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ITO Nobutoshi
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Graduating School 【 display / non-display 】
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The University of Tokyo, Faculty of Engineering, 1986.03, Graduated
Graduate School 【 display / non-display 】
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The University of Tokyo, Graduate School, Division of Engineering, Master's Course, 1988.03, Completed
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The University of Leeds, Department of Biochemistry & Molecular Biology, Doctor's Course, 1991.08, Completed
Campus Career 【 display / non-display 】
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2012.04-NowTokyo Medical and Dental University, Medical Research Institute, Advanced Molecular Medicine, Structural Biology, Professor
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2012.04-NowTokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Life Science and Technology, Life Science and Technology, Structural Biology, Professor
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2003.04-2012.03Tokyo Medical and Dental University, Biomedical Science PhD Program / Graduate School of Biomedical Science, Professor
External Career 【 display / non-display 】
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1991.08-1992.06The University of Leeds, Dept of Biochem. & Mol. Biol., Research Fellow
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1992.07-1994.11MRC Laboratory of Molecular Biology, Scientific Staff
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1994.12-1996.05The University of Leeds, Dept of Biochem. & Mol. Biol., Research Fellow
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1996.06-2001.07Biomolecular Engineering Research Institute,
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2001.08-2003.03Japan Science and Technology Agency,
Academic Society Affiliations 【 display / non-display 】
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The Biophysical Society of Japan
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Japanese Society for Chemical Biology
Research Areas 【 display / non-display 】
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Structural biochemistry
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Biophysics
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Chemical biology
Published Papers & Misc 【 display / non-display 】
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Alborzian Deh Sheikh A, Gomaa S, Li X, Routledge M, Saigoh K, Numoto N, Angata T, Hitomi Y, Takematsu H, Tsuiji M, Ito N, Kusunoki S, Tsubata T. A Guillain-Barré syndrome-associated SIGLEC10 rare variant impairs its recognition of gangliosides. Journal of autoimmunity. 2021.01; 116 102571. ( PubMed, DOI )
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Sasaki H, Masuno H, Kawasaki H, Yoshihara A, Numoto N, Ito N, Ishida H, Yamamoto K, Hirata N, Kanda Y, Kawachi E, Kagechika H, Tanatani A. Lithocholic Acid Derivatives as Potent Vitamin D Receptor Agonists. Journal of medicinal chemistry. 2020.12; ( PubMed, DOI )
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Emori Miho, Numoto Nobutaka, Senga Akane, Bekker Gert-Jan, Kamiya Narutoshi, Kobayashi Yuma, Ito Nobutoshi, Kawai Fusako, Oda Masayuki. Structural basis of mutants of PET-degrading enzyme from Saccharomonospora viridis AHK190 with high activity and thermal stability PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS. 2020.12; ( PubMed, DOI )
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Iiyama M, Numoto N, Ogawa S, Kuroda M, Morii H, Abe R, Ito N, Oda M. Molecular interactions of the CTLA-4 cytoplasmic region with the phosphoinositide 3-kinase SH2 domains. Molecular immunology. 2020.12; ( PubMed, DOI )
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Senga A, Numoto N, Yamashita M, Iida A, Ito N, Kawai F, Oda M. Multiple structural states of Ca2+ regulated PET hydrolase, Cut190, and its correlation with activity and stability. Journal of biochemistry. 2020.09; ( PubMed, DOI )
Conference Activities & Talks 【 display / non-display 】
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Nobutoshi Ito. PDBx/mmCIF format for crystallographic deposition to the Protein Data Bank (PDB). Annual Meeting of The Federation of Korean Societies for Molecular & Biomedical Sciences (FKSBS) 2020.01.10 Gwangju, South Korea
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Teikichi Ikura, Nobutoshi Ito. Micronization of a protease derived from Pin1. The 57th annual meeting of the Biophysical Society of Japan 2019.09.25
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Shotaro Yasukochi, Nobutaka Numoto, Kiminori Hori, Natsuko Tenno, Takeshi Tenno, Nobutoshi Ito, Hidekazu Hiroaki. Crystal structure of human Dishevelled1 PDZ with its inhibitor. The 57th Annual Meeting of the BSJ 2019.09.24 Miyazaki
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Nobutaka Numoto, Yoshihiro Fukumori, Kunio Miki, Nobutoshi Ito. Time-resolved structure analysis of allosteric intermediate of the giant hemoglobin. The 57th Annual Meeting of the BSJ 2019.09.24 Miyazaki
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Akihiro Nishiguchi, Nobutaka Numoto, Nobutoshi Ito, Takachika Azuma, Masayuki Oda. Antigen recognition mechanism of an affinity-matured single chain Fv antibody against anti-(4-hydroxy-3-nitrophenyl)acetyl. The 92nd Annual Meeting of the Japanese Biochemical Society 2019.09.18 Yokohama
Campus class subject 【 display / non-display 】
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Philosophy of Medicine and Dentistry,2012 - Now
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Special Lecture on Molecular Structure,2009 - Now