Personnel Information

写真a

YOSHIDA Masayuki


Job title

Professor

Birth date

1963

Laboratory Address

1-5-45, Yushima, Bunkyo-ku, Tokyo, 113-8519

Mail Address

The inquiry by e-mail is 《here

Research Areas, Keywords

Genetic Medicine, Vascular Biology, Atherosclerosis, Research Ethics

Field Introduction URL

生命倫理研究センター

 

東京医科歯科大学遺伝子診療科

 

東京医科歯科大学吉田研究室

 

東京医科歯科大学遺伝カウンセリングコース

Graduating School 【 display / non-display

  • Tokyo Medical and Dental University, Faculty of Medicine, School of Medicine, 1988, Graduated

Degree 【 display / non-display

  • PhD, Tokyo Medical and Dental University

Campus Career 【 display / non-display

  • 2014.10
    -
    2017.03
    Tokyo Medical and Dental University, Research and Industry-University Alliance Organization, Life Science and Bioethics Research Center, Professor
  • 2007.09
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Public Health, Life Sciences and Bioethics, Professor
  • 2010.04
    -
    Now
    Tokyo Medical and Dental University, (Old Organization)Medical Hospital, Hospital Departments, Department of Internal Medicine, Medical Genetics, Medical Genetics, Head
  • 2017.04
     
     
    Tokyo Medical and Dental University, Institute of Research, Research Facility Cluster, Life Science and Bioethics Research Center, Professor
  • 2017.05
    -
    2020.09
    Tokyo Medical and Dental University, Institute of Research, Research Facility Cluster, Life Science and Bioethics Research Center, Professor
  • 2020.10
    -
    Now
    Tokyo Medical and Dental University, Institute of Research, Research Facility Cluster, Life Science and Bioethics Research Center, Professor

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Academic Society Affiliations 【 display / non-display

  • Japanese Atherosclerosis Society

  • Japanese Society of Human Genetics

  • Japanese Circulation Society

  • Japanese Vascular Biology and Medicine Organization

Academic Activity 【 display / non-display

  • Japnese Vascular Biology Organization (executive board member)
  • Japanese Society for Biorheology (executive board member)Liaison Association of Medical School's Ethics Committees executive board member)
  • Japanese Circulation Society (board-certified member)
  • Japanese Society of Gerontology (board-certified member)
  • Japanese Atherosclerosis Society (councilor)
  • Japanese Society of Human Genetics (councilor)

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Research Areas 【 display / non-display

  • Genetics

  • Genome biology

  • Philosophy and ethics

  • Cardiology

  • Life, health and medical informatics

  • Cell biology

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Published Papers & Misc 【 display / non-display

  1. Osaka M, Deushi M, Aoyama J, Funakoshi T, Ishigami A, Yoshida M. High-Fat Diet Enhances Neutrophil Adhesion in LDLR-Null Mice Via Hypercitrullination of Histone H3. JACC. Basic to translational science. 2021.06; 6 (6): 507-523. ( PubMed, DOI )

  2. Yamashita M, Tomoda T, Mizuo A, Isoda T, Egawa M, Yoshida M, Toki T, Kudo K, Terui K, Ito E, Morio T, Takagi M. Transient erythroblastopenia due to a GATA1 variant in an infant female. Pediatric blood & cancer. 2024.03; 71 (3): e30834. ( PubMed, DOI )

  3. Egawa M, Ikeda M, Miyasaka N, Harada-Shiba M, Yoshida M. Physicians' Perspective Toward Hypertensive Disorders of Pregnancy and Future Cardiovascular Diseases in Japan. Journal of atherosclerosis and thrombosis. 2024.02; ( PubMed, DOI )

  4. Okamura T, Tsukamoto K, Arai H, Fujioka Y, Ishigaki Y, Koba S, Ohmura H, Shoji T, Yokote K, Yoshida H, Yoshida M, Deguchi J, Dobashi K, Fujiyoshi A, Hamaguchi H, Hara M, Harada-Shiba M, Hirata T, Iida M, Ikeda Y, Ishibashi S, Kanda H, Kihara S, Kitagawa K, Kodama S, Koseki M, Maezawa Y, Masuda D, Miida T, Miyamoto Y, Nishimura R, Node K, Noguchi M, Ohishi M, Saito I, Sawada S, Sone H, Takemoto M, Wakatsuki A, Yanai H. Japan Atherosclerosis Society (JAS) Guidelines for Prevention of Atherosclerotic Cardiovascular Diseases 2022. Journal of atherosclerosis and thrombosis. 2023.12; ( PubMed, DOI )

  5. Egawa Makiko, Kanda Eiichiro, Ohtsu Hiroshi, Nakamura Tomohiro, Yoshida Masayuki. 日本人中高年女性において妊娠高血圧症候群は心血管疾患と関連する(Hypertensive Disorders of Pregnancy are Associated with Cardiovascular Disease in Middle- and Older-Aged Japanese Women) Journal of Atherosclerosis and Thrombosis. 2023.10; 30 (10): 1420-1426. ( ichushi )

  6. Yogi A, Iemura R, Nakatani H, Takasawa K, Gau M, Yamauchi T, Yoshida M, Moriyama K, Ishii T, Hosokawa S, Yamada M, Suzuki H, Kosaki K, Kashimada K, Morio T. BMP2 is a potential causative gene for isolated dextrocardia situs solitus. European journal of medical genetics. 2023.08; 66 (9): 104820. ( PubMed, DOI )

  7. Egawa M, Kanda E, Ohtsu H, Nakamura T, Yoshida M. Number of Children and Risk of Cardiovascular Disease in Japanese Women: Findings from the Tohoku Medical Megabank. Journal of atherosclerosis and thrombosis. 2023.02; 30 (2): 131-137. ( PubMed, DOI )

  8. Egawa Makiko, Kanda Eiichiro, Ohtsu Hiroshi, Nakamura Tomohiro, Yoshida Masayuki. 日本人女性における子どもの数と心血管疾患のリスク 東北メディカル・メガバンクの知見(Number of Children and Risk of Cardiovascular Disease in Japanese Women: Findings from the Tohoku Medical Megabank) Journal of Atherosclerosis and Thrombosis. 2023.02; 30 (2): 131-137. ( ichushi )

  9. Egawa M, Kanda E, Ohtsu H, Nakamura T, Yoshida M. Hypertensive Disorders of Pregnancy are Associated with Cardiovascular Disease in Middle- and Older-Aged Japanese Women. Journal of atherosclerosis and thrombosis. 2023.01; 30 (10): 1420-1426. ( PubMed, DOI )

  10. Kaneko S, Sakura F, Tanita K, Shimbo A, Nambu R, Yoshida M, Umetsu S, Inui A, Okada C, Tsumura M, Yamada M, Suzuki H, Kosaki K, Ohara O, Shimizu M, Morio T, Okada S, Kanegane H. Janus kinase inhibitors ameliorate clinical symptoms in patients with STAT3 gain-of-function. Immunotherapy advances. 2023; 3 (1): ltad027. ( PubMed, DOI )

  11. Kirino S, Suzuki M, Ogawa T, Takasawa K, Adachi E, Gau M, Takahashi K, Ikeno M, Yamada M, Suzuki H, Kosaki K, Moriyama K, Yoshida M, Morio T, Kashimada K. Clinical report: Chronic liver dysfunction in an individual with an AMOTL1 variant. European journal of medical genetics. 2022.11; 65 (11): 104623. ( PubMed, DOI )

  12. Niwano T, Hosoya T, Kadowaki S, Toyofuku E, Naruto T, Shimizu M, Ohnishi H, Koike R, Morio T, Imai K, Yoshida M, Yasuda S. An adult case of suspected A20 haploinsufficiency mimicking polyarteritis nodosa. Rheumatology (Oxford, England). 2022.11; 61 (11): e337-e340. ( PubMed, DOI )

  13. Ito S, Hashimoto H, Yamakawa H, Kusumoto D, Akiba Y, Nakamura T, Momoi M, Komuro J, Katsuki T, Kimura M, Kishino Y, Kashimura S, Kunitomi A, Lachmann M, Shimojima M, Yozu G, Motoda C, Seki T, Yamamoto T, Shinya Y, Hiraide T, Kataoka M, Kawakami T, Suzuki K, Ito K, Yada H, Abe M, Osaka M, Tsuru H, Yoshida M, Sakimura K, Fukumoto Y, Yuzaki M, Fukuda K, Yuasa S. The complement C3-complement factor D-C3a receptor signalling axis regulates cardiac remodelling in right ventricular failure. Nature communications. 2022.09; 13 (1): 5409. ( PubMed, DOI )

  14. Aoyama Jiro, Osaka Mizuko, Deushi Michiyo, Hosoya Shoichi, Ishigami Akihito, Maehara Taketoshi, Yoshida Masayuki. CXCL1刺激によるPAD4の細胞質移行はPDIA1のシトルリン化を介して好中球の接着を亢進する(CXCL1-Triggered PAD4 Cytoplasmic Translocation Enhances Neutrophil Adhesion through Citrullination of PDIA1) Journal of Atherosclerosis and Thrombosis. 2022.09; 29 (9): 1307-1318. ( ichushi )

  15. Inoue R, Nishi H, Osaka M, Yoshida M, Nangaku M. Neutrophil Protein Kinase R Mediates Endothelial Adhesion and Migration by the Promotion of Neutrophil Actin Polymerization. Journal of immunology (Baltimore, Md. : 1950). 2022.05; 208 (9): 2173-2183. ( PubMed, DOI )

  16. Yoshida M. More Than Clean, Sustainable, and Renewable Energy Source: New Therapeutic Role for Hydrogen? JACC. Basic to translational science. 2022.02; 7 (2): 162-163. ( PubMed, DOI )

  17. Ishisaka Y, Nosaka N, Mishima Y, Masuda T, Nagashima M, Tanaka Y, Yamamoto K, Yoshida M, Shigemitsu H. COVID-19 case of ventilator-induced lung injury on extracorporeal membrane oxygenation: Physicians' clinical struggle and ethical conflict in a novel pandemic. Clinical case reports. 2021.12; 9 (12): e05223. ( PubMed, DOI )

  18. Aoyama J, Osaka M, Deushi M, Hosoya S, Ishigami A, Maehara T, Yoshida M. CXCL1-Triggered PAD4 Cytoplasmic Translocation Enhances Neutrophil Adhesion through Citrullination of PDIA1. Journal of atherosclerosis and thrombosis. 2021.12; 29 (9): 1307-1318. ( PubMed, DOI )

  19. Ebana Y, Yang SH, Yokono M, Yoshida M. Establishment of the Certified Research Ethics Professionals: An Ethical Review Expert -Translated in English from Japanese Version. JMA journal. 2021.10; 4 (4): 405-408. ( PubMed, DOI )

  20. Ebana Yusuke, Yang Sou Hee, Yokono Megumu, Yoshida Masayuki. Establishment of the Certified Research Ethics Professionals: An Ethical Review Expert: Translated in English from Japanese Version(和訳中) JMA Journal. 2021.10; 4 (4): 405-408. ( ichushi )

  21. Masuda T, Uchimido R, Nosaka N, Akiyama H, Kamisato A, Yoshida M. Concerns in Methodology for Self-Administered Questionnaire: Needs for Involvement of Social Scientists. Chest. 2021.07; 160 (1): e92-e93. ( PubMed, DOI )

  22. Ikeda Sadakatsu, Kudo Ryo, Yamashita Yamato, Noji Rika, Yokobori Jyunko, Ohki Mika, Takamine Eriko, Kobayashi Yumi, Egawa Makiko, Ebana Yusuke, Kimura Koichiro, Yokoyama Kohta, Onishi Iichiro, Takemoto Akira, Kirimura Susumu, Kinowaki Yuko, Tanimoto Kosuke, Miya Fuyuki, Kano Yoshihito, Yoshida Masayuki, Miyake Satoshi. Clinical utility of multi-disciplinary expert panel discussion in precision cancer medicine ANNALS OF ONCOLOGY. 2021.07; 32 S287. ( DOI )

  23. Dewan SMR, Osaka M, Deushi M, Yoshida M. Complement C5a-triggered differentiated HL-60 stimulates migration of THP-1 monocytic leukocytes via secretion of CCL2. FEBS open bio. 2021.03; ( PubMed, DOI )

  24. Nagaoka E, Arai H, Ugawa T, Masuda T, Ochiai K, Tamaoka M, Kurashima N, Oi K, Fujiwara T, Yoshida M, Shigemitsu H, Otomo Y. Efficacy of multidisciplinary team approach with extracorporeal membrane oxygenation for COVID-19 in a low volume ECMO center. Artificial organs. 2021.03; ( PubMed, DOI )

  25. Dewan Syed Masudur Rahman, Osaka Mizuko, Deushi Michiyo, Yoshida Masayuki. C5a-stimulated Neutrophil-like Differentiated HL-60 Induced Migration of Monocytic THP-1 through the Secretion of MCP-1(和訳中) 日本循環器学会学術集会抄録集. 2021.03; 85回 OE029-5. ( ichushi )

  26. Tsuru Hiromi, Osaka Mizuko, Yoshida Masayuki. Complement Factor D Facilitates the Development of Fatty Liver under Long-term but not Short-term High-fat Diet-feeding Conditions(和訳中) 日本循環器学会学術集会抄録集. 2021.03; 85回 OE113-3. ( ichushi )

  27. Yamashita S, Masuda D, Akishita M, Arai H, Asada Y, Dobashi K, Egashira K, Harada-Shiba M, Hirata K, Ishibashi S, Kajinami K, Kinoshita M, Kozaki K, Kuzuya M, Ogura M, Okamura T, Sato K, Shimano H, Tsukamoto K, Yokode M, Yokote K, Yoshida M. Guidelines on the Clinical Evaluation of Medicinal Products for Treatment of Dyslipidemia. Journal of atherosclerosis and thrombosis. 2020.11; 27 (11): 1246-1254. ( PubMed, DOI )

  28. Yamashita Shizuya, Masuda Daisaku, Akishita Masahiro, Arai Hidenori, Asada Yujiro, Dobashi Kazushige, Egashira Kensuke, Harada-Shiba Mariko, Hirata Kenichi, Ishibashi Shun, Kajinami Kouji, Kinoshita Makoto, Kozaki Koichi, Kuzuya Masafumi, Ogura Masatsune, Okamura Tomonori, Sato Kayoko, Shimano Hitoshi, Tsukamoto Kazuhisa, Yokode Masayuki, Yokote Koutaro, Yoshida Masayuki. 脂質異常症治療に使用される医薬品の臨床評価に関するガイドライン(Guidelines on the Clinical Evaluation of Medicinal Products for Treatment of Dyslipidemia) Journal of Atherosclerosis and Thrombosis. 2020.11; 27 (11): 1246-1254. ( ichushi )

  29. Tsuru H, Osaka M, Hiraoka Y, Yoshida M. HFD-induced hepatic lipid accumulation and inflammation are decreased in Factor D deficient mouse. Scientific reports. 2020.10; 10 (1): 17593. ( PubMed, DOI )

  30. Egawa M, Hara K, Ikeda M, Kono E, Miyashita S, Miyasaka N, Inaji M, Maehara T, Yoshida M. Role of obstetricians in promoting pregnancy-related knowledge among women with epilepsy in Japan. Epilepsy & behavior : E&B. 2020.10; 111 107176. ( PubMed, DOI )

  31. Nouchi R, Aihara H, Arie F, Asashima M, Daida H, Fudano J, Fujiwara Y, Fushiki S, Geller RJ, Hatano K, Homma T, Kimura M, Kuroki T, Miki K, Morita I, Nitta K, Shinohara A, Siomi MC, Yoshida M, Ichikawa I. Toward global standardization of conducting fair investigations of allegations of research misconduct. Accountability in research. 2020.08; 27 (6): 327-346. ( PubMed, DOI )

  32. Egawa M, Hara K, Ikeda M, Yoshida M. Questionnaire dataset: Attitude of epileptologists and obstetricians to pregnancy among women with epilepsy. Data in brief. 2020.08; 31 105948. ( PubMed, DOI )

  33. Terui-Kohbata H, Egawa M, Yura K, Yoshida M. Knowledge and attitude of hereditary breast cancer among Japanese university female students. Journal of human genetics. 2020.07; 65 (7): 591-599. ( PubMed, DOI )

  34. Dewan Syed Masudur Rahman, Deushi Michiyo, Osaka Mizuko, Yoshida Masayuki. C5aは好中球様細胞へ分化したHL60においてNF-κBシグナル伝達経路を介してMCP-1発現を上昇させる(C5a Elevates MCP-1 Expression in Neutrophil-like Differentiated HL60 via NF-κ B Signaling Pathway) 日本循環器学会学術集会抄録集. 2020.07; 84回 OE122-6. ( ichushi )

  35. Tsuru Hiromi, Osaka Mizuko, Yoshida Masayuki. 高脂肪食誘発性脂肪肝の発症において補体D因子が果たす重要な役割(Critical Role of Complement Factor D in the Development of High-fat Diet-induced Fatty Liver) 日本循環器学会学術集会抄録集. 2020.07; 84回 PE28-2. ( ichushi )

  36. Yoshida Masayuki. 血栓症研究 最新情報 高脂肪食誘発性アテローム性血管炎の進行におけるvital NETosisの関与(Thrombosis Research -Update- Involvement of Vital NETosis in the Progression of High Fat Diet-induced Atherogenic Vascular Inflammation) 日本循環器学会学術集会抄録集. 2020.07; 84回 Symposium9-4. ( ichushi )

  37. Terui-Kohbata Hiroko, Egawa Makiko, Yura Kei, Yoshida Masayuki. 日本の女子大生における遺伝性乳癌に関する知識と態度(Knowledge and attitude of hereditary breast cancer among Japanese university female students) Journal of Human Genetics. 2020.07; 65 (7): 591-599. ( ichushi )

  38. Dewan Syed Masudur Rahman, Deushi Michiyo, Osaka Mizuko, Yoshida Masayuki. 分化したHL60のC5aによる刺激はMCP-1依存的経路を介してTHP-1走化性を誘導する(C5a stimulation of differentiated HL60 induces THP-1 chemotaxis via MCP-1 dependent pathway) 日本動脈硬化学会総会プログラム・抄録集. 2020.07; 52回 268. ( ichushi )

  39. Yoshida Hiroshi, Tada Hayato, Ito Kumie, Kishimoto Yoshimi, Yanai Hidekatsu, Okamura Tomonori, Ikewaki Katsunori, Inagaki Kyoko, Shoji Tetsuo, Bujo Hideaki, Miida Takashi, Yoshida Masayuki, Kuzuya Masafumi, Yamashita Shizuya. 健康な日本人における血清非コレステロールステロールの男女別基準値(Reference Intervals of Serum Non-Cholesterol Sterols by Gender in Healthy Japanese Individuals) Journal of Atherosclerosis and Thrombosis. 2020.05; 27 (5): 409-417. ( ichushi )

  40. Higashijima Y, Matsui Y, Shimamura T, Nakaki R, Nagai N, Tsutsumi S, Abe Y, Link VM, Osaka M, Yoshida M, Watanabe R, Tanaka T, Taguchi A, Miura M, Ruan X, Li G, Inoue T, Nangaku M, Kimura H, Furukawa T, Aburatani H, Wada Y, Ruan Y, Glass CK, Kanki Y. Coordinated demethylation of H3K9 and H3K27 is required for rapid inflammatory responses of endothelial cells. The EMBO journal. 2020.04; 39 (7): e103949. ( PubMed, DOI )

  41. Fukaishi T, Minami I, Masuda S, Miyachi Y, Tsujimoto K, Izumiyama H, Hashimoto K, Yoshida M, Takahashi S, Kashimada K, Morio T, Kosaki K, Maezawa Y, Yokote K, Yoshimoto T, Yamada T. A case of generalized lipodystrophy-associated progeroid syndrome treated by leptin replacement with short and long-term monitoring of the metabolic and endocrine profiles. Endocrine journal. 2020.02; 67 (2): 211-218. ( PubMed, DOI )

  42. Fukaishi Takahiro, Minami Isao, Masuda Seizaburo, Miyachi Yasutaka, Tsujimoto Kazutaka, Izumiyama Hajime, Hashimoto Koshi, Yoshida Masayuki, Takahashi Sayako, Kashimada Kenichi, Morio Tomohiro, Kosaki Kenjiro, Maezawa Yoshiro, Yokote Koutaro, Yoshimoto Takanobu, Yamada Tetsuya. レプチン補充療法および代謝・内分泌プロファイルの短期・長期モニタリングを施行された全身性脂肪萎縮症関連早老症の1例(A case of generalized lipodystrophy-associated progeroid syndrome treated by leptin replacement with short and long-term monitoring of the metabolic and endocrine profiles) Endocrine Journal. 2020.02; 67 (2): 211-218. ( ichushi )

  43. Doshida Y, Sano H, Iwabuchi S, Aigaki T, Yoshida M, Hashimoto S, Ishigami A. Age-associated changes in the transcriptomes of non-cultured adipose-derived stem cells from young and old mice assessed via single-cell transcriptome analysis. PloS one. 2020; 15 (11): e0242171. ( PubMed, DOI )

  44. Nishi H., Inoue R., Osaka M., Inoue T., Yoshida M., Nangaku M.. Neutrophil interferon-induced, double-stranded RNA-activated protein kinase (EIF2AK2) mediates vascular adhesion and transmigration in non-viral inflammatory disease EUROPEAN JOURNAL OF IMMUNOLOGY. 2019.10; 49 582.

  45. Yoshida H, Tada H, Ito K, Kishimoto Y, Yanai H, Okamura T, Ikewaki K, Inagaki K, Shoji T, Bujo H, Miida T, Yoshida M, Kuzuya M, Yamashita S. Reference Intervals of Serum Non-Cholesterol Sterols by Gender in Healthy Japanese Individuals. Journal of atherosclerosis and thrombosis. 2019.09; ( PubMed, DOI )

  46. Takahashi Kenta, Oshima Noriko, Nakamura Reiko, Iwahara Yuki, Wakana Kimio, Yoshida Masayuki, Miyasaka Naoyuki. Detection of hereditary gynecologic cancer by screening and risk assessment using questionnaires in gynecological outpatient clinic(和訳中) The Journal of Obstetrics and Gynaecology Research. 2019.08; 45 (8): 1682. ( ichushi )

  47. Dewan Syed Masudur Rahman, Shiraishi Orie, Deushi Michiyo, Tani Mariko, Osaka Mizuko, Yoshida Masayuki. C5aによる好中球β2インテグリン活性化はPKCδの膜移行に関与する(C5a-induced β2 integrin activation in neutrophils involves membrane translocation of PKC δ) 日本動脈硬化学会総会プログラム・抄録集. 2019.07; 51回 2-P. ( ichushi )

  48. Hirayama Atsushi, Yamashita Shizuya, Ruzza Andrea, Inomata Hyoe, Cyrille Marcoli, Lu Chen, Hamer Andrew W., Yoshida Masayuki, Kiyosue Arihiro, Teramoto Tamio. Long-Term Treatment With Evolocumab Among Japanese Patients - Final Report of the OSLER Open-Label Extension Studies CIRCULATION JOURNAL. 2019.05; 83 (5): 971-977. ( PubMed, DOI )

  49. Nohara Atsushi, Otsubo Yoshihiko, Yanagi Koji, Yoshida Masayuki, Ikewaki Katsunori, Harada-Shiba Mariko, Jurecka Agnieszka. ホモ接合型家族性高コレステロール血症(HoFH)の日本人患者におけるロミタピドの安全性と有効性 AEGR-733-301長期延長試験の結果(Safety and Efficacy of Lomitapide in Japanese Patients with Homozygous Familial Hypercholesterolemia(HoFH): Results from the AEGR-733-301 Long-Term Extension Study) Journal of Atherosclerosis and Thrombosis. 2019.04; 26 (4): 368-377. ( ichushi )

  50. Hirayama Atsushi, Yamashita Shizuya, Ruzza Andrea, Inomata Hyoe, Cyrille Marcoli, Hamer Andrew W., Yoshida Masayuki, Kiyosue Arihiro, Teramoto Tamio. 日本人患者におけるエボロクマブによる長期治療 OSLER非盲検延長試験の最終報告(Long-Term Treatment With Evolocumab Among Japanese Patients: Final Report of the OSLER Open-Label Extension Studies) Circulation Journal. 2019.04; 83 (5): 971-977. ( ichushi )

  51. Hirayama Atsushi, Yamashita Shizuya, Ruzza Andrea, Inomata Hyoe, Cyrille Marcoli, Hamer Andrew, Yoshida Masayuki, Kiyosue Arihiro, Teramoto Tamio. 日本人患者集団におけるevolocumabのOSLER非盲検延長試験の5年間の最終報告(Final 5-Year Report of the OSLER Open-Label Extension Studies of Evolocumab in the Japanese Patient Population) 日本循環器学会学術集会抄録集. 2019.03; 83回 LBCT2-4. ( ichushi )

  52. Takahashi Kenta, Oshima Noriko, Nakamura Reiko, Iwahara Yuki, Wakana Kimio, Yoshida Masayuki, Miyasaka Naoyuki. 婦人科外来部門における問診票スクリーニングを用いた遺伝性腫瘍の検出(Detection of hereditary gynecologic cancer by screening and risk assessment using questionnaires in gynecological outpatient clinic) 日本産科婦人科学会雑誌. 2019.02; 71 (臨増): S-196. ( ichushi )

  53. Kameyama Noriko, Maruyama Chizuko, Kitagawa Fuyuha, Nishii Kazunobu, Uenomachi Kaori, Katayama Yayoi, Koga Hiromi, Chikamoto Naoko, Kuwata Yuko, Torigoe Junko, Arimoto Masako, Tokumaru Toshiaki, Ikewaki Katsunori, Nohara Atsushi, Otsubo Yoshihiko, Yanagi Koji, Yoshida Masayuki, Harada-Shiba Mariko. ホモ接合型家族性高コレステロール血症の日本人患者におけるロミタピド治療に対する56週間の低脂肪食摂取(Dietary Intake during 56 Weeks of a Low-Fat Diet for Lomitapide Treatment in Japanese Patients with Homozygous Familial Hypercholesterolemia) Journal of Atherosclerosis and Thrombosis. 2019.01; 26 (1): 72-83. ( ichushi )

  54. Kameyama Noriko, Maruyama Chizuko, Kitagawa Fuyuha, Nishii Kazunobu, Uenomachi Kaori, Katayama Yayoi, Koga Hiromi, Chikamoto Naoko, Kuwata Yuko, Torigoe Junko, Arimoto Masako, Tokumaru Toshiaki, Ikewaki Katsunori, Nohara Atsushi, Otsubo Yoshihiko, Yanagi Koji, Yoshida Masayuki, Harada-Shiba Mariko. Dietary Intake during 56 Weeks of a Low-Fat Diet for Lomitapide Treatment in Japanese Patients with Homozygous Familial Hypercholesterolemia JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS. 2019; 26 (1): 72-83. ( PubMed, DOI )

  55. Nohara Atsushi, Otsubo Yoshihiko, Yanagi Koji, Yoshida Masayuki, Ikewaki Katsunori, Harada-Shiba Mariko, Jurecka Agnieszka. Safety and Efficacy of Lomitapide in Japanese Patients with Homozygous Familial Hypercholesterolemia (HoFH): Results from the AEGR-733-301 Long-Term Extension Study JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS. 2019; 26 (4): 368-377. ( PubMed, DOI )

  56. Kamijo Y, Ishii H, Yamamoto T, Kobayashi K, Asano H, Miake S, Kanda E, Urata H, Yoshida M. Potential Impact on Lipoprotein Subfractions in Type 2 Diabetes. Clinical medicine insights. Endocrinology and diabetes. 2019; 12 1179551419866811. ( PubMed, DOI )

  57. Kawashima Saki, Funakoshi Tomoko, Sato Yasunori, Saito Norikatsu, Ohsawa Hajime, Kurita Katsumi, Nagata Kisaburo, Yoshida Masayuki, Ishigami Akihito. Protective effect of pre- and post-vitamin C treatments on UVB-irradiation-induced skin damage SCIENTIFIC REPORTS. 2018.11; 8 (1): 16199. ( PubMed, DOI )

  58. Bloss Jeffrey D., Nohara Atsushi, Otsubo Yoshihiko, Yanagi Koji, Yoshida Masayuki, Ikewaki Katsunori, Harada-Shiba Mariko, Jurecka Agnieszka. ホモ接合性家族性高コレステロール血症(HoFH)の日本人患者におけるlomitapideの安全性と有効性(Safety and efficacy of lomitapide in Japanese patients with Homozygous Familial Hypercholesterolemia(HoFH)) 日本心臓病学会学術集会抄録. 2018.09; 66回 P-026. ( ichushi )

  59. Kitamura Kazutaka, Sato Kayoko, Sawabe Motoji, Yoshida Masayuki, Hagiwara Nobuhisa. P-Selectin Glycoprotein Ligand-1 (PSGL-1) Expressing CD4 T Cells Contribute Plaque Instability in Acute Coronary Syndrome CIRCULATION JOURNAL. 2018.08; 82 (8): 2128-+. ( PubMed, DOI )

  60. Kitamura Kazutaka, Sato Kayoko, Sawabe Motoji, Yoshida Masayuki, Hagiwara Nobuhisa. P-selectin glycoprotein ligand-1(PSGL-1)発現CD4 T細胞は急性冠動脈症候群におけるプラーク不安定性の一因となる(P-Selectin Glycoprotein Ligand-1(PSGL-1) Expressing CD4 T Cells Contribute Plaque Instability in Acute Coronary Syndrome) Circulation Journal. 2018.07; 82 (8): 2128-2135. ( ichushi )

  61. Tani Mariko, Kamata Yuko, Deushi Michiyo, Osaka Mizuko, Yoshida Masayuki. 7-Ketocholesterol enhances leukocyte adhesion to endothelial cells via p38MAPK pathway PLOS ONE. 2018.07; 13 (7): e0200499. ( PubMed, DOI )

  62. Yoshida Masayuki, Osaka Mizuko. POTENTIAL ROLE OF NEUTROPHIL-MEDIATED VASCULAR INFLAMMATION AND NET FORMATION IN ATHEROSCLEROSIS ATHEROSCLEROSIS SUPPLEMENTS. 2018.06; 32 107.

  63. Kamijo Yuka, Kanda Eiichiro, Horiuchi Hayato, Kounoue Noriyuki, Ono Keisuke, Maeda Keizo, Yanai Akane, Honda Kazuya, Tsujimoto Ryuji, Yanagi Mai, Ishibashi Yoshitaka, Yoshida Masayuki. 血液透析患者における動静脈瘻の血流音解析による血圧の連続モニタリング(Continuous monitoring of blood pressure by analyzing the blood flow sound of arteriovenous fistula in hemodialysis patients) Clinical and Experimental Nephrology. 2018.06; 22 (3): 677-683. ( ichushi )

  64. Asami Masahiko, Tanabe Kengo, Ito Shunsuke, Yoshida Eri, Aoki Jiro, Tanimoto Shuzou, Horiuchi Yu, Yoshida Masayuki. Impact of Indoxyl Sulfate on Coronary Plaques in Patients on Hemodialysis INTERNATIONAL HEART JOURNAL. 2018.05; 59 (3): 489-496. ( PubMed, DOI )

  65. Asami Masahiko, Tanabe Kengo, Ito Shunsuke, Yoshida Eri, Aoki Jiro, Tanimoto Shuzou, Horiuchi Yu, Yoshida Masayuki. 血液透析患者における冠動脈プラークに対するインドキシル硫酸の影響(Impact of Indoxyl Sulfate on Coronary Plaques in Patients on Hemodialysis) International Heart Journal. 2018.05; 59 (3): 489-496. ( ichushi )

  66. 鶴 裕美, 大坂 瑞子, 吉田 雅幸. 高脂肪食誘発性の血管の炎症における補体系D因子の潜在的役割(Potential Role of Complement Factor D in High-fat Diet-induced Vascular Inflammation) 日本循環器学会学術集会抄録集. 2018.03; 82回 PJ035-2. ( ichushi )

  67. Kamijo Yuka, Kanda Eiichiro, Ishibashi Yoshitaka, Yoshida Masayuki. SARCOPENIA AND FRAILTY IN PD: IMPACT ON MORTALITY, MALNUTRITION, AND INFLAMMATION PERITONEAL DIALYSIS INTERNATIONAL. 2018; 38 (6): 447-454. ( PubMed, DOI )

  68. Michiyo Deushi, Mizuko Osaka, Kaku Nakano, Kyoichi Osada, Kensuke Egashira, Masayuki Yoshida. Ezetimibe reduced hepatic steatosis induced by dietary oxysterols in nonhuman primates. FEBS Open Bio. 2016.10; 6 (10): 1008-1015. ( PubMed, DOI )

  69. Shunsuke Ito, Mizuko Osaka, Takeo Edamatsu, Yoshiharu Itoh, Masayuki Yoshida. Crucial Role of the Aryl Hydrocarbon Receptor (AhR) in Indoxyl Sulfate-Induced Vascular Inflammation. J. Atheroscler. Thromb.. 2016.08; 23 (8): 960-975. ( PubMed, DOI )

  70. Mizuko Osaka, Shunsuke Ito, Masaki Honda, Yukihiro Inomata, Kensuke Egashira, Masayuki Yoshida. Critical role of the C5a-activated neutrophils in high-fat diet-induced vascular inflammation. Sci Rep. 2016.02; 6 21391. ( PubMed, DOI )

  71. Eiichiro Kanda, Masumi Ai, Mitsuyo Okazaki, Masayuki Yoshida, Yoshitaka Maeda. Association of High-Density Lipoprotein Subclasses with Chronic Kidney Disease Progression, Atherosclerosis, and Klotho. PLoS ONE. 2016; 11 (11): e0166459. ( PubMed, DOI )

  72. Hiroshi Kataoka, Yuno Ariyama, Michiyo Deushi, Mizuko Osaka, Kosaku Nitta, Masayuki Yoshida. Inhibitory Effect of Serotonin Antagonist on Leukocyte-Endothelial Interactions In Vivo and In Vitro. PLoS ONE. 2016; 11 (1): e0147929. ( PubMed, DOI )

  73. Matsue Y, Yoshida K, Hoshino M, Yonetsu T, Suzuki M, Matsumura A, Hashimoto Y, Yoshida M.. Clinical features and prognosis of type 2 myocardial infarction in vasospastic angina. Am J Med. 2015; 128 389-395.

  74. Hsu P, Ai M, Kanda E, Yu NC, Chen HL, Chen HW, Cheng MH, Kohzuma T, Schaefer EJ, Yoshida M. A comparison of glycated albumin and glycosylated hemoglobin for the screening of diabetes mellitus in Taiwan Atherosclerosis. 2015; 242 327-333.

  75. Nishina K, Piao W, Yoshida-Tanaka K, Sujino Y, Nishina T, Yamamoto T, Nitta K, Yoshioka K, Kuwahara H, Yasuhara H, Baba T, Ono F, Miyata K, Miyake K, Seth PP, Low A, Yoshida M, Bennett CF, Kataoka K, Mizusawa H, Obika S, Yokota T. DNA/RNA heteroduplex oligonucleotide for highly efficient gene silencing Nat Commun. 2015; 6 7969.

  76. Murakami M, Nishina K, Watanabe C, Yoshida-Tanaka K, Piao W, Kuwahara H, Horikiri Y, Miyata K, Nishiyama N, Kataoka K, Yoshida M, Mizusawa H, Yokota T. Enteral siRNA delivery technique for therapeutic gene silencing in the liver via the lymphatic route Sci Rep. 2015; 5 17035.

  77. Kotaro Aihara, Mizuko Osaka, Masayuki Yoshida. Oral administration of the milk casein-derived tripeptide Val-Pro-Pro attenuates high-fat diet-induced adipose tissue inflammation in mice. Br. J. Nutr.. 2014.08; 112 (4): 513-519. ( PubMed, DOI )

  78. Hiroyuki Daida, Ryuji Nohara, Mitsumasa Hata, Kohei Kaku, Ryuzo Kawamori, Junji Kishimoto, Masahiko Kurabayashi, Izuru Masuda, Ichiro Sakuma, Tsutomu Yamazaki, Hiroyoshi Yokoi, Masayuki Yoshida. Can Intensive Lipid-Lowering Therapy Improve the Carotid Intima-Media Thickness in Japanese Subjects Under Primary Prevention for Cardiovascular Disease?: The JART and JART Extension Subanalysis. J. Atheroscler. Thromb.. 2014.07; 21 (7): 739-754. ( PubMed )

  79. Shunsuke Ito, Masayuki Yoshida. Protein-bound uremic toxins: new culprits of cardiovascular events in chronic kidney disease patients. Toxins (Basel). 2014.02; 6 (2): 665-678. ( PubMed, DOI )

  80. Yuya Matsue, Kazuki Yoshida, Wataru Nagahori, Masakazu Ohno, Makoto Suzuki, Akihiko Matsumura, Yuji Hashimoto, Masayuki Yoshida. Peripheral microvascular dysfunction predicts residual risk in coronary artery disease patients on statin therapy. Atherosclerosis. 2014.01; 232 (1): 186-190. ( PubMed, DOI )

  81. Katsuhiko Hamada, Mizuko Osaka, Masayuki Yoshida. Cell density impacts epigenetic regulation of cytokine-induced E-selectin gene expression in vascular endothelium. PLoS ONE. 2014; 9 (4): e90502. ( PubMed, DOI )

  82. Eiichiro Kanda, Masumi Ai, Renjiro Kuriyama, Masayuki Yoshida, Tatsuo Shiigai. Dietary acid intake and kidney disease progression in the elderly. Am. J. Nephrol.. 2014; 39 (2): 145-152. ( PubMed, DOI )

  83. Hiroyoshi Yokoi, Ryuji Nohara, Hiroyuki Daida, Mitsumasa Hata, Kohei Kaku, Ryuzo Kawamori, Junji Kishimoto, Masahiko Kurabayashi, Izuru Masuda, Ichiro Sakuma, Tsutomu Yamazaki, Masayuki Yoshida. Change in carotid intima-media thickness in a high-risk group of patients by intensive lipid-lowering therapy with rosuvastatin: subanalysis of the JART study. Int Heart J. 2014; 55 (2): 146-152. ( PubMed )

  84. Ito S, Higuchi Y, Yagi Y, Nishijima F, Yamato H, Ishii H, Osaka M, Yoshida M. Reduction of indoxyl sulfate by AST-120 attenuates monocyte inflammation related to chronic kidney disease. J Leukoc Biol. 2013.06; 93 (6): 837-845. ( PubMed, DOI )

  85. Eiichiro Kanda, Masumi Ai, Asami Iwamoto, Mitsuyo Okazaki, Yoshitaka Maeda, Sei Sasaki, Masayuki Yoshida. Relationship between Icodextrin use and decreased level of small low-density lipoprotein cholesterol fractioned by high-performance gel permeation chromatography. BMC Nephrol. 2013; 14 234. ( PubMed, DOI )

  86. Yamazaki Tsutomu, Nohara Ryuji, Daida Hiroyuki, Hata Mitsumasa, Kaku Kohei, Kawamori Ryuzo, Kishimoto Junji, Kurabayashi Masahiko, Masuda Izuru, Sakuma Ichiro, Yokoi Hiroyoshi, Yoshida Masayuki. Intensive Lipid-Lowering Therapy for Slowing Progression as Well as Inducing Regression of Atherosclerosis in Japanese Patients: Subanalysis of the JART Study International Heart Journal. 2013; 54 (1): 33-39. ( ichushi )

  87. Osaka M, Hagita S, Yoshida M. In vivo imaging of leukocyte recruitment to the atheroprone femoral artery reveals anti-inflammatory effects of rosuvastatin. Biomed Res Int. 2013; 2013 962369. ( PubMed, DOI )

  88. Ryuji Nohara, Hiroyuki Daida, Mitsumasa Hata, Kohei Kaku, Ryuzo Kawamori, Junji Kishimoto, Masahiko Kurabayashi, Izuru Masuda, Ichiro Sakuma, Tsutomu Yamazaki, Hiroyoshi Yokoi, Masayuki Yoshida, . Effect of long-term intensive lipid-lowering therapy with rosuvastatin on progression of carotid intima-media thickness--Justification for Atherosclerosis Regression Treatment (JART) extension study. Circ. J.. 2013; 77 (6): 1526-1533. ( PubMed )

  89. Eiichiro Kanda, Masumi Ai, Mitsuyo Okazaki, Yoshitaka Maeda, Sei Sasaki, Masayuki Yoshida. The association of very-low-density lipoprotein with ankle-brachial index in peritoneal dialysis patients with controlled serum low-density lipoprotein cholesterol level. BMC Nephrol. 2013; 14 212. ( PubMed, DOI )

  90. Eiichiro Kanda, Masumi Ai, Masayuki Yoshida, Renjiro Kuriyama, Tatsuo Shiigai. High serum bicarbonate level within the normal range prevents the progression of chronic kidney disease in elderly chronic kidney disease patients. BMC Nephrol. 2013; 14 4. ( PubMed, DOI )

  91. Matsue Y, Suzuki M, Nagahori W, Ohno M, Matsumura A, Hashimoto Y, Yoshida K, Yoshida M. Endothelial dysfunction measured by peripheral arterial tonometry predicts prognosis in patients with heart failure with preserved ejection fraction. Int J Cardiol. 2012.09; ( PubMed, DOI )

  92. Ishii H, Yoshida M. [Blood lipid measurement]. Nihon Rinsho. 2012.05; 70 Suppl 3 455-458. ( PubMed )

  93. Gomita Keiko, Sato Kayoko, Yoshida Masayuki, Hagiwara Nobuhisa. PSGL-1-Expressing CD4 T Cells Induce Endothelial Cell Apoptosis in Perimenopausal Women Journal of Atherosclerosis and Thrombosis. 2012; 19 (3): 227-236. ( ichushi )

  94. Gomita K, Sato K, Yoshida M, Hagiwara N. PSGL-1-expressing CD4 T cells induce endothelial cell apoptosis in perimenopausal women. J Atheroscler Thromb. 2012; 19 (3): 227-236. ( PubMed )

  95. Ryuji Nohara, Hiroyuki Daida, Mitsumasa Hata, Kohei Kaku, Ryuzo Kawamori, Junji Kishimoto, Masahiko Kurabayashi, Izuru Masuda, Ichiro Sakuma, Tsutomu Yamazaki, Hiroyoshi Yokoi, Masayuki Yoshida, . Effect of intensive lipid-lowering therapy with rosuvastatin on progression of carotid intima-media thickness in Japanese patients: Justification for Atherosclerosis Regression Treatment (JART) study. Circ. J.. 2012; 76 (1): 221-229. ( PubMed )

  96. Eiichiro Kanda, Masayuki Yoshida, Sei Sasaki. Applicability of fibroblast growth factor 23 for evaluation of risk of vertebral fracture and chronic kidney disease-mineral bone disease in elderly chronic kidney disease patients. BMC Nephrol. 2012; 13 122. ( PubMed, DOI )

  97. Kuwahara H, Nishina K, Yoshida K, Nishina T, Yamamoto M, Saito Y, Piao W, Yoshida M, Mizusawa H, Yokota T. Efficient in vivo delivery of siRNA into brain capillary endothelial cells along with endogenous lipoprotein. Mol Ther. 2011.12; 19 (12): 2213-2221. ( PubMed, DOI )

  98. Hagita S, Osaka M, Shimokado K, Yoshida M. Combination of amlodipine and atorvastatin synergistically reduces leukocyte recruitment to mechanically injured mouse femoral artery. Hypertens Res. 2011.04; 34 (4): 450-455. ( PubMed, DOI )

  99. Ishii H, Yoshida M. [Platelets, coagulation, and fibrinolysis in atherosclerosis formation]. Nihon Rinsho. 2011.01; 69 (1): 50-54. ( PubMed )

  100. Yoshida M. [High sensitive CRP: hsCRP]. Nihon Rinsho. 2011.01; 69 Suppl 1 503-506. ( PubMed )

  101. Yoshida M. Novel role of NPC1L1 in the regulation of hepatic metabolism: potential contribution of ezetimibe in NAFLD/NASH treatment. Curr Vasc Pharmacol. 2011.01; 9 (1): 121-123. ( PubMed )

  102. Tani Mariko, Kawakami Akio, Mizuno Yuki, Imase Reina, Ito Yasuki, Kondo Kazuo, Ishii Hideto, Yoshida Masayuki. Small Dense LDL Enhances THP-1 Macrophage Foam Cell Formation Journal of Atherosclerosis and Thrombosis. 2011; 18 (8): 698-704. ( ichushi )

  103. Tani M, Kawakami A, Mizuno Y, Imase R, Ito Y, Kondo K, Ishii H, Yoshida M. Small dense LDL enhances THP-1 macrophage foam cell formation. J Atheroscler Thromb. 2011; 18 (8): 698-704. ( PubMed )

  104. Hagita S, Osaka M, Shimokado K, Yoshida M. Adipose inflammation initiates recruitment of leukocytes to mouse femoral artery: role of adipo-vascular axis in chronic inflammation. PLoS One. 2011; 6 (5): e19871. ( PubMed, DOI )

  105. Ito S, Osaka M, Higuchi Y, Nishijima F, Ishii H, Yoshida M. Indoxyl sulfate induces leukocyte-endothelial interactions through up-regulation of E-selectin. J Biol Chem. 2010.12; 285 (50): 38869-38875. ( PubMed, DOI )

  106. Abe Y, Kawakami A, Osaka M, Uematsu S, Akira S, Shimokado K, Sacks FM, Yoshida M. Apolipoprotein CIII induces monocyte chemoattractant protein-1 and interleukin 6 expression via Toll-like receptor 2 pathway in mouse adipocytes. Arterioscler Thromb Vasc Biol. 2010.11; 30 (11): 2242-2248. ( PubMed, DOI )

  107. Ai M, Yoshida M. [Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study]. Nihon Rinsho. 2010.11; 68 Suppl 9 285-290. ( PubMed )

  108. Yoshida M. Not sleeping well can damage your heart. Hypertens Res. 2010.06; 33 (6): 535-536. ( PubMed, DOI )

  109. Ishii H, Yoshida M. [Inflammatory cytokines]. Nihon Rinsho. 2010.05; 68 (5): 819-822. ( PubMed )

  110. Kojima C, Ino J, Ishii H, Nitta K, Yoshida M. MMP-9 inhibition by ACE inhibitor reduces oxidized LDL-mediated foam-cell formation. J Atheroscler Thromb. 2010.02; 17 (1): 97-105. ( PubMed )

  111. Nomura M, Ishii H, Kawakami A, Yoshida M. Inhibition of hepatic Niemann-Pick C1-like 1 improves hepatic insulin resistance. Am J Physiol Endocrinol Metab. 2009.11; 297 (5): E1030-8. ( PubMed, DOI )

  112. Ino J, Kojima C, Osaka M, Nitta K, Yoshida M. Dynamic observation of mechanically-injured mouse femoral artery reveals an antiinflammatory effect of renin inhibitor. Arterioscler Thromb Vasc Biol. 2009.11; 29 (11): 1858-1863. ( PubMed, DOI )

  113. Sermsathanasawadi N, Ishii H, Igarashi K, Miura M, Yoshida M, Inoue Y, Iwai T. Enhanced adhesion of early endothelial progenitor cells to radiation-induced senescence-like vascular endothelial cells in vitro. J Radiat Res. 2009.09; 50 (5): 469-475. ( PubMed )

  114. Yamada H, Yoshida M, Nakano Y, Suganami T, Satoh N, Mita T, Azuma K, Itoh M, Yamamoto Y, Kamei Y, Horie M, Watada H, Ogawa Y. In vivo and in vitro inhibition of monocyte adhesion to endothelial cells and endothelial adhesion molecules by eicosapentaenoic acid. Arterioscler Thromb Vasc Biol. 2008.12; 28 (12): 2173-2179. ( PubMed, DOI )

  115. Haraguchi G, Kosuge H, Maejima Y, Suzuki J, Imai T, Yoshida M, Isobe M. Pioglitazone reduces systematic inflammation and improves mortality in apolipoprotein E knockout mice with sepsis. Intensive Care Med. 2008.07; 34 (7): 1304-1312. ( PubMed, DOI )

  116. Tsujimura Y, Obata K, Mukai K, Shindou H, Yoshida M, Nishikado H, Kawano Y, Minegishi Y, Shimizu T, Karasuyama H. Basophils play a pivotal role in immunoglobulin-G-mediated but not immunoglobulin-E-mediated systemic anaphylaxis. Immunity. 2008.04; 28 (4): 581-589. ( PubMed, DOI )

  117. Hagita S, Osaka M, Shimokado K, Yoshida M. Oxidative stress in mononuclear cells plays a dominant role in their adhesion to mouse femoral artery after injury. Hypertension. 2008.03; 51 (3): 797-802. ( PubMed, DOI )

  118. Nakamura N, Yoshida M, Umeda M, Huang Y, Kitajima S, Inoue Y, Ishikawa I, Iwai T. Extended exposure of lipopolysaccharide fraction from Porphyromonas gingivalis facilitates mononuclear cell adhesion to vascular endothelium via Toll-like receptor-2 dependent mechanism. Atherosclerosis. 2008.01; 196 (1): 59-67. ( PubMed, DOI )

  119. Ishii H, Tsukada T, Yoshida M. Angiotensin II type-I receptor blocker, candesartan, improves brachial-ankle pulse wave velocity independent of its blood pressure lowering effects in type 2 diabetes patients. Intern Med. 2008; 47 (23): 2013-2018. ( PubMed )

  120. Kojima C, Kawakami A, Takei T, Nitta K, Yoshida M. Angiotensin-converting enzyme inhibitor attenuates monocyte adhesion to vascular endothelium through modulation of intracellular zinc. J Pharmacol Exp Ther. 2007.12; 323 (3): 855-860. ( PubMed, DOI )

  121. Deushi M, Nomura M, Kawakami A, Haraguchi M, Ito M, Okazaki M, Ishii H, Yoshida M. Ezetimibe improves liver steatosis and insulin resistance in obese rat model of metabolic syndrome. FEBS Lett. 2007.12; 581 (29): 5664-5670. ( PubMed, DOI )

  122. Mori D, Ishii H, Kojima C, Nitta N, Nakajima K, Yoshida M. Cilostazol inhibits monocytic cell adhesion to vascular endothelium via upregulation of cAMP. J Atheroscler Thromb. 2007.10; 14 (5): 213-218. ( PubMed )

  123. Tani M, Kawakami A, Nagai M, Shimokado K, Kondo K, Yoshida M. Sphingosine 1-phosphate (S1P) inhibits monocyte-endothelial cell interaction by regulating of RhoA activity. FEBS Lett. 2007.10; 581 (24): 4621-4626. ( PubMed, DOI )

  124. Tanaka Y, Ishii H, Hiraoka M, Miyasaka N, Kuroiwa T, Hajjar KA, Nagaoka T, Duong TQ, Ohno K, Yoshida M. Efficacy of recombinant annexin 2 for fibrinolytic therapy in a rat embolic stroke model: a magnetic resonance imaging study. Brain Res. 2007.08; 1165 135-143. ( PubMed, DOI )

  125. Takano Y, Shimokado K, Hata Y, Yoshida M. HIV envelope protein gp120-triggered CD4+ T-cell adhesion to vascular endothelium is regulated via CD4 and CXCR4 receptors. Biochim Biophys Acta. 2007.05; 1772 (5): 549-555. ( PubMed, DOI )

  126. Osaka M, Hagita S, Haraguchi M, Kajimura M, Suematsu M, Yoshida M. Real-time imaging of mechanically injured femoral artery in mice reveals a biphasic pattern of leukocyte accumulation. Am J Physiol Heart Circ Physiol. 2007.04; 292 (4): H1876-82. ( PubMed, DOI )

  127. Nishiwaki Y, Yoshida M, Iwaguro H, Masuda H, Nitta N, Asahara T, Isobe M. Endothelial E-selectin potentiates neovascularization via endothelial progenitor cell-dependent and -independent mechanisms. Arterioscler Thromb Vasc Biol. 2007.03; 27 (3): 512-518. ( PubMed, DOI )

  128. Ishii H, Hiraoka M, Tanaka A, Shimokado K, Yoshida M. Recombinant annexin-2 inhibits the progress of diabetic nephropathy in a diabetic mouse model via recovery of hypercoagulability. Thromb Haemost. 2007.01; 97 (1): 124-128. ( PubMed )

  129. Takahashi K, Shimokado K, Yoshida M. SDF-1-induced adhesion of monocytes to vascular endothelium is modulated by azelnidipine via protein kinase C inhibition. Eur J Pharmacol. 2006.12; 552 (1-3): 162-169. ( PubMed, DOI )

  130. Takei T, Hiraoka M, Nitta K, Uchida K, Deushi M, Yu T, Nitta N, Tsuchiya K, Yumura W, Nihei H, Nakamura Y, Yoshida M. Functional impact of IgA nephropathy-associated selectin gene haplotype on leukocyte-endothelial interaction. Immunogenetics. 2006.06; 58 (5-6): 355-361. ( PubMed, DOI )

  131. Kasuya N, Kishi Y, Isobe M, Yoshida M, Numano F. P-selectin expression, but not GPIIb/IIIa activation, is enhanced in the inflammatory stage of Takayasu's arteritis. Circ J. 2006.05; 70 (5): 600-604. ( PubMed )

  132. Imada T, Tatsumi T, Mori Y, Nishiue T, Yoshida M, Masaki H, Okigaki M, Kojima H, Nozawa Y, Nishiwaki Y, Nitta N, Iwasaka T, Matsubara H. Targeted delivery of bone marrow mononuclear cells by ultrasound destruction of microbubbles induces both angiogenesis and arteriogenesis response. Arterioscler Thromb Vasc Biol. 2005.10; 25 (10): 2128-2134. ( PubMed, DOI )

  133. Gotoh R, Suzuki J, Kosuge H, Kakuta T, Sakamoto S, Yoshida M, Isobe M. E-selectin blockade decreases adventitial inflammation and attenuates intimal hyperplasia in rat carotid arteries after balloon injury. Arterioscler Thromb Vasc Biol. 2004.11; 24 (11): 2063-2068. ( PubMed, DOI )

  134. Hiraoka M, Nitta N, Nagai M, Shimokado K, Yoshida M. MCP-1-induced enhancement of THP-1 adhesion to vascular endothelium was modulated by HMG-CoA reductase inhibitor through RhoA GTPase-, but not ERK1/2-dependent pathway. Life Sci. 2004.07; 75 (11): 1333-1341. ( PubMed, DOI )

  135. Onai Y, Suzuki J, Nishiwaki Y, Gotoh R, Berens K, Dixon R, Yoshida M, Ito H, Isobe M. Blockade of cell adhesion by a small molecule selectin antagonist attenuates myocardial ischemia/reperfusion injury. Eur J Pharmacol. 2003.11; 481 (2-3): 217-225. ( PubMed )

  136. Fujiyama S, Amano K, Uehira K, Yoshida M, Nishiwaki Y, Nozawa Y, Jin D, Takai S, Miyazaki M, Egashira K, Imada T, Iwasaka T, Matsubara H. Bone marrow monocyte lineage cells adhere on injured endothelium in a monocyte chemoattractant protein-1-dependent manner and accelerate reendothelialization as endothelial progenitor cells. Circ Res. 2003.11; 93 (10): 980-989. ( PubMed, DOI )

  137. Toriumi Y, Hiraoka M, Watanabe M, Yoshida M. Pioglitazone reduces monocyte adhesion to vascular endothelium under flow by modulating RhoA GTPase and focal adhesion kinase. FEBS Lett. 2003.10; 553 (3): 419-422. ( PubMed )

  138. Nishiwaki Y, Yokota T, Hiraoka M, Miyagishi M, Taira K, Isobe M, Mizusawa H, Yoshida M. Introduction of short interfering RNA to silence endogenous E-selectin in vascular endothelium leads to successful inhibition of leukocyte adhesion. Biochem Biophys Res Commun. 2003.10; 310 (4): 1062-1066. ( PubMed )

  139. Yu T, Morita I, Shimokado K, Iwai T, Yoshida M. Amlodipine modulates THP-1 cell adhesion to vascular endothelium via inhibition of protein kinase C signal transduction. Hypertension. 2003.09; 42 (3): 329-334. ( PubMed, DOI )

  140. Yoshida M, Takano Y, Sasaoka T, Izumi T, Kimura A. E-selectin polymorphism associated with myocardial infarction causes enhanced leukocyte-endothelial interactions under flow conditions. Arterioscler Thromb Vasc Biol. 2003.05; 23 (5): 783-788. ( PubMed, DOI )

  141. Yoshida M. Potential role of statins in inflammation and atherosclerosis. J Atheroscler Thromb. 2003; 10 (3): 140-144. ( PubMed )

  142. Kawakami A, Tanaka A, Nakajima K, Shimokado K, Yoshida M. Atorvastatin attenuates remnant lipoprotein-induced monocyte adhesion to vascular endothelium under flow conditions. Circ Res. 2002.08; 91 (3): 263-271. ( PubMed )

  143. Yoshida M, Sawada T, Ishii H, Gerszten RE, Rosenzweig A, Gimbrone MA Jr, Yasukochi Y, Numano F. Hmg-CoA reductase inhibitor modulates monocyte-endothelial cell interaction under physiological flow conditions in vitro: involvement of Rho GTPase-dependent mechanism. Arterioscler Thromb Vasc Biol. 2001.07; 21 (7): 1165-1171. ( PubMed )

  144. Fukuda Y, Kurihara N, Imoto I, Yasui K, Yoshida M, Yanagihara K, Park JG, Nakamura Y, Inazawa J. CD44 is a potential target of amplification within the 11p13 amplicon detected in gastric cancer cell lines. Genes Chromosomes Cancer. 2000.12; 29 (4): 315-324. ( PubMed )

  145. Ishii H, Yoshida M, Rosenzweig A, Gimbrone MA Jr, Yasukochi Y, Numano F. Adenoviral transduction of human E-selectin into isolated, perfused, rat aortic segments: an ex vivo model for studying leukocyte-endothelial interactions. J Leukoc Biol. 2000.11; 68 (5): 687-692. ( PubMed )

  146. Luscinskas FW, Gerszten RE, Garcia-Zepeda EA, Lim YC, Yoshida M, Ding HA, Gimbrone MA Jr, Luster AD, Rosenzweig A. C-C and C-X-C chemokines trigger firm adhesion of monocytes to vascular endothelium under flow conditions. Ann N Y Acad Sci. 2000.05; 902 288-293. ( PubMed )

  147. Gerszten RE, Garcia-Zepeda EA, Lim YC, Yoshida M, Ding HA, Gimbrone MA Jr, Luster AD, Luscinskas FW, Rosenzweig A. MCP-1 and IL-8 trigger firm adhesion of monocytes to vascular endothelium under flow conditions. Nature. 1999.04; 398 (6729): 718-723. ( PubMed, DOI )

  148. Yoshida M, Szente BE, Kiely JM, Rosenzweig A, Gimbrone MA Jr. Phosphorylation of the cytoplasmic domain of E-selectin is regulated during leukocyte-endothelial adhesion. J Immunol. 1998.07; 161 (2): 933-941. ( PubMed )

  149. Yoshida M, Gimbrone MA Jr. Novel roles for E-selectin in endothelial-leukocyte adhesion. Ann N Y Acad Sci. 1997.04; 811 493-497. ( PubMed )

  150. Yoshida M, Westlin WF, Wang N, Ingber DE, Rosenzweig A, Resnick N, Gimbrone MA Jr. Leukocyte adhesion to vascular endothelium induces E-selectin linkage to the actin cytoskeleton. J Cell Biol. 1996.04; 133 (2): 445-455. ( PubMed )

  151. Yoshida M, Kimura A, Katsuragi K, Numano F, Sasazuki T. DNA typing of HLA-B gene in Takayasu's arteritis. Tissue Antigens. 1993.08; 42 (2): 87-90. ( PubMed )

  152. Yoshida M, Kimura A, Numano F, Sasazuki T. Polymerase-chain-reaction-based analysis of polymorphism in the HLA-B gene. Hum Immunol. 1992.08; 34 (4): 257-266. ( PubMed )

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Conference Activities & Talks 【 display / non-display

  1. Yoshida Masayuki. Neutrophil Citrullination Plays a Pivotal Role during Vascular Inflammation(タイトル和訳中). 日本循環器学会学術集会抄録集 2023.03.01

  2. Yoshida Masayuki. Shared Decision-Making Approach in Cardiovascular Genetics(タイトル和訳中). 日本循環器学会学術集会抄録集 2023.03.01

  3. Kanae Iwata, Masayuki Yoshida. Researchers’ perception of electronic informed consent under the new Ethical Guidelines for Medical. PRIM&R Annual Conference 2022.12 web

  4. 大坂 瑞子, 吉田 雅幸. ペマフィブラートは高脂肪食を摂取したLDL受容体欠損(LDLR-/-)マウスにおいてヒストンH3のシトルリン化阻害を介して好中球接着を抑制する(Pemafibrate Attenuates High-Fat Diet-Induced Neutrophil Adhesion via Inhibition of HistoneH3 Citrullination in LDLR-/- Mice). 日本循環器学会学術集会抄録集 2022.03.01

  5. Tsuru Hiromi, Osaka Mizuko, Yoshida Masayuki. 補体D因子は長期高脂肪食条件下で脂肪肝の発生を促進する(Complement Factor D Facilitates the Development of Fatty Liver under Long-term but not Short-term High-fat Diet-feeding Conditions). 日本循環器学会学術集会抄録集 2021.03.01

  6. Dewan Syed Masudur Rahman, Osaka Mizuko, Deushi Michiyo, Yoshida Masayuki. C5a刺激により好中球様細胞に分化したHL-60がMCP-1分泌を介して単球性THP-1の遊走を誘発する(C5a-stimulated Neutrophil-like Differentiated HL-60 Induced Migration of Monocytic THP-1 through the Secretion of MCP-1). 日本循環器学会学術集会抄録集 2021.03.01

  7. Dewan Syed Masudur Rahman, Osaka Mizuko, Deushi Michiyo, Yoshida Masayuki. C5a刺激により好中球様細胞に分化したHL-60がMCP-1分泌を介して単球性THP-1の遊走を誘発する(C5a-stimulated Neutrophil-like Differentiated HL-60 Induced Migration of Monocytic THP-1 through the Secretion of MCP-1). 日本循環器学会学術集会抄録集 2021.03.01

  8. Osaka Mizuko, Ito Shunsuke, Yoshida Masayuki. High-Fat Diet-triggered Neutrophil Activation Initiates Leukocyte Adhesion to Murine Femoral Artery in vivo. Japanese Circulation Society Scientific Meeting 2016.03

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Others 【 display / non-display

  • Using Mice to Open the Way to Prevent Blocked Arteries,2021.07