Yumi Inagaki, Takuya Ogawa, Makoto J Tabata, Yuki Nagata, Ryo Watanabe, Tatsuo Kawamoto, Keiji Moriyama, Toshihiro Tanaka. Correction to: Identification of OPN3 as associated with non-syndromic oligodontia in a Japanese population. J Hum Genet. 2022.04; 67 (4): 245. ( PubMed, DOI )

Yuki Sagawa, Takuya Ogawa, Yusuke Matsuyama, Junka Nakagawa Kang, Miyu Yoshizawa Araki, Yuko Unnai Yasuda, Tsasan Tumurkhuu, Ganjargal Ganburged, Amarsaikhan Bazar, Toshihiro Tanaka, Takeo Fujiwara, Keiji Moriyama. Association between Smoking during Pregnancy and Short Root Anomaly in Offspring. Int J Environ Res Public Health. 2021.11; 18 (21): ( PubMed, DOI )

Yumi Inagaki, Takuya Ogawa, Makoto J Tabata, Yuki Nagata, Ryo Watanabe, Tatsuo Kawamoto, Keiji Moriyama, Toshihiro Tanaka. Identification of OPN3 as associated with non-syndromic oligodontia in a Japanese population. J Hum Genet. 2021.08; 66 (8): 769-775. ( PubMed, DOI )

Todd A Johnson, Yoichi Mashimo, Jer-Yuarn Wu, Dankyu Yoon, Akira Hata, Michiaki Kubo, Atsushi Takahashi, Tatsuhiko Tsunoda, Kouichi Ozaki, Toshihiro Tanaka, Kaoru Ito, Hiroyuki Suzuki, Hiromichi Hamada, Tohru Kobayashi, Toshiro Hara, Chien-Hsiun Chen, Yi-Ching Lee, Yi-Min Liu, Li-Ching Chang, Chun-Ping Chang, Young-Mi Hong, Gi-Young Jang, Sin-Weon Yun, Jeong-Jin Yu, Kyung-Yil Lee, Jae-Jung Kim, Taesung Park, , Jong-Keuk Lee, Yuan-Tsong Chen, Yoshihiro Onouchi. Association of an IGHV3-66 gene variant with Kawasaki disease. J Hum Genet. 2021.05; ( PubMed, DOI )

Kazuyoshi Ishigaki, Masato Akiyama, Masahiro Kanai, Atsushi Takahashi, Eiryo Kawakami, Hiroki Sugishita, Saori Sakaue, Nana Matoba, Siew-Kee Low, Yukinori Okada, Chikashi Terao, Tiffany Amariuta, Steven Gazal, Yuta Kochi, Momoko Horikoshi, Ken Suzuki, Kaoru Ito, Satoshi Koyama, Kouichi Ozaki, Shumpei Niida, Yasushi Sakata, Yasuhiko Sakata, Takashi Kohno, Kouya Shiraishi, Yukihide Momozawa, Makoto Hirata, Koichi Matsuda, Masashi Ikeda, Nakao Iwata, Shiro Ikegawa, Ikuyo Kou, Toshihiro Tanaka, Hidewaki Nakagawa, Akari Suzuki, Tomomitsu Hirota, Mayumi Tamari, Kazuaki Chayama, Daiki Miki, Masaki Mori, Satoshi Nagayama, Yataro Daigo, Yoshio Miki, Toyomasa Katagiri, Osamu Ogawa, Wataru Obara, Hidemi Ito, Teruhiko Yoshida, Issei Imoto, Takashi Takahashi, Chizu Tanikawa, Takao Suzuki, Nobuaki Sinozaki, Shiro Minami, Hiroki Yamaguchi, Satoshi Asai, Yasuo Takahashi, Ken Yamaji, Kazuhisa Takahashi, Tomoaki Fujioka, Ryo Takata, Hideki Yanai, Akihide Masumoto, Yukihiro Koretsune, Hiromu Kutsumi, Masahiko Higashiyama, Shigeo Murayama, Naoko Minegishi, Kichiya Suzuki, Kozo Tanno, Atsushi Shimizu, Taiki Yamaji, Motoki Iwasaki, Norie Sawada, Hirokazu Uemura, Keitaro Tanaka, Mariko Naito, Makoto Sasaki, Kenji Wakai, Shoichiro Tsugane, Masayuki Yamamoto, Kazuhiko Yamamoto, Yoshinori Murakami, Yusuke Nakamura, Soumya Raychaudhuri, Johji Inazawa, Toshimasa Yamauchi, Takashi Kadowaki, Michiaki Kubo, Yoichiro Kamatani. Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Nat Genet. 2020.07; 52 (7): 669-679. ( PubMed, DOI )

Yoshiki Higashijima, Yusuke Matsui, Teppei Shimamura, Ryo Nakaki, Nao Nagai, Shuichi Tsutsumi, Yohei Abe, Verena M Link, Mizuko Osaka, Masayuki Yoshida, Ryo Watanabe, Toshihiro Tanaka, Akashi Taguchi, Mai Miura, Xiaoan Ruan, Guoliang Li, Tsuyoshi Inoue, Masaomi Nangaku, Hiroshi Kimura, Tetsushi Furukawa, Hiroyuki Aburatani, Youichiro Wada, Yijun Ruan, Christopher K Glass, Yasuharu Kanki. Coordinated demethylation of H3K9 and H3K27 is required for rapid inflammatory responses of endothelial cells. EMBO J. 2020.04; 39 (7): e103949. ( PubMed, DOI )

Kyaw Thiha, Yoichi Mashimo, Hiroyuki Suzuki, Hiromichi Hamada, Akira Hata, Toshiro Hara, Toshihiro Tanaka, Kaoru Ito, Yoshihiro Onouchi, . Correction to: Investigation of novel variations of ORAI1 gene and their association with Kawasaki disease. J Hum Genet. 2019.10; 64 (10): 1049. ( PubMed, DOI )

Yusuke Ebana, Yihan Sun, Xiaoxi Yang, Taiju Watanabe, Satoru Makita, Kouichi Ozaki, Toshihiro Tanaka, Hirokuni Arai, Tetsushi Furukawa. Pathway analysis with genome-wide association study (GWAS) data detected the association of atrial fibrillation with the mTOR signaling pathway. Int J Cardiol Heart Vasc. 2019.09; 24 100383. ( PubMed, DOI )

Chisato Shimizu, Jihoon Kim, Hariklia Eleftherohorinou, Victoria J Wright, Long T Hoang, Adriana H Tremoulet, Alessandra Franco, Martin L Hibberd, Atsushi Takahashi, Michiaki Kubo, Kaoru Ito, Toshihiro Tanaka, Yoshihiro Onouchi, Lachlan J M Coin, Michael Levin, Jane C Burns, Hiroko Shike, . HLA-C variants associated with amino acid substitutions in the peptide binding groove influence susceptibility to Kawasaki disease. Hum. Immunol.. 2019.09; 80 (9): 731-738. ( PubMed, DOI )

Yujiro Nakano, Takanobu Yoshimoto, Ryo Watanabe, Masanori Murakami, Tatsuya Fukuda, Kazutaka Saito, Yasuhisa Fujii, Takumi Akashi, Toshihiro Tanaka, Tetsuya Yamada, Mitsuhide Naruse, Yoshihiro Ogawa. miRNA299 involvement in CYP11B2 expression in aldosterone-producing adenoma. Eur. J. Endocrinol.. 2019.07; 181 (1): 69-78. ( PubMed, DOI )

Kyaw Thiha, Yoichi Mashimo, Hiroyuki Suzuki, Hiromichi Hamada, Akira Hata, Toshiro Hara, Toshihiro Tanaka, Kaoru Ito, Yoshihiro Onouchi, . Investigation of novel variations of ORAI1 gene and their association with Kawasaki disease. J. Hum. Genet.. 2019.06; 64 (6): 511-519. ( PubMed, DOI )

Wataru Shimizu, Hisaki Makimoto, Kenichiro Yamagata, Tsukasa Kamakura, Mitsuru Wada, Koji Miyamoto, Yuko Inoue-Yamada, Hideo Okamura, Kohei Ishibashi, Takashi Noda, Satoshi Nagase, Aya Miyazaki, Heima Sakaguchi, Isao Shiraishi, Takeru Makiyama, Seiko Ohno, Hideki Itoh, Hiroshi Watanabe, Kenshi Hayashi, Masakazu Yamagishi, Hiroshi Morita, Masao Yoshinaga, Yoshiyasu Aizawa, Kengo Kusano, Yoshihiro Miyamoto, Shiro Kamakura, Satoshi Yasuda, Hisao Ogawa, Toshihiro Tanaka, Naotaka Sumitomo, Nobuhisa Hagiwara, Keiichi Fukuda, Satoshi Ogawa, Yoshifusa Aizawa, Naomasa Makita, Tohru Ohe, Minoru Horie, Takeshi Aiba. Association of Genetic and Clinical Aspects of Congenital Long QT Syndrome With Life-Threatening Arrhythmias in Japanese Patients. JAMA Cardiol. 2019.03; 4 (3): 246-254. ( PubMed, DOI )

El Rouby N, McDonough CW, Gong Y, McClure LA, Mitchell BD, Horenstein RB, Talbert RL, Crawford DC; eMERGE network, Gitzendanner MA, Takahashi A, Tanaka T, Kubo M, Pepine CJ, Cooper-DeHoff RM, Benavente OR, Shuldiner AR, Johnson JA.. Genome-wide association analysis of common genetic variants of resistant hypertension. Pharmacogenomics J. 2018.09; ( DOI )

Roselli C, Chaffin MD, Weng LC, Aeschbacher S, Ahlberg G, Albert CM, Almgren P, Alonso A, Anderson CD, Aragam KG, Arking DE, Barnard J, Bartz TM, Benjamin EJ, Bihlmeyer NA, Bis JC, Bloom HL, Boerwinkle E, Bottinger EB, Brody JA, Calkins H, Campbell A, Cappola TP, Carlquist J, Chasman DI, Chen LY, Chen YI, Choi EK, Choi SH, Christophersen IE, Chung MK, Cole JW, Conen D, Cook J, Crijns HJ, Cutler MJ, Damrauer SM, Daniels BR, Darbar D, Delgado G, Denny JC, Dichgans M, Dörr M, Dudink EA, Dudley SC, Esa N, Esko T, Eskola M, Fatkin D, Felix SB, Ford I, Franco OH, Geelhoed B, Grewal RP, Gudnason V, Guo X, Gupta N, Gustafsson S, Gutmann R, Hamsten A, Harris TB, Hayward C, Heckbert SR, Hernesniemi J, Hocking LJ, Hofman A, Horimoto ARVR, Huang J, Huang PL, Huffman J, Ingelsson E, Ipek EG, Ito K, Jimenez-Conde J, Johnson R, Jukema JW, Kääb S, Kähönen M, Kamatani Y, Kane JP, Kastrati A, Kathiresan S, Katschnig-Winter P, Kavousi M, Kessler T, Kietselaer BL, Kirchhof P, Kleber ME, Knight S, Krieger JE, Kubo M, Launer LJ, Laurikka J, Lehtimäki T, Leineweber K, Lemaitre RN, Li M, Lim HE, Lin HJ, Lin H, Lind L, Lindgren CM, Lokki ML, London B, Loos RJF, Low SK, Lu Y, Lyytikäinen LP, Macfarlane PW, Magnusson PK, Mahajan A, Malik R, Mansur AJ, Marcus GM, Margolin L, Margulies KB, März W, McManus DD5, Melander O, Mohanty S, Montgomery JA, Morley MP, Morris AP, Müller-Nurasyid M, Natale A, Nazarian S, Neumann B, Newton-Cheh C, Niemeijer MN, Nikus K, Nilsson P, Noordam R, Oellers H, Olesen MS, Orho-Melander M, Padmanabhan S, Pak HN, Paré G, Pedersen NL, Pera J, Pereira A, Porteous D, Psaty BM, Pulit SL, Pullinger CR, Rader DJ, Refsgaard L, Ribasés M, Ridker PM, Rienstra M, Risch L, Roden DM, Rosand J, Rosenberg MA, Rost N, Rotter JI, Saba S, Sandhu RK, Schnabel RB, Schramm K, Schunkert H, Schurman C, Scott SA, Seppälä I, Shaffer C, Shah S, Shalaby AA, Shim J, Shoemaker MB, Siland JE, Sinisalo J, Sinner MF, Slowik A, Smith AV, Smith BH, Smith JG, Smith JD, Smith NL, Soliman EZ, Sotoodehnia N, Stricker BH Sun A, Sun H, Svendsen JH, Tanaka T, Tanriverdi K, Taylor KD, Teder-Laving M, Teumer A, Thériault S, Trompet S Tucker NR, Tveit A, Uitterlinden AG, Van Der Harst P, Van Gelder IC, Van Wagoner DR, Verweij N, Vlachopoulou E, Völker U, Wang B, Weeke PE, Weijs B, Weiss R, Weiss S, Wells QS, Wiggins KL, Wong JA, Woo D, Worrall BB, Yang PS, Yao J, Yoneda ZT, Zeller T, Zeng L, Lubitz SA, Lunetta KL, Ellinor PT.. Multi-ethnic genome-wide association study for atrial fibrillation. Nat Genet. 2018.09; 50 (9): 1225-1233. ( DOI )

Hirata J, Hirota T, Ozeki T, Kanai M, Sudo T, Tanaka T, Hizawa N, Nakagawa H, Sato S, Mushiroda T, Saeki H, Tamari M, Okada Y.. Variants at HLA-A, HLA-C, and HLA-DQB1 Confer Risk of Psoriasis Vulgaris in Japanese. J Invest Dermatol. 2018.03; 138 (3): 542-548. ( DOI )

Urayama KY, Takagi M, Kawaguchi T, Matsuo K, Tanaka Y, Ayukawa Y, Arakawa Y, Hasegawa D, Yuza Y, Kaneko T, Noguchi Y, Taneyama Y, Ota S, Inukai T, Yanagimachi M, Keino D, Koike K, Toyama D, Nakazawa Y, Kurosawa H, Nakamura K, Moriwaki K, Goto H, Sekinaka Y, Morita D, Kato M, Takita J, Tanaka T, Inazawa J, Koh K, Ishida Y, Ohara A, Mizutani S, Matsuda F, Manabe A.. Regional evaluation of childhood acute lymphoblastic leukemia genetic susceptibility loci among Japanese. Sci Rep. 2018.01; 8 (1): 789. ( DOI )

McCormack M, Gui H, Ingason A, Speed D, Wright GEB, Zhang EJ, Secolin R, Yasuda C, Kwok M, Wolking S, Becker F, Rau S, Avbersek A, Heggeli K, Leu C, Depondt C, Sills GJ, Marson AG, Auce P, Brodie MJ, Francis B, Johnson MR, Koeleman BPC, Striano P, Coppola A, Zara F, Kunz WS, Sander JW, Lerche H, Klein KM, Weckhuysen S, Krenn M, Gudmundsson LJ, Stefánsson K, Krause R, Shear N, Ross CJD, Delanty N; EPIGEN Consortium;, Pirmohamed M, Carleton BC; Canadian Pharmacogenomics Network for Drug Safety;, Cendes F, Lopes-Cendes I, Liao WP, O'Brien TJ, Sisodiya SM; EpiPGX Consortium;, Cherny S, Kwan P, Baum L; International League Against Epilepsy Consortium on Complex Epilepsies;, Cavalleri GL.. Genetic variation in CFH predicts phenytoin-induced maculopapular exanthema in European-descent patients. Neurology. . 2018.01; 90 (4): e332-e341. ( DOI )

T Sudo, Y Okada, K Ozaki, K Urayama, M Kanai, H Kobayashi, M Gokyu, Y Izumi, T Tanaka. Association of NOD2 Mutations with Aggressive Periodontitis. J. Dent. Res.. 2017.06; 22034517715432. ( PubMed, DOI )

Spracklen Cassandra N, Chen Peng, Kim Young Jin, Wang Xu, Cai Hui, Li Shengxu, Long Jirong, Wu Ying, Wang Ya Xing, Takeuchi Fumihiko, Wu Jer-Yuarn, Jung Keum-Ji, Hu Cheng, Akiyama Koichi, Zhang Yonghong, Moon Sanghoon, Johnson Todd A, Li Huaixing, Dorajoo Rajkumar, He Meian, Cannon Maren E, Roman Tamara S, Salfati Elias, Lin Keng-Hung, Guo Xiuqing, Sheu Wayne H H, Absher Devin, Adair Linda S, Assimes Themistocles L, Aung Tin, Cai Qiuyin, Chang Li-Ching, Chen Chien-Hsiun, Chien Li-Hsin, Chuang Lee-Ming, Chuang Shu-Chun, Du Shufa, Fan Qiao, Fann Cathy S J, Feranil Alan B, Friedlander Yechiel, Gordon-Larsen Penny, Gu Dongfeng, Gui Lixuan, Guo Zhirong, Heng Chew-Kiat, Hixson James, Hou Xuhong, Hsiung Chao Agnes, Hu Yao, Hwang Mi Yeong, Hwu Chii-Min, Isono Masato, Juang Jyh-Ming Jimmy, Khor Chiea-Chuen, Kim Yun Kyoung, Koh Woon-Puay, Kubo Michiaki, Lee I-Te, Lee Sun-Ju, Lee Wen-Jane, Liang Kae-Woei, Lim Blanche, Lim Sing-Hui, Liu Jianjun, Nabika Toru, Pan Wen-Harn, Peng Hao, Quertermous Thomas, Sabanayagam Charumathi, Sandow Kevin, Shi Jinxiu, Sun Liang, Tan Pok Chien, Tan Shu-Pei, Taylor Kent D, Teo Yik-Ying, Toh Sue-Anne, Tsunoda Tatsuhiko, van Dam Rob M, Wang Aili, Wang Feijie, Wang Jie, Wei Wen Bin, Xiang Yong-Bing, Yao Jie, Yuan Jian-Min, Zhang Rong, Zhao Wanting, Chen Yii-Der Ida, Rich Stephen S, Rotter Jerome I, Wang Tzung-Dau, Wu Tangchun, Lin Xu, Han Bok-Ghee, Tanaka Toshihiro, Cho Yoon Shin, Katsuya Tomohiro, Jia Weiping, Jee Sun-Ha, Chen Yuan-Tsong, Kato Norihiro, Jonas Jost B, Cheng Ching-Yu, Shu Xiao-Ou, He Jiang, Zheng Wei, Wong Tien-Yin, Huang Wei, Kim Bong-Jo, Tai E-Shyong, Mohlke Karen L, Sim Xueling. Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels. Hum Mol Genet. 2017.05; 26 (9): 1770-1784. ( PubMed, DOI )

Low Siew-Kee, Takahashi Atsushi, Ebana Yusuke, Ozaki Kouichi, Christophersen Ingrid E, Ellinor Patrick T, Ogishima Soichi, Yamamoto Masayuki, Satoh Mamoru, Sasaki Makoto, Yamaji Taiki, Iwasaki Motoki, Tsugane Shoichiro, Tanaka Keitaro, Naito Mariko, Wakai Kenji, Tanaka Hideo, Furukawa Tetsushi, Kubo Michiaki, Ito Kaoru, Kamatani Yoichiro, Tanaka Toshihiro, AFGen Consortium. Identification of six new genetic loci associated with atrial fibrillation in the Japanese population. Nat Genet. 2017.04; ( PubMed, DOI )

Christophersen Ingrid E, Rienstra Michiel, Roselli Carolina, Yin Xiaoyan, Geelhoed Bastiaan, Barnard John, Lin Honghuang, Arking Dan E, Smith Albert V, Albert Christine M, Chaffin Mark, Tucker Nathan R, Li Molong, Klarin Derek, Bihlmeyer Nathan A, Low Siew-Kee, Weeke Peter E, Muller-Nurasyid Martina, Smith J Gustav, Brody Jennifer A, Niemeijer Maartje N, Dorr Marcus, Trompet Stella, Huffman Jennifer, Gustafsson Stefan, Schurmann Claudia, Kleber Marcus E, Lyytikainen Leo-Pekka, Seppala Ilkka, Malik Rainer, Horimoto Andrea R V R, Perez Marco, Sinisalo Juha, Aeschbacher Stefanie, Theriault Sebastien, Yao Jie, Radmanesh Farid, Weiss Stefan, Teumer Alexander, Choi Seung Hoan, Weng Lu-Chen, Clauss Sebastian, Deo Rajat, Rader Daniel J, Shah Svati H, Sun Albert, Hopewell Jemma C, Debette Stephanie, Chauhan Ganesh, Yang Qiong, Worrall Bradford B, Pare Guillaume, Kamatani Yoichiro, Hagemeijer Yanick P, Verweij Niek, Siland Joylene E, Kubo Michiaki, Smith Jonathan D, Van Wagoner David R, Bis Joshua C, Perz Siegfried, Psaty Bruce M, Ridker Paul M, Magnani Jared W, Harris Tamara B, Launer Lenore J, Shoemaker M Benjamin, Padmanabhan Sandosh, Haessler Jeffrey, Bartz Traci M, Waldenberger Melanie, Lichtner Peter, Arendt Marina, Krieger Jose E, Kahonen Mika, Risch Lorenz, Mansur Alfredo J, Peters Annette, Smith Blair H, Lind Lars, Scott Stuart A, Lu Yingchang, Bottinger Erwin B, Hernesniemi Jussi, Lindgren Cecilia M, Wong Jorge A, Huang Jie, Eskola Markku, Morris Andrew P, Ford Ian, Reiner Alex P, Delgado Graciela, Chen Lin Y, Chen Yii-Der Ida, Sandhu Roopinder K, Li Man, Boerwinkle Eric, Eisele Lewin, Lannfelt Lars, Rost Natalia, Anderson Christopher D, Taylor Kent D, Campbell Archie, Magnusson Patrik K, Porteous David, Hocking Lynne J, Vlachopoulou Efthymia, Pedersen Nancy L, Nikus Kjell, Orho-Melander Marju, Hamsten Anders, Heeringa Jan, Denny Joshua C, Kriebel Jennifer, Darbar Dawood, Newton-Cheh Christopher, Shaffer Christian, Macfarlane Peter W, Heilmann-Heimbach Stefanie, Almgren Peter, Huang Paul L, Sotoodehnia Nona, Soliman Elsayed Z, Uitterlinden Andre G, Hofman Albert, Franco Oscar H, Volker Uwe, Jockel Karl-Heinz, Sinner Moritz F, Lin Henry J, Guo Xiuqing, Dichgans Martin, Ingelsson Erik, Kooperberg Charles, Melander Olle, Loos Ruth J F, Laurikka Jari, Conen David, Rosand Jonathan, van der Harst Pim, Lokki Marja-Liisa, Kathiresan Sekar, Pereira Alexandre, Jukema J Wouter, Hayward Caroline, Rotter Jerome I, Marz Winfried, Lehtimaki Terho, Stricker Bruno H, Chung Mina K, Felix Stephan B, Gudnason Vilmundur, Alonso Alvaro, Roden Dan M, Kaab Stefan, Chasman Daniel I, Heckbert Susan R, Benjamin Emelia J, Tanaka Toshihiro, Lunetta Kathryn L, Lubitz Steven A, Ellinor Patrick T, METASTROKE Consortium of the ISGC. Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. Nat Genet. 2017.04; ( PubMed, DOI )

Yamagata Kenichiro, Horie Minoru, Aiba Takeshi, Ogawa Satoshi, Aizawa Yoshifusa, Ohe Toru, Yamagishi Masakazu, Makita Naomasa, Sakurada Harumizu, Tanaka Toshihiro, Shimizu Akihiko, Hagiwara Nobuhisa, Kishi Ryoji, Nakano Yukiko, Takagi Masahiko, Makiyama Takeru, Ohno Seiko, Fukuda Keiichi, Watanabe Hiroshi, Morita Hiroshi, Hayashi Kenshi, Kusano Kengo, Kamakura Shiro, Yasuda Satoshi, Ogawa Hisao, Miyamoto Yoshihiro, Kapplinger Jamie D, Ackerman Michael J, Shimizu Wataru. Genotype-Phenotype Correlation of SCN5A Mutation for the Clinical and Electrocardiographic Characteristics of Probands with Brugada Syndrome: A Japanese Multicenter Registry. Circulation. 2017.03; ( PubMed, DOI )

Hirata Makoto, Nagai Akiko, Kamatani Yoichiro, Ninomiya Toshiharu, Tamakoshi Akiko, Yamagata Zentaro, Kubo Michiaki, Muto Kaori, Kiyohara Yutaka, Mushiroda Taisei, Murakami Yoshinori, Yuji Koichiro, Furukawa Yoichi, Zembutsu Hitoshi, Tanaka Toshihiro, Ohnishi Yozo, Nakamura Yusuke, Matsuda Koichi, BioBank Japan Cooperative Hospital Group. Overview of BioBank Japan follow-up data in 32 diseases. J Epidemiol. 2017.03; 27 (3S): S22-S28. ( PubMed, DOI )

Hirata Makoto, Kamatani Yoichiro, Nagai Akiko, Kiyohara Yutaka, Ninomiya Toshiharu, Tamakoshi Akiko, Yamagata Zentaro, Kubo Michiaki, Muto Kaori, Mushiroda Taisei, Murakami Yoshinori, Yuji Koichiro, Furukawa Yoichi, Zembutsu Hitoshi, Tanaka Toshihiro, Ohnishi Yozo, Nakamura Yusuke, Matsuda Koichi, BioBank Japan Cooperative Hospital Group. Cross-sectional analysis of BioBank Japan clinical data: A large cohort of 200,000 patients with 47 common diseases. J Epidemiol. 2017.03; 27 (3S): S9-S21. ( PubMed, DOI )

Nagai Akiko, Hirata Makoto, Kamatani Yoichiro, Muto Kaori, Matsuda Koichi, Kiyohara Yutaka, Ninomiya Toshiharu, Tamakoshi Akiko, Yamagata Zentaro, Mushiroda Taisei, Murakami Yoshinori, Yuji Koichiro, Furukawa Yoichi, Zembutsu Hitoshi, Tanaka Toshihiro, Ohnishi Yozo, Nakamura Yusuke, Kubo Michiaki, BioBank Japan Cooperative Hospital Group. Overview of the BioBank Japan Project: Study design and profile. J Epidemiol. 2017.03; 27 (3S): S2-S8. ( PubMed, DOI )

Ebana Yusuke, Ozaki Kouichi, Liu Lian, Hachiya Hitoshi, Hirao Kenzo, Isobe Mitsuaki, Kubo Michiaki, Tanaka Toshihiro, Furukawa Tetsushi. Clinical utility and functional analysis of variants in atrial fibrillation-associated locus 4q25. J Cardiol. 2017.01; ( PubMed, DOI )

Chisato Shimizu, Hariklia Eleftherohorinou, Victoria J Wright, Jihoon Kim, Martin P Alphonse, James C Perry, Rolando Cimaz, David Burgner, Nagib Dahdah, Long T Hoang, Chiea Chuen Khor, Andrea Salgado, Adriana H Tremoulet, Sonia Davila, Taco W Kuijpers, Martin L Hibberd, Todd A Johnson, Atsushi Takahashi, Tatsuhiko Tsunoda, Michiaki Kubo, Toshihiro Tanaka, Yoshihiro Onouchi, Rae S M Yeung, Lachlan J M Coin, Michael Levin, Jane C Burns, . Genetic Variation in the SLC8A1 Calcium Signaling Pathway Is Associated With Susceptibility to Kawasaki Disease and Coronary Artery Abnormalities. Circ Cardiovasc Genet. 2016.12; 9 (6): 559-568. ( PubMed, DOI )

Tumurkhuu T, Fujiwara T, Komazaki Y, Kawaguchi Y, Tanaka T, Inazawa J, Ganburged G, Bazar A, Ogawa T, Moriyama K. Association between maternal education and malocclusion in Mongolian adolescents: a cross-sectional study. BMJ Open. 2016.11; 6 (11):

Lian Liu, Yusuke Ebana, Jun-Ichi Nitta, Yoshihide Takahashi, Shinsuke Miyazaki, Toshihiro Tanaka, Masatoshi Komura, Mitsuaki Isobe, Tetsushi Furukawa. Genetic Variants Associated With Susceptibility to Atrial Fibrillation in a Japanese Population. Can J Cardiol. 2016.11; ( PubMed, DOI )

Mari Ichikawa, Takeshi Aiba, Seiko Ohno, Daichi Shigemizu, Junichi Ozawa, Keiko Sonoda, Megumi Fukuyama, Hideki Itoh, Yoshihiro Miyamoto, Tatsuhiko Tsunoda, Takeru Makiyama, Toshihiro Tanaka, Wataru Shimizu, Minoru Horie. Phenotypic Variability of ANK2 Mutations in Patients With Inherited Primary Arrhythmia Syndromes. Circ. J.. 2016.11; 80 (12): 2435-2442. ( PubMed, DOI )

Tsasan Tumurkhuu, Takeo Fujiwara, Yuko Komazaki, Yoko Kawaguchi, Toshihiro Tanaka, Johji Inazawa, Ganjargal Ganburged, Amarsaikhan Bazar, Takuya Ogawa, Keiji Moriyama. Association between maternal education and malocclusion in Mongolian adolescents: a cross-sectional study. BMJ Open. 2016.11; 6 (11): e012283. ( PubMed, DOI )

Masahiro Kanai, Toshihiro Tanaka, Yukinori Okada. Empirical estimation of genome-wide significance thresholds based on the 1000 Genomes Project data set. J. Hum. Genet.. 2016.10; 61 (10): 861-866. ( PubMed, DOI )

Juliana Bosso Taniguchi, Kanoh Kondo, Kyota Fujita, Xigui Chen, Hidenori Homma, Takeaki Sudo, Ying Mao, Kei Watase, Toshihiro Tanaka, Kazuhiko Tagawa, Takuya Tamura, Shin-Ichi Muramatsu, Hitoshi Okazawa. RpA1 ameliorates symptoms of mutant ataxin-1 knock-in mice and enhances DNA damage repair. Hum. Mol. Genet.. 2016.10; 25 (20): 4432-4447. ( PubMed, DOI )

Nobue Yagihara, Hiroshi Watanabe, Phil Barnett, Laetitia Duboscq-Bidot, Atack C Thomas, Ping Yang, Seiko Ohno, Kanae Hasegawa, Ryozo Kuwano, Stéphanie Chatel, Richard Redon, Jean-Jacques Schott, Vincent Probst, Tamara T Koopmann, Connie R Bezzina, Arthur A M Wilde, Yukiko Nakano, Takeshi Aiba, Yoshihiro Miyamoto, Shiro Kamakura, Dawood Darbar, Brian S Donahue, Daichi Shigemizu, Toshihiro Tanaka, Tatsuhiko Tsunoda, Masayoshi Suda, Akinori Sato, Tohru Minamino, Naoto Endo, Wataru Shimizu, Minoru Horie, Dan M Roden, Naomasa Makita. Variants in the SCN5A Promoter Associated With Various Arrhythmia Phenotypes. J Am Heart Assoc. 2016.09; 5 (9): ( PubMed, DOI )

S-W Chang, C W McDonough, Y Gong, T A Johnson, T Tsunoda, E R Gamazon, M A Perera, A Takahashi, T Tanaka, M Kubo, C J Pepine, J A Johnson, R M Cooper-DeHoff. Genome-wide association study identifies pharmacogenomic loci linked with specific antihypertensive drug treatment and new-onset diabetes. Pharmacogenomics J.. 2016.09; ( PubMed, DOI )

Tanaka Toshihiro, Kimura Akinori. Cardiovascular genetics. J Hum Genet. 2016.01; 61 (1): 1. ( PubMed, DOI )

Konta Atsuko, Ozaki Kouichi, Sakata Yasuhiko, Takahashi Atsushi, Morizono Takashi, Suna Shinichiro, Onouchi Yoshihiro, Tsunoda Tatsuhiko, Kubo Michiaki, Komuro Issei, Eishi Yoshinobu, Tanaka Toshihiro. A functional SNP in FLT1 increases risk of coronary artery disease in a Japanese population. J Hum Genet. 2016.01; ( PubMed, DOI )

Okada Yukinori, Muramatsu Tomoki, Suita Naomasa, Kanai Masahiro, Kawakami Eiryo, Iotchkova Valentina, Soranzo Nicole, Inazawa Johji, Tanaka Toshihiro. Significant impact of miRNA-target gene networks on genetics of human complex traits. Sci Rep. 2016; 6 22223. ( PubMed, DOI )

Onouchi Yoshihiro, Fukazawa Ryuji, Yamamura Kenichiro, Suzuki Hiroyuki, Kakimoto Nobuyuki, Suenaga Tomohiro, Takeuchi Takashi, Hamada Hiromichi, Honda Takafumi, Yasukawa Kumi, Terai Masaru, Ebata Ryota, Higashi Kouji, Saji Tsutomu, Kemmotsu Yasushi, Takatsuki Shinichi, Ouchi Kazunobu, Kishi Fumio, Yoshikawa Tetsushi, Nagai Toshiro, Hamamoto Kunihiro, Sato Yoshitake, Honda Akihito, Kobayashi Hironobu, Sato Junichi, Shibuta Shoichi, Miyawaki Masakazu, Oishi Ko, Yamaga Hironobu, Aoyagi Noriyuki, Yoshiyama Megumi, Miyashita Ritsuko, Murata Yuji, Fujino Akihiro, Ozaki Kouichi, Kawasaki Tomisaku, Abe Jun, Seki Mitsuru, Kobayashi Tohru, Arakawa Hirokazu, Ogawa Shunichi, Hara Toshiro, Hata Akira, Tanaka Toshihiro. Variations in ORAI1 Gene Associated with Kawasaki Disease. PLoS One. 2016; 11 (1): e0145486. ( PubMed, DOI )

Gong Yan, McDonough Caitrin W, Beitelshees Amber L, Rouby Nihal El, Hiltunen Timo P, O'Connell Jeffrey R, Padmanabhan Sandosh, Langaee Taimour Y, Hall Karen, Schmidt Siegfried O F, Curry Robert W Jr, Gums John G, Donner Kati M, Kontula Kimmo K, Bailey Kent R, Boerwinkle Eric, Takahashi Atsushi, Tanaka Toshihiro, Kubo Michiaki, Chapman Arlene B, Turner Stephen T, Pepine Carl J, Cooper-DeHoff Rhonda M, Johnson Julie A. PTPRD gene associated with blood pressure response to atenolol and resistant hypertension. J Hypertens. 2015.11; 33 (11): 2278-2285. ( PubMed, DOI )

Ozaki Kouichi, Tanaka Toshihiro. Molecular genetics of coronary artery disease. J Hum Genet. 2015.07; ( PubMed, DOI )

Lucas Fares-Taie, Sylvie Gerber, Akihiko Tawara, Arturo Ramirez-Miranda, Jean-Yves Douet, Hannah Verdin, Antoine Guilloux, Juan C Zenteno, Hiroyuki Kondo, Hugo Moisset, Bruno Passet, Ken Yamamoto, Masaru Iwai, Toshihiro Tanaka, Yusuke Nakamura, Wataru Kimura, Christine Bole-Feysot, Marthe Vilotte, Sylvie Odent, Jean-Luc Vilotte, Arnold Munnich, Alain Regnier, Nicolas Chassaing, Elfride De Baere, Isabelle Raymond-Letron, Josseline Kaplan, Patrick Calvas, Olivier Roche, Jean-Michel Rozet. Submicroscopic deletions at 13q32.1 cause congenital microcoria. Am. J. Hum. Genet. 2015.04; 96 (4): 631-639. ( PubMed, DOI )

Meian He, Min Xu, Ben Zhang, Jun Liang, Peng Chen, Jong-Young Lee, Todd A Johnson, Huaixing Li, Xiaobo Yang, Juncheng Dai, Liming Liang, Lixuan Gui, Qibin Qi, Jinyan Huang, Yanping Li, Linda S Adair, Tin Aung, Qiuyin Cai, Ching-Yu Cheng, Myeong-Chan Cho, Yoon Shin Cho, Minjie Chu, Bin Cui, Yu-Tang Gao, Min Jin Go, Dongfeng Gu, Weiqiong Gu, Huan Guo, Yongchen Hao, Jie Hong, Zhibin Hu, Yanling Hu, Jianfeng Huang, Joo-Yeon Hwang, Mohammad Kamran Ikram, Guangfu Jin, Dae-Hee Kang, Chiea Chuen Khor, Bong-Jo Kim, Hung Tae Kim, Michiaki Kubo, Jeannette Lee, Juyoung Lee, Nanette R Lee, Ruoying Li, Jun Li, JianJun Liu, Jirong Longe, Wei Lu, Xiangfeng Lu, Xiaoping Miao, Yukinori Okada, Rick Twee-Hee Ong, Gaokun Qiu, Mark Seielstad, Xueling Sim, Huaidong Song, Fumihiko Takeuchi, Toshihiro Tanaka, Phil R Taylor, Laiyuan Wang, Weiqing Wang, Yiqin Wang, Chen Wu, Ying Wu, Yong-Bing Xiang, Ken Yamamoto, Handong Yang, Ming Liao, Mitsuhiro Yokota, Terri Young, Xiaomin Zhang, Norihiro Kato, Qing K Wang, Wei Zheng, Frank B Hu, Dongxin Lin, Hongbing Shen, Yik Ying Teo, Zengnan Mo, Tien Yin Wong, Xu Lin, Karen L Mohlke, Guang Ning, Tatsuhiko Tsunoda, Bok-Ghee Han, Xiao-Ou Shu, E Shyong Tai, Tangchun Wu, Lu Qi. Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci. Hum. Mol. Genet. 2015.03; 24 (6): 1791-1800. ( PubMed, DOI )

Adam E Locke, Bratati Kahali, Sonja I Berndt, Anne E Justice, Tune H Pers, Felix R Day, Corey Powell, Sailaja Vedantam, Martin L Buchkovich, Jian Yang, Damien C Croteau-Chonka, Tonu Esko, Tove Fall, Teresa Ferreira, Stefan Gustafsson, Zoltán Kutalik, Jian'an Luan, Reedik Mägi, Joshua C Randall, Thomas W Winkler, Andrew R Wood, Tsegaselassie Workalemahu, Jessica D Faul, Jennifer A Smith, Jing Hua Zhao, Wei Zhao, Jin Chen, Rudolf Fehrmann, Åsa K Hedman, Juha Karjalainen, Ellen M Schmidt, Devin Absher, Najaf Amin, Denise Anderson, Marian Beekman, Jennifer L Bolton, Jennifer L Bragg-Gresham, Steven Buyske, Ayse Demirkan, Guohong Deng, Georg B Ehret, Bjarke Feenstra, Mary F Feitosa, Krista Fischer, Anuj Goel, Jian Gong, Anne U Jackson, Stavroula Kanoni, Marcus E Kleber, Kati Kristiansson, Unhee Lim, Vaneet Lotay, Massimo Mangino, Irene Mateo Leach, Carolina Medina-Gomez, Sarah E Medland, Michael A Nalls, Cameron D Palmer, Dorota Pasko, Sonali Pechlivanis, Marjolein J Peters, Inga Prokopenko, Dmitry Shungin, Alena Stančáková, Rona J Strawbridge, Yun Ju Sung, Toshiko Tanaka, Alexander Teumer, Stella Trompet, Sander W van der Laan, Jessica van Setten, Jana V Van Vliet-Ostaptchouk, Zhaoming Wang, Loïc Yengo, Weihua Zhang, Aaron Isaacs, Eva Albrecht, Johan Ärnlöv, Gillian M Arscott, Antony P Attwood, Stefania Bandinelli, Amy Barrett, Isabelita N Bas, Claire Bellis, Amanda J Bennett, Christian Berne, Roza Blagieva, Matthias Blüher, Stefan Böhringer, Lori L Bonnycastle, Yvonne Böttcher, Heather A Boyd, Marcel Bruinenberg, Ida H Caspersen, Yii-Der Ida Chen, Robert Clarke, E Warwick Daw, Anton J M de Craen, Graciela Delgado, Maria Dimitriou, Alex S F Doney, Niina Eklund, Karol Estrada, Elodie Eury, Lasse Folkersen, Ross M Fraser, Melissa E Garcia, Frank Geller, Vilmantas Giedraitis, Bruna Gigante, Alan S Go, Alain Golay, Alison H Goodall, Scott D Gordon, Mathias Gorski, Hans-Jörgen Grabe, Harald Grallert, Tanja B Grammer, Jürgen Gräßler, Henrik Grönberg, Christopher J Groves, Gaëlle Gusto, Jeffrey Haessler, Per Hall, Toomas Haller, Goran Hallmans, Catharina A Hartman, Maija Hassinen, Caroline Hayward, Nancy L Heard-Costa, Quinta Helmer, Christian Hengstenberg, Oddgeir Holmen, Jouke-Jan Hottenga, Alan L James, Janina M Jeff, Åsa Johansson, Jennifer Jolley, Thorhildur Juliusdottir, Leena Kinnunen, Wolfgang Koenig, Markku Koskenvuo, Wolfgang Kratzer, Jaana Laitinen, Claudia Lamina, Karin Leander, Nanette R Lee, Peter Lichtner, Lars Lind, Jaana Lindström, Ken Sin Lo, Stéphane Lobbens, Roberto Lorbeer, Yingchang Lu, François Mach, Patrik K E Magnusson, Anubha Mahajan, Wendy L McArdle, Stela McLachlan, Cristina Menni, Sigrun Merger, Evelin Mihailov, Lili Milani, Alireza Moayyeri, Keri L Monda, Mario A Morken, Antonella Mulas, Gabriele Müller, Martina Müller-Nurasyid, Arthur W Musk, Ramaiah Nagaraja, Markus M Nöthen, Ilja M Nolte, Stefan Pilz, Nigel W Rayner, Frida Renstrom, Rainer Rettig, Janina S Ried, Stephan Ripke, Neil R Robertson, Lynda M Rose, Serena Sanna, Hubert Scharnagl, Salome Scholtens, Fredrick R Schumacher, William R Scott, Thomas Seufferlein, Jianxin Shi, Albert Vernon Smith, Joanna Smolonska, Alice V Stanton, Valgerdur Steinthorsdottir, Kathleen Stirrups, Heather M Stringham, Johan Sundström, Morris A Swertz, Amy J Swift, Ann-Christine Syvänen, Sian-Tsung Tan, Bamidele O Tayo, Barbara Thorand, Gudmar Thorleifsson, Jonathan P Tyrer, Hae-Won Uh, Liesbeth Vandenput, Frank C Verhulst, Sita H Vermeulen, Niek Verweij, Judith M Vonk, Lindsay L Waite, Helen R Warren, Dawn Waterworth, Michael N Weedon, Lynne R Wilkens, Christina Willenborg, Tom Wilsgaard, Mary K Wojczynski, Andrew Wong, Alan F Wright, Qunyuan Zhang ; LifeLines Cohort Study, Eoin P Brennan, Murim Choi, Zari Dastani, Alexander W Drong, Per Eriksson, Anders Franco-Cereceda, Jesper R Gådin, Ali G Gharavi, Michael E Goddard, Robert E Handsaker, Jinyan Huang, Fredrik Karpe, Sekar Kathiresan, Sarah Keildson, Krzysztof Kiryluk, Michiaki Kubo, Jong-Young Lee, Liming Liang, Richard P Lifton, Baoshan Ma, Steven A McCarroll, Amy J McKnight, Josine L Min, Miriam F Moffatt, Grant W Montgomery, Joanne M Murabito, George Nicholson, Dale R Nyholt, Yukinori Okada, John R B Perry, Rajkumar Dorajoo, Eva Reinmaa, Rany M Salem, Niina Sandholm, Robert A Scott, Lisette Stolk, Atsushi Takahashi, Toshihiro Tanaka, Ferdinand M Van't Hooft, Anna A E Vinkhuyzen, Harm-Jan Westra, Wei Zheng, Krina T Zondervan; ADIPOGen Consortium ; AGEN-BMI Working Group ; CARDIOGRAMplusC4D Consortium ; CKDGen Consortium ; GLGC ; ICBP; MAGIC Investigators ; MuTHER Consortium; MlGen Consortium ; PAGE Consortium ; ReproGen Consortium; GENIE Consortium; International Endogene Consortium , Andrew C Heath, Dominique Arveiler, Stephan J L Bakker, John Beilby, Richard N Bergman, John Blangero, Pascal Bovet, Harry Campbell, Mark J Caulfield, Giancarlo Cesana, Aravinda Chakravarti, Daniel I Chasman, Peter S Chines, Francis S Collins, Dana C Crawford, L Adrienne Cupples, Daniele Cusi, John Danesh, Ulf de Faire, Hester M den Ruijter, Anna F Dominiczak, Raimund Erbel, Jeanette Erdmann, Johan G Eriksson, Martin Farrall, Stephan B Felix, Ele Ferrannini, Jean Ferrières, Ian Ford, Nita G Forouhi, Terrence Forrester, Oscar H Franco, Ron T Gansevoort, Pablo V Gejman, Christian Gieger, Omri Gottesman, Vilmundur Gudnason, Ulf Gyllensten, Alistair S Hall, Tamara B Harris, Andrew T Hattersley, Andrew A Hicks, Lucia A Hindorff, Aroon D Hingorani, Albert Hofman, Georg Homuth, G Kees Hovingh, Steve E Humphries, Steven C Hunt, Elina Hyppönen, Thomas Illig, Kevin B Jacobs, Marjo-Riitta Jarvelin, Karl-Heinz Jöckel, Berit Johansen, Pekka Jousilahti, J Wouter Jukema, Antti M Jula, Jaakko Kaprio, John J P Kastelein, Sirkka M Keinanen-Kiukaanniemi, Lambertus A Kiemeney, Paul Knekt, Jaspal S Kooner, Charles Kooperberg, Peter Kovacs, Aldi T Kraja, Meena Kumari, Johanna Kuusisto, Timo A Lakka, Claudia Langenberg, Loic Le Marchand, Terho Lehtimäki, Valeriya Lyssenko, Satu Männistö, André Marette, Tara C Matise, Colin A McKenzie, Barbara McKnight, Frans L Moll, Andrew D Morris, Andrew P Morris, Jeffrey C Murray, Mari Nelis, Claes Ohlsson, Albertine J Oldehinkel, Ken K Ong, Pamela A F Madden, Gerard Pasterkamp, John F Peden, Annette Peters, Dirkje S Postma, Peter P Pramstaller, Jackie F Price, Lu Qi, Olli T Raitakari, Tuomo Rankinen, D C Rao, Treva K Rice, Paul M Ridker, John D Rioux, Marylyn D Ritchie, Igor Rudan, Veikko Salomaa, Nilesh J Samani, Jouko Saramies, Mark A Sarzynski, Heribert Schunkert, Peter E H Schwarz, Peter Sever, Alan R Shuldiner, Juha Sinisalo, Ronald P Stolk, Konstantin Strauch, Anke Tönjes, David-Alexandre Trégouët, Angelo Tremblay, Elena Tremoli, Jarmo Virtamo, Marie-Claude Vohl, Uwe Völker, Gérard Waeber, Gonneke Willemsen, Jacqueline C Witteman, M Carola Zillikens, Linda S Adair, Philippe Amouyel, Folkert W Asselbergs, Themistocles L Assimes, Murielle Bochud, Bernhard O Boehm, Eric Boerwinkle, Stefan R Bornstein, Erwin P Bottinger, Claude Bouchard, Stéphane Cauchi, John C Chambers, Stephen J Chanock, Richard S Cooper, Paul I W de Bakker, George Dedoussis, Luigi Ferrucci, Paul W Franks, Philippe Froguel, Leif C Groop, Christopher A Haiman, Anders Hamsten, Jennie Hui, David J Hunter, Kristian Hveem, Robert C Kaplan, Mika Kivimaki, Diana Kuh, Markku Laakso, Yongmei Liu, Nicholas G Martin, Winfried März, Mads Melbye, Andres Metspalu, Susanne Moebus, Patricia B Munroe, Inger Njølstad, Ben A Oostra, Colin N A Palmer, Nancy L Pedersen, Markus Perola, Louis Pérusse, Ulrike Peters, Chris Power, Thomas Quertermous, Rainer Rauramaa, Fernando Rivadeneira, Timo E Saaristo, Danish Saleheen, Naveed Sattar, Eric E Schadt, David Schlessinger, P Eline Slagboom, Harold Snieder, Tim D Spector, Unnur Thorsteinsdottir, Michael Stumvoll, Jaakko Tuomilehto, André G Uitterlinden, Matti Uusitupa, Pim van der Harst, Mark Walker, Henri Wallaschofski, Nicholas J Wareham, Hugh Watkins, David R Weir, H-Erich Wichmann, James F Wilson, Pieter Zanen, Ingrid B Borecki, Panos Deloukas, Caroline S Fox, Iris M Heid, Jeffrey R O'Connell, David P Strachan, Kari Stefansson, Cornelia M van Duijn, Gonçalo R Abecasis, Lude Franke, Timothy M Frayling, Mark I McCarthy, Peter M Visscher, André Scherag, Cristen J Willer, Michael Boehnke, Karen L Mohlke, Cecilia M Lindgren, Jacques S Beckmann, Inês Barroso, Kari E North, Erik Ingelsson, Joel N Hirschhorn, Ruth J F Loos, Elizabeth K Speliotes. Genetic studies of body mass index yield new insights for obesity biology. Nature. 2015.02; 518 (7538): 197-206. ( PubMed, DOI )

Shigemizu D, Aiba T, Nakagawa H, Ozaki K, Miya F, Satake W, Toda T, Miyamoto Y, Fujimoto A, Suzuki Y, Kubo M, Tsunoda T, Shimizu W, and Tanaka T . Exome analyses of long QT syndrome reveal candidate pathogenic mutations in calmodulin-interacting genes PLoS One . 2015;

Matsukura Mitsuru, Ozaki Kouichi, Takahashi Atsushi, Onouchi Yoshihiro, Morizono Takashi, Komai Hiroyoshi, Shigematsu Hiroshi, Kudo Toshifumi, Inoue Yoshinori, Kimura Hideo, Hosaka Akihiro, Shigematsu Kunihiro, Miyata Teturo, Watanabe Toshiaki, Tsunoda Tatsuhiko, Kubo Michiaki, Tanaka Toshihiro. Genome-Wide Association Study of Peripheral Arterial Disease in a Japanese Population. PLoS One. 2015; 10 (10): e0139262. ( PubMed, DOI )

Wen W, Zheng W, Okada Y, Takeuchi F, Tabara Y, Hwang JY, Dorajoo R, Li H, Tsai FJ, Yang X, He J, Wu Y, He M, Zhang Y, Liang J, Guo X, Sheu WH, Delahanty R, Guo X, Kubo M, Yamamoto K, Ohkubo T, Go MJ, Liu JJ, Gan W, Chen CC, Gao Y, Li S, Lee NR, Wu C, Zhou X, Song H, Yao J, Lee IT, Long J, Tsunoda T, Akiyama K, Takashima N, Cho YS, Ong RT, Lu L, Chen CH, Tan A, Rice TK, Adair LS, Gui L, Allison M, Lee WJ, Cai Q, Isomura M, Umemura S, Kim YJ, Seielstad M, Hixson J, Xiang YB, Isono M, Kim BJ, Sim X, Lu W, Nabika T, Lee J, Lim WY, Gao YT, Takayanagi R, Kang DH, Wong TY, Hsiung CA, Wu IC, Juang JM, Shi J, Choi BY, Aung T, Hu F, Kim MK, Lim WY, Wang TD, Shin MH, Lee J, Ji BT, Lee YH, Young TL, Shin DH, Chun BY, Cho MC, Han BG, Hwu CM, Assimes TL, Absher D, Yan X, Kim E, Kuo JZ, Kwon S, Taylor KD, Chen YD, Rotter JI, Qi L, Zhu D, Wu T, Mohlke KL, Gu D, Mo Z, Wu JY, Lin X, Miki T, Tai ES, Lee JY, Kato N, Shu XO, Tanaka T. Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index. Hum Mol Genet. 2014.10; 23 (20): 5492-5504. ( PubMed, DOI )

Fukuda M, Mizutani T, Mochizuki W, Matsumoto T, Nozaki K, Sakamaki Y, Ichinose S, Okada Y, Tanaka T, Watanabe M, Nakamura T. Small intestinal stem cell identity is maintained with functional Paneth cells in heterotopically grafted epithelium onto the colon. Genes Dev. 2014.08; 28 (16): 1752-1757. ( PubMed, DOI )

Hara M, Sakata Y, Nakatani D, Shinichiro Suna S, Usami M, Matsumoto S, Ozaki K, Nishino M, Sato H, Kitamura T, Nanto S, Hamasaki T, Tanaka T, Hori M, Komuro I. Reduced risk of recurrent myocardial infarction in homozygous carriers of the chromosome 9p21 rs1333049 C risk allele in the contemporary percutaneous coronary intervention era: a prospective observational study. BMJ Open. 2014.08; 4 (8): e005438.

Kolek MJ, Edwards TL, Muhammad R, Balouch A, Shoemaker MB, Blair MA, Kor KC, Takahashi A, Kubo M, Roden DM, Tanaka T, Darbar D. A genome-wide association study to identify genomic modulators of rate control therapy in patients with atrial fibrillation. Am J Cardiol. 2014.08; 114 (4): 593-600. ( PubMed, DOI )

Sinner MF, Tucker NR, Lunetta KL, Ozaki K, Smith JG, Trompet S, Bis JC, Lin H, Chung MK, Nielsen JB, Lubitz SA, Krijthe BP, Magnani JW, Ye J, Gollob MH, Tsunoda T, Müller-Nurasyid M, Lichtner P, Peters A, Dolmatova E, Kubo M, Smith JD, Psaty BM, Smith NL, Jukema JW, Chasman DI, Albert CM, Ebana Y, Furukawa T, Macfarlane PW, Harris TB, Darbar D, Dörr M, Holst AG, Svendsen JH, Hofman A, Uitterlinden AG, Gudnason V, Isobe M, Malik R, Dichgans M, Rosand J, Van Wagoner DR; METASTROKE Consortium; AFGen Consortium, Benjamin EJ, Milan DJ, Melander O, Heckbert SR, Ford I, Liu Y, Barnard J, Olesen MS, Stricker BH, Tanaka T, Kääb S, Ellinor PT.. Integrating Genetic, Transcriptional, and Functional Analyses to Identify Five Novel Genes for Atrial Fibrillation. Circulation. 2014.08; ( PubMed, DOI )

Makita N, Yagihara N, Crotti L, Johnson CN, Beckmann BM, Roh MS, Shigemizu D, Lichtner P, Ishikawa T, Aiba T, Homfray T, Behr ER, Klug D, Denjoy I,Mastantuono E, Theisen D, Tsunoda T, Satake W, Toda T, Nakagawa H, Tsuji Y, Tsuchiya T, Yamamoto H, Miyamoto Y, Endo N, Kimura A, Ozaki K, Motomura H, Suda K, Tanaka T, Schwartz PJ, Meitinger T, Kääb S, Guicheney P, Shimizu W, Bhuiyan ZA, Watanabe H, Chazin WJ, George AL Jr. Novel calmodulin mutations associated with congenital arrhythmia susceptibility. Circ Cardiovasc Genet. 2014.08; 7 (4): 466-474. ( PubMed, DOI )

Chen P, Takeuchi F, Lee JY, Li H, Wu JY, Liang J, Long J, Tabara Y, Goodarzi M, Pereira MA, Kim YJ, Go MJ, Stram DO, Vithana E, Khor CC, Liu J, Liao J, Ye X, Wang Y, Lu L, Young TL, Lee J, Thai AC, Cheng CY, van Dam RM, Friedlander Y, Heng CK, Koh WP, Chen CH, Chang LC, Pan WH, Qi Q, Isono M, Zheng W, Cai Q, Gao Y, Yamamoto K, Ohnaka K, Takayanagi R, Kita Y, Ueshima H, Hsiung CA, Cui J, Sheu WH, Rotter JI, Chen YD, Hsu C, Okada Y, Kubo M, Takahashi A, Tanaka T, van Rooij FJ, Ganesh SK, Huang J, Huang T, Yuan J, Hwang JY; CHARGE Hematology Working Group, Gross MD, Assimes TL, Miki T, Shu XO, Qi L, Chen YT, Lin X, Aung T, Wong TY, Teo YY, Kim BJ, Kato N, Tai ES.. Multiple nonglycemic genomic loci are newly associated with blood level of glycated hemoglobin in East Asians. Diabetes. 2014.07; 63 (7): 2551-2562. ( PubMed, DOI )

Hirokawa M, Morita H, Tajima T, Takahashi A, Ashikawa K, Miya F, Shigemizu D, Ozaki K, Sakata Y, Nakatani D, Suna S, Imai Y, Tanaka T, Tsunoda T, Matsuda K, Kadowaki T, Nakamura Y, Nagai R, Komuro I, Kubo M. A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese. Eur J Hum Genet. 2014.06; ( PubMed, DOI )

Hara M, Sakata Y, Nakatani D, Suna S, Usami M, Matsumoto S, Sugitani T, Ozaki K, Nishino M, Sato H, Kitamura T, Nanto S, Hamasaki T, Tanaka T, Hori M, Komuro I. Renin-angiotensin-aldosterone system polymorphisms and 5-year mortality in survivors of acute myocardial infarction: a report from the Osaka Acute Coronary Insufficiency Study. International Heart Journal. 2014.05; 55 190-196.

Lubitz SA, Lunetta KL, Lin H, Arking DE, Trompet S, Li G, Krijthe BP, Chasman DI, Barnard J, Kleber ME, Dörr M, Ozaki K, Smith AV, Müller M, Walter S, Agarwal SK, Bis JC, Brody JA, Chen LY, Everett BM, Ford I, Franco OH, Harris TB, Hofman A, Kääb S, Mahida S, Kathiresan S, Kubo M, Launer LJ, MacFarlane PW, Magnani JW, McKnight B, McManus DD, Peters A, Psaty BM, Rose LM, Rotter JI, Silbernagel G, Smith JD, Sotoodehnia N, Stott DJ, Taylor K, Tomaschitz A,Tsunoda T, Uitterlinden AG, VanWagoner DR, Völker U, Völzke H, Murabito JM, Sinner MF, Gudnason V, Felix SB, März W, Chung M, Albert CM, Stricker BH, Tanaka T, Heckbert SR, Jukema JW, Alonso A, Benjamin EJ, Ellinor PT. Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese. J Am Coll Cardiol. 2014.04; 63 (12): 1200-1210. ( PubMed, DOI )

Behr ER, Ritchie MD, Tanaka T, Kääb S, Crawford DC, Nicoletti P, Floratos A, Sinner MF, Kannankeril PJ, AA. M. Wilde, Bezzina CR, Schulze-Bahr E, Zumhagen S, Guicheney P, Bishopric NH, Marshall V, Shakir S, Dalageorgou C, Bevan S, Jamshidi Y, Bastiaenen R, Myerberg RJ, Schott J-J, Camm AJ, Steinbeck G, Norris K, Altman RB, Tatonetti N, Jeffery S, Kubo M, Nakamura Y, Shen Y, George, Jr. AL.. Genome wide analysis of drug-induced Torsades de Pointes: lack of common variants with large effect sizes. PLoS One. 2013.11; 8 (11):

Suna S, Sakata Y, Nakatani D, Okuda K, Shimizu M, Usami M, Matsumoto S, Hara M, Ozaki K, Mizuno H, Minamino T, Takashima S, Nishino M, Matsumura Y, Takeda H, Tanaka T, Sato H, Hori M, Komuro I. Decreased mortality associated with statin treatment in patients with acute myocardial infarction and lymphotoxin-alpha C804A polymorphism. Atherosclerosis. 2013.04; 227 (2): 373-379. ( PubMed, DOI )

Onouchi Y, Suzuki Y, Suzuki H, Terai M, Yasukawa K, Hamada H, Suenaga T, Honda T, Honda A, Kobayashi H, Takeuchi T, Yoshikawa N, Sato J, Shibuta S, Miyawaki M, Oishi K, Yamaga H, Aoyagi N, Iwahashi S, Miyashita R, Murata Y, Ebata R, Higashi K, Ozaki K, Sasago K, Tanaka T, Hata A. ITPKC and CASP3 polymorphisms and risks for IVIG unresponsiveness and coronary artery lesion formation in Kawasaki disease. Pharmacogenomics J. 2013.02; 13 (1): 52-59. ( PubMed, DOI )

Kottgen A, Albrecht E, Teumer A, Vitart V, Krumsiek J, Hundertmark C, Pistis G, Ruggiero D, O'Seaghdha CM, Haller T, Yang Q, Tanaka T, Johnson AD, Kutalik Z, Smith AV, Shi J, Struchalin M, Middelberg RP, Brown MJ, Gaffo AL, Pirastu N, Li G, Hayward C, Zemunik T, Huffman J, Yengo L, Zhao JH, Demirkan A, Feitosa MF, Liu X, Malerba G, Lopez LM, van der Harst P, Li X, Kleber ME, Hicks AA, Nolte IM, Johansson A, Murgia F, Wild SH, Bakker SJ, Peden JF, Dehghan A, Steri M, Tenesa A, Lagou V, Salo P, Mangino M, Rose LM, Lehtimaki T, Woodward OM, Okada Y, Tin A, Muller C, Oldmeadow C, Putku M, Czamara D, Kraft P, Frogheri L, Thun GA, Grotevendt A, Gislason GK, Harris TB, Launer LJ, McArdle P, Shuldiner AR, Boerwinkle E, Coresh J, Schmidt H, Schallert M, Martin NG, Montgomery GW, Kubo M, Nakamura Y, Tanaka T, Munroe PB, Samani NJ, Jacobs DR Jr, Liu K, D'Adamo P, Ulivi S, Rotter JI, Psaty BM, Vollenweider P, Waeber G, Campbell S, Devuyst O, Navarro P, Kolcic I, Hastie N, Balkau B, Froguel P, Esko T, Salumets A, Khaw KT, Langenberg C, Wareham NJ, Isaacs A, Kraja A, Zhang Q, Wild PS, Scott RJ, Holliday EG, Org E, Viigimaa M, Bandinelli S, Metter JE, Lupo A, Trabetti E, Sorice R, Doring A, Lattka E, Strauch K, Theis F, Waldenberger M, Wichmann HE, Davies G, Gow AJ, Bruinenberg M, Stolk RP, Kooner JS, Zhang W, Winkelmann BR, Boehm BO, Lucae S, Penninx BW, Smit JH, Curhan G, Mudgal P, Plenge RM, Portas L, Persico I, Kirin M, Wilson JF, Mateo Leach I, van Gilst WH, Goel A, Ongen H, Hofman A, Rivadeneira F, Uitterlinden AG, Imboden M, von Eckardstein A, Cucca F, Nagaraja R, Piras MG, Nauck M, Schurmann C, Budde K, Ernst F, Farrington SM, Theodoratou E, Prokopenko I, Stumvoll M, Jula A, Perola M, Salomaa V, Shin SY, Spector TD, Sala C, Ridker PM, Kahonen M, Viikari J, Hengstenberg C, Nelson CP, Meschia JF, Nalls MA, Sharma P, Singleton AB, Kamatani N, Zeller T, Burnier M, Attia J, Laan M, Klopp N, Hillege HL, Kloiber S, Choi H, Pirastu M, Tore S, Probst-Hensch NM, Volzke H, Gudnason V, Parsa A, Schmidt R, Whitfield JB, Fornage M, Gasparini P, Siscovick DS, Polasek O, Campbell H, Rudan I, Bouatia-Naji N, Metspalu A, Loos RJ, van Duijn CM, Borecki IB, Ferrucci L, Gambaro G, Deary IJ, Wolffenbuttel BH, Chambers JC, Marz W, Pramstaller PP, Snieder H, Gyllensten U, Wright AF, Navis G, Watkins H, Witteman JC, Sanna S, Schipf S, Dunlop MG, Tonjes A, Ripatti S, Soranzo N, Toniolo D, Chasman DI, Raitakari O, Kao WH, Ciullo M, Fox CS, Caulfield M, Bochud M, Gieger C. Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nat Genet. 2013.02; 45 (2): 145-154. ( PubMed, DOI )

Franceschini N, van Rooij FJ, Prins BP, Feitosa MF, Karakas M, Eckfeldt JH, Folsom AR, Kopp J, Vaez A, Andrews JS, Baumert J, Boraska V, Broer L, Hayward C, Ngwa JS, Okada Y, Polasek O, Westra HJ, Wang YA, Del Greco M F, Glazer NL, Kapur K, Kema IP, Lopez LM, Schillert A, Smith AV, Winkler CA, Zgaga L, Bandinelli S, Bergmann S, Boban M, Bochud M, Chen YD, Davies G, Dehghan A, Ding J, Doering A, Durda JP, Ferrucci L, Franco OH, Franke L, Gunjaca G, Hofman A, Hsu FC, Kolcic I, Kraja A, Kubo M, Lackner KJ, Launer L, Loehr LR, Li G, Meisinger C, Nakamura Y, Schwienbacher C, Starr JM, Takahashi A, Torlak V, Uitterlinden AG, Vitart V, Waldenberger M, Wild PS, Kirin M, Zeller T, Zemunik T, Zhang Q, Ziegler A, Blankenberg S, Boerwinkle E, Borecki IB, Campbell H, Deary IJ, Frayling TM, Gieger C, Harris TB, Hicks AA, Koenig W, O' Donnell CJ, Fox CS, Pramstaller PP, Psaty BM, Reiner AP, Rotter JI, Rudan I, Snieder H, Tanaka T, van Duijn CM, Vollenweider P, Waeber G, Wilson JF, Witteman JC, Wolffenbuttel BH, Wright AF, Wu Q, Liu Y, Jenny NS, North KE, Felix JF, Alizadeh BZ, Cupples LA, Perry JR, Morris AP. Discovery and fine mapping of serum protein loci through transethnic meta-analysis. Am J Hum Genet. 2012.10; 91 (4): 744-753. ( PubMed, DOI )

Okada Y, Sim X, Go MJ, Wu JY, Gu D, Takeuchi F, Takahashi A, Maeda S, Tsunoda T, Chen P, Lim SC, Wong TY, Liu J, Young TL, Aung T, Seielstad M, Teo YY, Kim YJ, Lee JY, Han BG, Kang D, Chen CH, Tsai FJ, Chang LC, Fann SJ, Mei H, Rao DC, Hixson JE, Chen S, Katsuya T, Isono M, Ogihara T, Chambers JC, Zhang W, Kooner JS, Albrecht E, Yamamoto K, Kubo M, Nakamura Y, Kamatani N, Kato N, He J, Chen YT, Cho YS, Tai ES, Tanaka T. Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. Nat Genet. 2012.08; 44 (8): 904-909. ( PubMed, DOI )

Ellinor PT, Lunetta KL, Albert CM, Glazer NL, Ritchie MD, Smith AV, Arking DE, Muller-Nurasyid M, Krijthe BP, Lubitz SA, Bis JC, Chung MK, Dorr M, Ozaki K, Roberts JD, Smith JG, Pfeufer A, Sinner MF, Lohman K, Ding J, Smith NL, Smith JD, Rienstra M, Rice KM, Van Wagoner DR, Magnani JW, Wakili R, Clauss S, Rotter JI, Steinbeck G, Launer LJ, Davies RW, Borkovich M, Harris TB, Lin H, Volker U, Volzke H, Milan DJ, Hofman A, Boerwinkle E, Chen LY, Soliman EZ, Voight BF, Li G, Chakravarti A, Kubo M, Tedrow UB, Rose LM, Ridker PM, Conen D, Tsunoda T, Furukawa T, Sotoodehnia N, Xu S, Kamatani N, Levy D, Nakamura Y, Parvez B, Mahida S, Furie KL, Rosand J, Muhammad R, Psaty BM, Meitinger T, Perz S, Wichmann HE, Witteman JC, Kao WH, Kathiresan S, Roden DM, Uitterlinden AG, Rivadeneira F, McKnight B, Sjogren M, Newman AB, Liu Y, Gollob MH, Melander O, Tanaka T, Stricker BH, Felix SB, Alonso A, Darbar D, Barnard J, Chasman DI, Heckbert SR, Benjamin EJ, Gudnason V, Kaab S. Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nat Genet. 2012.06; 44 (6): 670-675. ( PubMed, DOI )

Onouchi Y, Ozaki K, Burns JC, Shimizu C, Terai M, Hamada H, Honda T, Suzuki H, Suenaga T, Takeuchi T, Yoshikawa N, Suzuki Y, Yasukawa K, Ebata R, Higashi K, Saji T, Kemmotsu Y, Takatsuki S, Ouchi K, Kishi F, Yoshikawa T, Nagai T, Hamamoto K, Sato Y, Honda A, Kobayashi H, Sato J, Shibuta S, Miyawaki M, Oishi K, Yamaga H, Aoyagi N, Iwahashi S, Miyashita R, Murata Y, Sasago K, Takahashi A, Kamatani N, Kubo M, Tsunoda T, Hata A, Nakamura Y, Tanaka T. A genome-wide association study identifies three new risk loci for Kawasaki disease. Nat Genet. 2012.05; 44 (5): 517-521. ( PubMed, DOI )

Okada Y, Kubo M, Ohmiya H, Takahashi A, Kumasaka N, Hosono N, Maeda S, Wen W, Dorajoo R, Go MJ, Zheng W, Kato N, Wu JY, Lu Q, Tsunoda T, Yamamoto K, Nakamura Y, Kamatani N, Tanaka T. Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations. Nat Genet. 2012.03; 44 (3): 302-306. ( PubMed, DOI )

Wen W, Cho YS, Zheng W, Dorajoo R, Kato N, Qi L, Chen CH, Delahanty RJ, Okada Y, Tabara Y, Gu D, Zhu D, Haiman CA, Mo Z, Gao YT, Saw SM, Go MJ, Takeuchi F, Chang LC, Kokubo Y, Liang J, Hao M, Le Marchand L, Zhang Y, Hu Y, Wong TY, Long J, Han BG, Kubo M, Yamamoto K, Su MH, Miki T, Henderson BE, Song H, Tan A, He J, Ng DP, Cai Q, Tsunoda T, Tsai FJ, Iwai N, Chen GK, Shi J, Xu J, Sim X, Xiang YB, Maeda S, Ong RT, Li C, Nakamura Y, Aung T, Kamatani N, Liu JJ, Lu W, Yokota M, Seielstad M, Fann CS, Wu JY, Lee JY, Hu FB, Tanaka T, Tai ES, Shu XO. Meta-analysis identifies common variants associated with body mass index in east Asians. Nat Genet. 2012.03; 44 (3): 307-311. ( PubMed, DOI )

Clarke R, Bennett DA, Parish S, Verhoef P, Dötsch-Klerk M, Lathrop M, Xu P, Nordestgaard BG, Holm H, Hopewell JC, Saleheen D, Tanaka T, Anand SS, Chambers JC, Kleber ME, Ouwehand WH, Yamada Y, Elbers C, Peters B, Stewart AF, Reilly MM, Thorand B, Yusuf S, Engert JC, Assimes TL, Kooner J, Danesh J, Watkins H, Samani NJ, Collins R, Peto R,. Homocysteine and coronary heart disease: meta-analysis of MTHFR case-control studies, avoiding publication bias. PLoS Med. 2012.02; 9 (2): e1001177. ( PubMed, DOI )

Kumasaka N, Aoki M, Okada Y, Takahashi A, Ozaki K, Mushiroda T, Hirota T, Tamari M, Tanaka T, Nakamura Y, Kamatani N, Kubo M. Haplotypes with copy number and single nucleotide polymorphisms in CYP2A6 locus are associated with smoking quantity in a Japanese population. PLoS One. 2012; 7 (9): e44507. ( PubMed, DOI )

Kim YJ, Go MJ, Hu C, Hong CB, Kim YK, Lee JY, Hwang JY, Oh JH, Kim DJ, Kim NH, Kim S, Hong EJ, Kim JH, Min H, Kim Y, Zhang R, Jia W, Okada Y, Takahashi A, Kubo M, Tanaka T, Kamatani N, Matsuda K, Park T, Oh B, Kimm K, Kang D, Shin C, Cho NH, Kim HL, Han BG, Lee JY, Cho YS. Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits. Nat Genet. 2011.10; 43 (10): 990-995. ( PubMed, DOI )

Iida A, Takahashi A, Kubo M, Saito S, Hosono N, Ohnishi Y, Kiyotani K, Mushiroda T, Nakajima M, Ozaki K, Tanaka T, Tsunoda T, Oshima S, Sano M, Kamei T, Tokuda T, Aoki M, Hasegawa K, Mizoguchi K, Morita M, Takahashi Y, Katsuno M, Atsuta N, Watanabe H, Tanaka F, Kaji R, Nakano I, Kamatani N, Tsuji S, Sobue G, Nakamura Y, Ikegawa S. A functional variant in ZNF512B is associated with susceptibility to amyotrophic lateral sclerosis in Japanese. Hum Mol Genet. 2011.09; 20 (18): 3684-3692. ( PubMed, DOI )

Liao YC, Wang YS, Guo YC, Ozaki K, Tanaka T, Lin HF, Chang MH, Chen KC, Yu ML, Sheu SH, Juo SH. BRAP Activates Inflammatory Cascades and Increases the Risk for Carotid Atherosclerosis. Mol Med. 2011.09; 17 (9-10): 1065-1074. ( PubMed, DOI )

Okada Y, Hirota T, Kamatani Y, Takahashi A, Ohmiya H, Kumasaka N, Higasa K, Yamaguchi-Kabata Y, Hosono N, Nalls MA, Chen MH, van Rooij FJ, Smith AV, Tanaka T, Couper DJ, Zakai NA, Ferrucci L, Longo DL, Hernandez DG, Witteman JC, Harris TB, O'Donnell CJ, Ganesh SK, Matsuda K, Tsunoda T, Tanaka T, Kubo M, Nakamura Y, Tamari M, Yamamoto K, Kamatani N. Identification of nine novel loci associated with white blood cell subtypes in a Japanese population. PLoS Genet. 2011.06; 7 (6): e1002067. ( PubMed, DOI )

Nalls MA, Couper DJ, Tanaka T, van Rooij FJ, Chen MH, Smith AV, Toniolo D, Zakai NA, Yang Q, Greinacher A, Wood AR, Garcia M, Gasparini P, Liu Y, Lumley T, Folsom AR, Reiner AP, Gieger C, Lagou V, Felix JF, Volzke H, Gouskova NA, Biffi A, Doring A, Volker U, Chong S, Wiggins KL, Rendon A, Dehghan A, Moore M, Taylor K, Wilson JG, Lettre G, Hofman A, Bis JC, Pirastu N, Fox CS, Meisinger C, Sambrook J, Arepalli S, Nauck M, Prokisch H, Stephens J, Glazer NL, Cupples LA, Okada Y, Takahashi A, Kamatani Y, Matsuda K, Tsunoda T, Tanaka T, Kubo M, Nakamura Y, Yamamoto K, Kamatani N, Stumvoll M, Tonjes A, Prokopenko I, Illig T, Patel KV, Garner SF, Kuhnel B, Mangino M, Oostra BA, Thein SL, Coresh J, Wichmann HE, Menzel S, Lin J, Pistis G, Uitterlinden AG, Spector TD, Teumer A, Eiriksdottir G, Gudnason V, Bandinelli S, Frayling TM, Chakravarti A, van Duijn CM, Melzer D, Ouwehand WH, Levy D, Boerwinkle E, Singleton AB, Hernandez DG, Longo DL, Soranzo N, Witteman JC, Psaty BM, Ferrucci L, Harris TB, O'Donnell CJ, Ganesh SK. Multiple loci are associated with white blood cell phenotypes. PLoS Genet. 2011.06; 7 (6): e1002113. ( PubMed, DOI )

Okada Y, Takahashi A, Ohmiya H, Kumasaka N, Kamatani Y, Hosono N, Tsunoda T, Matsuda K, Tanaka T, Kubo M, Nakamura Y, Yamamoto K, Kamatani N. Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus. Hum Mol Genet. 2011.03; 20 (6): 1224-1231. ( PubMed, DOI )

Aoki A, Ozaki K, Sato H, Takahashi A, Kubo M, Sakata Y, Onouchi Y, Kawaguchi T, Lin TH, Takano H, Yasutake M, Hsu PC, Ikegawa S, Kamatani N, Tsunoda T, Juo SH, Hori M, Komuro I, Mizuno K, Nakamura Y, Tanaka T. SNPs on chromosome 5p15.3 associated with myocardial infarction in Japanese population. J Hum Genet. 2011.01; 56 (1): 47-51. ( PubMed, DOI )

Kou I, Takahashi A, Urano T, Fukui N, Ito H, Ozaki K, Tanaka T, Hosoi T, Shiraki M, Inoue S, Nakamura Y, Kamatani N, Kubo M, Mori S, Ikegawa S. Common variants in a novel gene, FONG on chromosome 2q33.1 confer risk of osteoporosis in Japanese. PLoS One. 2011; 6 (5): e19641. ( PubMed, DOI )

Onouchi Y, Ozaki K, Buns JC, Shimizu C, Hamada H, Honda T, Terai M, Honda A, Takeuchi T, Shibuta S, Suenaga T, Suzuki H, Higashi K, Yasukawa K, Suzuki Y, Sasago K, Kemmotsu Y, Takatsuki S, Saji T, Yoshikawa T, Nagai T, Hamamoto K, Kishi F, Ouchi K, Sato Y, Newburger JW, Baker AL, Shulman ST, Rowley AH, Yashiro M, Nakamura Y, Wakui K, Fukushima Y, Fujino A, Tsunoda T, Kawasaki T, Hata A, Nakamura Y, Tanaka T. Common variants in CASP3 confer susceptibility to Kawasaki disease. Hum Mol Genet. 2010.07; 19 (14): 2898-2906. ( PubMed, DOI )

Oishi Y, Manabe I, Imai Y, Hara K, Horikoshi M, Fujiu K, Tanaka T, Aizawa T, Kadowaki T, Nagai R. Regulatory polymorphism in transcription factor KLF5 at the MEF2 element alters the response to angiotensin II and is associated with human hypertension. FASEB J. 2010.06; 24 (6): 1780-1788. ( PubMed, DOI )

Takahashi H, Nakajima M, Ozaki K, Tanaka T, Kamatani N, Ikegawa S. Prediction model for knee osteoarthritis based on genetic and clinical information. Arthritis Res Ther. 2010; 12 (5): R187. ( PubMed, DOI )

, Birney E, Hudson TJ, Green ED, Gunter C, Eddy S, Rogers J, Harris JR, Ehrlich SD, Apweiler R, Austin CP, Berglund L, Bobrow M, Bountra C, Brookes AJ, Cambon-Thomsen A, Carter NP, Chisholm RL, Contreras JL, Cooke RM, Crosby WL, Dewar K, Durbin R, Dyke SO, Ecker JR, El Emam K, Feuk L, Gabriel SB, Gallacher J, Gelbart WM, Granell A, Guarner F, Hubbard T, Jackson SA, Jennings JL, Joly Y, Jones SM, Kaye J, Kennedy KL, Knoppers BM, Kyrpides NC, Lowrance WW, Luo J, MacKay JJ, Martín-Rivera L, McCombie WR, McPherson JD, Miller L, Miller W, Moerman D, Mooser V, Morton CC, Ostell JM, Ouellette BF, Parkhill J, Raina PS, Rawlings C, Scherer SE, Scherer SW, Schofield PN, Sensen CW, Stodden VC, Sussman MR, Tanaka T, Thornton J, Tsunoda T, Valle D, Vuorio EI, Walker NM, Wallace S, Weinstock G, Whitman WB, Worley KC, Wu C, Wu J, Yu J. Prepublication data sharing. Nature. 2009.09; 461 (7261): 168-170. ( PubMed, DOI )

Kaput J, Cotton RG, Hardman L, Watson M, Al Aqeel AI, Al-Aama JY, Al-Mulla F, Alonso S, Aretz S, Auerbach AD, Bapat B, Bernstein IT, Bhak J, Bleoo SL, Blöcker H, Brenner SE, Burn J, Bustamante M, Calzone R, Cambon-Thomsen A, Cargill M, Carrera P, Cavedon L, Cho YS, Chung YJ, Claustres M, Cutting G, Dalgleish R, den Dunnen JT, Díaz C, Dobrowolski S, dos Santos MR, Ekong R, Flanagan SB, Flicek P, Furukawa Y, Genuardi M, Ghang H, Golubenko MV, Greenblatt MS, Hamosh A, Hancock JM, Hardison R, Harrison TM, Hoffmann R, Horaitis R, Howard HJ, Barash CI, Izagirre N, Jung J, Kojima T, Laradi S, Lee YS, Lee JY, Gil-da-Silva-Lopes VL, Macrae FA, Maglott D, Marafie MJ, Marsh SG, Matsubara Y, Messiaen LM, Möslein G, Netea MG, Norton ML, Oefner PJ, Oetting WS, O'Leary JC, de Ramirez AM, Paalman MH, Parboosingh J, Patrinos GP, Perozzi G, Phillips IR, Povey S, Prasad S, Qi M, Quin DJ, Ramesar RS, Richards CS, Savige J, Scheible DG, Scott RJ, Seminara D, Shephard EA, Sijmons RH, Smith TD, Sobrido MJ, Tanaka T, Tavtigian SV, Taylor GR, Teague J, Töpel T, Ullman-Cullere M, Utsunomiya J, van Kranen HJ, Vihinen M, Webb E, Weber TK, Yeager M, Yeom YI, Yim SH, Yoo HS,. Planning the human variome project: the Spain report. Hum Mutat. 2009.04; 30 (4): 496-510. ( PubMed, DOI )

Ozaki K, Sato H, Inoue K, Tsunoda T, Sakata Y, Mizuno H, Lin TH, Miyamoto Y, Aoki A, Onouchi Y, Sheu SH, Ikegawa S, Odashiro K, Nobuyoshi M, Juo SH, Hori M, Nakamura Y, Tanaka T. SNPs in BRAP associated with risk of myocardial infarction in Asian populations. Nat Genet. 2009.03; 41 (3): 329-333. ( PubMed, DOI )

Suna S, Sakata Y, Shimizu M, Nakatani D, Usami M, Matsumoto S, Mizuno H, Ozaki K, Takashima S, Takeda H, Tanaka T, Hori M, Sato H. Lymphotoxin-alpha3 mediates monocyte-endothelial interaction by TNFR I/NF-kappaB signaling. Biochem Biophys Res Commun. 2009.02; 379 (2): 374-378. ( PubMed, DOI )

Miyamoto Y, Shi D, Nakajima M, Ozaki K, Sudo A, Kotani A, Uchida A, Tanaka T, Fukui N, Tsunoda T, Takahashi A, Nakamura Y, Jiang Q, Ikegawa S. Common variants in DVWA on chromosome 3p24.3 are associated with susceptibility to knee osteoarthritis. Nat Genet. 2008.08; 40 (8): 994-998. ( PubMed, DOI )

Mototani H, Iida A, Nakajima M, Furuichi T, Miyamoto Y, Tsunoda T, Sudo A, Kotani A, Uchida A, Ozaki K, Tanaka Y, Nakamura Y, Tanaka T, Notoya K, Ikegawa S. A functional SNP in EDG2 increases susceptibility to knee osteoarthritis in Japanese. Hum Mol Genet. 2008.06; 17 (12): 1790-1797. ( PubMed, DOI )

Hirose Y, Chiba K, Karasugi T, Nakajima M, Kawaguchi Y, Mikami Y, Furuichi T, Mio F, Miyake A, Miyamoto T, Ozaki K, Takahashi A, Mizuta H, Kubo T, Kimura T, Tanaka T, Toyama Y, Ikegawa S. A functional polymorphism in THBS2 that affects alternative splicing and MMP binding is associated with lumbar-disc herniation. Am J Hum Genet. 2008.05; 82 (5): 1122-1129. ( PubMed, DOI )

Kato M, Miya F, Kanemura Y, Tanaka T, Nakamura Y, Tsunoda T. Recombination rates of genes expressed in human tissues. Hum Mol Genet. 2008.02; 17 (4): 577-586. ( PubMed, DOI )

Mio F, Chiba K, Hirose Y, Kawaguchi Y, Mikami Y, Oya T, Mori M, Kamata M, Matsumoto M, Ozaki K, Tanaka T, Takahashi A, Kubo T, Kimura T, Toyama Y, Ikegawa S. A functional polymorphism in COL11A1, which encodes the alpha 1 chain of type XI collagen, is associated with susceptibility to lumbar disc herniation. Am J Hum Genet. 2007.12; 81 (6): 1271-1277. ( PubMed, DOI )

Frazer KA, Ballinger DG, Cox DR, Hinds DA, Stuve LL, Gibbs RA, Belmont JW, Boudreau A, Hardenbol P, Leal SM, Pasternak S, Wheeler DA, Willis TD, Yu F, Yang H, Zeng C, Gao Y, Hu H, Hu W, Li C, Lin W, Liu S, Pan H, Tang X, Wang J, Wang W, Yu J, Zhang B, Zhang Q, Zhao H, Zhao H, Zhou J, Gabriel SB, Barry R, Blumenstiel B, Camargo A, Defelice M, Faggart M, Goyette M, Gupta S, Moore J, Nguyen H, Onofrio RC, Parkin M, Roy J, Stahl E, Winchester E, Ziaugra L, Altshuler D, Shen Y, Yao Z, Huang W, Chu X, He Y, Jin L, Liu Y, Shen Y, Sun W, Wang H, Wang Y, Wang Y, Xiong X, Xu L, Waye MM, Tsui SK, Xue H, Wong JT, Galver LM, Fan JB, Gunderson K, Murray SS, Oliphant AR, Chee MS, Montpetit A, Chagnon F, Ferretti V, Leboeuf M, Olivier JF, Phillips MS, Roumy S, Sallee C, Verner A, Hudson TJ, Kwok PY, Cai D, Koboldt DC, Miller RD, Pawlikowska L, Taillon-Miller P, Xiao M, Tsui LC, Mak W, Song YQ, Tam PK, Nakamura Y, Kawaguchi T, Kitamoto T, Morizono T, Nagashima A, Ohnishi Y, Sekine A, Tanaka T, Tsunoda T, Deloukas P, Bird CP, Delgado M, Dermitzakis ET, Gwilliam R, Hunt S, Morrison J, Powell D, Stranger BE, Whittaker P, Bentley DR, Daly MJ, de Bakker PI, Barrett J, Chretien YR, Maller J, McCarroll S, Patterson N, Pe'er I, Price A, Purcell S, Richter DJ, Sabeti P, Saxena R, Schaffner SF, Sham PC, Varilly P, Altshuler D, Stein LD, Krishnan L, Smith AV, Tello-Ruiz MK, Thorisson GA, Chakravarti A, Chen PE, Cutler DJ, Kashuk CS, Lin S, Abecasis GR, Guan W, Li Y, Munro HM, Qin ZS, Thomas DJ, McVean G, Auton A, Bottolo L, Cardin N, Eyheramendy S, Freeman C, Marchini J, Myers S, Spencer C, Stephens M, Donnelly P, Cardon LR, Clarke G, Evans DM, Morris AP, Weir BS, Tsunoda T, Mullikin JC, Sherry ST, Feolo M, Skol A, Zhang H, Zeng C, Zhao H, Matsuda I, Fukushima Y, Macer DR, Suda E, Rotimi CN, Adebamowo CA, Ajayi I, Aniagwu T, Marshall PA, Nkwodimmah C, Royal CD, Leppert MF, Dixon M, Peiffer A, Qiu R, Kent A, Kato K, Niikawa N, Adewole IF, Knoppers BM, Foster MW, Clayton EW, Watkin J, Gibbs RA, Belmont JW, Muzny D, Nazareth L, Sodergren E, Weinstock GM, Wheeler DA, Yakub I, Gabriel SB, Onofrio RC, Richter DJ, Ziaugra L, Birren BW, Daly MJ, Altshuler D, Wilson RK, Fulton LL, Rogers J, Burton J, Carter NP, Clee CM, Griffiths M, Jones MC, McLay K, Plumb RW, Ross MT, Sims SK, Willey DL, Chen Z, Han H, Kang L, Godbout M, Wallenburg JC, L'Archeveque P, Bellemare G, Saeki K, Wang H, An D, Fu H, Li Q, Wang Z, Wang R, Holden AL, Brooks LD, McEwen JE, Guyer MS, Wang VO, Peterson JL, Shi M, Spiegel J, Sung LM, Zacharia LF, Collins FS, Kennedy K, Jamieson R, Stewart J. A second generation human haplotype map of over 3.1 million SNPs. Nature. 2007.10; 449 (7164): 851-861. ( PubMed, DOI )

Sabeti PC, Varilly P, Fry B, Lohmueller J, Hostetter E, Cotsapas C, Xie X, Byrne EH, McCarroll SA, Gaudet R, Schaffner SF, Lander ES, Frazer KA, Ballinger DG, Cox DR, Hinds DA, Stuve LL, Gibbs RA, Belmont JW, Boudreau A, Hardenbol P, Leal SM, Pasternak S, Wheeler DA, Willis TD, Yu F, Yang H, Zeng C, Gao Y, Hu H, Hu W, Li C, Lin W, Liu S, Pan H, Tang X, Wang J, Wang W, Yu J, Zhang B, Zhang Q, Zhao H, Zhao H, Zhou J, Gabriel SB, Barry R, Blumenstiel B, Camargo A, Defelice M, Faggart M, Goyette M, Gupta S, Moore J, Nguyen H, Onofrio RC, Parkin M, Roy J, Stahl E, Winchester E, Ziaugra L, Altshuler D, Shen Y, Yao Z, Huang W, Chu X, He Y, Jin L, Liu Y, Shen Y, Sun W, Wang H, Wang Y, Wang Y, Xiong X, Xu L, Waye MM, Tsui SK, Xue H, Wong JT, Galver LM, Fan JB, Gunderson K, Murray SS, Oliphant AR, Chee MS, Montpetit A, Chagnon F, Ferretti V, Leboeuf M, Olivier JF, Phillips MS, Roumy S, Sallee C, Verner A, Hudson TJ, Kwok PY, Cai D, Koboldt DC, Miller RD, Pawlikowska L, Taillon-Miller P, Xiao M, Tsui LC, Mak W, Song YQ, Tam PK, Nakamura Y, Kawaguchi T, Kitamoto T, Morizono T, Nagashima A, Ohnishi Y, Sekine A, Tanaka T, Tsunoda T, Deloukas P, Bird CP, Delgado M, Dermitzakis ET, Gwilliam R, Hunt S, Morrison J, Powell D, Stranger BE, Whittaker P, Bentley DR, Daly MJ, de Bakker PI, Barrett J, Chretien YR, Maller J, McCarroll S, Patterson N, Pe'er I, Price A, Purcell S, Richter DJ, Sabeti P, Saxena R, Schaffner SF, Sham PC, Varilly P, Altshuler D, Stein LD, Krishnan L, Smith AV, Tello-Ruiz MK, Thorisson GA, Chakravarti A, Chen PE, Cutler DJ, Kashuk CS, Lin S, Abecasis GR, Guan W, Li Y, Munro HM, Qin ZS, Thomas DJ, McVean G, Auton A, Bottolo L, Cardin N, Eyheramendy S, Freeman C, Marchini J, Myers S, Spencer C, Stephens M, Donnelly P, Cardon LR, Clarke G, Evans DM, Morris AP, Weir BS, Tsunoda T, Johnson TA, Mullikin JC, Sherry ST, Feolo M, Skol A, Zhang H, Zeng C, Zhao H, Matsuda I, Fukushima Y, Macer DR, Suda E, Rotimi CN, Adebamowo CA, Ajayi I, Aniagwu T, Marshall PA, Nkwodimmah C, Royal CD, Leppert MF, Dixon M, Peiffer A, Qiu R, Kent A, Kato K, Niikawa N, Adewole IF, Knoppers BM, Foster MW, Clayton EW, Watkin J, Gibbs RA, Belmont JW, Muzny D, Nazareth L, Sodergren E, Weinstock GM, Wheeler DA, Yakub I, Gabriel SB, Onofrio RC, Richter DJ, Ziaugra L, Birren BW, Daly MJ, Altshuler D, Wilson RK, Fulton LL, Rogers J, Burton J, Carter NP, Clee CM, Griffiths M, Jones MC, McLay K, Plumb RW, Ross MT, Sims SK, Willey DL, Chen Z, Han H, Kang L, Godbout M, Wallenburg JC, L'Archeveque P, Bellemare G, Saeki K, Wang H, An D, Fu H, Li Q, Wang Z, Wang R, Holden AL, Brooks LD, McEwen JE, Guyer MS, Wang VO, Peterson JL, Shi M, Spiegel J, Sung LM, Zacharia LF, Collins FS, Kennedy K, Jamieson R, Stewart J. Genome-wide detection and characterization of positive selection in human populations. Nature. 2007.10; 449 (7164): 913-918. ( PubMed, DOI )

Miyamoto Y, Mabuchi A, Shi D, Kubo T, Takatori Y, Saito S, Fujioka M, Sudo A, Uchida A, Yamamoto S, Ozaki K, Takigawa M, Tanaka T, Nakamura Y, Jiang Q, Ikegawa S. A functional polymorphism in the 5' UTR of GDF5 is associated with susceptibility to osteoarthritis. Nat Genet. 2007.04; 39 (4): 529-533. ( PubMed, DOI )

Ebana Y, Ozaki K, Inoue K, Sato H, Iida A, Lwin H, Saito S, Mizuno H, Takahashi A, Nakamura T, Miyamoto Y, Ikegawa S, Odashiro K, Nobuyoshi M, Kamatani N, Hori M, Isobe M, Nakamura Y, Tanaka T. A functional SNP in ITIH3 is associated with susceptibility to myocardial infarction. J Hum Genet. 2007; 52 (3): 220-229. ( PubMed, DOI )

Ozaki K, Sato H, Iida A, Mizuno H, Nakamura T, Miyamoto Y, Takahashi A, Tsunoda T, Ikegawa S, Kamatani N, Hori M, Nakamura Y, Tanaka T. A functional SNP in PSMA6 confers risk of myocardial infarction in the Japanese population. Nat Genet. 2006.08; 38 (8): 921-925. ( PubMed, DOI )

Mizuno H, Sato H, Sakata Y, Ohnishi Y, Hishida E, Kinjo K, Nakatani D, Shimizu M, Kondo H, Tanaka T, Ozaki K, Hirayama A, Ito H, Otsu K, Hori M. Impact of atherosclerosis-related gene polymorphisms on mortality and recurrent events after myocardial infarction. Atherosclerosis. 2006.04; 185 (2): 400-405. ( PubMed, DOI )

Tanaka T, Ozaki K. Inflammation as a risk factor for myocardial infarction. J Hum Genet. 2006; 51 (7): 595-604. ( PubMed, DOI )

Ozaki K, Tanaka T. Genome-wide association study to identify single-nucleotide polymorphisms conferring risk of myocardial infarction. Methods Mol Med. 2006; 128 173-180. ( PubMed, DOI )

Ishii N, Ozaki K, Sato H, Mizuno H, Saito S, Takahashi A, Miyamoto Y, Ikegawa S, Kamatani N, Hori M, Saito S, Nakamura Y, Tanaka T. Identification of a novel non-coding RNA, MIAT, that confers risk of myocardial infarction. J Hum Genet. 2006; 51 (12): 1087-1099. ( PubMed, DOI )

Kato M, Sekine A, Ohnishi Y, Johnson TA, Tanaka T, Nakamura Y, Tsunoda T. Linkage disequilibrium of evolutionarily conserved regions in the human genome. BMC Genomics. 2006; 7 326. ( PubMed, DOI )

A haplotype map of the human genome. Nature. 2005.10; 437 (7063): 1299-1320. ( PubMed, DOI )

Ozaki K, Tanaka T. Genome-wide association study to identify SNPs conferring risk of myocardial infarction and their functional analyses. Cell Mol Life Sci. 2005.08; 62 (16): 1804-1813. ( PubMed, DOI )

Ohtsubo S, Iida A, Nitta K, Tanaka T, Yamada R, Ohnishi Y, Maeda S, Tsunoda T, Takei T, Obara W, Akiyama F, Ito K, Honda K, Uchida K, Tsuchiya K, Yumura W, Ujiie T, Nagane Y, Miyano S, Suzuki Y, Narita I, Gejyo F, Fujioka T, Nihei H, Nakamura Y. Association of a single-nucleotide polymorphism in the immunoglobulin mu-binding protein 2 gene with immunoglobulin A nephropathy. J Hum Genet. 2005; 50 (1): 30-35. ( PubMed, DOI )

Iida A, Ozaki K, Tanaka T, Nakamura Y. Fine-scale SNP map of an 11-kb genomic region at 22q13.1 containing the galectin-1 gene. J Hum Genet. 2005; 50 (1): 42-45. ( PubMed, DOI )

Onda M, Emi M, Yoshida A, Miyamoto S, Akaishi J, Asaka S, Mizutani K, Shimizu K, Nagahama M, Ito K, Tanaka T, Tsunoda T. Comprehensive gene expression profiling of anaplastic thyroid cancers with cDNA microarray of 25 344 genes. Endocr Relat Cancer. 2004.12; 11 (4): 843-854. ( PubMed, DOI )

Onda M, Emi M, Nagai H, Nagahata T, Tsumagari K, Fujimoto T, Akiyama F, Sakamoto G, Makita M, Kasumi F, Miki Y, Tanaka T, Tsunoda T, Nakamura Y. Gene expression patterns as marker for 5-year postoperative prognosis of primary breast cancers. J Cancer Res Clin Oncol. 2004.09; 130 (9): 537-545. ( PubMed, DOI )

Tsunoda T, Lathrop GM, Sekine A, Yamada R, Takahashi A, Ohnishi Y, Tanaka T, Nakamura Y. Variation of gene-based SNPs and linkage disequilibrium patterns in the human genome. Hum Mol Genet. 2004.08; 13 (15): 1623-1632. ( PubMed, DOI )

Integrating ethics and science in the International HapMap Project. Nat Rev Genet. 2004.06; 5 (6): 467-475. ( PubMed, DOI )

Ozaki K, Inoue K, Sato H, Iida A, Ohnishi Y, Sekine A, Sato H, Odashiro K, Nobuyoshi M, Hori M, Nakamura Y, Tanaka T. Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-alpha secretion in vitro. Nature. 2004.05; 429 (6987): 72-75. ( PubMed, DOI )

Nagahata T, Onda M, Emi M, Nagai H, Tsumagari K, Fujimoto T, Hirano A, Sato T, Nishikawa K, Akiyama F, Sakamoto G, Kasumi F, Miki Y, Tanaka T, Tsunoda T. Expression profiling to predict postoperative prognosis for estrogen receptor-negative breast cancers by analysis of 25,344 genes on a cDNA microarray. Cancer Sci. 2004.03; 95 (3): 218-225. ( PubMed )

Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S. Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat Genet. 2004.01; 36 (1): 40-45. ( PubMed, DOI )

The International HapMap Project. Nature. 2003.12; 426 (6968): 789-796. ( PubMed, DOI )

Sasaki Y, Mita H, Toyota M, Ishida S, Morimoto I, Yamashita T, Tanaka T, Imai K, Nakamura Y, Tokino T. Identification of the interleukin 4 receptor alpha gene as a direct target for p73. Cancer Res. 2003.12; 63 (23): 8145-8152. ( PubMed )

Watanabe G, Nishimori H, Irifune H, Sasaki Y, Ishida S, Zembutsu H, Tanaka T, Kawaguchi S, Wada T, Hata J, Kusakabe M, Yoshida K, Nakamura Y, Tokino T. Induction of tenascin-C by tumor-specific EWS-ETS fusion genes. Genes Chromosomes Cancer. 2003.03; 36 (3): 224-232. ( PubMed, DOI )

Tsukada S, Iwai M, Nishiu J, Itoh M, Tomoike H, Horiuchi M, Nakamura Y, Tanaka T. Inhibition of experimental intimal thickening in mice lacking a novel G-protein-coupled receptor. Circulation. 2003.01; 107 (2): 313-319. ( PubMed )

Iida A, Tanaka T, Nakamura Y. High-density SNP map of human ITR, a gene associated with vascular remodeling. J Hum Genet. 2003; 48 (4): 170-172. ( PubMed, DOI )

Obara W, Iida A, Suzuki Y, Tanaka T, Akiyama F, Maeda S, Ohnishi Y, Yamada R, Tsunoda T, Takei T, Ito K, Honda K, Uchida K, Tsuchiya K, Yumura W, Ujiie T, Nagane Y, Nitta K, Miyano S, Narita I, Gejyo F, Nihei H, Fujioka T, Nakamura Y. Association of single-nucleotide polymorphisms in the polymeric immunoglobulin receptor gene with immunoglobulin A nephropathy (IgAN) in Japanese patients. J Hum Genet. 2003; 48 (6): 293-299. ( PubMed, DOI )

Iida A, Ozaki K, Ohnishi Y, Tanaka T, Nakamura Y. Identification of 46 novel SNPs in the 130-kb region containing a myocardial infarction susceptibility gene on chromosomal band 6p21. J Hum Genet. 2003; 48 (9): 476-479. ( PubMed, DOI )

Ozaki K, Ohnishi Y, Iida A, Sekine A, Yamada R, Tsunoda T, Sato H, Sato H, Hori M, Nakamura Y, Tanaka T. Functional SNPs in the lymphotoxin-alpha gene that are associated with susceptibility to myocardial infarction. Nat Genet. 2002.12; 32 (4): 650-654. ( PubMed, DOI )

Nishimori H, Sasaki Y, Yoshida K, Irifune H, Zembutsu H, Tanaka T, Aoyama T, Hosaka T, Kawaguchi S, Wada T, Hata J, Toguchida J, Nakamura Y, Tokino T. The Id2 gene is a novel target of transcriptional activation by EWS-ETS fusion proteins in Ewing family tumors. Oncogene. 2002.11; 21 (54): 8302-8309. ( PubMed, DOI )

Ishiguro H, Shimokawa T, Tsunoda T, Tanaka T, Fujii Y, Nakamura Y, Furukawa Y. Isolation of HELAD1, a novel human helicase gene up-regulated in colorectal carcinomas. Oncogene. 2002.09; 21 (41): 6387-6394. ( PubMed, DOI )

Inoue K, Matsuda K, Itoh M, Kawaguchi H, Tomoike H, Aoyagi T, Nagai R, Hori M, Nakamura Y, Tanaka T. Osteopenia and male-specific sudden cardiac death in mice lacking a zinc transporter gene, Znt5. Hum Mol Genet. 2002.07; 11 (15): 1775-1784. ( PubMed )

Takei T, Iida A, Nitta K, Tanaka T, Ohnishi Y, Yamada R, Maeda S, Tsunoda T, Takeoka S, Ito K, Honda K, Uchida K, Tsuchiya K, Suzuki Y, Fujioka T, Ujiie T, Nagane Y, Miyano S, Narita I, Gejyo F, Nihei H, Nakamura Y. Association between single-nucleotide polymorphisms in selectin genes and immunoglobulin A nephropathy. Am J Hum Genet. 2002.03; 70 (3): 781-786. ( PubMed, DOI )

Sasaki Y, Ishida S, Morimoto I, Yamashita T, Kojima T, Kihara C, Tanaka T, Imai K, Nakamura Y, Tokino T. The p53 family member genes are involved in the Notch signal pathway. J Biol Chem. 2002.01; 277 (1): 719-724. ( PubMed, DOI )

Hirakawa M, Tanaka T, Hashimoto Y, Kuroda M, Takagi T, Nakamura Y. JSNP: a database of common gene variations in the Japanese population. Nucleic Acids Res. 2002.01; 30 (1): 158-162. ( PubMed )

Akiyama F, Tanaka T, Yamada R, Ohnishi Y, Tsunoda T, Maeda S, Takei T, Obara W, Ito K, Honda K, Uchida K, Tsuchiya K, Nitta K, Yumura W, Nihei H, Ujiie T, Nagane Y, Miyano S, Suzuki Y, Fujioka T, Narita I, Gejyo F, Nakamura Y. Single-nucleotide polymorphisms in the class II region of the major histocompatibility complex in Japanese patients with immunoglobulin A nephropathy. J Hum Genet. 2002; 47 (10): 532-538. ( PubMed, DOI )

Iwasa H, Kurabayashi M, Nagai R, Nakamura Y, Tanaka T. Twenty single-nucleotide polymorphisms in four genes encoding cardiac ion channels. J Hum Genet. 2002; 47 (4): 208-212. ( PubMed, DOI )

Haga H, Yamada R, Ohnishi Y, Nakamura Y, Tanaka T. Gene-based SNP discovery as part of the Japanese Millennium Genome Project: identification of 190,562 genetic variations in the human genome. Single-nucleotide polymorphism. J Hum Genet. 2002; 47 (11): 605-610. ( PubMed, DOI )

Fujita M, Furukawa Y, Tsunoda T, Tanaka T, Ogawa M, Nakamura Y. Up-regulation of the ectodermal-neural cortex 1 (ENC1) gene, a downstream target of the beta-catenin/T-cell factor complex, in colorectal carcinomas. Cancer Res. 2001.11; 61 (21): 7722-7726. ( PubMed )

Kihara C, Tsunoda T, Tanaka T, Yamana H, Furukawa Y, Ono K, Kitahara O, Zembutsu H, Yanagawa R, Hirata K, Takagi T, Nakamura Y. Prediction of sensitivity of esophageal tumors to adjuvant chemotherapy by cDNA microarray analysis of gene-expression profiles. Cancer Res. 2001.09; 61 (17): 6474-6479. ( PubMed )

Lin YM, Ono K, Satoh S, Ishiguro H, Fujita M, Miwa N, Tanaka T, Tsunoda T, Yang KC, Nakamura Y, Furukawa Y. Identification of AF17 as a downstream gene of the beta-catenin/T-cell factor pathway and its involvement in colorectal carcinogenesis. Cancer Res. 2001.09; 61 (17): 6345-6349. ( PubMed )

Ishiguro H, Tsunoda T, Tanaka T, Fujii Y, Nakamura Y, Furukawa Y. Identification of AXUD1, a novel human gene induced by AXIN1 and its reduced expression in human carcinomas of the lung, liver, colon and kidney. Oncogene. 2001.08; 20 (36): 5062-5066. ( PubMed, DOI )

Matsushima-Nishiu M, Unoki M, Ono K, Tsunoda T, Minaguchi T, Kuramoto H, Nishida M, Satoh T, Tanaka T, Nakamura Y. Growth and gene expression profile analyses of endometrial cancer cells expressing exogenous PTEN. Cancer Res. 2001.05; 61 (9): 3741-3749. ( PubMed )

Kitahara O, Furukawa Y, Tanaka T, Kihara C, Ono K, Yanagawa R, Nita ME, Takagi T, Nakamura Y, Tsunoda T. Alterations of gene expression during colorectal carcinogenesis revealed by cDNA microarrays after laser-capture microdissection of tumor tissues and normal epithelia. Cancer Res. 2001.05; 61 (9): 3544-3549. ( PubMed )

Suzuki Y, Taira H, Tsunoda T, Mizushima-Sugano J, Sese J, Hata H, Ota T, Isogai T, Tanaka T, Morishita S, Okubo K, Sakaki Y, Nakamura Y, Suyama A, Sugano S. Diverse transcriptional initiation revealed by fine, large-scale mapping of mRNA start sites. EMBO Rep. 2001.05; 2 (5): 388-393. ( PubMed, DOI )

Suzuki Y, Tsunoda T, Sese J, Taira H, Mizushima-Sugano J, Hata H, Ota T, Isogai T, Tanaka T, Nakamura Y, Suyama A, Sakaki Y, Morishita S, Okubo K, Sugano S. Identification and characterization of the potential promoter regions of 1031 kinds of human genes. Genome Res. 2001.05; 11 (5): 677-684. ( PubMed, DOI )

Yamada R, Tanaka T, Unoki M, Nagai T, Sawada T, Ohnishi Y, Tsunoda T, Yukioka M, Maeda A, Suzuki K, Tateishi H, Ochi T, Nakamura Y, Yamamoto K. Association between a single-nucleotide polymorphism in the promoter of the human interleukin-3 gene and rheumatoid arthritis in Japanese patients, and maximum-likelihood estimation of combinatorial effect that two genetic loci have on susceptibility to the disease. Am J Hum Genet. 2001.03; 68 (3): 674-685. ( PubMed, DOI )

Kunishima S, Kojima T, Matsushita T, Tanaka T, Tsurusawa M, Furukawa Y, Nakamura Y, Okamura T, Amemiya N, Nakayama T, Kamiya T, Saito H. Mutations in the NMMHC-A gene cause autosomal dominant macrothrombocytopenia with leukocyte inclusions (May-Hegglin anomaly/Sebastian syndrome). Blood. 2001.02; 97 (4): 1147-1149. ( PubMed )

Kato T, Satoh S, Okabe H, Kitahara O, Ono K, Kihara C, Tanaka T, Tsunoda T, Yamaoka Y, Nakamura Y, Furukawa Y. Isolation of a novel human gene, MARKL1, homologous to MARK3 and its involvement in hepatocellular carcinogenesis. Neoplasia. 2001.01; 3 (1): 4-9. ( PubMed, DOI )

Iwasa H, Kurabayashi M, Nagai R, Nakamura Y, Tanaka T. Multiple single-nucleotide polymorphisms (SNPs) in the Japanese population in six candidate genes for long QT syndrome. J Hum Genet. 2001; 46 (3): 158-162. ( PubMed, DOI )

Itoh T, Kikuchi K, Odagawa Y, Takata S, Yano K, Okada S, Haneda N, Ogawa S, Nakano O, Kawahara Y, Kasai H, Nakayama T, Fukutomi T, Sakurada H, Shimizu A, Yazaki Y, Nagai R, Nakamura Y, Tanaka T. Correlation of genetic etiology with response to beta-adrenergic blockade among symptomatic patients with familial long-QT syndrome. J Hum Genet. 2001; 46 (1): 38-40. ( PubMed, DOI )

Iida A, Ohnishi Y, Ozaki K, Ariji Y, Nakamura Y, Tanaka T. High-density single-nucleotide polymorphism (SNP) map in the 96-kb region containing the entire human DiGeorge syndrome critical region 2 (DGCR2) gene at 22q11.2. J Hum Genet. 2001; 46 (10): 604-608. ( PubMed, DOI )

Iwasa H, Kurabayashi M, Nagai R, Nakamura Y, Tanaka T. Genetic variations in five genes involved in the excitement of cardiomyocytes. J Hum Genet. 2001; 46 (9): 549-552. ( PubMed, DOI )

Ohnishi Y, Tanaka T, Ozaki K, Yamada R, Suzuki H, Nakamura Y. A high-throughput SNP typing system for genome-wide association studies. J Hum Genet. 2001; 46 (8): 471-477. ( PubMed, DOI )

Nakajima T, Kurabayashi M, Ohyama Y, Kaneko Y, Furukawa T, Itoh T, Taniguchi Y, Tanaka T, Nakamura Y, Hiraoka M, Nagai R. Characterization of S818L mutation in HERG C-terminus in LQT2. Modification of activation-deactivation gating properties. FEBS Lett. 2000.09; 481 (2): 197-203. ( PubMed )

Ono K, Tanaka T, Tsunoda T, Kitahara O, Kihara C, Okamoto A, Ochiai K, Takagi T, Nakamura Y. Identification by cDNA microarray of genes involved in ovarian carcinogenesis. Cancer Res. 2000.09; 60 (18): 5007-5011. ( PubMed )

Yamauchi T, Tada M, Houkin K, Tanaka T, Nakamura Y, Kuroda S, Abe H, Inoue T, Ikezaki K, Matsushima T, Fukui M. Linkage of familial moyamoya disease (spontaneous occlusion of the circle of Willis) to chromosome 17q25. Stroke. 2000.04; 31 (4): 930-935. ( PubMed )

Ohnishi Y, Tanaka T, Yamada R, Suematsu K, Minami M, Fujii K, Hoki N, Kodama K, Nagata S, Hayashi T, Kinoshita N, Sato H, Sato H, Kuzuya T, Takeda H, Hori M, Nakamura Y. Identification of 187 single nucleotide polymorphisms (SNPs) among 41 candidate genes for ischemic heart disease in the Japanese population. Hum Genet. 2000.03; 106 (3): 288-292. ( PubMed )

Yamada R, Tanaka T, Ohnishi Y, Suematsu K, Minami M, Seki T, Yukioka M, Maeda A, Murata N, Saiki O, Teshima R, Kudo O, Ishikawa K, Ueyosi A, Tateishi H, Inaba M, Goto H, Nishizawa Y, Tohma S, Ochi T, Yamamoto K, Nakamura Y. Identification of 142 single nucleotide polymorphisms in 41 candidate genes for rheumatoid arthritis in the Japanese population. Hum Genet. 2000.03; 106 (3): 293-297. ( PubMed )

Iwasa H, Itoh T, Nagai R, Nakamura Y, Tanaka T. Twenty single nucleotide polymorphisms (SNPs) and their allelic frequencies in four genes that are responsible for familial long QT syndrome in the Japanese population. J Hum Genet. 2000; 45 (3): 182-183. ( PubMed, DOI )

Seki T, Tanaka T, Nakamura Y. Genomic structure and multiple single-nucleotide polymorphisms (SNPs) of the thiopurine S-methyltransferase (TPMT) gene. J Hum Genet. 2000; 45 (5): 299-302. ( PubMed, DOI )

Tsunoda T, Yamada R, Tanaka T, Ohnishi Y, Kamatani N. Environmental factor dependent maximum likelihood method for association study targeted to personalized medicine. Genome Inform Ser Workshop Genome Inform. 2000; 11 96-105. ( PubMed )

Kunishima S, Kojima T, Tanaka T, Kamiya T, Ozawa K, Nakamura Y, Saito H. Mapping of a gene for May-Hegglin anomaly to chromosome 22q. Hum Genet. 1999.11; 105 (5): 379-383. ( PubMed )

Nakajima T, Furukawa T, Hirano Y, Tanaka T, Sakurada H, Takahashi T, Nagai R, Itoh T, Katayama Y, Nakamura Y, Hiraoka M. Voltage-shift of the current activation in HERG S4 mutation (R534C) in LQT2. Cardiovasc Res. 1999.11; 44 (2): 283-293. ( PubMed )

Mikami M, Yasuda T, Terao A, Nakamura M, Ueno S, Tanabe H, Tanaka T, Onuma T, Goto Y, Kaneko S, Sano A. Localization of a gene for benign adult familial myoclonic epilepsy to chromosome 8q23.3-q24.1. Am J Hum Genet. 1999.09; 65 (3): 745-751. ( PubMed )

Tsujikawa M, Kurahashi H, Tanaka T, Nishida K, Shimomura Y, Tano Y, Nakamura Y. Identification of the gene responsible for gelatinous drop-like corneal dystrophy. Nat Genet. 1999.04; 21 (4): 420-423. ( PubMed, DOI )

Tsujikawa M, Kurahashi H, Tanaka T, Okada M, Yamamoto S, Maeda N, Watanabe H, Inoue Y, Kiridoshi A, Matsumoto K, Ohashi Y, Kinoshita S, Shimomura Y, Nakamura Y, Tano Y. Homozygosity mapping of a gene responsible for gelatinous drop-like corneal dystrophy to chromosome 1p. Am J Hum Genet. 1998.10; 63 (4): 1073-1077. ( PubMed, DOI )

Nishiu J, Tanaka T, Nakamura Y. Identification of a novel gene (ECM2) encoding a putative extracellular matrix protein expressed predominantly in adipose and female-specific tissues and its chromosomal localization to 9q22.3. Genomics. 1998.09; 52 (3): 378-381. ( PubMed, DOI )

Itoh T, Tanaka T, Nagai R, Kikuchi K, Ogawa S, Okada S, Yamagata S, Yano K, Yazaki Y, Nakamura Y. Genomic organization and mutational analysis of KVLQT1, a gene responsible for familial long QT syndrome. Hum Genet. 1998.09; 103 (3): 290-294. ( PubMed )

Nakajima T, Furukawa T, Tanaka T, Katayama Y, Nagai R, Nakamura Y, Hiraoka M. Novel mechanism of HERG current suppression in LQT2: shift in voltage dependence of HERG inactivation. Circ Res. 1998.08; 83 (4): 415-422. ( PubMed )

Itoh T, Tanaka T, Nagai R, Kamiya T, Sawayama T, Nakayama T, Tomoike H, Sakurada H, Yazaki Y, Nakamura Y. Genomic organization and mutational analysis of HERG, a gene responsible for familial long QT syndrome. Hum Genet. 1998.04; 102 (4): 435-439. ( PubMed )

Nishiu J, Tanaka T, Nakamura Y. Isolation and chromosomal mapping of the human homolog of perilipin (PLIN), a rat adipose tissue-specific gene, by differential display method. Genomics. 1998.03; 48 (2): 254-257. ( PubMed, DOI )

Nakagawa H, Koyama K, Tanaka T, Miyoshi Y, Ando H, Baba S, Watatani M, Yasutomi M, Monden M, Nakamura Y. Localization of the gene responsible for Peutz-Jeghers syndrome within a 6-cM region of chromosome 19p13.3. Hum Genet. 1998.02; 102 (2): 203-206. ( PubMed )

Yamane-Tanaka Y, Kogawa K, Tanaka T, Nakamura Y, Isomura M. Heterozygosities and allelic frequencies of 358 dinucleotide-repeat marker loci in the Japanese population. J Hum Genet. 1998; 43 (3): 165-168. ( PubMed, DOI )

Itoh M, Tsukada S, Orita T, Nishiu J, Tomoike H, Nakamura Y, Tanaka T. Identification by differential display of eight known genes induced during in vivo intimal hyperplasia. J Hum Genet. 1998; 43 (1): 9-13. ( PubMed, DOI )

Tanaka T, Nagai R, Tomoike H, Takata S, Yano K, Yabuta K, Haneda N, Nakano O, Shibata A, Sawayama T, Kasai H, Yazaki Y, Nakamura Y. Four novel KVLQT1 and four novel HERG mutations in familial long-QT syndrome. Circulation. 1997.02; 95 (3): 565-567. ( PubMed )

Tanaka T, Ogiwara A, Uchiyama I, Takagi T, Yazaki Y, Nakamura Y. Construction of a normalized directionally cloned cDNA library from adult heart and analysis of 3040 clones by partial sequencing. Genomics. 1996.07; 35 (1): 231-235. ( PubMed, DOI )

Tanaka T, Inazawa J, Nakamura Y. Molecular cloning and mapping of a human cDNA for cytosolic malate dehydrogenase (MDH1). Genomics. 1996.02; 32 (1): 128-130. ( PubMed, DOI )

Tanaka T, Inazawa J, Nakamura Y. Molecular cloning of a human cDNA encoding putative cysteine protease (PRSC1) and its chromosome assignment to 14q32.1. Cytogenet Cell Genet. 1996; 74 (1-2): 120-123. ( PubMed )

Chatterjee A, Tanaka T, Parrish JE, Herman GE. Refined mapping of caltractin in human Xq28 and in the homologous region of the mouse X chromosome places the gene within the bare patches (Bpa) and striated (Str) critical regions. Mamm Genome. 1995.11; 6 (11): 802-804. ( PubMed )

Tanaka T, Okui K, Nakamura Y. Assignment of the human caltractin gene (CALT) to Xq28 by fluorescence in situ hybridization. Genomics. 1994.12; 24 (3): 609-610. ( PubMed )

Tanaka T, Nakahara K, Kato N, Imai T, Yamazaki T, Tomita H, Shimokawa H, Matsuhashi H, Sato N, Matsui M. Genetic linkage analyses of Romano-Ward syndrome (RWS) in 13 Japanese families. Hum Genet. 1994.10; 94 (4): 380-384. ( PubMed )

Kanai M, Tanaka T, Okada Y. Empirical estimation of genome-wide significance thresholds based on the 1000 Genomes Project dataset. ICHG2016 2016.04.07

Fares Taie L, Gerber S, Tawara A, Ramirez-Miranda A, Douet JY, Verdin H, Zanteno JC, Kondo H, Passet B, Yamamoto K, Iwai M, Tanaka T, Nakamura Y, Kimura W, Munnich A, Baere ED, Raymond-Letron I, Kaplan J, Calvas P, Roche O, Rozet JM. Submicroscopic deletions at 13q32.1 cause congenital microcoria. ICHG2016 2016.04.05

Onouchi Y, Nakagawa H, Shigemizu D, Ozaki K, Nakamura Y, Asami Y, Seki M, Kobayashi T, Kochi Y, Toda T, Satake W, Hata A, Tsunoda T, Tanaka T, Japan Kawasaki Disease Genome Consortium. Search for genetic variations responsible for giant coronary aneurysms in Kawasaki disease patients by whole exome sequencing. ICHG2016 2016.04.04

Takeaki Sudo, Yukinori Okada, Hiroaki Kobayashi, Misa Gokyu, Yuichi Izumi, Toshihiro Tanaka. Whole-exome sequencing reveals a novel gene as a cause of Aggressive periodontitis in Japanese consanguineous families. The 13th International Congress of Human Genetics 2016.04.04

El Rouby N, McDonough CW, Gong Y, McClure LA, Mitchell BD, Horenstein RB, Talbert RL, Takahashi A, Tanaka T, Kubo M, Pepine CJ, Cooper-DeHoff RM, Benavente OR, Shuldiner AR, Johnson JA. Novel genetic loci for resistant hypertension discovered through a genome-wide association approach (GWAS) in the INternational VErapamil SR-Trandolapril STudy (INVEST) and the Secondary Prevention of Subcortical Strokes (SPS3) Study. American Society of Human Genetics 2015.10

Higuchi C, Tanaka T and Okada Y. Systematic comparison of machine learning methods for identification of miRNA species as disease biomarkers. The IWBBIO 2015 (3rd International Work-Conference on Bioinformatics and Biomedical Engineering) 2015.04 Spain Granada

Aiba T, Makimoto H, Makiyama T, Watanabe H, Hayashi K, Nakano Y, Miyauchi Y, Morita H, Aonuma K, Hagiwara N, Fukuda K, Yoshinaga M, Horigome H, Sumitomo N, Tanaka T, Sekine A, Shiraishi I, Kusano K, Miyamoto Y, Kamakura S, Yasuda S, Ogawa H, Makita N, Horie M, Shimizu W. Diverse gender difference of arrhythmic risk in patients with congenital Long QT Syndrome: from Japanese congenital LQTS multicenter registry. AHA 2014 2014.11 Chicago

Ozaki K, Sakata Y, Suna S, Onouchi Y, Tsunoda T, Kubo M, Komuro I, Tanaka T. A replication study for fifteen coronary artery disease susceptible loci in a Japanese population. ASHG 2014 2014.10 San Diego

Rouby N, McDonough C, Gong Y, Pepine C, Takahashi A, Tanaka T, Kubo M, Cooper-DeHoff R, Johnson J. Genome-wide association study of resistant hypertension in INVEST. ASHG 2014 2014.10 San Diego

Johnson T, Boroevich K, Tanaka T, Qi L, He, Xu M, Wu T, Kubo M, Tsunoda T. Integrated analysis of known height association signals with novel signals from an East Asian GWAS decodes the genetic architecture of height through in silico functional candidate prioritization and gene network analysis. ASHG 2014 2014.10 San Diego

Ozaki K, Morizono T, Onouchi Y, Takahashi A, Tsunoda T, Kubo M, Nakamura Y, Tanaka T. . Genome-wide association study for arteriosclerosis obliterans in a Japanese population. American Society of Human Genetics . ASHG 2013 2013.10

Onouchi Y, Fukazawa R, Ozaki K, Terai M, Hamada H, Honda T, Suzuki H, Suenaga T, Takeuchi T, Yasukawa K, Ebata R, Higashi K, Saji T, Kemmotsu Y, Takatsuki S, Ouchi K, Kishi F, Yoshikawa T, Nagai T, Hamamoto K, Sato Y, Abe J, Seki M, Kobayashi T, Takahashi A, Tsunoda T, Kubo M, Nakamura Y, Hata A, Tanaka T.. Variations in ORAI1 gene associated with Kawasaki disease. . ASHG 2013 2013.10

Ozaki K, and Tanaka T. Whole genome association study for atrial fibrillation in a Japanese population. ISHR 2013 2013.07

Ozaki K, Morizono T, Tsunoda T, Kubo M, Nakamura Y, Tanaka T. . Genetic risk factors for atrial fibrillation in the Japanese population.. ESHG2013 2013.06

Onouchi Y, Ozaki K, Terai M, Hamada H, Suzuki H, Suenaga T, Suzuki Y, Yasukawa K, Ebata R, Saji T, Kemmotsu Y, Ouchi K, Kishi F, Yoshikawa T, Nagai T, Hamamoto K, Sato Y, Sasago K, Takahashi A, Kubo M, Tsunoda T, Hata A, Nakamura Y, Tanaka T. . A fine mapping of the genetic variation influencing the ratio of alternatively spliced CD40 transcripts and conferring susceptibility to Kawasaki disease. . ASHG 2012 2012.11

Ozaki K, Kubo M, Tsunoda T, Onouchi Y, Kamatani N, Nakamura Y, Tanaka T. . Six chromosome loci for atrial fibrillation susceptibility identified in Japanese.. AHA 2012 2012.11

Ozaki K, Onouchi Y, Kamatani N, Tsunoda T, Kubo M, Nakamura Y, Tanaka T. . Genome-wide association study for atrial fibrillation in the Japanese population. . ASHG 2012 2012.11

Ozaki K, Tanaka T. . Identification of protein that interact BRAP, encoded by a gene associated with myocardial infarction susceptibility.. World Congress of Cardiology Scientific Sessions 2012.04

Onouchi Y, Ozaki K, Suzuki H, Terai M, Hata A, Tanaka T. . ITPKC and CASP3 polymorphisms and risks for IVIG unresponsiveness and coronary artery lesion formation in Kawasaki disease. . Human Genome Meeting 2012.03

Ozaki K, Onouchi Y, Nakamura Y, Tanaka T. . BRAP, encoded by a gene associated with myocardial infarction, binds several key inflammatory molecules.. ICHG 2011 2011.10

Onouchi Y, Ozaki K, Burns J.C, Shimizu C, Terai M, Hamada H, Suzuki H, Suenaga T, Suzuki Y, Yasukawa K, Ebata R, Saji T, Kemmotsu Y, Ouchi K, Kishi F,Yoshikawa T, Nagai T, Hamamoto K, Sato Y, Sasago K, Takahashi A, Kamatani N, Kubo M, Tsunoda T, Hata A, Nakamura Y, Tanaka T.. Genome-wide association study identified new susceptibility loci for Kawasaki disease. . ICHG 2011 2011.10

Tanaka T.. Genetic Epidemiology~Understanding the human diversity towards personalized medicine~. . The 6th International Syompsium of Nagasaki University Global COE program 2011.10

Tanaka T.. BioBank Japan. . KOGO satellite session 2011.09

Todd J, 田中敏博, 久保充明, 中村祐輔, 角田達彦 . Analyzing contiguous homozygosity to quantify haplotype structure differences between case and control samples. 日本人類遺伝学会第55回大会 2010.10

Yamagata K, Horie M, Ogawa S, Aizawa Y, Kusano K, Ohe T, Yamagishi M, Makita N, Tanaka T, Makiyama T, Akao M, Hagiwara N, Kishi R, Miyamoto Y, Kamakura S, Shimizu W. . Clinical Phenotype and Prognosis of Probands with Brugada Syndrome in Relation to SCN5A Mutation. . 第74回日本循環器学会総会・学術集会 2010.03

Makimoto H, Yamagata K, Horie M, Ogawa S, Aizawa Y, Kusano K, Ohe T, Yamagishi M, Makita N, Tanaka T, Makiyama T, Akao M, Yoshinaga M, Miyamoto Y, Kamakura S, Shimizu W. . Clinical Features of Long QT Syndrome in Pre-Elementary Age.. 第74回日本循環器学会総会・学術集会 2010.03

Ozaki K, Sato H, Inoue K, Tsunoda T, Sakata Y, Mizuno H, Onouchi Y, Odashiro K, Nobuyoshi M, Juo H S-H, Hori H, Nakamura Y, Tanaka T. . SNPs in Genes Encoding an Inflammatory Cascade Confer Risk of Myocardial Infarction.. 第74回日本循環器学会総会・学術集会 2010.03

Yamagata K, Horie M, Ogawa S, Aizawa Y, Kusano K, Ohe T, Yamagishi M, Makita N, Tanaka T, Akao M, Yoshinaga M, Okamura H, Noda T, Miyamoto Y, Kamakura S, Shimizu W.. Clinical Phenotype of Japanese LQT3 Form of Congenital Long QT Syndrome by Location of Mutation from Japanese Multicenter Registry. . 第73回日本循環器学会総会・学術集会 2009.03

Ozaki K, Sato H, Inoue K, Tsunoda T, Sakata Y, Mizuno H, Aoki A, Odashiro K, Nobuyoshi M, Juo H S-H, Hori M, Nakamura Y, Tanaka T. . A Functional Variation in a Gene Encoding One of Galectin-2 Binding Proteins Confers Risk of Myocardial Infarction in Asian Populations.. 第73回日本循環器学会総会・学術集会 2009.03

Ozaki K, Sato H, Inoue K, Mizuno H, Sakata Y, Odashiro K, Nobuyoshi M, Hori M, Nakamura Y, Tanaka T. . Large Scale SNPs Association Study to Identify Genes Confer Risk of Myocardial Infarction. . 第73回日本循環器学会総会・学術集会 2009.03

Aoki A, Ozaki K, Sato H, Takahashi A, Kubo M, Sakata Y, Mizuno H, Kamatani N, Tsunoda T, Takano H, Yasutake M, Mizuno K, Hori M, Nakamura Y, Tanaka T.. Identification of a Locus on Chromosome 5p that Confers Risk of Coronary Artery Disease by Genome Wide Association Study. . 第73回日本循環器学会総会・学術集会 2009.03

Yamagata K, Horie M, Ogawa S, Aizawa Y, Kusano K, Ohe T, Yamagishi M, Makita N, Tanaka T, Akao M, Kishi R, Okamura H, Noda T, Satomi K, Suyama K, Kurita T, Aihara N, Kamaukura S, Miyamoto Y, Shimizu W. . Clinical and Electrocardiographic Characteristics of Japanese Probands with Brugada Syndrome with an SCN5A Mutation from Japanese Multicenter Registry. . 第73回日本循環器学会総会・学術集会 2009.03

Kato M, Miya F, Kanemura Y, Tanaka T, Nakamura Y, Tsunoda T. . Patterns of high-resolution recombination rates in human genes.. HGM 2008 2008.09

Tanaka T.. Genetic background of myocardial infarction.. Mendel Symposium II Genes and the Heart 2008.09

Ozaki K, Sato H, Ishii N, Ebana Y, Iida A, Mizuno H, Hori M, Nakamura Y, and Tanaka T. . Large scale SNPs association study to identify genes confer risk of myocardial infarction. . 14th World Congress on Heart Disease 2008.07

Tanaka T.. Genetic backgrounds of myocardial infarction. . The 2008 EAUHGS Symposium and the 8th EAUHGS Annual Meeting 2008.07

Yamagata K, Horie M, Ogawa S, Aizawa Y, Ohe T, Yamagishi M, Makita N, Tanaka T, Akao M, Yoshinaga M, Okamura H, Noda T, Miyamoto Y, Kamakura S, Shimizu W. . Clinical Phenotype of Japanese LQT1 form of congenital long QT syndrome by location and coding type from Japanese multicenter registry. . 第72回日本循環器学会総会・学術集会 2008.03

Tanaka T.. Single-Nucleotide Polymorphisms Confer Risk of Myocardial infarction. . AHA 2007 2007.11

Ozaki K, Sato H, Iida A, Mizuno H, Takahashi A, Nakamura T, Lwin H, Ikegawa S, Hri M, Nakamura Y, Tanaka T. . 52,608 gene-based SNPs association study to identify genes related to myocardial infarction. . ASHG 2007 2007.10

Tanaka T.. Biobank Japan.. International Society for Biological and Environmental Repositories 2007.05

Ozaki K, Sato H, Iida A, Mizuno H, Hori M, Nakamura Y, and Tanaka T. . A functional SNP in the proteasome subunit alpha type 6 gene confers risk of myocardial infarction in Japanese population. . 第71回日本循環器学会総会・学術集会 2007.03

Ozaki K, Ishii N, Sato H, Mizuno H, Hori M, Saito S, Nakamura Y, and Tanaka T.. Identification of a novel non-coding RNA, MIAT, that confers risk of myocardial Infarction. . 第71回日本循環器学会総会・学術集会 2007.03

Tanaka T.. Identification of genes associated with common diseases by large-scale genetic association study-Studies on myocardial infarction. . The 2nd annual international symposium of genomic medicine and pharmacogenomics 2007.03

Tanaka T.. Identification of genes associated with common diseases by large-scale genetic association study-Studies on myocardial infarction. . Medical Science Seminar Series 2007.03

Ozaki K, Sato H, Iida A, Mizuno H, Hori M, Nakamura Y, and Tanaka T. . Association study in search for genetic backgrounds of myocardial infarction, focused on SNPs in genes encoding molecules that belong to lymphotoxin-a signaling cascade. . ASHG 2006 2006.10

Ozaki K, Inoue K, Odashiro M, Nobuyoshi M, Nakamura Y, Tanaka T. . Identification of proteins that bind galectin-2, encoded by a gene associated with myocardial infarction using tandem affinity purification method. . ASHG 2005 2005.11

Tanaka T.. BioBank Japan: Toward Personalized Medicine. . NCI Symposium: International Harmonization of Biorepository Practices 2005.11

Tanaka T.. From SNPs to Disease Risk –Towards predictive and personalized medicine.. 3rd World Congress of Nephrology 2005.06

Tanaka T.. Towards Personalized Medicine.. HUGO's 10th Human Genome Meeting (HGM2005) 2005.04

Tanaka T.. Recent Advance in Genomics for Diagnosis and Treatment of Cardiovascular Diseases.. The 69th Annual Science Meeting of the Japanese Circulation Society 2005.03

Tanaka T.. Functional variations in two genes encoding functionally associated proteins, lymphotoxin-α and galectin-2, confer risk of myocardial infarction.. The 13th Takeda Science Foundation Symposium on Bioscience 2004.12

Tanaka T.. The Japanese Biobank.. ESHG 2004 2004.06

Ozaki K, Ohnishi Y, Iida A, Yamada R, Tsunoda T, Sato H, Sato H, Hori M, Nakamura Y, Tanaka T. . Functional SNPs in the lymphotoxin- gene that are associated with susceptibility to myocardial infarction. . ASHG 2003 2003.11

Tanaka T.. Genome-wide association study identifies functional SNPs in the lymphotoxin- gene as associated with susceptibility to myocardial infarction.. Mendel Symposium 2003.08

Ozaki K, Ohnishi Y, Iida A, Yamada R, Tsunoda T, Sato H, Sato H, Hori M, Nakamura Y, Tanaka T. . Functional SNPs in the lymphotoxin- gene that are associated with susceptibility to myocardial infarction. . 3rd World Congress on Heart Disease 2003.07

Tanaka T, Tsukada S, Iwai M, Nishiu J, Itoh M, Tomoike H, Horiuchi M, Nakamura Y. . Inhibition of experimental intimal thickening in mice lacking a novel G-protein-coupled receptor. . 3rd World Congress on Heart Disease 2003.07

Tanaka T.. SNP projects in Japan. . The 5th International Workshop on Advanced Genomics 2003.06

Ohnishi Y, Tanaka T, Ozaki K, Sekine A, Nakamura Y. . A high-throughput SNP typing system for genome-wide association studies in patients with myocardial infarction. . ASHG 2002 2002.10

Ozaki K, Ohnishi Y, Iida A, Yamada R, Tsunoda T, Sekine A, Sato H, Sato H, Hori M, Nakamura Y, Tanaka T. . Genome-wide association study to identify genes related to myocardial infarction. . ASHG 2002 2002.10

Tanaka T.. SNP projects in Japan. . Osong International Symposium 2002.09

Tanaka T.. SNP projects in Japan. . Medical Genomics in Asia 2002.01

Inoue K, Tanaka T, Itoh M, Tomoike H, Yonekura K, Aoyagi T, Nagai R, Hori M, Nakamura Y.. Male-specific sudden cardiac death in mice with deficiency of a novel gene (OSR) related to ozidative stress resistance. . 第65回日本循環器学会・学術集会 2001.03

Yamada R, Tanaka T, Ohnishi Y, Yamamoto K, Nakamura Y. . An efficient SNP discovery procedure used in our association studies of rheumatoid arthritis. . ASHG 2000 2000.10

Tanaka T, Ohnishi Y, Yamada R, Nakamura Y. . Large-scale SNP (single nucleotide polymorphism) discovery project in Japan. . ASHG 2000 2000.10

Ohnishi Y, Tanaka T, Yamada R, Hori M, Nakamura Y. . Systematic survey of SNPs (single nucleotide polymorphisms) in the candidate responsible genes for myocardial infarction in the Japanese population.. ASHG 2000 2000.10

Tanaka T.. Microarray Analysis of Human Cancer; Toward Personalized Medicine.. Topic from Human Genome Project 2000.01

Ono K, Tanaka T, Kitahara O, Shiraishi N, Kihara C, Seki T, Yanagawa R, Ogasawara H, Okamoto T, Ohnishi Y, Kuzuya K, Tsunoda T, Takagi T, Nakamura Y.. Gene expression profiles of ovarian cancer using T7 based RNA amplification and cDNA microarray technology. . ASHG 1999 1999.10

Kihara C, Tanaka T, Furukawa Y, Ono K, Kitahara O, Shiraishi N, Yanagawa R, Ogasawara H, Seki T, Yamana H, Tsunoda T, Hirata K, Takagi T, Nakamura Y. . Gene expression profiles of esophageal cancer patients using cDNA microarray technology.. ASHG 1999 1999.10

Tanaka T, Ito T, Nagai R, Yazaki Y, Nakamura Y. . Mutational analysis of familiar long QT syndrome in Japan. . The 15th Annual Meeting of the Japanese Section 1998.12

Tanaka T, Itoh T, Nagai R, Yazaki Y, Nakamura Y. . Genomic organization of KVLQT1 and mutational analysis of familial long QT syndrome in Japan: further evidence for genotype/phenotype relationship. . ASHG 1998 1998.10

Tanaka T, Itoh T, Nagai R, Yazaki Y, Nakamura Y. . Mutational analysis of familial long QT syndrome; implication of correlation between mutated gene and response to beta-adrenergic blocking agent.. ASHG 1997 1997.10

Tanaka T, Nakamura Y. . Genetic analysis of long QT syndrome in Japan. . International Symposium on potassium ion channels; their molecular structure, function and diseases 1997.09

Tanaka T.. Genetic analysis of long QT syndrome in Japan. . International Symposium on potassium ion channels; their molecular structure, function and diseases. 1997.09

Tanaka T, Itoh M, Tsukada S, Orita T, Nishiu J, Tomoike H, Nakamura Y. . Isolation and characterization of novel genes related to endothelial proliferation by differential display method. . HUGO's Human Genome Meeting 1997.03

Tanaka T, Itoh M, Tsukada S, Orita T, Tomoike H, Nakamura Y. . Isolation of novel genes related to endothelial proliferation by differential mRNA display method.. ASHG 1996 1996.10

Tanaka T, Ogiwara A, Uchiyama I, Takagi T, Nakamura Y. . Construction of a normalized directionally-cloned cDNA library from adult heart and analysis of 3040 clones by partial sequencing. . HGM 1996 1996.03

Tanaka T, Nakamura Y.. A large scale cDNA sequencing of a normalized directionally-cloned cDNA library from adult heart. . ASHG 1995 1995.10