Personnel Information

写真a

INOUE Katarzyna Anna


Job title

Assistant Professor

Laboratory Address

Yushima 1-5-45, Bunkyo-ku, Tokyo 113-8549

Laboratory Phone number

+81-3-5803-5449

Laboratory Fax number

+81-3-5803-0187

Mail Address

The inquiry by e-mail is 《here

Research Areas, Keywords

tumor microevironment, heparan sulfate proteoglycan, extracellular matrix

Degree 【 display / non-display

  • Doctor of Engineering, Tokyo Institute of Technology

Campus Career 【 display / non-display

  • 1998.04
    -
    2007.03
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Matrix, Biochemistry, Research Associate
  • 2007.04
    -
    2021.03
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Matrix, Biochemistry, Assistant Professor
  • 2021.04
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, -, Department of Biochemistry, Assistant Professor

Academic Society Affiliations 【 display / non-display

  • Japanese Society for Biochemistry

  • the Japanese Cancer Association

  • Japanese Society for Carbohydrate Research

Academic Activity 【 display / non-display

  • 2013.10
    -
    Now
    Proteoglycan Forum committee member

Research Areas 【 display / non-display

  • Functional biochemistry

  • Cell biology

 

Research Theme 【 display / non-display

  • Role of TGF-β signals in tumor progression, 2016 - Now

  • Heparan sulfate proteoglycan and cellular logistics, 2002 - Now

Published Papers & Misc 【 display / non-display

  • Shingo Kodama, Katarzyna Α Podyma-Inoue, Toshihiro Uchihashi, Kyoko Kurioka, Hitomi Takahashi, Akinari Sugauchi, Kazuki Takahashi, Toshihiro Inubushi, Mikihiko Kogo, Susumu Tanaka, Tetsuro Watabe. Progression of melanoma is suppressed by targeting all transforming growth factor‑β isoforms with an Fc chimeric receptor. Oncol Rep. 2021.09; 46 (3): ( PubMed, DOI )

  • Shintaro Sakakitani, Katarzyna A Podyma-Inoue, Rina Takayama, Kazuki Takahashi, Mari Ishigami-Yuasa, Hiroyuki Kagechika, Hiroyuki Harada, Tetsuro Watabe. Activation of β2-adrenergic receptor signals suppresses mesenchymal phenotypes of oral squamous cell carcinoma cells. Cancer Science. 2021.01; 112 (1): 155-167. ( PubMed, DOI )

  • Kazuki Takahashi, Yuichi Akatsu, Katarzyna A Podyma-Inoue, Takehisa Matsumoto, Hitomi Takahashi, Yasuhiro Yoshimatsu, Daizo Koinuma, Mikako Shirouzu, Kohei Miyazono, Tetsuro Watabe. Targeting all transforming growth factor-β isoforms with an Fc chimeric receptor impairs tumor growth and angiogenesis of oral squamous cell cancer. J. Biol. Chem.. 2020.09; 295 (36): 12559-12572. ( PubMed, DOI )

  • Yoshimatsu Y, Wakabayashi I, Kimuro S, Takahashi N, Takahashi K, Kobayashi M, Maishi N, Podyma-Inoue KA, Hida K, Miyazono K, Watabe T. TNF-α enhances TGF-β-induced endothelial-to-mesenchymal transition via TGF-β signal augmentation. Cancer Science. 2020.07; 111 (7): 2385-2399. ( PubMed, DOI )

  • Yoshimatsu Y, Kimuro S, Pauty J, Takagaki K, Nomiyama S, Inagawa A, Maeda K, Podyma-Inoue KA, Kajiya K, Matsunaga YT, Watabe T. TGF-beta and TNF-alpha cooperatively induce mesenchymal transition of lymphatic endothelial cells via activation of Activin signals. PloS One. 2020.05; 15 (5): e0232356. ( PubMed, DOI )

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Books etc 【 display / non-display

  • Ippei Watari, Mona Aly Abbassy, Katarzyna Anna Podyma-Inoue and Takashi Ono. Major Topics in Type 1 Diabetes, Dr. Kenia Nunes (Ed.). InTech, 2015.11 Complication of Type 1 Diabetes in Craniofacial and Dental Hard Tissue (ISBN : 978-953-51-2204-3)

  • Masaki Yanagishita and Katarzyna A. Inoue (N. Taniguchi et al. Editors). Experimental Glycoscience: Glycobiology; N. Taniguchi et al. (Eds). Springer, 2008.08 Golgi and Lysosomal Disease: Degradation of hyaluronan and its disorder (ISBN : 978-4431779216)

  • Basic Biochemistry Manual 5: Lipids, Sugars, Glycoconjugates. 2000.12 (ISBN : 978-4-8079-11851)

Conference Activities & Talks 【 display / non-display

  • The mechanism of malignant transformation through oral cancer derived exosomes. 2021.12

  • Katarzyna A. Inoue, Kazuki Takahashi, Sakakitani Shintaro, Daizo Koinuma, Akinari Sugauchi, Maki Saito, Atsushi Kaida, Yasuhiro Yoshimatsu, Toshihiro Uchihashi, Masahiko Miura, Kohei Miyazono, Tetsuro Watabe. Activation of epithelial-mesenchymal transition program in oral cancer cells under TGF-β-induced cell cycle arrest. TGF-β Superfamily Conference: Signaling in Development and Disease (FASEB) 2021.07.20

  • Shintaro Sakakitani, Katarzyna A. Podyma-Inoue, Kazuki Takahashi, Hiroyuki Harada, Tetsuro Watabe. Inhibition of oral squamous carcinoma cell progression by β2-adrenergic receptor signals. The 85th Annual Meeting of the Japanese Stomatological Society, Japan 2020.12.04 Tokyo

  • Katarzyna A. Inoue, Shintaro Sakakitani, Kazuki Takahashi, Hiroyuki Harada, Tetsuro Watabe. Novel approach for treatment of oral squamous cell carcinoma. 第79回日本癌学会学術総会 2020.10.03 広島

  • Shintaro Sakakitani, Katarzyna A. Podyma-Inoue, Kazuki Takahashi, Hiroyuki Harada, Tetsuro Watabe. Inhibition of oral squamous carcinoma cell progression by targeting β2-adrenergic receptor signals. The 97th Annual Meeting of the Japanese Cancer Association 2020.10.01 Hiroshima

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Campus class subject 【 display / non-display

  • Molceular basis of the life and the cell: laboratory,2007 - Now

  • Molceular basis of the life and the cell: Extracellular matrix,2016 - Now

  • Molecular and Cellular Biology: Structure, function and turnover of extracellular matrix,2018 - Now

  • Nutrition and metabolism (metabolism of sugars, lipids and proteins),2016 - Now