Personnel Information

写真a

MICHI Yasuyuki


Job title

Associate Professor

Birth date

1972

Laboratory Phone number

+81-3-5803-5506

Laboratory Fax number

+81-3-5803-0198

Mail Address

The inquiry by e-mail is 《here》

Research Areas, Keywords

oral oncology angiogenesis lymphangiogenesis osteomyelitis

Field Introduction URL

https://www.tmd-osur.info/

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Graduating School 【 display / non-display 】

  • Tohoku University, Faculty of Dentistry, 1996, Graduated

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Graduate School 【 display / non-display 】

  • Tokyo Medical and Dental University, Graduate School, Division of Dental Research, oral and maxillofacial surgery, Doctor's Course, 2000, Completed

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Degree 【 display / non-display 】

  • Doctor of Philosophy, Tokyo Medical and Dental University

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Campus Career 【 display / non-display 】

  • 2007.04
    -
    2018.03
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Maxillofacial and Neck Reconstruction， Maxillofacial Surgery， Assistant Professor
  • 2018.04
    -
    2018.06
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Maxillofacial and Neck Reconstruction， Maxillofacial Surgery， Assistant Professor
  • 2018.07
    -
    2021.10
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Oral Health Sciences， Oral and Maxillofacial Surgery， Junior Associate Professor
  • 2018.07
    -
    2021.10
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Oral Health Sciences， Oral and Maxillofacial Surgery， Junior Associate Professor
  • 2021.11
    -
    2022.03
    Tokyo Medical and Dental University， Tokyo Medical and Dental University， Division of Clinical Dentistry， Department of Oral and Maxillofacial Surgery， Oral and Maxillofacial Surgery， Associate Professor
  • 2022.04
    -
    2022.05
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Oral Health Sciences， Oral and Maxillofacial Surgery， Associate Professor
  • 2022.06
    　
    　
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Oral Health Sciences， Oral and Maxillofacial Surgery， Associate Professor
  • 2022.07
    -
    Now
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Division of Oral Health Sciences， Department of Oral and Maxillofacial Surgical Oncology， Associate Professor

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External Career 【 display / non-display 】

  • 2003.04
    -
    2007.03
    , Dental Resident
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Research Areas 【 display / non-display 】

  • Surgical dentistry

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Qualification Acquired 【 display / non-display 】

  • Dentist

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Published Papers & Misc 【 display / non-display 】

  1. Kugimoto, T; Nishii, N; Oikawa, Y; Kuroshima, T; Hirai, H; Tomioka, H; Michi, Y; Kayamori, K; Sakamoto, J; Iwanaga, J; Tubbs, RS; Ikeda, T; Miura, M; Harada, H. Invasion of the bucco-mandibular space by oral squamous cell carcinoma: histopathological analysis of invasion pattern FRONTIERS IN ONCOLOGY. 2023.10; 13 1168376. ( PubMed, DOI )

  2. Ohyama Y, Yamashiro M, Michi Y, Uzawa N, Myo K, Sonoda I, Sumino J, Miura C, Mizutani M, Yamamoto D, Kayamori K, Yoda T. Determination of Significant Prognostic Factors for Maxillary Gingival Squamous Cell Carcinoma in 90 Cases. Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India. 2022.12; 74 (Suppl 3): 5930-5935. ( PubMed, DOI )

  3. Takuya Komiyama, Takeshi Kuroshima, Takehito Sugasawa, Shin-Ichiro Fujita, Yuta Ikami, Hideaki Hirai, Fumihiko Tsushima, Yasuyuki Michi, Kou Kayamori, Fumihiro Higashino, Hiroyuki Harada. High expression of Sam68 contributes to metastasis by regulating vimentin expression and a motile phenotype in oral squamous cell carcinoma. Oncol Rep. 2022.10; 48 (4): 183. ( PubMed, DOI )

  4. Yanamoto Souichi, Michi Yasuyuki, Otsuru Mitsunobu, Inomata Toru, Nakayama Hideki, Nomura Takeshi, Hasegawa Takumi, Yamamura Yoshiko, Yamada Shin-ichi, Kusukawa Jingo, Yamakawa Nobuhiro, Hasegawa On, Ueda Michihiro, Kitagawa Yoshimasa, Hiraki Akimitsu, Hasegawa Toshihiro, Ohiro Yoichi, Kobayashi Wataru, Asoda Seiji, Kobayashi Takanori, Iino Mitsuyoshi, Fukuda Masayuki, Ishibashi-Kanno Naomi, Kawaguchi Koji, Aijima Reona, Noguchi Kazuma, Okura Masaya, Tanaka Akira, Sugiura Tsuyoshi, Shintani Yukari, Yagihara Kazuhiro, Yamashiro Masashi, Ota Yoshihide, Miyazaki Akihiro, Takeshita Akinori, Kawamata Hitoshi, Hiroshi Iwabuchi, Uchida Kenichiro, Umeda Masahiro, Kurita Hiroshi, Kirita Tadaaki. Protocol for a multicentre, prospective observational study of elective neck dissection for clinically node-negative oral tongue squamous cell carcinoma (END-TC study) BMJ OPEN. 2022.09; 12 (9): e059615. ( PubMed, DOI )

  5. Noji Rika, Tohyama Kohki, Kugimoto Takuma, Kuroshima Takeshi, Hirai Hideaki, Tomioka Hirofumi, Michi Yasuyuki, Tasaki Akihisa, Ohno Kazuchika, Ariizumi Yosuke, Onishi Iichiroh, Suenaga Mitsukuni, Mori Takehiko, Okamoto Ryuichi, Yoshimura Ryoichi, Miura Masahiko, Asakage Takahiro, Miyake Satoshi, Ikeda Sadakatsu, Harada Hiroyuki, Kano Yoshihito. Comprehensive Genomic Profiling Reveals Clinical Associations in Response to Immune Therapy in Head and Neck Cancer CANCERS. 2022.07; 14 (14): ( PubMed, DOI )

  6. Kohei Okuyama, Yasuyuki Michi, Yoshihisa Kashima, Hirofumi Tomioka, Hideaki Hirai, Misaki Yokokawa, Yuko Yamagata, Takeshi Kuroshima, Yuriko Sato, Maiko Tsuchiya, Kou Kayamori, Tohru Ikeda, Hiroyuki Harada. Epithelial-Myoepithelial Carcinoma of the Minor Salivary Glands: Case Series with Comprehensive Review. Diagnostics (Basel). 2021.11; 11 (11): 2124. ( PubMed, DOI )

  7. Takeshi Kuroshima, Yusuke Onozato, Yu Oikawa, Toshimitsu Ohsako, Takuma Kugimoto, Hideaki Hirai, Hirofumi Tomioka, Yasuyuki Michi, Masahiko Miura, Ryoichi Yoshimura, Hiroyuki Harada. Prognostic impact of lingual lymph node metastasis in patients with squamous cell carcinoma of the tongue: a retrospective study. Sci Rep. 2021.10; 11 (1): 20535. ( PubMed, DOI )

  8. Kohei Okuyama, Souichi Yanamoto, Yasuyuki Michi, Eri Shibata, Maiko Tsuchiya, Misaki Yokokawa, Tomofumi Naruse, Hirofumi Tomioka, Takeshi Kuroshima, Hiroaki Shimamoto, Tohru Ikeda, Masahiro Umeda, Tetsuya Yoda, Hiroyuki Harada. Multicenter retrospective analysis of clinicopathological features and prognosis of oral tongue squamous cell carcinoma in adolescent and young adult patients. Medicine (Baltimore). 2021.10; 100 (41): e27560. ( PubMed, DOI )

  9. Aragaki Tadanobu, Tomomatsu Nobuyoshi, Michi Yasuyuki, Hosaka Hisashi, Fukai Yasuyuki, Iijima Misa, Yoda Tetsuya. ラムシルマブ関連口腔内化膿性肉芽腫　2症例報告(Ramucirumab-related Oral Pyogenic Granuloma: A Report of Two Cases) Internal Medicine. 2021.08; 60 (16): 2601-2605. ( ichushi )

  10. Shiba T, Watanabe T, Komatsu K, Koyanagi T, Nemoto T, Ohsugi Y, Michi Y, Katagiri S, Takeuchi Y, Ishihara K, Iwata T. Non-surgical treatment for periodontitis and peri-implantitis: longitudinal clinical and bacteriological findings-A case report with a 7-year follow-up evaluation. SAGE open medical case reports. 2021.07; 9 2050313X211029154. ( PubMed, DOI )

  11. Suga Takayuki, Tu Trang Thi Huyen, Takenoshita Miho, Mikuzuki Lou, Umezaki Yojiro, Shimamoto Hiroaki, Michi Yasuyuki, Hong Chaoli, Abiko Yoshihiro, Ikeda Tohru, Uzawa Narikazu, Harada Hiroyuki, Toyofuku Akira. Case Report: Hidden Oral Squamous Cell Carcinoma in Oral Somatic Symptom Disorder FRONTIERS IN PSYCHIATRY. 2021.04; 12 651871. ( PubMed, DOI )

  12. Fukawa Yuki, Sakamoto Kei, Kugimoto Takuma, Michi Yasuyuki, Harada Hiroyuki, Yamamoto Masahide, Kitagawa Masanobu, Ikeda Tohru, Yamamoto Kouhei. Nodular lymphocyte-predominant Hodgkin lymphoma involving the hard palate PATHOLOGY INTERNATIONAL. 2021.03; 71 (3): 213-215. ( PubMed, DOI )

  13. Aragaki T, Tomomatsu N, Michi Y, Hosaka H, Fukai Y, Iijima M, Yoda T. Ramucirumab-related Oral Pyogenic Granuloma: A Report of Two Cases. Internal medicine (Tokyo, Japan). 2021.03; ( PubMed, DOI )

  14. Shibata E, Morita KI, Kayamori K, Tange S, Shibata H, Harazono Y, Michi Y, Ikeda T, Harada H, Imoto I, Yoda T. Detection of novel fusion genes by next-generation sequencing-based targeted RNA sequencing analysis in adenoid cystic carcinoma of head and neck. Oral surgery, oral medicine, oral pathology and oral radiology. 2021.03; 132 (4): 426-433. ( PubMed, DOI )

  15. Baba Shunichi, Akashi Takumi, Kayamori Kou, Ohuchi Tomoyuki, Ogawa Ikuko, Kubota Nobuhisa, Nakano Keisuke, Nagatsuka Hitoshi, Hasegawa Hiromasa, Matsuzaka Kenichi, Tomii Shohei, Uchida Keisuke, Katsuta Noriko, Sekiya Takahiro, Ando Noboru, Miura Keiko, Ishibashi Hironori, Ariizumi Yousuke, Asakage Takahiro, Michi Yasuyuki, Harada Hiroyuki, Sakamoto Kei, Eishi Yoshinobu, Okubo Kenichi, Ikeda Tohru. Homeobox transcription factor engrailed homeobox 1 is a possible diagnostic marker for adenoid cystic carcinoma and polymorphous adenocarcinoma PATHOLOGY INTERNATIONAL. 2021.02; 71 (2): 113-123. ( PubMed, DOI )

  16. Terauchi Masahiko, Michi Yasuyuki, Hirai Hideaki, Sugiyama Kentaro, Wada Akane, Harada Hiroyuki, Yoda Tetsuya. Prognostic factors in mucoepidermoid carcinoma of the minor salivary glands: A single-center retrospective study ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY. 2021.02; 131 (2): 209-216. ( PubMed, DOI )

  17. Kayamori Kou, Tsuchiya Maiko, Michi Yasuyuki, Kuribayashi Ami, Mikami Toshinari, Sakamoto Kei, Yoda Tetsuya, Ikeda Tohru. Primordial odontogenic tumor occurred in the maxilla with unique calcifications and its crucial points for differential diagnosis PATHOLOGY INTERNATIONAL. 2021.01; 71 (1): 80-87. ( DOI )

  18. Oikawa Yu, Michi Yasuyuki, Tsushima Fumihiko, Tomioka Hirofumi, Mochizuki Yumi, Kugimoto Takuma, Osako Toshimitsu, Nojima Hitomi, Yokokawa Misaki, Kashima Yoshihisa, Harada Hiroyuki. Management of retropharyngeal lymph node metastasis in oral cancer ORAL ONCOLOGY. 2019.12; 99 104471. ( PubMed, DOI )

  19. Mochizuki Yumi, Harada Hiroyuki, Oyama Jun, Sakamoto Kei, Michi Yasuyuki, Kuroshima Takeshi, Kugimoto Takuma. Metastatic gastric adenocarcinoma of the tongue with initial symptoms of glossodynia CURRENT PROBLEMS IN CANCER. 2019.12; 43 (6): 100481. ( PubMed, DOI )

  20. Nakazato Keiichiro, Mogushi Kaoru, Kayamori Kou, Tsuchiya Maiko, Takahashi Ken-Ichiro, Sumino Jun, Michi Yasuyuki, Yoda Tetsuya, Uzawa Narikazu. Glucose metabolism changes during the development and progression of oral tongue squamous cell carcinomas ONCOLOGY LETTERS. 2019.08; 18 (2): 1372-1380. ( PubMed, DOI )

  21. Kurohara K, Michi Y, Yukimori A, Yamaguchi S. The glomus tumor resorbed bone and teeth in the mandible: a case report Head and Face Medicine. 2018.09; 14 (18): ( DOI )

  22. Kurohara Kazuto, Michi Yasuyuki, Yukimori Akane, Yamaguchi Satoshi. The glomus tumor resorbed bone and teeth in the mandible: a case report HEAD & FACE MEDICINE. 2018.09; 14 (1): 18. ( PubMed, DOI )

  23. Matsui T, Okada T, Kawada K, Okuda M, Ogo T, Nakajima Y, Kume Y, Ryotokuji T, Hoshino A, Tokairin Y, Michi Y, Harada H, Nakajima Y, Kawano T. Detection of Second Primary Malignancies of the Esophagus and Hypophraynx in Oral Squamous Cell Carcinoma Patients. Laryngoscope investigative otolaryngology. 2018.08; 3 (4): 263-267. ( PubMed, DOI )

  24. Okuyama K, Yamashiro M, Kaida A, Kawamata A, Mizutani M, Michi Y, Uzawa N, Yano T, Tohyama R, Yamaguchi S. Does a Vascularized Fibula Free Bone Grafted Immediately After Hemimandibulectomy in a Child Grow or Relapse During Adolescence? The Journal of craniofacial surgery. 2018.07; 29 (5):

  25. Michikawa C, Izumo T, Sumino J, Morita T, Ohyama Y, Michi Y, Uzawa N. Small size of metastatic lymph nodes with extracapsular spread greatly impacts treatment outcomes in oral squamous cell carcinoma patients International Journal of Oral and Maxillofacial Surgery. 2018.07; 47 (7): 830-835. ( DOI )

  26. Yamaga Emi, Toriihara Akira, Nakamura Shin, Asai Sakurako, Fujioka Tomoyuki, Yoshimura Ryoichi, Michi Yasuyuki, Harada Hiroyuki, Tateishi Ukihide. Clinical usefulness of 2-deoxy-2-[F-18]fluoro-D-glucose-positron emission tomography/ computed tomography for assessing early oral squamous cell carcinoma (cT1-2N0M0) JAPANESE JOURNAL OF CLINICAL ONCOLOGY. 2018.07; 48 (7): 633-639. ( PubMed, DOI )

  27. Michikawa C., Izumo T., Sumino J., Morita T., Ohyama Y., Michi Y., Uzawa N.. Small size of metastatic lymph nodes with extracapsular spread greatly impacts treatment outcomes in oral squamous cell carcinoma patients INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY. 2018.07; 47 (7): 830-835. ( PubMed, DOI )

  28. Okuyama Kohei, Yamashiro Masashi, Kaida Atsushi, Kawamata Aya, Mizutani Miho, Michi Yasuyuki, Uzawa Narikazu, Yano Tomoyuki, Tohyama Rei, Yamaguchi Satoshi. Does a Vascularized Fibula Free Bone Grafted Immediately After Hemimandibulectomy in a Child Grow or Relapse During Adolescence? JOURNAL OF CRANIOFACIAL SURGERY. 2018.07; 29 (5): E444-E449. ( PubMed, DOI )

  29. YUSOON KIM, KOHEI OKUYAMA, YASUYUKI MICHI, YOSHIO OHYAMA, NARIKAZU UZAWA, SATOSHI YAMAGUCHI. Potential factors influencing the development of oral tongue squamous cell carcinoma in young mature patients: Lingual position of the mandibular second molar and narrow tongue space ONCOLOGY LETTERS. 2017.12; 14 (6): 7339-7343. ( DOI )

  30. マハムド・エルバシュティ , アメル・アスウェヘリー , 服部 麻里子, 隅田 由香, 道 泰之, 鵜澤 成一, 山口 聡, 原田 浩之, 谷口 尚. 上顎切除患者に対する顎顔面補綴治療上の考慮事項に関する外科医の意識調査(Surgeons' Awareness of the Considerations for Prosthetic Rehabilitation in Maxillectomy Patients) 顎顔面補綴. 2017.12; 40 (2): 28-36. ( ichushi )

  31. J Sumino, N Uzawa, Y Ohyama, Y Michi, A Kawamata, M Mizutani, M Yamashiro. First signs of late-presenting cervical lymph node metastasis in oral cancers during follow-up. Int J Oral Maxillofac Surg. 2017.06; 46 (6): 676-681. ( PubMed, DOI )

  32. 加地 博一, 丸山 緑子, 丸山 史人, 芝 多佳彦, 渡辺 孝康, 郷田 瑛, 村瀬 一典, 道 泰之, 竹内 康雄, 和泉 雄一, 山口 聰, 中川 一路. 細菌活動性から顕在化するインプラント周囲炎および歯周炎の疾患特異的な細菌群集内の共起構造 口腔病学会雑誌. 2017.03; 84 (1): 25-36. ( ichushi )

  33. 加地 博一, 丸山 緑子, 丸山 史人, 芝 多佳彦, 渡辺 孝康, 郷田 瑛, 村瀬 一典, 道 泰之, 竹内 康雄, 和泉 雄一, 山口 聰, 中川 一路. 細菌活動性から顕在化するインプラント周囲炎および歯周炎の疾患特異的な細菌群集内の共起構造(Active Microbiota Show Specific Correlationships in Peri-implantitis and Periodontitis) 口腔病学会雑誌. 2017.03; 84 (1): 25-36. ( ichushi )

  34. Yasuyuki Michi, Miho Suzuki, Kazuto Kurohara, Kiyoshi Harada. A case of hemangiopericytoma of the soft palate with articulate disorder and dysphagia. Int J Oral Sci. 2013.06; 5 (2): 111-114. ( PubMed, DOI )

  35. Asumi Honda-Uezono, Atsushi Kaida, Yasuyuki Michi, Kiyoshi Harada, Yoshiki Hayashi, Yoshio Hayashi, Masahiko Miura. Unusual expression of red fluorescence at M phase induced by anti-microtubule agents in HeLa cells expressing the fluorescent ubiquitination-based cell cycle indicator (Fucci). Biochem. Biophys. Res. Commun.. 2012.11; 428 (2): 224-229. ( PubMed, DOI )

  36. Kazuto Kurohara, Narikazu Uzawa, Yasuyuki Michi, Kiyoshi Harada. A neuroendocrine tumor in the maxilla. J. Oral Maxillofac. Surg.. 2012.11; 70 (11): e679-e682. ( PubMed, DOI )

  37. Erika Oue, Ji-Won Lee, Kei Sakamoto, Tadahiro Iimura, Kazuhiro Aoki, Kou Kayamori, Yasuyuki Michi, Masashi Yamashiro, Kiyoshi Harada, Teruo Amagasa, Akira Yamaguchi. CXCL2 synthesized by oral squamous cell carcinoma is involved in cancer-associated bone destruction. Biochem. Biophys. Res. Commun.. 2012.08; 424 (3): 456-461. ( PubMed, DOI )

  38. Kihara T, Ichikawa S, Yonezawa T, Lee JW, Akihisa T, Woo JT, Michi Y, Amagasa T, Yamaguchi A. Acerogenin A, a natural compound isolated from Acer nikoense Maxim, stimulates osteoblast differentiation through bone morphogenetic protein action. Biochem Biophys Res Commun. 2011.03; 406 (2): 211-217. ( PubMed, DOI )

  39. Aragaki T, Michi Y, Katsube K, Uzawa N, Okada N, Akashi T, Amagasa T, Yamaguchi A, Sakamoto K. Comprehensive keratin profiling reveals different histopathogenesis of keratocystic odontogenic tumor and orthokeratinized odontogenic cyst. Hum Pathol. 2010.12; 41 (12): 1718-1725. ( PubMed, DOI )

  40. Maeda K, Yamashiro M, Michi Y, Suzuki T, Ohyama Y, Okada N, Amagasa T. Effective staining method with iodine for leukoplakia and lesions surrounding squamous cell carcinomas of the tongue assessed by colorimetric analysis. J Med Dent Sci. 2009.12; 56 (4): 123-130. ( PubMed )

  41. Michi Y, Morita I, Amagasa T, Murota S. Human oral squamous cell carcinoma cell lines promote angiogenesis via expression of vascular endothelial growth factor and upregulation of KDR/flk-1 expression in endothelial cells. Oral Oncol. 2000.01; 36 (1): 81-88. ( PubMed )

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Conference Activities & Talks 【 display / non-display 】

  1. 釘本 琢磨, 清水 六花, 西井 直人, 大迫 利光, 及川 悠, 黒嶋 雄志, 平井 秀明, 富岡 寛文, 道 泰之, 栢森 高, 池田 通, 原田 浩之. 口腔扁平上皮癌におけるBucco-mandibular space進展例の臨床病理学的検討. 日本癌治療学会学術集会抄録集 2022.10.01

  2. 原田 浩之, 及川 悠, 大迫 利光, 釘本 琢磨, 平井 秀明, 富岡 寛文, 島本 裕彰, 道 泰之. 口腔癌に対する治療戦略　口腔癌の新たな治療戦略. 日本癌治療学会学術集会抄録集 2021.10.01

  3. 釘本 琢磨, 及川 悠, 大迫 利光, 黒嶋 雄志, 平井 秀明, 富岡 寛文, 島本 裕彰, 道 泰之, 原田 浩之. 口腔扁平上皮癌の周術期に血栓症を発症した4例. 日本癌治療学会学術集会抄録集 2021.10.01

  4. 島本 裕彰, 及川 悠, 大迫 利光, 釘本 琢磨, 黒嶋 雄志, 平井 秀明, 富岡 寛文, 道 泰之, 原田 浩之. 口腔扁平上皮癌レベルIV、V転移症例の検討. 日本癌治療学会学術集会抄録集 2021.10.01

  5. Eri SHIBATA, Kei-ichi MORITA, Yasuyuki MICHI, Tetsuya YODA. A case of Mammary Analogue Secretory Carcinoma in Salivary Duct of Parotid Gland. 13th Asian Congress on oral and maxillofacial surgery 2018.11.08 台北

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