Personnel Information

写真a

IMAI Kohsuke


Job title

Associate Professor

Homepage URL

http://www.tmd.ac.jp/med/ped/

Research Areas, Keywords

Primary immunodeficiency

Graduating School 【 display / non-display

  • Tokyo Medical and Dental University, Faculty of Medicine, 1992.03, Graduated

Graduate School 【 display / non-display

  • Tokyo Medical and Dental University, Graduate School, Division of Medical Sciences, Doctor's Course, 1999.03, Completed

Campus Career 【 display / non-display

  • 1992.06
    -
    1992.08
    Tokyo Medical and Dental University, Medical Hospital, Hospital Departments, Department of Pediatrics, Maternal and Woman's Medicine, Pediatrics, Trainee Resident
  • 1994.02
    -
    1994.03
    Tokyo Medical and Dental University, Medical Hospital, Hospital Departments, Department of Pediatrics, Maternal and Woman's Medicine, Pediatrics, Senior Resident
  • 1999.04
    -
    2000.09
    Tokyo Medical and Dental University, Medical Hospital, Hospital Departments, Department of Pediatrics, Maternal and Woman's Medicine, Pediatrics, Senior Resident
  • 2011.08
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Endowed Departments, Department of Pediatrics, Perinatal and Maternal Medicine, Associate Professor
  • 2011.08
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Environmental Response, Pediatrics and Developmental Biology, Project Associate Professor

External Career 【 display / non-display

  • 2001.07
    -
    2004.07
    , Project Researcher
  • 2006.04
    -
    2008.09
    , Junior Associate Professor
  • 2008.10
    -
    2011.07
    , Associate Professor
  • 2011.08
    -
    Now
    , Visiting Lecturer

Academic Activity 【 display / non-display

  • 2012
    -
    2015
    Mid-Winter Seminar Tutor
  • 2012
    -
    2018
    Pediatric international

Research Areas 【 display / non-display

  • Human genetics

  • Pediatrics

  • Immunology

Qualification Acquired 【 display / non-display

  • Doctor

 

Research Theme 【 display / non-display

  • Establishment of newborn screening of primary immunodeficiency (PID) in Japan, 2004.08 - Now

  • Understanding the molecular mechanism of immunoglobulin class switch recombination and antibody production through the genetic analysis of the causative gene of hyper-IgM syndrome, combined immunodeficiency, CVID and B cell deficiency, 2001.07 - Now

  • Genetic diagnosis and clinical database construction of the PID patients, 1994.04 - Now

  • Hematopoietic stem cell transplantation and gene therapy for PID, 1994.04 - Now

Published Papers & Misc 【 display / non-display

  • Miyamoto S, Umeda K, Kurata M, Nishimura A, Yanagimachi M, Ishimura M, Sato M, Shigemura T, Kato M, Sasahara Y, Iguchi A, Koike T, Takahashi Y, Kajiwara M, Inoue M, Hashii Y, Yabe H, Kato K, Atsuta Y, Imai K, Morio T.. Hematopoietic Cell Transplantation for Severe Combined Immunodeficiency Patients: a Japanese Retrospective Study. J Clin Immunol. 2021.08; ( PubMed, DOI )

  • Akira Nishimura, Yuki Aoki, Yasuyoshi Ishiwata, Takuya Ichimura, Junichi Ueyama, Yuta Kawahara, Takahiro Tomoda, Maiko Inoue, Kazuaki Matsumoto, Kento Inoue, Haruka Hiroki, Shintaro Ono, Motoi Yamashita, Tsubasa Okano, Mari Tanaka-Kubota, Miho Ashiarai, Satoshi Miyamoto, Reiji Miyawaki, Chika Yamagishi, Mari Tezuka, Teppei Okawa, Akihiro Hoshino, Akifumi Endo, Masato Yasuhara, Takahiro Kamiya, Noriko Mitsuiki, Toshiaki Ono, Takeshi Isoda, Masakatsu Yanagimachi, Daisuke Tomizawa, Masayuki Nagasawa, Shuki Mizutani, Michiko Kajiwara, Masatoshi Takagi, Hirokazu Kanegane, Kohsuke Imai, Tomohiro Morio. Hematopoietic Cell Transplantation with Reduced Intensity Conditioning Using Fludarabine/Busulfan or Fludarabine/Melphalan for Primary Immunodeficiency Diseases. J Clin Immunol. 2021.07; 41 (5): 944-957. ( PubMed, DOI )

  • Tsubasa Okano, Akira Nishimura, Kento Inoue, Takuya Naruto, Shown Tokoro, Takahiro Tomoda, Takahiro Kamiya, Asami Simbo, Yuko Akutsu, Keisuke Okamoto, Tzuwen Yeh, Takeshi Isoda, Masakatsu Yanagimachi, Michiko Kajiwara, Kohsuke Imai, Hirokazu Kanegane, Masaaki Mori, Tomohiro Morio, Masatoshi Takagi. Somatic mutation in RUNX1 underlies mucocutaneus inflammatory manifestations. Rheumatology (Oxford). 2021.09; ( PubMed, DOI )

  • Imanaka Y, Taniguchi M, Doi T, Tsumura M, Nagaoka R, Shimomura M, Asano T, Kagawa R, Mizoguchi Y, Karakawa S, Arihiro K, Imai K, Morio T, Casanova JL, Puel A, Ohara O, Kamei K, Kobayashi M, Okada S. . Inherited CARD9 Deficiency in a Child with Invasive Disease Due to Exophiala dermatitidis and Two Older but Asymptomatic Siblings. J Clin Immunol. 2021.07; 41 (5): 975-986. ( PubMed, DOI )

  • Yamashita M, Kuehn HS, Okuyama K, Okada S, Inoue Y, Mitsuiki N, Imai K, Takagi M, Kanegane H, Takeuchi M, Shimojo N, Tsumura M, Padhi AK, Zhang KYJ, Boisson B, Casanova JL, Ohara O, Rosenzweig SD, Taniuchi I, Morio T.. A variant in human AIOLOS impairs adaptive immunity by interfering with IKAROS. Nat Immunol. 2021.07; 22 (7): 893-903. ( PubMed, DOI )

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Conference Activities & Talks 【 display / non-display

  • Imai K.. Newly reported primary antibody deficiencies (PADs). Chinese PID Summer School 2021.09.24 Shenzhen/Web

  • Imai K.. Severe Combined Immunodeficiency (SCID). APSID Summer Webinar 2021 2021.06.16 web

  • Discriminant analysis of primary immunodeficiency using Recognizing Textual Entailment AI. 2021.02.07

  • Diagnosis and Treatment for LOCID(Late onset combined immunodeficiency) . 2021.02.06

  • Delayed recovery of chimeric status after non-myeloablative cord blood transplantation in a patient with DNA ligase IV deficiency. 2021.02.06

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Others 【 display / non-display

  • Human Lifelong Immunity Depends on APRIL(Kohsuke Imai),2020.06

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