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KOBAYAKAWA Takuya
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Graduating School 【 display / non-display 】
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Waseda University, School of Advance Science and Engineering, Department of Applied Chemistry, 2012.03, Graduated
Graduate School 【 display / non-display 】
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Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Science and Technology Track, Master's Course, 2014.03, Completed
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Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Life Science and Technology Track, Doctor's Course, 2017.03, Completed
Degree 【 display / non-display 】
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Doctor (Engineering), Tokyo Medical and Dental University
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Master (Engineering), Tokyo Medical and Dental University
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Bachelor (Engineering), Waseda University
Campus Career 【 display / non-display 】
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2012.04-2014.03Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Science and Technology, Graduate Student
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2014.04-2017.03Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Life Science and Technology, Life Science and Technology, Medicinal Chemistry, Graduate Student
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2017.04-2017.09Tokyo Medical and Dental University, Institute of Biomaterials and Bioengineering, Biomolecular Chemistry, Medicinal Chemistry, Junior Associate Professor
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2017.10-NowTokyo Medical and Dental University, Institute of Biomaterials and Bioengineering, Biomolecular Chemistry, Medicinal Chemistry, Assistant Professor
External Career 【 display / non-display 】
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2014.04-2016.03Tokyo Medical and Dental University, Institute of Biomaterials and Bioengineering, Research Assistant
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2015.04-2016.03Tokyo Kasei University,
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2016.04-2017.03Japan Society for the Promotion of Science, Research Fellowships for Young Scientists, Research Fellowships for Young Scientists
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2017.04-2017.09Japan Society for the Promotion of Science, Research Fellowships for Young Scientists, Research Fellowships for Young Scientists
Academic Society Affiliations 【 display / non-display 】
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The Pharmaceutical Society of Japan
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Japanese Society for Chemical Biology
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The Society of Synthetic Organic Chemistry, Japan
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The Japanese Peptide Society
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American Chemical Society
Academic Activity 【 display / non-display 】
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2013.06The 8th Annual Meeting of Japanese Society for Chemical Biology The 8th Annual Meeting of Japanese Society for Chemical Biology, Cooperation Staff
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2017.10-NowInstitute of Biomaterials and Bioengineering, Tokyo Medical and Dental University Open Campus Committee
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2018.06The 13th Annual Meeting of Japanese Society for Chemical Biology The 13th Annual Meeting of Japanese Society for Chemical Biology, Cooperation Staff
Research Areas 【 display / non-display 】
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Chemical pharmacy
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Organic chemistry
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Synthetic chemistry
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Drug development chemistry
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Chemical biology
Qualification Acquired 【 display / non-display 】
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Hazardous Material Handler (first kind)
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Usual Car License (first kind)
Published Papers & Misc 【 display / non-display 】
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Tsuji K, Owusu KB, Kobayakawa T, Wang R, Fujino M, Kaneko M, Yamamoto N, Murakami T, Tamamura H. Exploratory studies on CA-15L, an anti-HIV active HIV-1 capsid fragment. Bioorganic & medicinal chemistry. 2020.06; 28 (11): 115488. ( PubMed, DOI )
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Takuya Kobayakawa, Hikaru Takano, Takahiro Ishii, Kohei Tsuji, Nami Ohashi, Wataru Nomura, Toshiaki Furuta, Hirokazu Tamamura. Synthesis of hydrophilic caged DAG-lactones for chemical biology applications. Organic & biomolecular chemistry. 2020.05; ( PubMed, DOI )
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Maeda Kenji, Matsuda Kouki, Islam Saiful, Kobayakawa Takuya, Tsuchiya Kiyoto, Hattori Shin-ichiro, Gatanaga Hiroyuki, Oka Shinichi, Yoshimura Kazuhisa, Tamamura Hirokazu, Mitsuya Hiroaki, Satou Yorifumi. HIV持続潜伏感染に関する最先端研究(Treatment of HIV-1-reservoirs using latency-reversing agents(LRAs) toward HIV cure) 日本エイズ学会誌. 2019.11; 21 (4): 314. ( ichushi )
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Takuya Kobayakawa, Hirokazu Tamamura. Development for peptidomimetic chemistry based on chloroalkene structures Journal of Synthetic Organic Chemistry, Japan. 2019.09; 77 (9): 904-911.
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Takuya Kobayakawa, Kento Ebihara, Yuzuna Honda, Masayuki Fujino, Wataru Nomura, Naoki Yamamoto, Tsutomu Murakami, Hirokazu Tamamura. Dimeric C34 Derivatives Linked through Disulfide Bridges as New HIV-1 Fusion Inhibitors. Chembiochem. 2019.08; 20 (16): 2101-2108. ( PubMed, DOI )
Books etc 【 display / non-display 】
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The Frontier of Peptide Drug Discovery. 2019.05 (ISBN : 978-4-7813-1417-4)
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Synthesis Technology of Peptides, Nucleic Acids and Sugar Chains for Medium Molecule Drug Discovery. CMC Publishing Co.,Ltd., 2018.02 (ISBN : 978-4-7813-1320-7)
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Hirokazu Tamamura, Takuya Kobayakawa, Nami Ohashi. Mid-size Drugs Based on Peptides and Peptidomimetics. Springer Singapore, 2018.01 (ISBN : 978-981-10-7691-6)
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Takuya Kobayakawa, Tetsuo Narumi, Hirokazu Tamamura. Stereoselective Synthesis of Chloroalkene Dipeptide Isosteres Utilizing Organocopper Reagents. The Japanese Peptide Society, 2016.03
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Takuya Kobayakawa, Tetsuo Narumi, Hirokazu Tamamura. Development of Efficient Synthetic Methodologies of Chloroalkene Dipeptide Isosteres. in "Peptide Science 2014," ed. by Akira Otaka, The Japanese Peptide Society, Osaka. The Japanese Peptide Society, 2015.03
Conference Activities & Talks 【 display / non-display 】
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Kofi Baffour-Awuah Owusu, Kohei Tsuji, Rongyi Wang, Takuya Kobayakawa, Moemi Kaneko, Tsutomu Murakami, Hirokazu Tamamura. Exploratory studies on the development of anti-HIV-1 peptides based on HIV-1 capsid fragments. 第57回ペプチド討論会 2020.11.10 online
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Wataru Nomura, Takumi Kamimura, Takuya Kobayakawa, Hirokazu Tamamura. Endogenous protein expression imaging by fluorogenic ZIP tag-probe system. 第57回ペプチド討論会 2020.11.10 online
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Chika Azuma, Takuya Kobayakawa, Kohei Tsuji, Hirokazu Tamamura. A convergent synthesis of chloroalkene dipeptide isosteres as peptidomimetics. 第57回ペプチド討論会 2020.11.09 online
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Tsutomu Murakami, Kento Ebihara, Takuya Kobayakawa, Masayuki Fujino, Eiichi Kodama, Hirokazu Tamamura. Elucidation of mechanism of HIV-1 fusion inhibitors developed by dimerization strategy. The 67th Annual Meeting of the Japanese Society for Virology 2019.10.29 Tokyo
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Kouki Matsuda, Takuya Kobayakawa, Kiyoto Tsuchiya, Shin-ichiro Hattori, Hiroyuki Gatanaga, Kazuhisa Yoshimura, Shinichi Oka, Yasuyuki Endo, Hirokazu Tamamura, Hiroaki Mitsuya, Kenji Maeda. Benzolactam protein kinase C activators promote apoptosis of HIV-infected human cells via HIV latency reversal. The 67th Annual Meeting of the Japanese Society for Virology 2019.10.29 Tokyo
Campus class subject 【 display / non-display 】
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Practical Chemical Biology,2018 - Now
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Development of Functional Molecules,2018 - Now
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Introduction to Chemistry and Biology of Biofunctional Molecules,2018 - Now
External class subject 【 display / non-display 】
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,Tokyo Kasei University
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,Tokyo Kasei University
Performance of duties 【 display / non-display 】
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,2020.01
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,2019.01
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,2019.01
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,2019.01
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,2018.08
Social Contribution 【 display / non-display 】
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Frontier Research on Medicinal Chemistry of Mid-sized Molecules,Kanazawa, Japan,2018.03.28