Personnel Information

写真a

NAGAISHI Takashi


Job title

Associate Professor

Laboratory Address

Tokyo Medical and Dental University, Dept. Gastroenterology 1-5-45 Yushima, Bunkyo-ku Tokyo 113-8519, Japan

Mail Address

The inquiry by e-mail is 《here

Campus Career 【 display / non-display

  • 2007.04
    -
    2009.05
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Endowed Departments, Department of Advanced Therapeutics for GI Diseases, Assistant Professor
  • 2009.06
    -
    2010.01
    Tokyo Medical and Dental University, Medical Hospital, Hospital Departments, Department of Internal Medicine, Gastroenterology and Hepatology, Assistant Professor
  • 2017.04
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Endowed Departments, Department of Advanced Therapeutics for GI Diseases, Associate Professor

External Career 【 display / non-display

  • 2000-2003 Postdoc, Div. Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA,
  • 2003-2006 Research Associate, Div. Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA,
  • 2006-2007 Medical Fellow, Dep. Gastroenterology, Tokyo Medical and Detal University, Tokyo, Japan,
  • 2007-current Assictant Professor, Dep. Gastroenterology, Tokyo Medical and Detal University Graduate School of Medical Science, Tokyo, Japan,

Academic Activity 【 display / non-display

  • 2003-2006 Research Fellowship, Crohn and Colitis Foundation of America
 

Published Papers & Misc 【 display / non-display

  • Yuria Takei, Yasuhiro Nemoto, Ryo Morikawa, Shohei Tanaka, Shigeru Oshima, Takashi Nagaishi, Ryuichi Okamoto, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe. T cells show amoeboid shape and frequent morphological change in vitro, and localize to small intestinal intraepithelial region in vivo. Biochem. Biophys. Res. Commun.. 2020.03; 523 (2): 328-335. ( PubMed, DOI )

  • Shohei Tanaka, Yasuhiro Nemoto, Yuria Takei, Ryo Morikawa, Shigeru Oshima, Takashi Nagaishi, Ryuichi Okamoto, Kiichiro Tsuchiya, Tetsuya Nakamura, Susanne Stutte, Mamoru Watanabe. High-fat diet-derived free fatty acids impair the intestinal immune system and increase sensitivity to intestinal epithelial damage. Biochem Biophys Res Commun. 2020.02; 522 (4): 971-977. ( PubMed, DOI )

  • Takashi Nagaishi, Daiki Yamada, Kohei Suzuki, Ryosuke Fukuyo, Eiko Saito, Masayoshi Fukuda, Taro Watabe, Naoya Tsugawa, Kengo Takeuchi, Kouhei Yamamoto, Ayako Arai, Kazuo Ohtsuka, Mamoru Watanabe. Indolent T cell lymphoproliferative disorder with villous atrophy in small intestine diagnosed by single-balloon enteroscopy. Clin J Gastroenterol. 2019.10; 12 (5): 434-440. ( PubMed, DOI )

  • Taro Watabe, Takashi Nagaishi, Naoya Tsugawa, Yudai Kojima, Nisha Jose, Akinori Hosoya, Michio Onizawa, Yasuhiro Nemoto, Shigeru Oshima, Tetsuya Nakamura, Hajime Karasuyama, Takahiro Adachi, Mamoru Watanabe. B cell activation in the cecal patches during the development of an experimental colitis model. Biochem. Biophys. Res. Commun.. 2018.02; 496 (2): 367-373. ( PubMed, DOI )

  • Yoichi Nibe, Shigeru Oshima, Masanori Kobayashi, Chiaki Maeyashiki, Yu Matsuzawa, Kana Otsubo, Hiroki Matsuda, Emi Aonuma, Yasuhiro Nemoto, Takashi Nagaishi, Ryuichi Okamoto, Kiichiro Tsuchiya, Tetsuya Nakamura, Shinichiro Nakada, Mamoru Watanabe. Novel polyubiquitin imaging system, PolyUb-FC, reveals that K33-linked polyubiquitin is recruited by SQSTM1/p62. Autophagy. 2018.01; 1-43. ( PubMed, DOI )

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Books etc 【 display / non-display

  • Nagaishi T, Watanabe M. Crohn's Disease and Ulcerative Colitis: from Epidemiology and Immunobiology to a Rational Diagnostic and Therapeutic Approach. 2017.03 Paradigm of T cell differentiation in IBD: Crohn's disease and ulcerative colitis (ISBN : 978-3-319-33701-2)

Conference Activities & Talks 【 display / non-display

  • Takashi Nagaishi, Naoya Tsugawa, Daiki Yamada, Taro Watabe, Michio Onizawa, Mamoru Watanabe. B cell receptor signaling in lymphoid tissues may be regulated by CEACAM1.. ECCO2020 2020.02.14 Vienna(Austria)

  • Takahiro Adachi, Taro Watabe, Takashi Nagaishi, Mamoru Watanabe, Hajime Karasuyama, Soichiro Yoshikawa. IgA-deficiency causes spontaneous enteritis.. The 48th Annual Meeting of the Japanese Society for Immunology 2019.12.13 Hamamatsu(Japan)

  • Naoya Tsugawa, Takashi Nagaishi, Daiki Yamada, Toshimitsu Fujii, Yudai Kojima, Arisa Tokai, Taro Watabe, Shuang Wang, Michio Onizawa, Takahiro Adachi, Mamoru Watanabe. BCR signaling in the activated B cells may be regulated by the long isoform of Ceacam1. 第48回日本免疫学会学術集会 2019.12.11 アクトシティ浜松

  • Daiki Yamada, Takashi Nagaishi, Taro Watabe, Naoya Tsugawa, Yudai Kojima, Takahiro Adachi, Mamoru Watanabe. Analysis of Ileocecal Immune Response in an Animal Model of Colitis. ICMI 2019 2019.07.17 Brisbane Convention & Exhibition Centre(Brisbane)

  • Takashi Nagaishi, Yudai Kojima, Taro Watabe, Naoya Tsugawa, Daiki Yamada, Nisha Jose, Akinori Hosoya, Masahiro Suzuki, Michio Onizawa, Mamoru Watanabe. Analysis of APL expression in an animal model of chronic colitis. FOCIS2019 2019.06.20 Boston(USA)

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