講演・口頭発表等 - 三宅　健介

41. Sho Shibata, Kensuke Miyake, Soichiro Yoshikawa, Yohei Kawano, Yoshinori Yamanishi, Hajime Karasuyama. Monocyte-derived macrophages in the lung contribute to the development of pulmonary emphysema through MMP12 production in a mouse model of COPD. The 46th Annual Meeting of The Japanese Society for Immunology 2017.12.12 Sendai, Japan

42. Soichiro Yoshikawa, Masatsugu Oh-hora, Kensuke Miyake, Yohei Kawano, Yoshinori Yamanishi, Hajime Karasuyama. Prolonged Ca2+ influx via STIM2 is essential for cytokine-induced IL-4 production in basophil. The 46th Annual Meeting of The Japanese Society for Immunology 2017.12.12 Sendai, Japan

43. SHIBATA Sho, MIYAKE Kensuke, YOSHIKAWA Soichiro, KAWANO Yohei, YAMANISHI Yoshinori, KARASUYAMA Hajime. COPDマウスモデルにおいて肺の単球由来マクロファージはMMP-12産生を通して肺気腫の発生に関与する(Allergy: Lower airway allergic inflammation　Monocyte-derived macrophages in the lung contribute to the development of pulmonary emphysema through MMP-12 production in a mouse model of COPD). 日本免疫学会総会・学術集会記録 2017.12.01

44. NAGAO Toshihisa, TERANISHI Mio, MIYAKE Kensuke, YOSHIKAWA Soichiro, KAWANO Yohei, YAMANISHI Yoshinori, KARASUYAMA Hajime. 顆粒球及びマスト細胞　担体タンパク質の糖修飾によりアレルゲンはIgEおよび好塩基球媒介性のアレルギー性炎症誘発能を獲得する(Granulocyte & Mast cells　Sugar modification of carrier protein confers ability on allergen to induce IgE- and basophil-mediated allergic inflammation). 日本免疫学会総会・学術集会記録 2017.12.01

45. Miyake Kensuke, Shiozawa Nozomu, Nagao Toshihisa, Yoshikawa Soichiro, Yamanishi Yoshinori, Karasuyama Hajime. 顆粒球及びマスト細胞　好塩基球はトロゴサイトーシスを介して樹状細胞(DC)由来のペプチドMHCクラスII複合体を獲得し抗原を提示する(Granulocyte & Mast cells　Basophils exert antigen presentation via trogocytosis-mediated acquisition of peptide-MHC class II complexes from dendritic cells(DCs)). 日本免疫学会総会・学術集会記録 2017.12.01

46. Yamanishi Yoshinori, Iki Misako, Tanaka Kensei, Deki Hayato, Fujimaki Mio, Miyake Kensuke, Yoshikawa Soichiro, Kawano Yohei, Sato Shingo, Karasuyama Hajime. アレルギー(3)　アレルギー性皮膚炎、食物アレルギー、アレルギー性結膜炎　IgE媒介性遅発性アレルギー性炎症において好塩基性tryptase mMCP-11は極めて重要な役割を果たす(Allergy: Allergic dermatitis, food allergy and allergic conjunctivitis　Basophil tryptase mMCP-11 plays a crucial role in IgE-mediated, delayed-onset allergic inflammation). 日本免疫学会総会・学術集会記録 2017.12.01

47. Yoshikawa Soichiro, Oh-hora Masatsugu, Miyake Kensuke, Kawano Yohei, Yamanashi Yoshinori, Karasuyama Hajime. アレルギー(2)　上気道アレルギー性炎症とアレルギー反応　好塩基球におけるSTIM2を介した長期間にわたるCa2+の流入はサイトカイン誘導IL-4産生にとって不可欠である(Allergy: Upper airway allergic inflammation and allergic responses　Prolonged Ca2+ influx via STIM2 is essential for cytokine-induced IL-4 production in basophil). 日本免疫学会総会・学術集会記録 2017.12.01

48. Kensuke Miyake, Nozomu Shiozawa, Toshihisa Nagao, Moe Kawawa, Soichiro Yoshikawa, Yoshinori Yamanishi, Hajime Karasuyama. Basophils gain the capacity of antigen presentation by acquiring MHC class II molecules from dendritic cells through trogocytosis. The 45th Annual Meeting of The Japanese Society for Immunology 2016.12.06 Okinawa, Japan

49. Nagao, T., Takahashi, S., Kawawa, M., Miyake, K., Yoshikawa, S., Yamanishi, Y., Karasuyama, H.. Sugar modification of carrier protein in allergen determines the magnitude of IgE- and basophil-mediated allergic inflammation. 16th International Congress of Immunology 2016.08.23 Melbourne, Australia

50. Miyake K., Shiozawa N., Nagao T., Yoshikawa S., Yamanishi Y., Karasuyama H.. Basophils gain the capacity of antigen presentation through the import of MHC class II molecules from dendritic cells. 16th International Congress of Immunology 2016.08.23 Melbourne, Australia

51. Kensuke Miyake, Nozomu Shiozawa, Toshihisa Nagao, Soichiro Yoshikawa, Yoshinori Yamanishi, Hajime Karasuyama. Basophils acquire MHC class II molecules from DCs and exert antigen presenting capacity. The 44th Annual Meeting of The Japanese Society for Immunology 2015.11.18 Sapporo, Japan

52. Nagao T, Takahashi S, Kawawa M, Miyake K, Yoshikawa S, Sato S, Yamanishi Y, Karasuyama H.. Molecular properties of carrier protein in allergen are critical for the development of IgE-mediated chronic allergic inflammation in the skin: what makes a foreign material to be an allergen?. The 44th Annual Meeting of The Japanese Society for Immunology 2015.11.18 Sapporo, Japan

53. Kensuke Miyake, Toshihisa Nagao, Yuto Yahagi, Soichiro Yoshikawa, Yoshinori Yamanishi, Hajime Karasuyama. GM-CSF can promote MHC class II expression and ability of antigen presentation in basophils. The 64th Meeting of Japanese Society of Allergology 2015.05.26 Tokyo, Japan

54. MIYAKE Kensuke, NAGAO Toshihisa, YAHAGI Yuto, NUMAZAKI Takumi, YOSHIKAWA Soichiro, YAMANISHI Yoshinori, KARASUYAMA Hajime. GM-CSF-elicited basophils have increased capacity for antigen presentation.. The 43rd Annual Meeting of The Japanese Society for Immunology 2014.12.10 Kyoto, Japan

55. 三宅健介. 希少な免疫細胞である好塩基球のアトピー性皮膚炎における役割. 第54回日本皮膚免疫アレルギー学会学術大会 2024.12.21 郡山、日本

56. 三宅健介. 1細胞解析によって解明された好塩基球の炎症制御機構. 順天堂大学アトピー疾患研究センター・国立成育医療研究センター　合同シンポジウム 2024.12.01 順天堂大学

57. 伊藤潤哉、三宅健介、千葉朋希、浅原弘嗣、烏山一. RNA結合タンパク質Tristetraprolin（TTP）は好塩基球の活性化を抑制する. 第73回日本アレルギー学会学術大会 2024.10.19

58. 三宅健介. シングルセルRNAシーケンス解析の活用による好塩基球の皮膚アレルギー制御機構の解明. 第73回日本アレルギー学会学術大会 2024.10.18 京都、日本

59. 三宅健介. アレルギーにおける好塩基球の役割～アトピー性皮膚炎における役割を中心に～. 第73回日本アレルギー学会学術大会 2024.10.18 京都、日本

60. 三宅　健介. Single-cell transcriptomics identifies the differentiation trajectory from inflammatory monocytes to pro-resolving macrophages in a mouse skin allergy model. 第19回血液学若手研究者勉強会（麒麟塾） 2024.06.29 東京