Personnel Information

写真a

HIGASHIHORI Norihisa


Job title

Junior Associate Professor

Mail Address

The inquiry by e-mail is 《here》
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Graduating School 【 display / non-display 】

  • Tokyo Medical and Dental University, Faculty of Dentistry, 2000, Graduated

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Graduate School 【 display / non-display 】

  • Tokyo Medical and Dental University, Medical and Dental Sciences, Maxillofacial Orthodontics, Doctor's Course, 2004, Completed

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Campus Career 【 display / non-display 】

  • 2010.04
    -
    2019.03
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Maxillofacial and Neck Reconstruction， Maxillofacial Orthognathics， Assistant Professor
  • 2019.04
    -
    Now
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Maxillofacial and Neck Reconstruction， Maxillofacial Orthognathics， Junior Associate Professor
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Research Areas 【 display / non-display 】

  • Developmental dentistry

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Qualification Acquired 【 display / non-display 】

  • Dentist

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Published Papers & Misc 【 display / non-display 】

  1. Kano S, Higashihori N, Thiha P, Takechi M, Iseki S, Moriyama K. The role of the histone methyltransferase SET domain bifurcated 1 during palatal development Biochemical and Biophysical Research Communications. 2022.04; 598 74-80. ( DOI )

  2. Thiha P, Higashihori N, Kano S, Moriyama K. Histone methyltransferase SET domain bifurcated 1 negatively regulates parathyroid hormone/parathyroid hormone-related peptide receptor to control chondrocyte proliferation in Meckel’s cartilage Archives of Oral Biology . 2021.08; 131 105251. ( DOI )

  3. Watanabe M, Hong C, Liu Z, Takao C, Suga T, Huyen Tu TT, Yoshikawa T, Takenoshita M, Sato Y, Higashihori N, Moriyama K, Motomura H, Toyofuku A. Case Report: Iatrogenic Dental Progress of Phantom Bite Syndrome: Rare Cases With the Comorbidity of Psychosis. Frontiers in Psychiatry. 2021.07; 12 701232. ( PubMed, DOI )

  4. Takayuki Suga, Trang Thi Huyen Tu, Miho Takenoshita, Norihisa Higashihori, Yuji Kabasawa, Takashi Ono, Keiji Moriyama, Akira Toyofuku. Psychosocial indication for orthognathic surgery in patients with psychiatric comorbidities. Psychiatry Clin Neurosci. 2020.11; 74 (11): 621-623. ( PubMed, DOI, ichushi )

  5. Teramoto A, Suzuki S, Higashihori N, Ohbayashi N, Kurabayashi T, Moriyama K. 3D evaluation of the morphological and volumetric changes of the tongue and oral cavity before and after orthognathic surgery for mandibular prognathism: a preliminary study. Progress in Orthodontics . 2020.08; 21 (1): 30. ( PubMed, DOI )

  6. Takahashi Y, Higashihori N, Yasuda Y, Takada JI, Moriyama K. Examination of craniofacial morphology in Japanese patients with congenitally missing teeth: a cross-sectional study. Progress in orthodontics. 2018.10; 19 (1): 38. ( PubMed, DOI )

  7. Higashihori N, Takada JI, Katayanagi M, Takahashi Y, Moriyama K. Frequency of missing teeth and reduction of mesiodistal tooth width in Japanese patients with tooth agenesis. Progress in orthodontics. 2018.08; 19 (1): 30. ( PubMed, DOI )

  8. Kamata H, Higashihori N, Fukuoka H, Shiga M, Kawamoto T, Moriyama K. Comprehending the three-dimensional mandibular morphology of facial asymmetry patients with mandibular prognathism. Progress in orthodontics. 2017.12; 18 (1): 43. ( PubMed, DOI )

  9. Higashihori N, Lehnertz B, Sampaio A, Underhill T M, Rossi F, Richman J M . Methyltransferase G9A Regulates Osteogenesis via Twist Gene Repression. Journal of Dental Research. 2017.09; 96 (10): 1136-1144. ( PubMed, DOI )

  10. Yahiro K, Higashihori N, Moriyama K. Histone methyltransferase Setdb1 is indispensable for Meckel's cartilage development. Biochem. Biophys. Res. Commun.. 2017.01; 482 (4): 883-888. ( PubMed, DOI )

  11. Sato M, Baba Y, Haruyama N, Higashihori N, Tsuji M, Suzuki S, Moriyama K. Clinicostatistical analysis of congenitally missing permanent teeth in Japanese patients with cleft lip and/or palate Orthodontic Waves. 2016.06; 75 (2): 41-45.

  12. Erika Suzuki-Okamura, Norihisa Higashihori, Tatsuo Kawamoto, Keiji Moriyama. Three-dimensional analysis of hard and soft tissue changes in patients with facial asymmetry undergoing 2-jaw surgery. Oral Surg Oral Med Oral Pathol Oral Radiol. 2015.09; 120 (3): 299-306. ( PubMed, DOI )

  13. Shiying Liu, Norihisa Higashihori, Kohei Yahiro, Keiji Moriyama. Retinoic acid inhibits histone methyltransferase Whsc1 during palatogenesis. Biochem. Biophys. Res. Commun.. 2015.03; 458 (3): 525-530. ( PubMed, DOI )

  14. Higashihori N, Buchtova M, Richman JM. The function and regulation of TBX22 in avian frontonasal morphogenesis. Dev Dyn. 2010.02; 239 (2): 458-473. ( PubMed, DOI )

  15. Mukai-Higashihori K, Baba Y, Tetsumura A, Tsuji M, Ishizaki T, Higashihori N, Ohbayashi N, Kurabayashi T, Suzuki S, Ohyama K. Ultrasonographic assessment of new bone formation in maxillary distraction osteogenesis. J Oral Maxillofac Surg. 2008.08; 66 (8): 1750-1753. ( PubMed, DOI )

  16. Higashihori N, Song Y, Richman JM. Expression and regulation of the decoy bone morphogenetic protein receptor BAMBI in the developing avian face. Developmental Dynamics. 2008.05; 237 (5): 1500-1508. ( PubMed, DOI )

  17. Suda N, Handa S, Higashihori N, Ogawa T, Tsuji M, Ohyama K.. Orthodontic treatment of a patient with Stickler syndrome. The Angle Orthodontist. 2007.09; 77 (5): 931-939. ( PubMed, DOI )

  18. Ohkuma M, Funato N, Higashihori N, Murakami M, Ohyama K, Nakamura M. Unique CCT repeats mediate transcription of the TWIST1 gene in mesenchymal cell lines. Biochem. Biophys. Res. Commun.. 2007.01; 352 (4): 925-931. ( PubMed, DOI )

  19. Funato N, Twigg SR, Higashihori N, Ohyama K, Wall SA, Wilkie AO, Nakamura M. Functional analysis of natural mutations in two TWIST protein motifs. Hum Mutat. 2005.06; 25 (6): 550-556. ( PubMed, DOI )

  20. Takahashi E, Funato N, Higashihori N, Hata Y, Gridley T, Nakamura M. Snail regulates p21(WAF/CIP1) expression in cooperation with E2A and Twist. Biochem Biophys Res Commun. 2004.12; 325 (4): 1136-1144. ( PubMed, DOI )

  21. Suda N, Matsuda A, Yoda S, Ishizaki T, Higashihori N, Kim F, Otani-Saito K, Ohyama K. Orthodontic treatment of a case of Becker muscular dystrophy Orthodontics & Craniofacial Research. 2004; 7 (1): 55-62.

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Conference Activities & Talks 【 display / non-display 】

  1. Inoue A, Higashihori N, Takeuchi S, Moriyama K. A case report of Parry-Romberg syndrome with mandibular prognathism treated by surgical orthodontic treatment. the 55th Annual Congress of the KAO and the 13th Asian Pacific Orthodontic Congress(APOC) 2022.10.28 Korea / ondemand

  2. Thiha P, Higashihori N, Kano S, Moriyama K. Histone methyltransferase SETDB1 negatively regulates PTH/PTHrP receptor in chondrocytes. The 68th Annual Meeting of Japanese Association for Dental Research 2020.11.07 virtual congress

  3. Kadota-Watanabe C, Higashihori N, Kang J, Ogawa T, Yoda T, Moriyama K. A skeletal Class II open bite case in which functional disharmony was improved after surgical-orthodontic treatment. The 59th Congress of the Korean Association of Maxillofacial Plastic and Reconstructive Surgeons 2020.10.29 e-conference

  4. Kano S, Higashihori N, Ogura K, Kadota-Watanabe C, Matsumoto T, Takahara N, Yoda T, Moriyama K. Skeletal mandibular retrognathic cases in which occlusion and respiratory function during sleep were improved after surgical-orthodontic treatment . The 9th Internarional Orthodontic Congress, The 12th Asian Pacific Orthodontic Conference, The 79th Annual Meeting of the Japanese Orthodontic Society 2020.10.04 ondemand

  5. Kamimoto H, Higashihori N, Akiyama S, Ogasawara T, Kadota-Watanabe C, Matsumoto T, Moriyama K. Usefulness of the Index of Orthognathic Functional Treatment Need in Surgical-Orthodontic Treatment for Japanese Skeletal Class III Patients: A Retrospective Study. The 9th Internarional Orthodontic Congress, The 12th Asian Pacific Orthodontic Conference, The 79th Annual Meeting of the Japanese Orthodontic Society 2020.10.04 ondemand

  6. Funahashi K, Kobayashi Y, Niki Y, Higashihori N, Nakakuki K,Yoda T, Moriyama K. A Case Report of Severe Class II Malocclusion Treated with Anterior Segmental Maxillary Osteotomy and Genioplasty. The 9th Internarional Orthodontic Congress, The 12th Asian Pacific Orthodontic Conference, The 79th Annual Meeting of the Japanese Orthodontic Society 2020.10.04 ondemand

  7. Arimura M, Yoshizawa Araki M, Unnai Yasuda Y, Higashihori N, Ogawa T, Moriyama K. A Survey of Unilateral Cleft Lip and Palate Patients Who Missed Orthodontic Management Until the Permanent Dentition Stage. The 9th Internarional Orthodontic Congress, The 12th Asian Pacific Orthodontic Conference, The 79th Annual Meeting of the Japanese Orthodontic Society 2020.10.04 ondemand

  8. Higashihori N, Yahiro K, Phyo Thiha, Kano S, Moriyama K. Histone Methyltransferase SETDB1 is Crucial for Craniofacial Development. 97th General Session & Exhibition of International Association for Dental Research 2019.06.19 Vancouver, Canada

  9. Higashihori N, Moriyama K. Long-term management of occlusion after surgical-orthodontic treatment for jaw deformity patient with schizophrenia: a case report. The 11th Asian Pacific Orthodontic Conference(APOC 2018) 2018.03.05 Boracay, Phillipines

  10. Hikita R, Higashihori N, Kadota C, Akiyama S, Takahashi Y, Ito Y, Moriyama K. Effects of tongue-jaw bone relationship on respiratory function during sleep after orthognathic surgery in patients with mandibular prognathism: Comparison between one-jaw and two-jaw surgery. The 11th Asian Pacific Orthodontic Conference(APOC 2018) 2018.03.05 Boracay, Phillipines

  11. Ito Y, Takahashi Y, Hikita R, Watanabe C, Akiyama S, Higashihori N, Moriyama K. Long-term changes in clinical crown height after surgical orthodontic treatment for mandibular prognathism. The 10th Asia Pacific orthodontic Conference and 11th Annual Meeting of the Indonesian Association of Orthodontists 2016.09.03 Bali,Indonesia

  12. Higashihori N, Hikita R, Moriyama K. Surgical-orthodontic treatment for facial asymmetry patient whose occlusal plane canted opposite to the mandibular deviation. The 10th Asia Pacific orthodontic Conference and 11th Annual Meeting of the Indonesian Association of Orthodontists 2016.09.03 Bali,Indonesia

  13. Yuki Takahashi, Norihisa Higashihori, Keiji Moriyama. Correction of a high-angle class II malocclusion with condylar resorption using a skeletal anchorage system. 2015 APOS (Asian Pacific Orthodontic Society) Resident Forum 2015.12.04 Taiwan

  14. Chiho Watanabe, Norihisa Higashihori, Rina Hikita, Tsutomu Matsumoto, Yosuke Ito, Tatsuo Kawamoto, Keiji Moriyama. Long-term observations after surgical orthodontic treatment for mandibular prognathism with facial asymmetry. 8th International Orthodontic Congress 2015.09.27 London

  15. Tsutomu Matsumoto, Norihisa Higashihori, Rina Hikita, Chiho Watanabe, Jun Miyamoto, Tatsuo Kawamoto, Shoichi Suzuki, Keiji Moriyama. Three-dimensional analysis of lower lip movement during articulation in patients with mandibular prognathism by motion capture system. 8th International Orthodontic Congress 2015.09.27 London

  16. Chiho Watanabe, Norihisa Higashihori, Rina Hikita, Tsutomu Matsumoto, Yosuke Ito, Tatsuo Kawamoto and Keiji Moriyama. Long-term Observations After Surgical Orthodontic Treatment For Mandibular Prognathism With Facial Asymmetry. International Seminar on Cleft Lip and/or Plate and Related Craniofacial Anomalies 2015.06.08 Tokyo

  17. 14. Liu S, Higashihori N, Moriyama K. Retinoic acid inhibits histone methyltransferase Whsc1 during palatogenesis. 第62回国際歯科研究学会日本支部会総会・学術大会 2014.12.04

  18. Higashihori N, Katayanagi M, Takada J, Moriyama K. Variation in tooth number and size in NTA patients. International Orthodontic Forum 2014.11.21

  19. Takahashi Y, Higashihori N, Komazaki Y, Takada J, Moriyama K. Examination of craniofacial morphology in tooth agenesis patients. 90th Congress of the European Orthodontic Society 2014.06.18

  20. 1. Kamata H, Fukuoka H, Shiga M, Higashihori N, Kawamoto T, Moriyama K. Three-dimensional analysis of mandibular morphology in patients with facial asymmetry and mandibular prognathism. The 45th Annual Scientific Congress of Korean Association of Orthodontists 2012.11.01

  21. Higashihori N, Nakayama Y, Fukuoka H, Kawamoto T, Moriyama K. Long-term stability of occlusion after sagittal split ramus osteotomy for mandibular prognathism. XIV International Symposium on Dentofacial Development and Function 2012.09.20

  22. Kataoka K, Ogawa T, Haruyama N, Kobayahsi Y, Higashihori N, Moriyama K. Post operative stability of maxillary intraoral distraction osteogenesis in cleft lip and palate patients. The 14th International Symposium on Dentofacial Development and Function. Beijing 2012.09.19

  23. Mikami T, Higashihori N, Fukuoka H, Kawamoto T, Moriyama K. Soft tissue profile changes following anterior segmental maxillary osteotomy in mandibular retrognathia patients. The 14th International Symposium on Dentofacial Development and Function 2012.09.19

  24. Kataoka K, Ogawa T, Baba Y, Higashihori N, Suzuki S, Moriyama K. Ultrasonographic monitoring for bony healing after maxillary distraction osteogenesis in an adult cleft lip and palate case. 9th European Craniofacial Congress 2011.09.14

  25. Higashihori N, Buchtová M, Richman JM. A role of TBX22 during avian frontonasal prominence morphogenesis. 第34回日本口蓋裂学会総会 2010.05.27

  26. Higashihori N, Lehnertz B, Rossi FM, Richman JM. G9a negatively regulates osteoblast differentiation. UBC Dentistry Research Day 2009.01.27

  27. Higashihori N, Buchtova M, Richman JM. Function of human TBX22 during chicken facial development. 86th General Session & Exhibition of the International Association of Dental Research 2008.07.02

  28. Higashihori N, Song Y-P, Richman JM. Regulation and Function of a BMP Receptor Antagonist in the Face. UBC Dentistry Research Day 2008.01.29

  29. Higashihori N, Funato N, Nakamura M, Ohyama K. Transcriptional regulation of p21Waf1/Cip1 by basic helix-loop-helix factors. 84th General Session & Exhibition of the International Association of Dental Research 2006.07.01

  30. Mukai K, Baba Y, Tsuji M, Ishizaki T, Higashihori N, Tetsumura A, Ohbayashi N, Kurabayashi T, Suzuki S, Ohyama K. Ultrasonographic observation after distraction osteogenesis in maxillary region. 84th General Session & Exhibition of the International Association of Dental Research 2006.07.01

  31. Ohkuma M, Higashihori N, Funato N, Nakamura M, Ohyama K. Regulation of Twist-1 expression in osteoblast differentiation. 84th General Session & Exhibition of the International Association of Dental Research 2006.07.01

  32. 73. Inoue MS, BabaY, Gereltzul E, Tsuji M, Shin I, Higashihori N, Ohkuma M, Ohyama K. A report of patient with 18q interstitial deletion and ring chromosome mosaicism. The 45th Annual Meeting of the Japanese Teratology Society 2005.07.14

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Awards & Honors 【 display / non-display 】

  • The 11th Asian Pacific Orthodontic Conference(APOC 2018) Posterboard Presentation 2nd Place Research(Hikita R, Higashihori N, Kadota C, Akiyama S, Takahashi Y, Ito Y, Moriyama K)，The Asian Pacific Orthodontic Society，2018.03

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