Published Papers & Misc - MIZUNO Mitsuru

1. Mitsuru Mizuno, Yoshitaka Maeda, Sho Sanami, Takahisa Matsuzaki, Hiroshi Y Yoshikawa, Nobutake Ozeki, Hideyuki Koga, Ichiro Sekiya. Noninvasive total counting of cultured cells using a home-use scanner with a pattern sheet. iScience. 2024.03; 27 (3): 109170. ( PubMed, DOI )

2. Yoshimi Sugahara, Mitsuru Mizuno, Noe Miyashita, Hisako Katano, Ichiro Sekiya. Operator stress factors and cell contamination risks in cell processing facilities: An online survey-based analysis. Regen Ther. 2025.06; 29 397-403. ( PubMed, DOI )

3. Ichiro Sekiya, Hisako Katano, Mitsuru Mizuno, Kentaro Endo, Asuka Asami, Michiko Kajiwara, Naoki Otomo, Hideyuki Koga, Jun Masumoto, Nobutake Ozeki. 3D-MRI analysis of cartilage thickness changes after PRP injection in medial knee osteoarthritis: A preliminary report. PLoS One. 2025.04; 20 (4): e0321067. ( PubMed, DOI )

4. Mitsuru Mizuno, Saeri Kimbara, Hanae Ichise, Natsumi Ishikawa, Yuto Nishihara, Miwako Nishio, Ichiro Sekiya. Cleaning methods for biosafety cabinet to eliminate residual mycoplasmas, viruses, and endotoxins after changeover. Regen Ther. 2025.03; 28 73-80. ( PubMed, DOI )

5. Mitsuru Mizuno, Daisuke Suda, Chima Matsumura, Ichiro Sekiya. Changeover method for biosafety cabinets using ozone gas. PLoS One. 2025.01; 20 (1): e0318006. ( PubMed, DOI )

6. Hisako Katano, Nobutake Ozeki, Mitsuru Mizuno, Kentaro Endo, Hideyuki Koga, Jun Masumoto, Ichiro Sekiya. Femoral cartilage defects initiate from medial meniscus extrusion or tibial cartilage lesions and expand in knee osteoarthritis as revealed by 3D MRI analysis. Sci Rep. 2024.10; 14 (1): 25937. ( PubMed, DOI )

7. Nobutake Ozeki, Hideyuki Koga, Tomomasa Nakamura, Hiroki Katagiri, Yusuke Nakagawa, Takashi Hoshino, Mai Katakura, Masaki Amemiya, Aritoshi Yoshihara, Hisako Katano, Mitsuru Mizuno, Kentaro Endo, Jun Masumoto, Ichiro Sekiya. The association of the medial meniscus covering ratio with knee cartilage thickness at 15 medial compartment subregions as found by three-dimensional analysis using MRI. J Exp Orthop. 2024.07; 11 (3): e70005. ( PubMed, DOI )

8. Nobutake Ozeki, Hideyuki Koga, Tomomasa Nakamura, Hiroki Katagiri, Yusuke Nakagawa, Takashi Hoshino, Mai Katakura, Masaki Amemiya, Aritoshi Yoshihara, Hisako Katano, Mitsuru Mizuno, Kentaro Endo, Jun Masumoto, Ichiro Sekiya. Cartilage thickness in the medial compartment of the knee joint evaluated by MRI three-dimensional analysis correlates with weight-bearing line ratio and joint line convergence angle. J Orthop Sci. 2024.07; ( PubMed, DOI )

9. Mitsuru Mizuno, Kouichirou Yori, Toshikazu Takeuchi, Takaaki Yamamoto, Natsumi Ishikawa, Megumi Kobayashi, Miwako Nishio, Ichiro Sekiya. Evaluation of cleaning methods for change-over after the processing of cell products to avoid cross-contamination risk. Regen Ther. 2024.06; 26 489-495. ( PubMed, DOI )

10. Mitsuru Mizuno, Koki Abe, Takashi Kakimoto, Hisashi Hasebe, Ichiro Sekiya. Decreasing electricity costs of clean room for cell products during non-operation. Regen Ther. 2024.06; 26 1117-1123. ( PubMed, DOI )

11. Ryu Yoshida, Hideyuki Koga, Junpei Matsuda, Tomomasa Nakamura, Kazumasa Miyatake, Hiroki Katagiri, Mai Katakura, Aritoshi Yoshihara, Ryota Seki, Toyohiro Katsumata, Mitsuru Mizuno, Ken Watanabe, Ichiro Sekiya, Kunikazu Tsuji, Yusuke Nakagawa. Presoaking grafts in vancomycin does not impair graft-bone healing in a rat anterior cruciate ligament reconstruction model. Am J Sports Med. 2024.06; 52 (7): 1784-1793. ( PubMed, DOI )

12. Mitsuru Mizuno, Koki Abe, Takashi Kakimoto, Hisashi Hasebe, Naoki Kagi, Ichiro Sekiya. Operator-derived particles and falling bacteria in biosafety cabinets. Regenarative Therapy. 2024.03; 25 264-272. ( PubMed, DOI, ichushi )

13. Mitsuru Mizuno, Koki Abe, Takashi Kakimoto, Keiichi Yano, Yukiko Ota, Kengo Tomita, Naoki Kagi, Ichiro Sekiya. Volatile organic compounds and ionic substances contamination in cell processing facilities during rest period; a preliminary assessment of exposure to cell processing operators. Regen Ther. 2023.12; 24 211-218. ( PubMed, DOI )

14. Hisako Katano, Nobutake Ozeki, Mitsuru Mizuno, Kentaro Endo, Noriya Okanouchi 1,2, Jo Fujita, Jun Masumoto, Hideyuki Koga, Ichiro Sekiya. Morphological analysis of three-dimensional MR images of patellofemoral joints in asymptomatic subjects Sci Rep. 2023.12;

15. Mizuno M, Matsuda J, Watanabe K, Shimizu N, Sekiya I. Effect of disinfectants and manual wiping for processing the cell product changeover in a biosafety cabinet. Regenerative therapy. 2023.03; 22 169-175. ( PubMed, DOI )

16. Ozeki N, Mizuno M, Yanada S, Okada T, Kubota R, Kushida Y, Furuoka H, Endo K, Katano H, Nakamura K, Ohya S, Koga H, Sekiya I. Autologous Synovial Mesenchymal Stem Cell Transplantation Suppresses Inflammation Caused by Synovial Harvesting and Promotes Healing in a Micro Minipig Repaired Meniscus Model. Transplantation proceedings. 2023.03; 55 (2): 470-480. ( PubMed, DOI )

17. Shunichi Fujii, Kentaro Endo, Nobutake Ozeki, Yuriko Sakamaki, Yuji Kohno, Mitsuru Mizuno, Hisako Katano, Kunikazu Tsuji, Hideyuki Koga, Ichiro Sekiya. Comparison of adhesion of thawed and cultured synovial mesenchymal stem cells to the porcine meniscus and the relevance of cell surface microspike BMC Molecular and Cell Biology. 2022.12; 23 (1): 53. ( PubMed, DOI )

18. Mitsuru Mizuno, Kouichirou Yori, Toshikazu Takeuchi, Tetsuya Yamaguchi, Ken Watanabe, Yasuhiro Tomaru, Norio Shimizu, Ichiro Sekiya. Cross-contamination risk and decontamination during changeover after cell-product processing. Regenerative Therapy. 2022.12; 22 30-38. ( PubMed, DOI )

19. Mitsuru Mizuno, Yoshimi Sugahara, Daisuke Iwayama, Noe Miyashita, Hisako Katano, Ichiro Sekiya. Stress and motivation of cell processing operators: A pilot study of an online questionnaire survey. Regenerative Therapy. 2022.11; 21 547-552. ( PubMed, DOI )

20. Takahiro Tanimoto, Kentaro Endo, Yuriko Sakamaki, Nobutake Ozeki, Hisako Katanom, Mitsuru Mizuno, Hideyuki Koga, Ichiro Sekiya .. Human synovial mesenchymal stem cells show time-dependent morphological changes and increased adhesion to degenerated porcine cartilage. Scientific Reports. 2022.10; 12 (1): 16619. ( PubMed, DOI )

21. Mituru Mizuno, Nobutake Ozeki, Ichiro Sekiya. Safety of using cultured cells with trisomy 7 in cell therapy for treating osteoarthritis. Regenerative Therapy. 2022.06; 17 (21): 81-86. ( PubMed, DOI )

22. Mituru Mizuno,Takahisa Matsuzaki, Nobutake Ozeki, Hisako Katano, Hideyuki Koga, Takanori Takebe, Hiroshi Yoshikawa, Ichiro Sekiya. Cell membrane fluidity and ROS resistance define DMSO tolerance of cryopreserved synovial MSCs and HUVECs. Stem Cell Research & Therapy. 2022.05; 13 (1): 177. ( PubMed, DOI )

23. Sekiya I, Koga H, Katano H, Mizuno M, Kohno Y, Otabe K, Ozeki N. . Second-look arthroscopy after meniscus repair and synovial mesenchymal stem cell transplantation to treat degenerative flaps and radial tears of the medial meniscus: J Orthop Sci. 2022.05; 27 (4): 821-834. ( PubMed, DOI )

24. Yuji Kohno, Hideyuki Koga, Nobutake Ozeki, Junpei Matsuda, Mitsuru Mizuno, Hisako Katano, Ichiro Sekiya. Biomechanical analysis of a centralization procedure for extruded lateral meniscus after meniscectomy in porcine knee joints. Journal Orthopaedic Research. 2022.05; 40 (5): 1097-1103. ( PubMed, DOI )

25. Yuji Kohno, Mitsuru Mizuno, Kentaro Endo, Nobutake Ozeki, Hisako Katano, Mikio Matsumoto, Haruka Kaneko, Yuji Takazawa, Hideyuki Koga, Ichiro Sekiya. Yields of mesenchymal stromal cells from synovial fluid reflect those from synovium in patients with rheumatoid arthritis Tissue and Cell. 2022.04; 75 101727. ( PubMed, DOI )

26. Mitsuru Mizuno, Kentaro Endo, Hisako Katano, Naoki Amano, Masaki Nomura, Yoshinori Hasegawa, Nobutake Ozeki, Hideyuki Koga, Naoko Takasu, Osamu Ohara, Tomohiro Morio, Ichiro Sekiya. Transplantation of human autologous synovial mesenchymal stem cells with trisomy 7 into the knee joint and 5 years of follow-up. Stem Cells Transl Med. 2021.11; 10 (11): 1530-1543. ( PubMed, DOI )

27. Misaki Yagi, Mitsuru Mizuno, Ryota Fujisawa, Hisako Katano, Kentaro Endo, Nobutake Ozeki, Yuriko Sakamaki, Hideyuki Koga, Ichiro Sekiya. Optimal Pore Size of Honeycomb Polylactic Acid Films for In Vitro Cartilage Formation by Synovial Mesenchymal Stem Cells. Stem Cells Int. 2021.08; 2021 9239728. ( PubMed, DOI )

28. Ichiro Sekiya, Hisako Katano, Mitsuru Mizuno, Hideyuki Koga, Jun Masumoto, Makoto Tomita, Nobutake Ozeki. Alterations in cartilage quantification before and after injections of mesenchymal stem cells into osteoarthritic knees. Sci Rep. 2021.07; 11 (1): 13832. ( PubMed, DOI )

29. Nobutake Ozeki, Yusuke Nakagawa, Mitsuru Mizuno, Yuji Kohno, Hisako Katano, Hideyuki Koga, Ichiro Sekiya. Ultrasound-Guided Harvesting of Synovium for Regenerative Medicine of Cartilage and Meniscus Using Synovial Mesenchymal Stem Cells. Arthrosc Tech. 2021.07; 10 (7): e1723-e1727. ( PubMed, DOI )

30. Kiyotaka Horiuchi, Nobutake Ozeki, Kentaro Endo, Mitsuru Mizuno, Hisako Katano, Masako Akiyama, Kunikazu Tsuji, Hideyuki Koga, Ichiro Sekiya. Thawed cryopreserved synovial mesenchymal stem cells show comparable effects to cultured cells in the inhibition of osteoarthritis progression in rats. Sci Rep. 2021.05; 11 (1): 9683. ( PubMed, DOI )

31. Ozeki Nobutake, Kohno Yuji, Kushida Yoshihisa, Watanabe Naoto, Mizuno Mitsuru, Katano Hisako, Masumoto Jun, Koga Hideyuki, Sekiya Ichiro. Synovial mesenchymal stem cells promote the meniscus repair in a novel pig meniscus injury model JOURNAL OF ORTHOPAEDIC RESEARCH. 2021.01; 39 (1): 177-183. ( PubMed, DOI )

32. Horiuchi Kiyotaka, Mizuno Mitsuru, Katano Hisako, Endo Kentaro, Ozeki Nobutake, Tsuji Kunikazu, Koga Hideyuki, Sekiya Ichiro.. Optimal initial cell density that yields the highest number of primary synovial mesenchymal stem cells in a clinical setting. J Med Dent Sci.. 2021.01; 68 17-26. ( DOI )

33. Yoshihisa Kushida, Nobutake Ozeki, Mitsuru Mizuno, Hisako Katano, Koji Otabe, Kunikazu Tsuji, Hideyuki Koga, Koichiro Kishima, Yoshio Soma, Ichiro Sekiya. Two- and three-dimensional optical coherence tomography to differentiate degenerative changes in a rat meniscectomy model. J Orthop Res. 2020.12; 38 (12): 2592-2600. ( PubMed, DOI )

34. Watanabe Naoto, Endo Kentaro, Komori Keiichiro, Ozeki Nobutake, Mizuno Mitsuru, Katano Hisako, Kohno Yuji, Tsuji Kunikazu, Koga Hideyuki, Sekiya Ichiro. Mesenchymal Stem Cells in Synovial Fluid Increase in Knees with Degenerative Meniscus Injury after Arthroscopic Procedures through the Endogenous Effects of CGRP and HGF. STEM CELL REVIEWS AND REPORTS. 2020.12; 16 (6): 1305-1315. ( PubMed, DOI )

35. Mizuno M, Endo K, Katano H, Tsuji A, Kojima N, Watanabe K, Shimizu N, Morio T, Sekiya I. The environmental risk assessment of cell-processing facilities for cell therapy in a Japanese academic institution. PloS one. 2020.08; 15 (8): e0236600. ( PubMed, DOI )

36. So Suzuki, Mitsuru Mizuno, Yuriko Sakamaki, Ayako Mimata, Kentaro Endo, Yuji Kohno, Nobutake Ozeki, Koji Otabe, Hisako Katano, Kunikazu Tsuji, Hideyuki Koga, Ichiro Sekiya. Morphological changes in synovial mesenchymal stem cells during their adhesion to the meniscus. Lab. Invest.. 2020.07; 100 (7): 916-927. ( PubMed, DOI )

37. Rei Kubota, Hideyuki Koga, Nobutake Ozeki, Junpei Matsuda, Yuji Kohno, Mitsuru Mizuno, Hisako Katano, Ichiro Sekiya. The effect of a centralization procedure for extruded lateral meniscus on load distribution in porcine knee joints at different flexion angles. BMC Musculoskelet Disord. 2020.04; 21 (1): 205. ( PubMed, DOI )

38. Nobutake Ozeki, Hideyuki Koga, Junpei Matsuda, Yuji Kohno, Mitsuru Mizuno, Hisako Katano, Kunikazu Tsuji, Tomoyuki Saito, Takeshi Muneta, Ichiro Sekiya. Biomechanical analysis of the centralization procedure for extruded lateral menisci with posterior root deficiency in a porcine model. J Orthop Sci.. 2020.01; 25 (1): 161-166. ( PubMed, DOI )

39. Mitsuru Mizuno, Hisako Katano, Yuri Shimozaki, Sho Sanami, Nobutake Ozeki, Hideyuki Koga, Ichiro Sekiya. Time-lapse image analysis for whole colony growth curves and daily distribution of the cell number per colony during the expansion of mesenchymal stem cells. Sci Rep. 2019.11; 9 (1): 16835. ( PubMed, DOI )

40. Ichiro Sekiya, Hideyuki Koga, Koji Otabe, Yusuke Nakagawa, Hisako Katano, Nobutake Ozeki, Mitsuru Mizuno, Masafumi Horie, Yuji Kohno, Kenta Katagiri, Naoto Watanabe, Takeshi Muneta. Additional Use of Synovial Mesenchymal Stem Cell Transplantation Following Surgical Repair of a Complex Degenerative Tear of the Medial Meniscus of the Knee: A Case Report. Cell Transplant. 2019.11; 28 (11): 1445-1454. ( PubMed, DOI )

41. Naoto Watanabe, Mitsuru Mizuno, Junpei Matsuda, Naoko Nakamura, Koji Otabe, Hisako Katano, Nobutake Ozeki, Yuji Kohno, Tsuyoshi Kimura, Kunikazu Tsuji, Hideyuki Koga, Akio Kishida, Ichiro Sekiya. Comparison of High-Hydrostatic-Pressure Decellularized Versus Freeze-Thawed Porcine Menisci. J. Orthop. Res.. 2019.11; 37 (11): 2466-2475. ( PubMed, DOI )

42. Akinobu Hyodo, Nobutake Ozeki, Yuji Kohno, So Suzuki, Mitsuru Mizuno, Koji Otabe, Hisako Katano, Makoto Tomita, Yusuke Nakagawa, Hideyuki Koga, Shinji Kiuchi, Kenji Suzuki, Yoshinori Itai, Jun Masumoto, Ichiro Sekiya. Projected Cartilage Area Ratio Determined by 3-Dimensional MRI Analysis: Validation of a Novel Technique to Evaluate Articular Cartilage. JB JS Open Access. 2019.10; 4 (4): e0010. ( PubMed, DOI )

43. Shimpei Kondo, Yusuke Nakagawa, Mitsuru Mizuno, Kenta Katagiri, Kunikazu Tsuji, Shinji Kiuchi, Hideo Ono, Takeshi Muneta, Hideyuki Koga, Ichiro Sekiya. Transplantation of Aggregates of Autologous Synovial Mesenchymal Stem Cells for Treatment of Cartilage Defects in the Femoral Condyle and the Femoral Groove in Microminipigs. Am J Sports Med. 2019.08; 47 (10): 2338-2347. ( PubMed, DOI )

44. Ryota Fujisawa, Mitsuru Mizuno, Hisako Katano, Koji Otabe, Nobutake Ozeki, Kunikazu Tsuji, Hideyuki Koga, Ichiro Sekiya. Cryopreservation in 95% serum with 5% DMSO maintains colony formation and chondrogenic abilities in human synovial mesenchymal stem cells. BMC Musculoskelet Disord. 2019.07; 20 (1): 316. ( PubMed, DOI )

45. Kaori Nakamura, Kunikazu Tsuji, Mitsuru Mizuno, Hideyuki Koga, Takeshi Muneta, Ichiro Sekiya. Initial cell plating density affects properties of human primary synovial mesenchymal stem cells. J. Orthop. Res.. 2019.06; 37 (6): 1358-1367.

46. Naritomi M, Mizuno M, Katano H, Ozeki N, Otabe K, Komori K, Fujii S, Ichinose S, Tsuji K, Koga H, Muneta T, Sekiya I. Petaloid recombinant peptide enhances in vitro cartilage formation by synovial mesenchymal stem cells. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2019.06; 37 (6): 1350-1357. ( PubMed, DOI )

47. Nakamura Kaori, Tsuji Kunikazu, Mizuno Mitsuru, Koga Hideyuki, Muneta Takeshi, Sekiya Ichiro. Initial cell plating density affects properties of human primary synovial mesenchymal stem cells JOURNAL OF ORTHOPAEDIC RESEARCH. 2019.06; 37 (6): 1358-1367. ( DOI )

48. Akari Sasaki, Mitsuru Mizuno, Manabu Mochizuki, Ichiro Sekiya. Mesenchymal stem cells for cartilage regeneration in dogs. World J Stem Cells. 2019.05; 11 (5): 254-269. ( PubMed, DOI )

49. Akari Sasaki, Mitsuru Mizuno, Nobutake Ozeki, Hisako Katano, Koji Otabe, Kunikazu Tsuji, Hideyuki Koga, Manabu Mochizuki, Ichiro Sekiya. Canine mesenchymal stem cells from synovium have a higher chondrogenic potential than those from infrapatellar fat pad, adipose tissue, and bone marrow. PLoS ONE. 2018.08; 13 (8): e0202922. ( PubMed, DOI )

50. Katano H, Koga H, Ozeki N, Otabe K, Mizuno M, Tomita M, Muneta T, Sekiya I.. Trends in isolated meniscus repair and meniscectomy in Japan, 2011-2016. PLoS ONE. 2018.07; 23 (4): 676-681. ( PubMed, DOI )

51. Ogata Yusuke, Mabuchi Yo, Shinoda Kosuke, Horiike Yuta, Mizuno Mitsuru, Otabe Koji, Suto Eriko Grace, Suzuki Nobuharu, Sekiya Ichiro, Akazawa Chihiro. Anterior cruciate ligament-derived mesenchymal stromal cells have a propensity to differentiate into the ligament lineage Regenerative Therapy. 2018.06; 8 20-28. ( DOI )

52. Ogata Yusuke, Mabuchi Yo, Shinoda Kosuke, Horiike Yuta, Mizuno Mitsuru, Otabe Koji, Suto Eriko Grace, Suzuki Nobuharu, Sekiya Ichiro, Akazawa Chihiro. Anterior cruciate ligament-derived mesenchymal stromal cells have a propensity to differentiate into the ligament lineage(和訳中) Regenerative Therapy. 2018.06; 8 20-28. ( ichushi )

53. Mitsuru Mizuno, Hisako Katano, Yo Mabuchi, Yusuke Ogata, Shizuko Ichinose, Shizuka Fujii, Koji Otabe, Keiichiro Komori, Nobutake Ozeki, Hideyuki Koga, Kunikazu Tsuji, Chihiro Akazawa, Takeshi Muneta, Ichiro Sekiya. Specific markers and properties of synovial mesenchymal stem cells in the surface, stromal, and perivascular regions. Stem Cell Research & Therapy. 2018.05; 9 (1): 123. ( PubMed, DOI )

54. Sekiya Ichiro, Koga Hideyuki, Otabe Koji, Nakagawa Yusuke, Katano Hisako, Ozeki Nobutake, Mizuno Mitsuru, Horie Masafumi, Muneta Takeshi. Regenerative medicine in Knee 変性半月板断裂に対する修復+滑膜幹細胞移植の2年成績(Regenerative medicine in Knee Transplantation of synovial stem cells onto degenerative torn meniscus: a 2-year follow-up study) JOSKAS. 2018.05; 43 (4): 171. ( ichushi )

55. Ken Watanabe, Koji Otabe, Norio Shimizu, Keiichirou Komori, Mitsuru Mizuno, Hisako Katano, Hideyuki Koga, Ichiro Sekiya. High-sensitivity virus and mycoplasma screening test reveals high prevalence of parvovirus B19 infection in human synovial tissues and bone marrow. Stem Cell Res Ther. 2018.03; 9 (1): 80. ( PubMed, DOI )

56. Yuji Kohno, Mitsuru Mizuno, Nobutake Ozeki, Hisako Katano, Koji Otabe, Hideyuki Koga, Mikio Matsumoto, Haruka Kaneko, Yuji Takazawa, Ichiro Sekiya. Comparison of mesenchymal stem cells obtained by suspended culture of synovium from patients with rheumatoid arthritis and osteoarthritis. BMC Musculoskelet Disord. 2018.03; 19 (1): 78. ( PubMed, DOI )

57. Kondo S, Muneta T, Nakagawa Y, Koga H, Watanabe T, Tsuji K, Sotome S, Okawa A, Kiuchi S, Ono H, Mizuno M, Sekiya I.. Transplantation of Autologous Synovial Mesenchymal Stem Cells Promotes Meniscus Regeneration in Aged Primates Journal of Orthopaedic Research. 2017.06; 35 (6): 1274-1282. ( PubMed, DOI )

58. Mitsuru Mizuno, Hisako Katano, Koji Otabe, Keiichiro Komori, Yuji Kohno, Shizuka Fujii, Nobutake Ozeki, Masafumi Horie, Kunikazu Tsuji, Hideyuki Koga, Takeshi Muneta, Ichiro Sekiya. Complete human serum maintains viability and chondrogenic potential of human synovial stem cells: suitable conditions for transplantation. Stem Cell Research & Therapy. 2017.06; 8 (1): 144. ( PubMed, DOI )

59. Yuji Kohno, Mitsuru Mizuno, Nobutake Ozeki, Hisako Katano, Keiichiro Komori, Shizuka Fujii, Koji Otabe, Masafumi Horie, Hideyuki Koga, Kunikazu Tsuji, Mikio Matsumoto, Haruka Kaneko, Yuji Takazawa, Takeshi Muneta, Ichiro Sekiya. Yields and chondrogenic potential of primary synovial mesenchymal stem cells are comparable between rheumatoid arthritis and osteoarthritis patients. Stem Cell Res Ther. 2017.05; 8 (1): 115. ( PubMed, DOI )

60. Mikio Shioda, Takeshi Muneta, Kunikazu Tsuji, Mitsuru Mizuno, Keiichiro Komori, Hideyuki Koga, Ichiro Sekiya. TNFα promotes proliferation of human synovial MSCs while maintaining chondrogenic potential. PLoS ONE. 2017.05; 12 (5): e0177771. ( PubMed, DOI )

61. Katagiri Kenta, Yu Matsukura, Takeshi Muneta, Nobutake Ozeki, Mitsuru Mizuno, Hisako Katano, Ichiro Sekiya.. Fibrous synovium releases higher numbers of mesenchymal stem cells than adipose synovium in a suspended synovium culture model. Arthroscopy. 2017.04; 33 (4): 800-810. ( PubMed )