Personnel Information

写真a

HIRATE Yoshikazu


Job title

Junior Associate Professor

Homepage URL

http://www.tmd-cea.jp/eam/en/

Research Areas, Keywords

Developmental biology, Developmental Engineering, Reproductive biology
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Campus Career 【 display / non-display 】

  • 2014.10
    -
    2017.03
    Tokyo Medical and Dental University， Research and Industry-University Alliance Organization， Center for Experimental Animal， Junior Associate Professor
  • 2014.04
    -
    Now
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Advanced Therapeutic Sciences， Experimental Animal Model for Human Disease， Junior Associate Professor
  • 2014.04
    -
    2014.09
    Tokyo Medical and Dental University， Joint Institutes for Education and Research， Center for Experimental Animal， Junior Associate Professor
  • 2017.04
    　
    　
    Tokyo Medical and Dental University， Institute of Research， Research Facility Cluster， Center for Experimental Animal， Junior Associate Professor
  • 2017.05
    -
    Now
    Tokyo Medical and Dental University， Institute of Research， Research Facility Cluster， Center for Experimental Animal， Junior Associate Professor
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External Career 【 display / non-display 】

  • 2006.01
    -
    2009.03
    Fred Hutchinson Cancer Research Center, Postdoctoral Research Fellow
  • 2011.04
    -
    2014.03
    , Assistant Professor
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Research Areas 【 display / non-display 】

  • Developmental biology

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Published Papers & Misc 【 display / non-display 】

  • Miura Kento, Harikae Kyoko, Nakaguchi Mayu, Imaimatsu Kenya, Hiramatsu Ryuji, Tomita Ayako, Hirate Yoshikazu, Kanai-Azuma Masami, Kurohmaru Masamichi, Ogura Atsuo, Kanai Yoshiakira. Molecular and genetic characterization of partial masculinization in embryonic ovaries grafted into male nude mice PLOS ONE. 2019.03; 14 (3): e0212367. ( PubMed, DOI )

  • Hirate Y. Technological innovation in mouse developmental engeneering Biomedical gerontology. 2018.09; 42 (3): 31-36.

  • Hitomi Igarashi, Mami Uemura, Ryuji Hiramatsu, Ryuto Hiramatsu, Saki Segami, Montri Pattarapanawan, Yoshikazu Hirate, Yuki Yoshimura, Haruo Hashimoto, Hiroki Higashiyama, Hiroyuki Sumitomo, Masamichi Kurohmaru, Yukio Saijoh, Hiroshi Suemizu, Masami Kanai-Azuma, Yoshiakira Kanai. Sox17 is Essential for Proper Formation of the Marginal Zone of Extraembryonic Endoderm Adjacent to a Developing Mouse Placental Disk. Biology of Reproduction. 2018.04; ( PubMed, DOI )

  • Hirate Yoshikazu, Hayakawa Kana, Toyomura Yuga, Igarashi Hitomi, Miura Kento, Kanai Yoshiakira, Kanai-Azuma Masami. Sox17ハプロ不全による着床異常マウスにおける子宮上皮遺伝子の発現変化(Expression changes in uterine epithelial genes in implantation-defective mice due to Sox17 haploinsufficiency) Experimental Animals. 2017.06; 66 (Suppl.): S101. ( ichushi )

  • Hiroki Higashiyama, Aisa Ozawa, Hiroyuki Sumitomo, Mami Uemura, Ko Fujino, Hitomi Igarashi, Kenya Imaimatsu, Naoki Tsunekawa, Yoshikazu Hirate, Masamichi Kurohmaru, Yukio Saijoh, Masami Kanai-Azuma, Yoshiakira Kanai. Embryonic cholecystitis and defective gallbladder contraction in the Sox17-haploinsufficient mouse model of biliary atresia. Development. 2017.05; 144 (10): 1906-1917. ( PubMed, DOI )

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Conference Activities & Talks 【 display / non-display 】

  • Yoshikazu Hirate, Yuki Nakano, Tatsumi Yoshida, Dania Badran, Hikaru Ito, Mami Uemura, Yoshiakira Kanai, and Masami Kanai-Azuma. Attempt for uterine epithelial replacement by TRECK-induced selective cell death and cell transplantation. The 32nd Molossinus colloquium 2019.06.27 Chiba, Japan

  • Yoshikazu Hirate, Yuki Nakano, Tatsumi Yoshida, Hikaru Ito, Mami Uemura, Yoshiakira Kanai, and Masami Kanai-Azuma. Establishment of a TRECK-based approach for replacement of uterine endometrial epithelium. The 66th Annual Meeting of Japanese Association for Laboratory Animal Science 2019.05.16 Fukuoka, Japan

  • Yoshikazu Hirate, Hitomi Takahashi, Yoshiaki Ito, Jinling Li, Chiho Otsuka, Hiroshi Asahara, Ruby Yanru Chen-Tsai, Masami Kanai-Azuma. Site-directed transgenic mice production using TARGATT™ knock-in technology in TMDU. The 15th Transgenic Technology Meeting (TT2019) 2019.04.08 Kobe, Hyogo, Japan

  • Yoshikazu Hirate, Kana Hayakawa, Yuki Nakano, Shiori Kumazawa, Mami Uemura, Kento Miura, Yoshiakira Kanai, Masami Kanai-Azuma. Involvement of uterine SOX17 in blastocyst attachment and decidualization. The 41st Annual Meeting of the Molecular Biology Society of Japan 2018.11.30 Pacifico Yokohama

  • Hirate Y, Hayakawa K, Nakano Y, Uemura M, Miura K, Kanai Y, Kanai-Azuma M. Identification of downstream genes of the uterine SOX17 around the receptive period. The 65th Annual Meeting of Japanese Association for Laboratory Animal Science 2018.05.17 Toyama Prefectural Civic Center

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