Personnel Information

写真a

TANAKA Toshihiro


Job title

Professor

Laboratory Address

1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510 Japan

Laboratory Phone number

+81-35803-5230

Laboratory Fax number

+81-3-5803-5230

Mail Address

ttana.brc@tmd.ac.jp

Graduating School 【 display / non-display

  • The University of Tokyo, Faculty of Medicine, 1990.03, Graduated

Graduate School 【 display / non-display

  • The University of Tokyo, Graduate School, Division of Medical Sciences, Doctor's Course, 1996.03, Completed

Degree 【 display / non-display

  • MD, The University of Tokyo

Campus Career 【 display / non-display

  • 2013.04
    -
    2014.09
    Tokyo Medical and Dental University, Joint Institutes for Education and Research, Bioresource Research Center, Professor
  • 2013.04
    -
    2017.03
    Tokyo Medical and Dental University, Research and Industry-University Alliance Organization, Bioresource Research Center, Professor
  • 2013.04
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Advanced Therapeutic Sciences, Human Genetics and Disease Diversity, Professor
  • 2014.10
    -
    2016.02
    Tokyo Medical and Dental University, Research and Industry-University Alliance Organization, Bioresource Research Center, Professor
  • 2017.04
     
     
    Tokyo Medical and Dental University, Institute of Research, Research Facility Cluster, Bioresource Research Center, Professor

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Academic Society Affiliations 【 display / non-display

  • American Heart Association

  • American Society of Human Genetics

  • International Society for Heart Research

Research Areas 【 display / non-display

  • Human genetics

  • Cardiovascular medicine

 

Published Papers & Misc 【 display / non-display

  • Todd A Johnson, Yoichi Mashimo, Jer-Yuarn Wu, Dankyu Yoon, Akira Hata, Michiaki Kubo, Atsushi Takahashi, Tatsuhiko Tsunoda, Kouichi Ozaki, Toshihiro Tanaka, Kaoru Ito, Hiroyuki Suzuki, Hiromichi Hamada, Tohru Kobayashi, Toshiro Hara, Chien-Hsiun Chen, Yi-Ching Lee, Yi-Min Liu, Li-Ching Chang, Chun-Ping Chang, Young-Mi Hong, Gi-Young Jang, Sin-Weon Yun, Jeong-Jin Yu, Kyung-Yil Lee, Jae-Jung Kim, Taesung Park, , Jong-Keuk Lee, Yuan-Tsong Chen, Yoshihiro Onouchi. Association of an IGHV3-66 gene variant with Kawasaki disease. J Hum Genet. 2020.10; ( PubMed, DOI )

  • Kazuyoshi Ishigaki, Masato Akiyama, Masahiro Kanai, Atsushi Takahashi, Eiryo Kawakami, Hiroki Sugishita, Saori Sakaue, Nana Matoba, Siew-Kee Low, Yukinori Okada, Chikashi Terao, Tiffany Amariuta, Steven Gazal, Yuta Kochi, Momoko Horikoshi, Ken Suzuki, Kaoru Ito, Satoshi Koyama, Kouichi Ozaki, Shumpei Niida, Yasushi Sakata, Yasuhiko Sakata, Takashi Kohno, Kouya Shiraishi, Yukihide Momozawa, Makoto Hirata, Koichi Matsuda, Masashi Ikeda, Nakao Iwata, Shiro Ikegawa, Ikuyo Kou, Toshihiro Tanaka, Hidewaki Nakagawa, Akari Suzuki, Tomomitsu Hirota, Mayumi Tamari, Kazuaki Chayama, Daiki Miki, Masaki Mori, Satoshi Nagayama, Yataro Daigo, Yoshio Miki, Toyomasa Katagiri, Osamu Ogawa, Wataru Obara, Hidemi Ito, Teruhiko Yoshida, Issei Imoto, Takashi Takahashi, Chizu Tanikawa, Takao Suzuki, Nobuaki Sinozaki, Shiro Minami, Hiroki Yamaguchi, Satoshi Asai, Yasuo Takahashi, Ken Yamaji, Kazuhisa Takahashi, Tomoaki Fujioka, Ryo Takata, Hideki Yanai, Akihide Masumoto, Yukihiro Koretsune, Hiromu Kutsumi, Masahiko Higashiyama, Shigeo Murayama, Naoko Minegishi, Kichiya Suzuki, Kozo Tanno, Atsushi Shimizu, Taiki Yamaji, Motoki Iwasaki, Norie Sawada, Hirokazu Uemura, Keitaro Tanaka, Mariko Naito, Makoto Sasaki, Kenji Wakai, Shoichiro Tsugane, Masayuki Yamamoto, Kazuhiko Yamamoto, Yoshinori Murakami, Yusuke Nakamura, Soumya Raychaudhuri, Johji Inazawa, Toshimasa Yamauchi, Takashi Kadowaki, Michiaki Kubo, Yoichiro Kamatani. Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Nat Genet. 2020.07; 52 (7): 669-679. ( PubMed, DOI )

  • Yoshiki Higashijima, Yusuke Matsui, Teppei Shimamura, Ryo Nakaki, Nao Nagai, Shuichi Tsutsumi, Yohei Abe, Verena M Link, Mizuko Osaka, Masayuki Yoshida, Ryo Watanabe, Toshihiro Tanaka, Akashi Taguchi, Mai Miura, Xiaoan Ruan, Guoliang Li, Tsuyoshi Inoue, Masaomi Nangaku, Hiroshi Kimura, Tetsushi Furukawa, Hiroyuki Aburatani, Youichiro Wada, Yijun Ruan, Christopher K Glass, Yasuharu Kanki. Coordinated demethylation of H3K9 and H3K27 is required for rapid inflammatory responses of endothelial cells. EMBO J. 2020.04; 39 (7): e103949. ( PubMed, DOI )

  • Kyaw Thiha, Yoichi Mashimo, Hiroyuki Suzuki, Hiromichi Hamada, Akira Hata, Toshiro Hara, Toshihiro Tanaka, Kaoru Ito, Yoshihiro Onouchi, . Correction to: Investigation of novel variations of ORAI1 gene and their association with Kawasaki disease. J Hum Genet. 2019.10; 64 (10): 1049. ( PubMed, DOI )

  • Chisato Shimizu, Jihoon Kim, Hariklia Eleftherohorinou, Victoria J Wright, Long T Hoang, Adriana H Tremoulet, Alessandra Franco, Martin L Hibberd, Atsushi Takahashi, Michiaki Kubo, Kaoru Ito, Toshihiro Tanaka, Yoshihiro Onouchi, Lachlan J M Coin, Michael Levin, Jane C Burns, Hiroko Shike, . HLA-C variants associated with amino acid substitutions in the peptide binding groove influence susceptibility to Kawasaki disease. Hum. Immunol.. 2019.09; 80 (9): 731-738. ( PubMed, DOI )

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Books etc 【 display / non-display

  • Precision Medicine & Drug Development. 2018.09

  • Ozaki K, and Tanaka T. Genes and Cardiovascular Function. 2011 Genetic Background of Myocardial Infarction

  • Ozaki K, and Tanaka T. Methods in Molecular Medicine. 2006 Genome-wide association study to identify single-nucleotide polymorphisms conferring risk of myocardial infarction.

  • Tanaka T, and Nakamura Y. Current Topics in Membranes. 1999 Mutational analysis of familial long QT syndrome in Japan

Conference Activities & Talks 【 display / non-display

  • Toshihiro Tanaka. Genomic Medicine and Cardiovascular Diseases. 2017.06.28

  • Tanaka T. Exome Analyses of Long QT Syndrome. Symposium20 Annual Meeting of the Japanese Heart Rhythm Society 2016 2016.07.16 Sapporo Convention Center

  • Ozaki K, Morizono T, Tsunoda T, Kubo M, Tanaka T. Up-regulation of FLT1 by a novel functional SNP increases risk of coronary artery disease through an inflammatory activation. ICHG2016 2016.04.07

  • Kanai M, Okada Y, Muramatsu T, Suita N, Kawakami E, Iotchkova V, Soranzo N, Inazawa J, Tanaka T. Significant impact of miRNA–target gene networks on genetics of human complex traits. ICHG2016 2016.04.07

  • Kanai M, Tanaka T, Okada Y. Empirical estimation of genome-wide significance thresholds based on the 1000 Genomes Project dataset. ICHG2016 2016.04.07

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Others 【 display / non-display

  • Tanaka T. Chairs,2016.04

    Complex traits and polygenic disorders2.
    Concurrent Oral Session 20.
    ICHG2016