Personnel Information

写真a

KURATA Morito


Job title

Junior Associate Professor

Mail Address

The inquiry by e-mail is 《here

Research Areas, Keywords

Leukemia, oncogene, drug resistance, CRISPR screening

Profile

My interest is the mechanism of tumorigenesis and drug resistance in leukemia. CRISPR screening is a powerful tool to clarify the new mechanisms of drug resistance. Comprehensive screening is one promising approach for identifying new oncogenic targets of cancer cell survival.

Graduating School 【 display / non-display

  • Fukui Medical University, Faculty of Medicine, 2003.03, Graduated

Graduate School 【 display / non-display

  • Tokyo Medical and Dental University, Doctor's Course, 2007.03, Completed

Campus Career 【 display / non-display

  • 2007.04
    -
    2013.03
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Advanced Therapeutic Sciences, Comprehensive Pathology, Assistant Professor
  • 2013.04
    -
    2013.09
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Advanced Therapeutic Sciences, Comprehensive Pathology, Junior Associate Professor
  • 2016.09
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Advanced Therapeutic Sciences, Comprehensive Pathology, Junior Associate Professor

External Career 【 display / non-display

  • 2013.10
    -
    2016.09
    University of Minnesota, Masonic Cancer Center, Visiting Associate Professor / Research Scholar

Research Areas 【 display / non-display

  • Pathological medical chemistry

  • Experimental pathology

Qualification Acquired 【 display / non-display

  • Doctor

 

Published Papers & Misc 【 display / non-display

  • Kurata M, Onishi I, Takahara T, Yamazaki Y, Ishibashi S, Goitsuka R, Kitamura D, Takita J, Hayashi Y, Largaesapda DA, Kitagawa M, Nakamura T. C/EBPβ induces B-cell acute lymphoblastic leukemia and cooperates with BLNK mutations. Cancer science. 2021.10; ( PubMed, DOI )

  • Yamamoto Akiko, Kurata Morito, Onishi Iichiroh, Sugita Keisuke, Matsumura Miwa, Ishibashi Sachiko, Ikeda Masumi, Yamamoto Kouhei, Kitagawa Masanobu. CRISPR screening identifies M1AP as a new MYC regulator with a promoter-reporter system PEERJ. 2020.05; 8 e9046. ( PubMed, DOI )

  • Morito Kurata, Kouhei Yamamoto, Branden S Moriarity, Masanobu Kitagawa, David A Largaespada. CRISPR/Cas9 library screening for drug target discovery. J. Hum. Genet.. 2018.02; 63 (2): 179-186. ( PubMed, DOI )

  • Morito Kurata, Natalie K Wolf, Walker S Lahr, Madison T Weg, Mitchell G Kluesner, Samantha Lee, Kai Hui, Masano Shiraiwa, Beau R Webber, Branden S Moriarity. Highly multiplexed genome engineering using CRISPR/Cas9 gRNA arrays. PLoS ONE. 2018.09; 13 (9): e0198714. ( PubMed, DOI )

  • Morito Kurata, Susan K Rathe, Natashay J Bailey, Natalie K Aumann, Justine M Jones, G Willemijn Veldhuijzen, Branden S Moriarity, David A Largaespada. Using genome-wide CRISPR library screening with library resistant DCK to find new sources of Ara-C drug resistance in AML. Sci Rep. 2016.11; 6 36199. ( PubMed, DOI )

display all >>

Conference Activities & Talks 【 display / non-display

  • Largaespada David A., Kurata Morito, Pope Emily A., Beckmann Pauli J., Larson Jon D., Shu Jingmin, Temiz Nuri A., Sarver Aaron L., Seshagiri Somasekar. RNA sequencingにより、transposon mutagenesisに誘発されるマウス腫瘍の"molecular pathology"が明らかになる(RNA sequencing reveals the "molecular pathology" of mouse tumors induced by transposon mutagenesis). 日本病理学会会誌 2021.03.01

  • 倉田 盛人, 大西 威一郎, 山本 浩平, 北川 昌伸. CRISPR libraryを用いたNRAS発現調整可能THP-1細胞株によるシグナル解析. 日本癌学会総会記事 2020.10.01

  • 田口 登和子, 山本 浩平, 木脇 祐子, 大西 威一郎, 倉田 盛人, 山本 正英, 北川 昌伸. びまん性大細胞性リンパ腫においてSECISBP2はセレノプロテインを調整する新規の予後予測因子になりうる. 日本癌学会総会記事 2020.10.01

  • 川出 玄二, 山本 浩平, 立澤 杏奈, 矢内 雅恵, 倉田 盛人, 北川 昌伸. 肝細胞癌におけるGPX4発現の臨床病理学的検討. 日本癌学会総会記事 2020.10.01

  • 大西 威一郎, 倉田 盛人, 山本 浩平, 木村 剛, 岸田 晶夫, 北川 昌伸. 脱細胞化骨を用いた、ヒト骨髄微小環境再構築の試み. 日本癌学会総会記事 2020.10.01

display all >>

 

Social Contribution 【 display / non-display

  • Guest editor,Journal of Molecular Sciences (ISSN 1422-0067),2021.08 - Now