Personnel Information

写真a

HOSOYA Takamitsu


Job title

Professor

Birth date

1966

Laboratory Address

2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, Japan

Mail Address

The inquiry by e-mail is 《here

Homepage URL

https://chembiolab.sakura.ne.jp/Web-English/Home.html

Research Areas, Keywords

Organic Synthesis, Chemical Biology

Graduating School 【 display / non-display

  • Keio University, Faculty of Science and Engineering, Department of Chemistry, 1990.03, Graduated

Graduate School 【 display / non-display

  • Keio University, Graduate School, Division of Science and Engineering, Department of Chemistry, Master's Course, 1992.03, Completed

  • Keio University, Graduate School, Division of Science and Engineering, Department of Chemistry, Doctor's Course, 1995.03, Completed

Degree 【 display / non-display

  • Doctorate of Science, Keio University

Campus Career 【 display / non-display

  • 2012.04
    -
    Now
    Tokyo Medical and Dental University, Institute of Biomaterials and Bioengineering, Biomolecular Chemistry, Chemical Bioscience, Professor
  • 2012.04
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Life Science and Technology, Life Science and Technology, Chemical Bioscience, Professor
  • 2009.04
    -
    2012.03
    Tokyo Medical and Dental University, Laboratory of Chemical Biology, Graduate School of Biomedical Science, Tokyo Medical and Dental University, Professor

External Career 【 display / non-display

  • 2018.04
    -
    Now
    RIKEN, Center for Biosystems Dynamics Research (BDR), Laboratory for Chemical Biology, Team Leader
  • 2014.04
    -
    2018.03
    RIKEN, CLST Chemical Biology Team, Team Leader
  • 2013.01
    -
    2014.03
    RIKEN, CLST,
  • 2009.04
    -
    2011.03
    Tokyo Institute of Technology, Department of Biological Information, Graduate School of Bioscience and Biotechnology, Professor
  • 2007.04
    -
    2009.03
    Tokyo Institute of Technology, Department of Biological Information, Graduate School of Bioscience and Biotechnology, Associate Professor

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Research Areas 【 display / non-display

  • Organic chemistry

  • Synthetic chemistry

  • Biomolecular chemistry

  • Functional solid state chemistry

  • Bio-related chemistry

 

Published Papers & Misc 【 display / non-display

  • Matsuzawa T, Hosoya T, Yoshida S. Transition-Metal-Free Synthesis of N-Arylphenothiazines through an N- and S-Arylation Sequence. Org Lett. 2021.03; 23 (6): 2347-2352. ( PubMed, DOI )

  • Minoshima M, Uchida K, Nakamura Y, Hosoya T, Yoshida S. Acylalkylation of Arynes Generated from o-Iodoaryl Triflates with Hydrosilanes and Cesium Fluoride. Org Lett. 2021.03; 23 (5): 1868-1873. ( PubMed, DOI )

  • Nakajima H, Hazama Y, Sakata Y, Uchida K, Hosoya T, Yoshida S. Diverse diaryl sulfide synthesis through consecutive aryne reactions. Chem Commun. 2021.03; 57 (21): 2621-2624. ( PubMed, DOI )

  • M, Inoue A, Iida K, Denawa M, Kii I, Kadj F M Ni, Kishi T, Im D, Shimamura T, Onogi H, Yoshida S, Iwata S, Aoki J, Hosoya T, Hagiwara M. S1PR3–G12-biased agonist ALESIA targets cancer metabolism and promotes glucose starvation. Cell Chem Biol. 2021.02; ( PubMed, DOI )

  • Isoda M, Uetake Y, Takimoto T, Tsuda J, Hosoya T, Niwa T. Convergent Synthesis of Fluoroalkenes Using a Dual-Reactive Unit. J Org Chem. 2021.01; 86 (2): 1622-1632. ( PubMed, DOI )

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Conference Activities & Talks 【 display / non-display

  • Yoshida S, Uchida K, Minami Y, Hosoya T. Synthesis of Diverse Arenes via Aryne Intermediates Generated by C–C Bond Cleavage. 2019.11.09 Chino

  • Matsuzawa T, Yoshida S, Hosoya T. Facile Synthesis of N-Arylphenothiazines by Rearrangement of o-Sulfanylanilines. 27th International Society of Heterocyclic Chemistry Congress (27th ISHC Congress 2019) 2019.09.03 Kyoto

  • Nakamura Y, Yoshida S, Hosoya T. Synthesis of Diverse Heterocyclic Compounds via Au-Catalyzed Cyclization and Generation of Arynes. 27th International Society of Heterocyclic Chemistry Congress (27th ISHC Congress 2019) 2019.09.03 Kyoto

  • Niwa T, Isoda M, Uetake Y, Hosoya T. Convergent synthesis of fluoroalkenes using a bis-reactive unit. 19th European Symposium on Fluorine Chemistry 2019.08.30 Warsaw, Poland

  • Niwa T, Isoda M, Uetake Y, Hosoya T. Cu-Catalyzed Defluoroborylation for Facile Synthesis of Fluoroalkenes. 20th IUPAC International Symposium on Organometallic Chemistry Directed Towards Organic Synthesis (OMCOS 20) 2019.07.22 Heidelberg, Germany

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Patents 【 display / non-display

  • COMPOUND AND PHARMACEUTICAL COMPOSITION FOR NEUROPSYCHOLOGICAL DISORDER OR MALIGNANT TUMOR

    Patent Number: CA3006139

  • COMPOUND AND PHARMACEUTICAL COMPOSITION FOR NEUROPSYCHOLOGICAL DISORDER OR MALIGNANT TUMOR

    Patent Number: EP2881397

  • Coelenterazine analogues and coelenteramide analogues

    Patent Number: US 9075058

  • Process for producing substtuted benzo[f]imidazo[1,2-a]quinoxalin-3(11H)-ones

    Announcement Number: US 2015/0266833

  • Coelenterazine analogues and coelenteramide analogues

    Patent Number: US 9056840

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