Campus Career 【 display / non-display 】

Campus Career 【 display / non-display 】

• 2007.04

  -

  2013.03

  Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Matrix， Cell Signaling， Assistant Professor
• 2013.04

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  2016.02

  Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Matrix， Cell Signaling， Associate Professor
• 2016.03

  -

  2018.03

  Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Matrix， Cell Signaling， Professor
• 2018.04

  -

  2020.06

  Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Matrix， Cell Signaling， Professor
• 2020.07

  -

  Now

  Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Matrix， Cell Signaling， Professor

External Career 【 display / non-display 】

External Career 【 display / non-display 】

• 2001.04

  -

  2002.04

  , Project Researcher

Academic Activity 【 display / non-display 】

Academic Activity 【 display / non-display 】

• 2017.08

  -

  Now

  Bone Research Board member

Research Areas 【 display / non-display 】

Research Areas 【 display / non-display 】

• Molecular biology

• Metabolomics

• Pathological medical chemistry

• General medical chemistry

• Functional basic dentistry

Qualification Acquired 【 display / non-display 】

Qualification Acquired 【 display / non-display 】

• Pharmacist

Research Theme 【 display / non-display 】

Research Theme 【 display / non-display 】

• Regulation mechanism of bone remodeling

  Keyword： Bone homeostasis
  

Published Papers & Misc 【 display / non-display 】

Published Papers & Misc 【 display / non-display 】

• Hayashi M, Ono T, Nakashima T.. Signaling in osteoblast differentiation. Encyclopedia of Bone Biology. 2020.07; 416-426.

• Yosuke Tsuchiya, Mikihito Hayashi, Katashi Nagamatsu, Takehito Ono, Masaki Kamakura, Takanori Iwata, Tomoki Nakashima. The key royal jelly component 10-hydroxy-2-decenoic acid protects against bone loss by inhibiting NF-κB signaling downstream of FFAR4. J. Biol. Chem.. 2020.07; ( PubMed, DOI )

• Y Kameo, Y Miya, M Hayashi, T Nakashima, T Adachi. In silico experiments of bone remodeling explore metabolic diseases and their drug treatment. Sci Adv. 2020.03; 6 (10): eaax0938. ( PubMed, DOI )

• Takehito Ono, Mikihito Hayashi, Fumiyuki Sasaki, Tomoki Nakashima. RANKL biology: bone metabolism, the immune system, and beyond. Inflamm Regen. 2020.02; 40 2. ( PubMed, DOI )

• Fumiyuki Sasaki, Mikihito Hayashi, Yuki Mouri, Satoshi Nakamura, Taiji Adachi, Tomoki Nakashima. Mechanotransduction via the Piezo1-Akt pathway underlies Sost suppression in osteocytes. Biochem. Biophys. Res. Commun.. 2020.01; 521 (3): 806-813. ( PubMed, DOI )

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Conference Activities & Talks 【 display / non-display 】

Conference Activities & Talks 【 display / non-display 】

• 小野岳人、傳田良亮、権藤理夢、河崎万鈴、木下佑理、中島友紀. ケミカルライブラリーを用いた新規スクリーニング法による運動器疾患の治療薬探索. 第4回日本骨免疫学会 2018.06.24 沖縄

• Tomoki Nakashima. Bone homeostasis and mechanomedicine. 第95回 日本生理学会 2018.03.29 高松

• Tomoki Nakashima. Bone homeostasis and mechano-biology. The 94th Annual Meeting of the Physiological Society of Japan 2017.03.28 Hamamatsu

• Tomoki Nakashima . Regulation of bone remodeling . 3nd Seoul Symposium on Bone Health KSBMR-JSBMR joint symposium 2015.05.27 Seoul

• M. Hayashi, T. Nakashima, and H. Takayanagi. Regulation of bone metabolism by Semaphorin 3A derived from osteoblastlineage cells.. ASBMR 2014 Annual Meeting 2014.09.13

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Awards & Honors 【 display / non-display 】

Awards & Honors 【 display / non-display 】

• IADR/AADR William J. Gies Award，International Association for Dental Research，2018.08