Ryo Nakamichi, Hiroshi Asahara. Motion-capture Analysis of Mice Using a Video Recorded on an iPhone Camera. Bio Protoc. 2022.11; 12 (21): ( PubMed, DOI )

Tomohiko Murakami, Yoshifumi Takahata, Kenji Hata, Kosuke Ebina, Katsutoshi Hirose, Lerdluck Ruengsinpinya, Yuri Nakaminami, Yuki Etani, Sachi Kobayashi, Takashi Maruyama, Hiroyasu Nakano, Takehito Kaneko, Satoru Toyosawa, Hiroshi Asahara, Riko Nishimura. Semaphorin 4D induces articular cartilage destruction and inflammation in joints by transcriptionally reprogramming chondrocytes. Sci Signal. 2022.11; 15 (758): eabl5304. ( PubMed, DOI )

Takayoshi Sasako, Toshihiro Umehara, Kotaro Soeda, Kazuma Kaneko, Miho Suzuki, Naoki Kobayashi, Yukiko Okazaki, Miwa Tamura-Nakano, Tomoki Chiba, Domenico Accili, C Ronald Kahn, Tetsuo Noda, Hiroshi Asahara, Toshimasa Yamauchi, Takashi Kadowaki, Kohjiro Ueki. Deletion of skeletal muscle Akt1/2 causes osteosarcopenia and reduces lifespan in mice. Nat Commun. 2022.10; 13 (1): 5655. ( PubMed, DOI )

Ryo Nakamichi, Shang Ma, Takayuki Nonoyama, Tomoki Chiba, Ryota Kurimoto, Hiroki Ohzono, Merissa Olmer, Chisa Shukunami, Noriyuki Fuku, Guan Wang, Errol Morrison, Yannis P Pitsiladis, Toshifumi Ozaki, Darryl D'Lima, Martin Lotz, Ardem Patapoutian, Hiroshi Asahara. The mechanosensitive ion channel PIEZO1 is expressed in tendons and regulates physical performance. Sci Transl Med. 2022.06; 14 (647): eabj5557. ( PubMed, DOI )

Yuta Fujii, Lin Liu, Lisa Yagasaki, Maiko Inotsume, Tomoki Chiba, Hiroshi Asahara. Cartilage Homeostasis and Osteoarthritis. Int J Mol Sci. 2022.06; 23 (11): ( PubMed, DOI )

Manabu Kawata, Takeshi Teramura, Philip Ordoukhanian, Steven R Head, Padmaja Natarajan, Aishwarya Sundaresan, Merissa Olmer, Hiroshi Asahara, Martin K Lotz. Krüppel-like factor-4 and Krüppel-like factor-2 are important regulators of joint tissue cells and protect against tissue destruction and inflammation in osteoarthritis. Ann Rheum Dis. 2022.05; ( PubMed, DOI )

Kaho Takada, Tomoki Chiba, Takayuki Miyazaki, Lisa Yagasaki, Ryo Nakamichi, Takanori Iwata, Keiji Moriyama, Hiroyuki Harada, Hiroshi Asahara. Single Cell RNA Sequencing Reveals Critical Functions of Mkx in Periodontal Ligament Homeostasis Front Cell Dev Biol. 2022.02; 10 795441. ( PubMed, DOI )

Hiroki Tsutsumi, Ryota Kurimoto, Ryo Nakamichi, Tomoki Chiba, Takahide Matsushima, Yuta Fujii, Risa Sanada, Tomomi Kato, Kana Shishido, Yuriko Sakamaki, Tsuyoshi Kimura, Akio Kishida, Hiroshi Asahara. Generation of a tendon-like tissue from human iPS cells. J Tissue Eng. 2022.01; 13 20417314221074018. ( PubMed, DOI )

Yoshiaki Ito, Tokio Matsuzaki, Fumiaki Ayabe, Sho Mokuda, Ryota Kurimoto, Takahide Matsushima, Yusuke Tabata, Maiko Inotsume, Hiroki Tsutsumi, Lin Liu, Masahiro Shinohara, Yoko Tanaka, Ryo Nakamichi, Keiichiro Nishida, Martin K Lotz, Hiroshi Asahara. Both microRNA-455-5p and -3p repress hypoxia-inducible factor-2α expression and coordinately regulate cartilage homeostasis. Nat Commun. 2021.07; 12 (1): 4148. ( PubMed, DOI )

Takayuki Miyazaki, Ryota Kurimoto, Tomoki Chiba, Takahide Matsushima, Ryo Nakamichi, Hiroki Tsutsumi, Kaho Takada, Lisa Yagasaki, Tomomi Kato, Kana Shishido, Yukiho Kobayashi, Tsutomu Matsumoto, Keiji Moriyama, Hiroshi Asahara. Mkx regulates the orthodontic tooth movement via osteoclast induction. J Bone Miner Metab. 2021.05; 39 (5): 780-786. ( PubMed, DOI )

Yutaro Uchida, Takahide Matsushima, Ryota Kurimoto, Tomoki Chiba, Yuki Inutani, Hiroshi Asahara. Identification of chemical compounds regulating PD-L1 by introducing HiBiT-tagged cells. FEBS Lett. 2021.03; 595 (5): 563-576. ( PubMed, DOI )

Tomoki Chiba, Ryota Kurimoto, Takahide Matsushima, Yoshiaki Ito, Ryo Nakamichi, Martin Lotz, Hiroshi Asahara. MicroRNA Expression Profiling, Target Identification, and Validation in Chondrocytes. Methods Mol Biol. 2021; 2245 151-166. ( PubMed, DOI )

Keiko Itano,KojiOchiai, Takahide Matsushima,Hiroshi Asahara and Koichi Takahashi. Automation of Foci-Cell-State Judgement with Regression Models Transactions of the Institute of Systems, Control and Information Engineers. 2021; 34 (3): 69-80. ( DOI )

Ryota Kurimoto, Tomoki Chiba, Yoshiaki Ito, Takahide Matsushima, Yuki Yano, Kohei Miyata, Yuka Yashiro, Tsutomu Suzuki, Kozo Tomita, Hiroshi Asahara. The tRNA pseudouridine synthase TruB1 regulates the maturation of let-7 miRNA. EMBO J. 2020.10; 39 (20): e104708. ( PubMed, DOI )

Kwang Il Lee, Ramya Gamini, Merissa Olmer, Yasunari Ikuta, Joe Hasei, Jihye Baek, Oscar Alvarez-Garcia, Shawn P Grogan, Darryl D D'Lima, Hiroshi Asahara, Andrew I Su, Martin K Lotz. Mohawk is a transcription factor that promotes meniscus cell phenotype and tissue repair and reduces osteoarthritis severity. Sci Transl Med. 2020.10; 12 (567): 7967. ( PubMed, DOI )

Ryo Nakamichi, Ryota Kurimoto, Yusuke Tabata, Hirosi Asahara. Transcriptional, epigenetic and microRNA regulation of growth plate. Bone. 2020.08; 137 115434. ( PubMed, DOI )

Ryo Nakamichi, Hiroshi Asahara. Regulation of tendon and ligament differentiation. Bone. 2020.08; 115609. ( PubMed, DOI )

Mokuda S, Nakamichi R, Ito Y, Asahara H. Genetic, Epigenetic, and MicroRNA Regulation of Osteoarthritis Encyclopedia of Bone Biology, vol.[1]. 2020.06; 1 641-651.

Tempei Sato, Kensuke Kataoka, Yoshiaki Ito, Shigetoshi Yokoyama, Masafumi Inui, Masaki Mori, Satoru Takahashi, Keiichi Akita, Shuji Takada, Hiroe Ueno-Kudoh, Hiroshi Asahara. Lin28a/let-7 pathway modulates the Hox code via Polycomb regulation during axial patterning in vertebrates Elife. 2020.05; 9 ( PubMed, DOI )

Ryo Nakamichi, Hiroshi Asahara. The transcription factors regulating intervertebral disc development. JOR Spine. 2020.03; 3 (1): e1081. ( PubMed, DOI )

Eric Gracey, Arne Burssens, Isabelle Cambré, Georg Schett, Rik Lories, Iain B McInnes, Hiroshi Asahara, Dirk Elewaut. Tendon and ligament mechanical loading in the pathogenesis of inflammatory arthritis. Nat Rev Rheumatol. 2020.02; 16 (4): 193-207. ( PubMed, DOI )

Kensuke Kataoka, Ryota Kurimoto, Hiroki Tsutsumi, Tomoki Chiba, Tomomi Kato, Kana Shishido, Mariko Kato, Yoshiaki Ito, Yuichiro Cho, Osamu Hoshi, Ayako Mimata, Yuriko Sakamaki, Ryo Nakamichi, Martin K Lotz, Keiji Naruse, Hiroshi Asahara. In vitro Neo-Genesis of Tendon/Ligament-Like Tissue by Combination of Mohawk and a Three-Dimensional Cyclic Mechanical Stretch Culture System Front Cell Dev Biol. 2020; 8 307. ( PubMed, DOI )

Yuki Yano, Tomoki Chiba, Hiroshi Asahara. Analysis of the Mouse Y Chromosome by Single-Molecule Sequencing With Y Chromosome Enrichment. Front Genet. 2020; 11 406. ( PubMed, DOI )

Hiroto Yamamoto, Yutaro Uchida, Tomoki Chiba, Ryota Kurimoto, Takahide Matsushima, Maiko Inotsume, Chihiro Ishikawa, Haiyan Li, Takashi Shiga, Masafumi Muratani, Tokujiro Uchida, Hiroshi Asahara. Transcriptome analysis of sevoflurane exposure effects at the different brain regions. PLoS One. 2020; 15 (12): e0236771. ( PubMed, DOI )

Carmen Adriaens, Florian Rambow, Greet Bervoets, Toomas Silla, Mari Mito, Tomoki Chiba, Hiroshi Asahara, Tetsuro Hirose, Shinichi Nakagawa, Torben Heick Jensen, Jean-Christophe Marine. The long noncoding RNA NEAT1_1 is seemingly dispensable for normal tissue homeostasis and cancer cell growth. RNA. 2019.12; 25 (12): 1681-1695. ( PubMed, DOI )

Momo Isobe, Hikaru Toya, Mari Mito, Tomoki Chiba, Hiroshi Asahara, Tetsuro Hirose, Shinichi Nakagawa. Forced isoform switching of Neat1_1 to Neat1_2 leads to the loss of Neat1_1 and the hyperformation of paraspeckles but does not affect the development and growth of mice. RNA. 2019.12; ( PubMed, DOI )

Yutaro Uchida, Tomoki Chiba, Ryota Kurimoto, Hiroshi Asahara. Post-transcriptional regulation of inflammation by RNA-binding proteins via cis-elements of mRNAs. J. Biochem.. 2019.11; 166 (5): 375-382. ( PubMed, DOI )

Satoshi Yamashita, Kensuke Kataoka, Hiroto Yamamoto, Tomoko Kato, Satoshi Hara, Katsushi Yamaguchi, Claire Renard-Guillet, Yuki Katou, Katsuhiko Shirahige, Haruki Ochi, Hajime Ogino, Tokujiro Uchida, Masafumi Inui, Shuji Takada, Shuji Shigenobu, Hiroshi Asahara. Comparative analysis demonstrates cell type-specific conservation of SOX9 targets between mouse and chicken. Sci Rep. 2019.08; 9 (1): 12560. ( PubMed, DOI )

Kita M, Nakae J, Kawano Y, Asahara H, Takemori H, Okado H, Itoh H. Zfp238 Regulates the Thermogenic Program in Cooperation with Foxo1. iScience. 2019.02; 12 87-101. ( PubMed, DOI )

Takayoshi Sasako, Mitsuru Ohsugi, Naoto Kubota, Shinsuke Itoh, Yukiko Okazaki, Ai Terai, Tetsuya Kubota, Satoshi Yamashita, Kunio Nakatsukasa, Takumi Kamura, Kaito Iwayama, Kumpei Tokuyama, Hiroshi Kiyonari, Yasuhide Furuta, Junji Shibahara, Masashi Fukayama, Kenichiro Enooku, Kazuya Okushin, Takeya Tsutsumi, Ryosuke Tateishi, Kazuyuki Tobe, Hiroshi Asahara, Kazuhiko Koike, Takashi Kadowaki, Kohjiro Ueki. Hepatic Sdf2l1 controls feeding-induced ER stress and regulates metabolism. Nat Commun. 2019.02; 10 (1): 947. ( PubMed, DOI )

Mitsumura T, Ito Y, Chiba T, Matsushima T, Kurimoto R, Tanaka Y, Kato T, Uchida K, Ito T, Yamamoto K, Eishi Y, Kitagawa M, Miyazaki Y, Inase N, Asahara H. Ablation of miR-146b in mice causes hematopoietic malignancy Blood Advances. 2018.11; 2 (23): 3483-3491. ( PubMed, DOI )

Takeshi Saito, Satoshi Hara, Tomoko Kato, Moe Tamano, Akari Muramatsu, Hiroshi Asahara, Shuji Takada. A tandem repeat array in IG-DMR is essential for imprinting of paternal allele at the Dlk1-Dio3 domain during embryonic development. Hum. Mol. Genet.. 2018.09; 27 (18): 3283-3292. ( PubMed, DOI )

Yusuke Mochizuki, Tomoki Chiba, Kensuke Kataoka, Satoshi Yamashita, Tempei Sato, Tomomi Kato, Kenji Takahashi, Takeshi Miyamoto, Masashi Kitazawa, Tomohisa Hatta, Tohru Natsume, Shinro Takai, Hiroshi Asahara. Combinatorial CRISPR/Cas9 Approach to Elucidate a Far-Upstream Enhancer Complex for Tissue-Specific Sox9 Expression. Dev. Cell. 2018.08; 46 (6): 794-806.e6. ( PubMed, DOI )

Alvarez-Garcia O, Matsuzaki T, Olmer M, Miyata K, Mokuda S, Sakai D, Masuda K, Asahara H, Lotz MK. FOXO are required for intervertebral disk homeostasis during aging and their deficiency promotes disk degeneration. Aging Cell. 2018.07; e12800. ( PubMed, DOI )

Nakamichi R, Kataoka K, Asahara H. Essential role of Mohawk for tenogenic tissue homeostasis including spinal disc and periodontal ligament. Modern rheumatology. 2018.05; 1-8. ( PubMed, DOI )

Masafumi Inui, Sho Mokuda, Tempei Sato, Moe Tamano, Shuji Takada, Hiroshi Asahara. Dissecting the roles of miR-140 and its host gene. Nat. Cell Biol.. 2018.05; 20 (5): 516-518. ( PubMed, DOI )

Tokio Matsuzaki, Oscar Alvarez-Garcia, Sho Mokuda, Keita Nagira, Merissa Olmer, Ramya Gamini, Kohei Miyata, Yukio Akasaki, Andrew I Su, Hiroshi Asahara, Martin K Lotz. FoxO transcription factors modulate autophagy and proteoglycan 4 in cartilage homeostasis and osteoarthritis. Sci Transl Med. 2018.02; 10 (428): ( PubMed, DOI )

Kataoka K, Matsushima T, Ito Y, Sato T, Yokoyama S, Asahara H. Bhlha9 regulates apical ectodermal ridge formation during limb development. JBMM. 2018.01; 36 (1): 64-72. ( PubMed, DOI )

kuda K, Kobayashi S, Fukaya M, Watanabe A, Murakami T, Hagiwara M, Sato T, Ueno H, Ogonuki N, Komano-Inoue S, Manabe H, Yamaguchi M, Ogura A, Asahara H, Sakagami H, Mizuguchi M, Manabe T, Tanaka T. CDKL5 controls postsynaptic localization of GluN2B-containing NMDA receptors in the hippocampus and regulates seizure susceptibility. Neurobiol Dis. 2017.10; 106 158-170. ( PubMed, DOI )

Shiba D, Mizuno H, Yumoto A, Shimomura M, Kobayashi H, Morita H, Shimbo M, Hamada M, Kudo T, Shinohara M, Asahara H, Shirakawa M, Takahashi S.. Development of new experimental platform 'MARS'-Multiple Artificial-gravity Research System-to elucidate the impacts of micro/partial gravity on mice. Sci Rep. 2017.09; 7 (1): 10837. ( PubMed, DOI )

Asahara H*, Inui M*, Lotz M. Tendons and Ligaments: Connecting Developmental Biology to Musculoskeletal Disease Pathogenesis. JBMR. 2017.09; 32 (9): 1773-1782. ( PubMed )

Miyata K, Naito M, Miyata T, Mokuda S, Asahara H*. Bisulfite Sequencing for DNA Methylation Analysis of Primary Muscle Stem Cells. Methods Mol Biol. 2017.08; (1668): 3-13. ( PubMed )

Ogino H, Hisanaga A, Kohno T, Kondo Y, Okumura K, Kamei T, Sato T, Asahara H, Tsuiji H, Fukata M, Hattori M. Secreted Metalloproteinase ADAMTS-3 Inactivates Reelin. J Neurosci. 2017.05; 37 (12): 3181-3191. ( PubMed, DOI )

Oba A, Shimada S, Akiyama Y, Nishikawaji T, Mogushi K, Ito H, Matsumura S, Aihara A, Mitsunori Y, Ban D, Ochiai T, Kudo A, Asahara H, Kaida A, Miura M, Tanabe M, Tanaka S. ARID2 modulates DNA damage response in human hepatocellular carcinoma cells. J Hepato. 2017.05; 66 (5): 942-951. ( PubMed, DOI )

Yokoyama S, Furukawa S, Kitada S, Mori M, Saito T, Kawakami K, Izpisua Belmonte JC, Kawakami Y, Ito Y, Sato T, AsaharaH. Analysis of transcription factors expressed at the anterior mouse limb bud. PLoS One. 2017.05; 12 (5): e0175673. ( PubMed, DOI )

Ito Y, Inoue A, Seers T, Hato Y, Igarashi A, Toyama T, Taganov K, Boldin M, AsaharaH. Identification of targets of tumor suppressor microRNA-34a using a reporter library system. Proc Natl Acad Sci U S A. 2017.04; 114 (15): 3927-3932. ( PubMed, DOI )

Nozomu Yachie, Robotic Biology Consortium, Tohru Natsume. Robotic crowd biology with Maholo LabDroids. Nat. Biotechnol.. 2017.04; 35 (4): 310-312. ( PubMed, DOI )

Matsui-Hasumi A, Sato Y, Uto-Konomi A, Yamashita S, Uehori J, Yoshimura A, Yamashita M, Asahara H, Suzuki S, Kubo M. E3 ubiquitin ligases SIAH1/2 regulate hypoxia-inducible factor-1 (HIF-1)-mediated Th17 cell differentiation. International immunology. 2017.03; 29 (3): 133-143. ( PubMed, DOI )

Saito T, Hara S, Tamano M, Asahara H, Takada S. Deletion of conserved sequences in IG-DMR at Dlk1-Gtl2 locus suggests their involvement in expression of paternally expressed genes in mice. J Reprod Dev. 2017.02; 63 (1): 101-109. ( PubMed, DOI )

Hasei J, Teramura T, Takehara T, Onodera Y, Horii T, Olmer M, Hatada I, Fukuda K, Ozaki T, Lotz M, Asahara H. TWIST1 induces MMP3 expression through up-regulating DNA hydroxymethylation and promotes catabolic responses in human chondrocytes. Sci Rep. 2017.02; 7 42990. ( PubMed, DOI )

Nakasuji T, Ogonuki N, Chiba T, Kato T, Shiozawa K, Yamatoya K, Tanaka H, Kondo T, Miyado K, Miyasaka N, Kubota T, Ogura A, Asahara H. . Complementary critical functions of Zfy1 and Zfy2 in mouse spermatogenesis and reproductiontran PLoS Genetics. 2017.01; ( PubMed, DOI )

Koda N, Sato T, Shinohara M, Ichinose S, Ito Y, Nakamichi R, Kayama T, Kataoka K, Suzuki H, Moriyama K, Asahara H. The transcription factor mohawk homeobox regulates homeostasis of the periodontal ligament. Development (Cambridge, England). 2017.01; 144 (2): 313-320. ( PubMed, DOI )

Otero M, Peng H, El Hachem K, Culley KL, Wondimu EB, Quinn J, Asahara H, Tsuchimochi K, Hashimoto K, Goldring MB. ELF3 modulates type II collagen gene (COL2A1) transcription in chondrocytes by Inhibiting SOX9-CBP/p300-driven histone acetyltransferase activity. Connect Tissue Res. 2017.01; 58 (1): 15-26. ( PubMed, DOI )

Asahara H*.. Current Status and Strategy of microRNA Research for Cartilage Development and Osteoarthritis Pathogenesis. J Bone Metab. . 2016.08; 23 (3): 121-127. ( PubMed, DOI )

Ryo Nakamichi, Yoshiaki Ito, Masafumi Inui, Naoko Onizuka, Tomohiro Kayama, Kensuke Kataoka, Hidetsugu Suzuki, Masaki Mori, Masayo Inagawa, Shizuko Ichinose, Martin K Lotz, Daisuke Sakai, Koichi Masuda, Toshifumi Ozaki, Hiroshi Asahara. Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs. Nat Commun. 2016.08; 7 12503. ( PubMed, DOI )

Naito M, Mori M, Inagawa M, Miyata K, Hashimoto N, Tanaka S, Asahara H.. Dnmt3a Regulates Proliferation of Muscle Satellite Cells via p57Kip2. PLoS Genetics. . 2016.07; 12 (7): e1006167. ( PubMed, DOI )

Shimbo M, Kudo T, Hamada M, Jeon H, Imamura Y, Asano K, Okada R, Tsunakawa Y, Mizuno S, Yagami KI, Ishikawa C, Li H, Shiga T, Ishida J, Hamada J, Murata K, Ishimaru T, Hashimoto M, Fukamizu A, Yamane M, Ikawa M, Morita H, Shinohara M, Asahara H, Akiyama T, Akiyama N, Sasanuma H, Yoshida N, Zhou R, Wang YY, Ito T, Kokubu Y, Noguchi TK, Ishimine H, Kurisaki A, Shiba D, Mizuno H, Shirakawa M, Ito N, Takeda S, Takahashi S.. Ground-based assessment of JAXA mouse habitat cage unit by mouse phenotypic studies. Experimental Animals. 2016.05; ( PubMed, DOI )

Kayama T, Mori M, Ito Y, Matsushima T, Nakamichi R, Suzuki H, Ichinose S, Saito M, Marumo K, Asahara H.. Gtf2ird1-dependent Mohawk (Mkx) expression regulates mechanosensing properties of tendon. Mol Cell Biol. 2016.02; ( PubMed, DOI )

Doiguchi M, Nakagawa T, Imamura Y, Yoneda M, Higashi M, Kubota K, Yamashita S, Asahara H, Iida M, Fujii S, Ikura T, Liu Z, Nandu T, Kraus WL, Ueda H, Ito T. SMARCAD1 is an ATP-dependent stimulator of nucleosomal H2A acetylation via CBP, resulting in transcriptional regulation Sci Rep. 2016.02; ( PubMed, DOI )

Hidetsugu Suzuki, Yoshiaki Ito, Masahiro Shinohara, Satoshi Yamashita, Shizuko Ichinose, Akio Kishida, Takuya Oyaizu, Tomohiro Kayama, Ryo Nakamichi, Naoki Koda, Kazuyoshi Yagishita, Martin K Lotz, Atsushi Okawa, Hiroshi Asahara. Gene targeting of the transcription factor Mohawk in rats causes heterotopic ossification of Achilles tendon via failed tenogenesis. Proc. Natl. Acad. Sci. U.S.A.. 2016.01; 113 (28): 7840-7845. ( PubMed, DOI )

T. Chiba, Y. Ito, H. Asahara.. Post-Transcriptional Gene Regulation by MicroRNA and RNA-Binding Protein Biomedical Sciences. 2016;

Ito Y, Mokuda S, Miyata K, Matsushima T, Asahara H.. MicroRNAs in Chronic Inflammation Diseases. Chronic Inflammation (Chapter 6) 2016 Springer Japan. Review. Book.. 2016; ( DOI )

Ogura Y, Miyake N, Kou I, Iida A, Nakajima M, Takeda K, Fujibayashi S, Shiina M, Okada E, Toyama Y, Iwanami A, Ishii K, Ogata K, Asahara H, Matsumoto N, Nakamura M, Matsumoto M, Ikegawa S. Identification of HOXD4 Mutations in Spinal Extradural Arachnoid Cyst PLoS One. 2015.11; ( PubMed, DOI )

Ryosuke Tateishi , Nobuko Akiyama , Maki Miyauchi, Riko Yoshinaga, Hiroki Sasanuma, Takashi Kudo, Miki Shimbo, Masahiro Shinohara, Koji Obata, Jun-ichiro Inoue, Masaki Shirakawa, Dai Shiba, Hiroshi Asahara, Nobuaki Yoshida, Satoru Takahashi, Hironobu Morita , Taishin Akiyama. Hypergravity Provokes a Temporary Reduction in CD4+CD8+ Thymocyte Number and a Persistent Decrease in Medullary Thymic Epithelial Cell Frequency in Mice. PLoS One. 2015.10; 10 ( PubMed, DOI )

Gernapudi R, Wolfson B, Zhang Y, Yao Y, Yang P, Asahara H, Zhou Q. MicroRNA 140 Promotes Expression of Long Noncoding RNA NEAT1 in Adipogenesis Mol Cell Biol. 2015.10; ( PubMed, DOI )

Matsubara Y, Kato T, Kashimada K, Tanaka H, Zhi Z, Ichinose S, Mizutani S, Morio T, Chiba T, Ito Y, Saga Y, Takada S, Asahara H. TALEN-Mediated Gene Disruption on Y Chromosome Reveals Critical Role of EIF2S3Y in Mouse Spermatogenesis. Stem Cells Dev. 2015.05; 1164-1170. ( PubMed, DOI )

Otabe Koji, Nakahara Hiroyuki, Hasegawa Akihiko, Matsukawa Tetsuya, Ayabe Fumiaki, Onizuka Naoko, Inui Masafumi, Takada Shuji, Ito Yoshiaki, Sekiya Ichiro, Muneta Takeshi, Lotz Martin, Asahara Hiroshi. Transcription factor Mohawk controls tenogenic differentiation of bone marrow mesenchymal stem cells in vitro and in vivo. J Orthop Res. 2015.01; 33 (1): 1-8. ( PubMed, DOI )

Nagata Eiko, Kano Hiroki, Kato Fumiko, Yamaguchi Rie, Nakashima Shinichi, Takayama Shinichiro, Kosaki Rika, Tonoki Hidefumi, Mizuno Seiji, Watanabe Satoshi, Yoshiura Koh-Ichiro, Kosho Tomoki, Hasegawa Tomonobu, Kimizuka Mamori, Suzuki Atsushi, Shimizu Kenji, Ohashi Hirofumi, Haga Nobuhiko, Numabe Hironao, Horii Emiko, Nagai Toshiro, Yoshihashi Hiroshi, Nishimura Gen, Toda Tatsushi, Takada Shuji, Yokoyama Shigetoshi, Asahara Hiroshi, Sano Shinichiro, Fukami Maki, Ikegawa Shiro, Ogata Tsutomu. Japanese founder duplications/triplications involving BHLHA9 are associated with split-hand/foot malformation with or without long bone deficiency and Gollop-Wolfgang complex. Orphanet J Rare Dis. 2014.10; 9 (1): 125. ( PubMed, DOI )

Miyata Kohei, Yotsumoto Fusanori, Nam Sung Ouk, Odawara Takashi, Manabe Sadao, Ishikawa Toyokazu, Itamochi Hiroaki, Kigawa Junzo, Takada Shuji, Asahara Hiroshi, Kuroki Masahide, Miyamoto Shingo. Contribution of transcription factor, SP1, to the promotion of HB-EGF expression in defense mechanism against the treatment of irinotecan in ovarian clear cell carcinoma. Cancer Med. 2014.10; 3 (5): 1159-1169. ( PubMed, DOI )

Miyata Kohei, Miyata Tomoko, Nakabayashi Kazuhiko, Okamura Kohji, Naito Masashi, Kawai Tomoko, Takada Shuji, Kato Kiyoko, Miyamoto Shingo, Hata Kenichiro, Asahara Hiroshi. DNA methylation analysis of human myoblasts during in vitro myogenic differentiation: de novo methylation of promoters of muscle-related genes and its involvement in transcriptional down-regulation. Hum Mol Genet. 2014.09; 24 (2): 410-423. ( PubMed, DOI )

Takasawa Kei, Kashimada Kenichi, Pelosi Emanuele, Takagi Masatoshi, Morio Tomohiro, Asahara Hiroshi, Schlessinger David, Mizutani Shuki, Koopman Peter. FOXL2 transcriptionally represses Sf1 expression by antagonizing WT1 during ovarian development in mice. FASEB J. 2014.05; 28 (5): 2020-2028. ( PubMed, DOI )

Shinohara Masahiro, Chang Betty Y, Buggy Joseph J, Nagai Yusuke, Kodama Tatsuhiko, Asahara Hiroshi, Takayanagi Hiroshi. The orally available Btk inhibitor ibrutinib (PCI-32765) protects against osteoclast-mediated bone loss. Bone. 2014.03; 60 8-15. ( PubMed, DOI )

Onizuka Naoko, Ito Yoshiaki, Inagawa Masayo, Nakahara Hiroyuki, Takada Shuji, Lotz Martin, Toyama Yoshiaki, Asahara Hiroshi. The Mohawk homeobox transcription factor regulates the differentiation of tendons and volar plates. J Orthop Sci. 2014.01; 19 (1): 172-180. ( PubMed, DOI )

Akasaki Y, Hasegawa A, Saito M, Asahara H, Iwamoto Y, Lotz M K. Dysregulated FOXO transcription factors in articular cartilage in aging and osteoarthritis. Osteoarthritis Cartilage. 2014.01; 22 (1): 162-170. ( PubMed, DOI )

Matsubara Yohei, Chiba Tomoki, Kashimada Kenichi, Morio Tomohiro, Takada Shuji, Mizutani Shuki, Asahara Hiroshi. Transcription activator-like effector nuclease-mediated transduction of exogenous gene into IL2RG locus. Sci Rep. 2014; 4 5043. ( PubMed, DOI )

Inui Masafumi, Miyado Mami, Igarashi Maki, Tamano Moe, Kubo Atsushi, Yamashita Satoshi, Asahara Hiroshi, Fukami Maki, Takada Shuji. Rapid generation of mouse models with defined point mutations by the CRISPR/Cas9 system. Sci Rep. 2014; 4 5396. ( PubMed, DOI )

Yoshitaka Teruhito, Kawai Akira, Miyaki Shigeru, Numoto Kunihiko, Kikuta Kazutaka, Ozaki Toshifumi, Lotz Martin, Asahara Hiroshi. Analysis of microRNAs expressions in chondrosarcoma. J Orthop Res. 2013.12; 31 (12): 1992-1998. ( PubMed, DOI )

Kato Tomoko, Miyata Kohei, Sonobe Miku, Yamashita Satoshi, Tamano Moe, Miura Kento, Kanai Yoshiakira, Miyamoto Shingo, Sakuma Tetsushi, Yamamoto Takashi, Inui Masafumi, Kikusui Takefumi, Asahara Hiroshi, Takada Shuji. Production of Sry knockout mouse using TALEN via oocyte injection. Sci Rep. 2013.11; 3 3136. ( PubMed, DOI )

Shimizu Hirohito, Kubo Atsushi, Uchibe Kenta, Hashimoto Megumi, Yokoyama Shigetoshi, Takada Shuji, Mitsuoka Kazuhiko, Asahara Hiroshi. The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. PLoS One. 2013.10; 8 (10): e75754. ( PubMed, DOI )

Takada Shuji, Sato Tempei, Ito Yoshiaki, Yamashita Satoshi, Kato Tomoko, Kawasumi Miyuri, Kanai-Azuma Masami, Igarashi Arisa, Kato Tomomi, Tamano Moe, Asahara Hiroshi. Targeted gene deletion of miRNAs in mice by TALEN system. PLoS One. 2013.10; 8 (10): e76004. ( PubMed, DOI )

Gibson Gary, Asahara Hiroshi. microRNAs and cartilage. J Orthop Res. 2013.09; 31 (9): 1333-1344. ( PubMed, DOI )

Nakahara Hiroyuki, Hasegawa Akihiko, Otabe Koji, Ayabe Fumiaki, Matsukawa Tetsuya, Onizuka Naoko, Ito Yoshiaki, Ozaki Toshifumi, Lotz Martin K, Asahara Hiroshi. Transcription factor Mohawk and the pathogenesis of human anterior cruciate ligament degradation. Arthritis Rheum. 2013.08; 65 (8): 2081-2089. ( PubMed, DOI )

Rakoczy Joanna, Fernandez-Valverde Selene L, Glazov Evgeny A, Wainwright Elanor N, Sato Tempei, Takada Shuji, Combes Alexander N, Korbie Darren J, Miller David, Grimmond Sean M, Little Melissa H, Asahara Hiroshi, Mattick John S, Taft Ryan J, Wilhelm Dagmar. MicroRNAs-140-5p/140-3p modulate Leydig cell numbers in the developing mouse testis. Biol Reprod. 2013.06; 88 (6): 143. ( PubMed, DOI )

Hasegawa Akihiko, Nakahara Hiroyuki, Kinoshita Mitsuo, Asahara Hiroshi, Koziol James, Lotz Martin K. Cellular and extracellular matrix changes in anterior cruciate ligaments during human knee aging and osteoarthritis. Arthritis Res Ther. 2013.02; 15 (1): R29. ( PubMed, DOI )

Matsukawa Tetsuya, Sakai Tadahiro, Yonezawa Tomo, Hiraiwa Hideki, Hamada Takashi, Nakashima Motoshige, Ono Yohei, Ishizuka Shinya, Nakahara Hiroyuki, Lotz Martin K, Asahara Hiroshi, Ishiguro Naoki. MicroRNA-125b regulates the expression of aggrecanase-1 (ADAMTS-4) in human osteoarthritic chondrocytes. Arthritis Res Ther. 2013.02; 15 (1): R28. ( PubMed, DOI )

Takata Akemi, Otsuka Motoyuki, Yoshikawa Takeshi, Kishikawa Takahiro, Hikiba Yohko, Obi Shuntaro, Goto Tadashi, Kang Young Jun, Maeda Shin, Yoshida Haruhiko, Omata Masao, Asahara Hiroshi, Koike Kazuhiko. MicroRNA-140 acts as a liver tumor suppressor by controlling NF-kappaB activity by directly targeting DNA methyltransferase 1 (Dnmt1) expression. Hepatology. 2013.01; 57 (1): 162-170. ( PubMed, DOI )

Watanabe Takashi, Oyama Toshinao, Asada Maki, Harada Daisuke, Ito Yoshiaki, Inagawa Masayo, Suzuki Yutaka, Sugano Sumio, Katsube Ken-ichi, Karsenty Gerard, Komori Toshihisa, Kitagawa Motoo, Asahara Hiroshi. MAML1 enhances the transcriptional activity of Runx2 and plays a role in bone development. PLoS Genet. 2013.01; 9 (1): e1003132. ( PubMed, DOI )

Furumatsu Takayuki, Asahara Hiroshi. Chromatin assembly and in vitro transcription analyses for evaluation of individual protein activities in multicomponent transcriptional complexes. Methods Mol Biol. 2013; 977 193-202. ( PubMed, DOI )

Shuji Takada, Hiroshi Asahara. Current strategies for microRNA research. Mod Rheumatol. 2012.09; 22 (5): 645-653. ( PubMed, DOI )

Miyaki Shigeru, Asahara Hiroshi. Macro view of microRNA function in osteoarthritis. Nat Rev Rheumatol. 2012.09; 8 (9): 543-552. ( PubMed, DOI )

Ito Yoshiaki, Kayama Tomohiro, Asahara Hiroshi. A systems approach and skeletal myogenesis. Comp Funct Genomics. 2012.09; 2012 759407. ( PubMed, DOI )

Fukami Maki, Tsuchiya Takayoshi, Takada Shuji, Kanbara Akiko, Asahara Hiroshi, Igarashi Arisa, Kamiyama Yasunori, Nishimura Gen, Ogata Tsutomu. Complex genomic rearrangement in the SOX9 5' region in a patient with Pierre Robin sequence and hypoplastic left scapula. Am J Med Genet A. 2012.07; 158A (7): 1529-1534. ( PubMed, DOI )

Uchibe Kenta, Shimizu Hirohito, Yokoyama Shigetoshi, Kuboki Takuo, Asahara Hiroshi. Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012.07; 241 (7): 1217-1226. ( PubMed, DOI )

Yamashita Satoshi, Miyaki Shigeru, Kato Yoshio, Yokoyama Shigetoshi, Sato Tempei, Barrionuevo Francisco, Akiyama Haruhiko, Scherer Gerd, Takada Shuji, Asahara Hiroshi. L-Sox5 and Sox6 proteins enhance chondrogenic miR-140 microRNA expression by strengthening dimeric Sox9 activity. J Biol Chem. 2012.06; 287 (26): 22206-22215. ( PubMed, DOI )

Elaine F Chan, Ricky Harjanto, Hiroshi Asahara, Nozomu Inoue, Koichi Masuda, William D Bugbee, Gary S Firestein, Harish S Hosalkar, Martin K Lotz, Robert L Sah. Structural and functional maturation of distal femoral cartilage and bone during postnatal development and growth in humans and mice. Orthop. Clin. North Am.. 2012.04; 43 (2): 173-85, v. ( PubMed, DOI )

Satoshi Yamashita and Hiroshi Asahara. miRNA Functions in Arthritis Current Rheumatology Reviews. 2012; 8 98-102.

Shogo Wada, Yoshio Kato, Mitsuharu Okutsu, Shigeru Miyaki, Katsuhiko Suzuki, Zhen Yan, Stefano Schiaffino, Hiroshi Asahara, Takashi Ushida, Takayuki Akimoto. Translational suppression of atrophic regulators by microRNA-23a integrates resistance to skeletal muscle atrophy. J. Biol. Chem.. 2011.11; 286 (44): 38456-38465. ( PubMed, DOI )

Hiroshi Asahara. Switching gears to an arthritis gene expression network by SirT1 cleavage. Arthritis Rheum.. 2011.08; 63 (8): 2161-2163. ( PubMed, DOI )

Shigetoshi Yokoyama, Hiroshi Asahara. The myogenic transcriptional network. Cell. Mol. Life Sci.. 2011.06; 68 (11): 1843-1849. ( PubMed, DOI )

Motoharu Awazawa, Kohjiro Ueki, Kazunori Inabe, Toshimasa Yamauchi, Naoto Kubota, Kazuma Kaneko, Masatoshi Kobayashi, Aya Iwane, Takayoshi Sasako, Yukiko Okazaki, Mitsuru Ohsugi, Iseki Takamoto, Satoshi Yamashita, Hiroshi Asahara, Shizuo Akira, Masato Kasuga, Takashi Kadowaki. Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via a macrophage-derived IL-6-dependent pathway. Cell Metab.. 2011.04; 13 (4): 401-412. ( PubMed, DOI )

Maki Asada, Alexander Rauch, Hirohito Shimizu, Hiromi Maruyama, Shigeru Miyaki, Masafumi Shibamori, Hideki Kawasome, Hironobu Ishiyama, Jan Tuckermann, Hiroshi Asahara. DNA binding-dependent glucocorticoid receptor activity promotes adipogenesis via Krüppel-like factor 15 gene expression. Lab. Invest.. 2011.02; 91 (2): 203-215. ( PubMed, DOI )

Reiko Mizutani, Kazuaki Nakamura, Shigetoshi Yokoyama, Atsushi Sanbe, Shinji Kusakawa, Yuki Miyamoto, Tomohiro Torii, Hiroshi Asahara, Haruo Okado, Junji Yamauchi, Akito Tanoue. Developmental expression of sorting nexin 3 in the mouse central nervous system. Gene Expr. Patterns. 2011.01; 11 (1-2): 33-40. ( PubMed, DOI )

Takayuki Furumatsu, Hiroshi Asahara. Histone acetylation influences the activity of Sox9-related transcriptional complex. Acta Med. Okayama. 2010.12; 64 (6): 351-357. ( PubMed, DOI )

Ito Y, Toriuchi N, Yoshitaka T, Ueno-Kudoh H, Sato T, Yokoyama S, Nishida K, Akimoto T, Takahashi M, Miyaki S, Asahara H. The Mohawk homeobox gene is a critical regulator of tendon differentiation. Proc Natl Acad Sci USA. 2010.06; 107 (23): 10538-10542. ( PubMed, DOI )

Miyaki S, Sato T, Inoue A, Otsuki S, Ito Y, Yokoyama S, Kato Y, Takemoto F, Nakasa T, Yamashita S, Takada S, Lotz MK, Ueno-Kudo H, Asahara H. MicroRNA-140 plays dual roles in both cartilage development and homeostasis. Genes Dev. 2010.06; 24 (11): 1173-1185. ( PubMed, DOI )

Shuhei Otsuki, Sarah R Hanson, Shigeru Miyaki, Shawn P Grogan, Mitsuo Kinoshita, Hiroshi Asahara, Chi-Huey Wong, Martin K Lotz. Extracellular sulfatases support cartilage homeostasis by regulating BMP and FGF signaling pathways. Proc. Natl. Acad. Sci. U.S.A.. 2010.06; 107 (22): 10202-10207. ( PubMed, DOI )

Nakanishi K, Nakasa T, Tanaka N, Ishikawa M, Yamada K, Yamasaki K, Kamei N, Izumi B, Adachi N, Miyaki S, Asahara H, Ochi M. . Responses of microRNAs 124a and 223 following spinal cord injury in mice. Spinal Cord. 2010.03; 48 (3): 192-196. ( PubMed, DOI )

Reiji Higashiyama, Shigeru Miyaki, Satoshi Yamashita, Teruhito Yoshitaka, Görel Lindman, Yoshiaki Ito, Takahisa Sasho, Kazuhisa Takahashi, Martin Lotz, Hiroshi Asahara. Correlation between MMP-13 and HDAC7 expression in human knee osteoarthritis. Mod Rheumatol. 2010.02; 20 (1): 11-17. ( PubMed, DOI )

Shuhei Otsuki, Shawn P Grogan, Shigeru Miyaki, Mitsuo Kinoshita, Hiroshi Asahara, Martin K Lotz. Tissue neogenesis and STRO-1 expression in immature and mature articular cartilage. J. Orthop. Res.. 2010.01; 28 (1): 96-102. ( PubMed, DOI )

Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009.12; 17 (6): 836-848. ( PubMed, DOI )

Kato Y, Miyaki S, Yokoyama S, Omori S, Inoue A, Horiuchi M, Asahara H. Real-time functional imaging for monitoring miR-133 during myogenic differentiation. The international journal of biochemistry & cell biology. 2009.11; 41 (11): 2225-31. ( PubMed, DOI )

Abe Y, Oka A, Mizuguchi M, Igarashi T, Ishikawa S, Aburatani H, Yokoyama S, Asahara H, Nagao K, Yamada M, Miyashita T. EYA4, deleted in a case with middle interhemispheric variant of holoprosencephaly, interacts with SIX3 both physically and functionally. Human mutation. 2009.10; 30 (10): E946-55. ( PubMed, DOI )

Ito T, Yadav N, Lee J, Furumatsu T, Yamashita S, Yoshida K, Taniguchi N, Hashimoto M, Tsuchiya M, Ozaki T, Lotz M, Bedford MT, Asahara H. Arginine methyltransferase CARM1/PRMT4 regulates endochondral ossification. BMC developmental biology. 2009.09; 9 47. ( PubMed, DOI )

Miyaki S, Nakasa T, Otsuki S, Grogan SP, Higashiyama R, Inoue A, Kato Y, Sato T, Lotz MK, Asahara H. MicroRNA-140 is expressed in differentiated human articular chondrocytes and modulates interleukin-1 responses. Arthritis and rheumatism. 2009.09; 60 (9): 2723-30. ( PubMed, DOI )

Nagata Y, Nakasa T, Mochizuki Y, Ishikawa M, Miyaki S, Shibuya H, Yamasaki K, Adachi N, Asahara H, Ochi M. Induction of apoptosis in the synovium of mice with autoantibody-mediated arthritis by the intraarticular injection of double-stranded MicroRNA-15a. Arthritis and rheumatism. 2009.09; 60 (9): 2677-83. ( PubMed, DOI )

Yamashita S, Andoh M, Ueno-Kudoh H, Sato T, Miyaki S, Asahara H. Sox9 directly promotes Bapx1 gene expression to repress Runx2 in chondrocytes. Experimental cell research. 2009.08; 315 (13): 2231-40. ( PubMed, DOI )

Grogan SP, Miyaki S, Asahara H, D'Lima DD, Lotz MK. Mesenchymal progenitor cell markers in human articular cartilage: normal distribution and changes in osteoarthritis. Arthritis research & therapy. 2009.06; 11 (3): R85. ( PubMed, DOI )

Furumatsu T, Ozaki T, Asahara H. Smad3 activates the Sox9-dependent transcription on chromatin. The international journal of biochemistry & cell biology. 2009.05; 41 (5): 1198-204. ( PubMed, DOI )

FANTOM Consortium., Suzuki H, Forrest AR, van Nimwegen E, Daub CO, Balwierz PJ, Irvine KM, Lassmann T, Ravasi T, Hasegawa Y, de Hoon MJ, Katayama S, Schroder K, Carninci P, Tomaru Y, Kanamori-Katayama M, Kubosaki A, Akalin A, Ando Y, Arner E, Asada M, Asahara H, Bailey T, Bajic VB, Bauer D, Beckhouse AG, Bertin N, Björkegren J, Brombacher F, Bulger E, Chalk AM, Chiba J, Cloonan N, Dawe A, Dostie J, Engström PG, Essack M, Faulkner GJ, Fink JL, Fredman D, Fujimori K, Furuno M, Gojobori T, Gough J, Grimmond SM, Gustafsson M, Hashimoto M, Hashimoto T, Hatakeyama M, Heinzel S, Hide W, Hofmann O, Hörnquist M, Huminiecki L, Ikeo K, Imamoto N, Inoue S, Inoue Y, Ishihara R, Iwayanagi T, Jacobsen A, Kaur M, Kawaji H, Kerr MC, Kimura R, Kimura S, Kimura Y, Kitano H, Koga H, Kojima T, Kondo S, Konno T, Krogh A, Kruger A, Kumar A, Lenhard B, Lennartsson A, Lindow M, Lizio M, Macpherson C, Maeda N, Maher CA, Maqungo M, Mar J, Matigian NA, Matsuda H, Mattick JS, Meier S, Miyamoto S, Miyamoto-Sato E, Nakabayashi K, Nakachi Y, Nakano M, Nygaard S, Okayama T, Okazaki Y, Okuda-Yabukami H, Orlando V, Otomo J, Pachkov M, Petrovsky N, Plessy C, Quackenbush J, Radovanovic A, Rehli M, Saito R, Sandelin A, Schmeier S, Schönbach C, Schwartz AS, Semple CA, Sera M, Severin J, Shirahige K, Simons C, St Laurent G, Suzuki M, Suzuki T, Sweet MJ, Taft RJ, Takeda S, Takenaka Y, Tan K, Taylor MS, Teasdale RD, Tegnér J, Teichmann S, Valen E, Wahlestedt C, Waki K, Waterhouse A, Wells CA, Winther O, Wu L, Yamaguchi K, Yanagawa H, Yasuda J, Zavolan M, Hume DA, Riken Omics Science Center., Arakawa T, Fukuda S, Imamura K, Kai C, Kaiho A, Kawashima T, Kawazu C, Kitazume Y, Kojima M, Miura H, Murakami K, Murata M, Ninomiya N, Nishiyori H, Noma S, Ogawa C, Sano T, Simon C, Tagami M, Takahashi Y, Kawai J, Hayashizaki Y. The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line. Nature genetics. 2009.05; 41 (5): 553-62. ( PubMed, DOI )

Yamasaki K, Nakasa T, Miyaki S, Ishikawa M, Deie M, Adachi N, Yasunaga Y, Asahara H, Ochi M. Expression of MicroRNA-146a in osteoarthritis cartilage. Arthritis and rheumatism. 2009.04; 60 (4): 1035-41. ( PubMed, DOI )

Hikata T, Takaishi H, Takito J, Hakozaki A, Furukawa M, Uchikawa S, Kimura T, Okada Y, Matsumoto M, Yoshimura A, Nishimura R, Reddy SV, Asahara H, Toyama Y. PIAS3 negatively regulates RANKL-mediated osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblasts. Blood. 2009.03; 113 (10): 2202-12. ( PubMed, DOI )

Kumagishi K, Nishida K, Yamaai T, Momota R, Miyaki S, Hirohata S, Naito I, Asahara H, Ninomiya Y, Ohtsuka A. A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAMTS9) expression by chondrocytes during endochondral ossification. Archives of histology and cytology. 2009; 72 (3): 175-85. ( PubMed )

Shimizu H, Uchibe K, Asahara H. Large-scale whole mount in situ hybridization of mouse embryos. Methods in molecular biology (Clifton, N.J.). 2009; 577 167-79. ( PubMed, DOI )

Sakai N, Terami H, Suzuki S, Haga M, Nomoto K, Tsuchida N, Morohashi K, Saito N, Asada M, Hashimoto M, Harada D, Asahara H, Ishikawa T, Shimada F, Sakurada K. Identification of NR5A1 (SF-1/AD4BP) gene expression modulators by large-scale gain and loss of function studies. The Journal of endocrinology. 2008.09; 198 (3): 489-97. ( PubMed, DOI )

Nakasa T, Miyaki S, Okubo A, Hashimoto M, Nishida K, Ochi M, Asahara H. Expression of microRNA-146 in rheumatoid arthritis synovial tissue. Arthritis and rheumatism. 2008.05; 58 (5): 1284-92. ( PubMed, DOI )

Hashimoto M, Nakasa T, Hikata T, Asahara H. Molecular network of cartilage homeostasis and osteoarthritis. Medicinal research reviews. 2008.05; 28 (3): 464-81. ( PubMed, DOI )

Yokoyama S, Hashimoto M, Shimizu H, Ueno-Kudoh H, Uchibe K, Kimura I, Asahara H. Dynamic gene expression of Lin-28 during embryonic development in mouse and chicken. Gene expression patterns : GEP. 2008.02; 8 (3): 155-60. ( PubMed, DOI )

Teruhito Yoshitaka, Hiroshi Asahara,. Epigenetics and Cartilage Regulation US Musculoskeletal Review. 2008; 3 (1): 45-47.

Shimizu H, Yokoyama S, Asahara H. Growth and differentiation of the developing limb bud from the perspective of chondrogenesis. Development, growth & differentiation. 2007.08; 49 (6): 449-54. ( PubMed, DOI )

Taniguchi N, Yoshida K, Ito T, Tsuda M, Mishima Y, Furumatsu T, Ronfani L, Abeyama K, Kawahara K, Komiya S, Maruyama I, Lotz M, Bianchi ME, Asahara H. Stage-specific secretion of HMGB1 in cartilage regulates endochondral ossification. Molecular and cellular biology. 2007.08; 27 (16): 5650-63. ( PubMed, DOI )

Sato K, Suematsu A, Nakashima T, Takemoto-Kimura S, Aoki K, Morishita Y, Asahara H, Ohya K, Yamaguchi A, Takai T, Kodama T, Chatila TA, Bito H, Takayanagi H. Regulation of osteoclast differentiation and function by the CaMK-CREB pathway. Nature medicine. 2006.12; 12 (12): 1410-6. ( PubMed, DOI )

Furumatsu T, Tsuda M, Yoshida K, Taniguchi N, Ito T, Hashimoto M, Ito T, Asahara H. Sox9 and p300 cooperatively regulate chromatin-mediated transcription. The Journal of biological chemistry. 2005.10; 280 (42): 35203-8. ( PubMed, DOI )

Furumatsu T, Tsuda M, Taniguchi N, Tajima Y, Asahara H. Smad3 induces chondrogenesis through the activation of SOX9 via CREB-binding protein/p300 recruitment. The Journal of biological chemistry. 2005.03; 280 (9): 8343-50. ( PubMed, DOI )

Kawakami Y, Tsuda M, Takahashi S, Taniguchi N, Esteban CR, Zemmyo M, Furumatsu T, Lotz M, Izpisúa Belmonte JC, Asahara H. Transcriptional coactivator PGC-1alpha regulates chondrogenesis via association with Sox9. Proceedings of the National Academy of Sciences of the United States of America. 2005.02; 102 (7): 2414-9. ( PubMed, DOI )

Omoto S, Nishida K, Yamaai Y, Shibahara M, Nishida T, Doi T, Asahara H, Nakanishi T, Inoue H, Takigawa M. Expression and localization of connective tissue growth factor (CTGF/Hcs24/CCN2) in osteoarthritic cartilage. Osteoarthritis and cartilage. 2004.10; 12 (10): 771-8. ( PubMed, DOI )

Kato T, Asahara H, Kurokawa MS, Fujisawa K, Hasunuma T, Inoue H, Tsuda M, Takahashi S, Motokawa S, Sumida T, Nishioka K. HTLV-I env protein acts as a major antigen in patients with HTLV-I-associated arthropathy. Clinical rheumatology. 2004.10; 23 (5): 400-9. ( PubMed, DOI )

Nishida K, Komiyama T, Miyazawa S, Shen ZN, Furumatsu T, Doi H, Yoshida A, Yamana J, Yamamura M, Ninomiya Y, Inoue H, Asahara H. Histone deacetylase inhibitor suppression of autoantibody-mediated arthritis in mice via regulation of p16INK4a and p21(WAF1/Cip1) expression. Arthritis and rheumatism. 2004.10; 50 (10): 3365-76. ( PubMed, DOI )

Kawakami Y, Rodríguez-León J, Koth CM, Büscher D, Itoh T, Raya A, Ng JK, Esteban CR, Takahashi S, Henrique D, Schwarz MF, Asahara H, Izpisúa Belmonte JC. MKP3 mediates the cellular response to FGF8 signalling in the vertebrate limb. Nature cell biology. 2003.06; 5 (6): 513-9. ( PubMed, DOI )

Canettieri G, Morantte I, Guzmán E, Asahara H, Herzig S, Anderson SD, Yates JR 3rd, Montminy M. Attenuation of a phosphorylation-dependent activator by an HDAC-PP1 complex. Nature structural biology. 2003.03; 10 (3): 175-81. ( PubMed, DOI )

Asahara H, Tartare-Deckert S, Nakagawa T, Ikehara T, Hirose F, Hunter T, Ito T, Montminy M. Dual roles of p300 in chromatin assembly and transcriptional activation in cooperation with nucleosome assembly protein 1 in vitro. Molecular and cellular biology. 2002.05; 22 (9): 2974-83. ( PubMed )

W Xu, H Chen, K Du, H Asahara, M Tini, B M Emerson, M Montminy, R M Evans. A transcriptional switch mediated by cofactor methylation. Science. 2001.12; 294 (5551): 2507-2511. ( PubMed, DOI )

H Asahara, B Santoso, E Guzman, K Du, P A Cole, I Davidson, M Montminy. Chromatin-dependent cooperativity between constitutive and inducible activation domains in CREB. Mol. Cell. Biol.. 2001.12; 21 (23): 7892-7900. ( PubMed, DOI )

F Long, E Schipani, H Asahara, H Kronenberg, M Montminy. The CREB family of activators is required for endochondral bone development. Development. 2001.02; 128 (4): 541-550. ( PubMed )

T Sekine, K Masuko-Hongo, T Matsui, H Asahara, M Takigawa, K Nishioka, T Kato. Recognition of YKL-39, a human cartilage related protein, as a target antigen in patients with rheumatoid arthritis. Ann. Rheum. Dis.. 2001.01; 60 (1): 49-54. ( PubMed )

K Asaumi, T Nakanishi, H Asahara, H Inoue, M Takigawa. Expression of neurotrophins and their receptors (TRK) during fracture healing. Bone. 2000.06; 26 (6): 625-633. ( PubMed )

K Du, H Asahara, U S Jhala, B L Wagner, M Montminy. Characterization of a CREB gain-of-function mutant with constitutive transcriptional activity in vivo. Mol. Cell. Biol.. 2000.06; 20 (12): 4320-4327. ( PubMed )

M Shibahara, K Nishida, H Asahara, T Yoshikawa, S Mitani, Y Kondo, H Inoue. Increased osteocyte apoptosis during the development of femoral head osteonecrosis in spontaneously hypertensive rats. Acta Med. Okayama. 2000.04; 54 (2): 67-74. ( PubMed, DOI )

L F Michael, H Asahara, A I Shulman, W L Kraus, M Montminy. The phosphorylation status of a cyclic AMP-responsive activator is modulated via a chromatin-dependent mechanism. Mol. Cell. Biol.. 2000.03; 20 (5): 1596-1603. ( PubMed )

H Asahara, S Dutta, H Y Kao, R M Evans, M Montminy. Pbx-Hox heterodimers recruit coactivator-corepressor complexes in an isoform-specific manner. Mol. Cell. Biol.. 1999.12; 19 (12): 8219-8225. ( PubMed )

M Suzuki, H Asahara, S Endo, K Inada, M Doi, K Kuroda, A Ogawa. Increased levels of nitrite/nitrate in the cerebrospinal fluid of patients with subarachnoid hemorrhage. Neurosurg Rev. 1999.10; 22 (2-3): 96-98. ( PubMed )

T Maeda, H Keino, H Asahara, M Taniguchi, K Nishioka, T Sumida. Decreased TCR AV24AJ18+ double-negative T cells in rheumatoid synovium. Rheumatology (Oxford). 1999.02; 38 (2): 186-188. ( PubMed )

K Okamoto, H Asahara, T Kobayashi, H Matsuno, T Hasunuma, T Kobata, T Sumida, K Nishioka. Induction of apoptosis in the rheumatoid synovium by Fas ligand gene transfer. Gene Ther.. 1998.03; 5 (3): 331-338. ( PubMed, DOI )

T Sumida, T Hasunuma, H Asahara, T Maeda, K Nishioka. Rheumatoid arthritis and apoptosis. Intern. Med.. 1998.02; 37 (2): 184-188. ( PubMed )

H Takagoshi, H Hashizume, K Nishida, S Masaoka, H Asahara, H Inoue. Fibrous structure and connection surrounding the metacarpophalangeal joint. Acta Med. Okayama. 1998.02; 52 (1): 19-26. ( PubMed, DOI )

J Pu, K Nishida, H Inoue, H Asahara, A Ohtsuka, T Murakami. Mast cells in osteoarthritic and rheumatoid arthritic synovial tissues of the human knee. Acta Med. Okayama. 1998.02; 52 (1): 35-39. ( PubMed, DOI )

K Fujisawa, K Okamoto, H Asahara, T Hasunuma, T Kobata, T Kato, T Sumida, K Nishioka. Evidence for autoantigens of Env/Tax proteins in human T cell leukemia virus type I Env-pX transgenic mice. Arthritis Rheum.. 1998.01; 41 (1): 101-109. ( PubMed, DOI )

T Kobata, K Takasaki, H Asahara, N M Hong, K Masuko-Hongo, T Kato, S Hirose, T Shirai, N Kayagaki, H Yagita, K Okumura, K Nishioka. Apoptosis with FasL+ cell infiltration in the periphery and thymus of corrected autoimmune mice. Immunology. 1997.10; 92 (2): 206-213. ( PubMed )

C Xue, T Hasunuma, H Asahara, W Yin, T Maeda, K Fujisawa, Y Dong, T Sumida, K Nishioka. Transcriptional regulation of the HOX4C gene by basic fibroblast growth factor on rheumatoid synovial fibroblasts. Arthritis Rheum.. 1997.09; 40 (9): 1628-1635. ( PubMed, DOI )

H Asahara, K Fujisawa, T Kobata, T Hasunuma, T Maeda, M Asanuma, N Ogawa, H Inoue, T Sumida, K Nishioka. Direct evidence of high DNA binding activity of transcription factor AP-1 in rheumatoid arthritis synovium. Arthritis Rheum.. 1997.05; 40 (5): 912-918. ( PubMed, DOI )

M Suzuki, A Ogawa, H Asahara, S Endo, K Inada. Nitric oxide and vasospasm. J. Neurosurg.. 1997.04; 86 (4): 741-742. ( PubMed )

H Asahara, T Hasunuma, T Kobata, H Inoue, U Muller-Ladner, S Gay, T Sumida, K Nishioka. In situ expression of protooncogenes and Fas/Fas ligand in rheumatoid arthritis synovium. J. Rheumatol.. 1997.03; 24 (3): 430-435. ( PubMed )

T Sumida, T T Hoa, H Asahara, T Hasunuma, K Nishioka. T cell receptor of Fas-sensitive T cells in rheumatoid synovium. J. Immunol.. 1997.02; 158 (4): 1965-1970. ( PubMed )

T Hasunuma, N Kayagaki, H Asahara, S Motokawa, T Kobata, H Yagita, H Aono, T Sumida, K Okumura, K Nishioka. Accumulation of soluble Fas in inflamed joints of patients with rheumatoid arthritis. Arthritis Rheum.. 1997.01; 40 (1): 80-86. ( PubMed )

Yokoi I, Kabuto H, Habu H, Inada K, Toma J, Asahara H, Mori A.. Structure-activity relationships of guanidine compounds on brain nitric oxide synthase activity. Guanidino Compounds: 2,. 1997; 3-7.

Habu H, Yokoi I, Kabuto H, Asahara H, Toma J, Inada K, Mori A.. The role of nitric oxide on α-guanidinoglutaric acid induced epileptic discharges. Guanidino Compounds: 2,. 1997; 373-377.

H Asahara, T Hasumuna, T Kobata, H Yagita, K Okumura, H Inoue, S Gay, T Sumida, K Nishioka. Expression of Fas antigen and Fas ligand in the rheumatoid synovial tissue. Clin. Immunol. Immunopathol.. 1996.10; 81 (1): 27-34. ( PubMed )

T Hasunuma, T T Hoa, H Aono, H Asahara, S Yonehara, K Yamamoto, T Sumida, S Gay, K Nishioka. Induction of Fas-dependent apoptosis in synovial infiltrating cells in rheumatoid arthritis. Int. Immunol.. 1996.10; 8 (10): 1595-1602. ( PubMed )

K Fujisawa, H Asahara, K Okamoto, H Aono, T Hasunuma, T Kobata, Y Iwakura, S Yonehara, T Sumida, K Nishioka. Therapeutic effect of the anti-Fas antibody on arthritis in HTLV-1 tax transgenic mice. J. Clin. Invest.. 1996.07; 98 (2): 271-278. ( PubMed, DOI )

H Hashizume, H Asahara, K Nishida, H Inoue, T Konishiike. Histopathology of Kienböck's disease. Correlation with magnetic resonance and other imaging techniques. J Hand Surg Br. 1996.02; 21 (1): 89-93. ( PubMed )

H Asahara, A Kawai, Y Harada, M Senda, H Inoue. Spinal schwannomas: a review of 42 cases. Acta Med. Okayama. 1996.02; 50 (1): 25-28. ( PubMed, DOI )

H Asahara, I Yokoi, T Tamada, H Kabuto, N Ogawab, A Mori, H Inoue. Increased cerebrospinal fluid nitrite and nitrate levels in patients with lumbar spondylosis. Res. Commun. Mol. Pathol. Pharmacol.. 1996.01; 91 (1): 77-83. ( PubMed )

H Asahara, M Asanuma, N Ogawa, S Nishibayashi, H Inoue. High DNA-binding activity of transcription factor NF-kappa B in synovial membranes of patients with rheumatoid arthritis. Biochem. Mol. Biol. Int.. 1995.11; 37 (5): 827-832. ( PubMed )

H Asahara, H Kabuto, I Yokoi, H Habu, A Mori, H Inoue. Nitric oxide synthase inhibited by audouine in the rat brain. Neuroreport. 1995.05; 6 (8): 1146-1148. ( PubMed )

H Kabuto, I Yokoi, H Habu, H Asahara, A Mori. Inhibitory effect of arcaine on nitric oxide synthase in the rat brain. Neuroreport. 1995.02; 6 (3): 554-556. ( PubMed )

Suzuki H, Asahara H. [Analysis of Musculoskeletal Systems and Their Diseases. The research for musculoskeletal disease using genome editing technology] Clin Calcium. 2015.08; 1169-1174. ( PubMed, DOI )

Asahara Hiroshi. [miRNAs in cartilage development]. Clin Calcium. 2012.05; 22 (5): 653-657. ( PubMed, DOI )

Tanaka-Watanabe Yoko, Asahara Hiroshi. [Joint and microRNA]. Nihon Rinsho Meneki Gakkai Kaishi. 2012; 35 (6): 447-454. ( PubMed )

中道亮、淺原弘嗣. 実験医学. 羊土社, 2022.11 機械感受性イオンチャネルPIEZO1は腱を介して身体能力を制御する (ISBN : 978-4-7581-2561-1)

中道亮、淺原弘嗣. 化学 2022年8月号. 化学同人, 2022.07 化学掲示板　新聞に載った注目記事（6月）

中道亮、千葉朋希、伊藤義晃、浅原弘嗣. 疾患バイオマーカーとしてのマイクロRNAと診断応用. シーエムシー出版, 2022.06 第26章　miRNA機能解析技術の進歩 (ISBN : 978-4-7813-1667-3)

堤　大樹，中道　亮，浅原弘嗣. 実験医学. 羊土社, 2020.09 腱のバイオロジーと筋-腱連関 (ISBN : 978-4-7581-2536-9)

片岡健輔，中道　亮，淺原弘嗣. 実験医学増刊. 羊土社, 2020.04 メカニカルストレスに依存した腱・靱帯組織の恒常性維持機構 (ISBN : 978-4-7581-0386-2)

中道亮、片岡健輔、淺原弘嗣. 整形・災害外科. 金原出版(株), 2020.03 腱・靱帯組織の恒常性維持と再生を制御する分子メカニズム

片岡健輔、淺原弘嗣. 腱/靱帯におけるメカノバイオロジー. ニューサイエンス社, 2019.11

宮田康平、淺原弘嗣. THE BONE. メディカルレビュー社, 2019.05 特集　運動器を構成する骨・軟骨・関節・筋肉・靭帯・腱のトピックー骨格筋分化の分子制御機構ー

松島 隆英, 淺原 弘嗣. ゲノム編集のヒトへの応用の展望と問題点. (有)科学評論社, 2019.02 リウマチ科

千葉 朋希, 淺原 弘嗣. 遺伝子医学. (株)メディカルドゥ, 2019.01 【ゲノム編集と倫理】 ゲノム編集における技術革新

中筋 貴史, 淺原 弘嗣, 木寺 信之, 岩原 由樹, 石川 智則, 宮坂 尚幸. 日本生殖医学会雑誌. (一社)日本生殖医学会, 2017.10 Y染色体遺伝子Zfy1,2の精子形成に対する制御機構の解明

片岡 健輔, 淺原 弘嗣. 整形・災害外科. 金原出版(株), 2017.07 新しい医療技術　メカノバイオロジーの進歩

鈴木英嗣, 伊藤義晃, 浅原弘嗣. 実験医学. 羊土社, 2016.12 Mohawkノックアウトラットでは腱分化機構が破綻し、アキレス腱での異所性骨化を呈する

篠原正浩、浅原弘嗣. 骨組織系の表現系解析. 羊土社, 2016

山下 聡, 浅原 弘嗣. 腎と骨代謝. 日本メディカルセンター, 2014.07 【骨カルシウム代謝調節最前線】 軟骨細胞分化とmiRNA

久保 純, 浅原 弘嗣. 生体の科学. 医学書院, 2014.06 仮説と戦略 胚発生期における遺伝子制御ネットワーク

佐藤 天平, 浅原 弘嗣. Medical Science Digest. ニュー・サイエンス社, 2014.06 【RNA疾患-最新の病態解析から治療法展望まで-】 ノンコーディングRNAによるHox遺伝子制御機構

田中 陽子, 浅原 弘嗣. 日本臨床. 日本臨床社, 2014.04 【最新関節リウマチ学-寛解・治癒を目指した研究と最新治療-】 関節リウマチの発症要因と発症メカニズム　発症メカニズム　microRNA

望月 祐輔, 篠原 正浩, 浅原 弘嗣. 日本臨床. 日本臨床社, 2014.04 【最新関節リウマチ学-寛解・治癒を目指した研究と最新治療-】 関節リウマチの病理・病態　骨軟骨の病態形成　関節リウマチにおける関節軟骨破壊と保護の分子メカニズム

小田邉 浩二, 浅原 弘嗣, Lotz Martin. Bone Joint Nerve. アークメディア, 2014.01 【中高年齢者の半月板変性】 (Part1)基礎　変性半月板の病理

中道 亮, 浅原 弘嗣. 整形・災害外科. 金原出版(株), 2013.04 【再生医療の現況と最前線】 未来の再生医療に向けて　靱帯・腱の発生機構の発見と臨床応用への展望

内藤 昌志, 浅原 弘嗣. 腎と骨代謝. 日本メディカルセンター, 2013.04 【サルコペニアと骨代謝】 筋細胞分化の分子メカニズム

浅原 弘嗣. 最新医学. 最新医学社, 2013.03 【自己免疫疾患・アレルギー疾患(前篇)　免疫の基礎、検査、治療】 新しい研究手法・検査　関節炎とマイクロRNA

荒巻 敏寛, 浅原 弘嗣. Bone Joint Nerve. アークメディア, 2013.01 【サルコペニア-筋研究の最前線-】 (Part1)基礎　骨格筋分化の分子メカニズム

伊藤 義晃, 浅原 弘嗣. 炎症と免疫. 先端医学社, 2012.12 【microRNA研究のトピックス】 関節リウマチとmicroRNA

田中 陽子, 浅原 弘嗣. 日本臨床免疫学会会誌. 日本臨床免疫学会, 2012.12 関節とmicroRNA

松島 隆英, 浅原 弘嗣. 炎症と免疫. 先端医学社, 2012.10 【炎症が慢性化する機構とその制御】 慢性炎症とマイクロRNA

中原 啓行, 浅原 弘嗣. 遺伝子医学MOOK. メディカル ドゥ, 2012.09 【臨床・創薬利用が見えてきたmicroRNA】 (第1章)microRNA診断　整形外科疾患におけるmicroRNA

浅原 弘嗣. 整形外科. 南江堂, 2012.08 システムアプローチによる運動器の発生と再生メカニズムの解明

鬼塚 奈緒子, 浅原 弘嗣. 臨床整形外科. 医学書院, 2012.07 最新基礎科学　知っておきたい ホメオボックス遺伝子Mohawkと腱の発生

千葉 朋希, 浅原 弘嗣. リウマチ科. 科学評論社, 2012.07 RAの病態形成におけるmicroRNAの役割

浅原 弘嗣. 最新医学. 最新医学社, 2012.05 関節炎におけるマイクロRNAの機能

浅原 弘嗣. Clinical Calcium. 医薬ジャーナル社, 2012.04 【骨代謝研究におけるエピゲノムの最先端】 軟骨細胞分化におけるmiRNA

Hiroshi Asahara. Tendon regeneration and functional enhancement for physical performance via Piezo1-Mkx axis. International Symposium on Mechanobiology for Human Health：8 years 2023.03.22

Hiroshi Asahara. Athlete Giftedness and Tendon. Molecular Medicine Department Retreat 2022.10.10 スクリプス研究所

Hiroshi Asahara. Muscle to tendon for physical performance. the 9th Seoul Symposium on Bone Health & the 33rd Spring Scientific Congress of the Korean Society for Bone and Mineral Research (SSBH 2021) 2021.06.04

Hiroshi Asahara. Tenocytes: gatekeepers of tendon homeostasis. EULAR 2021 2021.06.03

Hiroshi Asahara. Mechano-signal on tendon and ligament homeostasis via Mkx. International Symposium on AMED “Mechanobiology” Project 2020.02.08

Hiroshi Asahara. Mechano-signal Pathway Regulating Tendon and Ligament Via Mkx. AMED革新的先端研究開発支援事業（AMED-CREST,PRIME）「メカノバイオ」領域　令和元年度　領域会議 2020.02.06

Hiroshi Asahara. Homeostasis of tendons and ligaments connecting musculoskeletal system. Japan Bone Academy2019 2019.12.15

Hiroshi Asahara. Characterization of a novel Sox9 enhancer and down-stream targets with implications in Arthritis parthenogenesis and therapeutics.. SOX meeting2019 2019.10.01

淺原弘嗣. Lecture I“Cartilage homeostasis and arthritis pathogenesis via RNA regulation”. 16th Meeting of Bone Biology Forum 2019.08.16

浅原弘嗣 、茂久田翔、伊藤義晃、中道亮、杉山英二 、松崎時夫. Wwp2 maintains cartilage homeostasis through regulation of Adamts5. 第5回日本骨免疫学会 2019.06.26

Hiroshi Asahara, Sho Mokuda, Yoshiaki Ito, Masafumi Inui, Ryo Nakamichi, Tomoki Chiba, Ryota Kurimoto, Takahide Matsushima. miRNAs in arthritis pathogenesis and therapy. The 24th Annual Meeting of the RNA Society 2019.06.14

Hiroshi Asahara. miRNAs in arthritis pathogenesis and therapy. 2019 Keystone Symposia Conference 2019.04.17

淺原弘嗣. 腱・靭帯のメカノプロパティを応用した再生医療. FAOPS2019 2019.03.31

Hiroshi Asahara. Genome dynamics for chondrogenesis and miRNAs for cartilage homeostasis via Sox9. Cartilage GRC 2019 2019.03.21

Hiroshi Asahara. miRNAs in arthritis pathogenesis and therapy. The 20th Takeda Science Foundation Symposium on BioSciences 2019.02.01

Hiroshi Asahara. Mechano-signal pathway regulating tendon and ligament via Mkx. ORS Tendon Section 2018 Conference 2018.11.16

Hiroshi Asahara. miRNAs in arthritis pathogenesis and therapy. JAJ　RNA　2018 2018.11.05

Hiroshi Asahara. Transcriptional and translational regulation of musculoskeletal development and arthritis pathogenesis.. Marc Montminy's 62nd Birthday Symposium 2018.08.31

Hiroshi Asahara. The completely automated ChIP system performed by LabDroid ”Maholo”. Robotics and Semantic Systems for Biology (RSSB) 2 2018.01.27

Hiroshi Asahara. Transcription Factor Mkx Regulates Tendon Development, Homeostasis and Regeneration. Collagen Gordon Research Conference 2017.07.16 New London

Hiroshi Asahara. miRNA in Cancer, Arthritis and Homeostasis. The 43rd Naito Conference 2017.06.29

Hiroshi Asahara. Identification of targets of tumor suppressor microRNA-34a using a reporter library system . RNA　2017－Prague 2017.05.25 Prague

Hiroshi Asahara. Tendon development and regeneration analyzed by Mkx KO Rat. The 291st IMEG Seminar 2017.02.24

Hiroshi Asahara、Yoshiaki Ito. The role of microRNA-455 in cartilage. 第19回武田科学振興財団生命科学シンポジウム 2017.01.10

Hiroshi Asahara. Gene targeting of the transcription factor Mohawk in rats causes heterotopic ossification of Achilles tendon via failed tenogenesis. Stem Cell, Growth Factor Signaling and Bone Biology 2016.07.25 Hangzhou

Hiroshi Asahara,Tomoki Chiba,Kentaro Abe,Yoshiaki Ito. Inflammatory signal regulation at RNA level. Biochemistry and Molecular Biology 2015.12.01 Hyogo

浅原弘嗣. Skeletal development regulated at the level of RNA. 第12回Bone Biology Forum 2015.08.22 千葉

Hiroshi Asahara. Regulation of Hox-code at RNA level during skeletal development.. The ICMRS Conference and Xiangya Osteoporsis Forum 2015.04.10 China

Hiroshi Asahara. The Role of Mkx in Tendon and Spinal Disc Homeostasis and Regeneration. The ICMRS Conference and Xiangya Osteoporsis Forum 2015.04.06 China

Asahara H,Tempei Sato, Masafumi Inui. The Critical role of miRNAs at the edge of Hox-code during skeletal development. Gordon Research Conference 2015.03.23 Houston

Hiroshi Asahara. Genome editing technology for arthritis pathophysiology. INTERNATIONAL FORUM OF THE UNIVERSITY SCIENCE-2014 In conjunction with THE 2nd BIO RHEUMATOLOGY INTERNATIONAL CONGRESS(BRIC2014) THE 9th GLOBAL ARTHRITIS RESEARCH NETWORK(GRAN) 2014 MEETING MOSCOW 2014.06.06 Moscow

淺原弘嗣. ヒト型ロボティックス　マホロを活用した、タンパクとDNAおよびRNAの相互作用の解析. ソニークリニカルサミット研究会 2024.03.08

淺原弘嗣. 「関節」機能を賦活化する腱組織の分子・生理・ゲノム研究. 第36回日本軟骨代謝学会 2024.02.16

淺原弘嗣. 腱に紡がれる筋骨格系の恒常性と運動機能維持機構. 第59回インスリン研究会 2024.02.03

淺原弘嗣. Athlete Giftedness と遺伝子. 第8回日本骨免疫学会冬期学術集会 2024.01.31

淺原弘嗣. 腱に紡がれる運動機能とその破綻による関節疾患の治療と予防. 第20回ファンクショナルフード学術集会 2024.01.19

淺原弘嗣. Athlete Giftednessと遺伝子. 第3回COMITセミナー 2023.12.08

淺原弘嗣. Athelete Giftednessと遺伝子. 第73回兵庫県糖尿病懇話会 2023.11.11

淺原弘嗣. セッションテーマ：3S07a「臓器リモデリング・可塑性とその破綻」. 第96回日本生化学会大会 2023.11.02

淺原弘嗣. Athletic ability regulated by Genetics. 第22回「認識と形成」研究会 2023.10.21

淺原弘嗣. 腱に紡がれる運動機能とその破綻による関節疾患. 第43回日本関節運動学的アプローチ医学会（AKA）　学術集会 2023.09.18

淺原弘嗣. Athlete Giftednessと遺伝子. 第1回 東京科学大学（仮称）交流オンラインセミナー 2023.09.11

淺原弘嗣. Athletic giftednessと遺伝子. 第22回ロコモティブ—メタボリック症候群研究会 2023.09.07

淺原弘嗣. Athlete Giftednessと遺伝子. 第2回スポーツ遺伝学研究会 2023.08.21

淺原弘嗣. 手外科と運動能力を左右する腱の遺 伝子. 第18回上肢外科サマーセミナー in Kasaoka 2023.07.29

淺原弘嗣. RNA階層における軟骨組織発生と恒常性制御機構と治療への応用. 第41回日本骨代謝学会学術集会 2023.07.28

淺原弘嗣. 腱に紡がれる運動機能とその破綻による関節疾患. 第41回日本骨代謝学会学術集会 2023.07.27

淺原弘嗣. Piezo1-Mkx axisで紡がれる腱を起点とした運動機能の向上と再生. 第44回日本炎症・再生医学会 2023.07.12

淺原弘嗣. 腱と遺伝子と運動機能. 第52回 御茶ノ水整形外科卒後研修セミナー 2023.07.09

淺原弘嗣. 腱に紡がれる運動機能とメカノ遺伝子ネットワーク. 第62回日本生体医工学会大会 2023.05.19

淺原弘嗣. 腱の紡ぐ運動機能とその破綻による整形外科疾患. 第96回日本整形外科学会 2023.05.11

淺原弘嗣. 組織・時期特異的な複数遺伝子編集マウス作製技術開発. 「認識と形成」分科会 2023.02.24

淺原弘嗣. 腱と運動機能. 第７回日本骨免疫学会ウィンタースクール 2023.02.01

淺原弘嗣. スポーツの才能と遺伝子. 学習院大学・ブランディングシンポジウム 2022.12.17

淺原弘嗣. アスリートのGIFTEDNESSから見た運動機能解析. 第37回日本整形外科学会基礎学術集会 2022.10.14

淺原弘嗣. 腱と歯根膜におけるメカノ刺激. 第64回歯科基礎医学会学術大会 2022.09.17

淺原弘嗣. 破天荒な研究者、永遠に. 第21回運動器科学研究会 2022.09.16

淺原弘嗣. ゲノム編集で初めて明らかにされるゲノム情報. 広島大学先端科学セミナー「“ゲノム編集”で未来社会を拓く」 2022.09.14

淺原弘嗣. アスリートの能力とGIFTEDNESS. TIP BB（ブルーバード）セミナー 2022.08.03

淺原弘嗣. アスリートのGIFTEDNESSから見た運動機能解析. 第43回日本炎症・再生医学会 2022.07.07

淺原弘嗣. アスリートのGIFTEDNESSから見た結合組織の活性. 第54回日本結合組織学会学術大会 2022.06.25

淺原弘嗣. スポーツの才能と遺伝子. 信州骨代謝多職種セミナー 2022.05.27

淺原弘嗣. スポーツの才能と遺伝子. 松本歯科大学ランチタイムセミナー 2022.05.27

淺原弘嗣. メカノ刺激と運動能力の制御. 第95回日本整形外科学会学術総会 2022.05.20

淺原弘嗣. 整形外科学・発生生物学からみたリウマチ学の用と美. 2022年度日本リウマチ学会　学会賞授賞式 2022.04.25

淺原弘嗣. RNA階層における軟骨組織発生と恒常性制御機構と治療への応用. 第21回日本再生医療学会総会 2022.03.18

淺原弘嗣. メカノ刺激と運動能力の制御. 第21回日本再生医療学会総会 2022.03.18

淺原弘嗣. 腱・靱帯をモデルとした細胞内・外メカノ・シグナルの解明と その応用によるバイオ靱帯の創出. AMEDメカノバイオロジー令和3年度 領域会議 2022.01.19

淺原弘嗣. Athlete Giftednessの正体は!?. 「認識と形成」2022　冬の討論会 2022.01.07

淺原弘嗣. 骨格筋における遺伝子発現制御機構の最前線. 第7回日本筋学会学術集会 2021.12.11

淺原弘嗣. 腱の研究であなたの健康を堅持する. 2021年度東京医科歯科大学公開講座 2021.12.08

淺原弘嗣、中道亮、堤大樹、栗本遼太. 脊椎椎間板におけるMkxの機能解析. 日本脊椎関節炎学会第31回学術集会 2021.09.11

淺原弘嗣. Athlete Giftednessの正体は!?. 「認識と形成」研究会 2021.08.28

淺原弘嗣. RNAレギュローム解析による組織恒常性維持機構の解明との治療分子標的の探索. 創生医学コンソーシアム第一回研究発表会 2021.08.27

淺原弘嗣. 生命のレゾンデートルと向き合う天空のキャンパス. 2021年度TMDU医学科サマープログラム(SP) 2021.08.11

淺原弘嗣. 腱・靱帯の恒常性維持と再生メカニズム. 第20回日本再生医療学会総会 2021.03.11

淺原弘嗣. 筋・腱・靭帯の形態形成と恒常性維持機構の解明. 第35回日本整形外科学会基礎学術集会 2020.10.16 web

淺原弘嗣. グラント獲得・論文受理の可能性を僅かにでもあげるためには. 第35回日本整形外科学会基礎学術集会 2020.10.15

淺原弘嗣、松島隆英. タンパク質の網羅的細胞内ダイナミクス解析. 第93回日本生化学会大会 2020.09.15 web

淺原弘嗣. RNA結合タンパクのシステマティックな機能解析. 第42回日本分子生物学会年会 2019.12.05

淺原弘嗣. リウマチ・関節炎を制御するmiRNA. 第6回ベーシックリサーチカンファレンス 2019.10.25

淺原弘嗣. 筋骨格系における力を認識し、形の形成に繋ぐ分子メカニズムの探索. 「認識と形成」研究会2019 2019.09.07

淺原弘嗣. システムアプローチによる関節疾患・先天性骨系統疾患の診断と治療法の開発. 第23回小児分子内分泌研究会 2019.08.04

淺原弘嗣. システムアプローチによる関節疾患・先天性骨系統疾患の診断と治療法の開発. 第92回日本整形外科学会学術総会 2019.05.11

淺原弘嗣. ncRNA ネオタクソノミのための大規模解析基盤の開発. RNAタクソノミ領域会議 2019.02.28

浅原 弘嗣. システムアプローチによるRNA階層での炎症と組織恒常性の分子メカニズムの解明. 東京医科歯科大学基礎系教授の会 2019.01.26

浅原 弘嗣. 骨と骨にまつわる組織の発生と保護と再生. 第25回徳島骨代謝研究会 2018.11.22

浅原 弘嗣. 腱の健康を堅持するための研究. 「認識と形成」研究会2018 2018.09.22

浅原 弘嗣. システムアプローチによる関節疾患・先天性骨系統疾患の診断と治療法の開発. 都医学研究セミナー 2018.09.11

浅原 弘嗣. 骨と軟骨と腱・靭帯の織りなす生理と病理. 第36回日本骨代謝学会学術集会 2018.07.26

淺原弘嗣、伊藤義晃. マイクロRNAによる変形性関節症の病態解明と医療応用. 第4回日本骨免疫学会 2018.06.25

浅原 弘嗣. RNA階層における炎症とがんの病態制御. 第40回日本疼痛学会 2018.06.15

浅原 弘嗣. ゲノム編集技術によって初めて露わにされる生命科学. 日本オミックス医療学会シンポジウム「ゲノム編集に基づく医療の到来」 2018.05.18

浅原 弘嗣. Mkxを介した腱・靱帯のメカノシグナルの調整機構. 第95回日本生理学会大会 2018.03.29

浅原 弘嗣,千葉　朋希. 炎症性サイトカインを制御するRNA結合タンパクの解析. 第40回日本分子生物学会年会 2017.12.09 神戸

浅原 弘嗣. Analysis of RNA-binding protein promoting inflammatory cytokines. 2017年度生命科学系学会合同年次大会 2017.12.09

浅原 弘嗣. Y染色体と生殖. つくば国際会議場 2017.11.26

浅原 弘嗣. RNA階層と分子局在ダイナミクスを包含したシステム医学による炎症性疾患治療と再生医療の開発. 「システムバイオロジーと多階層オミクス～生体分子システム（ネットワーク）の統合的理解から因果関係の予測へ～」 2017.10.09

浅原 弘嗣. マイクロRNAによるリウマチの病態解明と治療法の開発. 愛媛リウマチ研究会 2017.09.16

浅原 弘嗣. 転写からRNA階層を包括した骨・軟骨形成と代謝における遺伝子発現制御機構. 第35回日本骨代謝学会 2017.07.28 福岡

淺原弘嗣. 腱特異的転写因子Mkxの機能解析とバイオ靱帯の創出. 第5回えひめ骨につくなる会 2017.05.25

淺原弘嗣. ncRNAネオタクソノミのための大規模解析基盤の開発. 新学術領域班会議 2017.05.19

淺原弘嗣. 腱特異的転写因子Mkxを介した腱の発生と再生. 第56回日本生体医工学会大会 2017.05.04

淺原　弘嗣. 腱特異的転写因子Mkxのノックアウトラット作成による腱組織の発生・恒常性維持機構の解析. 第10回ＲＲＲ研究会 2017.02.03 京都

浅原弘嗣. DNA methylationと筋分化. 第31回日本整形外科学会基礎学術集会 2016.10.14

浅原弘嗣. Sox9の発言制御機構、第31回日本整形外科学会基礎学術集会. 第31回日本整形外科学会基礎学術集会 2016.10.13 福岡市

浅原弘嗣. ゲノム編集技術と医学研究・難病治療への応用. 日本線維筋痛症学会第8回学術集会 2016.09.18 東京

浅原弘嗣. 腱特異的転写因子Mkxによる腱の健康を堅持するための研究. 「認識と形成」研究会 2016.09.18 名古屋

浅原弘嗣. ゲノム編集技術と医学研究・難病治療への応用. 第44回日本臨床免疫学会総会 2016.09.09

浅原弘嗣、伊藤義晃、千葉朋希、松島隆英、佐藤天平、片岡健輔. Mkxを介した腱・靭帯の分子ネットワークの解析と応用. 学際・国際的高度人材育成　ライフイノベーションマテリアル創製共同研究プロジェクト 2016.07.08

浅原弘嗣、片岡健輔、中道亮、鈴木英嗣、内藤昌志、望月祐輔、幸田直己、森雅樹、篠原正弘、伊藤義晃、嘉山智大. 腱組織の恒常性維持と再生の分子メカニズムの解析. 第2回日本骨免疫学会 2016.07.07

浅原弘嗣. 遺伝子編集技術を応用したリウマチ研究. 千葉大学筑波大学カンファレンス 2016.06.25 東京

浅原弘嗣. 肘関節と遺伝子. 第28回日本肘関節学会学術集会 2016.02.12

浅原弘嗣. 腱の健康を堅持するための研究. 京都府立医科大学整形外科同門会セミナー 2016.02.01 京都

浅原弘嗣. ヒト型量産ロボットによる整形外科の基礎研究. 第18回整形外科アップデートセミナー 2015.10.31 東京

浅原弘嗣. ゲノム編集技術とリウマチ研究への応用. 第2回JCRベーシックリサーチカンファレンス 2015.10.02 東京

浅原弘嗣. RNA 階層における慢性炎症の分子機序の解析. 第16回運動器科学研究会 2015.09.12 鹿児島

浅原弘嗣. Rp58とMkxによる筋・腱・靭帯の形成機構. 第1回日本筋学会学術集会 2015.08.08 東京

浅原弘嗣. MicroRNAの腫瘍形成における機能の解析. 第1回日本骨免疫学会 2015.07.02 宮古島

浅原 弘嗣. RNAの階層における軟骨の分化と恒常性の制御機構. 第28回日本軟骨代謝学会 2015.03.06 東京医科歯科大学

浅原 弘嗣, 佐藤 天平, 乾 雅史. The critical role of miRNAs at the edge of Hox-code during skeletal development. 第37回日本分子生物学会年会 2014.11.27 神奈川

浅原 弘嗣. ゲノム編集技術による軟骨発生メカニズムと関節炎の解析. 第12回RCGMフロンティア国際シンポジウム 2014.10.31 埼玉

浅原 弘嗣. ゲノム編集技術による骨格・関節のメカニズムと関節炎病態の解析. 北大遺伝子病制御研究所・金沢大がん進展制御研究所ジョイントシンポジウム 2014.10.27 北海道

Hiroshi Asahara. Analysis of miRNAs in cartilage by TALEN/CRISPR genome editing techniques. 7th International Conference on Osteoporosis and Bone Research,2014 2014.10.16 杭州

浅原 弘嗣. 軟骨の発生・再生とノンコーディングRNA. 第29回日本整形外科学会基礎学術集会 2014.10.09 鹿児島

浅原 弘嗣. 炎症をRNA階層で制御する分子機構の解析. 認識と形成2014 2014.09.14 熊本

浅原 弘嗣. RNA階層における慢性炎症制御機構の解析. さきがけ「炎症の慢性化機構の解明と制御」研究領域第7回領域会議 2014.08.24 北海道

浅原 弘嗣. ゲノム編集技術による遺伝子治療の可能性. 第35回日本炎症・再生医学会 2014.07.02 沖縄

浅原 弘嗣. 整形外科学における分子生物学の発展と展望. 第122回中部日本整形外科災害外科学会・学術集会 2014.04.12 岡山

浅原 弘嗣. 軟骨とマイクロRNA (It’s NOT a small world). 第27回日本軟骨代謝学会 2014.02.28 京都

浅原 弘嗣. ｍｉＲＮＡの成熟制御によるＲＮＡネットワークの解明. 平成25年度「非コードRNA作用マシナリー」領域会議 2014.01.09 福島