Published Papers & Misc - MIZUNO Mitsuru

1. Mitsuru Mizuno, Yoshitaka Maeda, Sho Sanami, Takahisa Matsuzaki, Hiroshi Y Yoshikawa, Nobutake Ozeki, Hideyuki Koga, Ichiro Sekiya. Noninvasive total counting of cultured cells using a home-use scanner with a pattern sheet. iScience. 2024.03; 27 (3): 109170. ( PubMed, DOI )

2. Yoshimi Sugahara, Mitsuru Mizuno, Noe Miyashita, Hisako Katano, Ichiro Sekiya. Operator stress factors and cell contamination risks in cell processing facilities: An online survey-based analysis. Regen Ther. 2025.06; 29 397-403. ( PubMed, DOI )

3. Ichiro Sekiya, Hisako Katano, Mitsuru Mizuno, Kentaro Endo, Asuka Asami, Michiko Kajiwara, Naoki Otomo, Hideyuki Koga, Jun Masumoto, Nobutake Ozeki. 3D-MRI analysis of cartilage thickness changes after PRP injection in medial knee osteoarthritis: A preliminary report. PLoS One. 2025.04; 20 (4): e0321067. ( PubMed, DOI )

4. Mitsuru Mizuno, Saeri Kimbara, Hanae Ichise, Natsumi Ishikawa, Yuto Nishihara, Miwako Nishio, Ichiro Sekiya. Cleaning methods for biosafety cabinet to eliminate residual mycoplasmas, viruses, and endotoxins after changeover. Regen Ther. 2025.03; 28 73-80. ( PubMed, DOI )

5. Mitsuru Mizuno, Daisuke Suda, Chima Matsumura, Ichiro Sekiya. Changeover method for biosafety cabinets using ozone gas. PLoS One. 2025.01; 20 (1): e0318006. ( PubMed, DOI )

6. Hisako Katano, Nobutake Ozeki, Mitsuru Mizuno, Kentaro Endo, Hideyuki Koga, Jun Masumoto, Ichiro Sekiya. Femoral cartilage defects initiate from medial meniscus extrusion or tibial cartilage lesions and expand in knee osteoarthritis as revealed by 3D MRI analysis. Sci Rep. 2024.10; 14 (1): 25937. ( PubMed, DOI )

7. Nobutake Ozeki, Hideyuki Koga, Tomomasa Nakamura, Hiroki Katagiri, Yusuke Nakagawa, Takashi Hoshino, Mai Katakura, Masaki Amemiya, Aritoshi Yoshihara, Hisako Katano, Mitsuru Mizuno, Kentaro Endo, Jun Masumoto, Ichiro Sekiya. The association of the medial meniscus covering ratio with knee cartilage thickness at 15 medial compartment subregions as found by three-dimensional analysis using MRI. J Exp Orthop. 2024.07; 11 (3): e70005. ( PubMed, DOI )

8. Nobutake Ozeki, Hideyuki Koga, Tomomasa Nakamura, Hiroki Katagiri, Yusuke Nakagawa, Takashi Hoshino, Mai Katakura, Masaki Amemiya, Aritoshi Yoshihara, Hisako Katano, Mitsuru Mizuno, Kentaro Endo, Jun Masumoto, Ichiro Sekiya. Cartilage thickness in the medial compartment of the knee joint evaluated by MRI three-dimensional analysis correlates with weight-bearing line ratio and joint line convergence angle. J Orthop Sci. 2024.07; ( PubMed, DOI )

9. Mitsuru Mizuno, Kouichirou Yori, Toshikazu Takeuchi, Takaaki Yamamoto, Natsumi Ishikawa, Megumi Kobayashi, Miwako Nishio, Ichiro Sekiya. Evaluation of cleaning methods for change-over after the processing of cell products to avoid cross-contamination risk. Regen Ther. 2024.06; 26 489-495. ( PubMed, DOI )

10. Mitsuru Mizuno, Koki Abe, Takashi Kakimoto, Hisashi Hasebe, Ichiro Sekiya. Decreasing electricity costs of clean room for cell products during non-operation. Regen Ther. 2024.06; 26 1117-1123. ( PubMed, DOI )

11. Ryu Yoshida, Hideyuki Koga, Junpei Matsuda, Tomomasa Nakamura, Kazumasa Miyatake, Hiroki Katagiri, Mai Katakura, Aritoshi Yoshihara, Ryota Seki, Toyohiro Katsumata, Mitsuru Mizuno, Ken Watanabe, Ichiro Sekiya, Kunikazu Tsuji, Yusuke Nakagawa. Presoaking grafts in vancomycin does not impair graft-bone healing in a rat anterior cruciate ligament reconstruction model. Am J Sports Med. 2024.06; 52 (7): 1784-1793. ( PubMed, DOI )

12. Mitsuru Mizuno, Koki Abe, Takashi Kakimoto, Hisashi Hasebe, Naoki Kagi, Ichiro Sekiya. Operator-derived particles and falling bacteria in biosafety cabinets. Regenarative Therapy. 2024.03; 25 264-272. ( PubMed, DOI, ichushi )

13. Mitsuru Mizuno, Koki Abe, Takashi Kakimoto, Keiichi Yano, Yukiko Ota, Kengo Tomita, Naoki Kagi, Ichiro Sekiya. Volatile organic compounds and ionic substances contamination in cell processing facilities during rest period; a preliminary assessment of exposure to cell processing operators. Regen Ther. 2023.12; 24 211-218. ( PubMed, DOI )

14. Hisako Katano, Nobutake Ozeki, Mitsuru Mizuno, Kentaro Endo, Noriya Okanouchi 1,2, Jo Fujita, Jun Masumoto, Hideyuki Koga, Ichiro Sekiya. Morphological analysis of three-dimensional MR images of patellofemoral joints in asymptomatic subjects Sci Rep. 2023.12;

15. Mizuno M, Matsuda J, Watanabe K, Shimizu N, Sekiya I. Effect of disinfectants and manual wiping for processing the cell product changeover in a biosafety cabinet. Regenerative therapy. 2023.03; 22 169-175. ( PubMed, DOI )

16. Ozeki N, Mizuno M, Yanada S, Okada T, Kubota R, Kushida Y, Furuoka H, Endo K, Katano H, Nakamura K, Ohya S, Koga H, Sekiya I. Autologous Synovial Mesenchymal Stem Cell Transplantation Suppresses Inflammation Caused by Synovial Harvesting and Promotes Healing in a Micro Minipig Repaired Meniscus Model. Transplantation proceedings. 2023.03; 55 (2): 470-480. ( PubMed, DOI )

17. Mitsuru Mizuno, Kouichirou Yori, Toshikazu Takeuchi, Tetsuya Yamaguchi, Ken Watanabe, Yasuhiro Tomaru, Norio Shimizu, Ichiro Sekiya. Cross-contamination risk and decontamination during changeover after cell-product processing. Regenerative Therapy. 2022.12; 22 30-38. ( PubMed, DOI )

18. Shunichi Fujii, Kentaro Endo, Nobutake Ozeki, Yuriko Sakamaki, Yuji Kohno, Mitsuru Mizuno, Hisako Katano, Kunikazu Tsuji, Hideyuki Koga, Ichiro Sekiya. Comparison of adhesion of thawed and cultured synovial mesenchymal stem cells to the porcine meniscus and the relevance of cell surface microspike BMC Molecular and Cell Biology. 2022.12; 23 (1): 53. ( PubMed, DOI )

19. Mitsuru Mizuno, Yoshimi Sugahara, Daisuke Iwayama, Noe Miyashita, Hisako Katano, Ichiro Sekiya. Stress and motivation of cell processing operators: A pilot study of an online questionnaire survey. Regenerative Therapy. 2022.11; 21 547-552. ( PubMed, DOI )

20. Takahiro Tanimoto, Kentaro Endo, Yuriko Sakamaki, Nobutake Ozeki, Hisako Katanom, Mitsuru Mizuno, Hideyuki Koga, Ichiro Sekiya .. Human synovial mesenchymal stem cells show time-dependent morphological changes and increased adhesion to degenerated porcine cartilage. Scientific Reports. 2022.10; 12 (1): 16619. ( PubMed, DOI )