyromonas gingivalis, a periodontal pathogen, impairs post-infarcted myocardium by inhibiting autophagosome-lysosome fusion. Int J Oral Sci. 2023.09; 15 (1): 42. ( PubMed, DOI )

Takeshi Yamamoto, Kazumasa Harada, Hideaki Yoshino, Masato Nakamura, Yoshinori Kobayashi, Tsutomu Yoshikawa, Yasuhiro Maejima, Toshiaki Otsuka, Ken Nagao, Morimasa Takayama. Impact of the COVID-19 pandemic on incidence and mortality of emergency cardiovascular diseases in Tokyo. J Cardiol. 2023.08; 82 (2): 134-139. ( PubMed, DOI )

Rikuta Hamaya, Taishi Yonetsu, Norio Aoyama, Yuka Shiheido-Watanabe, Akira Tashiro, Takayuki Niida, Mitsuaki Isobe, Yasuhiro Maejima, Takanori Iwata, Tetsuo Sasano. Contribution of periodontal health in cardiovascular secondary prevention: Analyses on hospitalized patients in cardiology units. J Clin Periodontol. 2023.06; 50 (6): 708-716. ( PubMed, DOI )

Yoshinori Kanno, Taishi Yonetsu, Norio Aoyama, Yuka Shiheido-Watanabe, Hiroshi Yoshikawa, Mari Ohmori, Akira Tashiro, Takayuki Niida, Yuji Matsuda, Makoto Araki, Eisuke Usui, Hiroto Hada, Tomoyuki Umemoto, Yasuhiro Maejima, Mitsuaki Isobe, Takanori Iwata, Tetsuo Sasano. Association between periodontal disease and pericardial adipose tissue in patients with cardiovascular disease. Am Heart J Plus. 2023.06; 30 100298. ( PubMed, DOI )

Natsuka Umezawa, Fumitaka Mizoguchi, Yasuhiro Maejima, Naoki Kimura, Hisanori Hasegawa, Tadashi Hosoya, Minoru Fujimoto, Hitoshi Kohsaka, Tetsuji Naka, Shinsuke Yasuda. Leucine-rich alpha-2 glycoprotein as a potential biomarker for large vessel vasculitides. Front Med (Lausanne). 2023.05; 10 1153883. ( PubMed, DOI )

Eisuke Usui, Eiki Nagaoka, Hiroshi Ikeda, Mari Ohmori, Susumu Tao, Taishi Yonetsu, Yasuhiro Maejima, Hirokuni Arai, Kisaki Amemiya, Yoshihiko Ikeda, Tetsuo Sasano. Fulminant myocarditis with COVID-19 infection having normal C-reactive protein and serial magnetic resonance follow-up. ESC Heart Fail. 2023.04; 10 (2): 1426-1630. ( PubMed, DOI )

Yasuhiro Maejima, Daniela Zablocki, Jihoon Nah, Junichi Sadoshima. The role of the Hippo pathway in autophagy in the heart. Cardiovasc Res. 2023.01; 118 (17): 3320-3330. ( PubMed, DOI )

Akira Tashiro, Taishi Yonetsu, Norio Aoyama, Yuka Shiheido-Watanabe, Takayuki Niida, Shinsuke Miyazaki, Yasuhiro Maejima, Masahiko Goya, Mitsuaki Isobe, Takanori Iwata, Tetsuo Sasano. Periodontitis was associated with worse clinical outcomes after catheter ablation for paroxysmal atrial fibrillation. Front Cardiovasc Med. 2023.01; 9 1061243. ( PubMed, DOI )

Qintao Fan, Yasuhiro Maejima, Lai Wei, Shun Nakagama, Yuka Shiheido-Watanabe, Tetsuo Sasano. The Pathophysiological Significance of "Mitochondrial Ejection" from Cells. Biomolecules. 2022.11; 12 (12): 1770. ( PubMed, DOI )

Sugihara Takahiko, Nakaoka Yoshikazu, Uchida Haruhito A., Yoshifuji Hajime, Maejima Yasuhiro, Watanabe Yoshiko, Amiya Eisuke, Tanemoto Kazuo, Miyata Tetsuro, Umezawa Natsuka, Manabe Yusuke, Ishizaki Jun, Shirai Tsuyoshi, Nagafuchi Hiroko, Hasegawa Hitoshi, Miyamae Takako, Niiro Hiroaki, Ito Shuichi, Ishii Tomonori, Isobe Mitsuaki, Harigai Masayoshi, Japan Research Committee of the Ministry of Health, Labour, and Welfare for Intractable Vasculitis(JPVAS). Establishing clinical remission criteria and the framework of a treat-to-target algorithm for Takayasu arteritis: Results of a Delphi exercise carried out by an expert panel of the Japan Research Committee of the Ministry of Health, Labour and Welfare for intractable vasculitis Modern Rheumatology. 2022.09; 32 (5): 930-937. ( 医中誌 )

Masataka Sano, Yasuhiro Maejima, Shun Nakagama, Yuka Shiheido-Watanabe, Natsuko Tamura, Kenzo Hirao, Mitsuaki Isobe, Tetsuo Sasano. Neutrophil extracellular traps-mediated Beclin-1 suppression aggravates atherosclerosis by inhibiting macrophage autophagy. Front Cell Dev Biol. 2022.07; 10 876147. ( PubMed, DOI )

Taku Fukushima, Taishi Yonetsu, Norio Aoyama, Akira Tashiro, Takayuki Niida, Yuka Shiheido-Watanabe, Yasuhiro Maejima, Mitsuaki Isobe, Takanori Iwata, Tetsuo Sasano. Effect of Periodontal Disease on Long-Term Outcomes After Percutaneous Coronary Intervention for De Novo Coronary Lesions in Non-Smokers. Circ J. 2022.04; 86 (5): 811-818. ( PubMed, DOI )

Keita Watanabe, Takashi Ashikaga, Yasuhiro Maejima, Susumu Tao, Mao Terui, Tetsuya Kishigami, Masakazu Kaneko, Ryota Nakajima, Shinichiro Okata, Tetsumin Lee, Tomoki Horie, Masashi Nagase, Giichi Nitta, Ryoichi Miyazaki, Sho Nagamine, Yasutoshi Nagata, Toshihiro Nozato, Masahiko Goya, Tetsuo Sasano. Case Report: Importance of MRI Examination in the Diagnosis and Evaluation of COVID-19 mRNA Vaccination Induced Myocarditis: Our Experience and Literature Review. Front Cardiovasc Med. 2022.04; 9 844626. ( PubMed, DOI )

Masanori Asakura, Shin Ito, Takahisa Yamada, Yoshihiko Saito, Kazuo Kimura, Akira Yamashina, Atsushi Hirayama, Youichi Kobayashi, Akihisa Hanatani, Mitsuru Tsujimoto, Satoshi Yasuda, Yukio Abe, Yorihiko Higashino, Yodo Tamaki, Hiroshi Sugino, Hiroyuki Niinuma, Yoshitaka Okuhara, Toshimi Koitabashi, Shin-Ichi Momomura, Kuniya Asai, Akihiro Nomura, Hiroya Kawai, Yasuhiro Satoh, Tsutomu Yoshikawa, Ken-Ichi Hirata, Yoshiaki Yokoi, Jun Tanaka, Yoshisato Shibata, Yasuhiro Maejima, Shunsuke Tamaki, Hiroyuki Kawata, Noriaki Iwahashi, Masatake Kobayashi, Yoshiharu Higuchi, Akiko Kada, Haruko Yamamoto, Masafumi Kitakaze. Efficacy and Safety of Early Initiation of Eplerenone Treatment in Patients with Acute Heart Failure (EARLIER trial): a multicentre, randomized, double-blind, placebo-controlled trial. Eur Heart J Cardiovasc Pharmacother. 2022.02; 8 (2): 108-117. ( PubMed, DOI )

Shun Nakagama, Katherine Candray, Tasuku Yamamoto, Yuta Tsugeno, Yu Nakagama, Yasutoshi Kido, Yuko Nitahara, Yasuhiro Maejima, Tetsuo Sasano. Inflammatory cardiomyopathy of possibly overlapping aetiology: a case posing treatment dilemma and potential association. ESC Heart Fail. 2022.02; 9 (1): 761-765. ( PubMed, DOI )

Yusuke Ito, Yasuhiro Maejima, Shun Nakagama, Yuka Shiheido-Watanabe, Natsuko Tamura, Tetsuo Sasano. Rivaroxaban, a Direct Oral Factor Xa Inhibitor, Attenuates Atherosclerosis by Alleviating Factor Xa-PAR2-Mediated Autophagy Suppression. JACC Basic Transl Sci. 2021.12; 6 (12): 964-980. ( PubMed, DOI )

Seiya Oba, Tadashi Hosoya, Miki Amamiya, Takahiro Mitsumura, Daisuke Kawata, Hirokazu Sasaki, Mari Kamiya, Akio Yamamoto, Takahiro Ando, Sho Shimada, Tsuyoshi Shirai, Tsukasa Okamoto, Tomoya Tateishi, Akira Endo, Junichi Aiboshi, Nobuyuki Nosaka, Hideo Yamanouchi, Toyomu Ugawa, Eiki Nagaoka, Keiji Oi, Susumu Tao, Yasuhiro Maejima, Yukie Tanaka, Kousuke Tanimoto, Hiroaki Takeuchi, Shuji Tohda, Akihiro Hirakawa, Tetsuo Sasano, Hirokuni Arai, Yasuhiro Otomo, Yasunari Miyazaki, Shinsuke Yasuda. Arterial and Venous Thrombosis Complicated in COVID-19: A Retrospective Single Center Analysis in Japan. Front Cardiovasc Med. 2021.11; 8 767074. ( PubMed, DOI )

Takahiko Sugihara, Yoshikazu Nakaoka, Haruhito A Uchida, Hajime Yoshifuji, Yasuhiro Maejima, Yoshiko Watanabe, Eisuke Amiya, Kazuo Tanemoto, Tetsuro Miyata, Natsuka Umezawa, Yusuke Manabe, Jun Ishizaki, Tsuyoshi Shirai, Hiroko Nagafuchi, Hitoshi Hasegawa, Takako Miyamae, Hiroaki Niiro, Shuichi Ito, Tomonori Ishii, Mitsuaki Isobe, Masayoshi Harigai. Establishing Clinical Remission Criteria and the Framework of a Treat-To-Target Algorithm for Takayasu arteritis: Results of a Delphi Exercise Carried out by an Expert Panel of the Japan Research Committee of the Ministry of Health, Labour, and Welfare for intractable vasculitis. Mod Rheumatol. 2021.11; 32 (5): 930-937. ( PubMed, DOI )

Natsuko Tamura, Yasuhiro Maejima, Yuka Shiheido-Watanabe, Shun Nakagama, Mitsuaki Isobe, Tetsuo Sasano. Plasma apolipopotein C-2 elevation is associated with Takayasu arteritis. Sci Rep. 2021.09; 11 (1): 18958. ( PubMed, DOI )

Yanbin Chen, Yasuhiro Maejima, Akihiro Shirakabe, Takanobu Yamamoto, Yoshiyuki Ikeda, Junichi Sadoshima, Peiyong Zhai. Ser9 phosphorylation of GSK-3β promotes aging in the heart through suppression of autophagy. J Cardiovasc Aging. 2021.08; 1 9. ( PubMed, DOI )

Yuka Shiheido-Watanabe, Yasuhiro Maejima, Takeshi Kasama, Natsuko Tamura, Shun Nakagama, Yusuke Ito, Kenzo Hirao, Mitsuaki Isobe, Tetsuo Sasano. Linagliptin, a Xanthine-based Dipeptidyl Peptidase-4 Inhibitor, Ameliorates Experimental Autoimmune Myocarditis. JACC Basic Transl Sci. 2021.06; 6 (6): 527-542. ( PubMed, DOI )

Mitsuaki Isobe, Yasuhiro Maejima, Mike Saji, Ukihide Tateishi. F-fluorodeoxyglucose-positron emission tomography for detecting inflammation under tocilizumab treatment. J Cardiol. 2021.05; 77 (5): 539-544. ( PubMed, DOI )

Masataka Kamiya, Kuniya Asai, Yasuhiro Maejima, Akihiro Shirakabe, Koji Murai, Satsuki Noma, Hidenori Komiyama, Naoki Sato, Kyoichi Mizuno, Wataru Shimizu. Beta3-adrenergic Receptor Agonist Prevents Diastolic Dysfunction in an Angiotensin II-Induced Cardiomyopathy Mouse Model. J Pharmacol Exp Ther. 2021.03; 376 (3): 473-481. ( PubMed, DOI )

Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Maejima Y, et al.. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 2021.02; 17 (1): 1-382. ( PubMed, DOI )

Yoshikazu Nakaoka, Mitsuaki Isobe, Yoshiya Tanaka, Tomonori Ishii, Seido Ooka, Hiroaki Niiro, Naoto Tamura, Shogo Banno, Hajime Yoshifuji, Yasushi Sakata, Atsushi Kawakami, Tatsuya Atsumi, Shunsuke Furuta, Hitoshi Kohsaka, Katsuya Suzuki, Ryoki Hara, Yasuhiro Maejima, Hiroshi Tsukamoto, Yoshinari Takasaki, Katsuhisa Yamashita, Norihiro Okada, Shinji Yamakido, Syuji Takei, Shumpei Yokota, Norihiro Nishimoto. Long-term efficacy and safety of tocilizumab in refractory Takayasu arteritis: final results of the randomized controlled phase 3 TAKT study. Rheumatology (Oxford). 2020.09; 59 (9): 2427-2434. ( PubMed, DOI )

Daisuke Tezuka, Yasuhiro Maejima, Tetsuo Sasano, Mitsuaki Isobe . Diagnostic Role and Feasibility of 18F-FDG PET for Assessing Takayasu Arteritis: Diagnostic Efficacy of Quantifying 18F-FDG Uptake Annals of Nuclear Cardiology. 2020.08; 6 (1): 74-80. ( 医中誌 )

Yuji Matsuda, Takashi Ashikaga, Taro Sasaoka, Yu Hatano, Tomoyuki Umemoto, Tetsumin Lee, Taishi Yonetsu, Yasuhiro Maejima, Tetsuo Sasano. Comparison of Neointimal Response between Durable-Polymer Everolimus-Eluting Stent and Bioabsorbable-Polymer Everolimus-Eluting Stent for Severely Calcified Lesions Requiring Rotational Atherectomy. Int Heart J. 2020.07; 61 (4): 665-672. ( PubMed, DOI )

Yuji Matsuda, Takashi Ashikaga, Taro Sasaoka, Yu Hatano, Tomoyuki Umemoto, Tetsumin Lee, Taishi Yonetsu, Yasuhiro Maejima, Tetsuo Sasano. Ostial left circumflex lesion with calcified nodule successfully treated with excimer laser coronary atherectomy and drug-coated balloon. J Cardiol Cases. 2020.07; 22 (1): 32-35. ( PubMed, DOI )

Matsuda Yuji, Ashikaga Takashi, Sasaoka Taro, Hatano Yu, Umemoto Tomoyuki, Lee Tetsumin, Yonetsu Taishi, Maejima Yasuhiro, Sasano Tetsuo. エキシマレーザー冠動脈形成術と薬剤被覆バルーンで治療した左回旋枝入口部の結節性石灰化病変(Ostial left circumflex lesion with calcified nodule successfully treated with excimer laser coronary atherectomy and drug-coated balloon) Journal of Cardiology Cases. 2020.07; 22 (1): 32-35. ( 医中誌 )

Takahiko Sugihara, Hitoshi Hasegawa, Haruhito A Uchida, Hajime Yoshifuji, Yoshiko Watanabe, Eisuke Amiya, Yasuhiro Maejima, Masanori Konishi, Yohko Murakawa, Noriyoshi Ogawa, Shunsuke Furuta, Yasuhiro Katsumata, Yoshinori Komagata, Taio Naniwa, Takahiro Okazaki, Yoshiya Tanaka, Tsutomu Takeuchi, Yoshikazu Nakaoka, Yoshihiro Arimura, Masayoshi Harigai, Mitsuaki Isobe, . Associated factors of poor treatment outcomes in patients with giant cell arteritis: clinical implication of large vessel lesions. Arthritis Res. Ther.. 2020.04; 22 (1): 72. ( PubMed, DOI )

Yasuhiro Maejima. The critical roles of protein quality control systems in the pathogenesis of heart failure. J Cardiol. 2020.03; 75 (3): 219-227. ( PubMed, DOI )

Yasuhiro Maejima. SGLT2 Inhibitors Play a Salutary Role in Heart Failure via Modulation of the Mitochondrial Function. Front Cardiovasc Med. 2020.01; 6 186. ( PubMed, DOI )

Mitsuaki Isobe, Koichi Amano, Yoshihiro Arimura, Akihiro Ishizu, Shuichi Ito, Shinya Kaname, Shigeto Kobayashi, Yoshinori Komagata, Issei Komuro, Kimihiro Komori, Kei Takahashi, Kazuo Tanemoto, Hitoshi Hasegawa, Masayoshi Harigai, Shouichi Fujimoto, Tatsuhiko Miyazaki, Tetsuro Miyata, Hidehiro Yamada, Akitoshi Yoshida, Takashi Wada, Yoshinori Inoue, Haruhito A Uchida, Hideki Ota, Takahiro Okazaki, Mitsuho Onimaru, Tamihiro Kawakami, Reiko Kinouchi, Atsushi Kurata, Hisanori Kosuge, Ken-Ei Sada, Kunihiro Shigematsu, Eiichi Suematsu, Eijun Sueyoshi, Takahiko Sugihara, Hitoshi Sugiyama, Mitsuhiro Takeno, Naoto Tamura, Michi Tsutsumino, Hiroaki Dobashi, Yoshikazu Nakaoka, Kenji Nagasaka, Yasuhiro Maejima, Hajime Yoshifuji, Yoshiko Watanabe, Shoichi Ozaki, Takeshi Kimura, Hiroshi Shigematsu, Keiko Yamauchi-Takihara, Toyoaki Murohara, Shin-Ichi Momomura, . JCS 2017 Guideline on Management of Vasculitis Syndrome　- Digest Version. Circ J. 2020.01; 84 (2): 299-359. ( PubMed, DOI )

Shun Nakagama, Taishi Yonetsu, Shinya Shiohira, Yuji Matsuda, Taro Sasaoka, Yu Hatano, Atsuhiko Yagishita, Tomoyuki Umemoto, Shingo Maeda, Takanobu Yamamoto, Tomohiro Yoneyama, Yoshio Kitazume, Yoshihide Takahashi, Yasuhiro Maejima, Mihoko Kawabata, Masahiko Goya, Takashi Ashikaga, Hirokuni Arai, Kenzo Hirao. Exertional syncope caused by myocardial ischemia due to arterial steal syndrome in left internal mammary artery graft. Coron. Artery Dis.. 2019.09; 30 (6): 469-470. ( PubMed, DOI )

Tsutsui Hiroyuki, Momomura Shin-ichi, Masuyama Tohru, Saito Yoshihiko, Komuro Issei, Murohara Toyoaki, Kinugawa Shintaro, Oba Koji, Sato Norihiro, Yasumura Yoshio, Hiramitsu Shinya, Satou Yukihito, Inomata Takayuki, Onishi Katsuya, Sakata Yasushi, Mizuno Kyoichi, Sunagawa Kenji, Ogawa Hisao, Isobe Mitsuaki, Daida Hiroyuki, Kurabayashi Masahiko, Kinugawa Shintaro, Kohya Tetsuro, Ogawa Yuji, Itoh Naofumi, Kakinoki Shigeo, Aoki Kenji, Tsuchida Akihito, Ito Hiroshi, Yamaguchi Osamu, Eki Yutaka, Toyoda Shigeru, Nakano Akihiko, Koitabashi Norimichi, Muramatsu Toshihiro, Nakahara Hideo, Tanaka Hiroyuki, Yamashina Akira, Takasu Kiyoshi, Maejima Yasuhiro, Momiyama Yukihiko, Nakamura Iwao, Kida Keisuke, Naruke Takashi, Takenobu Hideshi, Minamino Tohru, Nakamura Masahiko, Ikeda Masatoshi, Ashida Kazuhiro, Takahashi Shigekiyo, Minatoguchi Shinya, Suwa Satoru, Satoh Hiroshi, Izawa Hideo, Fukuta Hidekatsu, Tsuboi Naoya, Uzui Hiroyasu, Wada Atsuyuki, Kimura Takeshi, Takenaka Ken, Kato Takao, Okutsu Masaaki, Ohtani Tomohito, Hasegawa Shinji, Anzai Toshihisa, Fujii Kenshi, Shiojima Ichiro, Yasaka Yoshinori, Masuyama Tohru, Hirata Ken-ichi, Saito Yoshihiko, Akasaka Takashi, Ito Hiroshi, Kihara Yasuki, Tamura Ritsu, Teragawa Hiroki, Yasuda Kotaro, Okuhara Koichiro, Karashima Eiji, Sata Masataka, Ota Akira, Noma Takahisa, Suzuki Jun, Watanabe Kouki, Kitaoka Hiroaki, Matsukawa Ryuichi, Yoshihiro Takeshi, Tanaka Nobuhide, Ozumi Kiyoshi, Takahashi Masaru, Maemura Koji, Atsuchi Nobuhiko. Tolerability, Efficacy, and Safety of Bisoprolol vs. Carvedilol in Japanese Patients With Heart Failure and Reduced Ejection Fraction - The CIBIS-J Trial - CIRCULATION JOURNAL. 2019.06; 83 (6): 1269-+. ( DOI )

Toshiro Saito, Jihoon Nah, Shin-Ichi Oka, Risa Mukai, Yoshiya Monden, Yasuhiro Maejima, Yoshiyuki Ikeda, Sebastiano Sciarretta, Tong Liu, Hong Li, Erdene Baljinnyam, Diego Fraidenraich, Luke Fritzky, Peiyong Zhai, Shizuko Ichinose, Mitsuaki Isobe, Chiao-Po Hsu, Mondira Kundu, Junichi Sadoshima. An alternative mitophagy pathway mediated by Rab9 protects the heart against ischemia. J. Clin. Invest.. 2019.02; 129 (2): 802-819. ( PubMed, DOI )

Hiroaki Kikuchi, Emi Sasaki, Naohiro Nomura, Takayasu Mori, Yoji Andrew Minamishima, Yuki Yoshizaki, Naohiro Takahashi, Taisuke Furusho, Yohei Arai, Shintaro Mandai, Takahiro Yamashita, Fumiaki Ando, Yasuhiro Maejima, Kiyoshi Isobe, Tomokazu Okado, Tatemitsu Rai, Shinichi Uchida, Eisei Sohara. Failure to sense energy depletion may be a novel therapeutic target in chronic kidney disease. Kidney Int.. 2019.01; 95 (1): 123-137. ( PubMed, DOI )

Junichi Tsuchiya, Daisuke Tezuka, Yasuhiro Maejima, Hyeyeol Bae, Takumi Oshima, Tomohiro Yoneyama, Kenzo Hirao, Mitsuaki Isobe, Ukihide Tateishi . Takayasu arteritis: clinical importance of extra-vessel uptake on FDG PET/CT European Journal of Hybrid Imaging. 2019; 3 12.

Takanobu Yamamoto, Sawako Yada, Yuji Matsuda, Hirofumi Otani, Shunji Yoshikawa, Taro Sasaoka, Yu Hatano, Tomoyuki Umemoto, Daisuke Ueshima, Yasuhiro Maejima, Kenzo Hirao, Takashi Ashikaga. A Novel Rotablator Technique (Low-Speed following High-Speed Rotational Atherectomy) Can Achieve Larger Lumen Gain: Evaluation Using Optimal Frequency Domain Imaging. J Interv Cardiol. 2019; 2019 9282876. ( PubMed, DOI )

Chikashi Terao, Hajime Yoshifuji, Takayoshi Matsumura, Taeko K Naruse, Tomonori Ishii, Yoshikazu Nakaoka, Yohei Kirino, Keitaro Matsuo, Tomoki Origuchi, Masakazu Shimizu, Yasuhiro Maejima, Eisuke Amiya, Natsuko Tamura, Takahisa Kawaguchi, Meiko Takahashi, Kazuya Setoh, Koichiro Ohmura, Ryu Watanabe, Tetsuya Horita, Tatsuya Atsumi, Mitsuru Matsukura, Tetsuro Miyata, Yuta Kochi, Toshio Suda, Kazuo Tanemoto, Akira Meguro, Yukinori Okada, Akiyoshi Ogimoto, Motohisa Yamamoto, Hiroki Takahashi, Shingo Nakayamada, Kazuyoshi Saito, Masataka Kuwana, Nobuhisa Mizuki, Yasuharu Tabara, Atsuhisa Ueda, Issei Komuro, Akinori Kimura, Mitsuaki Isobe, Tsuneyo Mimori, Fumihiko Matsuda. Genetic determinants and an epistasis of LILRA3 and HLA-B*52 in Takayasu arteritis Proc. Natl. Acad. Sci. U.S.A.. 2018.11; 115 (51): 13045-13050. ( PubMed, DOI )

Natsuko Tamura, Yasuhiro Maejima, Takayoshi Matsumura, Rick B Vega, Eisuke Amiya, Yusuke Ito, Yuka Shiheido-Watanabe, Takashi Ashikaga, Issei Komuro, Daniel P Kelly, Kenzo Hirao, Mitsuaki Isobe. Single-Nucleotide Polymorphism of the MLX Gene Is Associated With Takayasu Arteritis Circ Genom Precis Med. 2018.10; 11 (10): e002296. ( PubMed, DOI )

Yasuhiro Maejima. Everything in Moderation. Int Heart J. 2018.10; 59 (5): 917-919. ( PubMed, DOI )

Daisuke Ueshima, Shunji Yoshikawa, Taro Sasaoka, Yu Hatano, Ken Kurihara, Yasuhiro Maejima, Mitsuaki Isobe, Takashi Ashikaga. The Hypercholesterolemia Paradox in Percutaneous Coronary Intervention: An Analysis of a Multicenter PCI Registry. Intern. Med.. 2018.09; 58 (3): 345-353. ( PubMed, DOI )

Yuji Matsuda, Takashi Ashikaga, Taro Sasaoka, Yu Hatano, Tomoyuki Umemoto, Takanobu Yamamoto, Yasuhiro Maejima, Kenzo Hirao. Effectiveness of the proximal optimization technique for longitudinal stent elongation caused by post-balloon dilatation. Journal of Interventional Cardiology. 2018.07; 31 (5): 624-631. ( PubMed, DOI )

Daisuke Ueshima, Shunji Yoshikawa, Taro Sasaoka, Yu Hatano, Ken Kurihara, Yasuhiro Maejima, Mitsuaki Isobe, Takashi Ashikaga. Obesity paradox in the era of percutaneous coronary intervention with 2nd-generation drug-eluting stents: an analysis of a multicenter PCI registry. Heart Vessels. 2018.07; 34 (2): 218-226. ( PubMed, DOI )

Yusuke Ito, Yasuhiro Maejima, Natsuko Tamura, Yuka Shiheido-Watanabe, Masanori Konishi, Takashi Ashikaga, Kenzo Hirao, Mitsuaki Isobe. Synergistic effects of HMG-CoA reductase inhibitor and angiotensin II receptor blocker on load-induced heart failure. FEBS Open Bio. 2018.05; 8 (5): 799-816. ( PubMed, DOI )

Sebastiano Sciarretta, Yasuhiro Maejima, Daniela Zablocki, Junichi Sadoshima. The Role of Autophagy in the Heart. Annu. Rev. Physiol.. 2018.02; 80 1-26. ( PubMed, DOI )

Taku Fukushima, Takashi Ashikaga, Shunji Yoshikawa, Yu Hatano, Daisuke Ueshima, Takanobu Yamamoto, Yasuhiro Maejima, Mitsuaki Isobe. Effect of drug-coated balloon on stent restenosis, neointimal proliferation, and coronary dissection: an optical coherence tomography analysis. Coron. Artery Dis.. 2017.09; 29 (1): 39-45. ( PubMed, DOI )

Natsuko Tamura, Yasuhiro Maejima, Daisuke Tezuka, Chisato Takamura, Shunji Yoshikawa, Takashi Ashikaga, Kenzo Hirao, Mitsuaki Isobe. Profiles of serum cytokine levels in Takayasu arteritis patients: Potential utility as biomarkers for monitoring disease activity. J Cardiol. 2017.09; 70 (3): 278-285. ( PubMed, DOI )

Anindita Das, Flávio Reis, Yasuhiro Maejima, Zhiyou Cai, Jun Ren. mTOR Signaling in Cardiometabolic Disease, Cancer, and Aging. Oxid Med Cell Longev. 2017.07; 2017 6018675. ( PubMed, DOI )

Ueshima Daisuke, Ashikaga Takashi, Yoshikawa Shunji, Sasaoka Taro, Hatano Yu, Kurihara Ken, Maejima Yasuhiro, Isobe Mitsuaki. Effect of over-2-year dual antiplatelet therapy on the rate of major adverse cardiac and cerebral events for everolimus-eluting stent implantation: The landmark analysis from Tokyo-MD PCI registry Journal of Cardiology. 2017.06; 69 (5-6): 815-822. ( 医中誌 )

Ohigashi Hirokazu, Tamura Natsuko, Ebana Yusuke, Harigai Masayoshi, Maejima Yasuhiro, Ashikaga Takashi, Isobe Mitsuaki. グルココルチコイド不応性の難治性高安動脈炎患者に対する免疫抑制剤および生物学的製剤の効果(Effects of immunosuppressive and biological agents on refractory Takayasu arteritis patients unresponsive to glucocorticoid treatment) Journal of Cardiology. 2017.06; 69 (5-6): 774-778. ( 医中誌 )

Ryo Watanabe, Jun-Ichi Suzuki, Kouji Wakayama, Yasuhiro Maejima, Munehisa Shimamura, Hiroshi Koriyama, Hironori Nakagami, Hidetoshi Kumagai, Yuichi Ikeda, Hiroshi Akazawa, Ryuichi Morishita, Issei Komuro, Mitsuaki Isobe. A peptide vaccine targeting angiotensin II attenuates the cardiac dysfunction induced by myocardial infarction. Sci Rep. 2017.03; 7 43920. ( PubMed, DOI )

Shunsuke Hirose, Takashi Ashikaga, Yu Hatano, Shunji Yoshikawa, Taro Sasaoka, Yasuhiro Maejima, Mitsuaki Isobe. Treatment of in-stent restenosis with excimer laser coronary angioplasty: benefits over scoring balloon angioplasty alone. Lasers Med Sci. 2016.11; 31 (8): 1691-1696. ( PubMed, DOI )

Yuka Shiheido, Yasuhiro Maejima, Jun-Ichi Suzuki, Norio Aoyama, Makoto Kaneko, Ryo Watanabe, Yuriko Sakamaki, Kouji Wakayama, Yuichi Ikeda, Hiroshi Akazawa, Shizuko Ichinose, Issei Komuro, Yuichi Izumi, Mitsuaki Isobe. Porphyromonas gingivalis, a periodontal pathogen, enhances myocardial vulnerability, thereby promoting post-infarct cardiac rupture. J Mol Cell Cardiol. 2016.10; 99 123-137. ( PubMed, DOI )

Daisuke Ueshima, Takashi Ashikaga, Shunji Yoshikawa, Taro Sasaoka, Yu Hatano, Ken Kurihara, Yasuhiro Maejima, Mitsuaki Isobe. Effect of over-2-year dual antiplatelet therapy on the rate of major adverse cardiac and cerebral events for everolimus-eluting stent implantation: The landmark analysis from Tokyo-MD PCI registry. J Cardiol. 2016.09; 69 (6): 815-822. ( PubMed, DOI )

Hirokazu Ohigashi, Natsuko Tamura, Yusuke Ebana, Masayoshi Harigai, Yasuhiro Maejima, Takashi Ashikaga, Mitsuaki Isobe. Effects of immunosuppressive and biological agents on refractory Takayasu arteritis patients unresponsive to glucocorticoid treatment. J Cardiol. 2016.08; 69 (5): 774-778. ( PubMed, DOI )

Shirakabe A, Zhai P, Ikeda Y, Saito T, Maejima Y, Hsu CP, Nomura M, Egashira K, Levine B, Sadoshima J. Response by Shirakabe et al to Letter Regarding Article, "Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure Overload-Induced Mitochondrial Dysfunction and Heart Failure". Circulation. 2016.08; 134 (6): e75-6. ( PubMed, DOI )

Yasuhiro Maejima, Mitsuaki Isobe, Junichi Sadoshima. Regulation of autophagy by Beclin 1 in the heart. J. Mol. Cell. Cardiol.. 2016.06; 95 19-25. ( PubMed, DOI )

Daisuke Tezuka, Jun-ichi Suzuki, Hisanori Kosuge, Norio Aoyama, Yuichi Izumi, Shunji Yoshikawa, Yasuhiro Maejima, Takashi Ashikaga, Kenzo Hirao, Mitsuaki Isobe. Deteriorated clinical outcome in coronary artery disease patients with a high prevalence of Porphyromonas gingivalis infection IJC Metabolic & Endocrine. 2016.05; 11 7-12. ( DOI )

Michinari Nakamura, Peiyong Zhai, Dominic P Del Re, Yasuhiro Maejima, Junichi Sadoshima. Mst1-mediated phosphorylation of Bcl-xL is required for myocardial reperfusion injury. JCI Insight. 2016.04; 1 (5): ( PubMed, DOI )

Akihiro Shirakabe, Peiyong Zhai, Yoshiyuki Ikeda, Toshiro Saito, Yasuhiro Maejima, Chiao-Po Hsu, Masatoshi Nomura, Kensuke Egashira, Beth Levine, Junichi Sadoshima. Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure-Overload-Induced Mitochondrial Dysfunction and Heart Failure. Circulation. 2016.02; ( PubMed, DOI )

Michiko Ito, Yasuhiro Maejima, Shizuka Okazaki, Mitsuaki Isobe, Hidehisa Saeki. Generalized pustular psoriasis associated with Turner syndrome and dilated cardiomyopathy. J. Dermatol.. 2016.02; 43 (7): 829-30. ( PubMed, DOI )

Chisato Takamura, Jun-Ichi Suzuki, Masahito Ogawa, Ryo Watanabe, Yuko Tada, Yasuhiro Maejima, Hiroshi Akazawa, Issei Komuro, Mitsuaki Isobe. Suppression of murine autoimmune myocarditis achieved with direct renin inhibition. J Cardiol. 2015.10; 68 (3): 253-60. ( PubMed, DOI )

Daisuke Ueshima, Takashi Ashikaga, Tsukasa Shimura, Yu Hatano, Taro Sasaoka, Ken Kurihara, Shunji Yoshikawa, Yasuhiro Maejima, Mitsuaki Isobe. Popliteal Retrograde Approach is Effective and Safe for Superficial Femoral Artery Chronic Total Occlusion. Ann Vasc Dis. 2015.08; 8 (3): 220-226. ( PubMed, DOI )

Chikashi Terao, Takayoshi Matsumura, Hajime Yoshifuji, Yohei Kirino, Yasuhiro Maejima, Yoshikazu Nakaoka, Meiko Takahashi, Eisuke Amiya, Natsuko Tamura, Toshiki Nakajima, Tomoki Origuchi, Tetsuya Horita, Mitsuru Matsukura, Yuta Kochi, Akiyoshi Ogimoto, Motohisa Yamamoto, Hiroki Takahashi, Shingo Nakayamada, Kazuyoshi Saito, Yoko Wada, Ichiei Narita, Yasushi Kawaguchi, Hisashi Yamanaka, Koichiro Ohmura, Tatsuya Atsumi, Kazuo Tanemoto, Tetsuro Miyata, Masataka Kuwana, Issei Komuro, Yasuharu Tabara, Atsuhisa Ueda, Mitsuaki Isobe, Tsuneyo Mimori, Fumihiko Matsuda. Takayasu arteritis and ulcerative colitis: high rate of co-occurrence and genetic overlap. Arthritis & rheumatology (Hoboken, N.J.). 2015.05; 67 (8): 2226-2232. ( PubMed, DOI )

Daisuke Tezuka, Masahiro Terashima, Yoko Kato, Akira Toriihara, Kensuke Hirasawa, Taro Sasaoka, Shunji Yoshikawa, Yasuhiro Maejima, Takashi Ashikaga, Jun-Ichi Suzuki, Kenzo Hirao, Mitsuaki Isobe. Clinical Characteristics of Definite or Suspected Isolated Cardiac Sarcoidosis: Application of Cardiac Magnetic Resonance Imaging and (18)F-Fluoro-2-deoxyglucose Positron-Emission Tomography/Computerized Tomography. J. Card. Fail.. 2015.04; 21 (4): 313-322. ( PubMed, DOI )

Sebastiano Sciarretta, Peiyong Zhai, Yasuhiro Maejima, Dominic P Del Re, Narayani Nagarajan, Derek Yee, Tong Liu, Mark A Magnuson, Massimo Volpe, Giacomo Frati, Hong Li, Junichi Sadoshima. mTORC2 Regulates Cardiac Response to Stress by Inhibiting MST1. Cell Rep. 2015.04; 11 (1): 125-136. ( PubMed, DOI )

Takayoshi Matsumura, Eisuke Amiya, Natsuko Tamura, Yasuhiro Maejima, Issei Komuro, Mitsuaki Isobe. A novel susceptibility locus for Takayasu arteritis in the IL12B region can be a genetic marker of disease severity. Heart Vessels. 2015.03; 31 (6): 1016-9. ( PubMed, DOI )

Yasuhiro Maejima, Yun Chen, Mitsuaki Isobe, Asa B Gustafsson, Richard N Kitsis, Junichi Sadoshima. Recent Progress in Research on Molecular Mechanisms of Autophagy in the Heart. Am. J. Physiol. Heart Circ. Physiol.. 2015.02; 308 (4): H259-H268. ( PubMed, DOI )

Yoshiyuki Ikeda, Akihiro Shirakabe, Yasuhiro Maejima, Peiyong Zhai, Sebastiano Sciarretta, Jessica Toli, Masatoshi Nomura, Katsuyoshi Mihara, Kensuke Egashira, Mitsuru Ohishi, Maha Abdellatif, Junichi Sadoshima. Endogenous Drp1 mediates mitochondrial autophagy and protects the heart against energy stress. Circ. Res.. 2015.01; 116 (2): 264-278. ( PubMed, DOI )

Yasuhiro Maejima, Junichi Sadoshima. SUMOylation: A Novel Protein Quality Control Modifier in the Heart. Circ. Res.. 2014.09; 115 (8): 686-689. ( PubMed, DOI )

Yasuhiro Maejima, Soichiro Usui, Peiyong Zhai, Masayuki Takamura, Shuichi Kaneko, Daniela Zablocki, Mitsuhiro Yokota, Mitsuaki Isobe, Junichi Sadoshima. Muscle-specific RING finger 1 negatively regulates pathological cardiac hypertrophy through downregulation of calcineurin A. Circ Heart Fail. 2014.05; 7 (3): 479-490. ( PubMed, DOI )

Dominic P Del Re, Takahisa Matsuda, Peiyong Zhai, Yasuhiro Maejima, Mohit Raja Jain, Tong Liu, Hong Li, Chiao-Po Hsu, Junichi Sadoshima. Mst1 promotes cardiac myocyte apoptosis through phosphorylation and inhibition of Bcl-xL. Mol. Cell. 2014.05; 54 (4): 639-650. ( PubMed, DOI )

Yasuhiro Maejima, Shiori Kyoi, Peiyong Zhai, Tong Liu, Hong Li, Andreas Ivessa, Sebastiano Sciarretta, Dominic P Del Re, Daniela K Zablocki, Chiao-Po Hsu, Dae-Sik Lim, Mitsuaki Isobe, Junichi Sadoshima. Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2. Nature Medicine. 2013.11; 19 (11): 1478-1488. ( PubMed, DOI )

Chikashi Terao, Hajime Yoshifuji, Akinori Kimura, Takayoshi Matsumura, Koichiro Ohmura, Meiko Takahashi, Masakazu Shimizu, Takahisa Kawaguchi, Zhiyong Chen, Taeko K Naruse, Aiko Sato-Otsubo, Yusuke Ebana, Yasuhiro Maejima, Hideyuki Kinoshita, Kosaku Murakami, Daisuke Kawabata, Yoko Wada, Ichiei Narita, Junichi Tazaki, Yasushi Kawaguchi, Hisashi Yamanaka, Kimiko Yurugi, Yasuo Miura, Taira Maekawa, Seishi Ogawa, Issei Komuro, Ryozo Nagai, Ryo Yamada, Yasuharu Tabara, Mitsuaki Isobe, Tsuneyo Mimori, Fumihiko Matsuda. Two susceptibility loci to Takayasu arteritis reveal a synergistic role of the IL12B and HLA-B regions in a Japanese population. Am. J. Hum. Genet.. 2013.08; 93 (2): 289-297. ( PubMed, DOI )

Nirmala Hariharan, Yoshiyuki Ikeda, Chull Hong, Ralph R Alcendor, Soichiro Usui, Shumin Gao, Yasuhiro Maejima, Junichi Sadoshima. Autophagy plays an essential role in mediating regression of hypertrophy during unloading of the heart. PLoS ONE. 2013; 8 (1): e51632. ( PubMed, DOI )

Yasuhiro Maejima, Jonathan Galeotti, Jeffery D Molkentin, Junichi Sadoshima, Peiyong Zhai. Constitutively active MEK1 rescues cardiac dysfunction caused by overexpressed GSK-3α during aging and hemodynamic pressure overload. Am. J. Physiol. Heart Circ. Physiol.. 2012.10; 303 (8): H979-H988. ( PubMed, DOI )

Sebastiano Sciarretta, Peiyong Zhai, Dan Shao, Yasuhiro Maejima, Jeffrey Robbins, Massimo Volpe, Gianluigi Condorelli, Junichi Sadoshima. Rheb is a critical regulator of autophagy during myocardial ischemia: pathophysiological implications in obesity and metabolic syndrome. Circulation. 2012.03; 125 (9): 1134-1146. ( PubMed, DOI )

Soichiro Usui, Yasuhiro Maejima, Jayashree Pain, Chull Hong, Jaeyeaon Cho, Ji Yeon Park, Daniela Zablocki, Bin Tian, David J Glass, Junichi Sadoshima. Endogenous muscle atrophy F-box mediates pressure overload-induced cardiac hypertrophy through regulation of nuclear factor-kappaB. Circ. Res.. 2011.07; 109 (2): 161-171. ( PubMed, DOI )

Yasuhiro Maejima, Hiroyuki Okada, Go Haraguchi, Yasuyuki Onai, Hisanori Kosuge, Jun-Ichi Suzuki, Mitsuaki Isobe. Telmisartan, a unique ARB, improves left ventricular remodeling of infarcted heart by activating PPAR gamma. Lab. Invest.. 2011.06; 91 (6): 932-944. ( PubMed, DOI )

Yasuhiro Maejima, Junya Kuroda, Shouji Matsushima, Tetsuro Ago, Junichi Sadoshima. Regulation of myocardial growth and death by NADPH oxidase. J. Mol. Cell. Cardiol.. 2011.03; 50 (3): 408-416. ( PubMed, DOI )

Jaeyeaon Cho, Peiyong Zhai, Yasuhiro Maejima, Junichi Sadoshima. Myocardial injection with GSK-3β-overexpressing bone marrow-derived mesenchymal stem cells attenuates cardiac dysfunction after myocardial infarction. Circ. Res.. 2011.02; 108 (4): 478-489. ( PubMed, DOI )

Yasuhiro Maejima, Kiyoshi Nobori, Yuichi Ono, Susumu Adachi, Jun-Ichi Suzuki, Kenzo Hirao, Mitsuaki Isobe, Hiroshi Ito, . Synergistic effect of combined HMG-CoA reductase inhibitor and angiotensin-II receptor blocker therapy in patients with chronic heart failure: the HF-COSTAR trial. Circ. J.. 2011; 75 (3): 589-595. ( PubMed, DOI )

Nirmala Hariharan, Yasuhiro Maejima, Jun Nakae, Jihye Paik, Ronald A Depinho, Junichi Sadoshima. Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes. Circ. Res.. 2010.12; 107 (12): 1470-1482. ( PubMed, DOI )

Chiao-Po Hsu, Peiyong Zhai, Takanobu Yamamoto, Yasuhiro Maejima, Shouji Matsushima, Nirmala Hariharan, Dan Shao, Hiromitsu Takagi, Shinichi Oka, Junichi Sadoshima. Silent information regulator 1 protects the heart from ischemia/reperfusion. Circulation. 2010.11; 122 (21): 2170-2182. ( PubMed, DOI )

Jun-ichi Suzuki, Masahito Ogawa, Noriko Tamura, Yasuhiro Maejima, Kiyoshi Takayama, Koji Maemura, Kazuki Honda, Yasunobu Hirata, Ryozo Nagai, Mitsuaki Isobe. A critical role of sympathetic nerve regulation for the treatment of impaired daily rhythm in hypertensive Dahl rats. Hypertens. Res.. 2010.10; 33 (10): 1060-1065. ( PubMed, DOI )

Hiromitsu Takagi, Chiao-Po Hsu, Katsuya Kajimoto, Dan Shao, Yanfei Yang, Yasuhiro Maejima, Peiyong Zhai, Ghassan Yehia, Chikaomi Yamada, Daniela Zablocki, Junichi Sadoshima. Activation of PKN mediates survival of cardiac myocytes in the heart during ischemia/reperfusion. Circ. Res.. 2010.09; 107 (5): 642-649. ( PubMed, DOI )

Hisanori Kosuge, Takashi Ishihara, Go Haraguchi, Yasuhiro Maejima, Hiroyuki Okada, Hitoshi Saiki, Jun-ichi Suzuki, Mitsuaki Isobe. Treatment with telmisartan attenuates graft arteriosclerosis in murine cardiac allografts. J. Heart Lung Transplant.. 2010.05; 29 (5): 562-567. ( PubMed, DOI )

Kazuya Isobe, Keiji Kuba, Yasuhiro Maejima, Jun-Ichi Suzuki, Shunichiro Kubota, Mitsuaki Isobe. Inhibition of endostatin/collagen XVIII deteriorates left ventricular remodeling and heart failure in rat myocardial infarction model. Circ. J.. 2010.01; 74 (1): 109-119. ( PubMed, DOI )

Ricardo J Gelpi, Shumin Gao, Peiyong Zhai, Lin Yan, Chull Hong, Lauren M A Danridge, Hui Ge, Yasahiro Maejima, Martin Donato, Mitsuhiro Yokota, Jeffery D Molkentin, Dorothy E Vatner, Stephen F Vatner, Junichi Sadoshima. Genetic inhibition of calcineurin induces diastolic dysfunction in mice with chronic pressure overload. Am. J. Physiol. Heart Circ. Physiol.. 2009.11; 297 (5): H1814-H1819. ( PubMed, DOI )

Masanori Konishi, Yasuhiro Maejima, Hiroshi Inagaki, Go Haraguchi, Hitoshi Hachiya, Junichi Suzuki, Kenzo Hirao, Mitsuaki Isobe. Clinical characteristics of acute decompensated heart failure with rapid onset of symptoms. J. Card. Fail.. 2009.05; 15 (4): 300-304. ( PubMed, DOI )

Takaaki Haga, Jun-Ichi Suzuki, Hisanori Kosuge, Masahito Ogawa, Hitoshi Saiki, Go Haraguchi, Yasuhiro Maejima, Mitsuaki Isobe, Toshimitsu Uede. Attenuation of experimental autoimmune myocarditis by blocking T cell activation through 4-1BB pathway. J. Mol. Cell. Cardiol.. 2009.05; 46 (5): 719-727. ( PubMed, DOI )

Takahisa Matsuda, Peiyong Zhai, Yasuhiro Maejima, Chull Hong, Shumin Gao, Bin Tian, Kazumichi Goto, Hiromitsu Takagi, Mimi Tamamori-Adachi, Shigetaka Kitajima, Junichi Sadoshima. Distinct roles of GSK-3alpha and GSK-3beta phosphorylation in the heart under pressure overload. Proc. Natl. Acad. Sci. U.S.A.. 2008.12; 105 (52): 20900-20905. ( PubMed, DOI )

Mimi Tamamori-Adachi, Hiromitsu Takagi, Kimio Hashimoto, Kazumichi Goto, Toshinori Hidaka, Uichi Koshimizu, Kazuhiko Yamada, Ikuko Goto, Yasuhiro Maejima, Mitsuaki Isobe, Keiichi I Nakayama, Norio Inomata, Shigetaka Kitajima. Cardiomyocyte proliferation and protection against post-myocardial infarction heart failure by cyclin D1 and Skp2 ubiquitin ligase. Cardiovasc. Res.. 2008.11; 80 (2): 181-190. ( PubMed, DOI )

Go Haraguchi, Hisanori Kosuge, Yasuhiro Maejima, Jun-Ichi Suzuki, Takasuke Imai, Masayuki Yoshida, Mitsuaki Isobe. Pioglitazone reduces systematic inflammation and improves mortality in apolipoprotein E knockout mice with sepsis. Intensive Care Med. 2008.07; 34 (7): 1304-1312. ( PubMed, DOI )

Akiyo Karube, Jun-ichi Suzuki, Go Haraguchi, Yasuhiro Maejima, Hitoshi Saiki, Hisanori Kosuge, Mitsuaki Isobe, Toshimitsu Uede. Suppression of neointimal hyperplasia after vascular injury by blocking 4-1BB/4-1BB ligand pathway. J. Med. Dent. Sci.. 2008.06; 55 (2): 207-213. ( PubMed )

Yasuhiro Maejima, Susumu Adachi, Hiroshi Ito, Kenzo Hirao, Mitsuaki Isobe. Induction of premature senescence in cardiomyocytes by doxorubicin as a novel mechanism of myocardial damage. Aging Cell. 2008.03; 7 (2): 125-136. ( PubMed, DOI )

Hitoshi Saiki, Jun-Ichi Suzuki, Hisanori Kosuge, Go Haraguchi, Takashi Ishihara, Takaaki Haga, Yasuhiro Maejima, Mitsuaki Isobe, Toshimitsu Uede. Blockade of the 4-1BB pathway attenuates graft arterial disease in cardiac allografts. Int Heart J. 2008.01; 49 (1): 105-118. ( PubMed, DOI )

Hiroyuki Okada, Jun-ichi Suzuki, Hideki Futamatsu, Yasuhiro Maejima, Kenzo Hirao, Mitsuaki Isobe. Attenuation of autoimmune myocarditis in rats by mesenchymal stem cell transplantation through enhanced expression of hepatocyte growth factor. Int Heart J. 2007.09; 48 (5): 649-661. ( PubMed, DOI )

Jun-ichi Suzuki, Noritaka Koga, Hisanori Kosuge, Masahito Ogawa, Go Haraguchi, Yasuhiro Maejima, Hitoshi Saiki, Mitsuaki Isobe. Pitavastatin suppresses acute and chronic rejection in murine cardiac allografts. Transplantation. 2007.04; 83 (8): 1093-1097. ( PubMed, DOI )

Jun-ichi Suzuki, Masahito Ogawa, Yasuhiro Maejima, Kazuya Isobe, Hiroyuki Tanaka, Yuko M Sagesaka, Mitsuaki Isobe. Tea catechins attenuate chronic ventricular remodeling after myocardial ischemia in rats. J. Mol. Cell. Cardiol.. 2007.02; 42 (2): 432-440. ( PubMed, DOI )

Yasuyuki Onai, Jun-Ichi Suzuki, Yasuhiro Maejima, Go Haraguchi, Susumu Muto, Akiko Itai, Mitsuaki Isobe. Inhibition of NF-{kappa}B improves left ventricular remodeling and cardiac dysfunction after myocardial infarction. Am. J. Physiol. Heart Circ. Physiol.. 2007.01; 292 (1): H530-H538. ( PubMed, DOI )

Hisanori Kosuge, Jun-ichi Suzuki, Go Haraguchi, Noritaka Koga, Yasuhiro Maejima, Manabu Inobe, Mitsuaki Isobe, Toshimitsu Uede. Critical role of inducible costimulator signaling in the development of arteriosclerosis. Arterioscler. Thromb. Vasc. Biol.. 2006.12; 26 (12): 2660-2665. ( PubMed, DOI )

Kino Morikawa-Futamatsu, Susumu Adachi, Yasuhiro Maejima, Mimi Tamamori-Adachi, Jun-ichi Suzuki, Shigetaka Kitajima, Hiroshi Ito, Mitsuaki Isobe. HMG-CoA reductase inhibitor fluvastatin prevents angiotensin II-induced cardiac hypertrophy via Rho kinase and inhibition of cyclin D1. Life Sci.. 2006.08; 79 (14): 1380-1390. ( PubMed, DOI )

Hisanori Kosuge, Go Haraguchi, Noritaka Koga, Yasuhiro Maejima, Jun-ichi Suzuki, Mitsuaki Isobe. Pioglitazone prevents acute and chronic cardiac allograft rejection. Circulation. 2006.06; 113 (22): 2613-2622. ( PubMed, DOI )

Hideki Futamatsu, Jun-ichi Suzuki, Noritaka Koga, Susumu Adachi, Hisanori Kosuge, Yasuhiro Maejima, Takaaki Haga, Kenzo Hirao, Richard Horuk, Mitsuaki Isobe. A CCR1 antagonist prevents the development of experimental autoimmune myocarditis in association with T cell inactivation. J. Mol. Cell. Cardiol.. 2006.06; 40 (6): 853-861. ( PubMed, DOI )

Yasuhiro Maejima, Takanori Yasu, Hiroto Ueba, Nobuhiko Kobayashi, Shigemasa Hashimoto, Norifumi Kubo, Akihiro Kakehashi, Mitsuaki Isobe, Masanobu Kawakami, Muneyasu Saito. Exercise after heparin administration: new therapeutic program for patients with-option arteriosclerosis oblitrans. Circ. J.. 2005.09; 69 (9): 1099-1104. ( PubMed )

Hideki Futamatsu, Jun-ichi Suzuki, Shinya Mizuno, Noritaka Koga, Susumu Adachi, Hisanori Kosuge, Yasuhiro Maejima, Kenzo Hirao, Toshikazu Nakamura, Mitsuaki Isobe. Hepatocyte growth factor ameliorates the progression of experimental autoimmune myocarditis: a potential role for induction of T helper 2 cytokines. Circ. Res.. 2005.04; 96 (8): 823-830. ( PubMed, DOI )

Yasuhiro Maejima, Susumu Adachi, Kino Morikawa, Hiroshi Ito, Mitsuaki Isobe. Nitric oxide inhibits myocardial apoptosis by preventing caspase-3 activity via S-nitrosylation. J. Mol. Cell. Cardiol.. 2005.01; 38 (1): 163-174. ( PubMed, DOI )

Noritaka Koga, Jun-ichi Suzuki, Hisanori Kosuge, Go Haraguchi, Yasuyuki Onai, Hideki Futamatsu, Yasuhiro Maejima, Ryo Gotoh, Hitoshi Saiki, Fumihiko Tsushima, Miyuki Azuma, Mitsuaki Isobe. Blockade of the interaction between PD-1 and PD-L1 accelerates graft arterial disease in cardiac allografts. Arterioscler. Thromb. Vasc. Biol.. 2004.11; 24 (11): 2057-2062. ( PubMed, DOI )

Yasuhiro Maejima, Takanori Yasu, Norifumi Kubo, Koji Kawahito, Nobuhiro Omura, Takaaki Katsuki, Yoshiaki Tsukamoto, Yoshitaka Sugawara, Shigemasa Hashimoto, Yoshio Tsuruya, Taishi Hirahara, Yosuke Takagi, Nobuhiko Kobayashi, Hiroshi Funayama, Nahoko Ikeda, Takeshi Ishida, Mikihisa Fujii, Takashi Ino, Muneyasu Saito. Long-term prognosis of fulminant myocarditis rescued by percutaneous cardiopulmonary support device. Circ. J.. 2004.09; 68 (9): 829-833. ( PubMed )

Yasuyuki Onai, Jun-Ichi Suzuki, Tsunekazu Kakuta, Yasuhiro Maejima, Go Haraguchi, Hiroshi Fukasawa, Susumu Muto, Akiko Itai, Mitsuaki Isobe. Inhibition of IkappaB phosphorylation in cardiomyocytes attenuates myocardial ischemia/reperfusion injury. Cardiovasc. Res.. 2004.07; 63 (1): 51-59. ( PubMed, DOI )

Yasuhiro Maejima, Susumu Adachi, Hiroshi Ito, Kiyoshi Nobori, Mimi Tamamori-Adachi, Mitsuaki Isobe. Nitric oxide inhibits ischemia/reperfusion-induced myocardial apoptosis by modulating cyclin A-associated kinase activity. Cardiovasc. Res.. 2003.08; 59 (2): 308-320. ( PubMed, DOI )

Yasuhiro Maejima, Hiroto Ueba, Masatoshi Kuroki, Takanori Yasu, Shigemasa Hashimoto, Aoi Nabata, Nobuhiko Kobayashi, Nahoko Ikeda, Muneyasu Saito, Masanobu Kawakami. Src family kinases and nitric oxide production are required for hepatocyte growth factor-stimulated endothelial cell growth. Atherosclerosis. 2003.03; 167 (1): 89-95. ( PubMed )

Yasuhiro Maejima, Takanori Yasu, Naoki Fujiwara, Takeshi Ishida, Yasuyuki Kobayashi, Masatoshi Kuroki, Norifumi Kubo, Mikihisa Fujii, Muneyasu Saito. Vasospastic total occlusion at the left main tract in a single coronary artery. Jpn. Circ. J.. 2001.12; 65 (12): 1091-1092. ( PubMed )

S Ikeda, Y Takabayashi, Y Maejima, N Tachibana, T Ehara, A Nezu, Y Hoshii. Nodular lung disease with five year survival and unilateral pleural effusion in AL amyloidosis. Amyloid. 1999.12; 6 (4): 292-296. ( PubMed, DOI )

K Y Wang, M B Kimmey, D A Nyberg, L A Mack, R C Haggitt, W P Shuman, D W Franklin, F E Silverstein. Colorectal neoplasms: accuracy of US in demonstrating the depth of invasion. Radiology. 1987.12; 165 (3): 827-829. ( PubMed, DOI )

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前嶋 康浩. 【心不全のすべて-増え続ける心不全患者にどう対峙するか】心不全の診断と治療　β遮断薬とivabradineの使い方 内科. 2021.07; 128 (1): 25-29. ( 医中誌 )

前嶋康浩. がん治療関連心機能障害（CTRCD） 心臓. 2020.12; 52 (12): 12-20. ( 医中誌 )

前嶋 康浩. 【腫瘍循環器学-新時代を迎えた腫瘍循環器学】がん治療関連心機能障害(CTRCD) 心臓. 2020.12; 52 (12): 1324-1331. ( 医中誌 )

前嶋 康浩. 小胞体選択的オートファジーの分子機構および疾患の関わり BIO Clinica. 2020.11; 35 (12): 1149-1153. ( 医中誌 )

前嶋 康浩. 【血管炎症候群を理解する】診る　大型血管炎の画像診断には何を使うのが良いか? Heart View. 2020.08; 24 (8): 708-713. ( 医中誌 )

前嶋 康浩. オートファジーの心臓における役割 循環器内科. 2020.05; 87 (5): 672-678. ( 医中誌 )

田村 夏子, 前嶋 康浩. 【リウマチ性疾患の病因・病態研究の進歩】高安動脈炎とMLX遺伝子変異 リウマチ科. 2020.02; 63 (2): 196-201. ( 医中誌 )

前嶋 康浩. 【循環器症候群(第3版)-その他の循環器疾患を含めて-】大動脈疾患　高安動脈炎 日本臨床. 2019.10; 別冊 (循環器症候群II): 371-375. ( 医中誌 )

前嶋 康浩. 【指定難病ペディア2019】個別の指定難病　免疫系　高安動脈炎[指定難病40] 日本医師会雑誌. 2019.06; 148 (特別1): S160-S161. ( 医中誌 )

永野 勝稔, 小山 祥美, 北村 優佳, 山本 雄彬, 佐藤 明日香, 町田 友美, 萩原 三千男, 東田 修二, 山本 貴信, 前嶋 康浩, 平尾 見三. Fabry病を疑う契機となった尿沈渣中のマルベリー細胞の意義 臨床病理. 2019.02; 67 (2): 112-116. ( 医中誌 )

前嶋 康浩. 【心不全の分子機序】タンパククオリティーコントロール：オートファジー 【心不全(第2版)上-最新の基礎・臨床研究の進歩-】心不全の基礎研究　. 2018.12; 76 (増刊9 心不全(上)): 216-223. ( 医中誌 )

前嶋 康浩. 【心不全(第2版)上-最新の基礎・臨床研究の進歩-】疫学　欧米における心不全の疫学的研究の概要 日本臨床. 2018.12; 76 (増刊9 心不全(上)): 51-56. ( 医中誌 )

前嶋 康浩. 【血管炎(第2版)-基礎と臨床のクロストーク-】大型血管炎　高安動脈炎　病態 日本臨床. 2018.07; 76 (増刊6 血管炎(第2版)): 102-106. ( 医中誌 )

前嶋康浩. オートファジーの制御異常による心不全発症機構の解明 日本薬理学雑誌. 2018.03; 151 (3): 100-105. ( PubMed, DOI )

前嶋 康浩. 【革新的心不全治療戦略創出を指向した心機能制御機構の新たな展開】オートファジーの制御異常による心不全発症機構の解明 日本薬理学雑誌. 2018.03; 151 (3): 100-105. ( 医中誌 )

磯部 光章, 市川 肇, 植田 初江, 小野 稔, 北風 政史, 小林 順二郎, 坂田 泰史, 佐野 俊二, 澤 芳樹, 中谷 武嗣, 布田 伸一, 福嶌 教偉, 福田 恵一, 町野 朔, 丸山 英二, 安河内 聰, 山崎 健二, 横田 裕行, 芦刈 淳太郎, 遠藤 美代子, 加藤 文代, 絹川 弘一郎, 絹川 真太郎, 久保田 香, 小垣 滋豊, 齋木 佳克, 篠岡 太郎, 西垣 和彦, 西村 勝治, 肥後 太基, 平田 康隆, 前嶋 康浩, 簗瀬 正伸, 今泉 勉, 小柳 仁, 中西 敏雄, 松居 喜郎, 百村 伸一, 山本 一博, 日本循環器学会, 日本心臓病学会, 日本心臓血管外科学会, 日本心不全学会, 日本小児循環器学会, 日本移植学会, 日本救急医学会, 日本胸部外科学会, 厚生労働省心筋症研究班. 心臓移植に関する提言【2016年版】 日本心臓血管外科学会雑誌. 2018.01; 47 (1): (1)-(61). ( 医中誌 )

前嶋康浩. 血管炎の臨床UPDATE「高安動脈炎」 医学のあゆみ. 2017.11; 263 (6): 485-489.

前嶋 康浩. 【血管炎の臨床UPDATE】高安動脈炎 医学のあゆみ. 2017.11; 263 (6): 485-489. ( 医中誌 )

前嶋康浩. Dipeptidyl peptidase-4による適応現象を標的とした心血管疾患の新たな標的についての検討 –自己免疫性心筋炎に対するアプローチを中心に– 適応医学. 2017.07; 20 (2): 21-26. ( 医中誌 )

前嶋康浩、磯部光章. 高安動脈炎【Ⅶ. 血管炎　大型血管炎】 日本臨床75巻増刊号5 動脈・静脈の疾患(下) (通巻第1124号). 2017.07; 75 (増刊5): 946-951.

前嶋 康浩, 磯部 光章. Dipeptidyl peptidase-4による適応現象を標的とした心血管疾患の新たな標的についての検討　自己免疫性心筋炎に対するアプローチを中心に 適応医学. 2017.07; 20 (2): 21-26. ( 医中誌 )

前嶋 康浩, 磯部 光章. 【動脈・静脈の疾患(下)-最新の診断・治療動向-】血管炎　大型血管炎　高安動脈炎 日本臨床. 2017.07; 75 (増刊5 動脈・静脈の疾患(下)): 946-951. ( 医中誌 )

前嶋 康浩. 【脳血管障害　診療のエッセンス】脳血管障害の危険因子　心血管疾患　心房細動以外の心血管疾患 日本医師会雑誌. 2017.06; 146 (特別1): S100-S101. ( 医中誌 )

前嶋康浩. 新薬紹介：高LDLコレステロール血症治療薬　エボロクマブ（遺伝子組み換え） 日本医師会雑誌. 2017.04;

前嶋康浩. 筋ジストロフィーに伴う心筋症　 循環器内科. 2017.02; 79 (2): 300-310.

前嶋康浩. 心臓リモデリング・心不全　将来へのチャレンジ　心筋リモデリングとオートファジー 心臓. 2017.02; 49 (2): 167-175. ( 医中誌 )

前嶋 康浩. 免疫異常を基盤とした拡張型心筋症の発症におけるMst1キナーゼの役割の解明 医科学応用研究財団研究報告. 2017.02; 34 225-227. ( 医中誌 )

前嶋 康浩. 【二次性心筋症の臨床】筋ジストロフィーに伴う心筋症 循環器内科. 2017.01; 81 (1): 36-43. ( 医中誌 )

磯部光章、前嶋康浩. 【遺伝性心筋疾患の現状と展望を識る】企画にあたって Heart View. 2016.02; 20 (2): 6-7.

前嶋康浩. 【話題】心不全とオートファジー　 循環器内科. 2015.11; 78 (5): 512-519.

前嶋康浩. 【希少な心血管疾患を見直す】ミトコンドリア心筋症　 循環器内科. 2015.10; 78 (4): 319-324.

前嶋康浩、磯部光章. 【心不全の最前線】治す - 新しい心不全治療薬の展望 Heart View. 2014.01; 18 (1): 72-79. ( 医中誌 )

前嶋康浩、磯部光章、佐渡島純一. 【循環器のエイジングバイオロジー】心筋細胞の老化 血管医学. 2010.05; 11 (2): 125-133. ( 医中誌 )

前嶋康浩、磯部光章. 超音波で診る心疾患-大動脈解離 綜合臨床. 2007.10; 56 (10): 2936-2942. ( 医中誌 )

【心不全　最新の基礎・臨床研究の進歩】疫学 - 欧米における心不全の疫学的研究の概要 日本臨床(0047-1852)巻 心不全(上) Page-(2007.04). 2007.04; 65 (増刊4): 55-60. ( 医中誌 )

Maejima Y, Isobe M. [Epidemiology of heart failure in western countries]. Nihon rinsho. Japanese journal of clinical medicine. 2007.04; 65 Suppl 4 55-60. ( PubMed )

前嶋康浩、畑明宏、磯部光章. 超音波で診る心疾患-大動脈弁閉鎖不全 綜合臨牀. 2006.05; 55 (5): 1559-1567. ( 医中誌 )

前嶋康浩. 細胞の早期老化現象と心血管疾患 Pharma Medica. 2006.05; 24 (5): 115-117. ( 医中誌 )

前嶋康浩、磯部光章. 【慢性心不全を最近の知見から整理する　病態生理から治療まで】心不全の疫学-本邦と欧米を比較して Medicina. 2004.11; 41 (11): 1781-1783. ( 医中誌 )

前嶋康浩、磯部光章. 胸痛,めまい,労作時息切れを訴える67歳,女性 臨床医. 2003.08; 29 (8): 1625-1627. ( 医中誌 )

前嶋康浩、伊藤宏. 【心不全と不整脈】　頻脈誘発性心筋症　心不全治療,不整脈治療 循環器科. 2002.07; 52 (1): 63-68. ( 医中誌 )

前嶋康浩、安隆則、磯部光章. 【心不全の診かた,治しかた】　基礎疾患別にみた心不全　心筋症 臨床医. 2002.04; 28 (4): 442-446. ( 医中誌 )

前嶋康浩. 『日本医師会雑誌』 第148巻・特別号（2）（生涯教育シリーズ　97）動脈硬化診療のすべて. 日本医師会/南江堂, 2019.06 (ISBN : 978-4-524-22755-6)

前嶋康浩. 循環器臨床のリアルワールド[2] － 循環器専門医志望者編 － . MEDSi, 2017.09 左冠動脈主幹部の急性心筋梗塞による心原性ショックをきたした1例／心筋生検により心アミロイドーシスと診断された1例 (ISBN : 978-4-89592-896-0)

前嶋康浩. 循環器臨床のリアルワールド[1] － 研修医・内科医・コメディカル編 － . MEDSi, 2017.09 病態を見据えた身体所見の取り方／心原性ショックで搬送されてきた1例　 (ISBN : 978-4-89592-895-3)

前嶋康浩、磯部光章. 1336専門家による私の治療 2017-18年度版. 日本医事新報社, 2017.07 拡張型心筋症 (ISBN : 978-4-7849-4650-1)

前嶋康浩. 『日本医師会雑誌』 第146巻・特別号（１）（生涯教育シリーズ　92）脳血管障害診療のエッセンス. 日本医師会, 2017.06 心房細動以外の心血管疾患

前嶋康浩. Integrated Cardiac Imaging 画像で病態に迫る, 治療効果を判定する. メジカルビュー社, 2016.10 心筋炎に迫る–慢性心筋炎 (ISBN : 978-4-7583-1433-6)

前嶋康浩. 医学部・大学病院の教育・研究活性化及び地域・へき地医療支援人材の確保【事業報告書】. 東京医科歯科大学医学部附属病院, 2013.03 派遣病院の実績 - 蓮田病院

前嶋康浩. 六訂版 家庭医学大百科. 法研, 2010.10 心筋症（特発性、二次性）、心サルコイドーシス、肺性心、心臓神経症 (ISBN : 978-4-87954-820-7)

前嶋康浩. 改訂第3版　薬の処方ハンドブック. 羊土社, 2008.04 大動脈炎症候群 (ISBN : 978-4-7581-0644-3)

前嶋康浩. 新・心臓病診療プラクティス10　心筋症を識る・診る・治す. 文光堂, 2007.09 神経筋疾患に伴う心筋症 (ISBN : 978-4-8306-1689-1)

Yasuhiro Maejima. Chemical Proteomics-Guided Identification of a Novel Target of Empagliflozin, a SGLT2 inhibitor. Seminar at RNJMS-CBMM 2019.11.19 Newark, NJ, USA

Yasuhiro Maejima. Empagliflozin, a SGLT2 Inhibitor, Directly Protects Cardiomyocytes by off-target Effect-mediated Promotion of Mitophagy. American Heart Association Scientific Sessions 2019 2019.11.18 Philadelphia, PA, USA

Yasuhiro Maejima. Factor Xa Exacerbates Atherosclerosis by Promoting Inflammasome Formation through PAR2-mediated Autophagy Suppression. The 3rd JCS Council Forum on Basic Cardiovascular Research 2019.09.06 東京都中央区

Yasuhiro Maejima. Single Nucleotide Polymorphism of MLX Gene is Associated with the Pathogenesis of Takayasu Arteritis. 第83回日本循環器学会学術集会 2019.03.29 神奈川県横浜市

Yasuhiro Maejima. The single nucleotide polymorphism of MLX gene is involved in the development of Takayasu Arteritis. The 2nd JCS Council Forum on Basic Cardiovascular Research 2018.09.23 Nara, Japan

Yasuhiro Maejima, Yuka Shiheido-Watanabe, Natsuko Tamura, Yusuke Ito, Kenzo Hirao, Mitsuaki Isobe. Critical role for dipeptidyl peptidase-4 activity in the pathogenesis of experimental autoimmune myocarditis. Heart Failure Congress 2018 2018.05.29 Viena, Austria

Yasuhiro Maejima, Yusuke Ito, Natsuko Tamura, Masanori Konishi, Mitsuaki Isobe. Blood coagulation factor Xa promotes the progression of atherosclerosis by enhancing inflammasome formation as a consequence of PAR2-mediated autophagy inhibition. ESC Congress 2017 2017.08.26 Barcerona, Spain

Yasuhiro Maejima, Yusuke Ito, Natsuko Tamura, Masanori Konishi, Mitsuaki Isobe. Factor Xa Deteriorates Atherosclerosis by Facilitating Inflammasome Formation via PAR-2-mediated Autophagy Suppression. AHA Basic Cardiovascular Sciences 2017 2017.07.10 Portland, Oregon, USA

Maejima Yasuhiro. TXNIP accumulation caused by single nucleotide polymorphism of MLX gene enhances inflammasome formation, thereby promoting the development of Takayasu Arteritis. The 18th International Vasculitis and ANCA Workshop  2017.03.27 Tokyo, Japan

Yasuhiro Maejima, Narayani Nagarajan, Peiyong Zhai, Mitsuaki Isobe, Junichi Sadoshima. GSK-3β inhibits cardiac hypertrophy by phosphorylating FoxO1. American Heart Association Scientific Sessions 2016 2016.11.15 New Orleans, LA, USA

Yasuhiro Maejima, Yusuke Ito, Natsuko Tamura, Mitsuaki Isobe. Critical role for dipeptidyl peptidase-4 activity the pathogenesis of experimental autoimmune myocarditis. Basic Cardiovascular Sciences 2016 Scientific Sessions of American Heart Association 2016.07.20 Phoenix, Arizona, U.S.A.

Yasuhiro Maejima, Yusuke Ito, Natsuko Tamura, Ryo Watanabe, Mitsuaki Isobe. Suppression of dipeptidyl peptidase-4 activity attenuates cardiac dysfunction during autoimmune myocarditis by suppressing cathepsin-G activity. 第80回日本循環器学会学術集会 2016.03.18 宮城県仙台市

Yasuhiro Maejima, Yusuke Ito, Natsuko Tamura, Ryo Watanabe, Mitsuaki Isobe. Dipeptidyl peptidase-4 deteriorates cardiac function during autoimmune myocarditis by facilitating cathepsin-G activity. American Heart Association Scientific Sessions 2015 2015.11.09 Orlando, FL, USA

Yasuhiro Maejima, Natsuko Tamura, Mitsuaki Isobe. Single Nucleotide Polymorphism of MLX Gene Plays a Crucial Role in the Pathogenesis of Takayasu Arteritis Through Facilitating Inflammasome Formation of the Aorta. Basic Cardiovascular Sciences 2015 Scientific Sessions of American Heart Association 2015.07 New Orleans, Louisiana, U.S.A.

Yasuhiro Maejima, Natsuko Tamura, Mitsuaki Isobe. Mutation of MLX gene plays an important role in the pathogenesis of Takayasu Arteritis by promoting inflammasome formation. American Heart Association Scientific Sessions 2014 2014.11.18 Chicago, IL, USA

Yasuhiro Maejima, Narayani Nagarajan, Peiyong Zhai, Mitsuaki Isobe, Junichi Sadoshima. Mst1 plays a protective role in response to ischemia in the heart by promoting C/EBP-β activation. American Heart Association Scientific Sessions 2014 2014.11.17 Chicago, IL, USA

Maejima Y, Adachi S, Isobe M. Synergistic Salutary Effects of HMG-CoA Reductase Inhibitor and Angiotensin II Receptor Blocker on Load-induced Heart Failure. Basic Cardiovascular Sciences 2014 Scientific Sessions of American Heart Association 2014.07 Las Vegas, NV, U.S.A.

Maejima Y, Zhai P, Isobe M, Sadoshima J. Mst1 mediates a cell-protective mechanism in the heart through phosphorylation of FoxO1 and C/EBP-β. American Heart Association Scientific Sessions 2013 2013.11 Dallas, TX, U.S.A.

Yasuhiro Maejima, Mitsuaki Isobe, Junichi Sadoshima. Mst1 inhibits autophagy by promoting Beclin1-Bcl-2 interaction, thereby compromising protein quality control in failing hearts. 第77回日本循環器学会学術集会 2013.03 神奈川県横浜市

Yasuhiro Maejima, Peiyong Zhai, Tong Liu, Hong Li, Junichi Sadoshima. Mst1-mediated phosphorylation of FoxO1 and C/EBP-β stimulates cell protective mechanisms in cardiomyocytes. American Heart Association Scientific Sessions 2012 2012.11 Los Angeles, CA, U.S.A.

Maejima Y, Kyoi S, Zhai P, Liu T, Li H, Sadoshima J. Mst1-Mediated Phosphorylation of Beclin1 in its BH3 Domain Promotes Beclin1-Bcl-2 Interaction, Thereby Negatively Regulating Autophagy in the Heart. American Heart Association Scientific Sessions 2011 2011.11 Orlando, FL, U.S.A.

Maejima Y, Zhai P, Kundu M, Sadoshima J. Mammalian UNC-51-like Kinase (ULK)-1 Plays a Crucial Role in Mediating Autophagy Under Stress Conditions in the Heart. American Heart Association Scientific Sessions 2011 2011.11 Orlando, FL, U.S.A.

Maejima Y, Zhai P, Sadoshima J. GSK-3β Prevents Cardiac Dysfunction through Modulation of FoxO1 Activity Under Pressure Overload. American Heart Association Scientific Sessions 2011 2011.11 Orlando, FL, U.S.A.

Maejima Y, Kyoi S, Zhai P, Sadoshima J. Mst1 Physically Interacts with and Phosphorylates Beclin1, Thereby Negatively Regulating Autophagy in the Heart. American Heart Association Scientific Sessions 2011 2011.11 Orlando, FL, U.S.A.

Maejima Y, Zhai P, Sadoshima J. Mst1 Stimulates Cell Protective Mechanisms of FoxO1 Through Phosphorylation in Cardiomyocytes. American Heart Association Scientific Sessions 2010 2010.11 Chicago, IL, U.S.A.

Maejima Y, Zhai P, Sadoshima J. GSK3β Inhibits Cardiac Hypertrophy through FoxO1, but Protects the Heart from Dysfunction Independently of FoxO1 under Pressure Overload. American Heart Association Scientific Sessions 2010 2010.11 Chicago, IL, U.S.A.

Maejima Y, Zhai P, Yamamoto T, Matsuda T, Sadoshima J. E2F2/4 Regulated by Serine 21 Phosphorylation of GSK-3α Plays Compensatory Roles Under Pressure Overload. American Heart Association Scientific Sessions 2010 2010.11 Chicago, IL, U.S.A.

Maejima Y, Sadoshima J. Mst1 Physically Interacts with and Phosphorylates FoxO1, thereby Stimulating Cell Protective Mechanisms of FoxO1 in the Heart. American Heart Association Scientific Sessions 2009 2009.11 Orlando, FL, U.S.A.

Maejima Y, Zhai P, Sadoshima J. GSK3β Negatively Regulates Cardiac Hypertrophy through Activation of FoxO . American Heart Association Scientific Sessions 2009 2009.11 Orlando, FL, U.S.A.

Maejima Y, Tamamori-Adachi M, Yamada K, Adachi S, Kitajima S, Isobe M. Important Role of FGF Signaling and p27kip1 in Adult Cardiomyocyte Cell Cycle Regulation . American Heart Association Scientific Sessions 2008 2008.11 New Orleans, LA, U.S.A.

Maejima Y, Adachi S, Isobe M. Oxidative Stress Induce Myocardial Atrophy by Modulating Nuclear Translocation of FoxO1 Transcription Factor. 第72回日本循環器学会学術集会 2008.03 福岡県福岡市

Maejima Y, Adachi S, Ito H, Isobe M. Induction of premature senescence in cardiomyocytes by oxidative stress as a novel mechanism of myocardial dysfunction. American Heart Association Scientific Sessions 2006 2006.11 Chicago, IL, U.S.A.

Maejima Y, Adachi S, Ito H, Isobe M. Premature senescence can be induced by oxidative stress via PML-p53 acetylation pathway in cardiomyocytes. 第70回日本循環器学会学術集会 2006.03 愛知県名古屋市

Maejima Y, Adachi S, Morikawa K, Ito H, Isobe M. Senescence-like alterations by oxidative stress is novel mechanism of cardiomyocyte dysfunction. 第69回日本循環器学会学術集会 2005.03

Maejima Y, Adachi S, Morikawa K, Nobori K, Tamamori-Adachi M, Isobe M, Ito H. Nitric oxide inhibits hypoxia/reoxygenation-induced myocardial apoptosis by modulating cyclin A-associated kinase activity. American Heart Association Scientific Sessions 2003 2003.11 Orlando, FL, U.S.A.

Maejima Y, Adachi S, Nobori K, Morikawa K, Tamamori-Adachi M, Ito H, Isobe M. Endogenous nitric oxide inhibits hypoxia/reoxygenation-induced myocardial apoptosis with the modulation of cyclin A-associated kinase activity. 第67回日本循環器学会学術集会 2003.03 福岡県福岡市

Maejima Y, Yasu T, Iwasawa T, Ueba H, Kobayashi N, Hashimoto S, Tsuruya Y, Kubo N, Fujii M, Kawakami M, Saito M, Tsuboi J, Ino T, Kakehashi A. Exercise after heparin administration: A new therapeutic program for patient with arteriosclerosis obliterans. American Heart Association Scientific Sessions 2002 2002.11 Chicago, IL, U.S.A.

Maejima Y, Ueba H, Kuroki M, Yasu T, Kobayashi N, Nabata A, Hashimoto S, Saito M, Kawakami M. Src family kinases and nitric oxide production are required for hepatocyte growth factor-stimulated endothelial cell growth. 12th International Vascular Biology Meeting 2002.05 長野県軽井沢町

Maejima Y, Yasu T, Iwasawa T, Ueba H, Kobayashi N, Hashimoto S, Tsuruya Y, Kubo N, Fujii M, Kuroki M, Kawakami M, Saito M, Tsuboi J, Ino T, Kakehashi A. Exercise after heparin administration, a new therapeutic program for patient with arteriosclerosis obliterans. 第66回日本循環器学会学術集会 2002.04 北海道札幌市

Maejima Y, Ueba H, Kuroki M, Yasu T, Nabata A, Ikeda N, Kobayashi N, Hashimoto S, Saito M, Kawakami M. Nitric oxide production is required for hepatocyte growth factor-stimulated endothelial cell growth. 10th International Symposium of Cardiovascular Pharmacology 2001.03 京都府京都市

前嶋康浩. MLX遺伝子が高安動脈炎の病状進展に及ぼす影響についての検討. 第64回日本脈管学会学術総会:学術委員会企画シンポジウム5 2023.10.27 神奈川県横浜市

前嶋康浩. 高安動脈炎の病態形成における MLX転写因子の関わり. 第64回日本脈管学会学術総会:シンポジウム13 2023.10.27 神奈川県横浜市

前嶋康浩. 糖尿病併存心不全の病態メカニズム 〜ミトコンドリア機能障害を中心に〜. 第38回日本糖尿病合併症学会 2023.10.20 岡山県岡山市

前嶋康浩. がん治療関連心機能障害を克服するための 基礎研究および臨床における取り組み . 第28回国際個別化医療学会学術集会 2023.10.09 東京都千代田区

前嶋康浩. 糖尿病性心筋症の病態における選択的オートファジーの関わり. 第27回日本心不全学会学術集会　 2023.10.08 神奈川県横浜市

前嶋康浩. メカニズムからみた心血管疾患と高尿酸血症の関わり. 第27回日本心不全学会学術集会 2023.10.06 神奈川県横浜市

前嶋康浩. がんプロフェッショナル養成プランが腫瘍循環器学の普及に及ぼす影響についての期待 . 第6回日本腫瘍循環器学会学術集会　 2023.10.01 兵庫県神戸市

前嶋康浩. SGLT2阻害薬の心筋への影響を考える. 日本腎臓学会若手基礎研究フォーラム2023 2023.08.26 東京都千代田区

前嶋康浩. 高安動脈炎の診療におけるPET-CTの役割. 第33回日本心臓核医学会総会・学術大会 2023.06.24 長崎県長崎市

前嶋康浩. MLX遺伝子が高安動脈炎の病状進展に及ぼす影響についての検討. 第64回日本脈管学会学術総会 2023.06.24 神奈川県横浜市

前嶋康浩. CTRCDの分子機序解明の現状. 第9回日本心筋症研究会 2023.05.13 大阪府吹田市

前嶋康浩. 高安動脈炎の診療・研究における最近の進歩. 第70回日本心臓病学会総会・学術大会 2022.09.23 京都府京都市

前嶋康浩. 高安動脈炎の診療におけるPET-CTの役割. 第32回日本心臓核医学会総会・学術大会 2022.06.25 東京都港区

前嶋康浩. SGLT2阻害薬の直接的な心保護作用とその機序についての検討. 第65回日本腎臓学会学術総会 2022.06.11 兵庫県神戸市

前嶋康浩. 高安動脈炎の発症メカニズムについての新たな知見. 第86回日本循環器学会学術集会 2022.03.11 神奈川県横浜市

前嶋康浩. 抗凝固療法と動脈硬化〜基礎研究の知見から〜. 日本不整脈心電学会カテーテルアブレーション関連秋季大会2021スポンサードセミナー3 2021.09.23 神奈川県横浜市

山口洋平, 細川奨, 梶川優介, 前嶋康浩, 磯部光章, 古川哲史, 土井庄三郎. 肺高血圧症進展過程におけるデクスメデトミジンの効果. 第６回日本肺高血圧・肺循環学会学術集会 2021.05.06 Web

前嶋康浩. 急性心筋炎の診断と治療 〜東京における急性心筋炎に対する現状をもとに〜. 第40回東京CCU研究会 　 2020.12.12 東京都中央区

前嶋康浩. 高安動脈炎の診療におけるPET-CTの役割. 第60回日本核医学会学術総会　 2020.11.14 兵庫県神戸市

前嶋康浩. 抗凝固療法と動脈硬化〜基礎研究の知見から〜. 第57回日本臨床生理学会総会 2020.10.18 千葉県千葉市

前嶋康浩. 褐色脂肪組織に発現する転写因子MLXが高安動脈炎の病因に関与している可能性についての検討. 第61回日本脈管学会総会 2020.10.14 神奈川県横浜市

前嶋康浩. 血液腫瘍と腫瘍循環器学の関わり. 第1回東京医科歯科大学血液内科・循環器内科 合同勉強会 2019.12.18 東京都文京区

前嶋康浩. 心不全とCKDを考慮した心房細動の治療戦略. 第23回日本心不全学会学術集会ランチョンセミナー 2019.10.04 広島県広島市

前嶋康浩. オシメルチニブの長期投与中にたこつぼ型心筋症による急性心不全を発症した1例. 第2回日本腫瘍循環器学会学術集会 2019.09.22 北海道旭川市

前嶋康浩. オートファジー制御からみた心不全の病態の解明. 第56回日本臨床分子医学会：スポンサードセミナー3 「オルガネラ・臓器連関を介した組織運命の決定機構」 2019.04.27 愛知県名古屋市

前嶋康浩. Recent Advances in the Diagnosis and Therapeutic Strategy of Takayasu Arteritis. 第83回日本循環器学会学術集 2019.03.30 神奈川県横浜市

前嶋康浩. Onco-cardiology外来開設に向けての取り組み. 平成30年度　キャンサーボード 2019.01.17 東京都文京区

前嶋康浩. 高安動脈炎の診断・治療・研究の最前線. 第250回日本循環器学会関東甲信越地方会 2018.12.08 東京都中央区

前嶋康浩. 血液凝固第X因子による動脈硬化進展作用の機序の解明. 第4回Pan-Pacific Primary Angioplasty Conference 2018.12.01 東京都新宿区

Yasuhiro Maejima. The critical role of protein quality control against heart failure. 第22回日本心不全学会学術集会 2018.10.13 東京都新宿区

Yasuhiro Maejima, Shun Nakagama, Yuka Shiheido-Watanabe, Yusuke Ito, Natsuko Tamura, Kenzo Hirao, Mitsuaki Isobe. SGLT2 inhibitor directly protects oxidative stress-mediated cardiomyocyte injury by suppressing mitochondrial damage-mediated apoptosis . 第22回日本心不全学会学術集会 2018.10.11 東京都新宿区

前嶋康浩. 高安動脈炎:診断と治療の進歩. 第66回日本心臓病学会学術集会 2018.09.09 大阪府大阪市

前嶋康浩. 免疫抑制治療に難渋した難治性高安動脈炎の一例. 第66回日本心臓病学会学術集会 2018.09.08 大阪府大阪市

前嶋康浩. The role of autophagy in the progression of heart failure. Cardiovascular Metabolic Week 2017 2017.12.09 大阪府大阪市

前嶋康浩. 血液凝固第X因子による動脈硬化進展作用の機序の解明. 第68回Blood Vessel Club 2017.04.24 東京都文京区

前嶋康浩、白井康大、篠岡太郎、小西正則、柳下敦彦、秦野雄、梅本朋幸、前田真吾、吉川俊治、佐々木毅、山本貴信、川端美穂子、合屋雅彦、足利貴志、平尾見三、磯部光章. 心室頻拍のコントロールに難渋した肢帯型筋ジストロフィーに伴う心筋症の一例 . 第3回日本心筋症研究会 2017.04.22 岐阜県岐阜市

前嶋康浩. The Critical Role of Autophagy in the Progression of Heart Failure. 第81回日本循環器学会学術集会 2017.03.18 石川県金沢市

前嶋康浩. オートファジーの制御異常による心不全発症機構の解明. 第90回日本薬理学会年会 2017.03.15 長崎県長崎市

前嶋康浩, 磯部光章. 炎症を基盤とした拡張型心筋症に対するリナグリプチンの発症および病状進展抑制効果に関する機序についての研究. 第20回日本適応医学会学術集会 2016.12.17 東京都中央区

Yasuhiro Maejima, Daisuke Tezuka, Kensuke Hirasawa, Mitsuaki Isobe. Clinical Diagnosis and Prognosis of Isolated Cardiac Sarcoidosis, an Inflammation-mediated Cardiomyopathy. 第20回日本心不全学会学術集会 2016.10.07 北海道札幌市

Yasuhiro Maejima, Mitsuaki Isobe, Junichi Sadoshima. GSK3β alleviates cardiac hypertrophy and LV dysfunction through modulation of FoxO1 activity in response to pressure overload. 第20回日本心不全学会学術集会 2016.10.07 北海道札幌市

前嶋康浩. 報告：わが国の心臓移植の現状. 第12回心臓移植セミナー；第80回日本循環器学会学術集会 2016.03.18 宮城県仙台市

前嶋康浩. 高安動脈炎の感受性遺伝子MLXの一塩基多型による発症・病態進展機転への関与についての検討. 第56回日本脈管学会総会 2015.10.30 東京都港区

Yasuhiro Maejima, Yusuke Ito, Natsuko Tamura, Ryo Watanabe, Mitsuaki Isobe. Dipeptidyl peptidase-4 suppression leads to attenuation of cardiac dysfunction caused by autoimmune myocarditis through inhibiting cathepsin-G activity. 第19回日本心不全学会学術集会 2015.10.24 大阪府大阪市

Yasuhiro Maejima, Junichi Sadoshima, Mitsuaki Isobe. Mammalian sterile 20-like kinase-1 inhibits autophagy, thereby compromising protein quality control in the heart . 第79回日本循環器学会学術集会 2015.04 大阪府大阪市

Yasuhiro Maejima, Junichi Sadoshima, Mitsuaki Isobe. Suppression of autophagy by Mst1 exacerbates cardiac dysfunction by deteriorating protein quality control in the Heart . 第31回国際心臓研究学会日本部会 2014.11.29 愛知県名古屋市

Yasuhiro Maejima, Akihiro Shirakabe, Yoshiyuki Ikeda, Peiyong Zhai and Junichi Sadoshima. Dynamin-related protein 1 (Drp1) accumulates in mitochondria and plays a protective role in the heart in response to pressure overload. 第37回日本分子生物学会年会 2014.11.25 神奈川県横浜市

Yasuhiro Maejima, Junichi Sadoshima, Mitsuaki Isobe. Mst1 plays a cell-protective role in the heart through FoxO1 and C/EBP-β phosphorylation. 第18回日本心不全学会学術集会 2014.10.10 大阪府大阪市

前嶋康浩. オートファジー機能異常による心不全発症機構の解明. 第35回日本循環制御医学会総会 2014.07.04 福岡県福岡市

Maejima Y, Isobe M, Sadoshima J. Mst1, a proapoptotic kinase, inhibits autophagy, thereby compromising protein quality control in failing hearts. 第78回日本循環器学会学術集会 2014.03 東京都千代田区

Yasuhiro Maejima, Peiyong Zhai, Mondira Kundu, Junichi Sadoshima, Mitsuaki Isobe. ULK1 plays a critical role in mediating autophagy in response to stress conditions in the heart. 第17回日本心不全学会学術集会 2013.11 埼玉県さいたま市

Maejima Y. Mst1 stimulates cell protective mechanisms of FoxO1 through phophorylation. 第14回日本心不全学会学術集会 2010.10 東京都新宿区

Maejima Y, Isobe M, Sadoshima J. The Mechanism and the Role of Aging in Cardiomyocytes . 第74回日本循環器学会学術集会 2010.03 京都府京都市

前嶋康浩，岡田寛之，小内靖之，磯部和哉，鈴木淳一，磯部光章. Telmisartanはangiotensin II受容体拮抗作用とPPARγ活性化作用の両者を介して心筋梗塞後の左室リモデリングを抑制する. 第48回日本脈管学会学術集会 2007.10 長野県松本市

Maejima Y, Adachi S, Isobe K, Ito H, Isobe M. Combined treatment of angiotensin receptor blocker and HMG-CoA reductase inhibitor synergistically improves cardiac dysfunction in Dahl rats. 第24回国際心臓研究学会日本部会学術集会 2007.06 Ferrara, Italy

Maejima Y, Adachi S, Isobe K, Ito H, Isobe M. Simvastatin Enhances Beneficial Effects of Losartan on Myocardial dysfunction of Salt-Sensitive Hypertensive Rats, via Pleiotropic Effects. 第71回日本循環器学会学術集会 2007.03 神奈川県横浜市

Maejima Y, Suzuki J, Kosuge H, Inagaki H, Kawabata M, Hachiya H, Hata A, Hirao K, Isobe M. Beneficial effects of HMG-CoA reductase inhibitors (statin) in patients with nonischemic heart failure treated with angiotensin II blockade. 第70回日本循環器学会学術集会 2006.03 愛知県名古屋市

Maejima Y, Adachi S, Tamamori-Adachi M, Nobori K, Ito H, Isobe M. Nitric oxide inhibits hypoxia-reoxygenation-induced myocardial apoptosis by suppression of cyclin A-associated kinase activity. 第6回日本心不全学会学術集会 2002.10 東京都新宿区

Maejima Y, Adachi S, Tamamori-Adachi M, Nobori K, Ito H, Isobe M. Nitric oxide inhibits ischemia/reperfusion-induced myocardial apoptosis by suppression of cyclin A-associated kinase activity. 第66回日本循環器学会学術集会 2002.04 北海道札幌市

前嶋康浩, 上羽洋人, 安隆則, 名畑あおい, 黒木昌寿, 齋藤宗靖, 川上正舒. 肝細胞増殖因子による血管内皮細胞の増殖制御：NOとSrcの役割. 第33回日本動脈硬化学会学会学術集会 2001.05 東京都港区

Maejima Y, Yasu T, Matsushima K, Sugawara Y, Tsuruya Y, Hasimoto S, Kubo N, Omura N, Fujii M, Saito M. Long-term prognosis of fulminant myocarditis rescued by percutaneous cardiopulmonary support device. 第65回日本循環器学会学術集会 2000.03

前嶋康浩、岸一馬、川畑雅照、坪井永保、成井浩司、本間栄、中谷龍王、中田紘一郎. 腸骨静脈圧迫症に伴う肺塞栓症の一例. 第134回日本呼吸器学会関東地方会 1999.05 東京都新宿区

前嶋康浩、田上哲夫、乳原善文、北村曜子、白矢勝子、柳秀高、中村成男、香取秀幸、 横田雅史、松下芳雄、横山啓太郎、竹本文美、原茂子、山田明、遠藤雄三. 多発性嚢胞腎にネフローゼ症候群を合併した一例. 第28回日本腎臓学会東部学術大会 1998.09 神奈川県横浜市

前嶋康浩、服部健、池田修一、高林康樹、関島良樹、徳田隆彦、進藤政臣、柳澤信夫. 肺腫瘤に著明な胸水貯留を伴ったALアミロイドーシスの一例. 第99回日本内科学会信越地方会 1996.10 長野県松本市