Personnel Information

写真a

TSUCHIYA Yosuke


Job title

Assistant Professor
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Graduating School 【 display / non-display 】

  • Tokyo Medical and Dental University, 2020.09, Graduated

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Campus Career 【 display / non-display 】

  • 2015.04
    -
    2020.09
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Matrix， Periodontology， Graduate Student
  • 2020.10
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    2022.03
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Matrix， Periodontology， Dental Resident
  • 2022.04
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    2024.09
    Tokyo Medical and Dental University， Tokyo Medical and Dental University， Division of Clinical Dentistry， Department of Conservative Dentistry， Periodontics， Project Assistant Professor
  • 2022.04
    -
    Now
    Institute of Science Tokyo， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Matrix， Periodontology， Project Assistant Professor
  • 2024.10
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    2025.08
    Institute of Science Tokyo， -， Institute of Science Tokyo Hospital， Department of Conservative Dentistry， Periodontics， Project Assistant Professor
  • 2025.09
    -
    Now
    Institute of Science Tokyo， -， Institute of Science Tokyo Hospital， Department of Conservative Dentistry， Periodontics， Assistant Professor

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Research Areas 【 display / non-display 】

  • Conservative dentistry

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Research Theme 【 display / non-display 】

  • The mechanisms of occlusal trauma focusing on mechanosensing by osteocyte, 2020.09 - 2022.03

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Published Papers & Misc 【 display / non-display 】

  1. Lin P, Tsuchiya Y, Katagiri S, Ohsugi Y, Toyoshima K, Hirota T, Niimi H, Shimohira T, Iwata T, Aoki A. Effects of Erbium-Doped Yttrium Aluminum Garnet Laser Irradiation on the Proliferation and Alteration of Gene Expression in MLO-Y4 Osteocyte-like Cells Photobiomodul Photomed Laser Surg. 2025.10; ( DOI )

  2. Evaluation of Trypsin-Like Enzyme Activity Using a Novel Device for Monitoring Porphyromonas gingivalis in Periodontal Pockets: A Pilot Study. 2025.05; 17 (5): e83832. ( PubMed, DOI )

  3. Morita Kazuki, Nakayama Masamichi, Wang Jiacheng, Onizuka Satoru, Hatasa Masahiro, Ohsugi Yujin, Tsuchiya Yosuke, Niimi Hiromi, Liu Anhao, Sakai Hideaki, Okano Teruo, Iwata Takanori. 調整可能な細胞剥離性を有する温度応答性培養皿を用いた生体移植可能な歯根膜由来間葉系幹細胞シートの安定的な調製(Stable preparation of in vivo transplantable periodontal ligament-derived mesenchymal stem cell sheets in thermoresponsive culture dishes with tunable cell detachability) Regenerative Therapy. 2025.03; 28 345-357. ( ichushi )

  4. Stable preparation of in vivo transplantable periodontal ligament-derived mesenchymal stem cell sheets in thermoresponsive culture dishes with tunable cell detachability. 2025.03; 28 345-357. ( PubMed, DOI )

  5. Fam102a translocates Runx2 and Rbpjl to facilitate Osterix expression and bone formation. 2025.01; 16 (1): 9. ( PubMed, DOI )

  6. Lin P, Liu A, Tsuchiya Y, Noritake K, Ohsugi Y, Toyoshima K, Tsukahara Y, Shiba T, Nitta H, Aoki A, Iwata T, Katagiri S. Association between periodontal disease and chronic obstructive pulmonary disease Japanese Dental Science Review. 2023.12; 59 389-402. ( PubMed, DOI )

  7. Lin Peiya, Liu Anhao, Tsuchiya Yosuke, Noritake Kanako, Ohsugi Yujin, Toyoshima Keita, Tsukahara Yuta, Shiba Takahiko, Nitta Hiroshi, Aoki Akira, Iwata Takanori, Katagiri Sayaka. 歯周病と慢性閉塞性肺疾患の関連性(Association between periodontal disease and chronic obstructive pulmonary disease) The Japanese Dental Science Review. 2023.12; 59 389-402. ( ichushi )

  8. Toyoshima, K; Ohsugi, Y; Lin, PY; Komatsu, K; Shiba, T; Takeuchi, Y; Hirota, T; Shimohira, T; Tsuchiya, Y; Katagiri, S; Iwata, T; Aoki, A. Blue Light-Emitting Diode Irradiation Without a Photosensitizer Alters Oral Microbiome Composition of Ligature-Induced Periodontitis in Mice PHOTOBIOMODULATION PHOTOMEDICINE AND LASER SURGERY. 2023.10; 41 (10): 549-559. ( PubMed, DOI )

  9. Ohsugi Y, Hatasa M, Katagiri S, Hirota T, Shimohira T, Shiba T, Komatsu K, Tsuchiya Y, Fukuba S, Lin P, Toyoshima K, Maekawa S, Niimi H, Iwata T, Aoki A. High-frequency pulsed diode laser irradiation inhibits bone resorption in mice with ligature-induced periodontitis Journal of Clinical Periodontology. 2022.07; e-pub (12): 1275-1288. ( PubMed, DOI )

  10. Yoshida S, Hatasa M, Ohsugi Y, Tsuchiya Y, Liu A, Niimi H, Morita K, Shimohira T, Sasaki N, Maekawa S, Shiba T, Hirota T, Okano T, Hirose A, Ibi R, Noritake K, Tomiga Y, Nitta H, Suzuki T, Takahashi H, Miyasaka N, Iwata T, Katagiri S. Porphyromonas gingivalis administration induces gestational obesity, alters gene expression in the liver and brown adipose tissue in pregnant mice, and causes underweight in fetuses Frontiers in Cellular and Infection Microbiology. 2022.01; 11 745117. ( PubMed, DOI )

  11. Lin P, Niimi H, Ohsugi Y, Tsuchiya Y, Shimohira T, Komatsu K, Liu A, Shiba T, Aoki A, Iwata T, Katagiri S. Application of Ligature-Induced Periodontitis in Mice to Explore the Molecular Mechanism of Periodontal Disease International Journal of Molecular Sciences. 2021.08; 22 (16): 8900. ( PubMed, DOI )

  12. Shimohira T, Niimi H, Ohsugi Y, Tsuchiya Y, Morita K, Yoshida S, Hatasa M, Shiba T, Kadokura H, Yokose S, Katagiri S, Iwata T, Aoki A. Low-Level Erbium-Doped Yttrium Aluminum Garnet Laser Irradiation Induced Alteration of Gene Expression in Osteogenic Cells from Rat Calvariae Photobiomodulation, Photobiomedicine, and Laser Surgery. 2021.07; ( DOI )

  13. Hatasa M, Ohsugi Y, Katagiri S, Yoshida S, Niimi H, Morita K, Tsuchiya Y, Shimohira T, Sasaki N, Maekawa S, Shiba T, Hirota T, Tohara H, Takahashi H, Nitta H, Iwata T. Endotoxemia by Porphyromonas gingivalis alters endocrine functions in brown adipose tissue Frontiers in Cellular and Infection Microbiology. 2021.01; 19 (10): 580577.

  14. Tsuchiya Y, Hayashi M, Nagamatsu K, Ono T, Kamakura M, Iwata T, Nakashima T. The key royal jelly component 10-hydroxy-2-decenoic acid protects against bone loss by inhibiting NF-kappa B signaling downstream of FFAR4 Journal of biological chemistry, Tokyo Medical and Dental University. 2020.08; 295 (34): 12224-12232. ( PubMed, DOI )

  15. Niimi H, Ohsugi Y, Katagiri S, Watanabe K, Hatasa M, Shimohira T, Tsuchiya Y, Maekawa S, Hirota T, Kadokura H, Yokose S, Iwata T, Aoki A. Effects of Low-Level Er:YAG Laser Irradiation on Proliferation and Calcification of Primary Osteoblast-Like Cells Isolated From Rat Calvaria Frontiers in cell and developmental biology. 2020.06; 6 (459):

  16. Hatasa M, Ohsugi Y, Katagiri S, Yoshida S, Niimi H, Morita K, Tsuchiya Y, Shimohira T, Sasaki N, Maekawa S, Shiba T, Hirota T, Tohara H, Takahashi H, Nitta H, Iwata T.. Endotoxemia by Porphyromonas gingivalis alters endocrine functions in brown adipose tissue Frontiers in Cellular and Infection Microbiology. 2020; 10 580577. ( PubMed, DOI )

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Conference Activities & Talks 【 display / non-display 】

  1. Tsuchiya Yosuke, Ohsugi Yujin, Katagiri Sayaka, Hirota Tomomitsu, Iwata Takanori. マウスにおける咬合性外傷のメカニズムに関するトランスクリプトーム解析(Transcriptome analysis for the mechanisms of occlusal trauma in mice). 日本歯周病学会会誌 2024.12.01

  2. 土谷洋輔. 開咬を呈する慢性歯周炎患者に対し、外傷性咬合のコントロールに努めた一症例. 第14回 関東10大学歯周病学講座・第98回日本臨床歯周病学会関東支部合同研修会 2024.11.24 東京

  3. Tsuchiya Y, Ohsugi Y, Katagiri S, Hirota T, Iwata T. Transcriptome analyisis for the mrchanisms of occlusal Trauma in mice. American Academy of Periodontology, 110th Annual Meeting 2024.11.02 San Diego Convention Center

  4. Tsuchiya Y. Elcidation of Mechanisms Regulating Occlusal Trauma in Mice Through Transcriptome analysis. National Taiwan University - Tokyo Medical and Dental University Periodontology Joint Symposium 2024.09.01 Taipei, Taiwan

  5. Yoshida S, Hatasa M, Ohsugi Y, Tsuchiya Y, Liu A, Niimi H, Morita K, Shimohira T, Sasaki N, Maekawa S, Shiba T, Hirota T, Noritake K, Nitta H, Katagiri S, Iwata T. Porphyromonas gingivalis administration induces obesity, modifies gene expression in the liver and brown adipose tissue in pregnant mice, and causes underweight in fetuses. Europerio 10 2022.06.15 Copenhagen

  6. Shimohira T, Niimi H, Ohsugi Y, Tsuchiya Y, Morita K, Yoshida S, Hatasa M, Shiba T, Kadokura H, Yokose S, Katagiri S, Iwata T, Aoki A. . Low-level Er:YAG laser irradiation induced alteration of gene expression in rat calvarial osteogenic cells. Dental Laser Virtual Scientific Conference 2021 2021.07.16

  7. Er:YAGレーザーによるラット頭蓋骨由来初代培養骨芽細胞様細胞の増殖と石灰化に対する効果. 第32回日本レーザー歯学会総会・学術大会 2020.11.28 誌上開催

  8. Niimi H, Ohsugi Y, Katagiri S, Watanabe K, Hatasa M, Shimohira T, Tsuchiya Y, Maekawa S, Hirota T, Kadokura H, Yokose S, Iwata T, Aoki A. The effects of Er:YAG laser irradiation on primary osteoblast-like cells. AAP 106th Annual Meeting 2020.11.06 Virtual

  9. 土谷洋輔. 骨代謝制御におけるローヤルゼリーの効果とその分子メカニズムの解明. 第61回秋季日本歯周病学会学術大会　 2018.10.25 大阪

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