Personnel Information

写真a

NAKASHIMA Tomoki


Job title

Professor

Mail Address

naka.csi@tmd.ac.jp

Campus Career 【 display / non-display

  • 2007.04
    -
    2013.03
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Matrix, Cell Signaling, Assistant Professor
  • 2013.04
    -
    2016.02
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Matrix, Cell Signaling, Associate Professor
  • 2016.03
    -
    2018.03
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Matrix, Cell Signaling, Professor
  • 2018.04
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Matrix, Cell Signaling, Professor

External Career 【 display / non-display

  • 2001.04
    -
    2002.04
    , Project Researcher

Academic Activity 【 display / non-display

  • 2017.08
    -
    Now
    Bone Research Board member

Research Areas 【 display / non-display

  • Molecular biology

  • Metabolomics

  • Pathological medical chemistry

  • General medical chemistry

  • Functional basic dentistry

Qualification Acquired 【 display / non-display

  • Pharmacist

 

Research Theme 【 display / non-display

  • Regulation mechanism of bone remodeling

Published Papers & Misc 【 display / non-display

  • Y Kameo, Y Miya, M Hayashi, T Nakashima, T Adachi. In silico experiments of bone remodeling explore metabolic diseases and their drug treatment. Sci Adv. 2020.03; 6 (10): eaax0938. ( PubMed, DOI )

  • Takehito Ono, Mikihito Hayashi, Fumiyuki Sasaki, Tomoki Nakashima. RANKL biology: bone metabolism, the immune system, and beyond. Inflamm Regen. 2020.02; 40 2. ( PubMed, DOI )

  • Fumiyuki Sasaki, Mikihito Hayashi, Yuki Mouri, Satoshi Nakamura, Taiji Adachi, Tomoki Nakashima. Mechanotransduction via the Piezo1-Akt pathway underlies Sost suppression in osteocytes. Biochem. Biophys. Res. Commun.. 2020.01; 521 (3): 806-813. ( PubMed, DOI )

  • Jing-Yi Xue, Zheng Wang, Satoshi Shinagawa, Hirofumi Ohashi, Nao Otomo, Nursel H Elcioglu, Tomoki Nakashima, Gen Nishimura, Shiro Ikegawa, Long Guo. TNFRSF11A-Associated Dysosteosclerosis: A Report of the Second Case and Characterization of the Phenotypic Spectrum. J. Bone Miner. Res.. 2019.10; 34 (10): 1873-1879. ( PubMed, DOI )

  • Mikihito Hayashi, Tomoki Nakashima, Noriko Yoshimura, Kazuo Okamoto, Sakae Tanaka, Hiroshi Takayanagi. Autoregulation of Osteocyte Sema3A Orchestrates Estrogen Action and Counteracts Bone Aging. Cell Metab.. 2019.03; 29 (3): 627-637.e5. ( PubMed, DOI )

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Conference Activities & Talks 【 display / non-display

  • 小野岳人、傳田良亮、権藤理夢、河崎万鈴、木下佑理、中島友紀. ケミカルライブラリーを用いた新規スクリーニング法による運動器疾患の治療薬探索. 第4回日本骨免疫学会 2018.06.24 沖縄

  • Tomoki Nakashima. Bone homeostasis and mechanomedicine. 第95回 日本生理学会 2018.03.29 高松

  • Tomoki Nakashima. Bone homeostasis and mechano-biology. The 94th Annual Meeting of the Physiological Society of Japan 2017.03.28 Hamamatsu

  • Tomoki Nakashima . Regulation of bone remodeling . 3nd Seoul Symposium on Bone Health KSBMR-JSBMR joint symposium 2015.05.27 Seoul

  • M. Hayashi, T. Nakashima, and H. Takayanagi. Regulation of bone metabolism by Semaphorin 3A derived from osteoblastlineage cells.. ASBMR 2014 Annual Meeting 2014.09.13

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Awards & Honors 【 display / non-display

  • IADR/AADR William J. Gies Award,International Association for Dental Research,2018.08