Personnel Information



Job title


Laboratory Address

2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062

Research Areas, Keywords

Biosniffers, Wearable sensors, Ubiquitous biomonitoring, Phsyical measurement, Non-invasive monitoring

Graduating School 【 display / non-display

  • Toyohashi University of Technology, Faculty of Engineering, 1983.03, Graduated

Graduate School 【 display / non-display

  • The University of Tokyo, Graduate School, Division of Engineering, Department of Advanced Interdisciplinary Studies (AIS), Doctor's Course, 1994.09, Completed

  • Toyohashi University of Technology, Graduate School, Division of Engineering, Master's Course, 1985.03, Completed

Degree 【 display / non-display

  • Ph.D., The University of Tokyo

  • Master of Engineering, Toyohashi University of Technology

  • Bachelor of Engineering, Toyohashi University of Technology

Campus Career 【 display / non-display

  • 2003.09
    Tokyo Medical and Dental University, Institute of Biomaterials and Bioengineering, Medical Devices, Biomedical Devices and Instrumentation, Professor
  • 2003.09
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Professor
  • 2013.04
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Life Science and Technology, Life Science and Technology, Biomedical Devices and Instrumentation, Professor
  • 2014.04
    Tokyo Medical and Dental University, Deputy Director

External Career 【 display / non-display

  • 2003.09
    , Professor

Research Areas 【 display / non-display

  • Biomedical engineering/Biomaterial science and engineering

  • Nano/Microsystems

  • Perceptual information processing

  • Analytical chemistry

  • Biofunction/Bioprocess

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Published Papers & Misc 【 display / non-display

  • Toma K, Iwasaki K, Arakawa T, Iwasaki Y, Mitsubayashi K. Sensitive and selective methanol biosensor using two-enzyme cascade reaction and fluorometry for non-invasive assessment of intestinal bacteria activity. Biosensors & bioelectronics. 2021.03; 181 113136. ( PubMed, DOI )

  • Koji Toma, Masato Tsujii, Takahiro Arakawa, Kohji Mitsubayashi. Dual-target gas-phase biosensor (bio-sniffer) for assessment of lipid metabolism from breath acetone and isopropanol Sensors and Actuators B: Chemical. 2021.02; 329 129260. ( DOI )

  • Koji Toma, Chisato Kishikawa, Takahiro Arakawa, Kohji Mitsubayashi. Reusable surface plasmon resonance immunosensor for temporal information of protein biomarkers Sensors and Materials. 2021.01; 33 251-260. ( DOI )

  • Koji Mizukoshi Takahiro Arakawa Kohji Mitsubayashi. Convenience biosensing approach of lactic acid in stratum corneum for skin care assessment Skin Research and Technology. 2020.07; 26 (4): 455-464.

  • Takahiro Arakawa, Takashi Aota, Kenta Iitani, Koji Toma, Iwasaki Y, Kohji Mitsubayash. Skin ethanol gas measurement system with a biochemical gas sensor and gas concentrator toward monitoring of blood volatile compounds Talanta. 2020.05; 115 887-895. ( DOI )

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Books etc 【 display / non-display

  • Odor-Sensing Technologies. 2020.08

  • K. Toma, T. Arakawa, K. Mitsubayashi. IMMUNOSENSORS. Royal Society of Chemistry, 2019.08 Rapid and Repeated Measurement of Mite Allergens Using a Surface Acoustic Wave (SAW) Immunosensor (ISBN : 978-1-78801-437-3)

  • Kohji Mitsubayashi, Osamu Niwa, Yuko Ueno. Chemical, Gas, and Biosensors for Internet of Things and Related Applications. Elsevier, 2019.07 (ISBN : ISBN: 9780128154090)

  • Kohji Mitsubayashi, Koji Toma, Takahiro Arakawa. Cavitas bio/chemical sensors for internet of things in healthcare, Chemical, gas, and biosensors for internet of things and related applications. Elsevier, 2019.06

  • Takahiro Arakawa, Koji Toma, Kohji Mitsubayashi. Bio-sniffer and sniff-cam, Chemical, gas, and biosensors for internet of things and related applications. Elsevier, 2019.06

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Conference Activities & Talks 【 display / non-display

  • Kohji Mitsubayashi. Bio-fluorometric gas sensing and imaging of human volatiles (Bio-sniffer & Sniff-cam). 8th International Conference on Nanoscience and Nanotechnology (ICONN 2020) 2020.02.12 Brisbane, Australia

  • Toma K, Oishi K, Kato M, Kurata K, Yoshimura N, Arakawa T, Yatsuda H, Mitsubayashi K. Precipitation-amplified surface acoustic wave immunosensor for senstive semi-continuous measurement of airborne mite allergens. Bio4Apps 2019 2019.12.18 Kagoshima, Japan

  • Arakawa T, Ohishi T, Tomoto K, Toma K, Mitsubayashi K. Mouthguard biosensor (cavitas sensor) toward monitoring of salivary glucose in oral cavity. Bio4Apps 2019 2019.12.18 Kagoshima, Japan

  • Kohji Mitsubayashi. Novel biosensing approaches for preemptive medicine. 8th International Conference on BioSensors, BioElectronics, BioMedical Devices, BioMEMS/NEMS, & Applications 2019 (Bio4Apps2019). 2019.12.18 Kagoshima, Japan

  • Kohji Mitsubayashi. Gas-Phase Biosensors (Bio-Sniffer & Sniff-Cam) for Human Volatile Chemicals. 17th International Conference on Biomedical Engineering (ICBME) 2019 2019.12.11 NUS, Singapore

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Patents 【 display / non-display

  • Method of determining authenticity and watermark reader

    Patent Number: S.N. 11/073854


    Patent Number: US. SERIAL NO. 10/235,070, Sept. 4, 2002

Awards & Honors 【 display / non-display

  • 2020 PROSE Award (Chemistry and Physics Category) by the Association of American Publishers,The Association of American Publishers,2020.02

  • 10th International Conference on Molecular Electronics & BioElectronics,2019.06

  • Best Poster Award, Bio4Apps2018/2019 (Arakawa T),2018.01

  • Best Poster Award, Bio4Apps2018/2019 (Ye M),2018.01

  • BEST PRESENTATION AWARD, ICBDID 2017 : 19th International Conference on Biomedical Device and Instrumentation Development,2017.03

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Others 【 display / non-display

  • "Mulling over the aromas of wine", American Chemical Society NEWS,2017.07

    Acetaldehyde is frequently found in a lot of places and foods, such as fruits, vegetables and human saliva. When present in high amounts in wine, it produces an unpleasant odor and affects the fermentation process. Therefore, it is important for winemakers to monitor the acetaldehyde levels, which can vary with temperature, pH and oxygen concentrations. Current methods involve trained experts, long processing times and complex equipment. Kohji Mitsubayashi and colleagues propose a sensitive, versatile detector that is more selective than its predecessors.

  • Implanted Flexible Neural Prostheses and MEMS by Dr. Chengkuo Lee, 190th IBB Seminar,2017.05

    Implanted flexible neural interfaces and MEMS devices currently become popular because they are considered as the viable solution to realize implanted prostheses for novel applications such as human-machine interface and electroceuticals.

  • Biomimetic Sensors: An Alternative to Conventional Biosensors, Prof. Thierry Noguer, 184th IBB Seminar ,2016.12

    Thie seminar will more specifically focus on our experience for designing biomimetic receptors such as aptamers and molecularly-imprinted polymers, as possible alternatives to classical bioreceptors.


Campus class subject 【 display / non-display

  • Bio-Intelligence Science

  • Biomedical Engineering,2004 - Now

  • Biomedical Device Science and Engineering,2015 - Now

  • Nanobiotechnology,2011 - 2017

  • Advanced Biosensing Devices,2018 - Now

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Social Contribution 【 display / non-display

  • Detecting Disease With "Sniff-Cam",Technology Networks,Technology Networks,2019.08.01

  • Simple, accurate, and fast: the new "sniff-cam" disease detector,NEWS Medical Life Science,NEWS Medical Life Science,2019.08.01

  • Sniff-cam' to detect disease by analyzing bad breath,Science Daily,Science Daily,2019.07.31

  • Sniff-cam' to detect disease, , ,2019.07.31

  • Cork Dork,Peguin Books,2018.09.30