Personnel Information

写真a

ASAHARA Hiroshi


Job title

Professor

Mail Address

asahara.syst@tmd.ac.jp

Research Areas, Keywords

Basic Medicine, Molecular Biology, Developmental Regenerative Medicine, System Biology, Orthopedic Surgery, Rheumatology
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Graduating School 【 display / non-display 】

  • Okayama University, Faculty of Medicine, 1992.03, Graduated

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Graduate School 【 display / non-display 】

  • Okayama University, Graduate School, Division of Medicine, Doctor's Course, 1997.03, Completed

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Campus Career 【 display / non-display 】

  • 2011.06
    -
    Now
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Advanced Therapeutic Sciences， Systems BioMedicine， Professor
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External Career 【 display / non-display 】

  • 2004
    -
    2010
    , Director
  • 1992
    -
    1997
    , Senior Resident
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Research Areas 【 display / non-display 】

  • Molecular biology

  • System genome science

  • Developmental biology

  • Orthopaedic surgery

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Qualification Acquired 【 display / non-display 】

  • Doctor

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Published Papers & Misc 【 display / non-display 】

  • Momo Isobe, Hikaru Toya, Mari Mito, Tomoki Chiba, Hiroshi Asahara, Tetsuro Hirose, Shinichi Nakagawa. Forced isoform switching of Neat1_1 to Neat1_2 leads to the loss of Neat1_1 and the hyperformation of paraspeckles but does not affect the development and growth of mice. RNA. 2019.12; ( PubMed, DOI )

  • Carmen Adriaens, Florian Rambow, Greet Bervoets, Toomas Silla, Mari Mito, Tomoki Chiba, Hiroshi Asahara, Tetsuro Hirose, Shinichi Nakagawa, Torben Heick Jensen, Jean-Christophe Marine. The long noncoding RNA NEAT1_1 is seemingly dispensable for normal tissue homeostasis and cancer cell growth. RNA. 2019.12; 25 (12): 1681-1695. ( PubMed, DOI )

  • Yutaro Uchida, Tomoki Chiba, Ryota Kurimoto, Hiroshi Asahara. Post-transcriptional regulation of inflammation by RNA-binding proteins via cis-elements of mRNAs. J. Biochem.. 2019.11; 166 (5): 375-382. ( PubMed, DOI )

  • Satoshi Yamashita, Kensuke Kataoka, Hiroto Yamamoto, Tomoko Kato, Satoshi Hara, Katsushi Yamaguchi, Claire Renard-Guillet, Yuki Katou, Katsuhiko Shirahige, Haruki Ochi, Hajime Ogino, Tokujiro Uchida, Masafumi Inui, Shuji Takada, Shuji Shigenobu, Hiroshi Asahara. Comparative analysis demonstrates cell type-specific conservation of SOX9 targets between mouse and chicken. Sci Rep. 2019.08; 9 (1): 12560. ( PubMed, DOI )

  • Sho Mokuda, Ryo Nakamichi, Tokio Matsuzaki, Yoshiaki Ito, Tempei Sato, Kohei Miyata, Masafumi Inui, Merissa Olmer, Eiji Sugiyama, Martin Lotz, Hiroshi Asahara. Wwp2 maintains cartilage homeostasis through regulation of Adamts5. Nat Commun.. 2019.06; 10 (1): 2429. ( PubMed, DOI, ichushi )

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Books etc 【 display / non-display 】

  • Mokuda Sho, Olmer Merissa, Lotz Martin K., Sugiyama Eiji, Asahara Hiroshi . 骨と軟骨の生物学　WWドメイン含有タンパク質2(Wwp2)はmiR-140と協働して軟骨の恒常性を維持する(Bone and Cartilage Biology　WW domain-containing protein 2(Wwp2) maintains cartilage homeostasis in coordination with miR-140) . (一社)日本リウマチ学会， 2019.03

  • Ito Y, Mokuda S, Miyata K, Matsushima T, Asahara H*. . Chronic Inflammation (Chapter 6). Springer， 2016.11 MicroRNAs in Chronic Inflammation Diseases.

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Conference Activities & Talks 【 display / non-display 】

  • 淺原弘嗣. Lecture I“Cartilage homeostasis and arthritis pathogenesis via RNA regulation”. 16th Meeting of Bone Biology Forum 2019.08.16

  • 浅原弘嗣 、茂久田翔、伊藤義晃、中道亮、杉山英二 、松崎時夫. Wwp2 maintains cartilage homeostasis through regulation of Adamts5. 第5回日本骨免疫学会 2019.06.26

  • Hiroshi Asahara, Sho Mokuda, Yoshiaki Ito, Masafumi Inui, Ryo Nakamichi, Tomoki Chiba, Ryota Kurimoto, Takahide Matsushima. miRNAs in arthritis pathogenesis and therapy. The 24th Annual Meeting of the RNA Society 2019.06.14

  • Hiroshi Asahara. miRNAs in arthritis pathogenesis and therapy. 2019 Keystone Symposia Conference 2019.04.17

  • 淺原弘嗣. 腱・靭帯のメカノプロパティを応用した再生医療. FAOPS2019 2019.03.31

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