Yuria Takei, Yasuhiro Nemoto, Ryo Morikawa, Shohei Tanaka, Shigeru Oshima, Takashi Nagaishi, Ryuichi Okamoto, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe. T cells show amoeboid shape and frequent morphological change in vitro, and localize to small intestinal intraepithelial region in vivo. Biochem. Biophys. Res. Commun.. 2020.03; 523 (2): 328-335. ( PubMed, DOI )

Shohei Tanaka, Yasuhiro Nemoto, Yuria Takei, Ryo Morikawa, Shigeru Oshima, Takashi Nagaishi, Ryuichi Okamoto, Kiichiro Tsuchiya, Tetsuya Nakamura, Susanne Stutte, Mamoru Watanabe. High-fat diet-derived free fatty acids impair the intestinal immune system and increase sensitivity to intestinal epithelial damage. Biochem Biophys Res Commun. 2020.02; 522 (4): 971-977. ( PubMed, DOI )

Takashi Nagaishi, Daiki Yamada, Kohei Suzuki, Ryosuke Fukuyo, Eiko Saito, Masayoshi Fukuda, Taro Watabe, Naoya Tsugawa, Kengo Takeuchi, Kouhei Yamamoto, Ayako Arai, Kazuo Ohtsuka, Mamoru Watanabe. Indolent T cell lymphoproliferative disorder with villous atrophy in small intestine diagnosed by single-balloon enteroscopy. Clin J Gastroenterol. 2019.10; 12 (5): 434-440. ( PubMed, DOI )

Taro Watabe, Takashi Nagaishi, Naoya Tsugawa, Yudai Kojima, Nisha Jose, Akinori Hosoya, Michio Onizawa, Yasuhiro Nemoto, Shigeru Oshima, Tetsuya Nakamura, Hajime Karasuyama, Takahiro Adachi, Mamoru Watanabe. B cell activation in the cecal patches during the development of an experimental colitis model. Biochem. Biophys. Res. Commun.. 2018.02; 496 (2): 367-373. ( PubMed, DOI )

Yoichi Nibe, Shigeru Oshima, Masanori Kobayashi, Chiaki Maeyashiki, Yu Matsuzawa, Kana Otsubo, Hiroki Matsuda, Emi Aonuma, Yasuhiro Nemoto, Takashi Nagaishi, Ryuichi Okamoto, Kiichiro Tsuchiya, Tetsuya Nakamura, Shinichiro Nakada, Mamoru Watanabe. Novel polyubiquitin imaging system, PolyUb-FC, reveals that K33-linked polyubiquitin is recruited by SQSTM1/p62. Autophagy. 2018.01; 1-43. ( PubMed, DOI )

Jianbo An, Takashi Nagaishi, Taro Watabe, Taeko K Naruse, Mamoru Watanabe, Akinori Kimura. MKL1 expressed in macrophages contributes to the development of murine colitis. Sci Rep. 2017.10; 7 (1): 13650. ( PubMed, DOI )

Chiaki Maeyashiki, Shigeru Oshima, Kana Otsubo, Masanori Kobayashi, Yoichi Nibe, Yu Matsuzawa, Michio Onizawa, Yasuhiro Nemoto, Takashi Nagaishi, Ryuichi Okamoto, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe. HADHA, the alpha subunit of the mitochondrial trifunctional protein, is involved in long-chain fatty acid-induced autophagy in intestinal epithelial cells. Biochem. Biophys. Res. Commun.. 2017.03; 484 (3): 636-641. ( PubMed, DOI )

Masanori Kobayashi, Shigeru Oshima, Chiaki Maeyashiki, Yoichi Nibe, Kana Otsubo, Yu Matsuzawa, Yasuhiro Nemoto, Takashi Nagaishi, Ryuichi Okamoto, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe. The ubiquitin hybrid gene UBA52 regulates ubiquitination of ribosome and sustains embryonic development. Sci Rep. 2016.11; 6 36780. ( PubMed, DOI )

Kazuo Ohtsuka, Kento Takenaka, Yoshio Kitazume, Toshimitsu Fujii, Katsuyoshi Matsuoka, Maiko Kimura, Takashi Nagaishi, Mamoru Watanabe. Magnetic resonance enterography for the evaluation of the deep small intestine in Crohn's disease. Intest Res. 2016.04; 14 (2): 120-126. ( PubMed, DOI )

Takashi Nagaishi, Taro Watabe, Nisha Jose, Arisa Tokai, Toshimitsu Fujii, Katsuyoshi Matsuoka, Masakazu Nagahori, Kazuo Ohtsuka, Mamoru Watanabe. Epithelial Nuclear Factor-κB Activation in Inflammatory Bowel Diseases and Colitis-Associated Carcinogenesis. Digestion. 2016.01; 93 (1): 40-46. ( PubMed, DOI )

Yu Matsuzawa, Shigeru Oshima, Masahiro Takahara, Chiaki Maeyashiki, Yasuhiro Nemoto, Masanori Kobayashi, Yoichi Nibe, Kengo Nozaki, Takashi Nagaishi, Ryuichi Okamoto, Kiichiro Tsuchiya, Tetsuya Nakamura, Averil Ma, Mamoru Watanabe. TNFAIP3 promotes survival of CD4 T cells by restricting MTOR and promoting autophagy. Autophagy. 2015.06; 0. ( PubMed, DOI )

Keita Fukushima, Kiichiro Tsuchiya, Yoshihito Kano, Nobukatsu Horita, Shuji Hibiya, Ryohei Hayashi, Keisuke Kitagaki, Mariko Negi, Eisaku Itoh, Takumi Akashi, Yoshinobu Eishi, Shigeru Oshima, Takashi Nagaishi, Okamoto Ryuichi, Tetsuya Nakamura, Mamoru Watanabe. Atonal homolog 1 protein stabilized by tumor necrosis factor α induces high malignant potential in colon cancer cell line. Cancer Sci.. 2015.05; ( PubMed, DOI )

Yu Matsuzawa, Shigeru Oshima, Yoichi Nibe, Masanori Kobayashi, Chiaki Maeyashiki, Yasuhiro Nemoto, Takashi Nagaishi, Ryuichi Okamoto, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe. RIPK3 regulates p62-LC3 complex formation via the caspase-8-dependent cleavage of p62. Biochem. Biophys. Res. Commun.. 2015.01; 456 (1): 298-304. ( PubMed, DOI )

Masahiro Suzuki, Takashi Nagaishi, Motomi Yamazaki, Michio Onizawa, Taro Watabe, Yuriko Sakamaki, Shizuko Ichinose, Mamoru Totsuka, Shigeru Oshima, Ryuichi Okamoto, Motoyuki Shimonaka, Hideo Yagita, Tetsuya Nakamura, Mamoru Watanabe. Myosin light chain kinase expression induced via tumor necrosis factor receptor 2 signaling in the epithelial cells regulates the development of colitis-associated carcinogenesis. PLoS ONE. 2014.02; 9 (2): e88369. ( PubMed, DOI )

Tomohiro Mizutani, Tetsuya Nakamura, Ryo Morikawa, Masayoshi Fukuda, Wakana Mochizuki, Yuhki Yamauchi, Kengo Nozaki, Shiro Yui, Yasuhiro Nemoto, Takashi Nagaishi, Ryuichi Okamoto, Kiichiro Tsuchiya, Mamoru Watanabe. Real-time analysis of P-glycoprotein-mediated drug transport across primary intestinal epithelium three-dimensionally cultured in vitro. Biochem. Biophys. Res. Commun.. 2012.03; 419 (2): 238-243. ( PubMed, DOI )

Takashi Nagaishi, Naoya Tsugawa, Daiki Yamada, Yudai Kojima, Michio Onizawa, Taro Watabe, Richard S. Blumberg, Mamoru Watanabe. BCR signaling in lymphoid tissues regulated by the long isoform of Ceacam1.. FOCIS2020 2020.10.28 Web開催

Takashi Nagaishi, Daiki Yamada, Naoya Tsugawa, Taro Watabe, Eiko Saito, Masayoshi Fukuda, Ayako Arai, Kazuo Ohtsuka, Mamoru Watanabe. A case of villous atrophy with CCR4+ T cell infiltration in the small intestine.. UEGW2020 2020.10.10 Web開催

Takashi Nagaishi, Naoya Tsugawa, Daiki Yamada, Taro Watabe, Michio Onizawa, Yudai Kojima, Richard S. Blumberg, Mamoru Watanabe. BCR signaling in lymphoid tissues is regulated by the long isoform of Ceacam1.. MICS2020 2020.07.20 Web開催

Takashi Nagaishi, Naoya Tsugawa, Daiki Yamada, Taro Watabe, Michio Onizawa, Mamoru Watanabe. B cell receptor signaling in lymphoid tissues may be regulated by CEACAM1.. ECCO2020 2020.02.14 Vienna（Austria）

Takahiro Adachi, Taro Watabe, Takashi Nagaishi, Mamoru Watanabe, Hajime Karasuyama, Soichiro Yoshikawa. IgA-deficiency causes spontaneous enteritis.. The 48th Annual Meeting of the Japanese Society for Immunology 2019.12.13 Hamamatsu（Japan）

Naoya Tsugawa, Takashi Nagaishi, Daiki Yamada, Toshimitsu Fujii, Yudai Kojima, Arisa Tokai, Taro Watabe, Shuang Wang, Michio Onizawa, Takahiro Adachi, Mamoru Watanabe. BCR signaling in the activated B cells may be regulated by the long isoform of Ceacam1. 第48回日本免疫学会学術集会 2019.12.11 アクトシティ浜松

Daiki Yamada, Takashi Nagaishi, Taro Watabe, Naoya Tsugawa, Yudai Kojima, Takahiro Adachi, Mamoru Watanabe. Analysis of Ileocecal Immune Response in an Animal Model of Colitis. ICMI 2019 2019.07.17 Brisbane Convention & Exhibition Centre(Brisbane)

Takashi Nagaishi, Yudai Kojima, Taro Watabe, Naoya Tsugawa, Daiki Yamada, Nisha Jose, Akinori Hosoya, Masahiro Suzuki, Michio Onizawa, Mamoru Watanabe. Analysis of APL expression in an animal model of chronic colitis. FOCIS2019 2019.06.20 Boston（USA）

Daiki Yamada, Takashi Nagaishi, Yudai Kojima, Taro Watabe, Naoya Tsugawa, Nisha Jose, Akinori Hosoya, Masahiro Suzuki, Michio Onizawa, Mamoru Watanabe. APL downregulation in an animal model of chronic colitis. AOCC2019 2019.06.15 Taipei Marriott Hotel

Takashi Nagaishi, Yudai Kojima, Daiki Yamada, Taro Watabe, Naoya Tsugawa, Nisha Jose, Michio Onizawa, Mamoru Watanabe.. APL expression is downregulated in an animal model of chronic colitis.. ECCO2019 2019.03.08 Copenhagen（Denmark）

Yudai Kojima, Takashi Nagaishi, Taro Watabe, Daiki Yamada, Naoya Tsugawa, Nisha Jose, Akinori Hosoya, Masahiro Shimizu, Michio Onizawa, Mamoru Watanabe. Downregulated APL expression in T cells in the setting of chronic colitis. 第47回日本免疫学会学術集会 2018.12.10 福岡国際会議場（福岡県福岡市）

Jianbo An, Takashi Nagaishi, Taro Watabe, Taeko K. Naruse, Mamoru Watanabe, Akinori Kimura. Mice overexpressing MKL1 in macrophages experience fulminant colitis. UEGW 2018 2018.10.22 Vienna（Austria）

Yudai Kojima, Takashi Nagaishi, Taro Watabe, Naoya Tsugawa, Nisha Jose, Daiki Yamada, Akinori Hosoya, Takahiro Adachi, Mamoru Watanabe. B cell-mediated ileocecal immune response is activated in the early phase of colitis development. UEGW 2018 2018.10.22 Vienna（Austria）

Jianbo An, Takashi Nagaishi, Taro Watabe, Taeko K. Naruse, Mamoru Watanabe, Akinori Kimura. Overexpression of MKL1 in Macrophages leads to the development of murine colitis. MICS 2018 2018.07.19 Oxford（UK）

Jianbo An, Takashi Nagaishi, Taro Watabe, Taeko K. Naruse, Mamoru Watanabe, Akinori Kimura. Mice overexpressing MKL1 in macrophages are susceptible to DSS-induced colitis. FOCIS 2018 2018.06.22 San Francisco (USA）

Takashi Nagaishi, Taro Watabe, Tsugawa, Yudai Kojima, Nisha Jose, Daiki Yamada, Takahiro Adachi, Mamoru Watanabe. Analysis of cecal immune response in a murine model of colitis using intravital imaging. FOCIS 2018 2018.06.20 San Francisco (USA）

Jianbo An, Takashi Nagaishi, Taro Watabe, Taeko K. Naruse, Mamoru Watanabe, Akinori Kimura. Mice overexpressing MKL1 in macrophages are susceptible to the development of colitis. DDW 2018 2018.06.05 Washington D.C (USA）

Taro Watabe, Takashi Nagaishi, Naoya Tsugawa, Yudai Kojima, Nisha Jose, Akinori Hosoya, Takahiro Adachi, Mamoru Watanabe. Analysis of ileocecal immune response in an animal model of colitis using intra-vital imaging. DDW 2018 2018.06.05 Washington D.C (USA）

Watabe T, Nagaishi T, Hosoya A, Jose N, Tsugawa N, Kojima Y, Yoshikawa S, Karasuyama H, Adachi T, Watanabe M . Analysis of ileocecal immune response in an experimental colitis model using intra-vital imaging. The 46th Annual Meeting of The Japanese Society for Immunology 2017.12.14 Miyagi (Japan)

Tsugawa N, Nagaishi T, Watabe T, Hosoya A, Jose N, Kojima Y, Yoshikawa S, Karasuyama H, Adachi T, Watanabe M. Verification of immunoglobulin A regulation of mucosal microflora and homeostasis. The 46th Annual Meeting of The Japanese Society for Immunology 2017.12.14 Miyagi (Japan)

Chiba A, Nagaishi T, Miyake S. MAIT cells exacerbate the disease course of oxazolone-induced colitis. CD1-MR1 2017 2017.11.05 California (USA)

N. Tsugawa T. Nagaishi T. Watabe N. Jose A. Hosoya Y. Kojima T. Adachi R. Blumberg M. Watanabe. Verification of immunoglobulin a regulation of microflora and protection of intestinal mucosa. UEGW2017 (欧州消化器病学会週間2017） 2017.10.31 Barcelona(Spain)

Nagaishi T, Watabe T, Jose N, Hosoya A, Kojima Y, Tsugawa N, Adachi T, Watanabe M. Deficiency of IgA Induces Microflora Alteration and Ileal Inflammation. ICMI 2017 2017.07.21 Washington DC (USA)

Hosoya A, Nagaishi T, Watabe T, Tsugawa N, Jose N, Kojima Y, Adachi T, Watanabe M. Verification of immunoglobulin A protection of intestinal mucosa from microflora. AOCC2017 2017.06.16 Seoul (Korea)

Nagaishi T, Watabe T, Jose N, Hosoya A, Kojima Y, Tsugawa N, Adachi T, Watanabe M. IgA Deficiency Induces Spontaneous Inflammation in the Ileum. FOCIS 2017 2017.06.14 Chicago (USA)

Watabe T, Nagaishi T, Hosoya A, Jose N, Tokai A, Kojima Y, Adachi T, Watanabe M. The lack of secreted IgA spontaneously induces the mucosal inflammation specifically in the ileum. DDW 2017 2017.05.09 Chicago (USA)

Kamei M, Chiba A, Nagaishi T, Haga K, Miyake S. MAIT cells exacerbate the disease course of oxazolone colitis.. 第45回日本免疫学会学術集会 2016.12.07 沖縄コンベンションセンター（沖縄県宜野湾市）

Watabe T, Nagaishi T, Tokai A, Jose N, Hosoya A, Kojima Y, Yamazaki M, Richard S. Blumberg, Watanabe M. CD66a regulation of BCR signaling in the activated B cells . APDW 2016 2016.11.04 神戸コンベンションセンター（兵庫県神戸市）

Watabe　T, Nagaishi T, Suzuki M, Yamazaki M, Onizawa M, Jose N, Tokai A, Hosoya A, Kojima Y, Watanabe M. Type 2 TNF receptor signaling in colonic epithelia may be involved in the development of colitis-associated carcinogenesis. APDW 2016 2016.11.03 神戸コンベンションセンター（兵庫県神戸市）

Hosoya A, Nagaishi T, Tokai A, Watabe T, Jose N, Kojima Y, Yamazaki M, Richard S. Blumberg, Watanabe M. CEACAM1 regulation of BCR signaling in the activated B cells. UEGW2016 2016.10.19 VIENNA

Nagaishi T, Tokai A, Watabe T, Jose N, Hosoya A, Yamazaki M, Blumberg RS, Watanabe M. BCR signaling in the activated B cells may be regulated by CEACAM1. Mucosal Immunology Course & Symposium (MICS）2016 2016.07.29 Toronto（Canada）

Taro Watabe, Takashi Nagaishi, Arisa Tokai, Akinori Hosoya, Nisha Jose, Yudai Kojima, Motomi Yamazaki, Richard S. Blumberg, Mamoru Watanabe. BCR signaling in the activated B cells may be regulated by CD66a. AOCC2016 2016.07.08 Kyoto International Conference Center, Kyoto（JAPAN）

Tokai A, Nagaishi T, Watabe T, Jose N, Hosoya A, Yamazaki M, Onizawa M, Richard S. Blumberg, Watanabe M . Activated B cell receptor signaling may be regulated by CEACAM1. FOCIS 2016 2016.06.23 Boston

Takashi Nagaishi, Arisa Tokai, Taro Watabe, Nisha Jose, Akinori Hosoya, Motomi Yamazaki, Richard S.Blumberg, Mamoru Watanabe. CEACAM1 may resulate BCR signaling in the activated B cells. DDW2016 2016.05.21 San Diego（USA）

Watabe T, Nagaishi T, Suzuki M, Yamazaki M, Onizawa M, Nisha J, Tokai A, Hosoya A, Kawai R, Watanabe M. APL may regulate chemokine production by macrophages in the setting of colitis. 第44回日本免疫学会学術集会 2015.11.20 札幌コンベンションセンター(北海道　札幌市）

Taro Watabe, Takashi Nagaishi, Masahiro Suzuki, Motomi Yamazaki, Michio Onizawa, Nisha Jose, Arisa Tokai, Akinori Hosoya, Risa Kawai, Mamoru Totsuka, Mamoru Watanabe. Epithelial TNFR2 signaling in the setting of ibd may be involved in the development of colitis-associated carcinogenesis . UEGW2015 2015.10.28 Barcelona

Taro Watabe, Takashi Nagaishi, Masahiro Suzuki, Motomi Yamazaki, Nisha Jose, Arisa Tokai, Akinori Hosoya, . Type 2 TNF receptor signaling in the epithelia may be involved　in the development of colitis-associated carcinogenesis. The 74th Annual Meeting of the Japanese Cancer Association 2015.10.08 Nagoya

Hosoya A,Nagaishi T,Watabe T,Suzuki M,Yamazaki M,Onizawa M,Nisha JOSE,Tokai A,Kawai L,Watanabe M. TNFR2 signaling in colonic epithelia may be involved in the development of colitis-associated carcinogenesis.. AOCC2015 2015.06.20 Beijing

Takashi Nagaishi, Taro Watabe, Masahiro Suzuki, Motomi Yamazaki, Nisha Jose, Arisa Tokai, Akinori Hosoya, Mamoru Watanabe. Epithelial NF-kB Activation via TNF Signaling May Be Involved in the Development of Colitis-Associated Carcinogenesis. DDW 2015 2015.05.18 Washington, D.C.

Jose N, Nagaishi T, Watabe T, Tokai A, Suzuki M, Yamazaki M, Watanabe M. The expression of myosin light chain kinase induced by NK-KB activation is involved in the development of colitis-associated cancer. UEGW2014 2014.10.22 Vienna