Personnel Information

写真a

SHIBUYA Hiroshi


Job title

Professor

Mail Address

shibuya.mcb@mri.tmd.ac.jp

Graduating School 【 display / non-display

  • University of Tsukuba, Second Cluster of College, 1983.03, Graduated

Graduate School 【 display / non-display

  • University of Tsukuba, Graduate School, Division of Environmental Science, Master's Course, 1985.03, Completed

  • Osaka University, Graduate School, Division of Natural Science, Doctor's Course, 1990.03, Completed

Campus Career 【 display / non-display

  • 2000.09
    -
    Now
    Tokyo Medical and Dental University, Medical Research Institute, Advanced Molecular Medicine, Molecular Cell Biology, Professor
  • 2014.04
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Life Science and Technology, Life Science and Technology, Molecular Cell Biology, Professor
  • 2017.04
    -
    2018.03
    Tokyo Medical and Dental University, Board Member, Deputy Director
  • 2018.04
    -
    2020.03
    Tokyo Medical and Dental University, Board Member, Vice President
 

Published Papers & Misc 【 display / non-display

  • Nishita M., Nishikaku I., Yoshida E., Kamizaki K., Shibuya H., Matsumoto K., Minami Y.. Roil promotes invasion of lung adenocarcinoma cells through small GTPase Rif-mediated filopodia formation MOLECULAR BIOLOGY OF THE CELL. 2018.12; 29 (26): 231.

  • Sato A, Shibuya H.. Glycogen synthase kinase 3ß functions as a positive effector in the WNK signaling pathway. PLoS One. 2018.03; 13 e0193204.

  • Toshiyasu Goto, Junhei Matsuzawa, Shun-Ichiro Iemura, Tohru Natsume, Hiroshi Shibuya. WDR26 is a new partner of Axin1 in the canonical Wnt signaling pathway. FEBS Lett.. 2016.05; 590 (9): 1291-1303. ( PubMed, DOI )

  • Takashi Fukuzono, Strahil Iv Pastuhov, Okinobu Fukushima, Chun Li, Ayuna Hattori, Shun-Ichiro Iemura, Tohru Natsume, Hiroshi Shibuya, Hiroshi Hanafusa, Kunihiro Matsumoto, Naoki Hisamoto. Chaperone complex BAG2-HSC70 regulates localization of Caenorhabditis elegans leucine-rich repeat kinase LRK-1 to the Golgi. Genes Cells. 2016.04; 21 (4): 311-324. ( PubMed, DOI )

  • Isao Kii, Yuto Sumida, Toshiyasu Goto, Rie Sonamoto, Yukiko Okuno, Suguru Yoshida, Tomoe Kato-Sumida, Yuka Koike, Minako Abe, Yosuke Nonaka, Teikichi Ikura, Nobutoshi Ito, Hiroshi Shibuya, Takamitsu Hosoya, Masatoshi Hagiwara. Selective inhibition of the kinase DYRK1A by targeting its folding process. Nat Commun. 2016; 7 11391. ( PubMed, DOI )

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Conference Activities & Talks 【 display / non-display

  • Michiru Nishita, Koki Kamizaki, Ikumi Nishikaku, Hiroshi Shibuya, Kunio Matsumoto, Yasuhiro Minami. Ror1 signaling through Dvl and Rif promotes invasion of lung adenocarcinoma cells.. ASCB(米国細胞生物学会) 2019.12

  • Shimizu N, Ishitani S, Sato A, Shibuya H, Ishitani T. Hipk2 and PP1c-mediated dephosphorylation of Dishevelled sustains Wnt signal transduction. 11th International Conference on Zebrafish Development and Genetics 2014.06.27 Madison, Wisconsin, USA