Personnel Information

写真a

ASAHARA Hiroshi


Job title

Professor

Mail Address

asahara.syst@tmd.ac.jp

Research Areas, Keywords

Basic Medicine, Molecular Biology, Developmental Regenerative Medicine, System Biology, Orthopedic Surgery, Rheumatology
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Graduating School 【 display / non-display 】

  • Okayama University, Faculty of Medicine, 1992.03, Graduated

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Graduate School 【 display / non-display 】

  • Okayama University, Graduate School, Division of Medicine, Doctor's Course, 1997.03, Completed

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Campus Career 【 display / non-display 】

  • 2011.06
    -
    2020.06
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Advanced Therapeutic Sciences， Systems BioMedicine， Professor
  • 2020.07
    -
    Now
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Advanced Therapeutic Sciences， Systems BioMedicine， Professor
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External Career 【 display / non-display 】

  • 2004
    -
    2010
    , Director
  • 1992
    -
    1997
    , Senior Resident
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Research Areas 【 display / non-display 】

  • System genome science

  • Developmental biology

  • Orthopaedic surgery

  • Molecular biology

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Qualification Acquired 【 display / non-display 】

  • Doctor

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Published Papers & Misc 【 display / non-display 】

  • Yutaro Uchida, Takahide Matsushima, Ryota Kurimoto, Tomoki Chiba, Yuki Inutani, Hiroshi Asahara. Identification of chemical compounds regulating PD-L1 by introducing HiBiT-tagged cells. FEBS Lett. 2021.03; 595 (5): 563-576. ( PubMed, DOI )

  • Tomoki Chiba, Ryota Kurimoto, Takahide Matsushima, Yoshiaki Ito, Ryo Nakamichi, Martin Lotz, Hiroshi Asahara. MicroRNA Expression Profiling, Target Identification, and Validation in Chondrocytes. Methods Mol Biol. 2021; 2245 151-166. ( PubMed, DOI )

  • Kwang Il Lee, Ramya Gamini, Merissa Olmer, Yasunari Ikuta, Joe Hasei, Jihye Baek, Oscar Alvarez-Garcia, Shawn P Grogan, Darryl D D'Lima, Hiroshi Asahara, Andrew I Su, Martin K Lotz. Mohawk is a transcription factor that promotes meniscus cell phenotype and tissue repair and reduces osteoarthritis severity. Sci Transl Med. 2020.10; 12 (567): ( PubMed, DOI )

  • Ryota Kurimoto, Tomoki Chiba, Yoshiaki Ito, Takahide Matsushima, Yuki Yano, Kohei Miyata, Yuka Yashiro, Tsutomu Suzuki, Kozo Tomita, Hiroshi Asahara. The tRNA pseudouridine synthase TruB1 regulates the maturation of let-7 miRNA. EMBO J. 2020.10; 39 (20): e104708. ( PubMed, DOI )

  • Ryo Nakamichi, Ryota Kurimoto, Yusuke Tabata, Hirosi Asahara. Transcriptional, epigenetic and microRNA regulation of growth plate. Bone. 2020.08; 137 115434. ( PubMed, DOI )

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Books etc 【 display / non-display 】

  • Mokuda Sho, Olmer Merissa, Lotz Martin K., Sugiyama Eiji, Asahara Hiroshi . 骨と軟骨の生物学　WWドメイン含有タンパク質2(Wwp2)はmiR-140と協働して軟骨の恒常性を維持する(Bone and Cartilage Biology　WW domain-containing protein 2(Wwp2) maintains cartilage homeostasis in coordination with miR-140) . (一社)日本リウマチ学会， 2019.03

  • Ito Y, Mokuda S, Miyata K, Matsushima T, Asahara H*. . Chronic Inflammation (Chapter 6). Springer， 2016.11 MicroRNAs in Chronic Inflammation Diseases.

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Conference Activities & Talks 【 display / non-display 】

  • 松島隆英、淺原弘嗣. Localizatome Project:タンパク質の網羅的細胞内ダイナミクス解析. 第43回日本分子生物学会 2020.12.02 web

  • Ryota KURIMOTO, Hiroshi ASAHARA. The tRNA pseudouridine synthase TruB1 regulates the maturation of let-7 miRNA. 2nd RNAJ Online Meeting ~ mRNA/miRNA Metabolism ~ 2020.08.27 web

  • Ryota Kurimoto, Hiroshi Asahara. The tRNA pseudouridine synthase TruB1 regulates the maturation of let-7 miRNA.. 第2回RNAJオンラインミーティング 2020.08.27 Tokyo

  • Hiroshi Asahara. Mechano-signal on tendon and ligament homeostasis via Mkx. International Symposium on AMED “Mechanobiology” Project 2020.02.08

  • Hiroshi Asahara. Mechano-signal Pathway Regulating Tendon and Ligament Via Mkx. AMED革新的先端研究開発支援事業（AMED-CREST,PRIME）「メカノバイオ」領域　令和元年度　領域会議 2020.02.06

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Awards & Honors 【 display / non-display 】

  • Catalyst Award，Healthy Longevity Global Competition，2020.10

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