Graduating School 【 display / non-display 】
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Tokyo Medical and Dental University, Faculty of Medicine, 2009.03, Graduated
Graduate School 【 display / non-display 】
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Tokyo Medical and Dental University, Graduate School, Division of Medical Sciences, Doctor's Course, 2019.09, Completed
Campus Career 【 display / non-display 】
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2009.04-2010.03Tokyo Medical and Dental University, (Old Organization)Medical Hospital, Trainee Resident
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2012.04-2013.03Tokyo Medical and Dental University, (Old Organization)Medical Hospital, Senior Resident
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2014.04-2015.03Tokyo Medical and Dental University, (Old Organization)Medical Hospital, Senior Resident
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2015.04-2019.09Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Environmental Response, Rheumatology, Graduate Student
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2019.04-2019.09Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Environmental Response, Rheumatology, Graduate Student
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2019.04-2021.03Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Environmental Response, Rheumatology, Project Assistant Professor
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2019.11-2021.03Tokyo Medical and Dental University, (Old Organization)Medical Hospital, Hospital Departments, Department of Internal Medicine, Rheumatology, Project Assistant Professor
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2021.04-2021.09Tokyo Medical and Dental University, (Old Organization)Medical Hospital, Hospital Departments, Department of Internal Medicine, Rheumatology, Assistant Professor
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2021.04-NowTokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Environmental Response, Rheumatology, Assistant Professor
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2021.10-NowTokyo Medical and Dental University, Tokyo Medical and Dental University, Division of Clinical Medicine, Department of Internal Medicine, Rheumatology, Assistant Professor
External Career 【 display / non-display 】
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2010.04-2011.03, Trainee Resident
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2011.04-2012.03, Senior Resident
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2013.04-2014.03, Senior Resident
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2023.04-NowBrigham and Women's Hospital, Pulmonary and Critical Care Medicine, Postdoctoral Research Fellow
Published Papers & Misc 【 display / non-display 】
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Mari Kamiya, Fumitaka Mizoguchi, Kimito Kawahata, Dengli Wang, Masahiro Nishibori, Jessica Day, Cynthia Louis, Ian P Wicks, Hitoshi Kohsaka, Shinsuke Yasuda. Targeting necroptosis in muscle fibers ameliorates inflammatory myopathies Nature Communications. 2022.01; 13 (1): 166. ( PubMed, DOI )
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Nguyen HN, Jeong Y, Kim Y, Kamiya M, Kim Y, Athar H, Castaldi PJ, Hersh CP, Menon JA, Wong J, Chan I, Oldham WM, Padera RF, Sharma NS, Sholl LM, Vivero M, Watts GFM, Knipe RS, Black KE, Hariri LP, Yun JH, Merriam LT, Yuan K, Kim EY, Brenner MB.. Leukemia inhibitory factor (LIF) receptor amplifies pathogenic activation of fibroblasts in lung fibrosis Proc Natl Acad Sci U S A. 2024.12; 121 (50): e2401899121. ( PubMed, DOI )
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Komiya Y, Kamiya M, Oba S, Kawata D, Iwai H, Shintaku H, Suzuki Y, Miyamoto S, Tobiume M, Kanno T, Ainai A, Suzuki T, Hasegawa H, Hosoya T, Yasuda S. Necroptosis in alveolar epithelial cells drives lung inflammation and injury caused by SARS-CoV-2 infection. Biochimica et biophysica acta. Molecular basis of disease. 2024.08; 1870 (8): 167472. ( PubMed, DOI )
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Mari Kamiya, Hannah Carter, Milena S Espindola, Tracy J Doyle, Joyce S Lee, Louis T Merriam, Fan Zhang, Leticia Kawano-Dourado, Jeffrey A Sparks, Cory M Hogaboam, Bethany B Moore, William M Oldham, Edy Y Kim. Immune mechanisms in fibrotic interstitial lung disease. Cell. 2024.07; 187 (14): 3506-3530. ( PubMed, DOI )
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Takumi Matsumoto, Takahiko Sugihara, Tadashi Hosoya, Tatsuro Ishizaki, Kanae Kubo, Mari Kamiya, Hiroyuki Baba, Marina Tsuchida, Fumio Hirano, Masayo Kojima, Nobuyuki Miyasaka, Masayoshi Harigai. Effectiveness and safety of treat-to-target strategy for methotrexate-naïve rheumatoid arthritis patients >75 years of age Rheumatology Advances in Practice. 2024.02; 8 (1): rkae019. ( PubMed, DOI )
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Komiya Yoji, Sugihara Takahiko, Hirano Fumio, Matsumoto Takumi, Kamiya Mari, Sasaki Hirokazu, Hosoya Tadashi, Kimura Naoki, Ishizaki Tatsuro, Mori Masaaki, Tohma Shigeto, Yasuda Shinsuke, Matsui Toshihiro. 低疾患活動性を達成した高齢関節リウマチ患者における身体機能低下関連因子(Factors associated with impaired physical function in elderly rheumatoid arthritis patients who had achieved low disease activity) Modern Rheumatology. 2024.01; 34 (1): 60-67. ( ichushi )
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Ana B Villaseñor-Altamirano, Dhawal Jain, Yunju Jeong, Jaivardhan A Menon, Mari Kamiya, Hibah Haider, Reshmi Manandhar, Muhammad Dawood Amir Sheikh, Humra Athar, Louis T Merriam, Min Hyung Ryu, Takanori Sasaki, Peter J Castaldi, Deepak A Rao, Lynette M Sholl, Marina Vivero, Craig P Hersh, Xiaobo Zhou, Justus Veerkamp, Jeong H Yun, Edy Y Kim; MGB-Bayer Pulmonary Drug Discovery Lab. Activation of CD8+ T Cells in COPD Lung Am J Respir Crit Care Med. 2023.10; ( DOI )
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Mari Kamiya, Naoki Kimura, Natsuka Umezawa, Hisanori Hasegawa and Shinsuke Yasuda. Muscle fiber necroptosis in pathophysiology of idiopathic inflammatory myopathies and its potential as target of novel treatment strategy Frontiers in Immunology. 2023.07; 14 1191815. ( DOI )
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Hosoya T, Oba S, Komiya Y, Kawata D, Kamiya M, Iwai H, Miyamoto S, Kataoka M, Tobiume M, Kanno T, Ainai A, Sato H, Hirakawa A, Mitsui Y, Satoh T, Wakabayashi K, Yamada T, Otomo Y, Miyazaki Y, Hasegawa H, Suzuki T, Yasuda S. Apple-shaped obesity: A risky soil for cytokine-accelerated severity in COVID-19. Proceedings of the National Academy of Sciences of the United States of America. 2023.05; 120 (22): e2300155120. ( PubMed, DOI )
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Komiya Y, Sugihara T, Hirano F, Matsumoto T, Kamiya M, Sasaki H, Hosoya T, Kimura N, Ishizaki T, Mori M, Tohma S, Yasuda S, Matsui T. Factors associated with impaired physical function in elderly rheumatoid arthritis patients who had achieved low disease activity. Modern rheumatology. 2022.12; ( PubMed, DOI )
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Mari Kamiya,Fumitaka Mizoguchi,Shinsuke Yasuda. Amelioration of inflammatory myopathies by glucagon-like peptide-1 receptor agonist via suppressing muscle fibre necroptosis Journal of Cachexia, Sarcopenia and Muscle. 2022.06; 13 (4): 2118-2131. ( PubMed, DOI )
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Yoshizuka R, Hasegawa H, Kamiya M, Umezawa N, Yasuda S. Refractory antiphospholipid antibody syndrome-induced thrombocytopaenia successfully treated with belimumab. Lupus. 2022.04; 31 (5): 624-627. ( PubMed, DOI )
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Sugihara T, Ishizaki T, Onoguchi W, Baba H, Matsumoto T, Iga S, Kubo K, Kamiya M, Hirano F, Hosoya T, Miyasaka N, Harigai M. Effectiveness and safety of treat-to-target strategy in elderly-onset rheumatoid arthritis: a 3-year prospective observational study. Rheumatology (Oxford, England). 2021.01; ( PubMed, DOI )
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Oba S, Hosoya T, Amamiya M, Mitsumura T, Kawata D, Sasaki H, Kamiya M, Yamamoto A, Ando T, Shimada S, Shirai T, Okamoto T, Tateishi T, Endo A, Aiboshi J, Nosaka N, Yamanouchi H, Ugawa T, Nagaoka E, Oi K, Tao S, Maejima Y, Tanaka Y, Tanimoto K, Takeuchi H, Tohda S, Hirakawa A, Sasano T, Arai H, Otomo Y, Miyazaki Y, Yasuda S. Arterial and Venous Thrombosis Complicated in COVID-19: A Retrospective Single Center Analysis in Japan. Frontiers in cardiovascular medicine. 2021; 8 767074. ( PubMed, DOI )
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Kamiya M, Mizoguchi F, Takamura A, Kimura N, Kawahata K, Kohsaka H. A new in vitro model of polymyositis reveals CD8+ T cell invasion into muscle cells and its cytotoxic role. Rheumatology (Oxford, England). 2019.06; ( PubMed, DOI )
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Ota M, Iwai H, Imai K, Kamiya M, Yoshihashi-Nakazato Y, Miyasaka N, Kohsaka H. Acute Tubulointerstitial Nephritis Associated with Infliximab in a Patient with Crohn's Disease Intern Med.. 2016; 55 (10): 1367-1370.
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Mari Kamiya, Peter Y Shane, Makoto Soejima, Shuji Tohda, Nobuyuki Miyasaka, Hitoshi Kohsaka. IgG4-Related Sialoadenitis with a Skin Lesion and Multiple Mononeuropathies Suggesting Coexistent Cryoglobulinemic Vasculitis. Intern. Med.. 2016; 55 (10): 1355-1361. ( PubMed, DOI )
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Tatsuya Kawasaki, Mari Kamiya, Atsushi Nakagawa, Jun Takagiwa, Yutaka Kawahara, Yoshinori Nonomura. Allergic bronchopulmonary aspergillosis in a patient with rheumatoid arthritis under adalimumab therapy: a case report Nihon Rinsho Meneki Gakkai Kaishi. 2016; 39 (1): 84-89. ( PubMed )
Conference Activities & Talks 【 display / non-display 】
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Mari Kamiya, Marina Tsuchida, Hirokazu Sasaki, Natuka Umezawa, Shinsuke Yasuda. Glucagon-like peptide-1 receptor agonist ameliorates inflammatory myopathies via suppressing muscle fiber necroptosis. The 51st Annual Meeting of the Japanese Society for Immunology 2022.12.09 Kumamoto, Japan
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Shinsuke Yasuda, Mari Kamiya, Fumitaka Mizoguchi, Kimito Kawahata, Dengli Wang, Masahiro Nishibori, Jessica Day, Cynthia Louis, Ian P Wicks, Hitoshi Kohsaka . Targeting Necroptosis in Muscle Fibers in Polymyositis. ACR Convergence 2022 2022.11.13 Philadelphia, Pennsylvania, USA
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Mari Kamiya, Fumitaka Mizoguchi, Hirokazu Sasaki, Natsuka Umezawa, Shinsuke Yasuda. Agonistic stimulation of Glucagon-like peptide-1 receptor ameliorated inflammatory myopathies through suppressing muscle fiber necroptosis. EULAR2022 2022.06.02 Bella Center Copenhagen, Copenhagen, Denmark
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Mari Kamiya, Fumitaka Mizoguchi, Shinsuke Yasuda. Agonistic stimulation of Glucagon-like peptide-1 receptor ameliorates experimental polymyositis through inhibiting muscle fiber necroptosis. 66th Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology 2022.04.26 Yokohama, Japan
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Mari Kamiya, Shinsuke Yasuda. Targeting necroptosis in muscle fibers ameliorates experimental inflammatory myopathies. The 50 th Annual Meeting of the Japanese Society for Immunology 2021.12.09 Nara, Japan
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Mari Kamiya, Fumitaka Mizoguchi, Hirokazu Sasaki, Natsuka Umezawa, and Shinsuke Yasuda. Glucagon-like Peptide-1 Receptor Agonist Suppresses Muscle Fiber Necroptosis and Muscle Inflammation and Ameliorates Muscle Weakness in Experimental Polymyositis. ACR Convergence 2021 2021.11.07
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Mari Kamiya, Shinsuke Yasuda, Fumitaka Mizoguchi. HMGB1 is highly expressed in injured muscle fibers and accelerates inflammation and muscle injury in inflammatory myopathies. 65th Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology 2021.04.27
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Mari Kamiya, Seon Uk Kim, Jeong Yeon Kim, Shinsuke Yasuda, Eun Young Lee, Fumitaka Mizoguchi. Glucagon-like Peptide-1 Receptor Agonist Suppresses Muscle Inflammation and Muscle Fiber Death, and Ameliorates Muscle Weakness in Experimental Polymyositis. ACR Convergence 2020 2020.11.09 Online
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Mari Kamiya, Kimito Kawahata, Hitoshi Kohsaka , Fumitaka Mizoguchi. Targeting necroptosis in muscle cells ameliorates inflammatory myopathies. 64th Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology 2020.08.17
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Mari Kamiya, Seon Uk Kim, Jeong Yeon Kim, Yeong Wook Song, Eun Young Lee, Fumitaka Mizoguchi. Glucagon-like peptide-1 receptor agonist ameliorated muscle weakness and inflammation in experimental polymyositis. European Congress of Rheumatology (EULAR) 2020 2020.06.06
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Komiya Yoji, Kamiya Mari, Hosoya Tadashi, Oba Seiya, Kawata Daisuke, Iwai Hideyuki, Miyamoto Sho, Kanno Takayuki, Ainai Akira, Suzuki Tadaki, Hasegawa Hideki, Yasuda Shinsuke. 肺胞上皮細胞におけるFASを介したネクロプトーシスの抑制はCOVID-19マウスモデルにおける肺傷害とその後のインフラマソーム活性化を抑制する(Inhibition of FAS-mediated necroptosis in alveolar epithelial cell suppresses lung injury and subsequent inflammasome activation in murine COVID-19 model). 日本免疫学会総会・学術集会記録 2023.12.01
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Hosoya Tadashi, Oba Seiya, Komiya Yoji, Kawata Daisuke, Kamiya Mari, Iwai Hideyuki, Miyamoto Sho, Kanno Takayuki, Ainai Akira, Suzuki Tadaki, Hasegawa Hideki, Yasuda Shinsuke. Infection and Immunity II(The underlying mechanism of the deterioration in obese patients with COVID-19). 日本免疫学会総会・学術集会記録 2022.11.01
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Mari Kamiya, Kimito Kawahata, Hitoshi Kohsaka, Fumitaka Mizoguchi. Inhibition of Necroptosis Suppresses Muscle Cell Death and Inflammatory Infiltrate, and Improves Muscle Strength in Experimental Polymyositis. 2019 ACR/ARP Annual meeting 2019.11.10 Atlanta, GA, USA
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Mari Kamiya, Fumitaka Mizoguchi, Kimito Kawahata, Hitoshi Kohsaka. Inhibition of necroptosis ameliorates in vitro and in vivo models of polymyositis. 63rd Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology 2019.04.16 Kyoto International Conference Center, Kyoto, Japan
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Sugihara Takahiko, Ishizaki Tatsuro, Baba Hiroyuki, Matsumoto Takumi, Iga Shoko, Kusuda Takeshi, Tsuchida Marina, Kamiya Mari, Komiya Yoji, Hirano Fumio, Hosoya Tadashi, Miyasaka Nobuyuki, Harigai Masayoshi. Three Year Outcomes of Patients with Elderly-Onset Rheumatoid Arthritis Treated with a Therapeutic Strategy Targeting Low Disease Activity, and Impact of Adverse Events on Physical Function. 2018 ACR/ARP Annual meeting 2018.09
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Mari Kamiya, Naoki Kimura, Akito Takamura, Fumitaka Mizoguchi, Kimito Kawahata, Hitoshi Kohsaka. Cytotoxic T lymphocytes induced perforin/granzyme-dependent apoptosis of myoblasts and Fas/FasL-dependent necroptosis of myotubes in in vitro model of myositis.. JCR international School 2018 2018.08.02
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Mari Kamiya, Naoki Kimura, Akito Takamura, Fumitaka Mizoguchi, Kimito Kawahata, Hitoshi Kohsaka. Study of in vitro T cell/myotube interaction disclosed invasive and cytotoxic nature of CD8+ cells enclosed in the muscle cells.. 19th Asia Pacific League of Associations for Rheumatology Congress (APLAR 2017) 2017.10.20 Dubai World Trade Center
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戸倉 雅, 神谷 麻理, 川畑 仁人, 上阪 等. ステロイド抵抗性心筋炎、心膜炎を呈したシェーグレン症候群. 日本内科学会関東地方会 2016.06
Awards & Honors 【 display / non-display 】
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JCR Promotion Award,Japan College of Rheumatology,2023.04
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Excellence in Research Awards,Tokyo Medical and Dental University,2022.10
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JCR2022 ICW Excellent Abstract Award,Japan College of Rheumatology,2022.04
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Excellent Abstract Award, 8th Basic Research Conference,Japan College of Rheumatology,2021.11
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Career development award,The Ichiro Kanehara Foundation for the Promotion of Medical Sciences and Medical Care,2020.09
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ICW Excellent Abstract Award, 66th Annual General Assembly and scientific Meeting of the Japan College of Rheumatology,Japan College of Rheumatology,2019.04
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APLAR2017 Travel Award,Japan College of Rheumatology,2017.10
Others 【 display / non-display 】
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A novel drug suppresses muscle inflammation and restores muscle weakness,2022.08
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Targeting necroptosis for inflammatory myopathies,2022.03
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