Graduating School 【 display / non-display 】
-
Kyoto University, Faculty of Pharmaceutical Science, 1988, Graduated
Campus Career 【 display / non-display 】
-
2015.04-NowTokyo Medical and Dental University, Institute of Biomaterials and Bioengineering, Biomolecular Chemistry, Medicinal Chemistry, Professor
-
2014.04-2015.03Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Life Science and Technology, Life Science and Technology, Molecular Biomedicine, Professor
-
2014.01-2015.03Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Advanced Therapeutic Sciences, Medicinal Chemistry, Professor
-
2015.04-NowTokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Life Science and Technology, Life Science and Technology, Medicinal Chemistry, Professor
Published Papers & Misc 【 display / non-display 】
-
Miller SE, Tsuji K, Abrams RPM, Burke TR Jr, Schneider JP. Uncoupling the Folding-Function Paradigm of Lytic Peptides to Deliver Impermeable Inhibitors of Intracellular Protein-Protein Interactions. Journal of the American Chemical Society. 2020.11; ( PubMed, DOI )
-
Takuya Kobayakawa, Kento Ebihara, Kohei Tsuji, Takuma Kawada, Masayuki Fujino, Yuzuna Honda, Nami Ohashi, Tsutomu Murakami & Hirokazu Tamamura. Bivalent HIV-1 fusion inhibitors based on peptidomimetics. Bioorganic & medicinal chemistry. 2020.10; 28 (24): 115812. ( PubMed, DOI )
-
Daisuke Matsumoto, Hirokazu Tamamura & Wataru Nomura. A cell cycle-dependent CRISPR-Cas9 activation system based on an anti-CRISPR protein shows improved genome editing accuracy COMMUNICATIONS BIOLOGY. 2020.10; 3 1-10. ( PubMed, DOI )
-
Tsuji K, Hymel D, Burke TR. A new genre of fluorescence recovery assay to evaluate polo-like kinase 1 ATP-competitive inhibitors. Analytical methods : advancing methods and applications. 2020.09; 12 (36): 4418-4421. ( PubMed, DOI )
-
Tsuji K, Owusu KB, Kobayakawa T, Wang R, Fujino M, Kaneko M, Yamamoto N, Murakami T, Tamamura H. Exploratory studies on CA-15L, an anti-HIV active HIV-1 capsid fragment. Bioorganic & medicinal chemistry. 2020.06; 28 (11): 115488. ( PubMed, DOI )
Books etc 【 display / non-display 】
-
The Frontier of Peptide Drug Discovery. 2019.05 (ISBN : 978-4-7813-1417-4)
-
Hirokazu Tamamura, Takuya Kobayakawa, Nami Ohashi. Mid-size Drugs Based on Peptides and Peptidomimetics. 2018.01 (ISBN : 978-981-10-7691-6)
-
Ohashi N, Tamamura H. “Peptide-derived mid-sized anti-HIV agents” In “Amino Acids, Peptides and Proteins,” ed. by Maxim Ryadnov and Ferenc Hudecz, The Royal Society of Chemistry, Cambridge CB4 0WF, UK, vol. 41. 2017.01
-
Takuya Kobayakawa, Tetsuo Narumi, Hirokazu Tamamura. tereoselective Synthesis of Chloroalkene Dipeptide Isosteres Utilizing Organocopper Reagents. The Japanese Peptide Society, 2016.03
-
Takano H, Narumi T, Nomura W, Furuta T, Tamamura H. Development of 8-Azacoumarin-4-ylmethyl-type Photolabile Protecting Groups Based on Amide-Alkene Isosterism. in "Peptide Science 2014," ed. by Akira Otaka, The Japanese Peptide Society, Osaka. 2015
Conference Activities & Talks 【 display / non-display 】
-
Hirokazu Tamamura. Bioimaging of GPCR dimers and its application to molecular probes for cancer cells. A3 Foresight & 5 Star Alliance Joint Workshop on Organic/Inorganic Hybrid Nano Materials and Bio Imaging 2020.12.03 online
-
Kaho Matsumoto, Takeo Kuwata, Zahid Hasan, Yu Kaku, Shashwata Biswas, Shokichi Takahama, Hirokazu Tamamura and Shuzo Matsushita. The CD4 mimetic compound YIR-821-mediated enhancement of the neutralization activities of plasma IgG against autologous isolates in vitro.. 21st Kumamoto AIDS Seminar 2020.11.11 online
-
Kofi Baffour-Awuah Owusu, Kohei Tsuji, Rongyi Wang, Takuya Kobayakawa, Moemi Kaneko, Tsutomu Murakami, Hirokazu Tamamura. Exploratory studies on the development of anti-HIV-1 peptides based on HIV-1 capsid fragments. The 57th Japanese Peptide Symposium 2020.11.10 online
-
Kohei Tsuji, David Hyme, Buyong Ma, Ruth Nussinov, Hirokazu Tamamura,Terrence R. Burke, Jr.. Development of bivalent inhibitors of polo-like kinase 1 with great affinity enhancement. The 57th Japanese Peptide Symposium 2020.11.10 online
-
Wataru Nomura, Takumi Kamimura, Takuya Kobayakawa, Hirokazu Tamamura. Endogenous protein expression imaging by fluorogenic ZIP tag-probe system. The 57th Japanese Peptide Symposium 2020.11.10 online