Campus Career 【 display / non-display 】

Campus Career 【 display / non-display 】

• 2007.04

  -

  2013.03

  Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Matrix， Cell Signaling， Assistant Professor
• 2013.04

  -

  2016.02

  Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Matrix， Cell Signaling， Associate Professor
• 2016.03

  -

  2018.03

  Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Matrix， Cell Signaling， Professor
• 2018.04

  -

  Now

  Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Matrix， Cell Signaling， Professor

External Career 【 display / non-display 】

External Career 【 display / non-display 】

• 2001.04

  -

  2002.04

  , Project Researcher

Academic Activity 【 display / non-display 】

Academic Activity 【 display / non-display 】

• 2017.08

  -

  Now

  Bone Research Board member

Research Areas 【 display / non-display 】

Research Areas 【 display / non-display 】

• Molecular biology

• Metabolomics

• Pathological medical chemistry

• General medical chemistry

• Functional basic dentistry

Qualification Acquired 【 display / non-display 】

Qualification Acquired 【 display / non-display 】

• Pharmacist

Research Theme 【 display / non-display 】

Research Theme 【 display / non-display 】

• Regulation mechanism of bone remodeling

  Keyword： Bone homeostasis
  

Published Papers & Misc 【 display / non-display 】

Published Papers & Misc 【 display / non-display 】

• Fumiyuki Sasaki, Mikihito Hayashi, Yuki Mouri, Satoshi Nakamura, Taiji Adachi, Tomoki Nakashima. Mechanotransduction via the Piezo1-Akt pathway underlies Sost suppression in osteocytes. Biochem. Biophys. Res. Commun.. 2019.11; ( PubMed, DOI )

• Jing-Yi Xue, Zheng Wang, Satoshi Shinagawa, Hirofumi Ohashi, Nao Otomo, Nursel H Elcioglu, Tomoki Nakashima, Gen Nishimura, Shiro Ikegawa, Long Guo. TNFRSF11A-Associated Dysosteosclerosis: A Report of the Second Case and Characterization of the Phenotypic Spectrum. J. Bone Miner. Res.. 2019.10; 34 (10): 1873-1879. ( PubMed, DOI )

• Mikihito Hayashi, Tomoki Nakashima, Noriko Yoshimura, Kazuo Okamoto, Sakae Tanaka, Hiroshi Takayanagi. Autoregulation of Osteocyte Sema3A Orchestrates Estrogen Action and Counteracts Bone Aging. Cell Metab.. 2019.03; 29 (3): 627-637.e5. ( PubMed, DOI )

• Masamu Inoue, Takehito Ono, Yoshitaka Kameo, Fumiyuki Sasaki, Takashi Ono, Taiji Adachi, Tomoki Nakashima. Forceful mastication activates osteocytes and builds a stout jawbone. Sci Rep. 2019.03; 9 (1): 4404. ( PubMed, DOI )

• Yusoon Kim, Mikihito Hayashi, Takehito Ono, Tetsuya Yoda, Hiroshi Takayanagi, Tomoki Nakashima. Suppression of hematopoietic cell kinase ameliorates the bone destruction associated with inflammation. Mod Rheumatol. 2018.11; 1-17. ( PubMed, DOI )

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Conference Activities & Talks 【 display / non-display 】

Conference Activities & Talks 【 display / non-display 】

• 小野岳人、傳田良亮、権藤理夢、河崎万鈴、木下佑理、中島友紀. ケミカルライブラリーを用いた新規スクリーニング法による運動器疾患の治療薬探索. 第4回日本骨免疫学会 2018.06.24 沖縄

• Tomoki Nakashima. Bone homeostasis and mechanomedicine. 第95回 日本生理学会 2018.03.29 高松

• Tomoki Nakashima. Bone homeostasis and mechano-biology. The 94th Annual Meeting of the Physiological Society of Japan 2017.03.28 Hamamatsu

• Tomoki Nakashima . Regulation of bone remodeling . 3nd Seoul Symposium on Bone Health KSBMR-JSBMR joint symposium 2015.05.27 Seoul

• M. Hayashi, T. Nakashima, and H. Takayanagi. Regulation of bone metabolism by Semaphorin 3A derived from osteoblastlineage cells.. ASBMR 2014 Annual Meeting 2014.09.13

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Awards & Honors 【 display / non-display 】

Awards & Honors 【 display / non-display 】

• IADR/AADR William J. Gies Award，International Association for Dental Research，2018.08