Yamane M, Ishikawa Y, Yamashita H, Morimoto K, Asano D, Sugawara T, Watanabe S, Ueda H, Akahoshi K, Ono H, Tanaka S, Tanabe M. Middle segment preserving pancreatectomy versus total pancreatectomy: a comparative analysis of short- and long-term outcomes. Surgery Today. 2024.12; Online ahead of print.

Hatano M, Akiyama Y, Shimada S, Yagi K, Akahoshi K, Itoh M, Tanabe M, Ogawa Y, Tanaka S. Loss of KDM6B epigenetically confers resistance to lipotoxicity in nonalcoholic fatty liver disease-related hepatocellular carcinoma. Hepatology Communications. 2023.10; 7 (10): e0277.

Yamane M, Ishikawa Y, Asano D, Watanabe S, Ueda H, Akahoshi K, Ono H, Kudo A, Tanaka S, Sugiyama Y, Muro S, Akita K, Tanabe M. Surgical anatomy of the dorsal pancreatic artery: Considering embryonic development. Pancreatology. 2023.09; 23 (6): 697-703. ( PubMed, DOI )

Murota Y, Nagane M, Wu M, Santra M, Venkateswaran S, Tanaka S, Bradley N, Taga T, Tabu K. A niche-mimicking polymer hydrogel-based approach to identify molecular targets for tackling human pancreatic cancer stem cells. Inflammation and Regeneration. 2023.09; 43 (1): 46. ( DOI )

Morimoto K, Ueda H, Asano D, Ishikawa Y, Watanabe S, Akahoshi K, Ono H, Kobayashi M, Okamoto R, Tanaka S, Tanabe M. Incidence and Mechanism of Refractory Postoperative Cholangitis After Hepatectomy with Hepaticojejunostomy. Journal of Gastrointestinal Surgery. 2023.06; 27 (8): 1668-1676.

Yagi K, Shimada S, Akiyama Y, Hatano M, Asano D, Ishikawa Y, Ueda H, Watanabe S, Akahoshi K, Ono H, Tanabe M, Tanaka S. Loss of SFXN1 mitigates lipotoxicity and predicts poor outcome in non-viral hepatocellular carcinoma. Sci Rep. 2023.06; 13 (1): 9449. ( PubMed, DOI )

Yamamoto Y, Shimada S, Akiyama Y, Tsukihara S, Sugimoto R, Kabashima A, Tokunaga M, Kinugasa Y, Kawakami Y, Tanaka S. RTP4 silencing provokes tumor-intrinsic resistance to immune checkpoint blockade in colorectal cancer. Journal of Gastroenterology. 2023.06; 58 (6): 540-553.

Yagi K, Ono H, Kudo A, Kinowaki Y, Asano D, Watanabe S, Ishikawa Y, Ueda H, Akahoshi K, Tanaka S, Tanabe M. MGMT is frequently inactivated in pancreatic NET-G2 and is associated with the therapeutic activity of STZ-based regimens. Sci Rep. 2023.05; 13 (1): 7535. ( PubMed, DOI )

Ono H, Murase Y, Yamashita H, Kato T, Asano D, Ishikawa Y, Watanabe S, Ueda H, Akahoshi K, Ogawa K, Kudo A, Akiyama Y, Tanaka S, Tanabe M. RRM1 is mediated by histone acetylation through gemcitabine resistance and contributes to invasiveness and ECM remodeling in pancreatic cancer. International Journal of Oncology. 2023.04; 62 (4): 51.

Ishii T, Akiyama Y, Shimada S, Kabashima A, Asano D, Watanabe S, Ishikawa Y, Ueda H, Akahoshi K, Ogawa K, Ono H, Kudo A, Tanabe M, Tanaka S. Identification of a novel target of SETD1A histone methyltransferase and the clinical significance in pancreatic cancer. Cancer Science. 2023.02; 114 (2): 463-476.

Shimada S, Tanaka S. The chronicles of hepatocellular carcinoma classification: subtyping, modeling and treatment. Hepatology. 2023; in press.

Ichihara M, Takahashi H, Nishida N, Ivan C, Okuzaki D, Yokoyama Y, Ohtsuka M, Miyoshi N, Uemura M, Tanaka S, Calin G, Mori M, Doki Y, Eguchi, H, Yamamoto H. Long noncoding RNA 01534 maintains cancer stemness by down-regulating endoplasmic reticulum stress response in colorectal cancer Annals of Gastroenterological Surgery. 2022.12; 7 (3): 458-470. ( PubMed )

Ichihara M, Takahashi H, Nishida N, Ivan C, Okuzaki D, Yokoyama Y, Ohtsuka M, Miyoshi N, Uemura M, Tanaka S, Calin G, Mori M, Doki Y, Eguchi, H, Yamamoto H. Long noncoding RNA 01534 maintains cancer stemness by down-regulating endoplasmic reticulum stress response in colorectal cancer Annals of Gastroenterological Surgery. 2022.12; 7 (3): 458-470.

Ishii Takeshi, Akiyama Yoshimitsu, Shimada Shu, Kabashima Ayano, Asano Daisuke, Watanabe Shuichi, Ishikawa Yoshiya, Ueda Hiroki, Akahoshi Keiichi, Ogawa Kosuke, Ono Hiroaki, Kudo Atsushi, Tanabe Minoru, Tanaka Shinji. Identification of a novel target of SETD1A histone methyltransferase and the clinical significance in pancreatic cancer CANCER SCIENCE. 2022.11; 114 (2): 463-476.

Asano D, Kudo A, Akahoshi K, Maekawa A, Murase Y, Ogawa K, Ono H, Ban D, Tanaka S, Tanabe M. Curative Surgery and Ki-67 Value Rather than Tumor Differentiation Predict the Survival of Patients with High-grade Neuroendocrine Neoplasms. Annals of Surgery. 2022.08; 276 (2): e108-e113.

Shimada S, Tanaka S. Molecular targeted drugs, comprehensive classification and preclinical models for the implementation of precision immune oncology in hepatocellular carcinoma International Journal of Clinical Oncology. 2022.07; 27 (7): 1101-1109. ( PubMed, DOI )

Kabashima A, Matsuo Y, Ito S, Akiyama Y, Ishii T, Shimada S, Masamune A, Tanabe M, Tanaka S. cGAS-STING signaling encourages immune cell overcoming of fibroblast barricades in pancreatic cancer. Scientific reports. 2022.06; 12 (1): 10466. ( PubMed, DOI )

Kato T, Kudo A, Kinowaki Y, Ishikawa Y, Watanabe S, Akahoshi K, Ogawa K, Ono H, Ban D, Tanaka S, Tanabe M. A novel classification of portal venous tumor invasion to predict residual tumor status after surgery in patients with pancreatic neuroendocrine neoplasms. J Cancer Res Clin Oncol. 2022.04; 148 (4): 931-941. ( PubMed, DOI )

Maekawa A, Kudo A, Kishino Mitsuhiro, Murase Y, Watanabe S, Ishikawa Y, Ueda Hiroki, Akahoshi K, Ogawa K, Ono H, Tanaka S, Kinowaki Y, Tanabe M.. Hormonal tumor mapping for liver metastases of gastroenteropancreatic neuroendocrine neoplasms: a novel therapeutic strategy. Journal of Cancer Research and Clinical Oncology. 2022.03; 148 (3): 697-706. ( DOI )

Wang J, Hirose H, Yokoyama Y, Ikeshima R, Tsujimura N, Bonkobara S, Takeda K, Hata T, Inoue A, Hiraki M, Ohtsuka M, Nishida N, Takahashi H, Haraguchi N, Tanaka S, Wu X, Mori M, Yamamoto H.. Functional assessment of miR-1291 in colon cancer cells. International Journal of Oncology. 2022.02; 60 (2): 13. ( PubMed, DOI )

Zhang M, Sugita I, Komura D, Katoh H, Shimada S, Inazawa J, Tanaka S, Ishikawa S. Genomic landscape of a mouse model of diffuse-type gastric adenocarcinoma Gastric Cancer. 2022.01; 25 (1): 83-95. ( PubMed )

Ishii T, Akiyama Y, Shimada S, Kabashima A, Asano D, Watanabe S, Ishikawa Y, Ueda H, Akahoshi K, Ogawa K, Ono H, Kudo A, Tanabe M, Tanaka S. Identification of a novel target of SETD1A histone methyltransferase and the clinical significance in pancreatic cancer Cancer Science. 2022;

Yamamoto Y, Shimada S, Akiyama Y, Tsukihara S, Sugimoto R, Kabashima A, Tokunaga M, Kinugasa Y, Kawakami Y, Tanaka S. RTP4 silencing provokes tumor-intrinsic resistance to immune checkpoint blockade in colorectal cancer. Journal of Gastroenterology. 2022;

Ichihara M, Takahashi H, Nishida N, Ivan C, Okuzaki D, Yokoyama Y, Ohtsuka M, Miyoshi N, Uemura M, Tanaka S, Calin G, Mori M, Doki Y, Eguchi, H, Yamamoto H. Long noncoding RNA 01534 maintains cancer stemness by down-regulating endoplasmic reticulum stress response in colorectal cancer. Annals of Gastroenterological Surgery. 2022; 7 (3): 458-470. ( PubMed, DOI )

Murase Yoshiki, Ono Hiroaki, Ogawa Kosuke, Yoshioka Risa, Ishikawa Yoshiya, Ueda Hiroki, Akahoshi Keiichi, Ban Daisuke, Kudo Atsushi, Tanaka Shinji, Tanabe Minoru. Inhibitor library screening identifies ispinesib as a new potential chemotherapeutic agent for pancreatic cancers(和訳中) Cancer Science. 2021.11; 112 (11): 4641-4654. ( ichushi )

Taniai Tomohiko, Shirai Yoshihiro, Shimada Yohta, Hamura Ryoga, Yanagaki Mitsuru, Takada Naoki, Horiuchi Takashi, Haruki Koichiro, Furukawa Kenei, Uwagawa Tadashi, Tsuboi Kazuhito, Okamoto Yasuo, Shimada Shu, Tanaka Shinji, Ohashi Toya, Ikegami Toru. Inhibition of acid ceramidase elicits mitochondrial dysfunction and oxidative stress in pancreatic cancer cells(和訳中) Cancer Science. 2021.11; 112 (11): 4570-4579. ( ichushi )

Yoshiki Murase, Hiroaki Ono, Kosuke Ogawa, Risa Yoshioka, Yoshiya Ishikawa, Hiroki Ueda, Keiichi Akahoshi, Daisuke Ban, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Inhibitor library screening identifies ispinesib as a new potential chemotherapeutic agent for pancreatic cancers Cancer Science. 2021.09; Early View (11): 4641-4654. ( PubMed, DOI )

Zhang M, Sugita I, Komura D, Katoh H, Shimada S, Inazawa J, Tanaka S, Ishikawa S. Genomic landscape of a mouse model of diffuse-type gastric adenocarcinoma. Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association. 2021.08; ( PubMed, DOI )

Satoshi Matsui, Hiroaki Ono, Daisuke Asano, Yoshiya Ishikawa, Hiroki Ueda, Keiichi Akahoshi, Kosuke Ogawa, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Pancreatic metastasis from renal cell carcinoma presenting as gastrointestinal hemorrhage: a case report Jornal of Surgical Case Reports. 2021.08; 2021 (8): rjab368.

Masafumi Akasu, Shu Shimada, Ayano Kabashima, Yoshimitsu Akiyama, Masahiro Shimokawa, Keiichi Akahoshi, Atsushi Kudo, Shoji Yamaoka, Minoru Tanabe, Shinji Tanaka. Intrinsic activation of β-catenin signaling by CRISPR/Cas9-mediated exon skipping contributes to immune evasion in hepatocellular carcinoma Scientific Reports. 2021.08; 11 (1): 16732.

Matsui S, Ono H, Asano D, Ishikawa Y, Ueda H, Akahoshi K, Ogawa K, Kudo A, Tanaka S, Tanabe M. Pancreatic metastasis from renal cell carcinoma presenting as gastrointestinal hemorrhage: a case report. Journal of surgical case reports. 2021.08; 2021 (8): rjab368. ( PubMed, DOI )

Tomotaka Kato,Hiroaki Ono, Mikiya Fujii, Keiichi Akahoshi, Toshiro Ogura, Kosuke Ogawa, Daisuke Ban, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Cytoplasmic RRM1 activation as an acute response to gemcitabine treatment is involved in drug resistance of pancreatic cancer cells. PLoS One. 2021.06; 16 (6): e0252917.

Hiroyuki Ishida, Yoshiya Ishikawa, Keiichi Akahoshi, Hiroki Ueda, Koichiro Morimoto, Hironari Yamashita, Kosuke Ogawa, Hiroaki Ono, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe.. Laparoscopic distal pancreatectomy in a patient with aberrant splenic artery originating from the superior mesenteric artery: A case report 2021.05; 100 (18): e25704.

Hiroaki Ono, Tomotaka Kato, Yoshiki Murase, Yutaro Nakamura, Yoshiya Ishikawa, Shuichi Watanabe, Keiichi Akahoshi, Toshiro Ogura, Kosuke Ogawa, Daisuke Ban, Atsushi Kudo, Yoshimitsu Akiyama, Shinji Tanaka, Hiromichi Ito, Minoru Tanabe. . C646 inhibits G2/M cell cycle-related proteins and potentiates anti-tumor effects in pancreatic cancer Scientific Reports. 2021.05; 11 (1): 10078.

Fukuda Tatsuya, Bouchi Ryotaro, Takeuchi Takato, Amo-Shiinoki Kikuko, Kudo Atsushi, Tanaka Shinji, Tanabe Minoru, Akashi Takumi, Hirayama Kazuhiro, Odamaki Toshitaka, Igarashi Miki, Kimura Ikuo, Tanabe Katsuya, Tanizawa Yukio, Yamada Tetsuya, Ogawa Yoshihiro. Importance of Intestinal Environment and Cellular Plasticity of Islets in the Development of Postpancreatectomy Diabetes DIABETES CARE. 2021.04; 44 (4): 1002-1011. ( PubMed, DOI )

Tatsuya Fukuda, Ryotaro Bouchi, Takato Takeuchi, Kikuko Amo-Shiinoki, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe, Takumi Akashi, Kazuhiro Hirayama, Toshitaka Odamaki, Miki Igarashi, Ikuo Kimura, Katsuya Tanabe, Yukio Tanizawa, Tetsuya Yamada and Yoshihiro Ogawa. Importance of Intestinal Environment and Cellular Plasticity of Islets in the Development of Postpancreatectomy Diabetes Diabetes Care. 2021.04; 44 (4): 1002-1011.

Maekawa A, Kudo A, Kishino M, Murase Y, Watanabe S, Ishikawa Y, Ueda H, Akahoshi K, Ogawa K, Ono H, Tanaka S, Kinowaki Y, Tanabe M.. Hormonal tumor mapping for liver metastases of gastroenteropancreatic neuroendocrine neoplasms: a novel therapeutic strategy Journal of Cancer Research and Clinical Oncology. 2021.04; published online

Toshitaka Sugawara, Daisuke Ban, Jo Nishino, Shuichi Watanabe, Aya Maekawa, Yoshiya Ishikawa, Keiichi Akahoshi, Kosuke Ogawa, Hiroaki Ono, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Prediction of early recurrence of pancreatic ductal adenocarcinoma after resection PLoS One. 2021.04; 16 (4): e0249885.

Yoshiki Murase, Atsushi Kudo, Keiichi Akahoshi, Aya Maekawa, Yoshiya Ishikawa, Hiroki Ueda, Kosuke Ogawa, Hiroaki Ono, Shinji Tanaka, Minoru Tanabe. Surgery after sunitinib administration to improve survival of patients with advanced pancreatic neuroendocrine neoplasms Annals of Gastroenterological Surgery. 2021.03; 0 (0): 1-9.

Yasuhito Iwao, Daisuke Ban, Satoru Muro, Atsushi Kudo, Shinji Tanaka, Krishna Menon, Minoru Tanabe. Extraordinary first jejunal arterial variation associated with annular pancreas undergoing pancreaticoduodenectomy for pancreatic cancer: a case report Surgical and Radiologic Anatomy. 2021.01;

Kikuko Amo-Shiinoki, Katsuya Tanabe, Yoshinobu Hoshii, Hiroto Matsui, Risa Harano, Tatsuya Fukuda, Takato Takeuchi, Ryotaro Bouchi, Tokiyo Takagi, Masayuki Hatanaka, Komei Takeda, Shigeru Okuya, Wataru Nishimura, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe, Takumi Akashi, Tetsuya Yamada, Yoshihiro Ogawa, Eiji Ikeda, Hiroaki Nagano, and Yukio Tanizawa. Islet cell dedifferentiation is a pathologic mechanism of long-standing progression of type 2 diabetes JCI insight. 2021.01; 6 (1): e143791.

Kabashima Ayano, Shimada Shu, Shimokawa Masahiro, Akiyama Yoshimitsu, Tanabe Minoru, Tanaka Shinji. Molecular and immunological paradigms of hepatocellular carcinoma: Special reference to therapeutic approaches Journal of Hepato-Biliary-Pancreatic Sciences . 2021.01; 28 (1): 62-75. ( PubMed, DOI )

Yoshiki Murase, Daisuke Ban, Aya Maekawa, Shuichi Watanabe, Yoshiya Ishikawa, Keiichi Akahoshi, Kosuke Ogawa, Hiroaki Ono, Atsushi Kudo, Toshifumi Kudo, Shinji Tanaka, Minoru Tanabe. Successful conversion　surgery　of　distal　pancreatectomy　with　celiac　axis　resection(DP-CAR)　with　double　arterial　reconstruction using saphenous vein grafting for locally advanced pancreatic cancer: a case report Surgical Case Reports. 2020.12;

Murase Y, Ban D, Maekawa A, Watanabe S, Ishikawa Y, Akahoshi K, Ogawa K, Ono H, Kudo A, Kudo T, Tanaka S, Tanabe M. Successful conversion surgery of distal pancreatectomy with celiac axis resection (DP-CAR) with double arterial reconstruction using saphenous vein grafting for locally advanced pancreatic cancer: a case report. Surgical case reports. 2020.12; 6 (1): 302. ( PubMed, DOI )

Kimura Koichiro, Tsuchiya Junichi, Kitazume Yoshio, Kishino Mitsuhiro, Akahoshi Keiichi, Kudo Atsushi, Tanaka Shinji, Tanabe Minoru, Tateishi Ukihide. Dynamic Enhancement Pattern on CT for Predicting Pancreatic Neuroendocrine Neoplasms with Low PAX6 Expression: A Retrospective Observational Study DIAGNOSTICS. 2020.11; 10 (11): ( PubMed, DOI )

Koichiro Kimura, Junichi Tsuchiya, Yoshio Kitazume, Mitsuhiro Kishino, Keiichi Akahoshi, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe, Ukihide Tateishi . Dynamic Enhancement Pattern on CT for Predicting Pancreatic Neuroendocrine Neoplasms with Low PAX6 Expression: A Retrospective Observational Study Diagnostics . 2020.11; 10 (11): 919.

島田 周, 秋山 好光, 田邉 稔, 田中 真二. KDM6A発現低下を特徴とする膵がん予後不良サブタイプにはHDAC阻害剤が著効する 日本癌学会総会記事. 2020.10; 79回 OJ14-6. ( ichushi )

Asano D, Kudo A, Akahoshi K, Maekawa A, Murase Y, Ogawa K, Ono H, Ban D, Tanaka S, Tanabe M. Curative Surgery and Ki-67 Value Rather than Tumor Differentiation Predict the Survival of Patients with High-grade Neuroendocrine Neoplasms. Annals of surgery. 2020.09; ( PubMed, DOI )

Asano, Daisuke, Kudo, Atsushi, Akahoshi, Keiichi, Maekawa, Aya, Murase, Yoshiki, Ogawa, Kosuke, Ono, Hiroaki, Ban, Daisuke, Tanaka, Shinji, Tanabe, Minoru . Curative Surgery and Ki-67 Value Rather than Tumor Differentiation Predict the Survival of Patients with High-grade Neuroendocrine Neoplasms Annals of Surgery . 2020.09;

Kudo Atsushi, Akahoshi Keiichi, Ito Sakiko, Akashi Takumi, Shimada Shu, Ogura Toshiro, Ogawa Kosuke, Ono Hiroaki, Mitsunori Yusuke, Ban Daisuke, Tateishi Ukihide, Tanaka Shinji, Tanabe Minoru. Downregulated Pancreatic Beta Cell Genes Indicate Poor Prognosis in Patients With Pancreatic Neuroendocrine Neoplasms ANNALS OF SURGERY. 2020.04; 271 (4): 732-739. ( PubMed, DOI )

Hiroaki Ono, Atsushi Kudo, Keiichi Akahoshi, Toshiro Ogura, Kosuke Ogawa, Daisuke Ban, Shinji Tanaka, Minoru Tanabe. Combination of weekly streptozocin and oral S-1 treatment for patients of unresectable or metastatic pancreatic neuroendocrine neoplasms Journal of Cancer Research and Clinical Oncology. 2020.03; 146 (3): 793-799.

Fujita Masashi, Yamaguchi Rui, Hasegawa Takanori, Shimada Shu, Arihiro Koji, Hayashi Shuto, Maejima Kazuhiro, Nakano Kaoru, Fujimoto Akihiro, Ono Atsushi, Aikata Hiroshi, Ueno Masaki, Hayami Shinya, Tanaka Hiroko, Miyano Satoru, Yamaue Hiroki, Chayama Kazuaki, Kakimi Kazuhiro, Tanaka Shinji, Imoto Seiya, Nakagawa Hidewaki. Classification of primary liver cancer with immunosuppression mechanisms and correlation with genomic alterations EBIOMEDICINE. 2020.03; 53 102659. ( PubMed, DOI )

Ono Hiroaki, Kudo Atsushi, Akahoshi Keiichi, Ogura Toshiro, Ogawa Kosuke, Ban Daisuke, Tanaka Shinji, Tanabe Minoru. Combination of weekly streptozocin and oral S-1 treatment for patients of unresectable or metastatic pancreatic neuroendocrine neoplasms JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY. 2020.03; 146 (3): 793-799. ( PubMed, DOI )

Ono S, Dohi O, Yagi N, Sanomura Y, Tanaka S, Naito Y, Sakamoto N, Kato M. Accuracies of Endoscopic Diagnosis of Helicobacter pylori-Gastritis: Multicenter Prospective Study Using White Light Imaging and Linked Color Imaging. Digestion. 2020; 101 (5): 624-630. ( PubMed, DOI )

Matsui S, Ogura T, Ban D, Ogawa K, Ono H, Mitsunori Y, Kudo A, Tanaka S, Tanabe M.. Position of the Pancreas Division Line and Postoperative Outcomes After Distal Pancreatectomy. World Journal of Surgery. 2019.11;

Qian Yamin, Wu Xin, Yokoyama Yuhki, Okuzaki Daisuke, Taguchi Mai, Hirose Haruka, Wang Jiaqi, Hata Tsuyoshi, Inoue Akira, Hiraki Masayuki, Ohtsuka Masahisa, Takahashi Hidekazu, Haraguchi Naotsugu, Mizushima Tsunekazu, Tanaka Shinji, Mori Masaki, Yamamoto Hirofumi. E-cadherin-Fc chimera protein matrix enhances cancer stem-like properties and induces mesenchymal features in colon cancer cells CANCER SCIENCE. 2019.11; 110 (11): 3520-3532. ( PubMed, DOI )

Ono Hiroaki, Ikeda Sadakatsu, Ogawa Kosuke, Ogura Toshiro, Ban Daisuke, Kudo Atushi, Miyake Satoshi, Tanaka Shinji, Tanabe Minoru. HBP悪性腫瘍のゲノムシーケンス解析(Genomic sequencing in HBP malignancies) 日本消化器病学会雑誌. 2019.11; 116 (臨増大会): A893. ( ichushi )

Qian Yamin, Wu Xin, Yokoyama Yuhki, Okuzaki Daisuke, Taguchi Mai, Hirose Haruka, Wang Jiaqi, Hata Tsuyoshi, Inoue Akira, Hiraki Masayuki, Ohtsuka Masahisa, Takahashi Hidekazu, Haraguchi Naotsugu, Mizushima Tsunekazu, Tanaka Shinji, Mori Masaki, Yamamoto Hirofumi. E-カドヘリン-Fcキメラ蛋白質マトリックスは、癌幹細胞の特性を増強し、結腸癌細胞の間葉系特性を誘導する(E-cadherin-Fc chimera protein matrix enhances cancer stem-like properties and induces mesenchymal features in colon cancer cells) Cancer Science. 2019.11; 110 (11): 3520-3532. ( ichushi )

Ono Hiroaki, Ikeda Sadakatsu, Ogawa Kosuke, Ogura Toshiro, Ban Daisuke, Kudo Atushi, Miyake Satoshi, Tanaka Shinji, Tanabe Minoru. HBP悪性疾患に関するゲノムシークエンス解析(Genomic sequencing in HBP malignancies) 日本消化器外科学会雑誌. 2019.11; 52 (Suppl.2): 306. ( ichushi )

Yoshino J, Akiyama Y, Shimada S, Ogura T, Ogawa K, Ono H, Mitsunori Y, Ban D, Kudo A, Yamaoka S, Tanabe M, Tanaka S.. Loss of ARID1A induces a stemness gene ALDH1A1 expression with histone acetylation in the malignant subtype of cholangiocarcinoma. Carcinogenesis. 2019.10;

Bo Liu, Atsushi Kudo, Yuko Kinowaki, Toshiro Ogura, Kosuke Ogawa, Hiroaki Ono, Yusuke Mitsunori, Daisuke Ban, Shinji Tanaka, Takumi Akashi, Minoru Tanabe. A simple and practical index predicting the prognoses of the patients with well-differentiated pancreatic neuroendocrine neoplasms The Japanese Society of Gastroenterology. 2019.09; 54 (9): 819-828.

Liu Bo, Kudo Atsushi, Kinowaki Yuko, Ogura Toshiro, Ogawa Kosuke, Ono Hiroaki, Mitsunori Yusuke, Ban Daisuke, Tanaka Shinji, Akashi Takumi, Tanabe Minoru. A simple and practical index predicting the prognoses of the patients with well-differentiated pancreatic neuroendocrine neoplasms JOURNAL OF GASTROENTEROLOGY. 2019.09; 54 (9): 819-828. ( PubMed, DOI )

Jun Yoshino, Daisuke Ban, Toshiro Ogura, Kosuke Ogawa, Hiroaki Ono, Yusuke Mitsunori, Atsushi Kudo, Shinji Tanaka & Minoru Tanabe. The Clinial Implications of Peripancreatic Fluid Collection After Distal Pancreatectomy World Journal of Surgery. 2019.08; 43 (8): 2069-2076.

Matsui S, Kudo A, Ogura T, Ogawa K, Ono H, Mitsunori Y, Ban D, Tanaka S, Tanabe M.. Does sunitinib have a patient-specific dose without diminishing its antitumor effect on advanced pancreatic neuroendocrine neoplasms? Journal of Cancer Research and Clinical Oncology. 2019.08; 145 (8): 2097-2104.

Matsui Satoshi, Kudo Atsushi, Ogura Toshiro, Ogawa Kosuke, Ono Hiroaki, Mitsunori Yusuke, Ban Daisuke, Tanaka Shinji, Tanabe Minoru. Does sunitinib have a patient-specific dose without diminishing its antitumor effect on advanced pancreatic neuroendocrine neoplasms? JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY. 2019.08; 145 (8): 2097-2104. ( PubMed, DOI )

Shimada Shu, Tanaka Shinji. A new era for understanding genetic evolution of multistep carcinogenesis JOURNAL OF GASTROENTEROLOGY. 2019.07; 54 (7): 667-668. ( PubMed, DOI )

Watanabe Shuichi, Shimada Shu, Akiyama Yoshimitsu, Ishikawa Yoshiya, Ogura Toshiro, Ogawa Kosuke, Ono Hiroaki, Mitsunori Yusuke, Ban Daisuke, Kudo Atsushi, Yamaoka Shoji, Tanabe Minoru, Tanaka Shinji. Loss of KDM6A characterizes a poor prognostic subtype of human pancreatic cancer and potentiates HDAC inhibitor lethality INTERNATIONAL JOURNAL OF CANCER. 2019.07; 145 (1): 192-205. ( PubMed, DOI )

Shimada Shu, Tanaka Shinji. 多段階発癌の遺伝的進化の理解の新時代(A new era for understanding genetic evolution of multistep carcinogenesis) Journal of Gastroenterology. 2019.07; 54 (7): 667-668. ( ichushi )

Ban Daisuke, Kudo Atsushi, Tanaka Shinji, Tanabe Minoru. HBP外科専門医への教育ロードマップ　腹腔鏡下HBP外科専門医へのロードマップ(Education roadmap to qualified HBP surgeons　Roadmap to the qualified laparoscopic HBP surgeon) 日本肝胆膵外科学会・学術集会プログラム・抄録集. 2019.06; 31回 ESY1-1. ( ichushi )

Fukamachi Hiroshi, Kim Seon-Kyu, Koh Jiwon, Lee Hye Seung, Sasaki Yasushi, Yamashita Kentaro, Nishikawaji Taketo, Shimada Shu, Akiyama Yoshimitsu, Byeon Sun-ju, Bae Dong-Hyuck, Okuno Keisuke, Nakagawa Masatoshi, Tanioka Toshiro, Inokuchi Mikito, Kawachi Hiroshi, Tsuchiya Kiichiro, Kojima Kazuyuki, Tokino Takashi, Eishi Yoshinobu, Kim Yong Sung, Kim Woo Ho, Yuasa Yasuhito, Tanaka Shinji. A subset of diffuse-type gastric cancer is susceptible to mTOR inhibitors and checkpoint inhibitors JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH. 2019.03; 38 (1): 127. ( PubMed, DOI )

Shimada Shu, Mogushi Kaoru, Akiyama Yoshimitsu, Furuyama Takaki, Watanabe Shuichi, Ogura Toshiro, Ogawa Kosuke, Ono Hiroaki, Mitsunori Yusuke, Ban Daisuke, Kudo Atsushi, Arii Shigeki, Tanabe Minoru, Wands Jack R., Tanaka Shinji. Comprehensive molecular and immunological characterization of hepatocellular carcinoma EBIOMEDICINE. 2019.02; 40 457-470. ( PubMed, DOI )

Okuno Keisuke, Akiyama Yoshimitsu, Shimada Shu, Nakagawa Masatoshi, Tanioka Toshiro, Inokuchi Mikito, Yamaoka Shoji, Kojima Kazuyuki, Tanaka Shinji. Asymmetric dimethylation at histone H3 arginine 2 by PRMT6 in gastric cancer progression CARCINOGENESIS. 2019.01; 40 (1): 15-26. ( PubMed, DOI )

Ishikawa Y, Ban D, Watanabe S, Akahoshi K, Ono H, Mitsunori Y, Kudo A, Tanaka S, Tanabe M. Splenic artery as a simple landmark indicating difficulty during laparoscopic distal pancreatectomy. Asian journal of endoscopic surgery. 2019.01; 12 (1): 81-87. ( PubMed, DOI )

Watanabe Yuichiro, Honda Shinya, Konishi Akimitsu, Tanabe Minoru, Tanaka Shinji, Shimizu Shigeomi. Autophagy controls centrosome number by degrading Cep63 CANCER SCIENCE. 2018.12; 109 309.

Shimada Shu, Akiyama Yoshimitsu, Tanabe Minoru, Tanaka Shinji. FABP4 overexpression in intratumoral hepatic stellate cells within hepatocellular carcinoma with metabolic risk factors CANCER SCIENCE. 2018.12; 109 940.

Fukamachi Hiroshi, Nishikawaji Taketo, Shimada Shu, Akiyama Yoshimitsu, Yuasa Yasuhito, Tsuchiya Kiichiro, Tanaka Shinji. Diffuse-type gastric cancers are classified into two clusters, which may be formed via different carcinogenic pathways CANCER SCIENCE. 2018.12; 109 1131.

Mizuno Yuki, Shimada Shu, Akiyama Yoshimitsu, Watanabe Shuichi, Aida Tomomi, Ogawa Kosuske, Ono Hiroaki, Mitsunori Yusuke, Ban Daisuke, Kudo Atsushi, Yamaoka Shoji, Tanaka Shinji, Tanabe Minoru. DEPDC5 deficiency contributes to resistance to leucine starvation via p62 accumulation in hepatocellular carcinoma CANCER SCIENCE. 2018.12; 109 952.

Akiyama Yoshimitsu, Shimada Shu, Tanabe Minoru, Tanaka Shinji. DAXX acts as a tumor suppressor through histone H3.3/H3K9me3 pathway in pancreatic neuroendocrine tumors CANCER SCIENCE. 2018.12; 109 1103.

Tanaka Shinji. Molecular target therapy for liver cancer under precision medicine CANCER SCIENCE. 2018.12; 109 634.

Keiichi Akahoshi, Hiroaki Ono, Masafumi Akasu, Daisuke Ban, Atsushi Kudo, Atsuko Konta, Shinji Tanaka, Minoru Tanabe. Rapid growth speed of cysts can predict malignant intraductal mucinous papillary neoplasms Journal of Surgical Research. 2018.11; 231 195-200.

Keiichi Akahoshi、Daisuke Ban, Ryo Kuboki, Atsushi Oba, Hiroaki Ono, Yusuke Mitsunori, Atsushi Kudo, Shinji Tanaka and Minoru Tanabe. Orotate phosphoribosyltransferase as a predictor of benefit from S-1 adjuvant chemotherapy for cholangiocarcinoma patients Journal of Gastroenterology and Hepatology. 2018.09;

Kudo A, Akahoshi K, Ito S, Akashi T, Shimada S, Ogura T, Ogawa K, Ono H, Mitsunori Y, Ban D, Tateishi U, Tanaka S, Tanabe M.. Downregulated Pancreatic Beta Cell Genes Indicate Poor Prognosis in Patients With Pancreatic Neuroendocrine Neoplasms. Ann Surg.. 2018.07;

Ueda H, Akiyama Y, Shimada S, Mogushi K, Serizawa M, Matsumura S, Mitsunori Y, Aihara A, Ban D, Ochiai T, Kudo A, Tanabe M, Tanaka S.. Tumor suppressor functions of DAXX through histone H3.3/H3K9me3 pathway in pancreatic NETs. Endocr Relat Cancer. 2018.06; 25 (6): 619-631.

松井　聡、伴　大輔、工藤　篤、田中真二、田邉　稔. 減量切除が有用であった血糖制御不能な悪性インスリノーマの1例 臨床外科. 2018.05; 79 (5): 138-144.

Norimichi Chiyonobu, Shu Shimada, Yoshimitsu Akiyama, Kaoru Mogushi, Michiko Itoh, Keiichi Akahoshi, Satoshi Matsumura, Kosuke Ogawa, Hiroaki Ono, Yusuke Mitsunori, Daisuke Ban, Atsushi Kudo, Shigeki Arii, Takayoshi Suganami, Shoji Yamaoka, Yoshihiro Ogawa, Minoru Tanabe, Shinji Tanaka. Fatty acid binding protein 4 (FABP4) overexpression in intratumoral hepatic stellate cells within hepatocellular carcinoma with metabolic risk factors The American Journal of Pathology. 2018.05; 188 (5):

Chiyonobu Norimichi, Shimada Shu, Akiyama Yoshimitsu, Mogushi Kaoru, Itoh Michiko, Akahoshi Keiichi, Matsumura Satoshi, Ogawa Kosuke, Ono Hiroaki, Mitsunori Yusuke, Ban Daisuke, Kudo Atsushi, Arii Shigeki, Suganami Takayoshi, Yamaoka Shoji, Ogawa Yoshihiro, Tanabe Minoru, Tanaka Shinji. Fatty Acid Binding Protein 4 (FABP4) Overexpression in Intratumoral Hepatic Stellate Cells within Hepatocellular Carcinoma with Metabolic Risk Factors AMERICAN JOURNAL OF PATHOLOGY. 2018.05; 188 (5): 1213-1224. ( PubMed, DOI )

Kawai-Kitahata F., Asahina Y., Kakinuma S., Murakawa M., Nitta S., Nagata H., Kaneko S., Inoue E., Miyoshi M., Tsunoda T., Sato A., Nakagawa M., Itsui Y., Azuma S., Tanaka S., Tanabe M., Maekawa S., Enomoto N., Watanabe M.. Difference of gene mutational profile among viral- and non-viral HCC with or without prior HBV infection: Results of comprehensive deep sequencing analyses of cancer genes and HBV/AAV integration JOURNAL OF HEPATOLOGY. 2018.04; 68 S667.

Shimada Shu, Akiyama Yoshimitsu, Mogushi Kaoru, Ishigami-Yuasa Mari, Kagechika Hiroyuki, Nagasaki Hiromi, Fukamachi Hiroshi, Yuasa Yasuhito, Tanaka Shinji. Identification of selective inhibitors for diffuse-type gastric cancer cells by screening of annotated compounds in preclinical models BRITISH JOURNAL OF CANCER. 2018.04; 118 (7): 972-984. ( PubMed, DOI )

Yuki Mizuno,Atsushi Kudo,Takumi Akashi,Toshiro Ogura,Kosuke Ogawa,Hiroaki Ono, Yusuke Mitsunori,Daisuke Ban, Shinji Tanaka, Ukihide Tateishi, Minoru Tanabe. Sunitinib shrinks NET-G3 pancreatic neuroendocrine neoplasms Journal of Cancer Research and Clinical Oncology. 2018.03; 144 1155-1163.

Tanaka Shinji. HCCと膵癌に対するオーダーメイド医療(Precision medicine for HCC and pancreatic cancer) 日本消化器病学会雑誌. 2018.03; 115 (臨増総会): A200. ( ichushi )

Tanaka Shinji. ゲノム規模解析およびゲノム編集技術の時代に外科腫瘍学に基づいた精密医療(Precision medicine based on surgical oncology in the era of genome-scale analysis and genome editing technology) Annals of Gastroenterological Surgery. 2018.03; 2 (2): 106-115. ( ichushi )

Yoshiya Ishikawa, Daisuke Ban, Shuichi Watanabe, Keiichi Akahoshi, Hiroaki Ono, Yusuke Mitsunori, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Splenic artery as a simple landmark indicating difficulty during laparoscopic distal pancreatectomy Asian Journal of Endscopic Surgery. 2018.02; 1-7.

Mizuno Y, Shimada S, Akiyama Y, Watanabe S, Aida T, Ogawa K, Ono H, Mitsunori Y, Ban D, Kudo A, Arii S, Yamaoka S, Tanabe M, Tanaka S.. DEPDC5 deficiency contributes to resistance to leucine starvation via p62 accumulation in hepatocellular carcinoma. Sci Rep. . 2018.01; 8 (1):

Shimada Shu, Akiyama Yoshimitsu, Tanaka Shinji. Acquired resistance with epigenetic alterations under long-term anti-angiogenic therapy for hepatocellular carcinoma CANCER SCIENCE. 2018.01; 109 60.

Fukamachi Hiroshi, Nishikawaji Taketo, Shimada Shu, Akiyama Yoshimitsu, Yuasa Yasuhito, Tuchiya Kiichiro, Tanaka Shinji. Identification of signal transduction pathway in PDX-derived diffuse-type gastric tumor-initiating cells CANCER SCIENCE. 2018.01; 109 880.

Mizuno Yuki, Shimada Shu, Akiyama Yoshimitsu, Watanabe Shuichi, Aida Tomomi, Ogawa Kosuke, Ono Hiroaki, Mitsunori Yusuke, Ban Daisuke, Kudo Atsushi, Arii Shigeki, Yamaoka Shoji, Tanabe Minoru, Tanaka Shinji. DEPDC5 deficiency contributes to resistance to leucine starvation via p62 accumulation in hepatocellular carcinoma SCIENTIFIC REPORTS. 2018.01; 8 (1): 106. ( PubMed, DOI )

Akiyama Yoshimitsu, Nishikawaji Taketo, Shimada Shu, Yuasa Yasuhito, Tanaka Shinji. Molecular mechanisms of SETDB2 histone methyltransferase overexpression in gastric cancer CANCER SCIENCE. 2018.01; 109 913.

Oba Atsushi, Ban Daisuke, Kudo Atsushi, Kirimura Susumu, Ito Hiromitsu, Matsumura Satoshi, Mitsunori Yusuke, Aihara Arihiro, Ochiai Takanori, Tanaka Shinji, Tanabe Minoru. Correlation Between the Acquisition of Resistance to Gemcitabine Therapy and the Expression of HuR in Pancreatic Ductal Adenocarcinoma: A Case Report INTERNATIONAL SURGERY. 2018; 103 (1-2): 116-120. ( DOI )

Oba A, Kudo A, Kishino M , Akashi T, Katsuta E, Akahoshi E, Iwao Y, Ono H, Mitsunori Y, Ban D , Tanaka S, Eishi Y, Tateishi U, Tanabe M. A simple morphological classification to estimate the malignant potential of pancreatic neuroendocrine tumors. Journal of Gastroenterology. 2017.10; 52 (10): 1140-1146. ( PubMed, DOI )

Ishikawa Y, Ban D, Matsumura S, Mitsunori Y, Ochiai T, Kudo A, Tanaka S, Tanabe M. Surgical pitfalls of jejunal vein anatomy in pancreaticoduodenectomy. J Hepatobiliary Pancreat Sci. 2017.07; 4 (7): 394-400. ( DOI )

Ueda H, Ban D, Akahoshi K, Mitsunori Y, Matsumura S, Ochiai T, Kudo A, Tanaka S, Tanabe M. Refractory long-term cholangitis after pancreaticoduodenectomy: a retrospective study. World Journal of Surgery. 2017.07; 41 (7): 1882-1889. ( DOI )

Ohata Y, Shimada S, Akiyama Y, Mogushi K, Ito H, Matsumura S, Aihara A, Mitsunori Y, Ban D, Ochiai T, Kudo A, Tanabe M, Tanaka S . Acquired resistance with epigenetic alterations under long-term anti-angiogenic therapy for hepatocellular carcinoma. Molecular Cancer Therapeutics. 2017.06; 16 (6): 1155-1165. ( DOI )

Ohata Yoshiteru, Shimada Shu, Akiyama Yoshimitsu, Mogushi Kaoru, Nakao Keisuke, Matsumura Satoshi, Aihara Arihiro, Mitsunori Yusuke, Ban Daisuke, Ochiai Takanori, Kudo Atsushi, Arii Shigeki, Tanabe Minoru, Tanaka Shinji. Acquired Resistance with Epigenetic Alterations Under Long-Term Antiangiogenic Therapy for Hepatocellular Carcinoma MOLECULAR CANCER THERAPEUTICS. 2017.06; 16 (6): 1155-1165. ( PubMed, DOI )

Oba A, Shimada S, Akiyama Y, Nishikawaji T, Mogushi K, Ito H, Matsumura S, Aihara A, Mitsunori Y, Ban D, Ochiai T, Kudo A, Asahara H, Kaida A, Miura M, Tanabe M, Tanaka S . ARID2 modulates DNA damage response in human hepatocellular carcinoma cells. Journal of Hepatology. 2017.05; 66 (5): 942-951. ( DOI )

Akahoshi K, Ochiai T, Takaoka A, Kitamura T, Ban D, Kudo A, Tanaka S, Tanabe M. Emergency Cholecystectomy for Patients on Antiplatelet Therapy. Am Surg. 2017.05; 83 (5): 486-490. ( PubMed )

Ban Daisuke, Asano Daisuke, Akahoshi Keiichi, Ono Hiroaki, Mitsunori Yusuke, Kudo Atsushi, Tanaka Shinji, Tanabe Minoru. Borderline resectable膵癌に対するCT画像の特徴に応じた至適管理(The optimal management depending on the features of CT imaging of borderline resectable pancreatic cancer) Journal of Hepato-Biliary-Pancreatic Sciences. 2017.05; 24 (Suppl.1): A165. ( ichushi )

Chiyonobu Norimichi, Ono Hiroaki, Iwao Yasuhito, Matsumura Satoshi, Mitsunori Yusuke, Ban Daisuke, Ochiai Takanori, Kudo Atsushi, Tanaka Shinji, Tanabe Minoru. IPMNの術前画像検査において造影される結節の臨床的意義(Clinical significance of enhancing nodules in preoperative imaging studies of IPMN) Journal of Hepato-Biliary-Pancreatic Sciences. 2017.05; 24 (Suppl.1): A369. ( ichushi )

Ono Hiroaki, Akahoshi Keiichi, Iwao Yasuhito, Matsumura Satoshi, Mitsunori Yuusuke, Ban Daisuke, Ochiai Takanori, Kudo Atsushi, Tanaka Shinji, Tanabe Minoru. IPMNに対する手術後におけるリンパ節転移の臨床評価(Clinical evaluation of lymph node metastasis after surgery of IPMN) Journal of Hepato-Biliary-Pancreatic Sciences. 2017.05; 24 (Suppl.1): A115. ( ichushi )

Akahoshi Keiichi, Ochiai Takanori, Takaoka Ayumi, Kitamura Takuya, Ban Daisuke, Kudo Atsushi, Tanaka Shinji, Tanabe Minoru. Emergency Cholecystectomy for Patients on Antiplatelet Therapy AMERICAN SURGEON. 2017.05; 83 (5): 486-490.

Kawai-Kitahata F., Asahina Y., Kakinuma S., Murakawa M., Nitta S., Nagata H., Kaneko S., Otani S., Asano Y., Inoue E., Miyoshi M., Tsunoda T., Sato A., Nakagawa M., Itsui Y., Azuma S., Tanaka S., Tanabe M., Maekawa S., Enomoto N., Watanabe M.. Genetic differences in hepatocellular carcinoma among chronic persistent hepatitis B virus infection with or without viral suppression and prior hepatitis B virus infection JOURNAL OF HEPATOLOGY. 2017; 66 (1): S227.

Furuyama T, Kudo A, Matsumura S, Mitsunori Y, Aihara A, Ban D, Ochiai T, Tanaka S, Tanabe M. Preoperative direct bilirubin to prothrombin time ratio index to prevent liver failure after minor hepatectomy J Hepatobiliary Pancreat Sci. 2016.12; 23 (12): 763-770. ( DOI )

Munakata K, Uemura M, Tanaka S, Kawai K, Kitahara T, Miyo M, Kano Y, Nishikawa S, Fukusumi T, Takahashi Y, Hata T, Nishimura J, Takemasa I, Mizushima T, Ikenaga M, Kato T, Murata K, Carethers JM, Yamamoto H, Doki Y, Mori M. Cancer stem-like properties in colorectal cancer cells with low proteasome activity Clinical Cancer Research. 2016.11; 22 (21): 5277-5286.

Watanabe Y, Honda S, Konishi A, Satoko Arakawa S, Murohashi M, Yamaguchi H, Torii S, Tanabe M, Tanaka S, Warabi E, Shimizu S. Autophagy controls centrosome number by degrading Cep63. Nature Communications. 2016.11; 21 (7): 13508. ( DOI )

Nishikawaji T, Akiyama Y, Shimada S, Kojima K, Kawano T, Eishi Y, Yuasa Y, Tanaka S. Overexpression of histone methyltransferase SETDB2 acts an oncogene in gastric cancer Oncotarget. 2016.10; 7 (41): 67251-67265. ( DOI )

Akahoshi K, Tanaka S, Mogushi K, Shimada S, Matsumura S, Akiyama Y, Aihara A, Mitsunori Y, Ban D, Ochiai T, Kudo A, Arii S, Tanabe M.. Expression of connective tissue growth factor in the livers of non-viral hepatocellular carcinoma patients with metabolic risk factors. J Gastroenterol. . 2016.09; 51 (9): 910-922.

Akahoshi K, Tanaka S, Mogushi K, Shimada S, Matsumura S, Akiyama Y, Aihara A, Mitsunori Y, Ban D, Ochiai T, Kudo A, Arii S, Tanabe M. Expression of connective tissue growth factor in the livers of non-viral hepatocellular carcinoma patients with metabolic risk factors Journal of Gastroenterology. 2016.09; 51 (9): 910-922. ( DOI )

Oba A, Ban D, Kirimura S, Akahoshi K, Mitsunori Y, Matsumura S, Ochiai T, Kudo A, Tanaka S, Minoru T.. Clinical application of the biomarkers for the selection of adjuvant chemotherapy in pancreatic ductal adenocarcinoma. J Hepatobiliary Pancreat Sci. . 2016.08; 23 (8): 480-488.

Tanaka S. Cancer stem cells as therapeutic targets Human Stem Cell Toxicity (ed. Sherley JL). 2016.08; 280-294. ( DOI )

Oba A, Ban D, Kirimura S, Akahoshi K, Mitsunori Y, Matsumura S, Ochiai T, Kudo A, Tanaka S, Tanabe M. . Clinical application of the biomarkers for the selection of adjuvant chemotherapy in pancreatic ductal adenocarcinoma. J Hepatobiliary Pancreat Sci. 2016.08; 23 (8): 480-488. ( DOI )

Eriko Katsuta, Atsushi Kudo, Takumi Akashi, Yusuke Mitsunori, Satoshi Matsumura, Arihiro Aihara, Daisuke Ban, Takanori Ochiai, Shinji Tanaka, Yoshinobu Eishi, Minoru Tanabe. Macroscopic morphology for estimation of malignant potential in pancreatic neuroendocrine neoplasm J Cancer Res Clin Oncol . 2016.06; 142 1299-1306.

Katsuta E, Kudo A, Akashi T, Mitsunori Y, Matsumura S, Aihara A, Ban D, Ochiai T, Tanaka S, Eishi Y, Tanabe M. Macroscopic morphology for estimation of malignant potential in pancreatic neuroendocrine neoplasm Journal of Cancer Research and Clinical Oncology. 2016.06; 142 (6): 1299-1309. ( DOI )

Furuyama T, Tanaka S, Shimada S, Akiyama Y, Matsumura S, Mitsunori Y, Aihara A, Ban D, Ochiai T, Kudo A, Fukamachi H, Arii S, Kawaguchi Y, Tanabe M. Proteasome activity is required for the initiation of precancerous pancreatic lesions Scientific Reports. 2016.05; 6 27044. ( DOI )

4) Kawai-Kitahata F, Asahina Y, Tanaka S, Kakinuma S, Murakawa M, Sayuri Nitta S, Watanabe T, Otani S, Taniguchi M, Goto F, Nagata H, Kaneko S, Tasaka-Fujita M, Nishimura-Sakurai Y, Azuma S, Itsui Y, Nakagawa M, Tanabe M, Takano S, Fukasawa M, Sakamoto M, Maekawa S, Enomoto N, Watanabe M. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. Journal of Gastroenterology. 2016.05; 51 (5): 473-486. ( DOI )

Yamada N, Yasui K, Dohi O, Gen Y, Tomie A, Kitaichi T, Iwai N, Mitsuyoshi H, Sumida Y, Moriguchi M, Yamaguchi K, Nishikawa T, Umemura A, Naito Y, Tanaka S, Arii S, Itoh Y. Genome-wide DNA methylation analysis in hepatocellular carcinoma Oncology Reports. 2016.04; 35 (4): 2228-2236. ( DOI )

Tanaka S.. Molecular pathogenesis and targeted therapy of pancreatic cancer. Annals of Surgical Oncology. 2016.02; Suppl (2): 197-205.

4) Katsuta E, Tanaka S, Mogushi K, Shimada S, Akiyama Y, Aihara A, Matsumura S, Mitsunori Y, Ban D, Ochiai T, Kudo A, Fukamachi H, Tanaka H, Nakayama K, Arii S, Tanabe M . CD73 as a therapeutic target for pancreatic neuroendocrine tumor stem cells International Journal of Oncology. 2016.02; 48 (2): 657-669.

Katsuta E, Tanaka S, Mogushi K, Shimada S, Akiyama Y, Aihara A, Matsumura S, Mitsunori Y, Ban D, Ochiai T, Kudo A, Fukamachi H, Tanaka H, Nakayama K, Arii S, Tanabe M.. CD73 as a therapeutic target for pancreatic neuroendocrine tumor stem cells. Int J Oncol. . 2016.02; 48 (2): 657-669.

Nakao K, Tanaka S, Miura T, Sato K, Matsumura S, Aihara A, Mitsunori Y, Ban D, Ochiai T, Kudo A, Arii S, Tanabe M. A novel Aurora/VEGFR dual kinase inhibitor as treatment for hepatocellular carcinoma Cancer Science. 2015; 106 (8): 1016-1022.

Ban D, Kudo A, Irie T, Ochiai T, Aihara A, Matusmura S, Tanaka S, Tanabe M. Advances in reduced port laparoscopic liver resection Asian Journal of Endoscopic Surgery. 2015; 8 (1): 11-15.

Tanaka S. Cancer stem cells as therapeutic targets of hepato-biliary-pancreatic cancers Journal of Hepato-Biliary-Pancreatic Sciences. 2015; 22 (7): 531-537.

Watanabe Y, Yamamoto H, Oikawa R, Toyota M, Yamamoto M, Kokudo N, Tanaka S, Arii S, Yotsuyanagi H, Koike K, Itoh F. DNA methylation at hepatitis B viral integrants is associated with methylation at flanking human genomic sequences Genome Research. 2015; 25 (3): 328-337.

Yasui K, Konishi C, Gen Y, Endo M, Dohi O, Tomie A, Kitaichi T, Yamada N, Iwai N, Nishikawa T, Yamaguchi K, Moriguchi M, Sumida Y, Mitsuyoshi H, Tanaka S, Arii S, Itoh Y. EVI1, a target gene for amplification at 3q26, antagonizes TGF-beta-mediated growth inhibition in hepatocellular carcinoma Cancer Science. 2015; 106 (7): 929-937.

Ban D, Kudo A, Ito H, Mitsunori Y, Matsumura S, Aihara A, Ochiai T, Tanaka S, Tanabe M, Itano O, Kaneko H, Wakabayashi G. The difficulty of laparoscopic liver resection Updates in Surgery. 2015; 67 (2): 123-128.

Okajima C, Arii S, Tanaka S, Matsumura S, Ban D, Ochiai T, Irie T, Kudo A, Nakamura N, Tanabe M. Prognostic role of Child-Pugh score 5 and 6 in hepatocellular carcinoma patients who underwent curative hepatic resection American Journal of Surgery. 2015; 209 (1): 199-205.

Sakamoto A, Akiyama Y, Shimada S, Zhu WG, Yuasa Y, Tanaka S. DNA methylation in the exon 1 region and complex regulation of Twist1 expression in gastric cancer PLoS ONE. 2015; 10 (12): e0145630.

Miura T, Ban D, Tanaka S, Mogushi K, Kudo A, Matsumura S, Mitsunori Y, Ochiai T, Tanaka H, Tanabe M. Distinct clinicopathological phenotype of hepatocellular carcinoma with EOB-MRI hyperintensity: association with gene expression signature American Journal of Surgery. 2015; 210 (3): 561-569.

Matsunaga H, Tanaka S, Aihara A, Ogawa K, Matsumura S, Ban D, Ochiai T, Irie T, Kudo A, Nakamura N, Arii S, Tanabe M. A novel therapeutic combination targeting sequentially Aurora B and Bcl-xL in hepatocellular carcinoma Annals of Surgical Oncology. 2015; 22 (9): 3079-3086.

Kudo A, Matusmura S, Ban D, Irie T, Ochiai T, Tanaka S, Arii S, Tanabe M.. Does the preoperative alpha-fetoprotein predict the recurrence and mortality after hepatectomy for hepatocellular carcinoma without macrovascular invasion in patients with normal liver function? Hepatol. Res.. 2014.12; 44 (14): E437-E446. ( PubMed, DOI )

Matsunaga H, Tanaka S, Aihara A, Ogawa K, Matsumura S, Ban D, Ochiai T, Irie T, Kudo A, Nakamura N, Arii S, Tanabe M.. A Novel Therapeutic Combination Sequentially Targeting Aurora B and Bcl-xL in Hepatocellular Carcinoma. Ann. Surg. Oncol.. 2014.12; ( PubMed, DOI )

Kudo A, Tanaka S, Ban D, Matsumura S, Irie T, Ochiai T, Nakamura N, Arii S, Tanabe M.. Alcohol consumption and recurrence of non-B or non-C hepatocellular carcinoma after hepatectomy: a propensity score analysis. J. Gastroenterol.. 2014.09; 49 (9): 1352-1361. ( PubMed, DOI )

Kudo A, Tanaka S, Matsumura S, Ban D, Irie T, Ochiai T, Nakamura N, Arii S.. Anatomic resection reduces the recurrence of solitary hepatocellular carcinoma ≤5 cm without macrovascular invasion. Am. J. Surg.. 2014.06; 207 (6): 863-869. ( PubMed, DOI )

Miura T, Ban D, Koyama T, Kudo A, Ochiai T, Irie T, Nakamura N, Tanaka S, Arii S.. Severe postoperative hemorrhage caused by antibody-mediated coagulation factor deficiencies: report of two cases. Surg. Today. 2014.05; 44 (5): 976-981. ( PubMed, DOI )

Katsuta E, Tanaka S, Mogushi K, Matsumura S, Ban D, Ochiai T, Irie T, Kudo A, Nakamura N, Tanaka H, Tanabe M, Arii S.. Age-related clinicopathologic and molecular features of patients receiving curative hepatectomy for hepatocellular carcinoma. Am. J. Surg.. 2014.05; ( PubMed, DOI )

Kudo A, Igari T, Kumagai J, Tanaka S, Ban D, Noguchi N, Irie T, Nakamura N, Arii S.. A simple index to predict liver functional reserve after hepatectomy. Hepatogastroenterology. 2014.04; 61 712-716.

Ogawa K, Tanaka S, Matsumura S, Murakata A, Ban D, Ochiai T, Irie T, Kudo A, Nakamura N, Tanabe M, Arii S.. EpCAM-targeted therapy for human hepatocellular carcinoma. Ann. Surg. Oncol.. 2014.04; 21 (4): 1314-1322. ( PubMed, DOI )

Kudo A, Mogushi K, Takayama T, Matsumura S, Ban D, Irie T, Ochiai T, Nakamura N, Tanaka H, Anzai N, Sakamoto M, Tanaka S, Arii S.. Mitochondrial metabolism in the noncancerous liver determine the occurrence of hepatocellular carcinoma: a prospective study. J. Gastroenterol.. 2014.03; 49 (3): 502-510. ( PubMed, DOI )

Yasui Y, Kudo A, Kurosaki M, Matsuda S, Muraoka M, Tamaki N, Suzuki S, Hosokawa T, Ueda K, Matsunaga K, Nakanishi H, Tsuchiya K, Itakura J, Takahashi Y, Tanaka S, Asahina Y, Enomoto N, Arii S, Izumi N.. Reduced organic anion transporter expression is a risk factor for hepatocellular carcinoma in chronic hepatitis C patients: a propensity score matching study. Oncology. 2014.01; 86 (1): 53-62. ( PubMed, DOI )

Kano Y, Konno M, Kawamoto K, Tamari K, Hayashi K, Fukusumi T, Satoh T, Tanaka S, Ogawa K, Mori M, Doki Y, Ishii H. Novel drug discovery system for cancer stem cells in human squamous cell carcinoma of the esophagus. Oncology Reports. 2014; 86 (1): 53-62.

Sato K, Tanaka S, Mitsunori Y, Mogushi K, Yasen M, Aihara A, Ban D, Ochiai T, Irie T, Kudo A, Nakamura N, Tanaka H, Arii S.. Contrast-enhanced intraoperative ultrasonography for vascular imaging of hepatocellular carcinoma; clinical and biological significance. Hepatology. 2013; 57 (4): 1436-1447. ( PubMed, DOI )

Muramatsu S, Tanaka S, Mogushi K, Adikrisna R, Aihara A, Ban D, Ochiai T, Irie T, Kudo A, Nakamura N, Tanaka H, Nakayama K, Tanaka H, Yamaoka S, Arii S. . Muramatsu S, Tanaka S, Mogushi K, Adikrisna R, Aihara A, Ban D, Ochiai T, Irie T, Kudo A, Nakamura N, Tanaka H, Nakayama K, Tanaka H, Yamaoka S, Arii S. Visualization of stem cell features in human hepatocellular carcinoma enlightened in vivo significance of tumor-host interaction and clinical implication. Hepatology, 58:218-228, 2013 Hepatology. 2013; 58 218 -228.

Adikrisna R, Tanaka S, Muramatsu S, Aihara A, Ban D, Ochiai T, Irie T, Kudo A, Nakamura N, Yamaoka S, Arii S. Adikrisna R, Tanaka S, Muramatsu S, Aihara A, Ban D, Ochiai T, Irie T, Kudo A, Nakamura N, Yamaoka S, Arii S. Identification of pancreatic cancer stem cells and selective toxicity of chemotherapeutic agents. Gastroenterology, 143:234-245, 2012 Gastroenterology, 143:234-245, 2012 . 2012;

Matsumura S, Imoto I, Kozaki K, Matsui T, Muramatsu T, Furuta M, Tanaka S, Sakamoto M, Arii S, Inazawa J. . Matsumura S, Imoto I, Kozaki K, Matsui T, Muramatsu T, Furuta M, Tanaka S, Sakamoto M, Arii S, Inazawa J. Integrative array-based approach identifies MZB1 as a frequently methylated putative tumor-suppressor in hepatocellular carcinoma. Clinical Cancer Research, 18:3541-3551, 2012 Clinical Cancer Research, 18:3541-3551, 2012. 2012;

Tanaka S, Arii S.. Tanaka S, Arii S. Molecular targeted therapy in hepatocellular carcinoma. Seminars in Oncology, 39:486-92, 2012 Seminars in Oncology, 39:486-92, 2012. 2012;

Tanaka S, Mogushi K, Yasen M, Ban D, Noguchi N, Kudo A, Nakamura N, Tanaka H, Yamamoto M, Kokudo N, Takayama T, Kawasaki S, Sakamoto M, Arii S. . Tanaka S, Mogushi K, Yasen M, Ban D, Noguchi N, Kudo A, Nakamura N, Tanaka H, Yamamoto M, Kokudo N, Takayama T, Kawasaki S, Sakamoto M, Arii S. Oxidative stress pathways in non-cancerous human liver tissue to predict hepatocellular carcinoma recurrence; a prospective multi-center study. Hepatology, 54:1273-1281, 2011 Hepatology, 54:1273-1281, 2011. 2011;

Murakata A, Tanaka S, Mogushi K, Yasen M, Noguchi N, Irie T, Kudo A, Nakamura N, Tanaka H, Arii S. Murakata A, Tanaka S, Mogushi K, Yasen M, Noguchi N, Irie T, Kudo A, Nakamura N, Tanaka H, Arii S. Gene expression signature of the gross morphology in hepatocellular carcinoma. Annals of Surgery, 253:94-100, 2011 Annals of Surgery, 253:94-100, 2011. 2011;

Aihara A, Tanaka S, Yasen M, Matsumura S, Mitsunori Y, Murakata A, Noguchi N, Kudo A, Nakamura N, Ito K, Arii S. Aihara A, Tanaka S, Yasen M, Matsumura S, Mitsunori Y, Murakata A, Noguchi N, Kudo A, Nakamura N, Ito K, Arii S. The selective Aurora B kinase inhibitor AZD1152 as a novel treatment for hepatocellular carcinoma. Journal of Hepatology, 52:63-71, 2010 Journal of Hepatology, 52:63-71, 2010. 2010;

Tanaka S, Arii S.. Tanaka S, Arii S. Molecularly targeted therapy for hepatocellular carcinoma. Cancer Science, 100:1-8, 2009 Cancer Science, 100:1-8, 2009. 2009;

Tanaka S, Arii S, Yasen M, Mogusi K, Su N-T, Zhao C, Imoto I, Eishi Y, Inazawa J, Miki Y, Tanaka H.. Tanaka S, Arii S, Yasen M, Mogusi K, Su N-T, Zhao C, Imoto I, Eishi Y, Inazawa J, Miki Y, Tanaka H. Aurora kinase B is a predictive factor for aggressive recurrence of hepatocellular carcinoma after curative hepatectomy. British Journal of Surgery, 95:611-619, 2008 British Journal of Surgery, 95:611-619, 2008. 2008;

Tanaka S, Noguchi N, Ochiai T, Kudo A, Nakamura N, Ito K, Kawamura T, Teramoto K, Arii S. . Tanaka S, Noguchi N, Ochiai T, Kudo A, Nakamura N, Ito K, Kawamura T, Teramoto K, Arii S. Outcomes and recurrence of initially resection of hepatocellular carcinoma meeting Milan criteria: Rationale for partial hepatectomy as first strategy. Journal of the American College of Surgeons, 204:1-6, 2007 Journal of the American College of Surgeons, 204:1-6, 2007. 2007;

Tanaka S, Pero SC, Taguchi K, Shimada M, Mori M, Krag DN, Arii S. Tanaka S, Pero SC, Taguchi K, Shimada M, Mori M, Krag DN, Arii S. Specific peptide ligand for Grb7 signal transduction protein and pancreatic cancer metastasis. Journal of the National Cancer Institute, 98:491-498, 2006 Journal of the National Cancer Institute, 98:491-498, 2006. 2006;

Merle P, Kim M, Herrmann M, Gupte A, Lefrancois L, Califano S, Trepo C, Tanaka S, Vitvitski L, Monte SD, Wands JR. Merle P, Kim M, Herrmann M, Gupte A, Lefrancois L, Califano S, Trepo C, Tanaka S, Vitvitski L, Monte SD, Wands JR. Oncogenic role of the frizzled-7/beta-catenin pathway in hepatocellular carcinoma. Journal of Hepatology, 43:854-62, 2005 Journal of Hepatology, 43:854-62, 2005. 2005;

Harimoto N, Taketomi A, Kitagawa D, Kuroda Y, Itoh S, Gion T, Tanaka S, Shirabe K, Shimada M, Maehara Y. Harimoto N, Taketomi A, Kitagawa D, Kuroda Y, Itoh S, Gion T, Tanaka S, Shirabe K, Shimada M, Maehara Y. The newly established human hepatocyte cell line: application for the bioartificial liver. Journal of Hepatology, 42:557-64, 2005 Journal of Hepatology, 42:557-64, 2005. 2005;

Osoegawa A, Yoshino I, Tanaka S, Sugio K, Kameyama T, Yamaguchi M, Maehara Y. . Osoegawa A, Yoshino I, Tanaka S, Sugio K, Kameyama T, Yamaguchi M, Maehara Y. Regulation of p27 by S-phase kinase-associated protein 2 is associated with aggressiveness in non-small-cell lung cancer. Journal of Clinical Oncology, 22:4165-73, 2004 Journal of Clinical Oncology, 22:4165-73, 2004. 2004;

Maehara Si, Tanaka S, Saito , Shirabe K, Maehara Y. . Maehara Si, Tanaka S, Saito , Shirabe K, Maehara Y. Selenoprotein P, as a predictor for evaluating gemcitabine resistance in human pancreatic cancer cells. International Journal of Cancer, 112:184-9, 2004 International Journal of Cancer, 112:184-9, 2004. 2004;

Merle P, de la Monte S, Kim M, Herrmann M, Tanaka S, Von Dem Bussche A, Kew MC, Trepo C, Wands JR. . Merle P, de la Monte S, Kim M, Herrmann M, Tanaka S, Von Dem Bussche A, Kew MC, Trepo C, Wands JR. Functional consequences of frizzled-7 receptor overexpression in human hepatocellular carcinoma. Gastroenterology, 127(4):1110-22, 2004 Gastroenterology, 127(4):1110-22, 2004. 2004;

Tanaka S, Sugimachi K, Kameyama T, Maehara Si, Shirabe K, Shimada M, Wands JR, Maehara Y. . Tanaka S, Sugimachi K, Kameyama T, Maehara Si, Shirabe K, Shimada M, Wands JR, Maehara Y. Human WISP1v, a member of CCN family, is associated with invasive cholangiocarcinoma. Hepatology, 37:1122-9, 2003 Hepatology, 37:1122-9, 2003. 2003;

Tanaka S, Sugimachi K, Maehara Si, Shimada M, Maehara Y. . Tanaka S, Sugimachi K, Maehara Si, Shimada M, Maehara Y. A loss of function mutation in WISP3 derived from microsatellite unstable gastric carcinoma. Gastroenterology, 125:1563-4, 2003 Gastroenterology, 125:1563-4, 2003. 2003;

Tanaka S, Sugimachi K, Yamashita Yi, Ohga T, Shirabe K, Shimada M, Wands JR, Sugimachi K. . Tanaka S, Sugimachi K, Yamashita Yi, Ohga T, Shirabe K, Shimada M, Wands JR, Sugimachi K. Tie2 vascular endothelial receptor expression and function in hepatocellular carcinoma. Hepatology, 35:861-7, 2002 Hepatology, 35:861-7, 2002. 2002;

Tanaka S, Sugimachi K, Shimada M, Maehara Y, Sugimachi K. . Tanaka S, Sugimachi K, Shimada M, Maehara Y, Sugimachi K. Variant WISPs as targets for gastrointestinal carcinomas. Gastroenterology, 123:392-3, 2002 Gastroenterology, 123:392-3, 2002. 2002;

Tanaka S, Sugimachi K, Saeki H, Kinoshita J, Ohga T, Shimada M, Maehara Y, Sugimachi K. . Tanaka S, Sugimachi K, Saeki H, Kinoshita J, Ohga T, Shimada M, Maehara Y, Sugimachi K. A novel variant of WISP1 lacking a Von Willebrand type C module overexpressed in scirrhous gastric carcinoma. Oncogene, 20:5525-32, 2001 Oncogene, 20:5525-32, 2001. 2001;

Sugimachi K, Aishima S, Taguchi K, Tanaka S, Shimada M, Kajiyama K, Sugimachi K, Tsuneyoshi M. . Sugimachi K, Aishima S, Taguchi K, Tanaka S, Shimada M, Kajiyama K, Sugimachi K, Tsuneyoshi M. The role of overexpression and gene amplification of cyclin D1 in intrahepatic cholangiocarcinoma. Journal of Hepatology, 35:74-79, 2001 Journal of Hepatology, 35:74-79, 2001. 2001;

Etoh T, Inoue H, Tanaka S, Bernard GF, Kitano S, Mori M. . Etoh T, Inoue H, Tanaka S, Bernard GF, Kitano S, Mori M. Angiopoietin-2 is related to tumor angiogenesis in gastric carcinoma: Possible in vivo regulation via induction of proteases. Cancer Research, 61:2145-2153, 2001 Cancer Research, 61:2145-2153, 2001. 2001;

Yamashita Yi, Shimada M, Hamatsu T, Rikimaru T, Tanaka S, Shirabe K, Sugimachi K. . Yamashita Yi, Shimada M, Hamatsu T, Rikimaru T, Tanaka S, Shirabe K, Sugimachi K. Electroporation-mediated interleukin-12 gene therapy for hepatocellular carcinoma in the mice model. Cancer Research, 61:1005–1012, 2001 Cancer Research, 61:1005–1012, 2001. 2001;

Tanaka S, Sugimachi K, Shirabe K, Shimada M, Wands JR, Sugimachi K. . Tanaka S, Sugimachi K, Shirabe K, Shimada M, Wands JR, Sugimachi K. Expression and anti-tumor effects of TRAIL in human cholangiocarcinoma. Hepatology, 32:523-527, 2000 Hepatology, 32:523-527, 2000. 2000;

Tanaka S, Mori M, Sakamoto Y, Makuuchi M, Sugimachi K, Wands JR. Biologic significance of angiopoietin-2 expression in human hepatocellular carcinoma. Journal of Clinical Investigation, 103(3): 341-5, 1999 1999;

Fujie T, Tanaka F, Tahara K, Li J, Tanaka S, Mori M, Ueo H, Takesako K, Akiyoshi T. Generation of specific antitumor reactivity by the stimulation of spleen cells from gastric cancer patients with MAGE-3 synthetic peptide. Cancer Immunology and Immunotherapy, 48(4): 189-94, 1999 1999;

Tokumitsu Y, Mori M, Tanaka S, Akazawa K, Nakano S, Niho Y. Prognostic significance of polo-like kinase expression in esophageal carcinoma. International Journal of Oncology, 15(4): 687-92, 1999 1999;

Shibata K, Tanaka S, Shiraishi T, Kitano S, Mori M. G-protein gamma 7 is down-regulated in cancers and associated with p 27kip1-induced growth arrest. Cancer Research, 59(5): 1096-101, 1999 Cancer Research, 59(5): 1096-101, 1999. 1999;

Watanabe M, Kuwano H, Tanaka S, Toh Y, Sadanaga N, Sugimachi K. Flow cytometric DNA analysis is useful in detecting multiple genetic alterations in squamous cell carcinoma of the esophagus. Cancer, 85(11): 2322-8, 1999 1999;

Shimada M, Hasegawa H, Gion T, Shirabe K, Taguchi K, Takenaka K, Tanaka S, Sugimachi K. Risk factors of the recurrence of hepatocellular carcinoma originating from residual cancer cells after hepatectomy. Hepatogastroenterology, 46(28): 2469-75, 1999 1999;

Watanabe M, Kuwano H, Tanaka S, Toh Y, Masuda H, Sugimachi K. A significant morphological transformation is recognized in human esophageal cancer cells with an amplification/overexpression of the Cyclin D1 gene. International Journal of Oncology, 15(6): 1103-1108, 1999 1999;

Mori M, Shiraishi T, Tanaka S, Yamagata M, Mafune K, Tanaka Y, Ueo H, Barnard GF, Sugimachi K. Lack of DMBT1 expression in oesophageal, gatric and colon cancer. British Journal of Cancer, 79(2): 211-213, 1999 1999;

de la Monte SM, Ganju N, Tanaka S, Banerjee K, Karl PJ, Brown NV, Wands JR.. Differential effects of ethanol on insulin-signaling through the insulin receptor substrate-1. Alcoholism, Clinical and Experimental Research. 1999; 23 (5): 770-777. ( PubMed, DOI )

Tanaka S, Komori K, Sugimachi K. Cytomegalovirus infection in aortic aneurysms. Journal of Vascular Surgery, 27(3): 587-588, 1998 1998;

Mohr L, Tanaka S, Wands JR. Ethanol inhibits hepatocytes proliferation through the IRS-1 signal transduciton pathway in transgene mice. Gastroenterology, 115(6): 1558-65, 1998 1998;

Shiraishi T, Mori M, Tanaka S, Sugimachi K, Akiyoshi T. Identification of cystatin B in human esophageal carcinoma using differential displays in which the gene expression is related to lymph node metastasis. International Journal of Cancer, 79(2): 175-178, 1998 1998;

Mimori K, Mori M, Shiraishi T, Tanaka S, Haraguchi M, Ueo H, Shirasaka C, Akiyoshi. Expression of ornithine decarboxylase mRNA and c-myc mRNA in breast tumours. International Journal of Oncology, 12(3):597-601, 1998 1998;

Yonemitsu Y, Kaneda Y, Tanaka S, Nakashima Y, Komori K, Sugimachi K, Sueishi K. Transfer of wild-type p53 gene effectively inhibits vascular smooth muscle cell proliferation in vitro and in vivo. Circulation Research, 82(2): 147-156, 1998 1998;

Shibata K, Mori M, Tanaka S, Kitano S, Akiyoshi T. Identification and cloning of human G-protein gamma 7, down-regulated in pancreatic cancer. Biochemical and Biophysical Research Communications, 246(1): 205-209, 1998 1998;

Tanaka S, Mori M, Akiyoshi T, Tanaka Y, Mafune K, Wands JR, Sugimachi K.. Tanaka S, Mori M, Akiyoshi T, Tanaka Y, Mafune K, Wands JR, Sugimachi K. A novel variant of human Grb7 is associated with invasive esophageal carcinoma. Journal of Clinical Investigation, 102(4): 821-827, 1998 Journal of Clinical Investigation, 102(4): 821-827, 1998. 1998;

Tanaka S, Akiyoshi T, Mori M, Wands JR, Sugimachi K. . Tanaka S, Akiyoshi T, Mori M, Wands JR, Sugimachi K. A novel frizzled gene identified in human esophageal carcinoma mediates APC/beta-catenin signals. Proceedings of the National Academy of Sciences, USA, 95(17): 10164-10169, 1998 Proceedings of the National Academy of Sciences, USA, 95(17): 10164-10169, 1998. 1998;

Tanaka S, Mori M, Akiyoshi T, Tanaka Y, Mafune K, Wands JR, Sugimachi K. Co-expression of Grb7 with EGFR or Her2/erbB2 in human advanced esophageal carcinoma. Cancer Research, 57: 28-31, 1997 1997;

Mimori K, Mori M, Begum NA, Tanaka S, Haraguchi M, Ueo H, Karimine N, Akiyoshi T, Barnard GF. Clinical significance of integrin alpha 6 mRNA expression in gastric carcinoma. International Journal of Oncology, 11(5): 959-964, 1997 1997;

Wands JR, Lavaissiere L, Moradopour D, de la Monte S, Mohr L, Nicolau C, Tanaka S. Immunological approach to hepatocellular carcinoma. Journal of Viral Hepatitis, 4(4): 60-74, 1997 1997;

Mori M, Mimori K, Shiraishi T, Tanaka S, Ueo H, Sugimachi K, Akiyoshi T. p27 expression and gastric carcinoma. Nature Medicine, 3(6): 593, 1997 1997;

Tanaka S, Smidt EV, Mohr L, Sugimachi K, Wands JR. Biological effects of human insulin receptor substrate-1 overexpression in hepatocytes. Hepatology, 26: 598-604, 1997 1997;

Tanaka S, Takenaka K, Matsumata T, Mori R, Sugimachi K. Hepatitis C virus replication is associated with expression of transforming growth factor-alpha and insulin-like growth factor-II in cirrhotic livers. Digestive Diseases and Sciences, 41(1): 208-15, 1996 1996;

Yonemitsu Y, Nakagawa K, Tanaka S, Mori R, Sugimachi K, Sueishi K. In situ detection of frequent and active infection of human cytomegalovirus in inflammatory abdominal aortic aneurysms: possible pathogenic role in sustained chronic inflammatory reaction. Laboratory Investigation, 74(4): 723-36, 1996 1996;

Tanaka S, Wands JR. Tanaka S, Wands JR. Insulin receptor substrate-1 overexpression in human hepatocellular carcinoma cells prevents transforming growth factor-beta1 induced apoptosis. Cancer Research, 56: 3391-4, 1996 Cancer Research, 56: 3391-4, 1996. 1996;

Tanaka S, Ito T, Wands JR.. Tanaka S, Ito T, Wands JR. Neoplastic transformation induced by insulin receptor substrate-1 overexpression requires an interaction with Grb2 and Syp signaling molecules. Journal of Biological Chemistry, 271(24): 14610-6, 1996 Journal of Biological Chemistry, 271(24): 14610-6, 1996 . 1996;

Tanaka S, Wands JR. Tanaka S, Wands JR. A carboxy-terminal truncated IRS-1 dominant negative protein reverses the human hepatocellular carcinoma malignant phenotype. Journal of Clinical Investigation, 98(9): 2100-8, 1996 Journal of Clinical Investigation, 98(9): 2100-8, 1996. 1996;

Mimori K, Mori M, Tanaka S, Akiyoshi T, Sugimachi K. The overexpression of elongation factor 1 gamma mRNA in gastric carcinoma. Cancer, 75(6): 1446-9, 1995 1995;

Li YY, Minagawa H, Tanaka S, Mori R. Suppression of infectious virus spread to the liver by foscarnet following lethal infection of acyclovir-resistant herpes simplex virus type 2 in mice. Antiviral Research, 27(1-2): 111-21, 1995 1995;

Minagawa H, Tanaka S, Toh Y, Mori R. Detection of herpes simplex virus type 1-encoded RNA by polymerase chain reaction: different pattern of viral RNA detection in latently infected murine trigeminal ganglia following in vitro or in vivo reactivation. Journal of General Virology, 75(3): 647-50, 1994 1994;

Tanaka S, Komori K, Okadome K, Sugimachi K, Mori R. Detection of active cytomegalovirus infection in inflammatory aortic aneurysms with RNA polymerase chain reaction. Journal of Vascular Surgery, 20(2): 235-43, 1994 1994;

Mori M, Watanabe M, Tanaka S, Mimori K, Kuwano H, Sugimachi K. Epstein-Barr virus-associated carcinomas of the esophagus and stomach. Archives of Pathology & Laboratory Medicine, 118(10): 998-1001, 1994 1994;

Tanaka S, Toh Y, Adachi E, Matsumata T, Mori R, Sugimachi K. Tumor progression in hepatocellular carcinoma may be mediated by p53 mutation. Cancer Research, 53: 2884-7, 1993 1993;

Hayashi H, Sugio K, Matsumata T, Adachi E, Urata K, Tanaka S, Sugimachi K. The mutation of codon 249 in the p53 gene is not specific in Japanese hepatocellular carcinoma. Liver, 13(5): 279-81, 1993 1993;

Toh Y, Liu Y, Tanaka S, Mori R. Nucleotide sequence of the major DNA-binding protein gene of herpes simplex virus type 2 and a comparison with the type 1. Archives of Virology, 129(1-4): 183-96, 1993 1993;

Toh Y, Tanaka S, Liu Y, Hidaka Y, Mori R. Molecular characterization of naturally occurring glycoprotein C-negative herpes simplex virus type 1. Archives of Virology, 129(1-4): 119-30, 1993 1993;

Tanaka S, Toh Y, Mori R. Molecular analysis of a neurovirulent herpes simplex virus type 2 strain with reduced thymidine kinase activity. Archives of Virology, 131: 61-73, 1993 1993;

Tanaka S, Toh Y, Minagawa H, Mori R, Sugimachi K, Minamishima Y. Reactivation of cytomegalovirus in patients with cirrhosis: analysis of 122 cases. Hepatology, 16(6): 1409-14, 1992 1992;

Toh Y, Kuwano H, Tanaka S, Baba K, Matsuda H, Sugimachi K, Mori R. Detection of human papillomavirus DNA in esophageal carcinoma in Japan by polymerase chain reaction. Cancer, 70(9): 2234-8, 1992 1992;

Tanaka S, Toh Y, Mori R, Komori K, Okadome K, Sugimachi K. Possible role of cytomegalovirus in the pathogenesis of inflammatory aortic diseases. Journal of Vascular Surgery, 16(2): 274-9, 1992 1992;

Atsushi Nara, Keiichi Akahoshi, Hiroki Ueda,Koichiro Morimoto, Daisuke Asano, Shuichi Watanabe, Yoshiya Ishikawa, Hiroaki Ono, Atsushi Kudo, Shinji Tanaka,Minoru Tanabe. Usefulness of the Novel Rupture Severity Score (NRSS) in Determining the Timing of Transarterial Embolization (TAE) for Ruptured Hepatocellular Carcinoma. The 36th Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2024.06.29 Hiroshima

Hiroaki Ono, Daisuke Asano, Toshitaka Sugawara,Shuuichi Watanabe, Yoshiya Ishikawa, Hiroki Ueda, Keiichi Akahoshi, Atushi Kudo, Shinji Tanaka, Minoru Tanabe. Investigation of the usefulness of TNMG classification in pancreatic neuroendocrine tumors. The 36th Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2024.06.28 Hiroshima

Daisuke Asano, Keiichi Akahoshi, Yoshiya Ishikawa,Toshitaka Sugawara, Shuichi Watanabe, Hiroki Ueda,Hiroaki Ono, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. What is the safe and shortest way to learn laparoscopic liver surgery? DSS-based training system and safety use of CUSA. The 36th Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2024.06.28 Hiroshima

Akira Ito, Keiichi Akahoshi, Shotaro Gan, Atsushi Nara, Koichiro Morimoto, Hironari Yamashita, Daisuke Asano, Shuichi Watanabe, Yoshiya Ishikawa, Hiroki Ueda, Hiroaki Ono, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Prognostic Impact of Reticular Pattern around Superior Mesenteric Artery in CT Images of Pancreatic Cancer. The 3rd International Congress of the Asian Oncology Society 2023.10.20 Yokohama

Shotaro Gan, Daisuke Asano, Akira Ito, Atsushi Nara, Koichiro Morimoto, Hironari Yamashita, Shuichi Watanabe, Yoshiya Ishikawa, Hiroki Ueda, Keiichi Akahoshi, Hiroaki Ono, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Determining the Indication of Surgery for High grade pNENs. The 3rd International Congress of the Asian Oncology Society 2023.10.20 Yokohama

Atsushi Nara, Hiroki Ueda, Keiichi Akahoshi, Akira Ito, Shotaro Gan, Hironari Yamashita, Koichiro Morimoto, Daisuke Asano, Shuichi Watanabe, Yoshiya Ishikawa, Hiroaki Ono, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Preoperative sarcopenia assessment predicts loss of independence after Pancreaticoduodenectomy (PD) in pancreatic cancer patients. The 3rd International Congress of the Asian Oncology Society 2023.10.20 Yokohama

Hiroaki Ono, Keiichi Akahoshi, Shinji Tanaka, Minoru Tanabe. RRM1 is mediated by H3 acetylation through GEM resistance and contributes to invasiveness and ECM remodeling in PDAC. The 82nd Annual Meeting of the Japanese Cancer Association 2023.09.23 Yokohama

Hironari Yamashita, Hiroaki Ono, Kotaro Takizawa, Shuichi Watanabe, Kosuke Ogawa, Daisuke Asano, Yoshiya Ishikawa, Hiroki Ueda, Keiichi Akahoshi, Atsushi Kudo, Yoshimitsu Akiyama, Shinji Tanaka, Minoru Tanabe. PCNA-I1 is identified as a novel therapeutic agent in pancreatic cancer. The 82nd Annual Meeting of the Japanese Cancer Association 2023.09.23 Yokohama

Koya Yasukawa, Shu Shimada, Yoshimitsu Akiyama, Shinji Tanaka. Elucidation of immunotherapy resistance in hepatocellular carcinoma: Novel treatment based on lactate metabolism. The 82nd Annual Meeting of the Japanese Cancer Association 2023.09.22 Yokohama

Yoshimitsu Akiyama, Shu Shimada, Shinji Tanaka. Overexpression of PADI2 and histone citrullination change in gastric cancer. The 82nd Annual Meting of the Japanese Cancer Association 2023.09.21 Yokohama

Masahiro Yamane, Yoshiya Ishikawa, Masaru Takeuchi, Shotaro Gan, Kohei Yagi, Daisuke Asano, Shuichi Watanabe, Hiroki Ueda, Keiichi Akahoshi, Hiroaki Ono, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Middle-segment Preserving Pancreatectomy versus Total pancreatectomy: a comparative study of surgical and functional outcomes. The 35th Meeting of Japanese Society of Hepato-Billiary-Pancreatic Surgery 2023.07.01 Tokyo

Shotaro Gan, Daisuke Asano, Masaru Takeuchi, Masahiro Yamane, Akira Ito, Atsushi Nara, Koichiro Morimoto, Hironari Yamashita, Kohei Yagi, Shuichi Watanabe, Yoshiya Ishikawa, Hiroki Ueda, Hiroaki Ono, Keiichi Akahoshi, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. A case of unresectable pancreatic ductal adenocarcinoma (UR-PDAC) in an elderly patient who underwent radical resection after preoperative chemotherapy and survived without recurrence for 1 year. The 35th Meeting of Japanese Society of Hepato-Billiary-Pancreatic Surgery 2023.07.01 Tokyo

Hironari Yamashita, Hiroaki Ono, Daisuke Asano, Shuichi Watanabe, Yoshiya Ishikawa, Hiroki Ueda, Keiichi Akahoshi, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Proliferating cell nuclear antigen (PCNA) plays important role in malignancy of pancreatic cancer and might be the target protein of novel therapeutic drug. The 35th Meeting of Japanese Society of Hepato-Billiary-Pancreatic Surgery 2023.07.01 Tokyo

Hiroki Ueda, Atsushi Nara, Masaru Takeuchi, Masahiro Yamane, Akira Ito, Koichiro Morimoto, Hironari Yamashita, Kohei Yagi, Daisuke Asano, Yoshiya Ishiakwa, Shuichi Watanabe, Keiichi Akahoshi, Hiroaki Ono, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Age and Sarcopenia Are Risk Factors for ADL Decline After Pancreaticoduodenectomy; Our approach to maintain ADLs before and after surgery. The 35th Meeting of Japanese Society of Hepato-Billiary-Pancreatic Surgery 2023.07.01 Tokyo

Yoshiya Ishikawa, Yuzuki Sugiyama, Satoru Muro, Masahiro Yamane, Masaru Takeuchi, Daisuke Asano, Shuichi Watanabe, Hiroki Ueda, Keiichi Akahoshi, Hiroaki Ono, Atsushi Kudo, Shinji Tanaka, Keiichi Akita, Minoru Tanabe. Novel landmarks for the left posterior approach to the SMA based on the anatomical research. The 35th Meeting of Japanese Society of Hepato-Billiary-Pancreatic Surgery 2023.07.01 Tokyo

Koichiro Morimoto, Hiroki Ueda, Daisuke Asano, Shuichi Watanabe, Yoshiya Ishikawa, Keiichi Akahoshi, Shinji Tanaka, Minoru Tanabe. Characteristics of refractory postoperative cholangitis after hepatectomy with hepaticojejunostomy: Anastomotic stenosis is not the only cause. The 35th Meeting of Japanese Society of Hepato-Billiary-Pancreatic Surgery 2023.07.01 Tokyo

Daisuke Asano, Keiichi Akahoshi, Yoshiya Ishikawa, Shuichi Watanabe, Hiroki Ueda, Hiroaki Ono, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. How to achieve the negative surgical margin for ICC suspicious of invasion to hilum: with the video of laparoscopic left hepatectomy by hilar dissection approach. The 35th Meeting of Japanese Society of Hepato-Billiary-Pancreatic Surgery 2023.07.01 Tokyo

Shuichi Watanabe, Daisuke Asano, Yoshiya Ishikawa, Hiroki Ueda, Keiichi Akahoshi, Hiroaki Ono, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Investigation of recurrence format of single recurrent lesions using genomic analysis. The 35th Meeting of Japanese Society of Hepato-Billiary-Pancreatic Surgery 2023.07.01 Tokyo

Hiroaki Ono, Daisuke Asano, Shuichi Watanabe, Yoshiya Ishikawa, Hiroki Ueda, Keiichi Akahoshi, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Emerging Multidisciplinary Therapies Including PRRT Therapy in Pancreatic Neuroendocrine Neoplasms. The 35th Meeting of Japanese Society of Hepato-Billiary-Pancreatic Surgery 2023.07.01 Tokyo

Akira Ito, Keiichi Akahoshi, Masaru Takeuchi, Masahiro Yamane, Shotaro Gan, Atsushi Nara, Koichiro Morimoto, Munetaka Kimura, Hironari Yamashita, Kohei Yagi, Daisuke Asano, Yoshiya Ishikawa, Shuichi Watanabe, Hiroki Ueda, Hiroaki Ono, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Hepatectomy After Pancreatoduodenectomy Has a High Risk of Postoperative Complications. The 35th Meeting of Japanese Society of Hepato-Billiary-Pancreatic Surgery 2023.06.30 Tokyo

Shinji Tanaka. Educational Session：New currents in the field of HBP surgery. The 35th Meeting of Japanese Society of Hepato-Billiary-Pancreatic Surgery 2023.06.30 Tokyo

Atsushi Nara, Keiichi Akahoshi, Akira Ito, Shotaro Gan, Daisuke Asano, Shuichi Watanabe, Yoshiya Ishikawa, Hiroki Ueda, Hiroaki Ono, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Pancreatic duct stent AMY after pancreaticoduodenectomy is a predictor of pancreatic fistula. The 35th Meeting of Japanese Society of Hepato-Billiary-Pancreatic Surgery 2023.06.30 Tokyo

Shu Tsukihara, Yoshimitsu Akiyama, Shu Shimada, Megumi Hatano, Yusuke Kinugasa, Ken Eto, Shinji Tanaka. Histone H3 lysin 9 methyltransferase SETDB1 promotes gastric carcinogenesis by multiple signaling pathways. Digestive Disease Week 2023 2023.05.10 Chicago

A.Nara, K.Akahoshi, H.Ueda, D.Asano, S.Watanabe, Y.Ishikawa, H.Ono, A.Kudo, S.Tanaka, M.Tanabe. Usefulness of the NRSS in Determining the Timing of TAE for Ruptured Hepatocellular Carcinoma. 18th Annual Academic Surgical Congress 2023.02.08 Houston

Keiichi Akahoshi, Yoshiya Ishikawa, Daisuke Asano, Hiroki Ueda, Kosuke Ogawa, Hiroaki Ono, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Safety methods to perform laparoscopic liver resection for liber cirrhosis. ACRLS 2022 2022.12.09 Nagoya

Shinji Tanaka. Surgical oncology to elucidate molecular and immunological mechanisms for clinical application in hepato-biliary-pancreatic cancer (lecture). UCh-TMDU Joint Symposium 2022.11.08 Chile（on-line）

Atsushi Nara, Keiichi Akahoshi, Hiroki Ueda, Koichiro Morimoto, Masaru Takeuchi, Masahiro Yamane, Akira Ito, Shotaro Gan, Munetaka Kimura, Hironari Yamashita, Kohei Yagi, Daisuke Asano, Shuichi Watanabe, Yoshiya Isikawa, Hiroaki Ono, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Usefulness of the Novel Rupture Severity Score (NRSS) in Determining the Timing of Transarterial Embolization (TAE) for Ruptured Hepatocellular Carcinoma. IASGO-CME 2022.10.26 Fukuoka

田中 真二. がんの進展・浸潤に関与する新たな分子生物学的マーカーの開発　外科臨床に基づく難治性がんの分子免疫機序と治療戦略. 日本癌治療学会学術集会抄録集 2022.10.01

Shinji Tanaka. Workshop 9：Molecular mechanisms of liver cancer (including HCC, CCC, metastatic liver cancer) , Molecular and immunological mechanisms of liver cancer; preclinical studies for clinical application (invited lecture). APASL Oncology 2022 2022.09.01 Takamatsu (on-line)

島田 周, 秋山 好光, 田中 真二. CRISPR/Cas9システムを用いたエクソンスキッピングによるβ-cateninシグナルの内在性活性化が肝がん細胞の免疫回避に寄与する(Intrinsic activation of β-catenin signaling by CRISPR/Cas9-mediated exon skipping contributes to immune evasion in HCC). 日本癌学会総会記事 2022.09.01

Ono Hiroaki, Murase Yoshiki, Asano Daisuke, Watanabe Syuuichi, Ishikawa Yoshiya, Ueda Hiroki, Akahoshi Keiichi, Kudo Atsushi, Tanaka Shinji, Tanabe Minoru. Basic & translational researches on PanNEN: bench to bedside　Evaluation of the efficacy of Ispinesib, a novel Eg 5 inhibitor, for the treatment of high grade Pan-NENs(タイトル和訳中). 膵臓 2022.09.01

Hiroaki Ono, Yoshiki Murase, Daisuke Asano, Syuuichi Watanabe, Yoshiya Ishikawa, Hiroki Ueda, Keiichi Akahoshi, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Evaluation of the efficacy of Ispinesib, a novel Eg5 inhibitor, for the treatment of high grade Pan-NENs. Joint Congress of the 26th Meeting of IAP and the 53rd Annual Meeting of JPS 2022.07.08 Kyoto

Yoshiya Ishikawa, Daisuke Asano, Shuichi Watanabe, Hiroki Ueda, Keiichi Akahoshi, Hiroaki Ono, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Safe approach to dissect hepatoduodenal ligament during laparoscopic pancreaticoduodenectomy. The 34th Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2022.06.11 Ehime

Aya Maekawa, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Hormonaltumor mapping for liver metastases of gastroenteropancreatic neuroendocrine neoplasms. The 34th Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2022.06.11 Ehime

Daisuke Asano, Yoshiya Ishikawa, Shuichi Watanabe, Hiroki Ueda, Keiichi Akahoshi, Hiroaki Ono, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. The novel techniques of distal pancreatectomy using articulation forceps -introducing the desterity of a robotic system to a palaroscopic surgery. The 34th Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2022.06.11 Ehime

Daisuke Asano, Atushi Kudo, Yoshiya Ishikawa, Shuichi Watanabe, Hiroki Ueda, Keiichi Akahoshi, Hiroaki Ono, Shinji Tanaka, Minoru Tanabe. Reappraisal of surgical treatment for liver metastases of neuroendocrine neoplasms. The 34th Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2022.06.11 Ehime

Shotaro Gan, Hiroki Ueda, Atsushi Nara, Akira Ito, Koichiro Morimoto, Hironari Yamashita, Munetaka Kimura, Kohei Yagi, Takeshi Ishii, Daisuke Asano, Shuichi Watanabe, Yoshiya Ishikawa, Keiichi Akahoshi, Hiroaki Ono, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Discussion on the treatment of liver cysts at our hospital. The 34th Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2022.06.11 Ehime

Akira Ito, Daisuke Asano, Shotaro Gan, Atsushi Nara, Koichiro Morimoto, Munetaka Kimura, Hironari Yamashita, Kohei Yagi, Takeshi Ishii, Yoshiya. Strategy of pancreatic ductal adenocarcinoma treatment. The 34th Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2022.06.11 Ehime

Akira Ito, Daisuke Asano, Shotaro Gan, Atsushi Nara, Koichiro Morimoto, Munetaka Kimura, Hironari Yamashita, Kohei Yagi, Takeshi Ishii, Yoshiya Ishikawa, Shuichi Watanabe, Hiroki Ueda, Keiichi Akahoshi, Hiroaki Ono, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe . Strategy of pancreatic ductal adenocarcinoma treatment. The 34th Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2022.06.11 Ehime

Hiroaki Ono, Daisuke Asano, Shuichi Watanabe, Yoshiya Ishikawa, Hiroki Ueda, Keiichi Akahoshi, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Validation of surgical resection for pancreatic neuroendocrine neoplasms with simulataneous liver metastases. The 34th Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2022.06.10 Ehime

Keiichi Akahoshi, Akira Ito, Atsushi Nara, Shotaro Gan, Takeshi Ishii, Kohei Yagi, Koichiro Morimoto, Hironari Yamashita, Munetaka Kimura, Daisuke Asano, Shuichi Watanabe, Yoshiya Ishikawa, Hiroki Ueda, Hiroaki Ono, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Transpapillary or transmural drainage for postoperative pancreatic fistula after distal pancreatectomy. The 34th Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2022.06.10 Ehime

Hiroki Ueda, Daisuke Asano, Shuichi Watanabe, Yoshiya Ishikawa, Keiichi Akahoshi, Hiroaki Ono, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Clinical features of malignant insulinoma from single center experience. The 34th Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2022.06.10 Ehime

Atsushi Nara, Hiroki Ueda, Yukue Shimizu, Daisuke Asano, Yoshiya Ishikawa, Shuichi Watanabe, Keiichi Akahoshi, Hiroaki Ono, Shinji Tanaka, Minoru Tanabe. Evaluation of sarcopenia using preoperative InBody and short-term results after pancreaticoduodenectomy. The 34th Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2022.06.10 Ehime

Hiroki Ueda, Daisuke Asano, Shuichi Watanabe, Yoshiya Ishikawa, Keiichi Akahoshi, Hiroaki Ono, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Clinical features of malignant insulinoma from single center experience. The 34th Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2022.06.10

Koichiro Morimoto, Hiroki Ueda, Daisuke Asano, Yoshiya Ishikawa, Syuichi Watanebe, Keiichi Akahoshi, Hiroaki Ono, Atushi Kudo, Shinji Tanaka, Minoru Tanabe. Risk factors of postoperative cholangitis after hepatectomy with hepato-jejunostomy for malignancy-Clumping test predicts late refractory cholangitis. The 34th Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2022.06.10 Ehime

Kohei Yagi, Hiroaki Ono, Atsushi Kudo, Akira Ito, Atsushi Nara, Syotaro Gan, Munetaka Kimura, Hironari Yamashita, Takeshi Ishii, Daisuke Aasano, Syuichi Watanabe, Hiroki Ueda, Yoshiya Ishikawa, Keiichi Akahoshi, Shinji Tanaka, Minoru Tanabe. Significance of MGMT expression for streptozocin treatment of pancreatic neuroendocrine neoplasms. The 34th Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2022.06.10 Ehime

Hironari Yamashita, Keiichi Akahoshi, Akira Ito, Shoutaro Gan, Atsushi Nara, Munetaka Kimura, Koichiro Morimoto, Kouhei Yagi, Takeshi Ishi, Daisuke Asano, Yoshiya Ishikawa, Shuichi Watanabe, Hiroki Ueda, Hiroaki Ono, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Clinical outcome of pT1 pancreatic ductal adenocarcinoma-what is the risk factor of poor prognosis？. The 34th Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2022.06.10 Ehime

Takeshi Ishii, Keiichi Akahoshi, Koichirou Morimoto, Hironari Yamashita, Kouhei Yagi, Daisuke Asano, Yoshiya Ishikawa, Hiroki Ueda, Hiroaki Ono, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. A single-center retrospective study of 17 cases of pancreatic metastasis from renal cell carcinoma. The 34th Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2022.06.10

Shinji Tanaka. Workshop 2: Innovative research of biomarkers for HBP cancers, Biomarker research and clinical application for treatment of hepato-biliary-pancreatic cancer　(invited lecture). The 34th Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2022.06.10 Matsuyama (on-line)

Yamashita Hironari, Akahoshi Keiichi, Ito Akira, Gan Shoutaro, Nara Atsushi, Kimura Munetaka, Morimoto Koichiro, Yagi Kouhei, Ishi Takeshi, Asano Daisuke, Ishikawa Yoshiya, Watanabe Shuichi, Ueda Hiroki, Ono Hiroaki, Kudo Atsushi, Tanaka Shinji, Tanabe Minoru. pT1膵管腺癌の臨床転帰　予後不良の危険因子は何か?(Clinical outcome of pT1 pancreatic ductal adenocarcinoma: what is the risk factor of poor prognosis?). 日本肝胆膵外科学会・学術集会プログラム・抄録集 2022.06.01

Nara Atsushi, Ueda Hiroki, Shimizu Yukue, Asano Daisuke, Ishikawa Yoshiya, Watanabe Shuichi, Akahoshi Keiichi, Ono Hiroaki, Tanaka Shinji, Tanabe Minoru. InBodyを用いたサルコペニアの術前評価と膵頭十二指腸切除術後の短期成績(Evaluation of sarcopenia using preoperative InBody and short-term results after pancreaticoduodenectomy). 日本肝胆膵外科学会・学術集会プログラム・抄録集 2022.06.01

Asano Daisuke, Ishikawa Yoshiya, Watanabe Shuichi, Ueda Hiroki, Akahoshi Keiichi, Ono Hiroaki, Kudo Atsushi, Tanaka Shinji, Tanabe Minoru. 多自由度鉗子を用いた膵体尾部切除術の新しい手技　腹腔鏡手術にロボットシステムの器用さを導入するために(The novel techniques of distal pancreatectomy using articulating forceps～introducing the dexterity of a robotic system to a laparoscopic surgery). 日本肝胆膵外科学会・学術集会プログラム・抄録集 2022.06.01

Shinji Tanaka. Invited Lecture; Stemness and heterogeneity of liver cancer. JSH International Liver Conference 2021 2021.10.02 Hakata International Exhibition Hall & Conference Center, Fukuoka （on-line）

小野 宏晃, 赤星 径一, 田中 真二, 田邉 稔. RRM1は膵臓癌細胞の細胞外マトリックスタンパク質を転換し悪性化形質獲得に寄与している. 日本癌学会総会記事 2021.09.01

田中 真二. 外科腫瘍学に基づいた肝胆膵癌に対する新規分子標的-免疫併用療法の開発. 日本癌学会総会記事 2021.09.01

Kohei Yagi, Hiroki Ueda, Koichiro Morimoto, Hironari Yamashita, Yoshiki Murase, Aya Maekawa, Takeshi Ishii, Toshitaka Sugawara, Shuichi Watanabe, Yoshiya Ishikawa, Keiichi Akashoshi, Kosuke Ogawa, Hiroaki Ono, Atsushi Kudo, SHinji Tanaka, Minoru Tanabe. A review of resected cases of primary duodenal cancer in our hospital. The 33rd Meeting of Japanese Society of Hepato-Billiary-Pancreatic Surgery 2021.06.02 Osaka

Hiroyuki Ishida, Hiroki Ueda, Keiichi Akahoshi, Yoshiya Ishikawa, Hironari Yamashita, Koichiro Morimoto, Kosuke Ogawa, Hiroaki Ono, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Early recurrence after curative hepatectomy for colorectal liver metastases. The 33rd Meeting of Japanese Society of Hepato-Billiary-Pancreatic Surgery 2021.06.02 Osaka

Keiichi Akahoshi, Yoshiya Ishikawa, Hiroki Ueda, Kosuke Ogawa, Hiroaki Ono, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Conversion surgery after lenvatinib treatment for advanced hepatocellular carcinoma. The 33rd Meeting of Japanese Society of Hepato-Billiary-Pancreatic Surgery 2021.06.02 Osaka

Aya Maekawa, Keiichi Akahoshi, Yoshiya Ishikawa, Hiroki Ueda, Kosuke Ogawa, Hiroaki Ono, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Validation of the international consensus guideline 2017 for intraductal papillary mucinous neoplasms. The 33rd Meeting of Japanese Society of Hepato-Billiary-Pancreatic Surgery 2021.06.02 Osaka

Yoshiki Murase, Hiroaki Ono, Risa Yoshioka, Yoshiya Ishikawa, Hiroki Ueda, Keiichi Akahoshi, Kosuke Ogawa, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. High Eg5 expression predicts poor prognosis in pancreatic cancer. The 33rd Meeting of Japanese Society of Hepato-Billiary-Pancreatic Surgery 2021.06.02 Osaka

Yoshiya Ishikawa, Hiroyuki Ishida, Koichiro Morimoto, Hironari Yamashita, Hiroki Ueda, Keiichi Akahoshi, Kosuke Ogawa, Hiroaki Ono, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Laparoscopic distal pancreatectomy for pancreatic ductal adenocarcinoma using supracolic anterior approach to the superior mesenteric artery. The 33rd Meeting of Japanese Society of Hepato-Billiary-Pancreatic Surgery 2021.06.02 Osaka

Hironari Yamashita, Keiichi Akahoshi, Koichirou Morimoto, Hiroyuki Ishida, Kohei Yagi, Aya Maekawa, Yoshiki Murase, Takeshi Ishii, Toshitaka Sugawara, Yoshiya Ishikawa, Hiroki Ueda, Kosuke Ogawa, Hiroaki Ono, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Effect of neoadjuvant chemotherapy on short-term outcome in patients undergoing pancreaticoduodenectomy for borderline resectable pancreatic cancer and resectable pancreatic cancer with elevated serum tumor markers. The 33rd Meeting of Japanese Society of Hepato-Billiary-Pancreatic Surgery 2021.06.02 Osaka

Hiroaki Ono, Atsushi Kudo, Yoshiya Ishikawa, Hiroki Ueda, Keiichi Akahoshi, Kosuke Ogawa, Shinji Tanaka, Minoru Tanabe. Combination of Weekly Streptozocin and Oral S-1 Treatment is effective treatment for unresectable or metastatic pancreatic NET-G1 and NET-G2 patients. The 33rd Meeting of Japanese Society of Hepato-Billiary-Pancreatic Surgery 2021.06.02 Osaka

Hiroki Ueda, Koichiro Morimoto, Hironari Yamashita, Hiroyuki Ishida, Kohei Yagi, Aya Maekawa, Yoshiki Murase, Toshitaka Sugawara, Takeshi Ishii, Yoshiya Ishikawa, Keiichi Akahoshi, Kosuke Ogawa, Hiroaki Ono, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Perioperative outcomes in elderly patients over 75-years-old undergoing distal pancreatectomy. The 33rd Meeting of Japanese Society of Hepato-Billiary-Pancreatic Surgery 2021.06.02 Osaka

Koichiro Morimoto, Keiichi Akahoshi, Hironari Yamashita, Hiroyuki Ishida, Kohei Yagi, Aya Maekawa, Yoshiki Murase, Takeshi Ishii, Toshitaka Sugawara, Yoshiya Ishikawa, Hiroki Ueda, Kosuke Ogawa, Hiroaki Ono, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Granulomatous Langerhans isletitis followed by nivolumab-induced type 1 diabetes mellitus in a distal pancreatectomy: case report. The 33rd Meeting of Japanese Society of Hepato-Billiary-Pancreatic Surgery 2021.06.02 Osaka

Takeshi Ishii, Atsushi Kudo, Yoshiki Murase, Aya Maekawa, Toshitaka Sugawara, Yoshiya Ishikawa, Shuichi Watanabe, Hiroki Ueda, Keiichi Akahoshi, Kousuke Ogawa, Hiroaki Ono, Shinji Tanaka, Minoru Tanabe. The management of GEP-NET with MEN type 1 in our department. The 33rd Meeting of Japanese Society of Hepato-Billiary-Pancreatic Surgery 2021.06.02 Osaka

Ueda Hiroki, Morimoto Koichiro, Yamashita Hironari, Ishida Hiroyuki, Yagi Kohei, Maekawa Aya, Murase Yoshiki, Sugawara Toshitaka, Ishii Takeshi, Ishikawa Yoshiya, Akahoshi Keiichi, Ogawa Kosuke, Ono Hiroaki, Kudo Atsushi, Tanaka Shinji, Tanabe Minoru. 75歳以上の高齢患者に対する膵体尾部切除術の周術期成績(Perioperative outcomes in elderly patients over 75-years-old undergoing distal pancreatectomy). 日本肝胆膵外科学会・学術集会プログラム・抄録集 2021.06.01

Ishii Takeshi, Kudo Atsushi, Murase Yoshiki, Maekawa Aya, Sugawara Toshitaka, Ishikawa Yoshiya, Watagebe Shuichi, Ueda Hiroki, Akahoshi Keiichi, Ogawa Kousuke, Ono Hiroaki, Tanaka Shinji, Tanabe Minoru. MEN type 1を伴うGEP-NETの管理(The management of GEP-NET with MEN type1 in our department). 日本肝胆膵外科学会・学術集会プログラム・抄録集 2021.06.01

Maekawa Aya, Akahoshi Keiichi, Ishikawa Yoshiya, Ueda Hiroki, Ogawa Kosuke, Ono Hiroaki, Kudo Atsushi, Tanaka Shinji, Tanabe Minoru. IPMN国際診療ガイドライン2017年版の検証(Validation of the international consensus guideline 2017 for intraductal papillary mucinous neoplasms). 日本肝胆膵外科学会・学術集会プログラム・抄録集 2021.06.01

Tomotaka Kato, Yoshiya Ishikawa, Shuichi Watanabe, Keiichi Akahoshi, Kosuke Ogawa, Hiroaki Ono, Daisuke Ban, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Comparison of open and laparoscopic hepatectomy for obese patients with HCC. The 33rd Annual Meeting of the Japan Society for Endoscopic Surgery 2021.03.10 Web

Takeshi Ishii, Keiichi Akahoshi, Kohei Yagi, Aya Maekawa, Yoshiki Murase, Toshitaka Sugawara, Masafumi Akasu, Tomotaka, Kato, Yoshiya Ishikawa, Shuichi Watanabe, Kousuke Ogawa, Hiroaki Ono, Daisuke Ban, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Clinical Analysis of 23 Cases of total pancreatectomy in Tokyo Medical and Dental University. The 32nd Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2021.02.23 Web

Keiichi Akahoshi, Kohei Yagi, Yoshiki Murase, Takeshi Ishii, Toshitaka Sugawara, Yoshiya Ishikawa, Shuichi Watanabe, Kosuke Ogawa, Hiroaki Ono, Daisuke Ban, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Non-viral hepatocellular carcinoma and, diabetes and obesity as its risk factorslar carcinoma and, diabetes and obesity as its risk factors. The 32nd Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2021.02.23 Web

Kohei Yagi, Atsushi Kudo, Aya Maekawa, Yoshiki Murase,　Takeshi　Ishii,　Tomotaka　Kato,　Masafumi　Akasu,　Toshitaka　Sugawara,　Yoshiya　Ishikawa,　Shuichi Watanabe, Keiichi Akahoshi, Ogawa Kosuke, Hiroaki Ono, Daisuke Ban, Shinji Tanaka, Minoru Tanabe. Evaluation of laparoscopic distal pancreatectomy for pancreatic neuroendocrine tumors. The 32nd Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2021.02.23 Web

Keiichi Akahoshi, Yoshiya Ishikawa, Hiroki Ueda, Kosuke Ogawa, Hiroaki Ono, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Liver resection after systemic chemotherapy improved overallsurvival of metastatic neuroendocrine neoplasms. The 32nd Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2021.02.23 Web

Shuichi Watanabe, Shu Shimada, Jo NIshino, Kohei Yagi, Aya Maekawa, Yoshiki Murase, Toshitaka Sugawara, Takeshi Ishii, Tomotaka Kato, Masafumi Akasu, Yoshiya Ishikawa, Keiichi Akahoshi, Kosuke Ogawa, Hiroaki Ono, Daisuke Ban, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Estimation of the type of HCC metastasis based on the multicellular colonization model. The 32nd Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2021.02.23 Web

Hiroaki Ono, Tomotaka Kato, Aya Maekawa, Kouhei Yagi, Yoshiya Ishikawa, SHuichi Watanabe, Keiichi Akahoshi, Kousuke Ogawa, Daisuke Ban, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Cytoplasmic RRM1 activation in acute phase of gemcitabine treatment is involved in acquired resistance of pancreatic cancer. The 32nd Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2021.02.23 Web

藤田 征志, 山口 類, 有廣 光司, 島田 周, 宮野 悟, 山上 裕機, 茶山 一彰, 垣見 和宏, 田中 真二, 井元 清哉, 中川 英刀. がん免疫ゲノム解析　肝臓がんの免疫ゲノム解析. 日本癌学会総会記事 2020.10.01

Tanaka Shinji, Watanabe Shuichi, Tanabe Minoru. バイオマーカー、遺伝子解析の消化器がん診断・治療への応用　サブタイプ特異的オーダーメイド免疫療法のための肝細胞癌の新しい遺伝的および免疫学的分類(Application of biomarker and genetic tests for diagnosis and treatment of gastrointestinal cancers　Novel genetic and immunological classification of hepatocellular carcinoma for the subtype-specific precision immunotherapy). 日本消化器病学会雑誌 2019.11.01

藤田 征志, 山口 類, 有廣 光司, 島田 周, 宮野 悟, 山上 裕機, 茶山 一彰, 垣見 和宏, 田中 真二, 井元 清哉, 中川 英刀. イムノゲノミクスの進歩と精密医療への応用　肝臓がん免疫抑制機構の免疫ゲノム解析(Advances in immunogenomics and application to precision medicine　Immunogenomic analysis of immune suppression mechanisms in primary liver cancer). 日本癌学会総会記事 2019.09.01

Toshitaka Sugawara,Daisuke Ban,Takeshi Ishii,Satoshi Matsui,Masahumi Akasu,Tomotaka Kato,Daisuke Asano,Jun Yoshino,Shuichi Watanabe, Toshiro Ogura,Kosuke Ogawa, Hiroaki Ono,Yusuke Mitsunori,Atsushi Kudo,Shinji Tanaka,Minoru Tanabe. Preoperative factors for early recurrence of resected pancreatic ductal adenocarcinoma. The 31st Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2019.06.14 Takamatsu

Shuichi Watanabe, Daisuke Ban,Toshiro Ogura,Kosuke Ogawa, Hiroaki Ono,Yusuke Mitsunori,Atsushi Kudo,Shinji Tanaka,Minoru Tanabe. The analysis of the treatment for the metachronous solitary metastasis after curative surgery in pancreatic cancer. The 31st Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2019.06.14 Takamatsu

Takeshi Ishii,Toshiro Ogura,Yoshiki Murase,Toshitaka Sugawara,Masahumi Akasu, Tomotaka Kato,Jun Yoshino,Shuichi Watanabe, Kosuke Ogawa, Hiroaki Ono,Yusuke Mitsunori,Daisuke Ban,Atsushi Kudo,Shinji Tanaka,Minoru Tanabe. Surgery for obese patients with hepatocellular carcinoma. The 31st Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2019.06.13 Takamatsu

Yuki Mizuno, Shu Shimada, Yoshimitsu Akiyama, Shuichi Watanabe,Tomomi Aida, Kosuke Ogawa、Hiroaki Ono, Yusuke　Mitsunori、Daisuke Ban, Atsushi Kudo, Shoji Yamaoka, Shinji Tanaka, Minoru Tanabe. DEPDC5 deficiency contributes to resistance to leucine starvation via p62 accumulation in hepatocellular carcinoma. Yuki Mizuno, Shu Shimada, Yoshimitsu Akiyama, Shuichi Watanabe,Tomomi Aida, Kosuke Ogawa、Hiroaki Ono, Yusuke　Mitsunori、Daisuke Ban, Atsushi Kudo, Shoji Yamaoka, Shinji Tanaka, Minoru Tanabe 2018.09.28 Osaka

渡辺 雄一郎, 本田 真也, 小西 昭充, 田邉 稔, 田中 真二, 清水 重臣. オートファジーはCep63を介して中心体数を制御する(Autophagy controls centrosome number by degrading Cep63). 日本癌学会総会記事 2018.09.01

深町 博史, 西川路 武人, 島田 周, 秋山 好光, 湯浅 保仁, 土屋 輝一郎, 田中 真二. 低分化型胃がんは、形成過程の異なる2つのクラスターに分類できる(Diffuse-type gastric cancers are classified into two clusters, which may be formed via different carcinogenic pathways). 日本癌学会総会記事 2018.09.01

島田 周, 秋山 好光, 田邉 稔, 田中 真二. メタボリック関連肝癌の腫瘍内星細胞におけるFABP4発現亢進の意義(FABP4 overexpression in intratumoral hepatic stellate cells within hepatocellular carcinoma with metabolic risk factors). 日本癌学会総会記事 2018.09.01

田中 真二. プレシジョンメディシン時代の分子標的治療　プレシジョンメディシン時代の肝癌分子標的治療(Molecular target therapy under precision medicine　Molecular target therapy for liver cancer under precision medicine). 日本癌学会総会記事 2018.09.01

Shuichi Watanabe、Shu Shimada、Yoshimitsu Akiyama、Kosuke Ogawa、Hiroaki Ono、Yusuke Mitsunori、Daisuke Ban、Atsushi Kudo、Minoru Tanabe、Shinji Tanaka. Precision medicine for the poorest prognosis subtype of pancreatic cancer. The 73rd General Meeting of the Japanese Society of Gastroenterological Surgery 2018.07.12 Kagoshima

Tomotaka Kato、Daisuke Ban、Keiichi Akahoshi、Toshiro　Ogura、Kosuke Ogawa、Hiroaki　Ono、Yusuke　Mitsunori、Atsushi　Kudo、Shinji　Tanaka、 Minoru Tanabe . Treatment strategies of resectable pancreatic cancer with hazy density around major artery. The 73rd General Meeting of the Japanese Society of Gastroenterological Surgery 2018.07.12 Kagoshima

Yusuke Mitsunori,Masafumi Akasu,Tomotaka Kato,Jun Yoshino, Shuichi Watanabe,Norimichi　Chiyonobu,Keiichi Akahoshi,Toshiro Ogura,Kosuke Ogawa, Hiroaki Ono, Daisuke Ban, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. What is predictive factor of postoperative diabetes mellitus in patients with distal pancreatectomy？. The 30th Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2018.06.09 yokohama

Toshiro Ogura, Tomotaka Kato, Masafumi Akasu, Jun Yoshino, Shuichi Watanabe, Norimichi Chiyonobu, Yuki Mizuno, Keiichi Akahoshi, Kosuke Ogawa, Hiroaki Ono, Yusuke Mitsunori,Daisuke Ban, Atsushi Kudo,Shinji Tanaka, Minoru Tanabe. The implication of lymph node metastasis on survival in cases with distal pancreatic cancer. The 30th Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2018.06.09

Shuichi Watanabe, Atsushi Kudo, Masafumi Akasu, Tomotaka Kato, Jun Yoshino, Norimichi Chiyonobu, Yuki Mizuno, Keiichi Akahoshi, Kosuke Ogawa, Toshiro Ogura, Yusuke Mitsunori, Hiroaki Ono, Daisuke Ban, Shinji Tanaka, Minoru Tanabe. The efficacy of liver SASI test for the the advanced functional PNET patients. The 30th Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2018.06.09 yokohama

Jun Yoshino,Toshiro Ogura,Keiichi Akahoshi,Kosuke Ogawa, Yusuke Mitsunori,Hiroaki Ono, Daisuke Ban, Atsushi Kudo, Shinji Tanaka, Minoru Tanabe. Long-term outcomes and prognostic factors of patients with gallbladder cancer resection. The 30th Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery 2018.06.08

Akasu Masafumi, Kudo Atsushi, Kato Tomotaka, Yoshino Jun, Watanabe Shuichi, Chiyonobu Norimichi, Mizuno Yuki, Akahoshi Keichi, Ogura Toshiro, Ogawa Kosuke, Ono Hiroaki, Mitsunori Yusuke, Ban Daisuke, Tanaka Shinji, Tanabe Minoru. P-NETに対する分子標的薬の治療成績(The results of molecular targeted drugs to P-NET). 日本肝胆膵外科学会・学術集会プログラム・抄録集 2018.06.01

Tomotaka Kato,Atsushi Kudo, Hiroaki Ono, Masahumi Akasu, Jun Yoshino, Kosuke Ogawa, Toshiro Ogura , Yusuke Mitsunori, Daisuke Ban, Shinji Tanaka,Minoru Tanabe. A Surgical Case of Spontaneous and Asymptomatic Intrahepatic Hemorrhage with HCC. APASL2018 2018.05.12 Yokohama

Minoru Tanabe, Toshiro Ogura, Atsushi Kudo, Daisuke Ban, Shinji Tanaka. Surgery for Obese Patients with HCC. APASL2018 2018.05.12 Yokohama

深町 博史, 西川路 武人, 島田 周, 秋山 好光, 湯浅 保仁, 土屋 輝一郎, 田中 真二. 低分化型胃がん幹細胞の増殖制御機構　患者由来がん幹細胞の初代培養系を用いた同定. 日本癌学会総会記事 2017.09.01

Watanabe Shuichi, Ban Daisuke, Iwao Yasuhito, Akahoshi Keiichi, Ono Akihiro, Mitsunori Yusuke, Matsumura Satoshi, Ochiai Takanori, Kudo Atsushi, Tanaka Shinji, Tanabe Minoru. 再発性膵癌の予後の研究　孤立性再発の意義(Study of the prognosis of recurrent pancreatic cancer: The significance of the solitary recurrence). Journal of Hepato-Biliary-Pancreatic Sciences 2017.05.01

Kudo Atsushi, Ban Daisuke, Akahoshi Keiichi, Mitsunori Yusuke, Tanaka Shinji, Tanabe Minoru. 切除不能または転移性の膵神経内分泌腫瘍を有する患者では全身療法により手術適応が決まる可能性がある(Systemic therapy may decide surgical indication for patients with Unresectable or Metastatic Pancreatic Neuroendocrine Tumor). Journal of Hepato-Biliary-Pancreatic Sciences 2017.05.01

田中 真二, 島田 周, 秋山 好光, 松村 聡, 光法 雄介, 藍原 有弘, 落合 高徳, 伴 大輔, 工藤 篤, 有井 滋樹, 田邉 稔. Precision medicine　bench to bedside　肝胆膵がんの分子サブタイプと治療抵抗性解析によるprecision medicineの展開. 日本外科学会定期学術集会抄録集 2017.04.01

Ochiai T, Asano D, Yoshino J, Watanabe S, Ishikawa Y, Chiyonobu N, Mizuno Y, Sato T, Ueda H, Iwao Y, Ono H, Mitsunori Y, Matsumura S, Ban D, Kudo A, Tanaka S, Tanabe M. 07.03 Surgical Strategy of Hepatic Resection with Inferior Vena Cava Resection for Liver Cancers. 12th Annual Academic Surgical Congress 2017.02.07

Tanaka S, Ogawa K, Matsumura S, Aihara A, Ban D, Ochiai T, Irie T, Kudo A, Arii S, Tanabe M. A preclinical study of EpCAM-targeted therapy for human hepatocellular carcinoma with stem cell features. 65th Annual Meeting of the American Association for the Study of Liver diseases 2014.11.10 Boston, USA

Katsuta E, Kudo A, Ohata Y, Ueda H, Sato A, Oba A, Akahoshi K, Nakao K, Furuyama T,Ito H, Matsumura S, Aihara A, Ban D, Ochiai T, Irie T, Tanaka S, Tanabe M. Morphology of pancreatic Neuroendocrine Tumor (P-NET). American Pancreatic Association 2014.11.09 Waimea, Hawaii, USA

Ueda H, Ban D, Ohata Y, Sato T, Ohba A, Akahoshi K, Furuyama T, Ito H, Nakao K, Katsuta E, Matsumura S, Mitsunori Y, Aihara A, Ochiai T, Kudo A, Tanaka S, Tanabe M. The optimal dividing line of the jejunum for pancreatoduodenectomy. The Scientific Meeting of Japan-Hungary-Poland Surgical Society [Triangle Symposium 2014] 2014.10.18 Tokyo

Tanaka S. “Novel molecular targets and therapeutic combinations in hepatocellular carcinoma; rationale and significance” (invited lecture). 4th International Kyoto Liver Cancer Symposium 2014.06.08 Kyoto

Tanaka S, Ogawa K, Murakata A, Mogushi K, Matsumura S, Aihara A, Ban D, Ochiai T, Irie T, Kudo A, Nakamura N, Tanaka H, Arii S, Tanabe M. Preclinical studies of EpCAM-targeted therapy for human hepatocellular carcinoma with specific inhibition of stem cell features. 105th Annual Meeting of the American Association for Cancer Research 2014.04.06 San Diego, USA

Ochiai T, Shioya A, Honma H, Saitoh Y, Matsumura S, Ban D, Irie T, Kudo A, Nakamura N, Fujikawa T, Itai A, Tanaka S, Arii S, Yamaoka S, Tanabe M. Combination treatment of IκB kinase β inhibitor IMD-0354 and gemcitabine suppresses oncogenic proliferation of pancreatic cancer cells. 9th Annual Academic Surgical Congress 2014.02.04 San Diego, USA