基本情報

写真a

山本 浩平(ヤマモト コウヘイ)

YAMAMOTO Kouhei


職名

講師

生年

1978年

研究室住所

東京医科歯科大学医歯学総合研究科人体病理学分野

研究室電話番号

03-5803-4607

研究室FAX番号

03-5803-0123

メールアドレス

yamamoto.pth2@tmd.ac.jp

ホームページ

https://www.tmd.ac.jp/med/pth1/hupathhp/

研究分野・キーワード

血液病理学、悪性リンパ腫、白血病、がん、酸化ストレス、フェロトーシス、細胞外環境、細胞外浸潤リンパ球、ゲノミクス、腫瘍学、細胞死

出身学校 【 表示 / 非表示

  • 東京医科歯科大学  医学部  医学科  2003年03月  卒業

出身大学院 【 表示 / 非表示

  • 東京医科歯科大学  医歯学総合研究科  包括病理学分野  博士課程  2007年03月  修了

取得学位 【 表示 / 非表示

  • 医学博士  

経歴(学内) 【 表示 / 非表示

  • 2007年04月
    -
    2018年03月
    東京医科歯科大学 大学院医歯学総合研究科 医歯学系専攻 先端医療開発学講座 包括病理学 助教
  • 2018年04月
    -
    2022年03月
    東京医科歯科大学 大学院医歯学総合研究科 医歯学系専攻 先端医療開発学講座 包括病理学 助教
  • 2022年04月
    -
    現在
    東京医科歯科大学 大学院医歯学総合研究科 医歯学専攻 器官システム制御学講座 人体病理学分野 講師
  • 2022年10月
    -
    現在
    東京医科歯科大学 大学院医歯学総合研究科 医歯学系専攻 器官システム制御学講座 人体病理学 講師

経歴(学外) 【 表示 / 非表示

  • 2010年10月
    -
    2011年08月
    スローンケタリング記念がんセンター ポスドク
  • 2011年09月
    -
    2013年09月
    シダーズサイナイ医療センター 客員研究員
  • 2019年11月
    -
    2021年07月
    経済産業省大臣官房ヘルスケア産業課 臨時専門アドバイザー

所属学協会 【 表示 / 非表示

  • 日本病理学会

  • 日本癌学会

  • 日本リンパ網内系学会

  • 日本臨床細胞学会

委員歴 【 表示 / 非表示

  • 2017年01月
    -
    2017年08月
    日本病理学会 病理専門医試験実施委員
  • 2018年08月
    -
    2019年07月
    日本病理学会 病理専門医試験委員

研究分野 【 表示 / 非表示

  • 病理学、とくに血液腫瘍病理

  • 実験病理学

資格、免許 【 表示 / 非表示

  • 医師

  • 病理専門医

  • 死体解剖資格

 

研究テーマ 【 表示 / 非表示

  • がん患者血中遊離RNAに関する検討,2019年10月 - 現在

  • がんにおける腫瘍浸潤リンパ球の解析,2018年03月 - 現在

  • がんの細胞外環境への依存に関する研究,2017年04月 - 現在

  • がんにおける酸化ストレスとフェロトーシス制御因子の発現の意義に関する研究,2015年04月 - 現在

  • 悪性リンパ腫に過剰発現を来すHADHA遺伝子の分子病理学的研究,2013年10月 - 2020年03月

  • B細胞性リンパ腫治療標的遺伝子の選択的スプライシングによる発現調節に関する研究,2011年09月 - 2013年09月

  • 抗アポトーシス蛋白VDAC2の白血病発症におよぼす影響に関する研究,2010年10月 - 2011年08月

  • ショットガンプロテオミクスを用いた濾胞性リンパ腫の網羅的タンパク発現解析,2009年04月 - 2010年09月

  • B細胞性リンパ腫におけるToll-like receptor の発現の検討,2008年04月 - 2009年03月

  • 血管免疫芽球性T細胞性リンパ腫における血管新生調節因子発現細胞の同定,2007年04月 - 2008年03月

  • 直腸MALTリンパ腫におけるMALT1遺伝子転座に関する検討,2006年04月 - 2007年03月

  • 骨髄異形成症候群の白血病への移行における血管新生調節因子発現の検討,2005年04月 - 2006年03月

  • 骨髄異形成症候群から白血病への移行における抗アポトーシス蛋白発現の検討,2003年04月 - 2005年03月

  • 肺腺癌におけるゲノム解析と腫瘍生物学的意義に関する研究

▼全件表示

競争的資金等の研究課題 【 表示 / 非表示

  • 難治性がんに対するセレノプロテイン遺伝子の発現制御に着目した新規細胞死の誘導

    文部科学省/日本学術振興会 : 2018年 - 2020年

  • 脂質異常に着目した悪性リンパ腫の層別化と新規治療戦略開発のための基礎的研究

    文部科学省/日本学術振興会 : 2015年 - 2016年

  • HOX関連白血病における15-PGDHによる白血病幹細胞制御機構の解明

    文部科学省/日本学術振興会

  • 腫瘍細胞の細胞外脂質依存性を利用した新規がん治療モデルの確立

    文部科学省/日本学術振興会

  • 表在型食道扁平上皮がんの空間トランスクリプトーム解析とバイオマーカー開発

    文部科学省/日本学術振興会

論文・総説 【 表示 / 非表示

  1. Kawade G, Kurata M, Matsuki Y, Fukuda S, Onishi I, Kinowaki Y, Watabe S, Ishibashi S, Ikeda M, Yamamoto M, Ohashi K, Kitagawa M, Yamamoto K. Mediation of FSP1 expression via 4-HNE accumulation contributes to acquisition of resistance to apoptosis and ferroptosis in DLBCL. Laboratory investigation; a journal of technical methods and pathology. 2024.02; 102027. ( PubMed, DOI )

  2. Morimoto M, Nawa N, Okada E, Itsui Y, Kashimada A, Yamamoto K, Akaishi Y, Yamawaki M. Elucidation of the needs for telecritical care services in Japan: a qualitative study. BMJ open. 2023.11; 13 (11): e072065. ( PubMed, DOI )

  3. Hashimoto J, Oh Y, Yamamoto K, Yoshii T, Fukushima K, Kitagawa M, Okawa A. Frequency and pathogenesis of periprosthetic atypical femoral fractures associated with total knee arthroplasty: A multicenter prospective study with complementary histopathological and biomechanical analysis. Injury. 2023.10; 111136. ( PubMed, DOI )

  4. Watabe S, Aruga Y, Kato R, Kawade G, Kubo Y, Tatsuzawa A, Onishi I, Kinowaki Y, Ishibashi S, Ikeda M, Fukawa Y, Akahoshi K, Tanabe M, Kurata M, Ohashi K, Kitagawa M, Yamamoto K. Regulation of 4-HNE via SMARCA4 Is Associated with Worse Clinical Outcomes in Hepatocellular Carcinoma. Biomedicines. 2023.08; 11 (8): ( PubMed, DOI )

  5. Sugita K, Onishi I, Nakayama R, Ishibashi S, Ikeda M, Inoue M, Narita R, Oshima S, Shimizu K, Saito S, Sato S, Moriarity BS, Yamamoto K, Largaespada DA, Kitagawa M, Kurata M. Indirect CRISPR screening with photoconversion revealed key factors of drug resistance with cell-cell interactions. Communications biology. 2023.06; 6 (1): 582. ( PubMed, DOI )

  6. Kato Yuki, Ito Takashi, Yamamoto Kouhei, Furukawa Asuka, Shintaku Hiroshi, Yamamoto Kurara, Sakai Momoka, Tomita Yoshinobu, Chino Yusuke, Uchida Keisuke, Kawada Kenro, Ohashi Kenichi. Invasive features of superficial oesophageal squamous cell carcinoma-analysis of risk factors for lymph node metastasis VIRCHOWS ARCHIV. 2023.06; 483 (5): 645-653. ( PubMed, DOI )

  7. Tanaka Keisuke, Ichikawa Ayako, Umezawa Natsuka, Yamamoto Kouhei, Yoshifuji Kota, Okada Keigo, Nogami Ayako, Umezawa Yoshihiro, Nagao Toshikage, Sakashita Chizuko, Mori Takehiko, Tohda Shuji, Koike Ryuji, Yasuda Shinsuke, Yamamoto Masahide. Lymphoproliferative disorder risk after methotrexate treatment for rheumatoid arthritis CANCER SCIENCE. 2023.06; 114 (9): 3719-3727. ( PubMed, DOI )

  8. Hirai T, Yoshii T, Inose H, Matsukura Y, Funauchi Y, Egawa S, Utagawa K, Hashimoto J, Nishizawa M, Yamamoto K, Okawa A. Intraosseous Aggressive Schwannoma in the Lumbar Spine: A Case Report. Spine surgery and related research. 2023.05; 7 (3): 288-292. ( PubMed, DOI )

  9. Matsushita Y, Liu J, Chu AKY, Tsutsumi-Arai C, Nagata M, Arai Y, Ono W, Yamamoto K, Saunders TL, Welch JD, Ono N. Bone marrow endosteal stem cells dictate active osteogenesis and aggressive tumorigenesis. Nature communications. 2023.04; 14 (1): 2383. ( PubMed, DOI )

  10. Unuma Kana, Tomomasa Dan, Noma Kosuke, Yamamoto Kouhei, Matsuyama Taka-aki, Makino Yohsuke, Hijikata Atsushi, Wen Shuheng, Ogata Tsutomu, Okamoto Nobuhiko, Okada Satoshi, Ohashi Kenichi, Uemura Koichi, Kanegane Hirokazu. Case Report: Molecular autopsy underlie COVID-19-associated sudden, unexplained child mortality FRONTIERS IN IMMUNOLOGY. 2023.04; 14 1121059. ( PubMed, DOI )

  11. Koide T, Mandai S, Kitaoka R, Matsuki H, Chiga M, Yamamoto K, Yoshioka K, Yagi Y, Suzuki S, Fujiki T, Ando F, Mori T, Susa K, Iimori S, Naito S, Sohara E, Rai T, Yokota T, Uchida S. Circulating Extracellular Vesicle-Propagated microRNA Signature as a Vascular Calcification Factor in Chronic Kidney Disease. Circulation research. 2023.02; 132 (4): 415-431. ( PubMed, DOI )

  12. Tzavlaki K, Ohata Y, Morén A, Watanabe Y, Eriksson J, Tsuchiya M, Kubo Y, Yamamoto K, Sellin ME, Kato M, Caja L, Heldin CH, Moustakas A. The liver kinase B1 supports mammary epithelial morphogenesis by inhibiting critical factors that mediate epithelial-mesenchymal transition. Journal of cellular physiology. 2023.02; ( PubMed, DOI )

  13. Tanaka H., Fukawa Y., Yamamoto K., Tanimoto K., Takemoto A., Hasumi H., Hirakawa A., Ishikawa Y., Fukuda S., Waseda Y., Yoshida S., Yokoyama M., Campbell S. C., Fujii Y.. Renal parenchymal infiltration or micronodular spread in non-metastatic clear cell renal cell carcinoma: Prognostic impact and genomic backgrounds EUROPEAN UROLOGY. 2023.02; 83 S668-S669.

  14. Tanaka H, Fukuda S, Kimura K, Fukawa Y, Yamamoto K, Fukushima H, Moriyama S, Yasuda Y, Uehara S, Waseda Y, Yoshida S, Yokoyama M, Matsuoka Y, Saito K, Tateishi U, Campbell SC, Fujii Y. Defining Tumour Shape Irregularity for Preoperative Risk Stratification of Clinically Localised Renal Cell Carcinoma. European urology open science. 2023.02; 48 36-43. ( PubMed, DOI )

  15. Nagao T, Yoshifuji K, Sadato D, Motomura Y, Saito M, Yamamoto K, Yamamoto K, Nogami A. Establishment and characterization of a new activated B-cell-like DLBCL cell line, TMD12. Experimental hematology. 2022.12; 116 37-49. ( PubMed, DOI )

  16. Kurata Morito, Antony Marie Lue, Noble-Orcutt Klara E., Rathe Susan K., Lee Yoonkyu, Furuno Hidehiro, Ishibashi Sachiko, Ikeda Masumi, Yamamoto Kouhei, Kitagawa Masanobu, Largaespada David A., Sachs Zohar. Proliferation and Self-Renewal Are Differentially Sensitive to NRASG12V Oncogene Levels in an Acute Myeloid Leukemia Cell Line MOLECULAR CANCER RESEARCH. 2022.11; 20 (11): 1646-1658. ( PubMed, DOI )

  17. Tatsumi Akiya, Hirakochi Haruka, Inoue Satomi, Tanaka Yosuke, Furuno Hidehiro, Ikeda Masumi, Ishibashi Sachiko, Taguchi Towako, Yamamoto Kouhei, Onishi Iichiroh, Sachs Zohar, Largaespada David A., Kitagawa Masanobu, Kurata Morito. Identification of NRAS Downstream Genes with CRISPR Activation Screening BIOLOGY-BASEL. 2022.11; 11 (11): ( PubMed, DOI )

  18. Koyanagi Anri, Onishi Iichiroh, Muraoka Karin, Sato Ikue, Sato Shingo, Kimura Tsuyoshi, Kishida Akio, Yamamoto Kouhei, Kitagawa Masanobu, Kurata Morito. Identification of the Factor That Leads Human Mesenchymal Stem Cell Lines into Decellularized Bone BIOENGINEERING-BASEL. 2022.10; 9 (10): ( PubMed, DOI )

  19. Hayashi Kumiko, Nogawa Daichi, Kobayashi Maki, Asakawa Ayaka, Ohata Yae, Kitagawa Shota, Kubota Kazuishi, Takahashi Hisashi, Yamada Miyuki, Oda Goshi, Nakagawa Tsuyoshi, Uetake Hiroyuki, Onishi Iichiroh, Kinowaki Yuko, Kurata Morito, Kitagawa Masanobu, Yamamoto Kouhei. Quantitative high-throughput analysis of tumor infiltrating lymphocytes in breast cancer FRONTIERS IN ONCOLOGY. 2022.09; 12 901591. ( PubMed, DOI )

  20. Asakawa A, Kawade G, Kurata M, Fukuda S, Onishi I, Kinowaki Y, Ishibashi S, Ikeda M, Watabe S, Kobayashi M, Ishibashi H, Okubo K, Kitagawa M, Yamamoto K. Stratification of lung squamous cell carcinoma based on ferroptosis regulators: Potential for new therapeutic strategies involving ferroptosis induction. Lung cancer (Amsterdam, Netherlands). 2022.01; 165 82-90. ( PubMed, DOI )

  21. Miyamoto R, Hirai T, Yoshii T, Onuma H, Inose H, Yuasa M, Matsukura Y, Morishita S, Yamamoto K, Koyanagi H, Sato S, Yagishita K, Okawa A. Surgical Strategy for Osteoid Osteoma Localized in Anterior Lumbar Vertebral Body: A Case Report. Spine surgery and related research. 2022; 6 (4): 408-411. ( PubMed, DOI )

  22. Ishisaka Y, Nosaka N, Mishima Y, Masuda T, Nagashima M, Tanaka Y, Yamamoto K, Yoshida M, Shigemitsu H. COVID-19 case of ventilator-induced lung injury on extracorporeal membrane oxygenation: Physicians' clinical struggle and ethical conflict in a novel pandemic. Clinical case reports. 2021.12; 9 (12): e05223. ( PubMed, DOI )

  23. Kinowaki Yuko, Taguchi Towako, Onishi Iichiroh, Kirimura Susumu, Kitagawa Masanobu, Yamamoto Kouhei. Overview of Ferroptosis and Synthetic Lethality Strategies INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021.09; 22 (17): ( PubMed, DOI )

  24. Sekine Y, Yamamoto K, Kurata M, Honda A, Onishi I, Kinowaki Y, Kawade G, Watabe S, Nomura S, Fukuda S, Ishibashi S, Ikeda M, Yamamoto M, Kitagawa M. HADHB, a fatty acid beta-oxidation enzyme, is a potential prognostic predictor in malignant lymphoma. Pathology. 2021.09; 54 (3): 286-293. ( PubMed, DOI )

  25. Shimada W, Tanaka H, Fukawa Y, Kimura K, Yamamoto K, Fukuda S, Fukushima H, Yasuda Y, Uehara S, Yoshida S, Yokoyama M, Matsuoka Y, Tateishi U, Campbell SC, Fujii Y. Infiltrative tumor interface with normal renal parenchyma in locally advanced renal cell carcinoma: Clinical relevance and pathological implications. International journal of urology : official journal of the Japanese Urological Association. 2021.08; 28 (12): 1233-1239. ( PubMed, DOI )

  26. Nakatsutsumi K, Morishita K, Yagi M, Doki S, Watanabe A, Ikegami N, Kobayashi T, Kojima M, Senda A, Yamamoto K, Aiboshi J, Coimbra R, Otomo Y. Vagus nerve stimulation modulates arachidonic acid production in the mesenteric lymph following intestinal ischemia-reperfusion injury. The journal of trauma and acute care surgery. 2021.07; ( PubMed, DOI )

  27. Unuma Kana, Makino Yohsuke, Yamamoto Kouhei, Hattori Shinya, Arai Nobutaka, Sakai Kentaro, Kitagawa Masanobu, Uemura Koichi, Kanegane Hirokazu. Fatal intracranial hemorrhage due to infantile acute lymphoblastic leukemia mimicking abusive head trauma JOURNAL OF FORENSIC SCIENCES. 2021.07; 66 (6): 2504-2510. ( PubMed, DOI )

  28. Fujimaru T, Kawanishi K, Mori T, Mishima E, Sekine A, Chiga M, Mizui M, Sato N, Yanagita M, Ooki Y, Nagahama K, Ohnuki Y, Hamano N, Watanabe S, Mochizuki T, Nagatsuji K, Tanaka K, Tsukamoto T, Tsushima H, Shimamoto M, Tsuji T, Kuyama T, Kawamoto S, Maki K, Katsuma A, Oishi M, Yamamoto K, Mandai S, Kikuchi H, Ando F, Mori Y, Susa K, Iimori S, Naito S, Rai T, Hoshino J, Ubara Y, Miyazaki M, Nagata M, Uchida S, Sohara E. Genetic Background and Clinicopathologic Features of Adult-onset Nephronophthisis. Kidney international reports. 2021.05; 6 (5): 1346-1354. ( PubMed, DOI )

  29. Takahashi Naohiro, Kikuchi Hiroaki, Usui Ayaka, Furusho Taisuke, Fujimaru Takuya, Fujiki Tamami, Yanagi Tomoki, Matsuura Yoshiaki, Asano Kenichi, Yamamoto Kouhei, Ando Fumiaki, Susa Koichiro, Mandai Shintaro, Mori Takayasu, Rai Tatemitsu, Uchida Shinichi, Arita Makoto, Sohara Eisei. Deletion of Alox15 improves kidney dysfunction and inhibits fibrosis by increased PGD(2) in the kidney CLINICAL AND EXPERIMENTAL NEPHROLOGY. 2021.05; 25 (5): 445-455. ( PubMed, DOI )

  30. Fukawa Yuki, Sakamoto Kei, Kugimoto Takuma, Michi Yasuyuki, Harada Hiroyuki, Yamamoto Masahide, Kitagawa Masanobu, Ikeda Tohru, Yamamoto Kouhei. Nodular lymphocyte-predominant Hodgkin lymphoma involving the hard palate PATHOLOGY INTERNATIONAL. 2021.03; 71 (3): 213-215. ( PubMed, DOI )

  31. Sanjo Nobuo, Nose Yurie, Miyamoto Shouhei, Shishido-Hara Yukiko, Saito Tatsuya, Fukuda Tetsuya, Yamamoto Kurara, Kobayashi Daisuke, Yokota Takanori. Early Pathological JC Virus Lesions in a Patient without Any MRI-based Indications INTERNAL MEDICINE. 2021; 60 (8): 1279-1282. ( PubMed, DOI )

  32. Oh Y, Yamamoto K, Yoshii T, Kitagawa M, Okawa A. Current concept of stress fractures with an additional category of atypical fractures: a perspective review with representative images. Therapeutic advances in endocrinology and metabolism. 2021; 12 20420188211049619. ( PubMed, DOI )

  33. Nishimura T, Nakamura Y, Kinoshita N, Yamamoto K, Sasaki Y, Akiyoshi K. Biocatalytic Hybrid Films Self-Assembled from Carbohydrate Block Copolymers and Polysaccharides for Enzyme Prodrug Therapy. ACS applied bio materials. 2020.12; 3 (12): 8865-8871. ( PubMed, DOI )

  34. Yamamoto Akiko, Kurata Morito, Yamamoto Kohei, Nogawa Daichi, Inoue Miori, Ishibashi Sachiko, Ikeda Masumi, Miyasaka Naoyuki, Kitagawa Masanobu. High amplification of PVT1 and MYC predict favorable prognosis in early ovarian carcinoma PATHOLOGY RESEARCH AND PRACTICE. 2020.11; 216 (11): 153175. ( PubMed, DOI )

  35. Taguchi Towako, Kurata Morito, Onishi Iichiroh, Kinowako Yuko, Sato Yunosuke, Shiono Sayuri, Ishibashi Sachiko, Ikeda Masumi, Yamamoto Masahide, Kitagawa Masanobu, Yamamoto Kouhei. SECISBP2 is a novel prognostic predictor that regulates selenoproteins in diffuse large B-cell lymphoma LABORATORY INVESTIGATION. 2020.10; 101 (2): 218-227. ( PubMed, DOI )

  36. Inoue Maiko, Isoda Takeshi, Yamashita Motoi, Tomoda Takahiro, Inoue Kento, Okano Tsubasa, Ohkawa Teppei, Endo Akifumi, Mitsuiki Noriko, Kamiya Takahiro, Yanagimachi Masakatsu, Yamamoto Kouhei, Inaba Yuichiro, Sasaki Toru, Takagi Masatoshi, Kanegane Hirokazu, Imai Kohsuke, Morio Tomohiro. Cytomegalovirus Laryngitis in Primary Combined Immunodeficiency Diseases JOURNAL OF CLINICAL IMMUNOLOGY. 2020.10; 41 (1): 243-247. ( PubMed, DOI )

  37. Yokoyama Kota, Manabe Osamu, Tsuchiya Jyunichi, Oyama Jun, Kawabe Hiroaki, Tateishi Yumiko, Asakage Takahiro, Yamamoto Kouhei, Tateishi Ukihide. A rare case of cranial and spinal leptomeningeal dissemination of recurrent ethmoid carcinoma detected by [18F]-FDG PET/CT EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2020.09; 48 (4): 1266-1267. ( PubMed, DOI )

  38. Yanai Masae, Kurata Morito, Muto Yutaka, Iha Hiroto, Kanao Toshinori, Tatsuzawa Anna, Ishibashi Sachiko, Ikeda Masumi, Kitagawa Masanobu, Yamamoto Kouhei. Clinicopathological and molecular analysis of SIRT7 in hepatocellular carcinoma PATHOLOGY. 2020.08; 52 (5): 529-537. ( PubMed, DOI )

  39. Oh Yoto, Yamamoto Kouhei, Hashimoto Jun, Fujita Koji, Yoshii Toshitaka, Fukushima Kazuyuki, Kurosa Yoshiro, Wakabayashi Yoshiaki, Kitagawa Masanobu, Okawa Atsushi. Biological activity is not suppressed in mid-shaft stress fracture of the bowed femoral shaft unlike in "typical" atypical subtrochanteric femoral fracture: A proposed theory of atypical femoral fracture subtypes BONE. 2020.08; 137 115453. ( PubMed, DOI )

  40. Kurata Morito, Antony Marie L., Noble Klara E., Rathe Susan K., Hirakouchi Haruka, Yamamoto Kouhei, Kitagawa Masanobu, Sachs Zohar, Largaespada David A.. Dose-dependent NRAS(G12V)-mediated signaling controls cell cycle progression and leukemogenic signaling in a CRISPR/Cas9-modified human AML cell line CANCER RESEARCH. 2020.08; 80 (16): ( DOI )

  41. Kaneko Kasumi, Yoshida Soichiro, Yamamoto Kouhei, Arita Yuki, Kijima Toshiki, Yokoyama Minato, Ishioka Junichiro, Matsuoka Yoh, Saito Kazutaka, Fujii Yasuhisa. Renal epithelioid angiomyolipoma: Incidence in a Japanese cohort and diagnostic utility of diffusion-weighted magnetic resonance imaging INTERNATIONAL JOURNAL OF UROLOGY. 2020.07; 27 (7): 599-604. ( PubMed, DOI )

  42. Sato Taku, Ishikawa Shun, Asano Jumpei, Yamamoto Hirona, Fujii Masayuki, Sato Toshiro, Yamamoto Kouhei, Kitagaki Keisuke, Akashi Takumi, Okamoto Ryuichi, Ohteki Toshiaki. Regulated IFN signalling preserves the stemness of intestinal stem cells by restricting differentiation into secretory-cell lineages NATURE CELL BIOLOGY. 2020.07; 22 (8): 919-926. ( PubMed, DOI )

  43. Yamamoto Akiko, Kurata Morito, Onishi Iichiroh, Sugita Keisuke, Matsumura Miwa, Ishibashi Sachiko, Ikeda Masumi, Yamamoto Kouhei, Kitagawa Masanobu. CRISPR screening identifies M1AP as a new MYC regulator with a promoter-reporter system PEERJ. 2020.05; 8 e9046. ( PubMed, DOI )

  44. Furusho Taisuke, Sohara Eisei, Mandai Shintaro, Kikuchi Hiroaki, Takahashi Naohiro, Fujimaru Takuya, Hashimoto Hiroko, Arai Yohei, Ando Fumiaki, Zeniya Moko, Mori Takayasu, Susa Koichiro, Isobe Kiyoshi, Nomura Naohiro, Yamamoto Kohei, Okado Tomokazu, Rai Tatemitsu, Uchida Shinichi. Renal TNF alpha activates the WNK phosphorylation cascade and contributes to salt-sensitive hypertension in chronic kidney disease KIDNEY INTERNATIONAL. 2020.04; 97 (4): 713-727. ( PubMed, DOI )

  45. Yamamoto K, Abe S, Honda A, Hashimoto J, Aizawa Y, Ishibashi S, Takemura T, Hanagata N, Yamamoto M, Miura O, Kurata M, Kitagawa M. Fatty acid beta oxidation enzyme HADHA is a novel potential therapeutic target in malignant lymphoma. Laboratory investigation; a journal of technical methods and pathology. 2020.03; 100 (3): 353-362. ( PubMed, DOI )

  46. Arai Ayako, Takase Hiroshi, Yoshimori Mayumi, Yamamoto Kouhei, Mochizuki Manabu, Miura Osamu. Gene expression profiling of primary vitreoretinal lymphoma CANCER SCIENCE. 2020.03; 111 (4): 1417-1421. ( PubMed, DOI )

  47. Kitagawa Masanobu, Kurata Morito, Onishi Iichiroh, Yamamoto Kouhei. Bone marrow niches in myeloid neoplasms PATHOLOGY INTERNATIONAL. 2020.02; 70 (2): 63-71. ( PubMed, DOI )

  48. Umemori M, Kurata M, Yamamoto A, Yamamoto K, Ishibashi S, Ikeda M, Tashiro K, Kimura T, Sato S, Takahashi H, Kitagawa M. The expression of MYC is strongly dependent on the circular PVT1 expression in pure Gleason pattern 4 of prostatic cancer. Medical molecular morphology. 2020.01; ( PubMed, DOI )

  49. Yasuda Shunichiro, Aoyama Satoru, Yoshimoto Ryoto, Daisuke Watanabe, Akiyama Hiroki, Umezawa Yoshihiro, Nogami Ayako, Yamamoto Kouhei, Fujiwara Takeo, Edahiro Yoko, Araki Marito, Komatsu Norio, Fukuda Tetsuya, Arai Ayako, Miura Osamu, Kawamata Norihiko. Overexpression of MPL Causes Ruxolitinib-Resistance in Myeloproliferative Neoplasms with Calreticulin Frame-Shift Mutations BLOOD. 2019.11; 134 ( DOI )

  50. Nagaishi T, Yamada D, Suzuki K, Fukuyo R, Saito E, Fukuda M, Watabe T, Tsugawa N, Takeuchi K, Yamamoto K, Arai A, Ohtsuka K, Watanabe M. Indolent T cell lymphoproliferative disorder with villous atrophy in small intestine diagnosed by single-balloon enteroscopy. Clinical journal of gastroenterology. 2019.04; 12 (5): 434-440. ( PubMed, DOI )

  51. Kawamoto Ami, Nagata Sayaka, Anzai Sho, Takahashi Junichi, Kawai Mao, Hama Minami, Nogawa Daichi, Yamamoto Kouhei, Kuno Reiko, Suzuki Kohei, Shimizu Hiromichi, Hiraguri Yui, Yui Shiro, Oshima Shigeru, Tsuchiya Kiichiro, Nakamura Tetsuya, Ohtsuka Kazuo, Kitagawa Masanobu, Okamoto Ryuichi, Watanabe Mamoru. Ubiquitin D is Upregulated by Synergy of Notch Signalling and TNF- in the Inflamed Intestinal Epithelia of IBD Patients JOURNAL OF CROHNS & COLITIS. 2019.04; 13 (4): 495-509. ( PubMed, DOI )

  52. Kawamoto A., Nagata S., Anzai S., Takahashi J., Kawai M., Hama M., Nogawa D., Yamamoto K., Kuno R., Suzuki K., Shimizu H., Hiraguri Y., Yui S., Oshima S., Tsuchiya K., Nakamura T., Ohtsuka K., Kitagawa M., Okamoto R., Watanabe M.. Synergy of Notch signalling and TNF-alpha in the inflamed intestinal epithelia of IBD patients leads to up-regulation of UBD, a ubiquitin-like protein JOURNAL OF CROHNS & COLITIS. 2019.03; 13 S91.

  53. Nagatsuma Misako, Takasawa Kei, Yamauchi Takeru, Nakagawa Ryuichi, Mizuno Tomoko, Tanaka Eriko, Yamamoto Kouhei, Uemura Noriko, Kashimadah Kenichi, Morio Tomohiro. A postzygotic KRAS mutation in a patient with Schimmelpenning syndrome presenting with lipomatosis, renovascular hypertension, and diabetes mellitus JOURNAL OF HUMAN GENETICS. 2019.02; 64 (2): 177-181. ( PubMed, DOI )

  54. Mitsumura T, Ito Y, Chiba T, Matsushima T, Kurimoto R, Tanaka Y, Kato T, Uchida K, Ito T, Yamamoto K, Eishi Y, Kitagawa M, Miyazaki Y, Inase N, Asahara H. Ablation of miR-146b in mice causes hematopoietic malignancy. Blood advances. 2018.12; 2 (23): 3483-3491. ( PubMed, DOI )

  55. Nogawa Daichi, Gulinisha Aihemaiti, Yamamoto Akiko, Onishi Iichiroh, Kurata Morito, Miyasaka Naoyuki, Yamamoto Kohei, Kitagawa Masanobu. Subcellular localization of MCM2 correlates with the prognosis of ovarian clear cell carcinoma CANCER SCIENCE. 2018.12; 109 503.

  56. Yamamoto Kohei, Abe Shinya, Kurata Morito, Honda Ayaka, Yamamoto Masahide, Kitagawa Masanobu. Ranolazine is a potential anti-tumor reagent against refractory cases in malignant lymphoma CANCER SCIENCE. 2018.12; 109 494.

  57. Kurata Morito, Yamamoto Kohei, Kitagawa Masanobu. Controllable NRAS expression system and analysis of different signals CANCER SCIENCE. 2018.12; 109 895.

  58. Hashimoto H, Nomura N, Shoda W, Isobe K, Kikuchi H, Yamamoto K, Fujimaru T, Ando F, Mori T, Okado T, Rai T, Uchida S, Sohara E. Metformin increases urinary sodium excretion by reducing phosphorylation of the sodium-chloride cotransporter. Metabolism: clinical and experimental. 2018.08; 85 23-31. ( PubMed, DOI )

  59. Takeda Takamori, Kawashima Yoshiyuki, Hirai Chiaki, Makabe Ayane, Ito Taku, Fujikawa Taro, Yamamoto Katsura, Maruyama Ayako, Tsutsumi Takeshi. Vestibular Dysfunction in Patients With Superficial Siderosis of the Central Nervous System OTOLOGY & NEUROTOLOGY. 2018.07; 39 (6): e468-e474. ( PubMed, DOI )

  60. Aihemaiti G, Kurata M, Nogawa D, Yamamoto A, Mineo T, Onishi I, Kinowaki Y, Jin XH, Tatsuzawa A, Miyasaka N, Kitagawa M, Yamamoto K. Subcellular localization of MCM2 correlates with the prognosis of ovarian clear cell carcinoma. Oncotarget. 2018.06; 9 (46): 28213-28225. ( PubMed, DOI )

  61. Yuko Kinowaki, Morito Kurata, Sachiko Ishibashi, Masumi Ikeda, Anna Tatsuzawa, Masahide Yamamoto, Osamu Miura, Masanobu Kitagawa, Kouhei Yamamoto. Glutathione peroxidase 4 overexpression inhibits ROS-induced cell death in diffuse large B-cell lymphoma. Lab. Invest.. 2018.02; ( PubMed, DOI )

  62. Junichi Maruyama, Kazutoshi Inami, Fumiyoshi Michishita, Xinliang Jiang, Hiroaki Iwasa, Kentaro Nakagawa, Mari Ishigami-Yuasa, Hiroyuki Kagechika, Norio Miyamura, Jun Hirayama, Hiroshi Nishina, Daichi Nogawa, Kouhei Yamamoto, Yutaka Hata. Novel YAP1 Activator, Identified by Transcription-Based Functional Screen, Limits Multiple Myeloma Growth. Mol. Cancer Res.. 2018.02; 16 (2): 197-211. ( PubMed, DOI )

  63. Morito Kurata, Kouhei Yamamoto, Branden S Moriarity, Masanobu Kitagawa, David A Largaespada. CRISPR/Cas9 library screening for drug target discovery. J. Hum. Genet.. 2018.02; 63 (2): 179-186. ( PubMed, DOI )

  64. Kurata Morito, Yamamoto Kouhei, Moriarity Branden S., Kitagawa Masanobu, Largaespada David A.. CRISPR/Cas9 library screening for drug target discovery(和訳中) Journal of Human Genetics. 2018.02; 63 (2): 179-186. ( 医中誌 )

  65. Kurata Morito, Yamamoto Kouhei, Kitagawa Masanobu, Noble-Orcutt Klara, Hillesheim Alexandra, Qarni Zain, Sachs Zohar, Largaespada David. Controllable oncogene; new aspects of signaling with controlling oncogene expression CANCER SCIENCE. 2018.01; 109 457.

  66. Tatsuzawa Anna, Yamamoto Kouhei, Ohata Yae, Ohyama Yoshio, Mochizuki Yumi, Komatsu Hiroyoshi, Kitagawa Masanobu. Clinicopathologic and gene mutation analysis of oral diffuse large B-cell lymphoma CANCER SCIENCE. 2018.01; 109 684.

  67. Kinowaki Yuko, Yamamoto Kohei, Kurata Morito, Onishi Iichiroh, Kitagawa Masanobu. Clinico-pathological analysis of GPX4 expression in Diffuse large B cell lymphoma CANCER SCIENCE. 2018.01; 109 683.

  68. Yae Ohata, Anna Tatsuzawa, Yoshio Ohyama, Ayako Ichikawa, Yumi Mochizuki, Sachiko Ishibashi, Yuri Itakura, Urara Sakurai, Kei Sakamoto, Tohru Ikeda, Masanobu Kitagawa, Kouhei Yamamoto. A distinctive subgroup of oral EBV+ B-cell neoplasm with polymorphous features is potentially identical to EBV+ mucocutaneous ulcer. Hum. Pathol.. 2017.11; 69 129-139. ( PubMed, DOI )

  69. Akira Toriihara, Ayako Arai, Masashi Nakadate, Kouhei Yamamoto, Ken-Ichi Imadome, Osamu Miura, Ukihide Tateishi. FDG-PET/CT findings of chronic active Epstein-Barr virus infection. Leuk. Lymphoma. 2017.10; 59 (6): 1-4. ( PubMed, DOI )

  70. Honami Takada, Ken-Ichi Imadome, Haruna Shibayama, Mayumi Yoshimori, Ludan Wang, Yasunori Saitoh, Shin Uota, Shoji Yamaoka, Takatoshi Koyama, Norio Shimizu, Kouhei Yamamoto, Shigeyoshi Fujiwara, Osamu Miura, Ayako Arai. Correction: EBV induces persistent NF-κB activation and contributes to survival of EBV-positive neoplastic T- or NK-cells. PLoS ONE. 2017.10; 12 (8): e0182682. ( PubMed, DOI )

  71. Honami Takada, Ken-Ichi Imadome, Haruna Shibayama, Mayumi Yoshimori, Ludan Wang, Yasunori Saitoh, Shin Uota, Shoji Yamaoka, Takatoshi Koyama, Norio Shimizu, Kouhei Yamamoto, Shigeyoshi Fujiwara, Osamu Miura, Ayako Arai. EBV induces persistent NF-κB activation and contributes to survival of EBV-positive neoplastic T- or NK-cells. PLoS ONE. 2017.10; 12 (3): e0174136. ( PubMed, DOI )

  72. 木脇 祐子, 山本 浩平, 倉田 盛人, 大西 威一郎, 北川 昌伸. びまん性大細胞型B細胞リンパ腫におけるGPX4の臨床病理学的検討 日本癌学会総会記事. 2017.09; 76回 P-2230. ( 医中誌 )

  73. 倉田 盛人, 山本 浩平, 北川 昌伸. 発現調整可能な癌遺伝子 癌遺伝子の発現調整による新たなシグナリングの解析について 日本癌学会総会記事. 2017.09; 76回 J-2055. ( 医中誌 )

  74. 山本 浩平, 阿部 晋也, 倉田 盛人, 本田 彩華, 武村 太郎, 花形 信孝, 北川 昌伸. 悪性リンパ腫におけるミトコンドリア三機能タンパク過剰発現の臨床病理・分子学的検討 日本癌学会総会記事. 2017.09; 76回 P-2231. ( 医中誌 )

  75. 立澤 杏奈, 山本 浩平, 大畑 八重, 大山 厳雄, 望月 裕美, 小松 博義, 北川 昌伸. 口腔びまん性大細胞B細胞性リンパ腫における遺伝子変異解析および臨床病理学的検討 日本癌学会総会記事. 2017.09; 76回 P-2233. ( 医中誌 )

  76. Kohei Kato, Takeshi Namiki, Makiko Ueno, Madoka Iikawa, Shown Tokoro, Aya Nishizawa, Kouhei Yamamoto, Keiko Miura, Hiroo Yokozeki. A Case of Primary Cutaneous Gamma-Delta T-Cell Lymphoma with Pautrier Microabscess. Annals of Dermatology. 2017.04; 29 (2): 229-232. ( PubMed, DOI )

  77. Ayano Imai, Hiroshi Takase, Ken-Ichi Imadome, Go Matsuda, Iichiro Ohnishi, Kouhei Yamamoto, Takumi Kudo, Yoji Tanaka, Taketoshi Maehara, Osamu Miura, Ayako Arai. Development of Extranodal NK/T-cell Lymphoma Nasal Type in Cerebrum Following Epstein-Barr Virus-positive Uveitis. Intern. Med.. 2017.01; 56 (11): 1409-1414. ( PubMed, DOI )

  78. Miyamoto Norikazu, Kurata Morito, Nagiri Toshiya, Abe Shinya, Yamamoto Kouhei, Onishi Iichiroh, Kirimura Susumu, Murayama Toshihiko, Hidaka Michihiro, Kitagawa Masanobu. Differential expression of ACINUS variants in bone marrow in myelodysplastic syndromes INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY. 2017; 10 (4): 4330-4338.

  79. Jin XH, Yamamoto K, Abe S, Onishi I, Kirimura S, Aihemaiti G, Kinowaki Y and Kitagawa M. Prognostic Impact of Cancer Stem Cell-Like Phenotypes in Pancreatic Ductal Adenocarcinoma Journal of Clinical and Experimental Pathology . 2016.10; 6 (295): ( DOI )

  80. Sumito Shingaki, Yumiko Yoshiki, Kouhei Yamamoto, Yasunori Ota, Kenshi Suzuki. Coexistent adrenal diffuse large B cell lymphoma in a patient with Waldenström's macrogloblinemia/lymphoplasmacytic lymphoma. Annals of Hematology. 2016.10; 95 (10): 1723-1724. ( PubMed, DOI )

  81. Shunichiro Yasuda, Keisuke Tanaka, Ayako Ichikawa, Ken Watanabe, Emi Uchida, Masahide Yamamoto, Kouhei Yamamoto, Daisuke Mizuchi, Osamu Miura, Tetsuya Fukuda. Aggressive TAFRO syndrome with reversible cardiomyopathy successfully treated with combination chemotherapy. International Journal of Hematology. 2016.10; 104 (4): 512-518. ( PubMed, DOI )

  82. Kazuhito Suzuki, Kouhei Yamamoto, Yasuhiro Arakawa, Hisashi Yamada, Keisuke Aiba, Masanobu Kitagawa. Antimyeloma activity of bromodomain inhibitors on the human myeloma cell line U266 by downregulation of MYCL. Anticancer Drugs. 2016.10; 27 (8): 756-765. ( PubMed, DOI )

  83. Susumu Kirimura, Morito Kurata, Yasunori Nakagawa, Iichiroh Onishi, Shiho Abe-Suzuki, Shinya Abe, Kouhei Yamamoto, Masanobu Kitagawa. Role of microRNA-29b in myelodysplastic syndromes during transformation to overt leukaemia. Pathology. 2016.04; 48 (3): 233-241. ( PubMed, DOI )

  84. Kouhei Yamamoto, Yukako Miwa, Shiho Abe-Suzuki, Shinya Abe, Susumu Kirimura, Iichiroh Onishi, Masanobu Kitagawa, Morito Kurata. Extramedullary hematopoiesis: Elucidating the function of the hematopoietic stem cell niche (Review). Mol Med Rep. 2016.01; 13 (1): 587-591. ( PubMed, DOI )

  85. Yoshimori M, Takada H, Imadome K, Kurata M, Yamamoto K, Koyama T, Shimizu N, Fujiwara S, Miura O, Arai A.. P-glycoprotein is expressed and causes resistance to chemotherapy in EBV-positive T-cell lymphoproliferative diseases. Cancer Medicine. 2015.10; 4 (10): 1494-1504. ( DOI )

  86. Yoshimori M, Takada H, Imadome KI, Kurata M, Yamamoto K, Koyama T, Shimizu N, Fujiwara S, Miura O, Arai A.. P-glycoprotein is expressed and causes resistance to chemotherapy in EBV-positive T-cell lymphoproliferative diseases. Cancer Med.. 2015.07; ( PubMed, DOI )

  87. Abe S, Yokomizo N, Kobayashi Y, Yamamoto K.. Confirmation of immunoglobulin heavy chain rearrangement by polymerase chain reaction using surgically obtained, paraffin-embedded samples to diagnose primary palate mucosa-associated lymphoid tissue lymphoma: A case study. Int J Surg Case Rep.. 2015.03; 10 129-133. ( PubMed, DOI )

  88. Onishi I, Nakagawa Y, Murayama T, Hidaka M, Yamamoto K, Abe-Suzuki S, Abe S, Kurata M, Kitagawa M.. Expression of multidrug resistance 1 gene in association with CXCL12 in chronic myelogenous leukaemia. Pathology.. 2014.12; 46 (7): 623-629. ( PubMed, DOI )

  89. Yukiko Tone, Yoko Kidani, Chihiro Ogawa, Kouhei Yamamoto, Masato Tsuda, Christian Peter, Herman Waldmann, Masahide Tone. Gene expression in the Gitr locus is regulated by NF-κB and Foxp3 through an enhancer. J. Immunol.. 2014.04; 192 (8): 3915-3924. ( PubMed, DOI )

  90. Yagi K, Yamamoto K, Umeda S, Abe S, Suzuki S, Onishi I, Kirimura S, Fukayama M, Arai A, Kitagawa M, Kurata M.. Expression of multidrug resistance 1 gene in B-cell lymphomas: association with follicular dendritic cells. Histopathology.. 2013.02; 62 (3): 414-420. ( PubMed, DOI )

  91. Abe S, Kurata M, Suzuki S, Yamamoto K, Aisaki K, Kanno J, Kitagawa M.. Minichromosome maintenance 2 bound with retroviral Gp70 is localized to cytoplasm and enhances DNA-damage-induced apoptosis. PLoS One.. 2012.06; 7 (6): e7-e8. ( PubMed, DOI )

  92. Umeda S, Yamamoto K, Murayama T, Hidaka M, Kurata M, Ohshima T, Suzuki S, Sugawara E, Kawano F, Kitagawa M.. Prognostic significance of HOXB4 in de novo acute myeloid leukemia. Hematology.. 2012.05; 17 (3): 125-131.

  93. Suzuki S, Kurata M, Abe S, Miyazawa R, Murayama T, Hidaka M, Yamamoto K, Kitagawa M.. Overexpression of MCM2 in myelodysplastic syndromes: association with bone marrow cell apoptosis and peripheral cytopenia. Exp Mol Pathol.. 2012.02; 92 (1): 160-166.

  94. Sugawara E, Yamamoto K, Umeda S, Suzuki S, Kurata M, Endo Y, Uchibori K, Akashi T, Inase N, Kitagawa M.. Giant cell carcinoma causing rapidly progressive respiratory failure as the presenting feature of AIDS. Int J STD AIDS.. 2012.02; 23 (7): e7-e8.

  95. Masanobu Kitagawa, Morito Kurata, Kouhei Yamamoto, Shinya Abe, Shiho Suzuki, Shigeaki Umeda.. Molecular pathology of myelodysplastic syndromes: biology of medullary stromal and hematopoietic cells (review). Mol Med Report.. 2011.08; 4 (4): 591-596. ( PubMed )

  96. Kurata M, Abe S, Suzuki S, Li N, Ohnishi I, Hasegawa M, Yamamoto K, Kitagawa M.. DNA damage-induced apoptosis and genetic background of the host: host-specific signaling enhancers of apoptosis. J Med Dent Sci.. 2011.07; 58 (2): 85-88. ( PubMed )

  97. Smith TJ, Yamamoto K, Kurata M, Yukimori A, Suzuki S, Umeda S, Sugawara E, Kojima Y, Sawabe M, Nakagawa Y, Suzuki K, Crawley JT, Kitagawa M.. Differential expression of Toll-like receptors in follicular lymphoma, diffuse large B-cell lymphoma and peripheral T-cell lymphoma. Exp Mol Pathol.. 2011.07; 58 (2): 85-88. ( PubMed, DOI )

  98. Niino D, Yamamoto K, Tsuruta O, Maeda T, Yakushijin Y, Aoki R, Kimura Y, Hashikawa K, Kiyasu J, Takeuchi M, Sugita Y, Ohshima K.. Regression of rectal mucosa-associated lymphoid tissue (MALT) lymphoma after antibiotic treatments. Pathol Int.. 2010.07; 60 (6): 438-442. ( PubMed, DOI )

  99. Kuninaka N, Kurata M, Yamamoto K, Suzuki S, Umeda S, Kirimura S, Arai A, Nakagawa Y, Suzuki K, Kitagawa M.. Expression of Toll-like receptor 9 in bone marrow cells of myelodysplastic syndromes is down-regulated during transformation to overt leukemia. Exp Mol Pathol.. 2010.04; 88 (2): 293-298. ( PubMed, DOI )

  100. Hasegawa M, Kurata M, Yamamoto K, Yoshida K, Aizawa S, Kitagawa M.. A novel role for acinus and MCM2 as host-specific signaling enhancers of DNA-damage-induced apoptosis in association with viral protein gp70. Leuk Res.. 2009.08; 33 (8): 1100-1107. ( PubMed, DOI )

  101. Konstantinou K, Yamamoto K, Ishibashi F, Mizoguchi Y, Kurata M, Nakagawa Y, Suzuki K, Sawabe M, Ohta M, Miyakoshi S, Crawley JT, Kitagawa M.. Angiogenic mediators of the angiopoietin system are highly expressed by CD10-positive lymphoma cells in angioimmunoblastic T-cell lymphoma. Br J Haematol.. 2009.03; 144 (5): 696-704. ( PubMed, DOI )

  102. Shiraishi J, Nakagawa Y, Kurata M, Yamamoto K, Abe Y, Toyoda Y, Suzuki K, Kitagawa M, Takemura T.. Follicular lymphoma with marked infiltration of eosinophils. Pathol Int.. 2008.11; 58 (11): 701-705.

  103. Kurata M, Nakagawa Y, Yamamoto K, Suzuki K, Kitagawa M.. Induction of integrin beta1 expression in bone marrow cells after chemotherapy correlates with the overexpression of lung resistance protein and poor outcome in patients with multiple myeloma. Am J Hematol.. 2008.09; 83 (9): 755-757. ( PubMed, DOI )

  104. Karube K, Aoki R, Nomura Y, Yamamoto K, Shimizu K, Yoshida S, Komatani H, Sugita Y, Ohshima K.. Usefulness of flow cytometry for differential diagnosis of precursor and peripheral T-cell and NK-cell lymphomas: analysis of 490 cases. Pathol Int.. 2008.02; 58 (2): 89-97.

  105. Shimizu K, Karube K, Arakawa F, Nomura Y, Komatani H, Yamamoto K, Yoshida S, Aoki R, Sugita Y, Takeshita M, Ohshima K.. Upregulation of CC chemokine ligand 18 and downregulation of CX3C chemokine receptor 1 expression in human T-cell leukemia virus type 1-associated lymph node lesions: Results of chemokine and chemokine receptor DNA chip analysis. Cancer Sci.. 2007.12; 98 (12): 1875-1850. ( PubMed )

  106. Abe S, Hasegawa M, Yamamoto K, Kurata M, Nakagawa Y, Suzuki K, Takizawa T, Kitagawa M.. Rapid induction of IAP family proteins and Smac/DIABLO expression after proapoptotic stimulation with doxorubicin in RPMI 8226 multiple myeloma cells. Exp Mol Pathol.. 2007.12; 83 (3): 405-412. ( PubMed )

  107. Keith T, Araki Y, Ohyagi M, Hasegawa M, Yamamoto K, Kurata M, Nakagawa Y, Suzuki K, Kitagawa M.. Regulation of angiogenesis in the bone marrow of myelodysplastic syndromes transforming to overt leukaemia. Br J Haematol.. 2007.05; 137 (3): 206-215. ( PubMed )

  108. Karube K, Guo Y, Suzumiya J, Sugita Y, Nomura Y, Yamamoto K, Shimizu K, Yoshida S, Komatani H, Takeshita M, Kikuchi M, Nakamura N, Takasu O, Arakawa F, Tagawa H, Seto M, Ohshima K.. CD10-MUM1+ follicular lymphoma lacks BCL2 gene translocation and shows characteristic biologic and clinical features. Blood.. 2007.04; 109 (7): 3076-3079.

  109. Kurata M, Hasegawa M, Nakagawa Y, Abe S, Yamamoto K, Suzuki K, Kitagawa M.. Expression dynamics of drug resistance genes, multidrug resistance 1 (MDR1) and lung resistance protein (LRP) during the evolution of overt leukemia in myelodysplastic syndromes. Exp Mol Pathol.. 2006.12; 81 (3): 249-254.

  110. Nakagawa Y, Abe S, Kurata M, Hasegawa M, Yamamoto K, Inoue M, Takemura T, Suzuki K, Kitagawa M.. IAP family protein expression correlates with poor outcome of multiple myeloma patients in association with chemotherapy-induced overexpression of multidrug resistance genes. Am J Hematol.. 2006.12; 81 (11): 824-831.

  111. Tamura K, Aoyagi M, Wakimoto H, Tamaki M, Yamamoto K, Yamamoto M, Ohno K.. Malignant transformation eight years after removal of a benign epidermoid cyst: a case report. J Neurooncol.. 2006.08; 79 (1): 67-72.

  112. Kitagawa M, Utsuyama M, Kurata M, Yamamoto K, Yuasa Y, Ishikawa Y, Arai T, Hirokawa K.. Cancer and aging: symposium of the 27th annual meeting of the Japanese society for biomedical gerontology, Tokyo. Cancer Immunol Immunother.. 2005.07; 54 (7): 623-634.

  113. Nakagawa Y, Hasegawa M, Kurata M, Yamamoto K, Abe S, Inoue M, Takemura T, Hirokawa K, Suzuki K, Kitagawa M.. Expression of IAP-family proteins in adult acute mixed lineage leukemia (AMLL). Am J Hematol.. 2005.03; 78 (3): 173-180.

  114. Expression of IAP family proteins in myelodysplastic syndromes transforming to overt leukemia. Leukemia Research. 2004.11;

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  116. 木脇 祐子, 山本 浩平. 【病理診断クイックリファレンス 2023】(第16章)血液・骨髄 骨髄異形成症候群 病理と臨床. 2023.04; 41 (臨増): 244. ( 医中誌 )

  117. 木脇 祐子, 山本 浩平. 【病理診断クイックリファレンス 2023】(第16章)血液・骨髄 成人T細胞白血病/リンパ腫 病理と臨床. 2023.04; 41 (臨増): 243. ( 医中誌 )

  118. 田口 登和子, 山本 浩平. 【病理診断クイックリファレンス 2023】(第16章)血液・骨髄 慢性骨髄性白血病 病理と臨床. 2023.04; 41 (臨増): 241. ( 医中誌 )

  119. 田口 登和子, 山本 浩平. 【病理診断クイックリファレンス 2023】(第16章)血液・骨髄 慢性リンパ性白血病 病理と臨床. 2023.04; 41 (臨増): 242. ( 医中誌 )

  120. Shinohara Hajime, Kobayashi Maki, Hayashi Kumiko, Nogawa Daichi, Asakawa Ayaka, Ohata Yae, Kubota Kazuishi, Takahashi Hisashi, Yamada Miyuki, Tokunaga Masanori, Kinugasa Yusuke, Oda Goshi, Nakagawa Tsuyoshi, Onishi Iichiroh, Kinowaki Yuko, Kurata Morito, Ohashi Kenichi, Kitagawa Masanobu, Yamamoto Kouhei. Spatial and Quantitative Analysis of Tumor-Associated Macrophages: Intratumoral CD163-/PD-L1+TAMs as a Marker of Favorable Clinical Outcomes in Triple-Negative Breast Cancer INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022.11; 23 (21): ( PubMed, DOI )

  121. Tanaka Yosuke, Kambayashi Hidetaka, Yamamoto Akiko, Onishi Iichiroh, Sugita Keisuke, Matsumura Miwa, Ishibashi Sachiko, Ikeda Masumi, Yamamoto Kouhei, Kitagawa Masanobu, Kurata Morito. Efficient Identification of the MYC Regulator with the Use of the CRISPR Library and Context-Matched Database Screenings INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022.07; 23 (14):

  122. Morishita Mayu, Arimoto-Matsuzaki Kyoko, Kitamura Masami, Niimura Kyohei, Iwasa Hiroaki, Maruyama Junichi, Hiraoka Yuichi, Yamamoto Kohei, Kitagawa Masanobu, Miyamura Norio, Nishina Hiroshi, Hata Yutaka. Characterization of mouse embryonic fibroblasts derived from Rassf6 knockout mice shows the implication of Rassf6 in the regulation of NF-kappa B signaling GENES TO CELLS. 2021.12; 26 (12): 999-1013. ( PubMed, DOI )

  123. Onishi Iichiroh, Yamamoto Kouhei, Kinowaki Yuko, Kitagawa Masanobu, Kurata Morito. To Discover the Efficient and Novel Drug Targets in Human Cancers Using CRISPR/Cas Screening and Databases INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021.11; 22 (22): ( PubMed, DOI )

  124. Yasuda Shunichiro, Aoyama Satoru, Yoshimoto Ryoto, Li Huixin, Watanabe Daisuke, Akiyama Hiroki, Yamamoto Kouhei, Fujiwara Takeo, Najima Yuho, Doki Noriko, Sakaida Emiko, Edahiro Yoko, Imai Misa, Araki Marito, Komatsu Norio, Miura Osamu, Kawamata Norihiko. MPL overexpression induces a high level of mutant-CALR/MPL complex: a novel mechanism of ruxolitinib resistance in myeloproliferative neoplasms with CALR mutations INTERNATIONAL JOURNAL OF HEMATOLOGY. 2021.10; 114 (4): 424-440. ( PubMed, DOI )

  125. Nogami A, Yamamoto M, Yamamoto K, Ito M, Umezawa Y, Tohda S, Miura O, Fukuda T. [Marginal zone lymphoma-like primary bone marrow lymphoma with long-term pancytopenia preceding diagnosis]. [Rinsho ketsueki] The Japanese journal of clinical hematology. 2020; 61 (10): 1469-1475. ( PubMed, DOI )

  126. 倉田 盛人, 山本 浩平, 北川 昌伸. NRAS発現調整可能システムとシグナルの解析(Controllable NRAS expression system and analysis of different signals) 日本癌学会総会記事. 2018.09; 77回 1549. ( 医中誌 )

  127. 山本 浩平, 阿部 晋也, 倉田 盛人, 本田 彩華, 山本 正英, 北川 昌伸. ラノラジンは難治性悪性リンパ腫に対する有望な抗腫瘍薬としての可能性を有する(Ranolazine is a potential anti-tumor reagent against refractory cases in malignant lymphoma) 日本癌学会総会記事. 2018.09; 77回 528. ( 医中誌 )

  128. 野川 大地, グリニサ・アヒマティ , 山本 阿紀子, 大西 威一郎, 倉田 盛人, 宮坂 尚幸, 山本 浩平, 北川 昌伸. 卵巣癌におけるMCM2タンパクの細胞内局在に着目した臨床病理学的検討(Subcellular localization of MCM2 correlates with the prognosis of ovarian clear cell carcinoma) 日本癌学会総会記事. 2018.09; 77回 751. ( 医中誌 )

  129. Yoshimori M, Imadome KI, Tomii S, Yamamoto K, Miura O, Arai A. [Cerebrospinal fluid findings in chronic active Epstein-Barr virus infection with central nervous system involvement]. [Rinsho ketsueki] The Japanese journal of clinical hematology. 2018; 59 (4): 367-372. ( PubMed, DOI )

  130. Oda G, Nakagawa T, Sato T, Kuwayama T, Yamamoto K, Kawachi H, Kubota K, Sugihara K.. A case of stage IV breast cancer with bone metastases that responded well for long-term to hormonal therapy. Gan To Kagaku Ryoho.. 2010.11; 37 (12): 2753-2755.

  131. 山本浩平, 北川昌伸. 急性骨髄性白血病 病理と臨床. 2009; 27 (1): 1046-1051.

  132. 山本浩平, 北川昌伸. 老人と癌,特に造血器・リンパ球系腫瘍 病理と臨床. 2006; 24 (12): 1282-1288.

  133. Takazawa R, Kawakami S, Yamamoto K, Kubo Y, Kageyama Y, Kihara K.. A case of prostatic duct adenocarcinoma: its clinical significance in comparison with typical acinar adenocarcinoma. Hinyokika Kiyo.. 2008.03; 54 (3): 243-247.

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書籍等出版物 【 表示 / 非表示

  1. 山本浩平, 北川昌伸. 病理と臨床クイックリファレンス. 文光堂, 2015.03 骨髄

講演・口頭発表等 【 表示 / 非表示

  1. Kota Yoshifuji, Yotaro Motomura, Makiko Saito, Ayako Nogami, Genji Kawade, Shiori Watabe, Kouhei Yamamoto, Takahiko Mori, Toshikage Nagao.. TPL2, a New Prognostic Factor and a Potential Therapeutic Target in ABC-DLBCL.. 64th ASH Annual Meeting and Exposition. 2022.12.11 New Orleans

  2. Ayako Arai, Hiroshi Takase, Kouhei Yamamoto, Hiroki Akiyama, Manabu Mochizuki, Osamu Miura. Gene expression profiling of primary vitreoretinal lymphoma. 57th ASH Annual Meeting and Exposition 2015.12.05 Orlando

  3. 石原 健作, 藤原 基裕, 山本 浩平, 横山 みなと, 廣瀬 航平, 相馬 貴彦, 小林 正貴, 中村 祐基, 范 博, 石川 雄大, 内田 裕將, 福田 翔平, 上原 翔, 田中 一, 吉田 宗一郎, 松岡 陽, 明石 巧, 藤井 靖久. 出産1ヵ月後に膀胱タンポナーデを契機に発見され,自然退縮した膀胱原発炎症性筋線維芽細胞腫瘍の1例. 泌尿器外科 2023.10.01

  4. 藤野 淳也, 高橋 直, 柳井 健作, 石黒 太郎, 山本 浩平, 西田 陽一郎, 横田 隆徳. 痙性対麻痺と感覚障害で発症し,慢性脊髄炎と末梢神経障害を呈した神経サルコイドーシスの65歳男性例. 日本内科学会関東地方会 2023.10.01

  5. 桑原 宏哉, 上野 太郎, 遠藤 明史, 平井 高志, 山本 浩平, 榛澤 義明, 田中 佑美, 石橋 恵理, 萬 巴里子, 坂巻 泰則, 矢島 祐介, 黒木 大陽, 小池 竜司. ブロックチェーン技術の導入による脊椎症の臨床研究の効率化. 臨床神経学 2023.09.01

  6. 春原 涼, 島田 翔, 佐藤 万瑛, 村川 美也子, 山本 浩平, 園田 史朗, 青木 光, 榊原 里江, 柴田 翔, 本多 隆行, 白井 剛, 古澤 春彦, 立石 知也, 岡本 師, 宮崎 泰成. 肺癌治療中に繰り返す免疫介在性肝機能障害(IMH)にミコフェノール酸モフェチル(MMF)併用治療が奏功した1例. 日本結核・非結核性抗酸菌症学会関東支部学会・日本呼吸器学会関東地方会合同学会プログラム・抄録集 2023.09.01

  7. 田中 一, 布川 裕規, 山本 浩平, 谷本 幸介, 竹本 暁, 蓮見 壽史, 平川 晃弘, 石川 雄大, 福田 翔平, 早稲田 悠馬, 吉田 宗一郎, 横山 みなと, 藤井 靖久. 淡明細胞型腎細胞癌における腎実質浸潤/進展の意義 予後への影響と遺伝学的背景(Renal parenchymal infiltration or micronodular spread in clear cell renal cell carcinoma: prognostic impact and genomic backgrounds). 日本泌尿器科学会総会 2023.04.01

  8. 加藤 祐己, 渡邉 まゆ美, 伊藤 栄作, 笠原 一郎, 冨井 翔平, 山本 浩平, 大橋 健一. TAFRO症候群が強く疑われた一例. 第111回日本病理学会総会 2022.04.14 神戸国際展示場

  9. 新井文子、高瀬博、山本浩平、秋山弘樹、望月學、三浦修. 原発性硝子体網膜リンパ腫の遺伝子発現プロファイリング. 第77回日本血液学会総会 2015.10.17 金沢

  10. 小松穂菜実、今留謙一、柴山春奈、矢田知隆、山田桃子、山本浩平、小山孝敏、藤原成悦、三浦修、新井文子. EBV陽性T,NKリンパ増殖症におけるSTAT3の恒常的活性化とその意義. 第24回EBV感染症研究会 2015.03.15 東京

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受賞学術賞 【 表示 / 非表示

  • 日本網内系学会優秀演題,日本網内系学会,2010年06月

その他業績 【 表示 / 非表示

  • 「 腎臓がんの術後再発リスクを見極める新たな鍵 」 ― がんと正常部との境界部のパターンでより高精度な再発予測が可能に ―,2024年09月

    Modern Pathology

  • 「COVID-19に関連した小児突然死の背景にある希少疾患の診断に成功」 ― 世界初の分子剖検によるLZTR1変異を有するNoonan症候群の診断例 ―,2023年04月

    Frontiers in Immunology

  • 「東京医科歯科大学と医療・ヘルスケア系ベンチャー・スタートアップ10社、 学生の未来の多様性実現にむけた教育連携体制を構築」 ―全学部学生に対し単位取得型ベンチャー企業インターンシップの機会を提供―,2022年09月

  • 株式会社Magic Shieldsと東京医科歯科大学との共同研究が、経済産業省主催第2回新事業創出ワーキンググループで紹介されました,2022年03月

  • 国立大学法人 東京医科歯科大学と株式会社シンクロアイズ  5領域にわたる多部門共同の視野共有デバイスを用いた共同研究を開始,2022年03月

  • 東京医科歯科大学とサスメド、ブロックチェーン技術を用いたモニタリング手法の開発で AMED 採択,2021年04月

  • アカデミア初! 経済産業省Healthcare Innovation Hubのサポーター団体として登録されました,2020年02月


  • 「 口腔EBウイルス陽性高悪性度B細胞腫瘍は予後良好であることを証明 」 WHO新分類のEBウイルス陽性粘膜皮膚潰瘍に合致―,2017年11月

    Human Pathology

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担当授業科目(学内) 【 表示 / 非表示

  • CPE,2015年 - 現在

  • がんプロジェクト,2014年 - 現在

  • 腫瘍学ブロック,2014年 - 現在

  • CC1 腹部,2013年 - 2014年

  • 呼吸器ブロック,2009年 - 現在

  • 血液ブロック,2007年 - 現在

  • 病理学実習,2007年 - 2010年

  • CC1 病理,2007年 - 2010年

▼全件表示

社会貢献活動 【 表示 / 非表示

  • 単位取得型ベンチャー企業インターンシップ制度について,読売新聞社,読売新聞,2024年02月09日 - 現在

  • 単位取得型インターンシップ制度について,朝日インタラクティブ株式会社,CNET Japan,2022年10月06日

  • 医学生がベンチャー企業でインターンシップを行う意義について,医学書院,週刊医学界新聞,2022年10月05日 - 現在

  • 経済産業省ヘルスケア産業課Healthcare Innovation Hubアドバイザー,2021年08月01日 - 現在

  • 経済産業省大臣官房ヘルスケア産業課臨時専門アドバイザー,2019年11月01日 - 2021年07月31日