Graduate School 【 display / non-display 】

Graduate School 【 display / non-display 】

• Tohoku University, Graduate School, Division of Medical Sciences, Department of Virology, Doctor's Course, 2003.03, Completed

Degree 【 display / non-display 】

Degree 【 display / non-display 】

• Ph.D, Tohoku University

Campus Career 【 display / non-display 】

Campus Career 【 display / non-display 】

• 2011.03

  -

  2018.03

  Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Environmental Response， Molecular Virology， Assistant Professor
• 2017.08

  -

  2018.03

  Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Environmental Response， Molecular Virology， Junior Associate Professor
• 2018.04

  -

  2020.05

  Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Environmental Response， Molecular Virology， Junior Associate Professor
• 2020.05

  -

  Now

  Tokyo Medical and Dental University， Medical Hospital， Advisor to the Director
• 2020.06

  -

  2021.03

  Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Environmental Response， Molecular Virology， Junior Associate Professor

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External Career 【 display / non-display 】

External Career 【 display / non-display 】

• 2007.01

  -

  2011.02

  , Project Assistant Professor
• 2010.04

  -

  2011.03

  , Visiting Lecturer

Academic Activity 【 display / non-display 】

Academic Activity 【 display / non-display 】

• 2021.03

  -

  Now

  Frontiers in Virology (Fundarmental Virology) Associate Editor
• 2018.01

  -

  Now

  Microbiology and Immunology Associate Editor
• 2010.01

  -

  Now

  Frontiers in Microbiology Review Editor
• 2021.01

  -

  Now

  The Japanese Society for Virology Councilor

Research Areas 【 display / non-display 】

Research Areas 【 display / non-display 】

• Virology

Research Theme 【 display / non-display 】

Research Theme 【 display / non-display 】

• Creation of new druggable target to overcome HIV-1 latency via innovative fusion between high-resolution nucleic acid analysis and leading-edge technique for viral dynamics, 2019.04 - Now

  Keyword： HIV Cure
  State： Collaboration in Japan
  

• Research on the development of anti-HIV drugs with a novel mechanism of action to cure HIV, 2018.04 - Now

  Keyword： HIV latency
  State： Collaboration in Japan
  

Published Papers & Misc 【 display / non-display 】

Published Papers & Misc 【 display / non-display 】

• Lotfi S, Nasser H, Noyori O, Hiyoshi M, Takeuchi H, Koyanagi Y, Suzu S. M-Sec facilitates intercellular transmission of HIV-1 through multiple mechanisms. Retrovirology. 2020.07; 17 (1): 20. ( PubMed, DOI )

• Weitong Yao, Takeshi Yoshida, Saki Hashimoto, Hiroaki Takeuchi, Klaus Strebel, Shoji Yamaoka. Vpu of a Simian Immunodeficiency Virus Isolated from Greater Spot-Nosed Monkey Antagonizes Human BST-2 via Two AxxxxxxxW Motifs. J. Virol.. 2020.01; 94 (2): ( PubMed, DOI )

• H. Takeuchi, T. Ishida, Y. Satou, J. Gohda, H. Kitamura, S. Gan, K. Takahashi, S. Yamaoka. Genome-wide RNAi screen identifies MAPK-RPK required for HIV-1 proviral silencing in non-T cell reservoir cell-line model Journal of Virus Eradication. 2019.12; 5 (Supplement 3): 5. ( DOI )

• Iwase CS., Miyazato P., Katsuya H., Islam S., Yang TJS., Ito J., Matsuo M., Takeuchi H., Ishida T., Matsuda K., Maeda K., and Satou Y.. HIV-1 DNA-capture-seq is a useful tool for the comprehensive characterization of HIV-1 provirus. Scientific Reports. 2019.08; 9 (1): 12326. ( DOI )

• Maeda K., Das D., Kobayakawa T., Tamamura H., and Takeuchi H. Discovery and Development of anti-HIV Therapeutic Agents: Progress Towards Improved HIV Medication. Current Topics in Medicinal Chemistry. 2019.07; 19 1-29. ( DOI )

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Books etc 【 display / non-display 】

Books etc 【 display / non-display 】

• Sakuma R and Takeuchi H. Retroviral Host Cell Factors: APOBEC3G, TRIM5, and Cyclophilins.. 2011.11 (ISBN : 978-953-307-665-2)

Conference Activities & Talks 【 display / non-display 】

Conference Activities & Talks 【 display / non-display 】

• Ishida T, Satou Y, Gohda J, Kitamura H, Gan S, Takahashi K, Yamaoka S, and Takeuchi H.. Genome-wide RNAi screen identifies MAPK-RPK required for HIV-1 proviral silencing in non-T cell reservoir cell-line model.. The 9th international workshop on HIV persistence during therapy 2019.12.10 Miami, USA

• Takeuchi Hiroaki. Multiple approach to HIV cure: Towards a better understanding of the precise cellular regulation of HIV-1 infection.. France-Japan Symposium on HIV and hepatitis basic research 2019.10 Paris, France

• Hiroaki Takeuchi. Dynamics and Regulation of HIV-1 Uncoating and Nuclear Movements of HIV-1 Complexes: Our Recent Advances and Future Perspectives.. CAIDS/ACC/ARC Joint Symposium 2018.11.10 東京

• 武内　寛明. Dynamics and regulation of HIV-1 uncoating and nuclear movements of HIV-1 complexes. 熊本大学エイズ学研究センター「エイズ学演習VI」大学院セミナー 2018.07.25 熊本、日本

• Hiroaki Takeuchi. The timing and triggering of uncoating in an early stage of HIV-1 infection: the essential role of MELK for optimal capsid core disassembly. Special AMR seminar at St. Vincent's Centre of Applied Medical Research 2017.09.27 Sydney, Australia

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Awards & Honors 【 display / non-display 】

Awards & Honors 【 display / non-display 】

• The Fellows Award for Research Excellence (FARE) of National Institutes of Health (NIH), USA，2006

• The Fellows Award for Research Excellence (FARE) of National Institutes of Health (NIH), USA，2005

Campus class subject 【 display / non-display 】

Campus class subject 【 display / non-display 】

• Basic Microbiology，2011 - Now