Personnel Information

写真a

TANAKA Toshihiro


Job title

Professor

Laboratory Address

1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510 Japan

Laboratory Phone number

+81-35803-5230

Laboratory Fax number

+81-3-5803-5230

Mail Address

ttana.brc@tmd.ac.jp

Graduating School 【 display / non-display

  • The University of Tokyo, Faculty of Medicine, 1990.03, Graduated

Graduate School 【 display / non-display

  • The University of Tokyo, Graduate School, Division of Medical Sciences, Doctor's Course, 1996.03, Completed

Degree 【 display / non-display

  • MD, The University of Tokyo

Campus Career 【 display / non-display

  • 2014.10
    -
    2016.02
    Tokyo Medical and Dental University, Research and Industry-University Alliance Organization, Bioresource Research Center, Professor
  • 2013.04
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Advanced Therapeutic Sciences, Human Genetics and Disease Diversity, Professor
  • 2013.04
    -
    2014.09
    Tokyo Medical and Dental University, Joint Institutes for Education and Research, Bioresource Research Center, Professor
  • 2013.04
    -
    2017.03
    Tokyo Medical and Dental University, Research and Industry-University Alliance Organization, Bioresource Research Center, Professor
  • 2017.04
     
     
    Tokyo Medical and Dental University, Institute of Research, Research Facility Cluster, Bioresource Research Center, Professor

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Academic Society Affiliations 【 display / non-display

  • American Heart Association

  • American Society of Human Genetics

  • International Society for Heart Research

Research Areas 【 display / non-display

  • Human genetics

  • Cardiovascular medicine

 

Published Papers & Misc 【 display / non-display

  • Chisato Shimizu, Jihoon Kim, Hariklia Eleftherohorinou, Victoria J Wright, Long T Hoang, Adriana H Tremoulet, Alessandra Franco, Martin L Hibberd, Atsushi Takahashi, Michiaki Kubo, Kaoru Ito, Toshihiro Tanaka, Yoshihiro Onouchi, Lachlan J M Coin, Michael Levin, Jane C Burns, Hiroko Shike, . HLA-C variants associated with amino acid substitutions in the peptide binding groove influence susceptibility to Kawasaki disease. Hum. Immunol.. 2019.09; 80 (9): 731-738. ( PubMed, DOI )

  • Yusuke Ebana, Yihan Sun, Xiaoxi Yang, Taiju Watanabe, Satoru Makita, Kouichi Ozaki, Toshihiro Tanaka, Hirokuni Arai, Tetsushi Furukawa. Pathway analysis with genome-wide association study (GWAS) data detected the association of atrial fibrillation with the mTOR signaling pathway. Int J Cardiol Heart Vasc. 2019.09; 24 100383. ( PubMed, DOI )

  • Yujiro Nakano, Takanobu Yoshimoto, Ryo Watanabe, Masanori Murakami, Tatsuya Fukuda, Kazutaka Saito, Yasuhisa Fujii, Takumi Akashi, Toshihiro Tanaka, Tetsuya Yamada, Mitsuhide Naruse, Yoshihiro Ogawa. miRNA299 involvement in CYP11B2 expression in aldosterone-producing adenoma. Eur. J. Endocrinol.. 2019.07; 181 (1): 69-78. ( PubMed, DOI )

  • Kyaw Thiha, Yoichi Mashimo, Hiroyuki Suzuki, Hiromichi Hamada, Akira Hata, Toshiro Hara, Toshihiro Tanaka, Kaoru Ito, Yoshihiro Onouchi, . Investigation of novel variations of ORAI1 gene and their association with Kawasaki disease. J. Hum. Genet.. 2019.06; 64 (6): 511-519. ( PubMed, DOI )

  • Wataru Shimizu, Hisaki Makimoto, Kenichiro Yamagata, Tsukasa Kamakura, Mitsuru Wada, Koji Miyamoto, Yuko Inoue-Yamada, Hideo Okamura, Kohei Ishibashi, Takashi Noda, Satoshi Nagase, Aya Miyazaki, Heima Sakaguchi, Isao Shiraishi, Takeru Makiyama, Seiko Ohno, Hideki Itoh, Hiroshi Watanabe, Kenshi Hayashi, Masakazu Yamagishi, Hiroshi Morita, Masao Yoshinaga, Yoshiyasu Aizawa, Kengo Kusano, Yoshihiro Miyamoto, Shiro Kamakura, Satoshi Yasuda, Hisao Ogawa, Toshihiro Tanaka, Naotaka Sumitomo, Nobuhisa Hagiwara, Keiichi Fukuda, Satoshi Ogawa, Yoshifusa Aizawa, Naomasa Makita, Tohru Ohe, Minoru Horie, Takeshi Aiba. Association of Genetic and Clinical Aspects of Congenital Long QT Syndrome With Life-Threatening Arrhythmias in Japanese Patients. JAMA Cardiol. 2019.03; 4 (3): 246-254. ( PubMed, DOI )

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Books etc 【 display / non-display

  • Precision Medicine & Drug Development. 2018.09

  • Ozaki K, and Tanaka T. Genes and Cardiovascular Function. 2011 Genetic Background of Myocardial Infarction

  • Ozaki K, and Tanaka T. Methods in Molecular Medicine. 2006 Genome-wide association study to identify single-nucleotide polymorphisms conferring risk of myocardial infarction.

  • Tanaka T, and Nakamura Y. Current Topics in Membranes. 1999 Mutational analysis of familial long QT syndrome in Japan

Conference Activities & Talks 【 display / non-display

  • Toshihiro Tanaka. Genomic Medicine and Cardiovascular Diseases. 2017.06.28

  • Tanaka T. Exome Analyses of Long QT Syndrome. Symposium20 Annual Meeting of the Japanese Heart Rhythm Society 2016 2016.07.16 Sapporo Convention Center

  • Ozaki K, Morizono T, Tsunoda T, Kubo M, Tanaka T. Up-regulation of FLT1 by a novel functional SNP increases risk of coronary artery disease through an inflammatory activation. ICHG2016 2016.04.07

  • Kanai M, Okada Y, Muramatsu T, Suita N, Kawakami E, Iotchkova V, Soranzo N, Inazawa J, Tanaka T. Significant impact of miRNA–target gene networks on genetics of human complex traits. ICHG2016 2016.04.07

  • Kanai M, Tanaka T, Okada Y. Empirical estimation of genome-wide significance thresholds based on the 1000 Genomes Project dataset. ICHG2016 2016.04.07

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Others 【 display / non-display

  • Tanaka T. Chairs,2016.04

    Complex traits and polygenic disorders2.
    Concurrent Oral Session 20.
    ICHG2016