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Kobayashi Satoru, Mizuno Nana, Yokoi Kyoko, Mori Takayasu, Sohara Eisei, Uchida Shinichi. Congenital nephrogenic diabetes insipidus presenting as osmotic demyelination syndrome in infancy A case report MEDICINE. 2022.01; 101 (3): e28552. ( PubMed, DOI )

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Morimoto Nobuhisa, Nagahama Kiyotaka, Mori Takayasu, Fujimaru Takuya, Tsuura Yukio, Terai Ayumi, Tanabe Madoka, Otani Megumi, Shioji Shingo, Hirasawa Suguru, Aki Shota, Aoyagi Makoto, Sohara Eisei, Uchida Shinichi, Tanaka Hiroyuki. A Novel LMX1B Variant Identified in a Patient Presenting with Severe Renal Involvement and Thin Glomerular Basement Membrane NEPHRON. 2021.11; 145 (6): 776-782. ( PubMed, DOI )

Mandai Shintaro, Ando Fumiaki, Mori Takayasu, Susa Koichiro, Iimori Soichiro, Naito Shotaro, Sohara Eisei, Uchida Shinichi, Fushimi Kiyohide, Rai Tatemitsu. Burden of kidney disease on the discrepancy between reasons for hospital admission and death: An observational cohort study PLOS ONE. 2021.11; 16 (11): e0258846. ( PubMed, DOI )

Fujii Shinya, Kikuchi Eriko, Suzuyama Honoka, Watanabe Yuko, Ishigami-Yuasa Mari, Masuno Hiroyuki, Mori Takayasu, Isobe Kiyoshi, Uchida Shinichi, Kagechika Hiroyuki. Structural Development of Salicylanilide-Based SPAK Inhibitors as Candidate Antihypertensive Agents CHEMMEDCHEM. 2021.07; 16 (18): 2817-2822. ( PubMed, DOI )

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Nanamatsu Azuma, Mori Takayasu, Ando Fumiaki, Furusho Taisuke, Mandai Shintaro, Susa Koichiro, Sohara Eisei, Rai Tatemitsu, Uchida Shinichi. Vasopressin Induces Urinary Uromodulin Secretion By Activating PKA (Protein Kinase A) HYPERTENSION. 2021.06; 77 (6): 1953-1963. ( PubMed, DOI )

Kandhaya-Pillai Renuka, Hou Deyin, Zhang Jiaming, Yang Xiaomeng, Compoginis Goli, Mori Takayasu, Tchkonia Tamara, Martin George M., Hisama Fuki M., Kirkland James L., Oshima Junko. SMAD4 mutations and cross-talk between TGF-beta/IFN gamma signaling accelerate rates of DNA damage and cellular senescence, resulting in a segmental progeroid syndrome-the Myhre syndrome GEROSCIENCE. 2021.06; 43 (3): 1481-1496. ( PubMed, DOI )

Takahashi Naohiro, Kikuchi Hiroaki, Usui Ayaka, Furusho Taisuke, Fujimaru Takuya, Fujiki Tamami, Yanagi Tomoki, Matsuura Yoshiaki, Asano Kenichi, Yamamoto Kouhei, Ando Fumiaki, Susa Koichiro, Mandai Shintaro, Mori Takayasu, Rai Tatemitsu, Uchida Shinichi, Arita Makoto, Sohara Eisei. Deletion of Alox15 improves kidney dysfunction and inhibits fibrosis by increased PGD(2) in the kidney CLINICAL AND EXPERIMENTAL NEPHROLOGY. 2021.05; 25 (5): 445-455. ( PubMed, DOI )

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Fujimaru T, Kawanishi K, Mori T, Mishima E, Sekine A, Chiga M, Mizui M, Sato N, Yanagita M, Ooki Y, Nagahama K, Ohnuki Y, Hamano N, Watanabe S, Mochizuki T, Nagatsuji K, Tanaka K, Tsukamoto T, Tsushima H, Shimamoto M, Tsuji T, Kuyama T, Kawamoto S, Maki K, Katsuma A, Oishi M, Yamamoto K, Mandai S, Kikuchi H, Ando F, Mori Y, Susa K, Iimori S, Naito S, Rai T, Hoshino J, Ubara Y, Miyazaki M, Nagata M, Uchida S, Sohara E. Genetic Background and Clinicopathologic Features of Adult-onset Nephronophthisis. Kidney international reports. 2021.05; 6 (5): 1346-1354. ( PubMed, DOI )

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Mori Takehiko, Saburi Masuho, Hagihara Maki, Mori Masaaki, Yamazaki Rie, Kato Jun. Long-term remission of cryopyrin-associated periodic syndrome after allogeneic haematopoietic stem cell transplantation ANNALS OF THE RHEUMATIC DISEASES. 2021.04; 80 (4): 542-+. ( DOI )

Ota Yoshihide, Noguchi Tadahide, Ariji Eiichiro, Fushimi Chihiro, Fuwa Nobukazu, Harada Hiroyuki, Hayashi Takafumi, Hayashi Ryuichi, Honma Yoshitaka, Miura Masahiko, Mori Taisuke, Nagatsuka Hitoshi, Okura Masaya, Ueda Michihiro, Uzawa Narikazu, Yagihara Kazuhiro, Yagishita Hisao, Yamashiro Masashi, Yanamoto Souichi, Kirita Tadaaki. General rules for clinical and pathological studies on oral cancer (2nd edition): a synopsis INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY. 2021.04; 26 (4): 623-635. ( DOI )

Tao K, Awazu M, Honda M, Shibata H, Mori T, Uchida S, Hasegawa T, Ishii T. An infant with congenital nephrogenic diabetes insipidus presenting with hypercalcemia and hyperphosphatemia. Endocrinology, diabetes & metabolism case reports. 2021.04; 2021 ( PubMed, DOI )

Onoe Tamehito, Hara Satoshi, Yamada Kazunori, Zoshima Takeshi, Mizushima Ichiro, Ito Kiyoaki, Mori Takayasu, Daimon Shoichiro, Muramoto Hiroaki, Shimizu Maki, Iguchi Akira, Kuma Akihiro, Ubara Yoshifumi, Mitobe Michihiro, Tsuruta Hiroaki, Kishimoto Nao, Imura Junko, Konoshita Tadashi, Kawano Mitsuhiro. Significance of kidney biopsy in autosomal dominant tubulointerstitial kidney disease-UMOD: is kidney biopsy truly nonspecific? BMC NEPHROLOGY. 2021.01; 22 (1): 1. ( PubMed, DOI )

Takayasu Mori, Motoko Chiga, Takuya Fujimaru, Ryosuke Kawamoto, Shintaro Mandai, Azuma Nanamatsu, Naohiro Nomura, Fumiaki Ando, Koichiro Susa, Eisei Sohara, Tatemitsu Rai, Shinichi Uchida. Phenotypic differences of mutation-negative cases in Gitelman syndrome clinically diagnosed in adulthood. Hum Mutat. 2020.12; ( PubMed, DOI )

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Takashi Iijima, Takayasu Mori, Eisei Sohara, Tatsuya Suwabe, Junichi Hoshino, Yoshifumi Ubara. A patient with congenital nephrogenic diabetes insipidus due to AVPR2 mutation complicated by persisting polydipsia under hemodialysis treatment. CEN Case Rep. 2020.10; ( PubMed, DOI )

Fujii Shinya, Kikuchi Eriko, Watanabe Yuko, Suzuyama Honoka, Ishigami-Yuasa Mari, Mori Takayasu, Isobe Kiyoshi, Uchida Shinichi, Kagechika Hiroyuki. Structural development of N-(4-phenoxyphenyl)benzamide derivatives as novel SPAK inhibitors blocking WNK kinase signaling BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 2020.09; 30 (17): 127408. ( PubMed, DOI )

Mishima E, Mori T, Nakajima Y, Toyohara T, Kikuchi K, Oikawa Y, Matsuhashi T, Maeda Y, Suzuki T, Kudo M, Ito S, Sohara E, Uchida S, Abe T. HPRT-related hyperuricemia with a novel p.V35M mutation in HPRT1 presenting familial juvenile gout. CEN case reports. 2020.08; 9 (3): 210-214. ( PubMed, DOI )

Sekine A, Hoshino J, Fujimaru T, Suwabe T, Mizuno H, Kawada M, Hiramatsu R, Hasegawa E, Yamanouchi M, Hayami N, Mandai S, Chiga M, Kikuchi H, Ando F, Mori T, Sohara E, Uchida S, Sawa N, Takaichi K, Ubara Y. Genetics May Predict Effectiveness of Tolvaptan in Autosomal Dominant Polycystic Kidney Disease. American journal of nephrology. 2020.08; 51 (9): 1-7. ( PubMed, DOI )

Nakano Kiyoshi, Kubota Yasuo, Mori Takayuki, Chiga Motoko, Mori Takayasu, Sonoda Shyunya, Ueda Daisuke, Asakura Isao, Ikegaya Takeshi, Kagawa Jiro, Uchida Shinichi, Kubota Akira. Familial cases of pseudohypoaldosteronism typeIIharboring a novel mutation in theCullin 3gene NEPHROLOGY. 2020.08; 25 (11): e13752-821. ( PubMed, DOI )

Murata Yoichi, Uchida Soshi, Utsunomiya Hajime, Hatakeyama Akihisa, Nakashima Hirotaka, Mori Toshiharu, Yamanaka Yoshiaki, Tsukamoto Manabu, Sekiya Ichiro, Huard Johnny, Philippon Marc J., Sakai Akinori. Differentiation Potential of Synovial Mesenchymal Stem Cells Isolated From Hip Joints Affected by Femoroacetabular Impingement Syndrome Versus Osteoarthritis ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY. 2020.08; 36 (8): 2122-2133. ( DOI )

Tsuji Kiyokazu, Kitamura Mineaki, Muta Kumiko, Mochizuki Yasushi, Mori Takayasu, Sohara Eisei, Uchida Shinichi, Sakai Hideki, Mukae Hiroshi, Nishino Tomoya. Transplantation of a kidney with a heterozygous mutation in the SLC22A12 (URAT1) gene causing renal hypouricemia: a case report BMC NEPHROLOGY. 2020.07; 21 (1): 282. ( PubMed, DOI )

Moena Ishikawa, Yumi Tada, Hiromu Tanaka, Wataru Morii, Masako Inaba, Hidetoshi Takada, Takayasu Mori, Emiko Noguchi. A Family with Gitelman Syndrome with Asymptomatic Phenotypes while Carrying Reported SLC12A3 Mutations. Case Rep Nephrol Dial. 2020.07; 10 (2): 71-78. ( PubMed, DOI )

Shigemizu Daichi, Mori Taiki, Akiyama Shintaro, Higaki Sayuri, Watanabe Hiroshi, Sakurai Takashi, Niida Shumpei, Ozaki Kouichi. Identification of potential blood biomarkers for early diagnosis of Alzheimer's disease through RNA sequencing analysis ALZHEIMERS RESEARCH & THERAPY. 2020.07; 12 (1): ( DOI )

Shoda Wakana, Nomura Naohiro, Ando Fumiaki, Tagashira Hideaki, Iwamoto Takahiro, Ohta Akihito, Isobe Kiyoshi, Mori Takayasu, Susa Koichiro, Sohara Eisei, Rai Tatemitsu, Uchida Shinichi. Sodium-calcium exchanger 1 is the key molecule for urinary potassium excretion against acute hyperkalemia PLOS ONE. 2020.06; 15 (6): e0235360. ( PubMed, DOI )

Umene R, Kitamura M, Arai H, Matsumura K, Ishimaru Y, Maeda K, Uramatsu T, Obata Y, Mori T, Sohara E, Uchida S, Nishino T. Bartter syndrome representing digenic-based salt-losing tubulopathies presumably accelerated by renal insufficiency. CEN case reports. 2020.06; 9 (4): 375-379. ( PubMed, DOI )

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Ikeda Takashi, Mori Keita, Kawamura Koji, Mori Takehiko, Hagiwara Shotaro, Ueda Yasunori, Kahata Kaoru, Uchida Naoyuki, Tsukada Nobuhiro, Murakami Satoshi, Yamamoto Masahide, Takahashi Tsutomu, Ichinohe Tatsuo, Onizuka Makoto, Atsuta Yoshiko, Kanda Yoshinobu, Okamoto Shinichiro, Sunami Kazutaka, Takamatsu Hiroyuki. Comparison between autologous and allogeneic stem cell transplantation as salvage therapy for multiple myeloma relapsing/progressing after autologous stem cell transplantation HEMATOLOGICAL ONCOLOGY. 2019.12; 37 (5): 586-594. ( DOI )

Chinen T, Saeki E, Mori T, Sohara E, Uchida S, Akimoto T. A case of Gitelman syndrome: our experience with a patient treated in clinical practice on a local island. Journal of rural medicine : JRM. 2019.11; 14 (2): 258-262. ( PubMed, DOI )

Furuto Yoshitaka, Kawamura Mariko, Namikawa Akio, Takahashi Hiroko, Shibuya Yuko, Mori Takayasu, Sohara Eisei. Non-urate transporter 1, non-glucose transporter member 9-related renal hypouricemia and acute renal failure accompanied by hyperbilirubinemia after anaerobic exercise: a case report BMC NEPHROLOGY. 2019.11; 20 (1): 433. ( PubMed, DOI )

Akihisa T, Sato M, Wakayama Y, Taneda S, Horita S, Hirose O, Makabe S, Kataoka H, Mori T, Sohara E, Uchida S, Nitta K, Mochizuki T. Glomerular Basement Membrane Protein Expression and the Diagnosis and Prognosis of Autosomal Dominant Alport Syndrome. Kidney medicine. 2019.11; 1 (6): 391-396. ( PubMed, DOI )

Yoshiaki Matsuura, Naohiro Nomura, Wakana Shoda, Takayasu Mori, Kiyoshi Isobe, Koichiro Susa, Fumiaki Ando, Eisei Sohara, Tatemitsu Rai, Shinichi Uchida. Tacrolimus ameliorates the phenotypes of type 4 Bartter syndrome model mice through activation of sodium-potassium-2 chloride cotransporter and sodium-chloride cotransporter. Biochem. Biophys. Res. Commun.. 2019.09; 517 (2): 364-368. ( PubMed, DOI )

Nagai Norihiro, Ayaki Masahiko, Yanagawa Tatsuo, Hattori Atsuhiko, Negishi Kazuno, Mori Takuro, Nakamura Takahiro J., Tsubota Kazuo. Suppression of Blue Light at Night Ameliorates Metabolic Abnormalities by Controlling Circadian Rhythms INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2019.09; 60 (12): 3786-3793. ( DOI )

Sakoh Takashi, Sekine Akinari, Mori Takayasu, Mizuno Hiroki, Kawada Masahiro, Hiramatsu Rikako, Hasegawa Eiko, Hayami Noriko, Yamanouchi Masayuki, Suwabe Tatsuya, Sawa Naoki, Ubara Yoshifumi, Fujimaru Takuya, Sohara Eisei, Shinichi Uchida, Hoshino Junichi, Takaichi Kenmei. A familial case of pseudohypoaldosteronism type II (PHA2) with a novel mutation (D564N) in the acidic motif in WNK4 MOLECULAR GENETICS & GENOMIC MEDICINE. 2019.06; 7 (6): e705. ( PubMed, DOI )

Ohkubo Atsushi, Okado Tomokazu, Sakurasawa Takatoshi, Maeda Takuma, Itagaki Ayako, Yamamoto Hiroko, Miyamoto Satoko, Seshima Hiroshi, Kurashima Naoki, Mori Takayasu, Iimori Soichiro, Sohara Eisei, Rai Tatemitsu, Uchida Shinichi, Naito Shotaro. Removal Characteristics of Immunoadsorption with the Tryptophan-Immobilized Column Using Conventional and Selective Plasma Separators in the Treatment of Myasthenia Gravis THERAPEUTIC APHERESIS AND DIALYSIS. 2019.06; 23 (3): 271-278. ( PubMed, DOI )

Fujiki Tamami, Ando Fumiaki, Murakami Kana, Isobe Kiyoshi, Mori Takayasu, Susa Koichiro, Nomura Naohiro, Sohara Eisei, Rai Tatemitsu, Uchida Shinichi. Tolvaptan activates the Nrf2/HO-1 antioxidant pathway through PERK phosphorylation SCIENTIFIC REPORTS. 2019.06; 9 (1): 9245. ( PubMed, DOI )

Ohkubo Atsushi, Okado Tomokazu, Sakurasawa Takatoshi, Maeda Takuma, Itagaki Ayako, Yamamoto Hiroko, Miyamoto Satoko, Seshima Hiroshi, Kurashima Naoki, Mori Takayasu, Iimori Soichiro, Sohara Eisei, Rai Tatemitsu, Uchida Shinichi, Naito Shotaro. 重症筋無力症の治療における通常型および選択的血漿分離器を用いたトリプトファン固定化カラムによる免疫吸着の除去特性(Removal Characteristics of Immunoadsorption with the Tryptophan-Immobilized Column Using Conventional and Selective Plasma Separators in the Treatment of Myasthenia Gravis) Therapeutic Apheresis and Dialysis. 2019.06; 23 (3): 271-278. ( ichushi )

Asanomi Yuya, Shigemizu Daichi, Miyashita Akinori, Mitsumori Risa, Mori Taiki, Hara Norikazu, Ito Kaoru, Niida Shumpei, Ikeuchi Takeshi, Ozaki Kouichi. A rare functional variant of SHARPIN attenuates the inflammatory response and associates with increased risk of late-onset Alzheimer's disease MOLECULAR MEDICINE. 2019.06; 25 ( DOI )

Tanaka Tatsuhiko, Oki Eishin, Mori Takayasu, Tsuruga Kazushi, Sohara Eisei, Uchida Shinichi, Tanaka Hiroshi. COMPLETE CLINICAL RESOLUTION OF A JAPANESE FAMILY WITH RENAL PSEUDOHYPOALDOSTERONISM TYPE 1 DUE TO A NOVEL NR3C2 MUTATION NEPHROLOGY. 2019.04; 24 (4): 489-+. ( PubMed, DOI )

Saki Watanabe, Jun Ino, Takuya Fujimaru, Sekiko Taneda, Taro Akihisa, Shiho Makabe, Hiroshi Kataoka, Takayasu Mori, Eisei Sohara, Shinichi Uchida, Kosaku Nitta, Toshio Mochizuki. PKD1 mutation may epistatically ameliorate nephronophthisis progression in patients with NPHP1 deletion. Clin Case Rep. 2019.02; 7 (2): 336-339. ( PubMed, DOI )

Kikuchi Hiroaki, Sasaki Emi, Nomura Naohiro, Mori Takayasu, Minamishima Yoji Andrew, Yoshizaki Yuki, Takahashi Naohiro, Furusho Taisuke, Arai Yohei, Mandai Shintaro, Yamashita Takahiro, Ando Fumiaki, Maejima Yasuhiro, Isobe Kiyoshi, Okado Tomokazu, Rai Tatemitsu, Uchida Shinichi, Sohara Eisei. Failure to sense energy depletion may be a novel therapeutic target in chronic kidney disease KIDNEY INTERNATIONAL. 2019.01; 95 (1): 123-137. ( PubMed, DOI )

Mandai Shintaro, Sato Hidehiko, Iimori Soichiro, Naito Shotaro, Tanaka Haruna, Ando Fumiaki, Susa Koichiro, Isobe Kiyoshi, Mori Takayasu, Nomura Naohiro, Sohara Eisei, Okado Tomokazu, Uchida Shinichi, Fushimi Kiyohide, Rai Tatemitsu. Nationwide in-hospital mortality following major fractures among hemodialysis patients and the general population: An observational cohort BONE. 2019.01; 130 115122. ( PubMed, DOI )

Sekine Akinari, Fujimaru Takuya, Hoshino Junichi, Suwabe Tatsuya, Oguro Masahiko, Mizuno Hiroki, Kawada Masahiro, Sumida Keiichi, Hiramatsu Rikako, Hasegawa Eiko, Yamanouchi Masayuki, Hayami Noriko, Mandai Shintaro, Chiga Motoko, Kikuchi Hiroaki, Ando Fumiaki, Mori Takayasu, Sohara Eisei, Uchida Shinichi, Sawa Naoki, Takaichi Kenmei, Ubara Yoshifumi. Genotype-Clinical Correlations in Polycystic Kidney Disease with No Apparent Family History AMERICAN JOURNAL OF NEPHROLOGY. 2019; 49 (3): 233-240. ( PubMed, DOI )

Ayumi Matsumoto, Isao Matsui, Takayasu Mori, Yusuke Sakaguchi, Masayuki Mizui, Yoshiyasu Ueda, Atsushi Takahashi, Yohei Doi, Karin Shimada, Satoshi Yamaguchi, Keiichi Kubota, Nobuhiro Hashimoto, Tatsufumi Oka, Yoshitsugu Takabatake, Eisei Sohara, Takayuki Hamano, Shinichi Uchida, Yoshitaka Isaka. Severe Osteomalacia with Dent Disease Caused by a Novel Intronic Mutation of the CLCN5 gene. Intern. Med.. 2018.12; 57 (24): 3603-3610.

Kikuchi Hiroaki, Kanda Eiichiro, Mori Takayasu, Sato Hidehiko, Iimori Soichiro, Nomura Naohiro, Naito Shotaro, Sohara Eisei, Okado Tomokazu, Uchida Shinichi, Fushimi Kiyohide, Rai Tatemitsu. Short-term prognosis of emergently hospitalized dialysis-independent chronic kidney disease patients: A nationwide retrospective cohort study in Japan PLOS ONE. 2018.11; 13 (11): e0208258. ( PubMed, DOI )

Osumi Tomoo, Mori Takeshi, Ueyama Jun-Ichi, Fukano Reiji, Sekimizu Masahiro, Takagi Masatoshi, Yagasaki Hiroshi, Nishimura Ryosei, Ikeda Junji, Ogura Taemi, Fujimura Junya, Kobayashi Ryoji. Intrathecal or intraventricular infusion of rituximab for children with B-cell lymphoid malignancies and central nervous system disease BRITISH JOURNAL OF HAEMATOLOGY. 2018.09; 182 72.

Ayumi Matsumoto, Isao Matsui, Takayasu Mori, Yusuke Sakaguchi, Masayuki Mizui, Yoshiyasu Ueda, Atsushi Takahashi, Yohei Doi, Karin Shimada, Satoshi Yamaguchi, Keiichi Kubota, Nobuhiro Hashimoto, Tatsufumi Oka, Yoshitsugu Takabatake, Eisei Sohara, Takayuki Hamano, Shinichi Uchida, Yoshitaka Isaka. A Case of Severe Osteomalacia with Dent Disease Caused by a Novel Intronic Mutation of the CLCN5 gene. Intern. Med.. 2018.08; 57 (24): 3603-3610. ( PubMed, DOI )

Fujimaru T., Mori T., Sekine A., Mandai S., Chiga M., Kikuchi H., Ando F., Mori Y., Nomura N., Iimori S., Naito S., Okado T., Rai T., Hoshino J., Ubara Y., Uchida S., Sohara E.. Kidney enlargement and multiple liver cyst formation implicate mutations in PKD1/2 in adult sporadic polycystic kidney disease CLINICAL GENETICS. 2018.07; 94 (1): 125-131. ( DOI )

Takahashi Hiroyuki, Kajiwara Ryosuke, Kato Motohiro, Hasegawa Daisuke, Tomizawa Daisuke, Noguchi Yasushi, Koike Kazutoshi, Toyama Daisuke, Yabe Hiromasa, Kajiwara Michiko, Fujimura Junya, Sotomatsu Manabu, Ota Setsuo, Maeda Miho, Goto Hiroaki, Kato Yoko, Mori Tetsuya, Inukai Takeshi, Shimada Hiroyuki, Fukushima Keitaro, Ogawa Chitose, Makimoto Atsushi, Fukushima Takashi, Ohki Kentaro, Koh Katsuyoshi, Kiyokawa Nobutaka, Manabe Atsushi, Ohara Akira. Treatment outcome of children with acute lymphoblastic leukemia: the Tokyo Children's Cancer Study Group (TCCSG) Study L04-16 INTERNATIONAL JOURNAL OF HEMATOLOGY. 2018.07; 108 (1): 98-108. ( DOI )

Satoko Miyamoto, Atsushi Ohkubo, Hiroshi Seshima, Hiroko Yamamoto, Ayako Itagaki, Takuma Maeda, Naoki Kurashima, Takayasu Mori, Soichiro Iimori, Shotaro Naito, Eisei Sohara, Tatemitsu Rai, Shinichi Uchida, Tomokazu Okado. Removal Dynamics of Autoantibodies, Immunoglobulins, and Coagulation Factors by Selective Plasma Exchange on Three Consecutive Days. Ther Apher Dial. 2018.06; 22 (3): 255-260. ( PubMed, DOI )

Sayaka Yoshida, Yuya Araki, Takayasu Mori, Emi Sasaki, Yuri Kasagi, Kiyoshi Isobe, Koichiro Susa, Yuichi Inoue, Pascale Bomont, Tomokazu Okado, Tatemitsu Rai, Shinichi Uchida, Eisei Sohara. Decreased KLHL3 expression is involved in the pathogenesis of pseudohypoaldosteronism type II caused by cullin 3 mutation in vivo. Clin. Exp. Nephrol.. 2018.06; 22 (6): 1251-1257. ( PubMed, DOI )

Shintaro Mandai, Takayasu Mori, Naohiro Nomura, Taisuke Furusho, Yohei Arai, Hiroaki Kikuchi, Emi Sasaki, Eisei Sohara, Tatemitsu Rai, Shinichi Uchida. WNK1 regulates skeletal muscle cell hypertrophy by modulating the nuclear localization and transcriptional activity of FOXO4. Sci Rep. 2018.06; 8 (1): 9101. ( PubMed, DOI )

Ogawa Nami, Mori Takashi, Fujishima Ichiro, Wakabayashi Hidetaka, Itoda Masataka, Kunieda Kenjiro, Shigematsu Takashi, Nishioka Shinta, Tohara Haruka, Yamada Minoru, Ogawa Sumito. Ultrasonography to Measure Swallowing Muscle Mass and Quality in Older Patients With Sarcopenic Dysphagia JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2018.06; 19 (6): 516-522. ( DOI )

Naoya Toriu, Hiroki Mizuno, Naoki Sawa, Keiichi Sumida, Tatsuya Suwabe, Noriko Hayami, Akinari Sekine, Masayuki Yamanouchi, Junichi Hoshino, Kenmei Takaichi, Motoko Yanagita, Takuya Fujimaru, Takayasu Mori, Eisei Sohara, Shinichi Uchida, Yoshifumi Ubara. Everolimus Reduces the Size of Tuberous Sclerosis Complex-Related Huge Renal Angiomyolipomas Exceeding 20 cm in the Longest Diameter. Case Rep Oncol. 2018.05; 11 (2): 258-267. ( PubMed, DOI )

Hashimoto Hiroko, Nomura Naohiro, Shoda Wakana, Isobe Kiyoshi, Kikuchi Hiroaki, Yamamoto Kouhei, Fujimaru Takuya, Ando Fumiaki, Mori Takayasu, Okado Tomokazu, Rai Tatemitsu, Uchida Shinichi, Sohara Eisei. Metformin increases urinary sodium excretion by reducing phosphorylation of the sodium- chloride cotransporter. Metabolism. 2018.03; 85 23-31. ( PubMed, DOI )

Takada Daisuke, Sekine Akinari, Yabuuchi Junko, Kogure Yuta, Ueno Toshiharu, Yamanouchi Masayuki, Sumida Keiichi, Suwabe Tatsuya, Hayami Noriko, Hoshino Junichi, Takaichi Kenmei, Kinowaki Keiichi, Fujii Takeshi, Ohashi Kenichi, Mori Takayasu, Sohara Eisei, Uchida Shinichi, Ubara Yoshifumi. Renal histology and MRI in a 25-year-old Japanese man with nephronophthisis 4. Clin Nephrol. 2018.03; 89 (3): 223-228. ( PubMed, DOI )

Shintaro Mandai, Hidehiko Sato, Soichiro Iimori, Shotaro Naito, Takayasu Mori, Daiei Takahashi, Moko Zeniya, Naohiro Nomura, Eisei Sohara, Tomokazu Okado, Shinichi Uchida, Kiyohide Fushimi, Tatemitsu Rai. Dialysis Case Volume Associated With In-Hospital Mortality in Maintenance Dialysis Patients. Kidney Int Rep. 2018.03; 3 (2): 356-363. ( PubMed, DOI )

Miura Yuka, Nakagami Gojiro, Yabunaka Koichi, Tohara Haruka, Noguchi Hiroshi, Mori Taketoshi, Sanada Hiromi. A Randomized Controlled Trial to Investigate the Effectiveness of the Prevention of Aspiration Pneumonia Using Recommendations for Swallowing Care Guided by Ultrasound Examination HEALTHCARE. 2018.03; 6 (1): ( DOI )

Mori Takayasu, Yousefzadeh Matthew J, Faridounnia Maryam, Chong Jessica X, Hisama Fuki M, Hudgins Louanne, Mercado Gabriela, Wade Erin A, Barghouthy Amira S, Lee Lin, Martin George M, Nickerson Deborah A, Bamshad Michael J, Niedernhofer Laura J, Oshima Junko, University of Washington Center for Mendelian Genomics. ERCC4 variants identified in a cohort of patients with segmental progeroid syndromes. Hum Mutat. 2018.02; 39 (2): 255-265. ( PubMed, DOI )

Mishima Eikan, Mori Takayasu, Sohara Eisei, Uchida Shinichi, Abe Takaaki, Ito Sadayoshi. Inherited, not acquired, Gitelman syndrome in a patient with Sjogren's syndrome: importance of genetic testing to distinguish the two forms. CEN Case Rep. 2017.11; 6 (2): 180-184. ( PubMed, DOI )

Ito Yusuke, Sekine Akinari, Takada Daisuke, Yabuuchi Junko, Kogure Yuta, Ueno Toshiharu, Sumida Keiichi, Yamanouchi Masayuki, Hayami Noriko, Suwabe Tatsuya, Hoshino Junichi, Sawa Naoki, Takaichi Kenmei, Kinowaki Keiichi, Fujii Takeshi, Ohashi Kenichi, Kikuchi Hiroaki, Mandai Shintaro, Chiga Motoko, Mori Takayasu, Sohara Eisei, Uchida Shinichi, Ubara Yoshifumi. Renal histology and MRI findings in a 37-year-old Japanese patient with autosomal recessive polycystic kidney disease. Clin Nephrol. 2017.11; 88 (11): 292-297. ( PubMed, DOI )

Mishima Eikan, Mori Takayasu, Sohara Eisei, Uchida Shinichi, Abe Takaaki, Ito Sadayoshi. シェーグレン症候群患者における後天性でなく遺伝性のGitelman症候群　遺伝形質の鑑別における遺伝子変異解析の重要性(Inherited, not acquired, Gitelman syndrome in a patient with Sjoegren's syndrome: importance of genetic testing to distinguish the two forms) CEN Case Reports. 2017.11; 6 (2): 180-184. ( ichushi )

Zeniya Moko, Mori Takayasu, Yui Naofumi, Nomura Naohiro, Mandai Shintaro, Isobe Kiyoshi, Chiga Motoko, Sohara Eisei, Rai Tatemitsu, Uchida Shinichi. The proteasome inhibitor bortezomib attenuates renal fibrosis in mice via the suppression of TGF-beta1. Sci Rep. 2017.10; 7 (1): 13086. ( PubMed, DOI )

Nojima K., Namiki T., Funazumi M., Ishikawa M., Kaneko Y., Tanemura A., Katamaya I., Mori T., Yamazaki N., Yokozeki H., Hearing V.. NUAK2 over expressed and DNA copy number increased in acral melanoma: Its significance on the survival of patients JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2017.10; 137 (10): S296.

Ishigami-Yuasa Mari, Watanabe Yuko, Mori Takayasu, Masuno Hiroyuki, Fujii Shinya, Kikuchi Eriko, Uchida Shinichi, Kagechika Hiroyuki. Development of WNK signaling inhibitors as a new class of antihypertensive drugs. Bioorg Med Chem. 2017.07; 25 (14): 3845-3852. ( PubMed, DOI )

Yoshizaki Yuki, Mori Takayasu, Ishigami-Yuasa Mari, Kikuchi Eriko, Takahashi Daiei, Zeniya Moko, Nomura Naohiro, Mori Yutaro, Araki Yuya, Ando Fumiaki, Mandai Shintaro, Kasagi Yuri, Arai Yohei, Sasaki Emi, Yoshida Sayaka, Kagechika Hiroyuki, Rai Tatemitsu, Uchida Shinichi, Sohara Eisei. Drug-Repositioning Screening for Keap1-Nrf2 Binding Inhibitors using Fluorescence Correlation Spectroscopy. Sci Rep. 2017.06; 7 (1): 3945. ( PubMed, DOI )

Kasagi Yuri, Takahashi Daiei, Aida Tomomi, Nishida Hidenori, Nomura Naohiro, Zeniya Moko, Mori Takayasu, Sasaki Emi, Ando Fumiaki, Rai Tatemitsu, Uchida Shinichi, Sohara Eisei. Impaired degradation of medullary WNK4 in the kidneys of KLHL2 knockout mice. Biochem Biophys Res Commun. 2017.05; 487 (2): 368-374. ( PubMed, DOI )

Mandai Shintaro, Furukawa Susumu, Kodaka Manami, Hata Yutaka, Mori Takayasu, Nomura Naohiro, Ando Fumiaki, Mori Yutaro, Takahashi Daiei, Yoshizaki Yuki, Kasagi Yuri, Arai Yohei, Sasaki Emi, Yoshida Sayaka, Furuichi Yasuro, Fujii Nobuharu L, Sohara Eisei, Rai Tatemitsu, Uchida Shinichi. Loop diuretics affect skeletal myoblast differentiation and exercise-induced muscle hypertrophy. Sci Rep. 2017.04; 7 46369. ( PubMed, DOI )

Takahashi Daiei, Mori Takayasu, Sohara Eisei, Tanaka Miyako, Chiga Motoko, Inoue Yuichi, Nomura Naohiro, Zeniya Moko, Ochi Hiroki, Takeda Shu, Suganami Takayoshi, Rai Tatemitsu, Uchida Shinichi. WNK4 is an Adipogenic Factor and Its Deletion Reduces Diet-Induced Obesity in Mice. EBioMedicine. 2017.04; 18 118-127. ( PubMed, DOI )

Sasaki Emi, Susa Koichiro, Mori Takayasu, Isobe Kiyoshi, Araki Yuya, Inoue Yuichi, Yoshizaki Yuki, Ando Fumiaki, Mori Yutaro, Mandai Shintaro, Zeniya Moko, Takahashi Daiei, Nomura Naohiro, Rai Tatemitsu, Uchida Shinichi, Sohara Eisei. KLHL3 Knockout Mice Reveal the Physiological Role of KLHL3 and the Pathophysiology of Pseudohypoaldosteronism Type II Caused by Mutant KLHL3. Mol Cell Biol. 2017.04; 37 (7): ( PubMed, DOI )

Shoda Wakana, Nomura Naohiro, Ando Fumiaki, Mori Yutaro, Mori Takayasu, Sohara Eisei, Rai Tatemitsu, Uchida Shinichi. Calcineurin inhibitors block sodium-chloride cotransporter dephosphorylation in response to high potassium intake. Kidney Int. 2017.02; 91 (2): 402-411. ( PubMed, DOI )

Mori Takayasu, Hosomichi Kazuyoshi, Chiga Motoko, Mandai Shintaro, Nakaoka Hirofumi, Sohara Eisei, Okado Tomokazu, Rai Tatemitsu, Sasaki Sei, Inoue Ituro, Uchida Shinichi. Comprehensive genetic testing approach for major inherited kidney diseases, using next-generation sequencing with a custom panel. Clin Exp Nephrol. 2017.02; 21 (1): 63-75. ( PubMed, DOI )

Purizaca-Rosillo Nelson, Mori Takayasu, Benites-Condor Yamali, Hisama Fuki M, Martin George M, Oshima Junko. High incidence of BSCL2 intragenic recombinational mutation in Peruvian type 2 Berardinelli-Seip syndrome. Am J Med Genet A. 2017.02; 173 (2): 471-478. ( PubMed, DOI )

Yokote Koutaro, Chanprasert Sirisak, Lee Lin, Eirich Katharina, Takemoto Minoru, Watanabe Aki, Koizumi Naoko, Lessel Davor, Mori Takayasu, Hisama Fuki M, Ladd Paula D, Angle Brad, Baris Hagit, Cefle Kivanc, Palanduz Sukru, Ozturk Sukru, Chateau Antoinette, Deguchi Kentaro, Easwar T K M, Federico Antonio, Fox Amy, Grebe Theresa A, Hay Beverly, Nampoothiri Sheela, Seiter Karen, Streeten Elizabeth, Pina-Aguilar Raul E, Poke Gemma, Poot Martin, Posmyk Renata, Martin George M, Kubisch Christian, Schindler Detlev, Oshima Junko. WRN Mutation Update: Mutation Spectrum, Patient Registries, and Translational Prospects. Hum Mutat. 2017.01; 38 (1): 7-15. ( PubMed, DOI )

Takehara Eriko, Mandai Shintaro, Shikuma Satomi, Akita Wataru, Chiga Motoko, Mori Takayasu, Oda Takashi, Kuwahara Michio, Uchida Shinichi. Post-infectious Proliferative Glomerulonephritis with Monoclonal Immunoglobulin G Deposits Associated with Complement Factor H Mutation. Intern Med. 2017.01; 56 (7): 811-817. ( PubMed, DOI )

Imai Eri, Kaneko Shuzo, Mori Takayasu, Okado Tomokazu, Uchida Shinichi, Tsukamoto Yusuke. Erratum: A novel heterozygous mutation in the ATP6V0A4 gene encoding the V-ATPase a4 subunit in an adult patient with incomplete distal renal tubular acidosis. Clin Kidney J. 2016.12; 9 (6): 871. ( PubMed, DOI )

Ando Fumiaki, Sohara Eisei, Morimoto Tetsuji, Yui Naofumi, Nomura Naohiro, Kikuchi Eriko, Takahashi Daiei, Mori Takayasu, Vandewalle Alain, Rai Tatemitsu, Sasaki Sei, Kondo Yoshiaki, Uchida Shinichi. Wnt5a induces renal AQP2 expression by activating calcineurin signalling pathway. Nat Commun. 2016.11; 7 13636. ( PubMed, DOI )

Imai Eri, Kaneko Shuzo, Mori Takayasu, Okado Tomokazu, Uchida Shinichi, Tsukamoto Yusuke. A novel heterozygous mutation in the ATP6V0A4 gene encoding the V-ATPase a4 subunit in an adult patient with incomplete distal renal tubular acidosis. Clin Kidney J. 2016.06; 9 (3): 424-428. ( PubMed, DOI )

Kusuda Takeshi, Hosoya Tadashi, Mori Takayasu, Ihara Katsuhito, Nishida Hidenori, Chiga Motoko, Sohara Eisei, Rai Tatemitsu, Koike Ryuji, Uchida Shinichi, Kohsaka Hitoshi. Acquired Gitelman Syndrome in an Anti-SSA Antibody-positive Patient with a SLC12A3 Heterozygous Mutation. Intern Med. 2016.01; 55 (21): 3201-3204. ( PubMed, DOI )

Mandai Shintaro, Mori Takayasu, Sohara Eisei, Rai Tatemitsu, Uchida Shinichi. Generation of Hypertension-Associated STK39 Polymorphism Knockin Cell Lines With the Clustered Regularly Interspaced Short Palindromic Repeats/Cas9 System. Hypertension. 2015.12; 66 (6): 1199-1206. ( PubMed, DOI )

Kikuchi Hiroaki, Mori Takayasu, Rai Tatemitsu, Uchida Shinichi. Acute kidney injury caused by sarcoid granulomatous interstitial nephritis without extrarenal manifestations. CEN Case Rep. 2015.11; 4 (2): 212-217. ( PubMed, DOI )

Mori Yutaro, Mori Takayasu, Wakabayashi Mai, Yoshizaki Yuki, Zeniya Moko, Sohara Eisei, Rai Tatemitsu, Uchida Shinichi. Involvement of selective autophagy mediated by p62/SQSTM1 in KLHL3-dependent WNK4 degradation. Biochem J. 2015.11; 472 (1): 33-41. ( PubMed, DOI )

Yoshizaki Yuki, Mori Yutaro, Tsuzaki Yoshihito, Mori Takayasu, Nomura Naohiro, Wakabayashi Mai, Takahashi Daiei, Zeniya Moko, Kikuchi Eriko, Araki Yuya, Ando Fumiaki, Isobe Kiyoshi, Nishida Hidenori, Ohta Akihito, Susa Koichiro, Inoue Yuichi, Chiga Motoko, Rai Tatemitsu, Sasaki Sei, Uchida Shinichi, Sohara Eisei. Impaired degradation of WNK by Akt and PKA phosphorylation of KLHL3. Biochem Biophys Res Commun. 2015.11; 467 (2): 229-234. ( PubMed, DOI )

Araki Yuya, Rai Tatemitsu, Sohara Eisei, Mori Takayasu, Inoue Yuichi, Isobe Kiyoshi, Kikuchi Eriko, Ohta Akihito, Sasaki Sei, Uchida Shinichi. Generation and analysis of knock-in mice carrying pseudohypoaldosteronism type II-causing mutations in the cullin 3 gene. Biol Open. 2015.10; 4 (11): 1509-1517. ( PubMed, DOI )

Zeniya Moko, Morimoto Nobuhisa, Takahashi Daiei, Mori Yutaro, Mori Takayasu, Ando Fumiaki, Araki Yuya, Yoshizaki Yuki, Inoue Yuichi, Isobe Kiyoshi, Nomura Naohiro, Oi Katsuyuki, Nishida Hidenori, Sasaki Sei, Sohara Eisei, Rai Tatemitsu, Uchida Shinichi. Kelch-Like Protein 2 Mediates Angiotensin II-With No Lysine 3 Signaling in the Regulation of Vascular Tonus. J Am Soc Nephrol. 2015.09; 26 (9): 2129-2138. ( PubMed, DOI )

Kikuchi Eriko, Mori Takayasu, Zeniya Moko, Isobe Kiyoshi, Ishigami-Yuasa Mari, Fujii Shinya, Kagechika Hiroyuki, Ishihara Tomoaki, Mizushima Tohru, Sasaki Sei, Sohara Eisei, Rai Tatemitsu, Uchida Shinichi. Discovery of Novel SPAK Inhibitors That Block WNK Kinase Signaling to Cation Chloride Transporters. J Am Soc Nephrol. 2015.07; 26 (7): 1525-1536. ( PubMed, DOI )

Susa Koichiro, Sohara Eisei, Rai Tatemitsu, Zeniya Moko, Mori Yutaro, Mori Takayasu, Chiga Motoko, Nomura Naohiro, Nishida Hidenori, Takahashi Daiei, Isobe Kiyoshi, Inoue Yuichi, Takeishi Kenta, Takeda Naoki, Sasaki Sei, Uchida Shinichi. Impaired degradation of WNK1 and WNK4 kinases causes PHAII in mutant KLHL3 knock-in mice. Hum Mol Genet. 2014.10; 23 (19): 5052-5060. ( PubMed, DOI )

Takahashi Daiei, Mori Takayasu, Nomura Naohiro, Khan Muhammad Zakir Hossain, Araki Yuya, Zeniya Moko, Sohara Eisei, Rai Tatemitsu, Sasaki Sei, Uchida Shinichi. WNK4 is the major WNK positively regulating NCC in the mouse kidney. Biosci Rep. 2014.05; 34 (3): ( PubMed, DOI )

Isobe Kiyoshi, Mori Takayasu, Asano Takako, Kawaguchi Hiroyuki, Nonoyama Shigeaki, Kumagai Naonori, Kamada Fumiaki, Morimoto Tetsuji, Hayashi Matsuhiko, Sohara Eisei, Rai Tatemitsu, Sasaki Sei, Uchida Shinichi. Development of enzyme-linked immunosorbent assays for urinary thiazide-sensitive Na-Cl cotransporter measurement. Am J Physiol Renal Physiol. 2013.11; 305 (9): F1374-F1381. ( PubMed, DOI )

Mori Takayasu, Kikuchi Eriko, Watanabe Yuko, Fujii Shinya, Ishigami-Yuasa Mari, Kagechika Hiroyuki, Sohara Eisei, Rai Tatemitsu, Sasaki Sei, Uchida Shinichi. Chemical library screening for WNK signalling inhibitors using fluorescence correlation spectroscopy. Biochem J. 2013.11; 455 (3): 339-345. ( PubMed, DOI )

Zeniya Moko, Sohara Eisei, Kita Satomi, Iwamoto Takahiro, Susa Koichiro, Mori Takayasu, Oi Katsuyuki, Chiga Motoko, Takahashi Daiei, Yang Sung-Sen, Lin Shih-Hua, Rai Tatemitsu, Sasaki Sei, Uchida Shinichi. Dietary salt intake regulates WNK3-SPAK-NKCC1 phosphorylation cascade in mouse aorta through angiotensin II. Hypertension. 2013.11; 62 (5): 872-878. ( PubMed, DOI )

Mori Yutaro, Wakabayashi Mai, Mori Takayasu, Araki Yuya, Sohara Eisei, Rai Tatemitsu, Sasaki Sei, Uchida Shinichi. Decrease of WNK4 ubiquitination by disease-causing mutations of KLHL3 through different molecular mechanisms. Biochem Biophys Res Commun. 2013.09; 439 (1): 30-34. ( PubMed, DOI )

Takahashi Daiei, Mori Takayasu, Wakabayashi Mai, Mori Yutaro, Susa Koichiro, Zeniya Moko, Sohara Eisei, Rai Tatemitsu, Sasaki Sei, Uchida Shinichi. KLHL2 interacts with and ubiquitinates WNK kinases. Biochem Biophys Res Commun. 2013.08; 437 (3): 457-462. ( PubMed, DOI )

Yoshioka Wakako, Mori Takayasu, Nagahama Kiyotaka, Tamura Teiichi. Biopsy-proven drug-induced tubulointerstitial nephritis in a patient with acute kidney injury and alcoholic severe acute pancreatitis. BMJ Case Rep. 2013.05; 2013 ( PubMed, DOI )

Wakabayashi Mai, Mori Takayasu, Isobe Kiyoshi, Sohara Eisei, Susa Koichiro, Araki Yuya, Chiga Motoko, Kikuchi Eriko, Nomura Naohiro, Mori Yutaro, Matsuo Hiroshi, Murata Tomohiro, Nomura Shinsuke, Asano Takako, Kawaguchi Hiroyuki, Nonoyama Shigeaki, Rai Tatemitsu, Sasaki Sei, Uchida Shinichi. Impaired KLHL3-mediated ubiquitination of WNK4 causes human hypertension. Cell Rep. 2013.03; 3 (3): 858-868. ( PubMed, DOI )

Hara Y, Ando F, Oikawa D, Ichimura K, Fujiki T, Mandai S, Mori T, Susa K, Sohara E, Rai T, Tokunaga F, Uchida S. LRBA Is Essential for Urinary Concentration and Body Water Homeostasis. ASN Kidney Week 2022 2022.11

Yanagi T, Kikuchi H, Takeuchi K, Susa K, Takahashi N, Nakano Y, Ando F, Mandai S, Mori T, Honda S, Torii S, Shimizu S, Rai T, Uchida S, Sohara E. ULK1-Regulated AMP Sensing Mechanism by AMPK Is Disrupted in CKD. ASN Kidney Week 2022 2022.11 Orland

Suzuki S, Ando F, Hara Y, Fujiki T, Mandai S, Susa K, Mori T, Sohara E, Rai T, Uchida S. ZNF185 Prevents Stress Fiber Formation Through the Inhibition of RhoA in Endothelial Cells. ASN Kidney Week 2022 2022.11

Kanamori T, Udagawa T, Murakoshi M, Adachi E, Okutsu M, Mori T, Sohara E, Uchida S. A Missense Mutation in Zinc Finger 4 of WT1 Might Lead to Focal Segmental Glomerular Sclerosis due to Its Mislocalization and Downstream Dysregulation. ASN Kidney Week 2022 2022.11 Orland

Shimohata Homare, Miyake Yusuke, Yoshida Yu, Usui Joichi, Mori Takayasu, Sohara Eisei, Uchida Shinichi, Hirayama Kouichi, Kobayashi Masaki. 電顕所見でミエリン像を認めたLMX1B関連腎症(LMX1B-associated nephropathy that showed myelin figures on electron microscopy). CEN Case Reports 2021.11.01

Nanamatsu A, Mori T, Ando F, Furusho T, Mandai S, Susa K, Sohara E, Rai T, Uchida S. Vasopressin induces urinary uromodulin secretion by activating protein kinase A. ASN Kidney Week 2021 2021.11 San Diego/web

Oe Yuji, Mishima Eikan, Mori Takayasu, Okamoto Koji, Honkura Yohei, Nagasawa Tasuku, Yoshida Mai, Sato Hiroshi, Suzuki Jun, Ikeda Ryoukichi, Sohara Eisei, Uchida Shinichi, Katori Yukio, Miyazaki Mariko. LMX1Bの新規変異(p.Pro219Ala)はアルポート症候群様表現型の巣状分節性糸球体硬化症を引き起こす(A Novel Mutation in LMX1B(p.Pro219Ala) Causes Focal Segmental Glomerulosclerosis with Alport Syndrome-like Phenotype). Internal Medicine 2021.09.01

Mandai Shintaro, Ando Fumiaki, Mori Takayasu, Susa Koichiro, Iimori Soichiro, Naito Shotaro, Sohara Eisei, Uchida Shinichi, Fushimi Kiyohide, Rai Tatemitsu. 腎臓病に関する入院理由と死因の不一致がもたらす負荷　日本人成人に関する全国調査(Burden of Kidney Disease on Discrepancy between Reasons for Admission and Death:A Nationwide Cohort Study of Japanese Adults). 日本腎臓学会誌 2021.06.01

Takahashi Naohiro, Kikuchi Hiroaki, Usui Ayaka, Furusho Taisuke, Fujimaru Takuya, Fujiki Tamami, Yanagi Tomoki, Matsuura Yoshiaki, Asano Kenichi, Yamamoto Kouhei, Ando Fumiaki, Susa Koichiro, Mandai Shintaro, Mori Takayasu, Rai Tatemitsu, Uchida Shinichi, Arita Makoto, Sohara Eisei. ALOX15の欠損は腎臓でのPGD2の増加により腎機能障害を改善し線維化を抑制する(Deletion of Alox15 improves kidney dysfunction and inhibits fibrosis by increased PGD2 in the kidney). Clinical and Experimental Nephrology 2021.05.01

Iijima Takashi, Mori Takayasu, Sohara Eisei, Suwabe Tatsuya, Hoshino Junichi, Ubara Yoshifumi. 血液透析下で持続性多渇症を呈したAVPR2変異による先天性腎性尿崩症の1例(A patient with congenital nephrogenic diabetes insipidus due to AVPR2 mutation complicated by persisting polydipsia under hemodialysis treatment). CEN Case Reports 2021.05.01

Takedani Kai, Notsu Masakazu, Koike Sayo, Yamauchi Mika, Mori Takayasu, Sohara Eisei, Yamauchi Asuka, Yoshikane Kaori, Ito Takafumi, Kanasaki Keizo. ビタミンD欠損症を伴った非定型腎尿細管性アシドーシスによる骨軟化症　症例報告(Osteomalacia caused by atypical renal tubular acidosis with vitamin D deficiency: a case report). CEN Case Reports 2021.05.01

Umene Ryusuke, Kitamura Mineaki, Arai Hideyuki, Matsumura Kazuki, Ishimaru Yuka, Maeda Kanenori, Uramatsu Tadashi, Obata Yoko, Mori Takayasu, Sohara Eisei, Uchida Shinichi, Nishino Tomoya. 腎機能障害により悪化した2遺伝子性の塩類喪失性尿細管機能異常症を呈したBartter症候群(Bartter syndrome representing digenic-based salt-losing tubulopathies presumably accelerated by renal insufficiency). CEN Case Reports 2020.11.01

Mishima Eikan, Mori Takayasu, Nakajima Yoko, Toyohara Takafumi, Kikuchi Koichi, Oikawa Yoshitsugu, Matsuhashi Tetsuro, Maeda Yasuhiro, Suzuki Takehiro, Kudo Masataka, Ito Sadayoshi, Sohara Eisei, Uchida Shinichi, Abe Takaaki. 家族性若年性痛風を呈したHPRT1の新規p.V35M変異を伴うHPRT関連高尿酸血症(HPRT-related hyperuricemia with a novel p.V35M mutation in HPRT1 presenting familial juvenile gout). CEN Case Reports 2020.08.01

Chinen Takashi, Saeki Eiji, Mori Takayasu, Sohara Eisei, Uchida Shinichi, Akimoto Tetsu. Gitelman症候群の1例　離島における診療経験(A case of Gitelman syndrome: our experience with a patient treated in clinical practice on a local island). Journal of Rural Medicine 2019.11.01

Mori T, Chiga M, Fujimaru T, Mandai S, Nanamatsu A, Sohara E, Rai T, Uchida S. More than half of patients clinically diagnosed as Gitelman syndrome in adulthood do not have causal mutations in known pathogenic genes. ASN Kidney Week 2019 2019.11

Yoshida Sayaka, Araki Yuya, Mori Takayasu, Sasaki Emi, Kasagi Yuri, Isobe Kiyoshi, Susa Koichiro, Inoue Yuichi, Bomont Pascale, Okado Tomokazu, Rai Tatemitsu, Uchida Shinichi, Sohara Eisei. KLHL3の発現低下はcullin 3のin vivoでの変異によって引き起こされる偽性低アルドステロン症II型の病態発生に関与する(Decreased KLHL3 expression is involved in the pathogenesis of pseudohypoaldosteronism type II caused by cullin 3 mutation in vivo). Clinical and Experimental Nephrology 2018.12.01

Matsumoto Ayumi, Matsui Isao, Mori Takayasu, Sakaguchi Yusuke, Mizui Masayuki, Ueda Yoshiyasu, Takahashi Atsushi, Doi Yohei, Shimada Karin, Yamaguchi Satoshi, Kubota Keiichi, Hashimoto Nobuhiro, Oka Tatsufumi, Takabatake Yoshitsugu, Sohara Eisei, Hamano Takayuki, Uchida Shinichi, Isaka Yoshitaka. CLCN5遺伝子の新規イントロン変異を原因とするDent病を伴った重症骨軟化症(Severe Osteomalacia with Dent Disease Caused by a Novel Intronic Mutation of the CLCN5 gene). Internal Medicine 2018.12.01

Fujiki T, Ando F, Isobe K, Mori T, Susa K, Nomura N, Sohara E, Rai T, Uchida S.. Tolvaptan activates Nrf2/HO-1 pathway through PERK phosphorylation.. ASN Kidney Week 2018. 2018.10

Sohara E, Mori T, Uchida S.. Development and application of comprehensive genetic testing system for major inherited kidney diseases, using next-generation sequencing with custom panels.. 20th Nephrology Symposium. 2018.10

Takahashi N, Kikuchi H, Ishihara T, Arita M, Furusho T, Ando F, Mori T, Isobe K, Susa K, Nomura N, Rai T, Uchida S, Sohara E.. Amelioration of Renal Fibrosis and Tubulointerstitial Damage in Fat-1 Transgenic CKD Mice by Compensation of Decreased Omega-3 Fatty Acids in the Kidney.. ASN Kidney Week 2018. 2018.10

Shoda W, Nomura N, Ando F, Isobe K, Mori T, Susa K, Sohara E, Rai T, Uchida S.. Molecular mechanism of high-potassium induced Na-Cl cotransporter dephosphorylation.. ASN Kidney Week 2018. 2018.10

Mandai S, Mori T, Nomura N, Furusho T, Arai Y, Kikuchi H, Sasaki E, Sohara E, Rai T, Uchida S.. WNK1 Regulates Skeletal Muscle Hypertrophy by Modulating Phosphorylation, Nuclear Localization, and Transcriptional Activity of FoxO4.. ASN Kidney Week 2018. 2018.10

Hashimoto H, Nomura N, Shoda W, Isobe K, Kikuchi H, Yamamoto K, Fujimaru T, Ando F, Mori T, Okado T, Rai T, Uchida S, Sohara E.. Metformin has natriuretic effects through reduction of the sodium-chrolide cotransporter phosphorylation.. ASN Kidney Week 2018. 2018.10

Furusho T, Sohara E, Mandai S, Kikuchi H, Ando F, Zeniya M, Mori T, Nomura N, Rai T, Uchida S.. WNK1-SPAK-NCC signaling cascade is involved in salt sensitive hypertension induced by aristolochic acid nephropathy.. ASN Kidney Week 2018. 2018.10

4. Fujimaru T, Mori T, Mandai S, Chiga M, Kikuchi H, Ando F, Mori Y, Susa K, Isobe K, Iimori S, Nomura N, Naito S, Okado T, Rai T, Nagatsuji K, Nagahama K, Mishima E, Mochizuki T, Sekine A, Hoshino J, Ubara Y, Uchida S, Sohara E.. Genomic Background of Adults with Suspected Ciliopathy on Renal Biopsy.. ASN Kidney Week 2018. 2018.10

Mori T. Genome big data will open the way of the future in nephrology.. 5th Next Generation Kidney Research Meeting, Tokyo 2018.08.18

Miyamoto Satoko, Ohkubo Atsushi, Seshima Hiroshi, Yamamoto Hiroko, Itagaki Ayako, Maeda Takuma, Kurashima Naoki, Mori Takayasu, Iimori Soichiro, Naito Shotaro, Sohara Eisei, Rai Tatemitsu, Uchida Shinichi, Okado Tomokazu. 連続3日間の選択的血漿交換療法による自己抗体、免疫グロブリンおよび凝固因子の除去ダイナミクス(Removal Dynamics of Autoantibodies, Immunoglobulins, and Coagulation Factors by Selective Plasma Exchange on Three Consecutive Days). Therapeutic Apheresis and Dialysis 2018.06.01

5. Fujimaru T, Mori T, Sekine A, Mandai S, Chiga M, Kikuchi H, Ando F, Nomura N, Iimori S, Naito S, Okado T, Rai T, Hoshino J, Ubara Y, Uchida S, Sohara E.. Genomic diagnosis of adult polycystic kidney disease with no family history.. ISN Frontiers Meetings 2018. 2018.02

Takayasu Mori, Motoko Chiga, Takuya Fujimaru, Shintaro Mandai, Shota Watanabe, Yasuhisa Nakamura, Takehiro Morishita, Osamu Uemura, Eri Imai, Shuzo Kaneko, Yusuke Tsukamoto, Eisei Sohara, Tatemitsu Rai, Shinichi Uchida. We propose single heterozygous mutation in ATP6V0A4 as novel genetic cause of dRTA. The 50th Annual Meeting of the American Society of Nephrology 2017.11.02 New Orleans, LA.

Takehara Eriko, Mandai Shintaro, Shikuma Satomi, Akita Wataru, Chiga Motoko, Mori Takayasu, Oda Takashi, Kuwahara Michio, Uchida Shinichi. 補体因子H変異を伴うモノクローナル免疫グロブリンG沈着症を合併する感染後増殖性糸球体腎炎(Post-infectious Proliferative Glomerulonephritis with Monoclonal Immunoglobulin G Deposits Associated with Complement Factor H Mutation). Internal Medicine 2017.04.01

Mori Takayasu, Hosomichi Kazuyoshi, Chiga Motoko, Mandai Shintaro, Nakaoka Hirofumi, Sohara Eisei, Okado Tomokazu, Rai Tatemitsu, Sasaki Sei, Inoue Ituro, Uchida Shinichi. カスタムパネルによる次世代シーケンシングを用いた主要な遺伝性腎疾患に対する包括的遺伝子検査手法(Comprehensive genetic testing approach for major inherited kidney diseases, using next-generation sequencing with a custom panel). Clinical and Experimental Nephrology 2017.02.01

Mori T, Uchida S, Nickerson DA, Bamshad MJ, Chong JX and University of Washington Center for Mendelian Genomics.. Using maximum allele frequencies across populations greatly increases power for Mendelian gene discovery.. American Society of Human Genetics (ASHG) 2016 Annual Meeting. 2016.10.01 Vancouver

Takayasu Mori, Kazuyoshi Hosomichi, Eisei Sohara, Tatemitsu Rai, Sei Sasaki, Ituro Inoue, Shinichi Uchida.. Comprehensive diagnosis of hereditary kidney diseases by a customized diagnostic panel of targeted exome sequencing.. The 47th Annual Meeting of the American Society of Nephrology 2014.11 Philadelphia

Mori T, Eriko K, Sohara E, Rai T, Sasaki S, Uchida S.. Chemical library screening for WNK signaling inhibitors by using fluorescent correlation spectroscopy.. The 46th Annual Meeting of American Society of Nephrology, Atlanta 2013.11.01

Wakabayashi M, Mori T (co-first), Isobe K, Sohara E, Susa K, Araki Y, Chiga M, Kikuchi E, Nomura N, Mori Y, Matsuo H, Murata T, Nomura S, Asano T, Kawaguchi H, Nonoyama S, Rai T, Sasaki S, Uchida S.. Impaired KLHL3-Mediated Ubiquitination of WNK4 Activates OSR1 and SPAK Kinases-NaCl Cotransporter (NCC) Signaling and Causes Hypertension.. The 46th Annual Meeting of American Society of Nephrology, Atlanta 2013.11.01

Mori T, Sohara E, Rai T, Sasaki S, Uchida S.. Generation and analysis of WT-WNK4 transgenic mice revealed the physiological role of WNK4. The 45th Annual Meeting of American Society of Nephrology, San Diego. The 45th Annual Meeting of American Society of Nephrology, San Diego 2012.11.01

Mori T, Ohta A, Sohara E, Rai T, Sasaki S, Uchida S.. High throughput screening of drugs that inhibit WNK-OSR1/SPAK signaling cascade.. The 44th Annual Meeting of American Society of Nephrology, Philadelphia 2011.11.01 Philadelphia