Personnel Information

写真a

HASEGAWA Hisanori


Job title

Junior Associate Professor

Birth date

1979

Mail Address

hasegawa.rheu@tmd.ac.jp

Graduating School 【 display / non-display

  • The University of Tokyo, Faculty of Education, 2000.03, Graduated

  • The University of Tokyo, Faculty of Pharmaceutical Science, 2002.03, Graduated

  • Tokyo Medical and Dental University, Faculty of Medicine, 2006.03, Graduated

Graduate School 【 display / non-display

  • Tokyo Medical and Dental University, Graduate School, Division of Medical Sciences, Doctor's Course, 2016.03, Completed

Campus Career 【 display / non-display

  • 2008.04
    -
    2009.03
    Tokyo Medical and Dental University, (Old Organization)Medical Hospital, Hospital Departments, Department of Internal Medicine, Rheumatology, Resident
  • 2010.04
    -
    2016.02
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Environmental Response, Rheumatology, Graduate Student
  • 2010.04
    -
    2016.03
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Environmental Response, Rheumatology, Graduate Student
  • 2011.07
    -
    2012.03
    Tokyo Medical and Dental University, (Old Organization)Medical Hospital, Hospital Departments, Department of Internal Medicine, Rheumatology, Assistant Professor
  • 2013.04
    -
    2014.03
    Tokyo Medical and Dental University, (Old Organization)Medical Hospital, Hospital Departments, Department of Internal Medicine, Rheumatology, Project Assistant Professor
  • 2017.04
    -
    2019.10
    Tokyo Medical and Dental University, (Old Organization)Medical Hospital, Hospital Departments, Department of Internal Medicine, Rheumatology, Assistant Professor
  • 2017.04
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Environmental Response, Rheumatology, Assistant Professor
  • 2017.04
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Environmental Response, Rheumatology, Assistant Professor
  • 2019.11
    -
    2021.03
    Tokyo Medical and Dental University, (Old Organization)Medical Hospital, Hospital Departments, Department of Internal Medicine, Rheumatology, Assistant Professor
  • 2021.04
    -
    2021.09
    Tokyo Medical and Dental University, (Old Organization)Medical Hospital, Hospital Departments, Department of Internal Medicine, Rheumatology, Junior Associate Professor
  • 2021.10
    -
    2022.12
    Tokyo Medical and Dental University, Tokyo Medical and Dental University, Division of Clinical Medicine, Department of Internal Medicine, Rheumatology, Junior Associate Professor
  • 2023.01
    -
    Now
    Tokyo Medical and Dental University, Institute of Global Affairs, Institute of Global Affairs Administrative Division , Junior Associate Professor

▼display all

External Career 【 display / non-display

  • 2006.04
    -
    2007.03
    , Trainee Resident
  • 2007.04
    -
    2008.03
    , Trainee Resident
  • 2009.04
    -
    2010.03
    , Senior Resident

Research Areas 【 display / non-display

  • Connective tissue disease and allergy

Qualification Acquired 【 display / non-display

  • Doctor

  • Pharmacist

 

Research Theme 【 display / non-display

  • Direct suppression of autoaggressive CD8+ T cells with CD80/86 blockade in CD8+ T cell-mediated polymyositis models of mice.

Published Papers & Misc 【 display / non-display

  1. Noda S, Honda S, Hirota Y, Ito T, Hasegawa H, Kimura N, Matsuo Y, Iwai H, Kohsaka H, Yasuda S. Azathioprine Monotherapy for the Cases of Immunoglobulin G4-Related Disease With Contraindications to Glucocorticoids. Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases. 2021.02; ( PubMed, DOI )

  2. Tanaka Yoshiya, Kuwana Masataka, Fujii Takao, Kameda Hideto, Muro Yoshinao, Fujio Keishi, Itoh Yasuhiko, Yasuoka Hidekata, Fukaya Shusaku, Ashihara Konomi, Hirano Daisuke, Ohmura Koichiro, Tabuchi Yuya, Hasegawa Hisanori, Matsumiya Ryo, Shirai Yuichiro, Ogura Takehisa, Tsuchida Yumi, Ogawa-Momohara Mariko, Narazaki Hidehiko, Inoue Yoshino, Miyagawa Ippei, Nakano Kazuhisa, Hirata Shintaro, Mori Masaaki, the Japan research committee of the ministry of health,labor,and welfare for systemic autoimmune diseases. 2019 Diagnostic criteria for mixed connective tissue disease(MCTD): From the Japan research committee of the ministry of health, labor, and welfare for systemic autoimmune diseases(和訳中) Modern Rheumatology. 2021.01; 31 (1): 29-33. ( ichushi )

  3. Tanaka Yoshiya, Kuwana Masataka, Fujii Takao, Kameda Hideto, Muro Yoshinao, Fujio Keishi, Itoh Yasuhiko, Yasuoka Hidekata, Fukaya Shusaku, Ashihara Konomi, Hirano Daisuke, Ohmura Koichiro, Tabuchi Yuya, Hasegawa Hisanori, Matsumiya Ryo, Shirai Yuichiro, Ogura Takehisa, Tsuchida Yumi, Ogawa-Momohara Mariko, Narazaki Hidehiko, Inoue Yoshino, Miyagawa Ippei, Nakano Kazuhisa, Hirata Shintaro, Mori Masaaki. 2019 Diagnostic criteria for mixed connective tissue disease (MCTD): From the Japan research committee of the ministry of health, labor, and welfare for systemic autoimmune diseases MODERN RHEUMATOLOGY. 2021.01; 31 (1): 29-33. ( PubMed, DOI )

  4. Noda S, Hasegawa H, Tokura M, Mizoguchi F, Kohsaka H. A Case of Systemic Lupus Erythematosus Presenting With Thrombotic Microangiopathy-Induced Cardiomyopathy. Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases. 2020.02; ( PubMed, DOI )

  5. Okumura Takashi, Horie Yumi, Lai Chen-Yi, Lin Huan-Ting, Shoda Hirofumi, Natsumoto Bunki, Fujio Keishi, Kumaki Eri, Okano Tsubasa, Ono Shintaro, Tanita Kay, Morio Tomohiro, Kanegane Hirokazu, Hasegawa Hisanori, Mizoguchi Fumitaka, Kawahata Kimito, Kohsaka Hitoshi, Moritake Hiroshi, Nunoi Hiroyuki, Waki Hironori, Tamaru Shin-ichi, Sasako Takayoshi, Yamauchi Toshimasa, Kadowaki Takashi, Tanaka Hiroyuki, Kitanaka Sachiko, Nishimura Ken, Ohtaka Manami, Nakanishi Mahito, Otsu Makoto. Robust and highly efficient hiPSC generation from patient non-mobilized peripheral blood-derived CD34(+) cells using the auto-erasable Sendai virus vector STEM CELL RESEARCH & THERAPY. 2019.06; 10 (1): 185. ( PubMed, DOI )

  6. Honda Suguru, Hirano Fumio, Mouri Mariko, Hasegawa Hisanori, Kohsaka Hitoshi. Aneurysm formation after stent grafting in vascular Behcet's disease ARTHRITIS & RHEUMATOLOGY. 2018.02; 70 (2): 322. ( PubMed, DOI )

  7. Hisanori Hasegawa, Kimito Kawahata, Fumitaka Mizoguchi, Naoko Okiyama, Nobuyuki Miyasaka, Hitoshi Kohsaka. Direct suppression of autoaggressive CD8+ T cells with CD80/86 blockade in CD8+ T cell-mediated polymyositis models of mice. Clin. Exp. Rheumatol.. 2017.07; 35 (4): 593-597. ( PubMed )

  8. Hosoya Tadashi, Mizoguchi Fumitaka, Hasegawa Hisanori, Miura Keiko, Koike Ryuji, Kubota Tetsuo, Miyasaka Nobuyuki, Kohsaka Hitoshi. TNFRSF1A遺伝子変異を認めず、トシリズマブ投与が奏効した、腫瘍壊死因子(TNF)受容体関連周期性症候群(TRAPS)の臨床的特徴を示す1症例(A Case Presenting with the Clinical Characteristics of Tumor Necrosis Factor(TNF) Receptor-associated Periodic Syndrome(TRAPS) without TNFRSF1A Mutations Successfully Treated with Tocilizumab) Internal Medicine. 2015.08; 54 (16): 2069-2072. ( ichushi )

  9. Okiyama Naoko, Hasegawa Hisanori, Oida Takatoku, Hirata Shinya, Yokozeki Hiroo, Fujimoto Manabu, Miyasaka Nobuyuki, Kohsaka Hitoshi. Experimental myositis inducible with transfer of dendritic cells presenting a skeletal muscle C protein-derived CD8 epitope peptide INTERNATIONAL IMMUNOLOGY. 2015.07; 27 (7): 327-332. ( PubMed, DOI )

  10. Hosoya Tadashi, Mizoguchi Fumitaka, Hasegawa Hisanori, Miura Keiko, Koike Ryuji, Kubota Tetsuo, Miyasaka Nobuyuki, Kohsaka Hitoshi. A Case Presenting with the Clinical Characteristics of Tumor Necrosis Factor (TNF) Receptor-associated Periodic Syndrome (TRAPS) without TNFRSF1A Mutations Successfully Treated with Tocilizumab INTERNAL MEDICINE. 2015; 54 (16): 2069-2072. ( PubMed, DOI )

  11. Fukuda Shin, Nanki Toshihiro, Morio Tomohiro, Hasegawa Hisanori, Koike Ryuji, Miyasaka Nobuyuki. Recurrent mitral valve regurgitation with neutrophil infiltration in a patient with multiple aseptic abscesses MODERN RHEUMATOLOGY. 2014.05; 24 (3): 537-539. ( PubMed, DOI )

  12. Hasegawa H., Mizoguchi F., Kohsaka H., Miyasaka N.. Systemic lupus erythematosus with cytophagic histiocytic panniculitis successfully treated with high-dose glucocorticoids and cyclosporine A LUPUS. 2013.03; 22 (3): 316-319. ( DOI )

  13. Hasegawa Hisanori, Kohsaka Hitoshi, Takada Kazuki, Miyasaka Nobuyuki. Renal Involvement in Antimyeloperoxidase Antineutrophil Cytoplasmic Antibody-positive Granulomatosis with Polyangiitis with Chronic Hypertrophic Pachymeningitis JOURNAL OF RHEUMATOLOGY. 2012.10; 39 (10): 2053-2055. ( PubMed, DOI )

  14. Hasegawa H, Fukushima T, Lee JA, Tsukamoto K, Moriya K, Ono Y, Imai K.. Determination of serum D-lactic and L-lactic acids in normal subjects and diabetic patients by column-switching HPLC with pre-column fluorescence derivatization. Analytical and Bioanalytical Chemistry. 2003.11; 377 886-891.

  15. Hashimoto K, Fukushima T, Shimizu E, Komatsu N, Watanabe H, Shinoda N, Nakazato M, Kumakiri C, Okada S, Hasegawa H, Imai K, Iyo M.. Decreased serum levels of D-serine in patients with schizophrenia: evidence in support of the N-methyl-D-aspartate receptor hypofunction hypothesis of schizophrenia. Archives of General Psychiatry. 2003.06; 60 572-576.

▼display all

Conference Activities & Talks 【 display / non-display

  1. Mizoguchi Fumitaka, Hasegawa Hisanori, Kohsaka Hitoshi. Functional Screening of Micrornas Using the Inhibitor Library Identified Micrornas to Regulate Expression of MMP-3 and IL-6 in Rheumatoid Arthritis Synovial Fibroblasts. 2016 American College of Rheumatology 2016.11.16

  2. Okiyama Naoko, Hasegawa HIsanori, Oida Takatoku, Hirata Shinya, Yokozeki Hiroo, Fujimoto Manabu, Kohsaka Hitoshi. 臓器特異的自己免疫疾患(2) 骨格筋C蛋白由来CD8Tエピトープペプチドを提示する樹状細胞の移入により誘発可能は実験的筋炎. 第44回(2015年)日本免疫学会学術集会 2015.11.19

  3. Naoko Okiyama, Hisanori Hasegawa, Takamori Oida, Sinya Hirata,Hiroo Yokozeki, Manabu Fujimoto, Nobuyuki Miyasaka, Hitoshi Kohsaka.. Experimental Myositis Inducible with Transfer of Dendritic Cells Presenting a Skeletal Muscle C protein-derived CD8 Epitope Peptide.. 1st International Conference on Myositis 2015.05.08 Stockholm, Sweden

  4. Hisanori Hasegawa, Fumitaka Mizoguchi, Naoko Okiyama, Miyuki Azuma, Nobuyuki Miyaksaka, Hitoshi Kohsaka. . 6. CD28-CD80/86 blockade by CTLA-4Ig suppresses murine models of polymyositis driven by cytotoxic CD8 T cells. . The 5th East Asian Group of Rheumatology 2013.06.01

Awards & Honors 【 display / non-display

  • Young investigator award,East Asian Group of Rheumatology,2013.05

 

Performance of duties 【 display / non-display

  • ,2016.04 - Now