Matsubayashi T, Yoshioka K, Lei Mon SS, Katsuyama M, Jia C, Yamaguchi T, Hara RI, Nagata T, Nakagawa O, Obika S, Yokota T. Favorable efficacy and reduced acute neurotoxicity by antisense oligonucleotides with 2',4'-BNA/LNA with 9-(aminoethoxy)phenoxazine. Molecular therapy. Nucleic acids. 2024.06; 35 (2): 102161. ( PubMed, DOI )

Sano T, Nagata T, Ebihara S, Yoshida-Tanaka K, Nakamura A, Sasaki A, Shimozawa A, Mochizuki H, Uchihara T, Hasegawa M, Yokota T. Effects of local reduction of endogenous α-synuclein using antisense oligonucleotides on the fibril-induced propagation of pathology through the neural network in wild-type mice. Acta neuropathologica communications. 2024.05; 12 (1): 75. ( PubMed, DOI )

Ono D, Kawai H, Kuwahara H, Yokota T. Automated whole slide morphometry of sural nerve biopsy using machine learning. Neuropathology and applied neurobiology. 2024.04; 50 (2): e12967. ( PubMed, DOI )

Amano E, Sato W, Kimura Y, Kimura A, Lin Y, Okamoto T, Sato N, Yokota T, Yamamura T. CD11c(high) B Cell Expansion Is Associated With Severity and Brain Atrophy in Neuromyelitis Optica. Neurology(R) neuroimmunology & neuroinflammation. 2024.03; 11 (2): e200206. ( PubMed, DOI )

Sanjo N, Suzuki M, Yoshihama R, Toyoshima Y, Mizuta I, Fujita N, Usuda H, Uchiyama Y, Yasuda R, Yoshida T, Yamada M, Yokota T. Substitution of Glu to Lys at Codon 332 on the GFAP Gene Alone Is Causative for Adult-onset Alexander Disease. Internal medicine (Tokyo, Japan). 2024.01; 63 (2): 309-313. ( PubMed, DOI )

Okamoto T, Ishizuka T, Shimizu R, Asahina Y, Nakamura H, Shimizu Y, Nishida Y, Yokota T, Lin Y, Sato W, Yamamura T. Efficacy and Safety of the Natural Killer T Cell-Stimulatory Glycolipid OCH-NCNP1 for Patients With Relapsing Multiple Sclerosis: Protocol for a Randomized Placebo-Controlled Clinical Trial. JMIR research protocols. 2024.01; 13 e46709. ( PubMed, DOI )

Nishina K, Yoshioka K, Yokota T, Hara RI. Comparison of interaction between antimiR and microRNA versus HDO-antimiR and microRNA by molecular dynamics simulation. Nucleosides, nucleotides & nucleic acids. 2024.01; 1-16. ( PubMed, DOI )

Yum J, Aulia F, Kamiya K, Hori M, Qiao N, Kim BS, Naito M, Ogura S, Nagata T, Yokota T, Uchida S, Obika S, Kim HJ, Miyata K. Hydrophobicity Tuning of Cationic Polyaspartamide Derivatives for Enhanced Antisense Oligonucleotide Delivery. Bioconjugate chemistry. 2024.01; 35 (2): 125-131. ( PubMed, DOI )

Sanjo Nobuo, Suzuki Motohiro, Yoshihama Rei, Toyoshima Yasuko, Mizuta Ikuko, Fujita Nobuya, Usuda Hiroyuki, Uchiyama Yumiko, Yasuda Rei, Yoshida Tomokatsu, Yamada Masahito, Yokota Takanori. GFAP遺伝子コドン332におけるGluのLysへの置換は単独で成人発症アレキサンダー病の原因となる(Substitution of Glu to Lys at Codon 332 on the GFAP Gene Alone Is Causative for Adult-onset Alexander Disease) Internal Medicine. 2024.01; 63 (2): 309-313. ( ichushi )

Rayle Mamuti, Sato Nozomu, Ozaki Kokoro, Higashi Miwa, Okita Michi, Yajima Reiko, Amano Akiko, Mizusawa Hidehiro, Yokota Takanori, Ishikawa Kinya. Analysis of the polymorphic SCA37 locus in a cohort of 167 Japanese patients with degenerative ataxia(タイトル和訳中) Journal of Medical and Dental Sciences. 2024; 71 11-17. ( ichushi )

Maruoka H, Hattori T, Hase T, Takahashi K, Ohara M, Orimo S, Yokota T. Aberrant morphometric networks in Alzheimer's disease have hemispheric asymmetry and age dependence. The European journal of neuroscience. 2023.12; ( PubMed, DOI )

Kawai H, Matsubayashi T, Yokota T, Sanjo N. Serial changes in regional cerebral blood flow in Gerstmann-Sträussler-Scheinker disease caused by a Pro-to-Leu mutation at codon 105 in the prion protein gene. Prion. 2023.12; 17 (1): 138-140. ( PubMed, DOI )

Nakamura R, Tohnai G, Nakatochi M, Atsuta N, Watanabe H, Ito D, Katsuno M, Hirakawa A, Izumi Y, Morita M, Hirayama T, Kano O, Kanai K, Hattori N, Taniguchi A, Suzuki N, Aoki M, Iwata I, Yabe I, Shibuya K, Kuwabara S, Oda M, Hashimoto R, Aiba I, Ishihara T, Onodera O, Yamashita T, Abe K, Mizoguchi K, Shimizu T, Ikeda Y, Yokota T, Hasegawa K, Tanaka F, Nakashima K, Kaji R, Niwa JI, Doyu M, Terao C, Ikegawa S, Fujimori K, Nakamura S, Ozawa F, Morimoto S, Onodera K, Ito T, Okada Y, Okano H, Sobue G, Japanese Consortium for Amyotrophic Lateral Sclerosis research (JaCALS) study group. Genetic factors affecting survival in Japanese patients with sporadic amyotrophic lateral sclerosis: a genome-wide association study and verification in iPSC-derived motor neurons from patients. Journal of neurology, neurosurgery, and psychiatry. 2023.10; 94 (10): 816-824. ( PubMed, DOI )

Hirata K, Matsuoka K, Tagai K, Endo H, Tatebe H, Ono M, Kokubo N, Oyama A, Shinotoh H, Takahata K, Obata T, Dehghani M, Near J, Kawamura K, Zhang MR, Shimada H, Yokota T, Tokuda T, Higuchi M, Takado Y. Altered Brain Energy Metabolism Related to Astrocytes in Alzheimer's Disease. Annals of neurology. 2023.09; ( PubMed, DOI )

Hattori T, Ohara M, Yuasa T, Azuma R, Chen Q, Hanazawa R, Hirakawa A, Orimo S, Yokota T. Correlation of callosal angle at the splenium with gait and cognition in normal pressure hydrocephalus. Journal of neurosurgery. 2023.08; 139 (2): 481-491. ( PubMed, DOI )

Iida S, Kanouchi T, Hattori T, Kanai K, Nakazato T, Hattori N, Yokota T. Verification of propagation hypothesis in patients with sporadic hand onset amyotrophic lateral sclerosis. Acta neurologica Belgica. 2023.08; 123 (4): 1511-1517. ( PubMed, DOI )

Noda K, Hattori Y, Hori M, Nakaoku Y, Tanaka A, Yoshimoto T, Nishimura K, Yokota T, Harada-Shiba M, Ihara M. Amplified Risk of Intracranial Artery Stenosis/Occlusion Associated With RNF213 p.R4810K in Familial Hypercholesterolemia. JACC. Asia. 2023.08; 3 (4): 625-633. ( PubMed, DOI )

Miura M, Sakaue F, Matsuno H, Morita K, Yoshida A, Hara RI, Nishimura R, Nishida Y, Yokogawa M, Osawa M, Yokota T. TDP-43 N-terminal domain dimerisation or spatial separation by RNA binding decreases its propensity to aggregate. FEBS letters. 2023.06; 597 (12): 1667-1676. ( PubMed, DOI )

Mitsui J, Matsukawa T, Uemura Y, Kawahara T, Chikada A, Porto KJL, Naruse H, Tanaka M, Ishiura H, Toda T, Kuzuyama H, Hirano M, Wada I, Ga T, Moritoyo T, Takahashi Y, Mizusawa H, Ishikawa K, Yokota T, Kuwabara S, Sawamoto N, Takahashi R, Abe K, Ishihara T, Onodera O, Matsuse D, Yamasaki R, Kira JI, Katsuno M, Hanajima R, Ogata K, Takashima H, Matsushima M, Yabe I, Sasaki H, Tsuji S. High-dose ubiquinol supplementation in multiple-system atrophy: a multicentre, randomised, double-blinded, placebo-controlled phase 2 trial. EClinicalMedicine. 2023.05; 59 101920. ( PubMed, DOI )

Honda T, Matsumura K, Hashimoto Y, Yokota T, Mizusawa H, Nagao S, Ishikawa K. Temporal Relationship between Impairment of Cerebellar Motor Learning and Deterioration of Ataxia in Patients with Cerebellar Degeneration. Cerebellum (London, England). 2023.04; 23 (4): 1280-1292. ( PubMed, DOI )

Li F, Ichinose K, Ishibashi S, Yamamoto S, Iwasawa E, Suzuki M, Yoshida-Tanaka K, Yoshioka K, Nagata T, Hirabayashi H, Mogushi K, Yokota T. Preferential delivery of lipid-ligand conjugated DNA/RNA heteroduplex oligonucleotide to ischemic brain in hyperacute stage. Molecular therapy : the journal of the American Society of Gene Therapy. 2023.04; 31 (4): 1106-1122. ( PubMed, DOI )

Yanagidaira M, Yoshioka K, Nagata T, Nakao S, Miyata K, Yokota T. Effects of combinations of gapmer antisense oligonucleotides on the target reduction. Molecular biology reports. 2023.04; 50 (4): 3539-3546. ( PubMed, DOI )

Miyashita A, Kobayashi M, Yokota T, Zochodne DW. Diabetic Polyneuropathy: New Strategies to Target Sensory Neurons in Dorsal Root Ganglia. International journal of molecular sciences. 2023.03; 24 (6): ( PubMed, DOI )

Jia C, Lei Mon SS, Yang Y, Katsuyama M, Yoshida-Tanaka K, Nagata T, Yoshioka K, Yokota T. Change of intracellular calcium level causes acute neurotoxicity by antisense oligonucleotides via CSF route. Molecular therapy. Nucleic acids. 2023.03; 31 182-196. ( PubMed, DOI )

Ohara M, Hirata K, Hallett M, Matsubayashi T, Chen Q, Kina S, Shimano K, Hirakawa A, Yokota T, Hattori T. Long-term levodopa ameliorates sequence effect in simple, but not complex walking in early Parkinson's disease patients. Parkinsonism & related disorders. 2023.03; 108 105322. ( PubMed, DOI )

Koide T, Mandai S, Kitaoka R, Matsuki H, Chiga M, Yamamoto K, Yoshioka K, Yagi Y, Suzuki S, Fujiki T, Ando F, Mori T, Susa K, Iimori S, Naito S, Sohara E, Rai T, Yokota T, Uchida S. Circulating Extracellular Vesicle-Propagated microRNA Signature as a Vascular Calcification Factor in Chronic Kidney Disease. Circulation research. 2023.02; 132 (4): 415-431. ( PubMed, DOI )

Amano A, Sanjo N, Araki W, Anraku Y, Nakakido M, Matsubara E, Tomiyama T, Nagata T, Tsumoto K, Kataoka K, Yokota T. Peripheral administration of nanomicelle-encapsulated anti-Aβ oligomer fragment antibody reduces various toxic Aβ species in the brain. Journal of nanobiotechnology. 2023.01; 21 (1): 36. ( PubMed, DOI )

Aiba I, Hayashi Y, Shimohata T, Yoshida M, Saito Y, Wakabayashi K, Komori T, Hasegawa M, Ikeuchi T, Tokumaru AM, Sakurai K, Murayama S, Hasegawa K, Uchihara T, Toyoshima Y, Saito Y, Yabe I, Tanikawa S, Sugaya K, Hayashi K, Sano T, Takao M, Sakai M, Fujimura H, Takigawa H, Adachi T, Hanajima R, Yokota O, Miki T, Iwasaki Y, Kobayashi M, Arai N, Ohkubo T, Yokota T, Mori K, Ito M, Ishida C, Tanaka M, Idezuka J, Kanazawa M, Aoki K, Aoki M, Hasegawa T, Watanabe H, Hashizume A, Niwa H, Yasui K, Ito K, Washimi Y, Mukai E, Kubota A, Toda T, Nakashima K, J-VAC study group. Clinical course of pathologically confirmed corticobasal degeneration and corticobasal syndrome. Brain communications. 2023; 5 (6): fcad296. ( PubMed, DOI )

Matsuda H, Okita K, Motoi Y, Mizuno T, Ikeda M, Sanjo N, Murakami K, Kambe T, Takayama T, Yamada K, Suehiro T, Matsunaga K, Yokota T, Tateishi U, Shigemoto Y, Kimura Y, Chiba E, Kawashima T, Tomo Y, Tachimori H, Kimura Y, Sato N. Clinical impact of amyloid PET using (18)F-florbetapir in patients with cognitive impairment and suspected Alzheimer's disease: a multicenter study. Annals of nuclear medicine. 2022.12; 36 (12): 1039-1049. ( PubMed, DOI )

Matsuda Hiroshi, Okita Kyoji, Motoi Yumiko, Mizuno Toshiki, Ikeda Manabu, Sanjo Nobuo, Murakami Koji, Kambe Taiki, Takayama Toshiki, Yamada Kei, Suehiro Takashi, Matsunaga Keiko, Yokota Takanori, Tateishi Ukihide, Shigemoto Yoko, Kimura Yukio, Chiba Emiko, Kawashima Takahiro, Tomo Yui, Tachimori Hisateru, Kimura Yuichi, Sato Noriko. 認知障害およびAlzheimer病疑い患者への18F-florbetapirによるアミロイドPET検査が臨床に及ぼす影響　多施設共同研究(Clinical impact of amyloid PET using 18F-florbetapir in patients with cognitive impairment and suspected Alzheimer's disease: a multicenter study) Annals of Nuclear Medicine. 2022.12; 36 (12): 1039-1049. ( ichushi )

Ohara M, Sanjo N, Kanouchi T, Yokota T. Entrapment partly participates in the longitudinal progression of neuropathy with anti-MAG antibodies. Revue neurologique. 2022.11; 179 (1-2): 118-122. ( PubMed, DOI )

Chen Q, Hattori T, Tomisato H, Ohara M, Hirata K, Yokota T, Alzheimer's Disease Neuroimaging Initiative. Turning and multitask gait unmask gait disturbance in mild-to-moderate multiple sclerosis: Underlying specific cortical thinning and connecting fibers damage. Human brain mapping. 2022.11; 44 (3): 1193-1208. ( PubMed, DOI )

Goto A, Yamamoto S, Igari T, Matsumoto SI, Chisaki I, Iida K, Nakayama M, Oda A, Kakoi Y, Uchida A, Miyata K, Nishikawa M, Nagata T, Kusuhara H, Yokota T, Hirabayashi H. Quantitative Model Analysis and Simulation of Pharmacokinetics and Malat1 RNA Knockdown Effect After Systemic Administration of Cholesterol-conjugated DNA/RNA Heteroduplex Oligonucleotide Crossing Blood-Brain Barrier of Mice. The Journal of pharmacology and experimental therapeutics. 2022.10; 384 (1): 197-204. ( PubMed, DOI )

Zeniya S, Sanjo N, Kuwahara H, Ishikawa K, Higashi M, Matsunaga A, Yoneda M, Mizusawa Ho, Yokota T. Spinocerebellar Ataxia Type 31 Exacerbated by Anti-amino Terminal of Alpha-enolase Autoantibodies(タイトル和訳中) Internal Medicine. 2022.09; 61 (18): 2793-2796. ( ichushi )

Winklehner M, Bauer J, Endmayr V, Schwaiger C, Ricken G, Motomura M, Yoshimura S, Shintaku H, Ishikawa K, Tsuura Y, Iizuka T, Yokota T, Irioka T, Höftberger R. Paraneoplastic Cerebellar Degeneration With P/Q-VGCC vs Yo Autoantibodies. Neurology(R) neuroimmunology & neuroinflammation. 2022.07; 9 (4): e200006. ( PubMed, DOI )

Yokote H, Miyazaki Y, Toru S, Nishida Y, Hattori T, Niino M, Sanjo N, Yokota T. High-efficacy therapy reduces subcortical grey matter volume loss in Japanese patients with relapse-onset multiple sclerosis: A 2-year cohort study. Mult Scler Relat Disord. 2022.07; 67 104077. ( PubMed, DOI )

Kaburagi H, Nagata T, Enomoto M, Hirai T, Ohyagi M, Ihara K, Yoshida-Tanaka K, Ebihara S, Asada K, Yokoyama H, Okawa A, Yokota T. Systemic DNA/RNA heteroduplex oligonucleotide administration for regulating the gene expression of dorsal root ganglion and sciatic nerve. Molecular therapy. Nucleic acids. 2022.06; 28 910-919. ( PubMed, DOI )

Kana Tamaki,Yoichiro Nishida,Nobuo Sanjo,Takanori Yokota. A patient with generalized myasthenia gravis facing an impending crisis triggered by early fast-acting treatment Clinical and Experimental Neuroimmunology. 2022.05; 13 99-101. ( DOI )

Tamaki Kana, Nishida Yoichiro, Sanjo Nobuo, Yokota Takanori. A patient with generalized myasthenia gravis facing an impending crisis triggered by early fast-acting treatment(タイトル和訳中) Clinical and Experimental Neuroimmunology. 2022.05; 13 (2): 99-101. ( ichushi )

Matsubayashi T, Akaza M, Hayashi Y, Hamaguchi T, Satoh K, Kosami K, Ae R, Kitamoto T, Yamada M, Shimohata T, Yokota T, Sanjo N. Specific electroencephalogram features in the very early phases of sporadic Creutzfeldt-Jakob disease. J Neurol Sci. 2022.04; 437 120265. ( PubMed, DOI )

Uematsu M, Mikami K, Nakamura A, Takahashi R, Yokota T, Hirokawa K, Uchihara T. Parallel gold enhancement of quantum dots 565/655 for double-labelling correlative light and electron microscopy on human autopsied samples. Sci Rep. 2022.04; 12 (1): 6113. ( PubMed, DOI )

Bannawongsil T, Yamada A, Nakamura A, Uchihara T, Yokota T. Neuronal internalization of immunoglobulin G injected into the mouse brain by a novel absorption strategy to avoid unwanted interaction with immune complex using centrifugal filtration. Histochemistry and cell biology. 2022.04; ( PubMed, DOI )

Noda Kotaro, Nosaka Nobuyuki, Hara Nobuhiro, Yokota Takanori, Shigemitsu Hidenobu, Takahashi Hideo. 「関連痛」に注意する必要がある　食道穿孔の診断を隠し遅延させた急性心筋梗塞の1症例(We Should Pay Attention to "Referred Pain": A Case of Acute Myocardial Infarction That Masked and Delayed the Diagnosis of Esophageal Perforation) Internal Medicine. 2022.04; 61 (8): 1295-1298. ( ichushi )

Taniguchi K, Yamamoto F, Amamo A, Tamaoka A, Sanjo N, Yokota T, Kametani F, Araki W. Amyloid-β oligomers interact with NMDA receptors containing GluN2B subunits and metabotropic glutamate receptor 1 in primary cortical neurons: Relevance to the synapse pathology of Alzheimer's disease. Neurosci Res. 2022.03; ( PubMed, DOI )

Iwase R, Kanouchi T, Yoshii T, Ishiguro T, Hirai T, Okawa A, Yokota T, Sanjo N. Diverging pathophysiology in superficial siderosis with proximal upper limb amyotrophy. J Neurol Sci. 2022.03; 436 120248. ( PubMed, DOI )

Miyashita A, Kobayashi M, Ishibashi S, Nagata T, Chandrasekahr A, Zochodne DW, Yokota T. The Role of Long Non-coding RNA MALAT1 in Diabetic Polyneuropathy and the Impact of its Silencing in the Dorsal Root Ganglion by a DNA/RNA Heteroduplex Oligonucleotide. Diabetes. 2022.03; 71 (6): 1299-1312. ( PubMed, DOI )

Yamada A, Nishida Y, Wake K, Nakamura A, Sakamaki Y, Kuwahara H, Uchihara T, Yokota T. Serial ultrathin sections to identify ultrastructural localization of GLUT1 molecules in vesicles in brain endothelial cells-correlative light and electron microscopy in depth. Microscopy (Oxford, England). 2022.02; 71 (2): 124-131. ( PubMed, DOI )

Nishi R, Ohyagi M, Nagata T, Mabuchi Y, Yokota T. Regulation of activated microglia and macrophages by systemically administered DNA/RNA heteroduplex oligonucleotides. Mol Ther. 2022.02; 30 (6): 2210-23. ( PubMed, DOI )

Aoki H, Higashi M, Okita M, Ando N, Murayama S, Ishikawa K, Yokota T. Thymidine Kinase 2 and Mitochondrial Protein COX I in the Cerebellum of Patients with Spinocerebellar Ataxia Type 31 Caused by Penta-nucleotide Repeats (TTCCA)_n. Cerebellum . 2022.01; 22 (1): 70-84. ( PubMed, DOI )

Yoshii T, Hirai T, Egawa S, Hashimoto M, Matsukura Y, Inose H, Sanjo N, Yokota T, Okawa A. Case Report: Dural Dissection With Ventral Spinal Fluid-Filled Collection in Superficial Siderosis: Insights Into the Pathology From Anterior-Approached Surgical Cases. Front Neurol. 2022; 13 919280. ( PubMed, DOI )

Zeniya S, Sanjo N, Kuwahara H, Ishikawa K, Higashi M, Matsunaga A, Yoneda M, Mizusawa H, Yokota T. Spinocerebellar Ataxia Type 31 Exacerbated by Anti-amino Terminal of Alpha-enolase Autoantibodies. Internal medicine (Tokyo, Japan). 2022; 61 (18): 2793-2796. ( PubMed, DOI )

Eiichiro Amano, Tomokatsu Yoshida, Ikuko Mizuta, Jun Oyama, Shingo Sakashita, Syunsuke Ueyama, Akira Machida, Takanori Yokota. Activation of a Cryptic Splice Site of GFAP in a Patient With Adult-Onset Alexander Disease. Neurol Genet. 2021.12; 7 (6): e626. ( PubMed, DOI )

Masaki Ohyagi, Tetsuya Nagata,Kensuke Ihara, Kie Yoshida-Tanaka, Rieko Nishi, Haruka Miyata, Aya Abe,Yo Mabuchi, Chihiro Akazawa, Takanori Yokota. DNA/RNA heteroduplex oligonucleotide technology for regulating lymphocytes in vivo. Nat Commun. 2021.12; 12 (1): 7344. ( PubMed, DOI )

Tohnai G, Nakamura R, Atsuta N, Nakatochi M, Hayashi N, Ito D, Watanabe H, Watanabe H, Katsuno M, Izumi Y, Taniguchi A, Kanai K, Morita M, Kano O, Kuwabara S, Oda M, Abe K, Aoki M, Aiba I, Okamoto K, Mizoguchi K, Ishihara T, Kawata A, Yokota T, Hasegawa K, Nagano I, Yabe I, Tanaka F, Kuru S, Hattori N, Nakashima K, Kaji R, Sobue G, Japanese Consortium for Amyotrophic Lateral Sclerosis Research (JaCALS).. Mutation screening of the DNAJC7 gene in Japanese patients with sporadic amyotrophic lateral sclerosis. Neurobiol Aging. 2021.12; 113 131-136. ( PubMed, DOI )

Yagi Yohsuke, Asami Yutaro, Kyoya Mitsuki, Yokota Takanori. Cerebral venous sinus thrombosis after mRNA-based COVID-19 vaccination. Neurol　Sci. 2021.11; ( PubMed, DOI )

Yoichiro Nishida,Taro Ishiguro, Takanori Yokota. Tap-Elicited Clonus of the Biceps and Triceps Brachii. JAMA Neurol. 2021.11; 79 (2): 194. ( PubMed, DOI )

Takayuki Kuroda, Miho Akaza, Kazunori Miki, Shoko Fujii, Yousuke Yagi, Tadashi Kanouchi, Nobuo Sanjo, Kazutaka Sumita, Takanori Yokota. Sacral dural arteriovenous fistula mimicking multiple mononeuropathy. Clin Neurol Neurosurg. 2021.10; 210 106993. ( PubMed, DOI )

Yurie Nose, Ikuko Uwano, Ukihide Tateishi, Makoto Sasaki, Takanori Yokota, Nobuo Sanjo. Quantitative clinical and radiological recovery in post-operative patients with superficial siderosis by an iron chelator. J Neurol. 2021.10; 269 (5): 2539-2548. ( PubMed, DOI )

Kokoro Ozaki, Takashi Irioka, Toshiki Uchihara, Akane Yamada, Ayako Nakamura, Takamasa Majima, Susumu Igarashi, Hiroshi Shintaku, Mayumi Yakeishi, Yukio Tsuura, Yasushi Okazaki, Kinya Ishikawa, Takanori Yokota. Neuropathology of SCA34 showing widespread oligodendroglial pathology with vacuolar white matter degeneration: a case study. Acta neuropathol commun. 2021.10; 9 (1): 172. ( PubMed, DOI )

Kotaro Noda, Nobuyuki Nosaka, Nobuhiro Hara, Takanori Yokota, Hidenobu Shigemitsu, Hideo Takahashi. We Should Pay Attention to "Referred Pain" - A Case of Acute Myocardial Infarction that Masked and Delayed the Diagnosis of Esophageal Perforation. Intern Med. 2021.09; 61 (8): 1295-1298. ( PubMed, DOI )

Tetsuya Nagata, Chrissa A. Dwyer, Kie Yoshida-Tanaka, Kensuke Ihara, Masaki Ohyagi, Hidetoshi Kaburagi, Haruka Miyata, Satoe Ebihara, Kotaro Yoshioka, Takashi Ishii, Kanjiro Miyata, Kenichi Miyata, Berit Powers, Tomoko Igari, Syunsuke Yamamoto, Naoto Arimura, Hideki Hirabayashi, Toshiki Uchihara, Rintaro Iwata Hara, Takeshi Wada, C. Frank Bennett, Punit P. Seth, Frank Rigo and Takanori Yokota. Cholesterol-functionalized DNA/RNA heteroduplexes cross the blood-brain barrier and knock down genes in the rodent CNS. Nat Biotechnol. 2021.08; ( PubMed, DOI )

Hidenori Homma, Hikari Tanaka, Meihua Jin, Xiaocen Jin, Yong Huang, Yuki Yoshioka, Christian Jf Bertens, Kohei Tsumaki, Kanoh Kondo, Hiroki Shiwaku, Kazuhiko Tagawa, Hiroyasu Akatsu, Naoki Atsuta, Masahisa Katsuno, Katsutoshi Furukawa, Aiko Ishiki, Masaaki Waragai, Gaku Ohtomo, Atsushi Iwata, Takanori Yokota, Haruhisa Inoue, Hiroyuki Arai, Gen Sobue, Masaki Sone, Kyota Fujita, Hitoshi Okazawa. DNA damage in embryonic neural stem cell determines FTLDs' fate via early-stage neuronal necrosis. Life Sci Alliance. 2021.07; 4 (7): ( PubMed, DOI )

Motohiro Suzuki, Satoru Ishibashi, Eri Iwasawa , Takahiro Oguma, Yasuhiro Saito, Fuying Li, Shinichi Otsu, Keiko Ichinose, Kotaro Yoshioka, Tetsuya Nagata, Takanori Yokota. Effective silencing of miR-126 after ischemic stroke by means of intravenous α-tocopherol-conjugated heteroduplex oligonucleotide in mice. Sci Rep. 2021.07; 11 (1): 14237. ( PubMed, DOI )

Kazumasa Kawata, Hideyuki Koga, Kunikazu Tsuji, Kazumasa Miyatake, Yusuke Nakagawa, Takanori Yokota, Ichiro Sekiya, Hiroki Katagiri . Extracellular vesicles derived from mesenchymal stromal cells mediate endogenous cell growth and migration via the CXCL5 and CXCL6/CXCR2 axes and repair menisci. Stem cell research & therapy. 2021.07; 12 (1): 414. ( PubMed, DOI )

Shinya Akiko, Takahashi Makoto, Sato Nozomu, Nishida Yoichiro, Inaba Akira, Inaji Motoki, Yokota Takanori, Orimo Satoshi. Oculo-dento-digital Dysplasia Presenting as Spastic Paraparesis Which Was Successfully Treated by Intrathecal Baclofen Therapy(和訳中) Internal Medicine. 2021.07; 60 (14): 2301-2305. ( ichushi )

Ken Asada, Fumika Sakaue, Tetsuya Nagata, Ji-Chun Zhang, Kie Yoshida-Tanaka, Aya Abe, Makiko Nawa, Kazutaka Nishina , Takanori Yokota. Short DNA/RNA heteroduplex oligonucleotide interacting proteins are key regulators of target gene silencing. Nucleic Acids Res.. 2021.05; 49 (9): 4864-4876. ( PubMed, DOI )

Yoichiro Nishida, Takanori Yokota. Reversible reduction of dopamine transporter uptake in a case of hydrocephalus. Ann Neurol. 2021.05; ( PubMed, DOI )

Kotaro Noda,Yosuke Yagi, Takanori Yokota. Evaluation of the risk factors predicting thrombotic complications associated with intravenous immunoglobulin therapy in neuroimmunological diseases Neurol Sci.. 2021.04; 42 (12): 5321-5326. ( PubMed, DOI )

Nobuo Sanjo, Yurie Nose, Shouhei Miyamoto, Yukiko Shishido-Hara, Tatsuya Saito, Tetsuya Fukuda, Kurara Yamamoto, Daisuke Kobayashi, Takanori Yokota. Early pathological JC virus lesions in a patient without any MRI-based indications Inten Med. 2021.04; 60 (8): 1279-1282. ( ichushi )

Ono D, Asada K, Yui D, Sakaue F, Yoshioka K, Nagata T, Yokota T. Separation-related rapid nuclear transport of DNA/RNA heteroduplex oligonucleotide: unveiling distinctive intracellular trafficking. Molecular therapy. Nucleic acids. 2021.03; 23 1360-1370. ( PubMed, DOI )

Hiroaki Yokote, Shuta Toru, Yoichiro Nishida, Takaaki Hattori, Nobuo Sanjo, Takanori Yokota . Serum amyloid A level correlates with T2 lesion volume and cortical volume in patients with multiple sclerosis. J Neuroimmunol. 2021.02; 351 577466. ( PubMed, DOI )

Asami Yutaro, Nagata Tetsuya, Yoshioka Kotaro, Kunieda Taiki, Yoshida-Tanaka Kie, Bennett C. Frank, Seth Punit P., Yokota Takanori. Efficient Gene Suppression by DNA/DNA Double-Stranded Oligonucleotide In Vivo. Mol Ther. 2021.02; 29 (2): 838-847. ( PubMed, DOI )

Akiko Shinya, Makoto Takahashi, Nozomu Sato, Yoichiro Nishida, Akira Inaba, Motoki Inaji, Takanori Yokota, Satoshi Orimo. A case of oculo-dento-digital dysplasia presenting as spastic paraparesis which was successfully treated by intrathecal baclofen therapy. Intern Med. 2021.02; 60 (14): 2301-2305. ( PubMed, DOI )

Mitsuru Watanabe, Yuri Nakamura, Shinya Sato, Masaaki Niino, Hikoaki Fukaura, Masami Tanaka, Hirofumi Ochi, Takashi Kanda, Yukio Takeshita, Takanori Yokota, Yoichiro Nishida, Makoto Matsui, Shigemi Nagayama, Susumu Kusunoki, Katsuichi Miyamoto, Masanori Mizuno, Izumi Kawachi, Etsuji Saji, Takashi Ohashi, Shun Shimohama, Shin Hisahara, Kazutoshi Nishiyama, Takahiro Iizuka, Yuji Nakatsuji, Tatsusada Okuno, Kazuhide Ochi, Akio Suzumura, Ken Yamamoto, Yuji Kawano, Shoji Tsuji, Makoto Hirata, Ryuichi Sakate, Tomonori Kimura, Yuko Shimizu, Akiko Nagaishi, Kazumasa Okada, Fumie Hayashi, Ayako Sakoda, Katsuhisa Masaki, Koji Shinoda, Noriko Isobe, Takuya Matsushita, Jun-Ichi Kira . HLA genotype-clinical phenotype correlations in multiple sclerosis and neuromyelitis optica spectrum disorders based on Japan MS/NMOSD Biobank data. Sci rep. 2021.01; 11 (1): 607. ( PubMed, DOI )

Mitsuru Naito, Hiroyuki Chaya, Kazuko Toh, Beob Soo Kim, Kotaro Hayashi, Shigeto Fukushima, Tetsuya Nagata, Takanori Yokota, Kazunori Kataoka, Kanjiro Miyata. Structural tuning of oligonucleotides for enhanced blood circulation properties of unit polyion complexes prepared from two-branched poly(ethylene glycol)-block-poly(l-lysine). J control Release . 2021.01; 330 812-820. ( PubMed, DOI )

Matsubayashi T, Akaza M, Hayashi Y, Hamaguchi T, Yamada M, Shimohata T, Yokota T, Sanjo N. Focal sharp waves are a specific early-stage marker of the MM2-cortical form of sporadic Creutzfeldt-Jakob disease. Prion. 2020.12; 14 (1): 207-213. ( PubMed, DOI )

Takahashi S, Sanjo N, Miyamoto S, Hattori T, Oyama J, Tateishi U, Yokota T. Width of the third ventricle as a highly-sensitive biomarker in chronic progressive neuro-Behçet's disease. J Neurol Sci. 2020.12; 421 117284. ( PubMed, DOI )

Akaza M, Kawabata S, Ozaki I, Miyano Y, Watanabe T, Adachi Y, Sekihara K, Sumi Y, Yokota T. Noninvasive measurement of sensory action currents in the cervical cord by magnetospinography. Clin Neurophysiol. 2020.12; 132 (2): 382-391. ( PubMed, DOI )

Sugita Y, Nishida Y, Ishibashi S, Yokota T. Convexity Subarachnoid Hemorrhage Soon after Starting a Direct Oral Anticoagulant in 2 Patients with Acute Infarction. J Stroke Cerebrovasc Dis .. 2020.11; 29 (11): 105216. ( PubMed, DOI )

Hirata K, Yokota T, Miura Y. Teaching-Neuroimages: Parkinsonism secondary to a metastatic lesion involving the substantia nigra. Neurology. 2020.11; 96 (13): e1800-e1801. ( PubMed, DOI )

Sanjo N, Nose Y, Miyamoto S, Shishido-Hara Y, Saito T, Fukuda T, Yamamoto K, Kobayashi D, Yokota T. Early Pathological JC Virus Lesions in a Patient without any MRI-based Indications. Intern Med. 2020.11; 60 (8): 1279-1282. ( PubMed, DOI )

Yokoyama H, Hirai T, Nagata T, Enomoto M, Kaburagi H, Leiyo L, Motoyoshi T, Yoshii T, Okawa A, Yokota T. DNA Microarray Analysis of Differential Gene Expression in the Dorsal Root Ganglia of Four Different Neuropathic Pain Mouse Models. J Pain Res. 2020.11; 13 3031-3043. ( PubMed, DOI )

Yuko Yamagishi, Motoi Kuwahara, Hidekazu Suzuki, Masahiro Sonoo, Satoshi Kuwabara, Takanori Yokota, Kyoichi Nomura, Atsuro Chiba, Ryuji Kaji, Takashi Kanda, Ken-Ichi Kaida, Tatsuro Mutoh, Ryo Yamasaki, Hiroshi Takashima, Makoto Matsui, Kazutoshi Nishiyama, Gen Sobue, Susumu Kusunoki. Serum IgG anti-GD1a antibody and mEGOS predict outcome in Guillain-Barré syndrome. J Neurol Neurosurg Psychiatry. 2020.10; 91 (12): 1339-1342. ( PubMed, DOI )

Kishimoto Y, Nakagawa O, Fujii A, Yoshioka K, Nagata T, Yokota T, Hari Y, Obika S. 2',4'-BNA/LNA with 9-(2-Aminoethoxy)-1,3-diaza-2-oxophenoxazine Efficiently Forms Duplexes and Has Enhanced Enzymatic Resistance*. Chemistry . 2020.10; 27 (7): 2427-2438. ( PubMed, DOI )

Abe T, Yokota T, Fukushima A, Kakutani N, Katayama T, Shirakawa R, Maekawa S, Nambu H, Obata Y, Yamanashi K, Nakano I, Takada S, Yokota I, Okita K, Kinugawa S, Anzai T. Type 2 diabetes is an independent predictor of lowered peak aerobic capacity in heart failure patients with non-reduced or reduced left ventricular ejection fraction. Cardiovascular diabetology. 2020.09; 19 (1): 142. ( PubMed, DOI )

Iwase R, Irioka T, Igarashi S, Ayabe J, Yokota T. Intracranial dural arteriovenous fistula mimicking neuromyelitis optica spectrum disorder: A case report. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 2020.08; 29 (8): 105007. ( PubMed, DOI )

Tai Otani, Takashi Irioka, Susumu Igarashi, Kimihiko Kaneko, Toshiyuki Takahashi, Takanori Yokota. Self-remitting cerebral cortical encephalitis associated with myelin oligodendrocyte glycoprotein antibody mimicking acute viral encephalitis: A case report. Mult Scler Relat Disord. 2020.06; 41 102033. ( PubMed, DOI )

Kosei Hirata, Takaaki Hattori, Satoko Kina, Qingmeng Chen, Masahiro Ohara, Takanori Yokota. Striatal Dopamine Denervation Impairs Gait Automaticity in Drug-Naïve Parkinson's Disease Patients. Mov. Disord.. 2020.06; 35 (6): 1037-1045. ( PubMed, DOI )

Ryo Iwase, Taro Ishiguro, Kyohei Fujita, Satoru Ishibashi, Takanori Yokota. Dupilumab for Atopic Dermatitis, a Possible Risk Factor of Juvenile Ischemic Stroke: A Case Report. J Stroke Cerebrovasc Dis. 2020.06; 29 (6): 104763. ( PubMed, DOI )

Hirata K, Kobayashi M, Miyashita A, Yokota T. Steroid-responsive myositis in a patient with Sjögren's syndrome and refractory peripheral neuropathy. Neurological sciences . 2020.05; 41 (5): 1303-1305. ( PubMed, DOI )

Jinbing Xie, Daniel Gonzalez-Carter, Theofilus A Tockary, Noriko Nakamura, Yonger Xue, Makoto Nakakido, Hiroki Akiba, Anjaneyulu Dirisala, Xueying Liu, Kazuko Toh, Tao Yang, Zengtao Wang, Shigeto Fukushima, Junjie Li, Sabina Quader, Kouhei Tsumoto, Takanori Yokota, Yasutaka Anraku, Kazunori Kataoka. Dual-Sensitive Nanomicelles Enhancing Systemic Delivery of Therapeutically Active Antibodies Specifically into the Brain. ACS Nano. 2020.05; 14 (6): 6729-6742. ( PubMed, DOI )

Masahiro Ohara, Takaaki Hattori, Takanori Yokota. Progressive supranuclear palsy often develops idiopathic normal pressure hydrocephalus-like MRI features. Eur. J. Neurol.. 2020.05; 27 (10): 1930-1936. ( PubMed, DOI )

Teruhiko Sekiguchi, Satoru Ishibashi, Jo Sasame, Jun-Ichi Mukae, Kotaro Noda, Hiroaki Tanaka, Koh Yamamoto, Yasunori Takemoto, Jiro Kumagai, Takanori Yokota. Recurrent stroke due to quasi-moyamoya disease associated with POEMS syndrome: An autopsy case. J. Neurol. Sci.. 2020.02; 412 116738. ( PubMed, DOI )

Nishida Y, Takahashi YK, Kanai T, Nose Y, Ishibashi S, Sanjo N, Uzawa A, Oda F, Ozawa Y, Kuwabara S, Noguchi E, Suzuki S, Nakahara J, Suzuki N, Ogawa T, Yokoyama K, Hattori N, Konno S, Fujioka T, Kawaguchi N, Hatanaka Y, Sonoo M, Kaneko J, Ogino M, Nishiyama K, Nomura K, Yokota T. Safety of tapering tacrolimus dose in patients with well-controlled anti-acetylcholine receptor antibody-positive myasthenia gravis. European journal of neurology. 2020.01; 27 (1): 100-104. ( PubMed, DOI )

Lei Mon SS, Yoshioka K, Jia C, Kunieda T, Asami Y, Yoshida-Tanaka K, Piao W, Kuwahara H, Nishina K, Nagata T, Yokota T. Highly efficient gene silencing in mouse brain by overhanging-duplex oligonucleotides via intraventricular route. FEBS letters. 2020.01; 594 (9): 1413-1423. ( PubMed, DOI )

Rintaro Iwata Hara, Kotaro Yoshioka, Takanori Yokota. DNA-RNA Heteroduplex Oligonucleotide for Highly Efficient Gene Silencing. Methods Mol. Biol.. 2020; 2176 113-119. ( PubMed, DOI )

Yanagidaira M, Nishida Y, Yokota T. Temporal correlation between serum CH₅₀ level and symptom severity of myasthenia gravis during eculizumab therapy. Clinical neurology and neurosurgery. 2019.12; 189 105630. ( PubMed, DOI )

Masaki Ohyagi, Takashi Irioka, Takuya Ohkubo, Satoru Ishibashi, Yuko K Takahashi, Eiichiro Amano, Akira Machida, Hiroya Kuwahara, Takanori Yokota. Intrathecal IgG Synthesis and Persistent Inflammation Are Associated with White Matter Lesions in HIV-negative Patients with Cryptococcal Meningoencephalitis. Intern. Med.. 2019.11; 58 (21): 3077-3082. ( PubMed, DOI )

Yanagidaira M, Hattori T, Emoto H, Kiyosawa M, Yokota T. Optic perineuritis with anti-myelin oligodendrocyte glycoprotein antibody. Multiple sclerosis and related disorders. 2019.10; 38 101444. ( PubMed, DOI )

Ohara M, Sanjo N, Hattori T, Oyama J, Hamada M, Ozaki K, Yokota T. Olivary hypertrophy improved by steroid treatment: Two case reports with unique presentations. Journal of neuroimmunology. 2019.09; 334 577003. ( PubMed, DOI )

Yoshioka K, Kunieda T, Asami Y, Guo H, Miyata H, Yoshida-Tanaka K, Sujino Y, Piao W, Kuwahara H, Nishina K, Hara RI, Nagata T, Wada T, Obika S, Yokota T. Highly efficient silencing of microRNA by heteroduplex oligonucleotides. Nucleic acids research. 2019.08; 47 (14): 7321-7332. ( PubMed, DOI )

Momoko Ebashi, Shuta Toru, Ayako Nakamura, Satoshi Kamei, Takanori Yokota, Katsuiku Hirokawa, Toshiki Uchihara. Detection of AD-specific four repeat tau with deamidated asparagine residue 279-specific fraction purified from 4R tau polyclonal antibody Acta Neuropathologica. 2019.07; 138 (1): 163-166.

Fujita K, Tanaka K, Yamagami H, Ide T, Ishiyama H, Sonoda K, Satow T, Takahashi JC, Ihara M, Koga M, Yokota T, Toyoda K. Detrimental Effect of Chronic Hypertension on Leptomeningeal Collateral Flow in Acute Ischemic Stroke. Stroke. 2019.07; 50 (7): 1751-1757. ( PubMed, DOI )

Shintaku H, Yamaguchi M, Toru S, Kitagawa M, Hirokawa K, Yokota T, Uchihara T. . Three-dimensional surface models of autopsied human brains constructed from multiple photographs by photogrammetry. PLoS One. 2019.07; 14 (7): ( DOI )

Head and Neck Cancer Study Group (HNCSG), Monden N, Asakage T, Kiyota N, Homma A, Matsuura K, Hanai N, Kodaira T, Zenda S, Fujii H, Tahara M, Yokota T, Akimoto T, Iwae S, Onitsuka T, Ogawa T, Okano S, Takahashi S, Shimizu Y, Yonezawa K, Hayashi R. A review of head and neck cancer staging system in the TNM classification of malignant tumors (eighth edition). Japanese journal of clinical oncology. 2019.07; 49 (7): 589-595. ( PubMed, DOI )

Otsu S, Ishibashi S, Ozaki K, Yokota T. Elevated lipid peaks during the recovery phase of Baló's concentric sclerosis: A case report. eNeurologicalSci. 2019.06; 15 100191. ( PubMed, DOI )

Ono D, Shishido-Hara Y, Mizutani S, Mori Y, Ichinose K, Watanabe M, Tanizawa T, Yokota T, Uchihara T, Fujigasaki H. Development of demyelinating lesions in progressive multifocal leukoencephalopathy (PML): Comparison of magnetic resonance images and neuropathology of post-mortem brain. Neuropathology : official journal of the Japanese Society of Neuropathology. 2019.06; 39 (4): 294-306. ( PubMed, DOI )

Hashiguchi S, Doi H, Kunii M, Nakamura Y, Shimuta M, Suzuki E, Koyano S, Okubo M, Kishida H, Shiina M, Ogata K, Hirashima F, Inoue Y, Kubota S, Hayashi N, Nakamura H, Takahashi K, Katsumoto A, Tada M, Tanaka K, Sasaoka T, Miyatake S, Miyake N, Saitsu H, Sato N, Ozaki K, Ohta K, Yokota T, Mizusawa H, Mitsui J, Ishiura H, Yoshimura J, Morishita S, Tsuji S, Takeuchi H, Ishikawa K, Matsumoto N, Ishikawa T, Tanaka F. Ataxic phenotype with altered Ca_V3.1 channel property in a mouse model for spinocerebellar ataxia 42. Neurobiology of disease. 2019.06; 130 104516. ( PubMed, DOI )

Guo L, Bertola DR, Takanohashi A, Saito A, Segawa Y, Yokota T, Ishibashi S, Nishida Y, Yamamoto GL, Franco JFDS, Honjo RS, Kim CA, Musso CM, Timmons M, Pizzino A, Taft RJ, Lajoie B, Knight MA, Fischbeck KH, Singleton AB, Ferreira CR, Wang Z, Yan L, Garbern JY, Simsek-Kiper PO, Ohashi H, Robey PG, Boyde A, Matsumoto N, Miyake N, Spranger J, Schiffmann R, Vanderver A, Nishimura G, Passos-Bueno MRDS, Simons C, Ishikawa K, Ikegawa S. Bi-allelic CSF1R Mutations Cause Skeletal Dysplasia of Dysosteosclerosis-Pyle Disease Spectrum and Degenerative Encephalopathy with Brain Malformation. American journal of human genetics. 2019.05; 104 (5): 925-935. ( PubMed, DOI )

Ozaki K, Ansai A, Nobuhara K, Araki T, Kubodera T, Ishii T, Higashi M, Sato N, Soga K, Mizusawa H, Ishikawa K, Yokota T. Prevalence and clinicoradiological features of spinocerebellar ataxia type 34 in a Japanese ataxia cohort. Parkinsonism & related disorders. 2019.05; 65 238-242. ( PubMed, DOI )

Uehara T, Choong CJ, Nakamori M, Hayakawa H, Nishiyama K, Kasahara Y, Baba K, Nagata T, Yokota T, Tsuda H, Obika S, Mochizuki H. Amido-bridged nucleic acid (AmNA)-modified antisense oligonucleotides targeting α-synuclein as a novel therapy for Parkinson's disease. Scientific reports. 2019.05; 9 (1): 7567. ( PubMed, DOI )

Nico J. Diedrich, James Surmeier, Toshiki Uchihara, Sten Grillner, Christopher G. Goetz. Parkinson's disease: Is it a consequence of human brain evolution? Movement Disorders. 2019.04; ３４ (４): ４５３-1531. ( PubMed, DOI )

Hirata K, Numasawa Y, Kobayashi Z, Yokota T. Bilateral Optic Tract Hyperintensity due to Pituitary Apoplexy. Internal medicine (Tokyo, Japan). 2019.04; 58 (8): 1185-1186. ( PubMed, DOI )

Rashaun S. Wilson, Navin Rauniyar, Fumika Sakaue, TuKiet T. Lam, Kenneth R. Williams, Angus C. Nairn. Development of Targeted Mass Spectrometry-Based Approaches for Quantitation of Proteins Enriched in the Postsynaptic Density (PSD) proteomes. 2019.04; 7 (2): ( PubMed, DOI )

Hashimoto S, Inaji M, Nariai T, Kobayashi D, Sanjo N, Yokota T, Ishii K, Taketoshi M. Usefulness of [¹¹C] Methionine PET in the Differentiation of Tumefactive Multiple Sclerosis from High Grade Astrocytoma. Neurologia medico-chirurgica. 2019.04; 59 (5): 176-183. ( PubMed, DOI )

Ebashi M, Toru S, Nakamura A, Kamei S, Yokota T, Hirokawa K, Uchihara T. Detection of AD-specific four repeat tau with deamidated asparagine residue 279-specific fraction purified from 4R tau polyclonal antibody. Acta neuropathologica. 2019.04; 138 (1): 163-166. ( PubMed, DOI )

Furukawa F, Ishikawa K, Yokota T, Sanjo N. Cross-Sectional Area Analysis of the Head of the Caudate Nucleus in Huntington's Disease. European neurology. 2019.04; 81 (1-2): 13-18. ( PubMed, DOI )

Sanjo N, Nose Y, Shishido-Hara Y, Mizutani S, Sekijima Y, Aizawa H, Tanizawa T, Yokota T. A controlled inflammation and a regulatory immune system are associated with more favorable prognosis of progressive multifocal leukoencephalopathy. Journal of neurology. 2019.02; 266 (2): 369-377. ( PubMed, DOI )

Suzuki S, Naito S, Numasawa Y, Asada M, Shoji N, Zeniya M, Takahashi D, Sato H, Iimori S, Nomura N, Sohara E, Okado T, Ishiwata Y, Nagata M, Rai T, Yokota T, Uchida S. Encephalopathy Induced by High Plasma and Cerebrospinal Fluid Ceftriaxone Concentrations in a Hemodialysis Patient. Internal medicine (Tokyo, Japan). 2019.02; 58 (12): 1775-1779. ( PubMed, DOI )

Maeda Y, Iwata Hara R, Nishina K, Yoshida-Tanaka K, Sakamoto T, Yokota T, Wada T. Artificial cationic peptides that increase nuclease resistance of siRNA without disturbing RNAi activity. Nucleosides, nucleotides & nucleic acids. 2019.01; 38 (5): 338-348. ( PubMed, DOI )

Amano E, Ozaki K, Ishibashi S, Sanjo N, Yokota T. Remarkable improvement in progressive multifocal leukoencephalopathy following acute pyelonephritis with bacteremia. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. 2019.01; 62 226-228. ( PubMed, DOI )

Takahashi K, Yanai S, Takisawa S, Kono N, Arai H, Nishida Y, Yokota T, Endo S, Ishigami A. Vitamin C and vitamin E double-deficiency increased neuroinflammation and impaired conditioned fear memory. Archives of biochemistry and biophysics. 2019.01; 663 120-128. ( PubMed, DOI )

Otani T, Irioka T, Takahashi YK, Soga K, Igarashi S, Kaneko K, Takahashi T, Yokota T. Two cases of late-onset neuromyelitis optica spectrum disorder initially presenting with isolated cerebral white matter lesions. eNeurologicalSci. 2018.12; 13 35-37. ( PubMed, DOI )

Ozaki K, Ohkubo T, Yamada T, Yoshioka K, Ichijo M, Majima T, Kudo S, Akashi T, Honda K, Ito E, Watanabe M, Sekine M, Hamagaki M, Eishi Y, Sanjo N, Ishibashi S, Mizusawa H, Yokota T. Progressive Encephalomyelitis with Rigidity and Myoclonus Resolving after Thymectomy with Subsequent Anasarca: An Autopsy Case Internal Medicine. 2018.12; 57 (23): 3451-3458. ( ichushi )

Miura M, Numasawa Y, Takahisa M, Ozaki K, Irioka T, Nishida Y, Ishibashi S, Yokota T. Levodopa-responsive truncal tremor in a patient with spinocerebellar ataxia type 3. Journal of the neurological sciences. 2018.09; 392 32-33. ( PubMed, DOI )

Miho Akaza*, Itaru Akaza, Tadashi Kanouchi, Tetsuo Sasano, Yuki Sumi, Takanori Yokota. Nerve conduction study of the association between glycemic variability and diabetes neuropathy. Diabetology &Metabolic Syndrome. 2018.09; 10 69. ( PubMed, DOI )

Zeniya S, Kuwahara H, Daizo K, Watari A, Kondoh M, Yoshida-Tanaka K, Kaburagi H, Asada K, Nagata T, Nagahama M, Yagi K, Yokota T. Angubindin-1 opens the blood-brain barrier in vivo for delivery of antisense oligonucleotide to the central nervous system. Journal of controlled release : official journal of the Controlled Release Society. 2018.08; 283 126-134. ( PubMed, DOI )

Yokote H, Kamata T, Toru S, Sanjo N, Yokota T. Brain volume loss is present in Japanese multiple sclerosis patients with no evidence of disease activity. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2018.07; 39 (10): 1713-1716. ( PubMed, DOI )

Sasaguri H, Nagata K, Sekiguchi M, Fujioka R, Matsuba Y, Hashimoto S, Sato K, Kurup D, Yokota T, Saido TC. Introduction of pathogenic mutations into the mouse Psen1 gene by Base Editor and Target-AID. Nature communications. 2018.07; 9 (1): 2892. ( PubMed, DOI )

Honda T, Nagao S, Hashimoto Y, Ishikawa K, Yokota T, Mizusawa H, Ito M. Tandem internal models execute motor learning in the cerebellum. Proceedings of the National Academy of Sciences of the United States of America. 2018.07; 115 (28): 7428-7433. ( PubMed, DOI )

Ozaki K, Ohkubo T, Yamada T, Yoshioka K, Ichijo M, Majima T, Kudo S, Akashi T, Honda K, Ito E, Watanabe M, Sekine M, Hamagaki M, Eishi Y, Sanjo N, Ishibashi S, Mizusawa H, Yokota T. Progressive Encephalomyelitis with Rigidity and Myoclonus Resolving after Thymectomy with Subsequent Anasarca: An Autopsy Case. Internal medicine (Tokyo, Japan). 2018.07; 57 (23): 3451-3458. ( PubMed, DOI )

Asada K, Ito K, Yui D, Tagaya H, Yokota T. Cytosolic Genomic DNA functions as a Natural Antisense. Scientific reports. 2018.06; 8 (1): 8551. ( PubMed, DOI )

Guo Huijia, Yoshioka Kotaro, Kunieda Taiki, Asami Yutaro, Miyata Haruka, Yoshida-Tanaka Kie, Nagata Tetsuya, Yokota Takanori. Efficacy of microRNA silencing by lipid-conjugated double-stranded antisense oligonucleotides(和訳中) Journal of Medical and Dental Sciences. 2018.06; 65 (2): 83-88. ( ichushi )

Li Fuying, Ishibashi Satoru, Iwasawa Eri, Suzuki Motohiro, Ichinose Keiko, Yokota Takanori. Upregulation of lipoprotein receptors on brain endothelial cells and neurons in the early phase of ischemic stroke in mice Journal of Medical and Dental Sciences. 2018.06; 65 (2): 59-71. ( ichushi )

Itaya Sakiko, Kobayashi Zen, Ozaki Kokoro, Sato Nozomu, Numasawa Yoshiyuki, Ishikawa Kinya, Yokota Takanori, Matsuda Hiroshi, Shintani Shuzo. Spinocerebellar Ataxia Type 31 with Blepharospasm Internal Medicine. 2018.06; 57 (11): 1651-1654. ( ichushi )

Misawa S, Kuwabara S, Sato Y, Yamaguchi N, Nagashima K, Katayama K, Sekiguchi Y, Iwai Y, Amino H, Suichi T, Yokota T, Nishida Y, Kanouchi T, Kohara N, Kawamoto M, Ishii J, Kuwahara M, Suzuki H, Hirata K, Kokubun N, Masuda R, Kaneko J, Yabe I, Sasaki H, Kaida KI, Takazaki H, Suzuki N, Suzuki S, Nodera H, Matsui N, Tsuji S, Koike H, Yamasaki R, Kusunoki S, Japanese Eculizumab Trial for GBS (JET-GBS) Study Group.. Safety and efficacy of eculizumab in Guillain-Barré syndrome: a multicentre, double-blind, randomised phase 2 trial. The Lancet. Neurology. 2018.06; 17 (6): 519-529. ( PubMed, DOI )

Iwasawa E, Ishibashi S, Suzuki M, Li F, Ichijo M, Miki K, Yokota T. Sphingosine-1-Phosphate Receptor 1 Activation Enhances Leptomeningeal Collateral Development and Improves Outcome after Stroke in Mice. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 2018.05; 27 (5): 1237-1251. ( PubMed, DOI )

Higashi M, Ozaki K, Hattori T, Ishii T, Soga K, Sato N, Tomita M, Mizusawa H, Ishikawa K, Yokota T. A diagnostic decision tree for adult cerebellar ataxia based on pontine magnetic resonance imaging. Journal of the neurological sciences. 2018.04; 387 187-195. ( PubMed, DOI )

Hattori T, Ito K, Nakazawa C, Numasawa Y, Watanabe M, Aoki S, Mizusawa H, Ishiai S, Yokota T. Structural connectivity in spatial attention network: reconstruction from left hemispatial neglect. Brain imaging and behavior. 2018.04; 12 (2): 309-323. ( PubMed, DOI )

Rintaro Iwata Hara, Yuki Hisada, Yusuke Maeda, Takanori Yokota, Takeshi Wada. Artificial cationic oligosaccharides for heteroduplex oligonucleotide-type drugs. Sci Rep. 2018.03; 8 (1): 4323. ( PubMed, DOI )

Amano E, Ozaki K, Egawa S, Suzuki M, Hirai T, Ishibashi S, Ohkubo T, Yoshii T, Okawa A, Yokota T. Dynamic spinal compression revealed by computed tomography myelography in overshunting-associated myelopathy: A case report. Medicine. 2018.03; 97 (10): e0082. ( PubMed, DOI )

Kuwahara H, Song J, Shimoura T, Yoshida-Tanaka K, Mizuno T, Mochizuki T, Zeniya S, Li F, Nishina K, Nagata T, Ito S, Kusuhara H, Yokota T. Modulation of blood-brain barrier function by a heteroduplex oligonucleotide in vivo. Scientific reports. 2018.03; 8 (1): 4377. ( PubMed, DOI )

Hiroki Yamada, Takahiro Takeda, Toshiki Uchihara, Shizuko Sato, Susumu Kirimura, Yuka Hirota, Makoto Kodama, Masanobu Kitagawa, Katsuiku Hirokawa, Takanori Yokota, Shuta Toru. Macroscopic Localized Subicular Thinning as a Potential Indicator of Amyotrophic Lateral Sclerosis. Eur. Neurol.. 2018.03; 79 (3-4): 200-205. ( PubMed, DOI )

Nishimaki K, Asada T, Ohsawa I, Nakajima E, Ikejima C, Yokota T, Kamimura N, Ohta S. Effects of Molecular Hydrogen Assessed by an Animal Model and a Randomized Clinical Study on Mild Cognitive Impairment. Current Alzheimer research. 2018.03; 15 (5): 482-492. ( PubMed, DOI )

Ito Y, Sanjo N, Hizume M, Kobayashi A, Ohgami T, Satoh K, Hamaguchi T, Yamada M, Kitamoto T, Mizusawa H, Yokota T. Biochemical features of genetic Creutzfeldt-Jakob disease with valine-to-isoleucine substitution at codon 180 on the prion protein gene. Biochemical and biophysical research communications. 2018.02; 496 (4): 1055-1061. ( PubMed, DOI )

Furukawa F, Sanjo N, Kobayashi A, Hamaguchi T, Yamada M, Kitamoto T, Mizusawa H, Yokota T. Specific amyloid-β42 deposition in the brain of a Gerstmann-Sträussler-Scheinker disease patient with a P105L mutation on the prion protein gene. Prion. 2018; 12 (5-6): 315-319. ( PubMed, DOI )

Hara Y, Mizobe Y, Miyatake S, Takizawa H, Nagata T, Yokota T, Takeda S, Aoki Y. Exon Skipping Using Antisense Oligonucleotides for Laminin-Alpha2-Deficient Muscular Dystrophy. Methods in molecular biology (Clifton, N.J.). 2018; 1828 553-564. ( PubMed, DOI )

Yuko Yamagishi, Hidekazu Suzuki, Masahiro Sonoo, Satoshi Kuwabara, Takanori Yokota, Kyoichi Nomura, Atsuro Chiba, Ryuji Kaji, Takashi Kanda, Kenichi Kaida, Shu-Ichi Ikeda, Tatsuro Mutoh, Ryo Yamasaki, Hiroshi Takashima, Makoto Matsui, Kazutoshi Nishiyama, Gen Sobue, Susumu Kusunoki. Markers for Guillain-Barré syndrome with poor prognosis: a multi-center study. J. Peripher. Nerv. Syst.. 2017.12; 22 (4): 433-439. ( PubMed, DOI )

Tetsuya Kanai, Akiyuki Uzawa, Yasunori Sato, Shigeaki Suzuki, Naoki Kawaguchi, Keiichi Himuro, Fumiko Oda, Yukiko Ozawa, Jin Nakahara, Norihiro Suzuki, Yuko K Takahashi, Satoru Ishibashi, Takanori Yokota, Takashi Ogawa, Kazumasa Yokoyama, Nobutaka Hattori, Shoko Izaki, Satoru Oji, Kyoichi Nomura, Juntaro Kaneko, Kazutoshi Nishiyama, Ichiro Yoshino, Satoshi Kuwabara. A clinical predictive score for postoperative myasthenic crisis. Ann. Neurol.. 2017.11; 82 (5): 841-849. ( PubMed, DOI )

Yajun Hu, Yuji Hashimoto, Takashi Ishii, Mamut Rayle, Kazumasa Soga, Nozomu Sato, Michi Okita, Miwa Higashi, Kokoro Ozaki, Hidehiro Mizusawa, Kinya Ishikawa, Takanori Yokota. Sequence configuration of spinocerebellar ataxia type 8 repeat expansions in a Japanese cohort of 797 ataxia subjects. J. Neurol. Sci.. 2017.11; 382 87-90. ( PubMed, DOI )

Shuta Toru, Tadashi Kanouchi, Takanori Yokota, Yosuke Yagi, Akira Machida, Takayoshi Kobayashi. Utility of Autonomic Function Tests to Differentiate Dementia with Lewy Bodies and Parkinson Disease with Dementia from Alzheimer Disease. Eur. Neurol.. 2017.11; 79 (1-2): 27-32. ( PubMed, DOI )

Yuki Kishimoto, Akane Fujii, Osamu Nakagawa, Tetsuya Nagata, Takanori Yokota, Yoshiyuki Hari, Satoshi Obika. Synthesis and thermal stabilities of oligonucleotides containing 2'-O,4'-C-methylene bridged nucleic acid with a phenoxazine base. Org. Biomol. Chem.. 2017.10; 15 (38): 8145-8152. ( PubMed, DOI )

Y Anraku, H Kuwahara, Y Fukusato, A Mizoguchi, T Ishii, K Nitta, Y Matsumoto, K Toh, K Miyata, S Uchida, K Nishina, K Osada, K Itaka, N Nishiyama, H Mizusawa, T Yamasoba, T Yokota, K Kataoka. Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain. Nat Commun. 2017.10; 8 (1): 1001. ( PubMed, DOI )

Nozomu Sato, Nozomi Toide, Mami Kizawa, Takuya Ohkubo, Satoru Ishibashi, Nobuo Sanjo, Takanori Yokota. Methotrexate-associated lymphoproliferative disorder in a patient with neuromyelitis optica spectrum disorder: An implication for pathogenesis mediated by Epstein-Barr virus. J. Neurol. Sci.. 2017.08; 379 219-221. ( PubMed, DOI )

Ohyagi M, Ishibashi S, Ohkubo T, Kobayashi Z, Mizusawa H, Yokota T, Emoto H, Kiyosawa M. Subacute Supranuclear Palsy in anti-Hu Paraneoplastic Encephalitis. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. 2017.07; 44 (4): 444-446. ( PubMed, DOI )

Yokote H, Kamata T, Toru S, Sanjo N, Yokota T. Serum retinol levels are associated with brain volume loss in patients with multiple sclerosis. Multiple sclerosis journal - experimental, translational and clinical. 2017.07; 3 (3): 2055217317729688. ( PubMed, DOI )

Taro Ishiguro, Nozomu Sato, Morio Ueyama, Nobuhiro Fujikake, Chantal Sellier, Akemi Kanegami, Eiichi Tokuda, Bita Zamiri, Terence Gall-Duncan, Mila Mirceta, Yoshiaki Furukawa, Takanori Yokota, Keiji Wada, J. Paul Taylor, Christopher E. Pearson, Nicolas Charlet-Berguerand, Hidehiro Mizusawa, Yoshitaka Nagai, and Kinya Ishikawa. Regulatory Role of RNA Chaperone TDP-43 for RNA Misfolding and Repeat-Associated Translation in SCA31. Neuron. 2017.04; 94 (1): 108-124. ( PubMed, DOI )

Numasawa Y, Hattori T, Ishiai S, Kobayashi Z, Kamata T, Kotera M, Ishibashi S, Sanjo N, Mizusawa H, Yokota T. Depressive disorder may be associated with raphe nuclei lesions in patients with brainstem infarction. Journal of affective disorders. 2017.04; 213 191-198. ( PubMed, DOI )

Higuma M, Sanjo N, Mitoma H, Yoneyama M, Yokota T. Whole-Day Gait Monitoring in Patients with Alzheimer's Disease: A Relationship between Attention and Gait Cycle. Journal of Alzheimer's disease reports. 2017.04; 1 (1): 1-8. ( PubMed, DOI )

Yokota Takanori. 肝外臓器におけるDNA/RNAヘテロ二本鎖オリゴヌクレオチド(HDO)の作用(The effect of DNA/RNA heteroduplex oligonucleotide (HDO) in extrahepatic organs) Journal of Pharmacological Sciences. 2017.03; 133 (3Suppl.): S43. ( ichushi )

Kazumasa Soga, Kinya Ishikawa, Tokuro Furuya, Tadatsune Iida, Tetsuo Yamada, Noboru Ando, Kiyobumi Ota, Hiromi Kanno-Okada, Shinya Tanaka, Masayuki Shintaku, Yoshinobu Eishi, Hidehiro Mizusawa, Takanori Yokota. Gene dosage effect in spinocerebellar ataxia type 6 homozygotes: A clinical and neuropathological study. J Neurol Sci. 2017.02; 373 321-328. ( PubMed, DOI )

Sakiko Chikazawa, Takaaki Hanafusa, Kokoro Ozaki, Takeshi Namiki, Maki Amano, Makiko Ueno, Shown Tokoro, Ken Igawa, Takefumi Sato, Kinya Ishikawa, Takanori Yokota, Hiroo Yokozeki. Incomplete Behçet's disease with calf muscle pain and MRI hyperintensity due to possible thrombophlebitis. Eur J Dermatol. 2017.02; 27 (1): 76-77. ( PubMed, DOI )

Keisuke Abe, Takuya Ohkubo, Takanori Yokota.. TDP-43 in the skin of amyotrophic lateral sclerosis patients. Journal of Medical and Dental Sciences. 2017.01; 64 (1): 9-17. ( PubMed, DOI )

Yagi Y, Ohkubo T, Kawaji H, Machida A, Miyata H, Goda S, Roy S, Hayashizaki Y, Suzuki H, Yokota T. Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes. Neuroscience letters. 2017.01; 636 48-57. ( PubMed, DOI )

Iwasawa E, Ohkubo T, Kanouchi T, Kanda T, Mizusawa H, Yokota T. Long-term Effects of Intravenous Cyclophosphamide in Combination with Mesna Provided Intravenously and via Bladder Perfusion in a Patient with Severe Multifocal Motor Neuropathy. Internal medicine (Tokyo, Japan). 2017; 56 (14): 1893-1896. ( PubMed, DOI )

Nobutaka Ishizu, Daishi Yui, Akira Hebisawa, Hidenori Aizawa, Wanpeng Cui, Yuko Fujita, Kenji Hashimoto, Itsuki Ajioka, Hidehiro Mizusawa, Takanori Yokota, Kei Watase. Impaired striatal dopamine release in homozygous Vps35 D620N knock-in mice. Hum. Mol. Genet.. 2016.10; 25 (20): 4507-4517. ( PubMed, DOI )

Ryo Yamasaki, Takuya Matsushita, Toshiyuki Fukazawa, Kazumasa Yokoyama, Kazuo Fujihara, Mieko Ogino, Takanori Yokota, Katsuichi Miyamoto, Masaaki Niino, Kyoichi Nomura, Ryo Tomioka, Masami Tanaka, Izumi Kawachi, Takashi Ohashi, Ken-Ichi Kaida, Makoto Matsui, Yuji Nakatsuji, Hirofumi Ochi, Hikoaki Fukaura, Takashi Kanda, Akiko Nagaishi, Kanae Togo, Hidehiro Mizusawa, Hiroyuki Murai, Jun-Ichi Kira. Efficacy of intravenous methylprednisolone pulse therapy in patients with multiple sclerosis and neuromyelitis optica. Mult. Scler.. 2016.09; 22 (10): 1337-1348. ( PubMed, DOI )

Eri Iwasawa, Masahiko Ichijo, Satoru Ishibashi, Takanori Yokota. Acute development of collateral circulation and therapeutic prospects in ischemic stroke. Neural Regen Res. 2016.03; 11 (3): 368-371. ( PubMed, DOI )

Enomoto M, Hirai T, Kaburagi H, Yokota T. Efficient Gene Suppression in Dorsal Root Ganglia and Spinal Cord Using Adeno-associated Virus Vectors Encoding Short-Hairpin RNA. Methods Mol Biol. 2016; 1364 277-290.

Yamada K, Kobayashi H, Bo R, Takahashi T, Purevsuren J, Hasegawa Y, Taketani T, Fukuda S, Ohkubo T, Yokota T, Watanabe M, Tsunemi T, Mizusawa H, Takuma H, Shioya A, Ishii A, Tamaoka A, Shigematsu Y, Sugie H, Yamaguchi S. Clinical, biochemical and molecular investigation of adult-onset glutaric acidemia type II: Characteristics in comparison with pediatric cases. Brain Dev. 2016; 38 (3): 293-301.

Yutaro Asami, Kotaro Yoshioka, Kazutaka Nishina, Tetsuya Nagata, Takanori Yokota. Drug delivery system of therapeutic oligonucleotides. Drug Discov Ther. 2016; 10 (5): 256-262. ( PubMed, DOI )

M Ichijo, E Iwasawa, Y Numasawa, K Miki, S Ishibashi, M Tomita, H Tomimitsu, T Kamata, H Fujigasaki, S Shintani, H Mizusawa. Significance of Development and Reversion of Collaterals on MRI in Early Neurologic Improvement and Long-Term Functional Outcome after Intravenous Thrombolysis for Ischemic Stroke. AJNR Am J Neuroradiol. 2015.10; 36 (10): 1839-1845. ( PubMed, DOI )

Yoneyama M, Mitoma H, Higuma M, Sanjo N, Yokota T, Terashi H. Ambulatory Gait Behavior in Patients with Dementia: A Comparison with Parkinson's Disease. IEEE Trans Neural Syst Rehabil Eng. 2015.09;

Nakamaura Y, Ae R, Takumi I, Sanjo N, Kitamoto T, Yamada M, Mizusawa H. Descriptive epidemiology of prion disease in Japan: 1999-2012. J Epidemiol. 2015; 25 (1): 8-14.

Kimura K, Morita H, Daimon M, Kawata T, Nakao T, Lee SL, Hirokawa M, Ebihara A, Nakajima T, Ozawa T, Yonemochi Y, Aida I, Motoyoshi Y, Mikata T, Uchida I, Komori T, Kitao R, Nagata T, Takeda S, Komaki H, Segawa K, Takenaka K, Komuro I . Prognostic impact of venous thromboembolism in patients with Duchenne muscular dystrophy: Prospective multicenter 5-year cohort study. Int J Cardiol. 2015; 191 178-180.

Masaki Y, Inde T, Nagata T, Tanihata J, Kanamori T, Seio K, Takeda S, Sekine M. Enhancement of exon skipping in mdx52 mice by 2’-O-methyl-2-thioribothymidine incorporation into phosphorothioate oligonucleotides. Med Chem Commun. 2015; 6 630-633.

Colangelo CM, Ivosev G, Chung L, Abbott T, Shifman M, Sakaue F, Cox D, Kitchen RR, Burton L, Tate SA, Gulcicek E, Bonner R, Rinehart J, Nairn AC, Williams KR. Development of a highly automated and multiplexed targeted proteome pipeline and assay for 112 rat brain synaptic proteins. Proteomics. 2015; 15 (7): 1202-1214.

Yagi Y, Yokote H, Watanabe Y, Amino T, Kamata T, Kusunoki S. Taste impairment in Miller Fisher syndrome. Neurol Sci. 2015; 36 (5): 809-810.

Ozaki K, Sanjo N, Ishikawa K, Higashi M, Hattori T, Tanuma N, Miyata R, Hayashi M, Yokota T, Okawa A, Mizusawa H. Elevation of 8-hydroxy-2′-deoxyguanosine in the cerebrospinal fluid of three patients with superficial siderosis. Neurol Clin Neurosci. 2015; 3 (3): 108-110.

Ohyagi M, Nakamura K, Watanabe M, Fujigasaki H. Embolic stroke during apixaban therapy for left atrial appendage thrombus. J Stroke Cerebrovasc Dis. 2015; 24 (4): e101-102.

Ishibashi K, Miura Y, Ishikawa K, Ishii K, Ishiwata K. Decreased metabotropic glutamate receptor type 1 availability in a patient with spinocerebellar ataxia type 6: A (11)C-ITMM PET study. J Neurol Sci. 2015; 355 (1-2): 202-205.

Yabe I, Matsushima M, Yoshida K, Ishikawa K, Shirai S, Takahashi I, Sasaki H. Rare frequency of downbeat positioning nystagmus in spinocerebellar ataxia type 31. J Neurol Sci. 2015; 350 (1-2): 90-92.

Obayashi M, Stevanin G, Synofzik M, Monin ML, Duyckaerts C, Sato N, Streichenberger N, Vighetto A, Desestret V, Tesson C, Wichmann HE, Illig T, Huttenlocher J, Kita Y, Izumi Y, Mizusawa H, Schöls L, Klopstock T, Brice A, Ishikawa K, Dürr A. Spinocerebellar ataxia type 36 exists in diverse populations and can be caused by a short hexanucleotide GGCCTG repeat expansion. J Neurol Neurosurg Psychiatry. 2015; 86 (9): 986-995.

Echigoya Y, Aoki Y, Miskew B, Panesar D, Touznik A, Nagata T, Tanihata J, Nakamura A, Nagaraju K, Yokota T. Long-term efficacy of systemic multiexon skipping targeting dystrophin exons 45-55 with a cocktail of vivo-morpholinos in mdx52 mice. Mol Ther Nucleic Acids. 2015; 4 e225.

Azuma R, Ishikawa K, Hirata K, Hashimoto Y, Takahashi M, Ishii K, Inaba A, Yokota T, Orimo S. A novel mutation of PDE8B Gene in a Japanese family with autosomal-dominant striatal degeneration. Mov Disord. 2015; 30 (14): 1964-1967.

Yui D, Nishida Y, Nishina T, Mogushi K, Tajiri M, Ishibashi S, Ajioka I, Ishikawa K, Mizusawa H, Murayama S, Yokota T. Enhanced Phospholipase A2 Group 3 Expression by Oxidative Stress Decreases the Insulin-Degrading Enzyme. PLoS One. 2015; 10 (12): e0143518.

Murakami M, Nishina K, Watanabe C, Yoshida-Tanaka K, Piao W, Kuwahara H, Horikiri Y, Miyata K, Nishiyama N, Kataoka K, Yoshida M, Mizusawa H, Yokota T. Enteral siRNA delivery technique for therapeutic gene silencing in the liver via the lymphatic route. Sci Rep. 2015; 5 17035.

Nishina K, Piao W, Yoshida-Tanaka K, Sujino Y, Nishina T, Yamamoto T, Nitta K, Yoshioka K, Kuwahara H, Yasuhara H, Baba T, Ono F, Miyata K, Miyake K, Seth PP, Low A, Yoshida M, Bennett CF, Kataoka K, Mizusawa H, Obika S, Yokota T. DNA/RNA heteroduplex oligonucleotide for highly efficient gene silencing. Nat Commun. 2015; 6 7969.

Nishina T, Numata J, Nishina K, Yoshida-Tanaka K, Nitta K, Piao W, Iwata R, Ito S, Kuwahara H, Wada T, Mizusawa H, Yokota T. Chimeric Antisense Oligonucleotide Conjugated to α- Tocopherol. Mol Ther Nucleic Acids. 2015; 4 e220.

Iwata R, Nakayama F, Hirochi S, Sato K, Piao W, Nishina K, Yokota T, Wada T. Synthesis and properties of vitamin E analog-conjugated neomycin for delivery of RNAi drugs to liver cells. Bioorg Med Chem Lett. 2015; 25 (4): 815-819.

Hattori T, Arai A, Yokota T, Imadome K, Tomimitsu H, Miura O, Mizusawa H. Immune-mediated Neuropathy with Epstein-Barrvirus-positive T-cell Lymphoproliferative Disease. Intern Med. 2015; 54 (1): 69-73.

Yoshioka K, Watanabe K, Zeniya S, Ito Y, Hizume M, Kanazawa T, Tomita M, Ishibashi S, Miake H, Tanaka H, Yokota T, Mizusawa H. A Score for Predicting Paroxysmal Atrial Fibrillation in Acute Stroke Patients: iPAB Score. J Stroke Cerebrovasc Dis. 2015; 24 (10): 2263-2269.

Ozaki K, Doi H, Mitsui J, Sato N, Iikuni Y, Majima T, Yamane K, Irioka T, Ishiura H, Doi K, Morishita S, Higashi M, Sekiguchi T, Koyama K, Ueda N, Miura Y, Miyatake S, Matsumoto N, Yokota T, Tanaka F, Tsuji S, Mizusawa H, Ishikawa K. A Novel Mutation in ELOVL4 Leading to Spinocerebellar Ataxia (SCA) With the Hot Cross Bun Sign but Lacking Erythrokeratodermia: A Broadened Spectrum of SCA34. JAMA Neurol. 2015; 72 (7): 797-805.

Mizutani S, Usui N, Yokota T, Mizusawa H, Taira M, Katsuyama N. Depth perception from moving cast shadow in macaque monkey. Behav Brain Res. 2015; 288 63-70.

Hashimoto Y, Honda T, Matsumura K, Nakao M, Soga K, Katano K, Yokota T, Mizusawa H, Nagao S, Ishikawa K. Quantitative evaluation of human cerebellum-dependent motor learning through prism adaptation of hand-reaching movement. PLoS One. 2015; 10 (3): e0119376.

Yokote H, Nose Y, Ishibashi S, Tanaka K, Takahashi T, Fujihara K, Yokota T, Mizusawa H. Spinal cord ring enhancement in patients with neuromyelitis optica. Acta Neurol Scand. 2015; 132 (1): 37-41.

Winkler EA, Nishida Y, Sagare AP, Rege SV, Bell RD, Perlmutter D, Sengillo JD, Hillman S, Kong P, Nelson AR, Sullivan JS, Zhao Z, Meiselman HJ, Wenby RB, Soto J, Abel ED, Makshanoff J, Zuniga E, De Vivo DC, Zlokovic BV. GLUT1 reductions exacerbate Alzheimer's disease vasculo-neuronal dysfunction and degeneration. Nat Neurosci. 2015; 18 (4): 521-530.

Aikawa T, Mogushi K, Iijima-Tsutsui K, Ishikawa K, Sakurai M, Tanaka H, Mizusawa H, Watase K. Loss of MyD88 alters neuroinflammatory response and attenuates early Purkinje cell loss in a spinocerebellar ataxia type 6 mouse model. Hum Mol Genet. 2015; 24 (17): 4780-4791.

Pedroso JL, Abrahao A, Ishikawa K, Raskin S, de Souza PV, de Rezende Pinto WB, Braga-Neto P, de Albuquerque MV, Mizusawa H, Barsottini OG. When should we test patients with familial ataxias for SCA31? A misdiagnosed condition outside Japan? J Neurol Sci. 2015; 355 (1-2): 206-208.

Ohmori H, Hara A, Ishikawa K, Mizusawa H, Ando Y. Clinical characteristics of combined cases of spinocerebellar ataxia types 6 and 31. J Neurogenet. 2015; 29 (2-3): 80-4.

Mitsui J, Matsukawa T, Sasaki H, Yabe I, Matsushima M, Dürr A, Brice A, Takashima H, Kikuchi A, Aoki M, Ishiura H, Yasuda T, Date H, Ahsan B, Iwata A, Goto J, Ichikawa Y, Nakahara Y, Momose Y, Takahashi Y, Hara K, Kakita A, Yamada M, Takahashi H, Onodera O, Nishizawa M, Watanabe H, Ito M, Sobue G, Ishikawa K, Mizusawa H, Kanai K, Hattori T, Kuwabara S, Arai K, Koyano S, Kuroiwa Y, Hasegawa K, Yuasa T, Yasui K, Nakashima K, Ito H, Izumi Y, Kaji R, Kato T, Kusunoki S, Osaki Y, Horiuchi M, Kondo T, Murayama S, Hattori N, Yamamoto M, Murata M, Satake W, Toda T, Filla A, Klockgether T, Wüllner U, Nicholson G, Gilman S, Tanner CM, Kukull WA, Stern MB, Lee VM, Trojanowski JQ, Masliah E, Low PA, Sandroni P, Ozelius LJ, Foroud T, Tsuji S. Variants associated with Gaucher disease in multiple system atrophy. Ann Clin Transl Neurol. 2015; 2 (4): 417-426.

Ozaki K, Irioka T, Ishikawa K, Mizusawa H. CADASIL with a novel NOTCH3 mutation (Cys478Tyr). J Stroke Cerebrovasc Dis. 2015; 24 (3): e61-62.

Nishida Y, Ueda A, Ando Y, Ichikawa T. Skin biopsy-based diagnosis of CADASIL with atypical MRI findings. Intern Med. 2015; 54 (5): 537-538.

Takenouchi T, Ohyagi M, Torii C, Kosaki R, Takahashi T, Kosaki K. Porencephaly in a fetus and HANAC in her father: variable expression of COL4A1 mutation. Am J Med Genet A. 2015; 167A (1): 156-158.

Masahiko Ichijo, Satoru Ishibashi, Fuying Li, Daishi Yui, Kazunori Miki, Hidehiro Mizusawa, Takanori Yokota. Sphingosine-1-Phosphate Receptor-1 Selective Agonist Enhances Collateral Growth and Protects against Subsequent Stroke. PLoS ONE. 2015; 10 (9): e0138029. ( PubMed, DOI )

Matsubayashi Taiki, Ae Ryusuke, Kosami Koki, Tsukamoto Tadashi, Satoh Katsuya, Hamaguchi Tsuyoshi, Furukawa Fumiko, Takao Masaki, Kitamoto Tetsuyuki, Nakamura Yosikazu, Mizusawa Hidehiro, Yamada Masahito, Yokota Takanori, Sanjo Nobuo. PRNP遺伝子にP105L変異を認めるプリオン病の臨床病理学的解析(Clinicopathological analysis in prion disease with PRNP P105L mutation). Dementia Japan 2023.10.01

Matsubayashi Taiki, Ae Ryusuke, Kosami Koki, Tsukamoto Tadashi, Satoh Katsuya, Hamaguchi Tsuyoshi, Furukawa Fumiko, Takao Masaki, Kitamoto Tetsuyuki, Nakamura Yosikazu, Mizusawa Hidehiro, Yamada Masahito, Yokota Takanori, Sanjo Nobuo. PRNP遺伝子にP105L変異を認めるプリオン病の臨床病理学的解析(Clinicopathological analysis in prion disease with PRNP P105L mutation). Dementia Japan 2023.10.01

Ishihara Tomohiko, Ikenaka Kensuke, Takahashi Yuji, Yokota Takanori, Ishikawa Kinya, Hirano Makito, Nagai Yoshitaka, Onodera Osamu. AJA030-002　ポリグルタミン病に対するタンパク質凝集阻害剤の第II相試験(AJA030-002:Phase II Study of a Protein Aggregation Inhibitor for Polyglutamine Disease). 臨床神経学 2023.09.01

Ichinose Keiko, Li Fuying, Ishibashi Satoru, Iwasawa Eri, Suzuki Motohiro, Yoshida Kie, Yoshioka Kotaro, Nagata Tetsuya, Mogushi Kaoru, Yokota Takanori. 脂質結合DNA/RNAヘテロ2本鎖オリゴヌクレオチドの急性虚血脳への効果的な送達(Effective delivery of lipid conjugated DNA/RNA heteroduplex oligonucleotide to acute ischemic brain). 臨床神経学 2023.09.01

常 詩晨, 田中 敏博, 稲澤 譲治, 水澤 英洋, 三條 伸夫, 横田 隆徳, 石川 欽也. 神経疾患の遺伝的リスク評価. 臨床神経学 2023.09.01

Yokota Takanori. 神経疾患に関する遺伝子治療と細胞療法　神経疾患を標的としたDNA/RNAヘテロ2本鎖オリゴヌクレオチド(Gene and cell therapy for neurological diseases　DNA/RNA heteroduplex oligonucleotides for neurological diseases). 臨床神経学 2023.09.01

Hattori Takaaki, Kitsuka Narumi, Sanjo Nobuo, Oyama Jun, Yoshii Toshitaka, Okawa Atsushi, Yokota Takanori. 硬膜閉鎖後の表在性シデローシスにおける前側頭葉の逆説的なMRI増悪(Paradoxical MRI exacerbation in anterior temporal lobe in superficial siderosis after dural closure). 臨床神経学 2023.09.01

Ono Daisuke, Kawai Honami, Kuwahara Hiroya, Yokota Takanori. 機械学習アプリケーションによる腓腹神経生検の自動whole slide解析(Automated Whole Slide Analysis of Sural Nerve Biopsy by Machine Learning Application). 臨床神経学 2023.09.01

Miura Motoki, Sakaue Fumika, Matsuno Hirokazu, Morita Kento, Hara Rintaro, Yokota Takanori. 核酸結合によるTDP-43の空間分布を介した溶解性の制御(Regulation of TDP-43 solubility via its spatial organization by nucleic acid binding). 臨床神経学 2023.09.01

Yokote Hiroaki, Miyazaki Yusei, Toru Shuta, Nishida Yoichiro, Hattori Takaaki, Niino Masaaki, Sanjo Nobuo, Yokota Takanori. 日本人多発性硬化症患者の脳容積減少を抑制する有効性の高い治療法(High-efficacy therapy reduces brain volume loss in Japanese patients with multiple sclerosis). 臨床神経学 2023.09.01

Kuroda Takayuki, Yoshioka Kotaro, Su Su Lei Mon , Sakamoto Toshihiro, Katsuyama Maho, Yoshida-Tanaka Kie, Iwata-Hara Rintaro, Yamaguchi Takao, Nagata Tetsuya, Obika Satoshi, Yokota Takanori. アンチセンスオリゴヌクレオチドの神経毒性を克服するための化学的改良の開発(Development of chemical modifications to overcome neurotoxicity of antisense oligonucleotide). 臨床神経学 2023.09.01

Iwase Ryo, Ishiguro Taro, Hasegawa Juri, Iwata Hara Rintaro, Nagata Tetsuya, Yokota Takanori. RNA-DNAヘテロG4構造誘導ASOを用いたDMDエクソンスキッピングに対する新戦略(A new strategy for DMD exon skipping with RNA-DNA hetero-G4 structure inducing ASOs). 臨床神経学 2023.09.01

Yanagidaira Mitsugu, Nagata Testuya, Hasegawa Juri, Ishii Satoshi, Ebihara Satoe, Yokota Takanori. PMO/RNAヘテロ2本鎖を用いたCNSにおけるスプライス制御の新規技術(Novel technology for splice modulation in CNS by PMO/RNA heteroduplex). 臨床神経学 2023.09.01

Amano Eiichiro, Raveney Ben, Yokota Takanori, Yamamura Takashi, Oki Shinji. NRP-1+Th細胞はCD11c+B細胞を増殖させ脳反応性自己抗体の強力な供給源となる(NRP-1+Th cells expand CD11c+B cells that are potent source of brain reactive autoantibodies). 臨床神経学 2023.09.01

Yokota T. Blood-Brain-Barrier(BBB)penetrating DNA/RNA Heteroduplex Oligonucleotide regulating CNS genes by systemic adminissssssssstration. ANA2022 2022.10.23 CHICAGO

Yokota T. Blood-Brain-Barrier penetrating DNA/RNA Heteroduplex Oligonuclotide (HDO)can regulate genes of microglia and lymphocytes by systemic administration. The 34th annual meeting of the Japanese Society for Neuroimmunology 2022.10.21 長崎

Hirata Kosei, Matsuoka Kiwamu, Tagai Kenji, Endo Hironobu, Kokubo Naomi, Tatebe Harutsugu, Zhang Hong, Shinotoh Hitoshi, Takahata Keisuke, Ono Maiko, Obata Takayuki, Kawamura Kazunori, Zhang Ming-rong, Shimada Hitoshi, Tokuda Takahiko, Yokota Takanori, Takado Yuhei, Higuchi Makoto. Altered brain energy metabolism related to astrocytes in tauopathies(タイトル和訳中). 臨床神経学 2022.10.01

Hirata Kosei, Matsuoka Kiwamu, Tagai Kenji, Endo Hironobu, Kokubo Naomi, Tatebe Harutsugu, Zhang Hong, Shinotoh Hitoshi, Takahata Keisuke, Ono Maiko, Obata Takayuki, Kawamura Kazunori, Zhang Ming-Rong, Shimada Hitoshi, Tokuda Takahiko, Yokota Takanori, Takado Yuhei, Higuchi Makoto. タウオパチーにおけるアストロサイトに関連した脳エネルギー代謝の変化(Altered brain energy metabolism related to astrocytes in tauopathies). 臨床神経学 2022.10.01

Okamoto Tomoko, Sato Wakiro, Lin Youwei, Shimizu Yuko, Nishida Yoichiro, Yokota Takanori, Ishizuka Takami, Nakamura Harumasa, Takahashi Yuji, Yamamura Takashi. 糖脂質OCH-NCNP1　多発性硬化症患者を対象とした第II相臨床試験プロトコール(Glycolipid OCH-NCNP1: Protocol of Phase II Clinical Trial for Patients with Multiple Sclerosis). 臨床神経学 2022.10.01

Ishihara Tomohiko, Ikenaka Kensuke, Takahashi Yuji, Yokota Takanori, Ishikawa Kinya, Hirano Makito, Nagai Yoshitaka, Onodera Osamu. ポリグルタミン病に対するタンパク質凝集阻害剤の第II相試験(Phase II Study of a Protein Aggregation Inhibitor for Polyglutamine Disease). 臨床神経学 2022.10.01

Sanjo Nobuo, Amano Akiko, Araki Wataru, Anraku Yasutaka, Nakakido Makoto, Matsubara Etsuro, Hirata Kousei, Nagata Tetsuya, Tsumoto Kouhei, Kataoka Kazunori, Yokota Takanori. ナノミセル化抗アミロイドβオリゴマー断片抗体のAD病態における有効性(Efficacy of nanomicelle-encapsulated anti-amyloid β oligomer fragment antibody in AD pathology). 臨床神経学 2022.10.01

Kawabata Sakino, Toide Nozomi, Nagata Tetsuya, Yoshida-Tanaka Kie, Ihara Kensuke, Yokota Takanori. トリコサン酸結合DNA/RNAヘテロ二重鎖オリゴヌクレオチドはマウスの筋において非常に効率的である(Tricosanoic acid conjugated DNA/RNA heteroduplex oligonucleotide is highly efficient in mouse muscle). 臨床神経学 2022.10.01

Hasegawa Juri, Nagata Tetsuya, Ihara Kensuke, Tanihata Jun, Yokota Takanori. エクソンスキッピングの新しい治療法としての脂質結合ヘテロ二重鎖オリゴヌクレオチドの開発(Development of Lipid-conjugated heteroduplex oligonucleotide as a new treatment for exon skipping). 臨床神経学 2022.10.01

Higashi Miwa, Okita Michi, Sato Nozomu, Aoki Hanako, Komatsu Takumi, Asaka Meiko, Yanagihara Dai, Yokota Takanori, Ishikawa Kinya. SCA31ペンタヌクレオチド反復配列BACトランスジェニックマウスの運動表現型(Motor phenotype of BAC transgenic mice with SCA31 pentanucleotide repeats). 臨床神経学 2022.10.01

Aoki Hanako, Higashi Miwa, Okita Michi, Ishikawa Kinya, Yokota Takanori. Pentanucleotide repeat(TTCCA)nによるSCA31の小脳におけるTK2の発現と機能(Expression and function of TK2 in the cerebellum of SCA31 caused by pentanucleotide repeat (TTCCA)n). 臨床神経学 2022.10.01

Nishi Rieko, Ohyagi Masaki, Nagata Tetsuya, Mabuchi Yo, Yokota Takanori. DNA/RNAヘテロ二重鎖オリゴヌクレオチドによる活性化ミクログリアとマクロファージの制御(Regulation of activated microglia and macrophages by DNA/RNA heteroduplex oligonucleotides). 臨床神経学 2022.10.01

Sano Tatsuhiko, Nagata Tetsuya, Ebihara Satoe, Yoshida-Tanaka Kie, Mochizuki Hideki, Hasegawa Masato, Yokota Takanori. ASOの局所投与はマウスにおける異常αシヌクレイン病態の伝播を防ぐ(Local administration of ASO prevents the propagation of abnormal α-synuclein pathology in mice). 臨床神経学 2022.10.01

Hirata Kosei, Matsuoka Kiwamu, Tagai Kenji, Endo Hironobu, Kokubo Naomi, Tatebe Harutsugu, Zhang Hong, Shinotoh Hitoshi, Takahata Keisuke, Ono Maiko, Obata Takayuki, Kawamura Kazunori, Zhang Ming-Rong, Shimada Hitoshi, Tokuda Takahiko, Yokota Takanori, Takado Yuhei, Higuchi Makoto. タウオパチーにおけるアストロサイトに関連した脳エネルギー代謝の変化(Altered brain energy metabolism related to astrocytes in tauopathies). 臨床神経学 2022.10.01

Amano Eiichiro, Sato Wakiro, Yamaguchi Hiromi, Yokota Takanori, Yamamura Takashi. 視神経脊髄炎患者におけるCD11chigh B細胞の増加(CD11chigh B cell expansion in patients with neuromyelitis optica). 臨床神経学 2022.10.01

Aoki H,Higashi M,Okita M,Ishikawa K,Yokota T. Expression and function of TK2 in the cerebellum of SCA31 caused by pentanucleotide repeat (TTCCA). 第６３回日本神経学会学術大会 2022.05.20 東京

Higashi M,Okita M,Sato N,Aoki H,Komatsu T,Asaka M,Yanagihara D,Yokota T,Ishikawa K. Motor phenotype of BAC transgenic mice with SCA31 pentanucleotide repeats. 第６３回日本神経学会学術大会 2022.05.20 東京

Sanjo N,Amano A,Araki W,Anraku Y,Nakakido M,Matsubara EHirata K,Nagata T,Tsumoto K,Kataoka K,Yokota T,. Efficacy of nanomicelle-encapsulated anti-amyloid β oligomer fragment antibody in AD pathology. 第６３回日本神経学会学術大会 2022.05.19 東京

Kawabata S,Toide N,Nagata T,Yoshida-tanaka K,Ihara K,Yokota T,. Tricosanoic acid conjugated DNA/RNA heteroduplex oligonucleotide is highly efficient in mouse muscle. 第６３回日本神経学会学術大会 2022.05.19 東京

Amano E,Sato W,Yamaguchi H,Yokota T,Yamamura T. CD11chigh B cell expansion in patients with neuromyelitis optica. 第６３回日本神経学会学術大会 2022.05.19 東京

Ishihara T,Ikenaka K,Takahashi Y,Yokota T,Ishikawa K,Hirano M,Nagai Y,Onodera O. Phase Ⅱ study of a Protein Aggregation Inhibitor for Polyglutamine Disease. 第６３回日本神経学会学術大会 2022.05.19 東京

Nishi R,Ohyagi M,Nagata T,Mabuchi Y,Yokota T. Regulation of activated microglia and macrophages by DNA/RNA heteroduplex oligonucleotides. 第６３回日本神経学会学術大会 2022.05.18 東京

Hirata K,Matsuoka K,Tagai K,Endo H,Kokubo N,Tatebe H,Zhang H,Shinotoh H,Takahata K,Ono M,Obata T,Kawamura K,Zhang M,Shimada H,Tokuda T,Yokota T,Takado Y,Higuchi M. Aitered brain energy metabolism related to astrocytes in tauopathies. 第６３回日本神経学会学術大会 2022.05.18 東京

Hasegawa J,Nagata T,Ihara K,Tanihata J,Yokota T. Development of Lipid-conjugated heteroduplex oligonucleotide as a new treatment for exon skipping. 第６３回日本神経学会学術大会 2022.05.18 東京

Sano T,Nagata T,Ebihara S,Yoshida-tanaka K,Mochizuki H,Hasegawa M,Yokota T. Local administration of ASO prevents the propagation of abnormal α-synuclein pathology in micein pathology in mice. 第６３回日本神経学会学術大会 2022.05.18 東京

Tamaki Kana, Nishida Yoichiro, Sanjo Nobuo, Yokota Takanori. A patient with generalized myasthenia gravis facing an impending crisis triggered by early fast-acting treatment(和訳中). Clinical and Experimental Neuroimmunology 2022.05.01

Noda K, Nosaka N, Hara N, Yokota T, Shigemitsu H, Takahashi H. We Should Pay Attention to "Referred Pain": A Case of Acute Myocardial Infarction That Masked and Delayed the Diagnosis of Esophageal Perforation(和訳中). Internal Medicine 2022.04.01

中村圭佑,金澤俊郎,関口輝彦,桑原宏哉,石川欽也,横田隆徳,西野一三,大久保卓哉. DNM2遺伝子新規変異を認めた中心核ミオパチーが疑われる76歳女性例. 2022.03.05

大谷 泰,赤座実穂,叶内 匡,夏井洋和,川端茂徳,渡部泰士,石田洸樹,宮野由貴,足立善昭,関原謙,横田隆徳,. 生体磁場計測装置を用いた単一の運動単位の電気活動評価. 第14回CBIR/ONSA/大学院セミナー共済　若手インスパイアシンポジウム 2022.02.17

Ohara M,Nagata T,Iwata Hara R,Takagi K,Sato K,Maeda Y,Wada T,Yokota T. Cationic oligopeptides enhance the therapeutic potential of ligand-conjug DNA/RNA heteroduplex . 第14回CBIR/ONSA/大学院セミナー共済　若手インスパイアシンポジウム 2022.02.17

Takanori Yokota. Development of heteroduplex oligonucleotides(HDO)for contral nervous system by systemic administration. PACIFICHEM 2021 2021.12.17 USA　web

Takaaki Hattori, Masahiro Ohara, Tatsuhiko Yuasa, Reo Azuma, Qingmeng Chen, Satoshi Orimo, Takanori Yokota. . Callosal angle at splenium is phenotypicmarker of idiopathic normal pressure hydrocephalus. The 15th Congress of the Movement Disorder Society of Japan 2021.07.02

Shinya Akiko, Takahashi Makoto, Sato Nozomu, Nishida Yoichiro, Inaba Akira, Inaji Motoki, Yokota Takanori, Orimo Satoshi. 髄腔内バクロフェン療法が成功した痙性不全対麻痺として現れた眼・歯・指異形成症(Oculo-dento-digital Dysplasia Presenting as Spastic Paraparesis Which Was Successfully Treated by Intrathecal Baclofen Therapy). Internal Medicine 2021.07.01

Shinya Akiko, Takahashi Makoto, Sato Nozomu, Nishida Yoichiro, Inaba Akira, Inaji Motoki, Yokota Takanori, Orimo Satoshi. 髄腔内バクロフェン療法が成功した痙性不全対麻痺として現れた眼・歯・指異形成症(Oculo-dento-digital Dysplasia Presenting as Spastic Paraparesis Which Was Successfully Treated by Intrathecal Baclofen Therapy). Internal Medicine 2021.07.01

Shinya Akiko, Takahashi Makoto, Sato Nozomu, Nishida Yoichiro, Inaba Akira, Inaji Motoki, Yokota Takanori, Orimo Satoshi. 髄腔内バクロフェン療法が成功した痙性不全対麻痺として現れた眼・歯・指異形成症(Oculo-dento-digital Dysplasia Presenting as Spastic Paraparesis Which Was Successfully Treated by Intrathecal Baclofen Therapy). Internal Medicine 2021.07.01

Shinya Akiko, Takahashi Makoto, Sato Nozomu, Nishida Yoichiro, Inaba Akira, Inaji Motoki, Yokota Takanori, Orimo Satoshi. 髄腔内バクロフェン療法が成功した痙性不全対麻痺として現れた眼・歯・指異形成症(Oculo-dento-digital Dysplasia Presenting as Spastic Paraparesis Which Was Successfully Treated by Intrathecal Baclofen Therapy). Internal Medicine 2021.07.01

Chunyan Jia，Kotaro Yoshioka，Su Su Lei Mon，Maho Katsuyama，Kie Tanaka-yoshida，Tetsuya Nagata，Takanori Yokota. Hetereoduplex oligonucleotiede mitigates various types of acute CNS toxicities via CSF route. 62nd Annual Meeting of the Japanese Society of Neurology  2021.05.21 Kyoto

Yurie Nose，Ikuko Uwano，Ukihide Tateishi，Makoto Sasaki，Takanori Yokota，Nobuo Sanjo. Clinical and radiological efficacy of deferiprone in post-operative superficial siderosis. 62nd Annual Meeting of the Japanese Society of Neurology  2021.05.20 Kyoto

Taiki Matsubayashi，Takaaki Hattori，Masahiro Ohara，Kosei Hirata，Qingmeng Chen，Sato ko Kina，Koji Morito，Kaoru Shimano，Takanori Yokota. Dopaminergic denervation in executive striatum predicts response to L-dopa in Parkinson's disease. 62nd Annual Meeting of the Japanese Society of Neurology  2021.05.20 Kyoto

Masahiro Ohara，Takaaki Hattori，Taiki Matsubayashi，Kosei Hirata，Qingmeng Chen，Satoko Kina，Koji Morito，Kaoru Shimano，Takanori Yokota. Inter-regional balance within striatum affects cognition and dual-task gait in Parkinson's disease. 62nd Annual Meeting of the Japanese Society of Neurology  2021.05.20 Kyoto

Takaaki Hattori, Richard Reynolds, Silvina Horovitz, Codrin Lungu, Eric Wassermann, Mark Hallett. Decreased functional integrity within striatum and sensorimotor network in Parkinson disease. 62nd Annual Meeting of the Japanese Society of Neurology  2021.05.20 Kyoto

Su Su Lei Mon，Kotaro Yoshioka，Chunyan Jia，Taiki Kunieda，Yutaro Asami，Kie Yoshida-tanaka，Wenying Piao，Hiroya Kuwahara，Kazutaka Nishina，Tetsuya Nagata，Takanori Yokota. Overhanging duplex oligonucleotide enhances potency and mitigates toxicity intracerebroventricularly. 62nd Annual Meeting of the Japanese Society of Neurology  2021.05.19 Kyoto

Motoki Miura，Fumika Sakaue，Taro Ishiguro，Ryo Iwase，Tatsuhiko Sano，Rintaro Hara，Takeshi Wada，Tetsuya Nagata，Takanori Yokota. TDP-43-specific aptamer rescues ALS phenotype in TDP-43 transgenic mice. 62nd Annual Meeting of the Japanese Society of Neurology  2021.05.19 Kyoto

Miwa Higashi，Michi Okita，Hanako Aoki，Takashi Ishii，Tetsuya Nagata，Taro Ishiguro，Takanori Yokota，Kinya Ishikawa. What are the roles of TGGAA penta-nucleotide repeats as bidirectional transcripts in SCA31?. 62nd Annual Meeting of the Japanese Society of Neurology  2021.05.19 Kyoto

Hanako Aoki，Miwa Higashi，Michi Okita，Takanori Yokota，Kinya Ishikawa. Expression of thymidine kinase 2 gene in human SCA31 cerebellum. 62nd Annual Meeting of the Japanese Society of Neurology  2021.05.19 Kyoto

Ishikawa K,Higashi M,Okita M,Aoki H,Asaka M,Ishiguro T,Sato N,Nagai Y,Yanagihara D,Yokota T. Pathogenesis of spinocerebellar ataxia type31(SCA31). 61st Annual Meeting of the Japanese Society of Neurology 2020.09.02 Okayama

Iwase R,Sanjo N,Ishiguro T,Yokota T. Clinical characteristics and pathophysiology of a rare muscle atrophy in superficial siderosis. 61st Annual Meeting of the Japanese Society of Neurology 2020.08.31 Okayama

Akaza M,Kawabata S,Watanabe T,Miyano Y,Mizuguchi R,Kaminaka S,Iida S,Sasaki T,Adachi Y,Sekihara K,Sumi Y,Okawa A,Yokota . The evaluation of nerve activity using magnetic field measurement and positional information by US. 61st Annual Meeting of the Japanese Society of Neurology 2020.08.31 Okayama

Nishi R,Ohyagi M,Nagata T,Mabuchi Y,Yokota T. DNA/RNA heteroduplex oligonucleotide technology for regulating activated microglia and macrophages. 61st Annual Meeting of the Japanese Society of Neurology 2020.08.31

Yokote H,Toru S,Nishida Y,Hattori T,Sanjo N,Yokota T. Association between serum amyloid A and cortical volume in patients with multiple sclerosis. 61st Annual Meeting of the Japanese Society of Neurology 2020.08.31 Okayama

Aoki H,Higashi M,Okita M,Yokota T,Ishikawa K. Expression of thymidine kinase 2 and mitochondrial proteins in SCA31 human brains. 61st Annual Meeting of the Japanese Society of Neurology 2020.08.31 Okayama

Ohara M,Takagi K,Yoshida K,Maeda Y,Hara R,Sato K,Nagata T,Wada T,Yokota T. Development of antidote for therapeutic oligonucleotides which reduces the acute toxicity. 61st Annual Meeting of the Japanese Society of Neurology 2020.08.31

Jia C,Yoshioka K,Lei Mon S,Tanaka K,Nagata T,Yokota T. Heteroduplex Oligonucleotides technology improves therapeutic index for CNS diseases. 61st Annual Meeting of the Japanese Society of Neurology 2020.08.31

Maruoka H,Hattori T,Orimo S,Yokota T. Graph theoretical analysis of structural brain network of Alzheimer's disease patients. 61st Annual Meeting of the Japanese Society of Neurology 2020.08.31 Okayama

Yoshioka K,Kunieda T,Asami Y,Tanaka K,Piao W,Kuwahara H,Nishina K,Nagata T,Yokota T. Treatment for FAP with overhanging heteroduplex oligonucleotides by transferrin-mediated delivery. 61st Annual Meeting of the Japanese Society of Neurology 2020.08.31 Okayama

Yokota T,Nagata T,Dwyer C,Yoshida K,Yoshioka K,Seth P,Rigo F,Bennett F. Development of BBB-penetrating heteroduplex oligonucleotides(HDO). 61st Annual Meeting of the Japanese Society of Neurology 2020.08.31 Okayama

Sano T,Nagata T,Tanaka K,Ebihara S,Mochizuki H,Hasegawa M,Yokota T. Inhibition of SNCA Propagation by locally injected ASO in wt mice. 61st Annual Meeting of the Japanese Society of Neurology 2020.08.31

Higashi M,Okita M,Sato N,Asaka M,Ishii T,Aoki H,Ishiguro T,Yanagihara D,Yokota T.Ishikawa K. SCA31 transgenic mice show pathologic features similar to human patients. 61st Annual Meeting of the Japanese Society of Neurology 2020.08.31 Okayama

Ohyagi M,Nagata T,Ihara K,Nishi R,Mabuchi Y,Akazawa C,Yokota T. New therapeutics strategy for multiple sclerosis by DNA/RNA heteroduplex oligonucleotide technology. 61st Annual Meeting of the Japanese Society of Neurology 2020.08.31 Okayama

Irioka T,Motomura M,Igarahi S,Takahahi Y,Iwase R,Otani T,Kitanosono H,Shiraihi H,Iizuka T,Yokota T. Calcium channels antibody-associated paraneoplastic disorders other than Lambert-Eaton syndrome. 61st Annual Meeting of the Japanese Society of Neurology 2020.08.31 Okayama

Asami Y,Nagata T,Yoshioka K,Kunieda T,Yoshida-Tanaka K,Yokota T. Efficient gene suppression by DNA/DNA double-stranded oligonucleotide in vivo. 61st Annual Meeting of the Japanese Society of Neurology 2020.08.31

Takanori Yokota. New Stage of DNA/RNA Heteroduplex Oligonucleotide. Asia TIDES:Oligonucleotide & Peptide Therapeutics 2020.02.24 kyoto

Kotaro Yoshioka. Heteroduplex-Oligonucleotides　for　Highly　Efficient　Silencing　of　microRNA　through　a　Novel　intracellular Mechanism. 2019　Oligonucleotides　Meeting 2019.11.16 Munich

Takanori Yokota. Systemically Administered DNA/RNA Heteroduplex Oligonucleotides That Can Efficiently Regulate CNS Genes*. TIDES Europe2019:Oligonucleotide &Peptide Therapeutics 2019.11.13 Amsterdam

Amano A,Sanjo N,Nakakido M,Tsumoto K,Matsubara E,Furukawa F,Nishida Y,Saito T,Saido T,Yokota T,. Quantitative evaluation of Aβ oligomer in mouse brain using dot blot method. 第38回日本認知症学会学術集会 2019.11.07 新宿

Otani Tai, Iwase Ryo, Takahashi Yuko K., Soga Kazumasa, Kim Yangsu, Igarashi Susumu, Kaneko Kimihiko, Takahashi Toshiyuki, Irioka Takashi, Yokota Takanori. MOG抗体陽性中枢神経疾患の多様性(A Variety of Myelin Oligodendrocyte Glycoprotein Antibody Positive Central Nervous System Disorders). 臨床神経学 2019.11.01

Iwase Ryo, Irioka Takashi, Takahashi Yuko K., Igarashi Susumu, Otani Tai, Soga Kazumasa, Yokota Takanori. 血管内リンパ腫(IVL)3症例の臨床および神経放射線学的研究(Clinical and neuroradiological study of 3 patients with intravascular lymphoma(IVL)). 臨床神経学 2019.11.01

Kim Yangsu, Iwase Ryo, Otani Tai, Igarashi Susumu, Soga Kazumasa, Irioka Takashi, Yokota Takanori. 血液透析患者における水痘・帯状疱疹ウイルス脳炎後の帯状疱疹(Varicella-zoster virus encephalitis followed by herpes zoster in hemodialysis patients). 臨床神経学 2019.11.01

Akaza Miho, Kawabata Shigenori, Watanabe Taishi, Hasegawa Yuki, Iida Shintaro, Sasaki Toru, Adachi Yoshiaki, Sekihara Kensuke, Kanouchi Tadashi, Sumi Yuki, Okawa Atsushi, Yokota Takanori. 脊磁計によるC8神経根症の診断(Diagnosis of C8 radiculopathy by magnetospinogram). 臨床神経学 2019.11.01

Hirata Kosei, Hattori Takaaki, Chen Qingmeng, Ohara Masahiro, Kina Satoko, Yokota Takanori. 線条体でのドーパミン枯渇とパーキンソン病患者におけるストライド長の変動との相関(Striatal dopamine depletion correlates with variability of stride length in Parkinson's disease). 臨床神経学 2019.11.01

高橋 直, 宮本 翔平, 三條 伸夫, 横田 隆徳. 第三脳室幅は慢性進行型神経ベーチェット病の高感度マーカーである(Width of the third ventricle is high-sensitive marker for chronic progressive neuro-Behcet's disease). 臨床神経学 2019.11.01

Sanjo Nobuo, Shishido-Hara Yukiko, Nose Yurie, Yokota Takanori. 疾患修飾療法時代の進行性多巣性白質脳症　炎症の制御と免疫システムの制御はPMLの良好な予後と関連している(Progressive multifocal leukoencephalopathy in the era of disease-modifying therapies　A controlled inflammation and a regulatory immune system are associated with better prognosis of PML). 臨床神経学 2019.11.01

Yokota Takanori. トランスレーショナルリサーチ後の時代における運動ニューロン疾患　ALS治療のオリゴヌクレオチド薬(Motor neuron diseases in the era after translational research　Oligonucleotide drug for treatment of ALS). 臨床神経学 2019.11.01

Ishiguro Taro, Yokota Takanori, Ishikawa Kinya, Nagai Yoshitaka, Petrucelli Leonard. ショウジョウバエのSpt4ノックダウンはSCA31関連の伸長UGGAAリピート誘発毒性を抑制する(Spt4 knockdown suppressed SCA31-linked expanded UGGAA repeat-induced toxicity in Drosophila). 臨床神経学 2019.11.01

Irioka Takashi, Motomura Masakatsu, Uchihara Toshiki, Shintaku Hiroshi, Ishikawa Kinya, Igarashi Susumu, Majima Takamasa, Takahashi Yuko K., Iwase Ryo, Otani Tai, Kitanosono Hiroko, Shiraishi Hirokazu, Tsuura Yukio, Yokota Takanori. カルシウムチャネル抗体関連小脳失調症患者の臨床病理学的研究(Clinicopathological study of a patient with calcium channels antibody-associated cerebellar ataxia). 臨床神経学 2019.11.01

Otani Tai, Iwase Ryo, Takahashi Yuko K., Soga Kazumasa, Kim Yangsu, Igarashi Susumu, Kaneko Kimihiko, Takahashi Toshiyuki, Irioka Takashi, Yokota Takanori. MOG抗体陽性中枢神経疾患の多様性(A Variety of Myelin Oligodendrocyte Glycoprotein Antibody Positive Central Nervous System Disorders). 臨床神経学 2019.11.01

Yokota Takanori. トランスレーショナルリサーチ後の時代における運動ニューロン疾患　ALS治療のオリゴヌクレオチド薬(Motor neuron diseases in the era after translational research　Oligonucleotide drug for treatment of ALS). 臨床神経学 2019.11.01

Ishiguro Taro, Yokota Takanori, Ishikawa Kinya, Nagai Yoshitaka, Petrucelli Leonard. ショウジョウバエのSpt4ノックダウンはSCA31関連の伸長UGGAAリピート誘発毒性を抑制する(Spt4 knockdown suppressed SCA31-linked expanded UGGAA repeat-induced toxicity in Drosophila). 臨床神経学 2019.11.01

Irioka Takashi, Motomura Masakatsu, Uchihara Toshiki, Shintaku Hiroshi, Ishikawa Kinya, Igarashi Susumu, Majima Takamasa, Takahashi Yuko K., Iwase Ryo, Otani Tai, Kitanosono Hiroko, Shiraishi Hirokazu, Tsuura Yukio, Yokota Takanori. カルシウムチャネル抗体関連小脳失調症患者の臨床病理学的研究(Clinicopathological study of a patient with calcium channels antibody-associated cerebellar ataxia). 臨床神経学 2019.11.01

Sanjo Nobuo, Shishido-Hara Yukiko, Nose Yurie, Yokota Takanori. 疾患修飾療法時代の進行性多巣性白質脳症　炎症の制御と免疫システムの制御はPMLの良好な予後と関連している(Progressive multifocal leukoencephalopathy in the era of disease-modifying therapies　A controlled inflammation and a regulatory immune system are associated with better prognosis of PML). 臨床神経学 2019.11.01

Iwase Ryo, Irioka Takashi, Takahashi Yuko K., Igarashi Susumu, Otani Tai, Soga Kazumasa, Yokota Takanori. 血管内リンパ腫(IVL)3症例の臨床および神経放射線学的研究(Clinical and neuroradiological study of 3 patients with intravascular lymphoma(IVL)). 臨床神経学 2019.11.01

Kim Yangsu, Iwase Ryo, Otani Tai, Igarashi Susumu, Soga Kazumasa, Irioka Takashi, Yokota Takanori. 血液透析患者における水痘・帯状疱疹ウイルス脳炎後の帯状疱疹(Varicella-zoster virus encephalitis followed by herpes zoster in hemodialysis patients). 臨床神経学 2019.11.01

Akaza Miho, Kawabata Shigenori, Watanabe Taishi, Hasegawa Yuki, Iida Shintaro, Sasaki Toru, Adachi Yoshiaki, Sekihara Kensuke, Kanouchi Tadashi, Sumi Yuki, Okawa Atsushi, Yokota Takanori. 脊磁計によるC8神経根症の診断(Diagnosis of C8 radiculopathy by magnetospinogram). 臨床神経学 2019.11.01

Hirata Kosei, Hattori Takaaki, Chen Qingmeng, Ohara Masahiro, Kina Satoko, Yokota Takanori. 線条体でのドーパミン枯渇とパーキンソン病患者におけるストライド長の変動との相関(Striatal dopamine depletion correlates with variability of stride length in Parkinson's disease). 臨床神経学 2019.11.01

高橋 直, 宮本 翔平, 三條 伸夫, 横田 隆徳. 第三脳室幅は慢性進行型神経ベーチェット病の高感度マーカーである(Width of the third ventricle is high-sensitive marker for chronic progressive neuro-Behcet's disease). 臨床神経学 2019.11.01

Sanjo Nobuo, Shishido-Hara Yukiko, Nose Yurie, Yokota Takanori. 疾患修飾療法時代の進行性多巣性白質脳症　炎症の制御と免疫システムの制御はPMLの良好な予後と関連している(Progressive multifocal leukoencephalopathy in the era of disease-modifying therapies　A controlled inflammation and a regulatory immune system are associated with better prognosis of PML). 臨床神経学 2019.11.01

Yokota Takanori. トランスレーショナルリサーチ後の時代における運動ニューロン疾患　ALS治療のオリゴヌクレオチド薬(Motor neuron diseases in the era after translational research　Oligonucleotide drug for treatment of ALS). 臨床神経学 2019.11.01

Ishiguro Taro, Yokota Takanori, Ishikawa Kinya, Nagai Yoshitaka, Petrucelli Leonard. ショウジョウバエのSpt4ノックダウンはSCA31関連の伸長UGGAAリピート誘発毒性を抑制する(Spt4 knockdown suppressed SCA31-linked expanded UGGAA repeat-induced toxicity in Drosophila). 臨床神経学 2019.11.01

Irioka Takashi, Motomura Masakatsu, Uchihara Toshiki, Shintaku Hiroshi, Ishikawa Kinya, Igarashi Susumu, Majima Takamasa, Takahashi Yuko K., Iwase Ryo, Otani Tai, Kitanosono Hiroko, Shiraishi Hirokazu, Tsuura Yukio, Yokota Takanori. カルシウムチャネル抗体関連小脳失調症患者の臨床病理学的研究(Clinicopathological study of a patient with calcium channels antibody-associated cerebellar ataxia). 臨床神経学 2019.11.01

Otani Tai, Iwase Ryo, Takahashi Yuko K., Soga Kazumasa, Kim Yangsu, Igarashi Susumu, Kaneko Kimihiko, Takahashi Toshiyuki, Irioka Takashi, Yokota Takanori. MOG抗体陽性中枢神経疾患の多様性(A Variety of Myelin Oligodendrocyte Glycoprotein Antibody Positive Central Nervous System Disorders). 臨床神経学 2019.11.01

Iwase Ryo, Irioka Takashi, Takahashi Yuko K., Igarashi Susumu, Otani Tai, Soga Kazumasa, Yokota Takanori. 血管内リンパ腫(IVL)3症例の臨床および神経放射線学的研究(Clinical and neuroradiological study of 3 patients with intravascular lymphoma(IVL)). 臨床神経学 2019.11.01

Kim Yangsu, Iwase Ryo, Otani Tai, Igarashi Susumu, Soga Kazumasa, Irioka Takashi, Yokota Takanori. 血液透析患者における水痘・帯状疱疹ウイルス脳炎後の帯状疱疹(Varicella-zoster virus encephalitis followed by herpes zoster in hemodialysis patients). 臨床神経学 2019.11.01

Akaza Miho, Kawabata Shigenori, Watanabe Taishi, Hasegawa Yuki, Iida Shintaro, Sasaki Toru, Adachi Yoshiaki, Sekihara Kensuke, Kanouchi Tadashi, Sumi Yuki, Okawa Atsushi, Yokota Takanori. 脊磁計によるC8神経根症の診断(Diagnosis of C8 radiculopathy by magnetospinogram). 臨床神経学 2019.11.01

Hirata Kosei, Hattori Takaaki, Chen Qingmeng, Ohara Masahiro, Kina Satoko, Yokota Takanori. 線条体でのドーパミン枯渇とパーキンソン病患者におけるストライド長の変動との相関(Striatal dopamine depletion correlates with variability of stride length in Parkinson's disease). 臨床神経学 2019.11.01

高橋 直, 宮本 翔平, 三條 伸夫, 横田 隆徳. 第三脳室幅は慢性進行型神経ベーチェット病の高感度マーカーである(Width of the third ventricle is high-sensitive marker for chronic progressive neuro-Behcet's disease). 臨床神経学 2019.11.01

Otani Tai, Iwase Ryo, Takahashi Yuko K., Soga Kazumasa, Kim Yangsu, Igarashi Susumu, Kaneko Kimihiko, Takahashi Toshiyuki, Irioka Takashi, Yokota Takanori. MOG抗体陽性中枢神経疾患の多様性(A Variety of Myelin Oligodendrocyte Glycoprotein Antibody Positive Central Nervous System Disorders). 臨床神経学 2019.11.01

Otani Tai, Iwase Ryo, Takahashi Yuko K., Soga Kazumasa, Kim Yangsu, Igarashi Susumu, Kaneko Kimihiko, Takahashi Toshiyuki, Irioka Takashi, Yokota Takanori. MOG抗体陽性中枢神経疾患の多様性(A Variety of Myelin Oligodendrocyte Glycoprotein Antibody Positive Central Nervous System Disorders). 臨床神経学 2019.11.01

Iwase Ryo, Irioka Takashi, Takahashi Yuko K., Igarashi Susumu, Otani Tai, Soga Kazumasa, Yokota Takanori. 血管内リンパ腫(IVL)3症例の臨床および神経放射線学的研究(Clinical and neuroradiological study of 3 patients with intravascular lymphoma(IVL)). 臨床神経学 2019.11.01

Kim Yangsu, Iwase Ryo, Otani Tai, Igarashi Susumu, Soga Kazumasa, Irioka Takashi, Yokota Takanori. 血液透析患者における水痘・帯状疱疹ウイルス脳炎後の帯状疱疹(Varicella-zoster virus encephalitis followed by herpes zoster in hemodialysis patients). 臨床神経学 2019.11.01

Akaza Miho, Kawabata Shigenori, Watanabe Taishi, Hasegawa Yuki, Iida Shintaro, Sasaki Toru, Adachi Yoshiaki, Sekihara Kensuke, Kanouchi Tadashi, Sumi Yuki, Okawa Atsushi, Yokota Takanori. 脊磁計によるC8神経根症の診断(Diagnosis of C8 radiculopathy by magnetospinogram). 臨床神経学 2019.11.01

Hirata Kosei, Hattori Takaaki, Chen Qingmeng, Ohara Masahiro, Kina Satoko, Yokota Takanori. 線条体でのドーパミン枯渇とパーキンソン病患者におけるストライド長の変動との相関(Striatal dopamine depletion correlates with variability of stride length in Parkinson's disease). 臨床神経学 2019.11.01

高橋 直, 宮本 翔平, 三條 伸夫, 横田 隆徳. 第三脳室幅は慢性進行型神経ベーチェット病の高感度マーカーである(Width of the third ventricle is high-sensitive marker for chronic progressive neuro-Behcet's disease). 臨床神経学 2019.11.01

Sanjo Nobuo, Shishido-Hara Yukiko, Nose Yurie, Yokota Takanori. 疾患修飾療法時代の進行性多巣性白質脳症　炎症の制御と免疫システムの制御はPMLの良好な予後と関連している(Progressive multifocal leukoencephalopathy in the era of disease-modifying therapies　A controlled inflammation and a regulatory immune system are associated with better prognosis of PML). 臨床神経学 2019.11.01

Yokota Takanori. トランスレーショナルリサーチ後の時代における運動ニューロン疾患　ALS治療のオリゴヌクレオチド薬(Motor neuron diseases in the era after translational research　Oligonucleotide drug for treatment of ALS). 臨床神経学 2019.11.01

Ishiguro Taro, Yokota Takanori, Ishikawa Kinya, Nagai Yoshitaka, Petrucelli Leonard. ショウジョウバエのSpt4ノックダウンはSCA31関連の伸長UGGAAリピート誘発毒性を抑制する(Spt4 knockdown suppressed SCA31-linked expanded UGGAA repeat-induced toxicity in Drosophila). 臨床神経学 2019.11.01

Irioka Takashi, Motomura Masakatsu, Uchihara Toshiki, Shintaku Hiroshi, Ishikawa Kinya, Igarashi Susumu, Majima Takamasa, Takahashi Yuko K., Iwase Ryo, Otani Tai, Kitanosono Hiroko, Shiraishi Hirokazu, Tsuura Yukio, Yokota Takanori. カルシウムチャネル抗体関連小脳失調症患者の臨床病理学的研究(Clinicopathological study of a patient with calcium channels antibody-associated cerebellar ataxia). 臨床神経学 2019.11.01

Irioka Takashi, Motomura Masakatsu, Uchihara Toshiki, Shintaku Hiroshi, Ishikawa Kinya, Igarashi Susumu, Majima Takamasa, Takahashi Yuko K., Iwase Ryo, Otani Tai, Kitanosono Hiroko, Shiraishi Hirokazu, Tsuura Yukio, Yokota Takanori. カルシウムチャネル抗体関連小脳失調症患者の臨床病理学的研究(Clinicopathological study of a patient with calcium channels antibody-associated cerebellar ataxia). 臨床神経学 2019.11.01

Iwase Ryo, Irioka Takashi, Takahashi Yuko K., Igarashi Susumu, Otani Tai, Soga Kazumasa, Yokota Takanori. 血管内リンパ腫(IVL)3症例の臨床および神経放射線学的研究(Clinical and neuroradiological study of 3 patients with intravascular lymphoma(IVL)). 臨床神経学 2019.11.01

Kim Yangsu, Iwase Ryo, Otani Tai, Igarashi Susumu, Soga Kazumasa, Irioka Takashi, Yokota Takanori. 血液透析患者における水痘・帯状疱疹ウイルス脳炎後の帯状疱疹(Varicella-zoster virus encephalitis followed by herpes zoster in hemodialysis patients). 臨床神経学 2019.11.01

Akaza Miho, Kawabata Shigenori, Watanabe Taishi, Hasegawa Yuki, Iida Shintaro, Sasaki Toru, Adachi Yoshiaki, Sekihara Kensuke, Kanouchi Tadashi, Sumi Yuki, Okawa Atsushi, Yokota Takanori. 脊磁計によるC8神経根症の診断(Diagnosis of C8 radiculopathy by magnetospinogram). 臨床神経学 2019.11.01

Hirata Kosei, Hattori Takaaki, Chen Qingmeng, Ohara Masahiro, Kina Satoko, Yokota Takanori. 線条体でのドーパミン枯渇とパーキンソン病患者におけるストライド長の変動との相関(Striatal dopamine depletion correlates with variability of stride length in Parkinson's disease). 臨床神経学 2019.11.01

高橋 直, 宮本 翔平, 三條 伸夫, 横田 隆徳. 第三脳室幅は慢性進行型神経ベーチェット病の高感度マーカーである(Width of the third ventricle is high-sensitive marker for chronic progressive neuro-Behcet's disease). 臨床神経学 2019.11.01

Sanjo Nobuo, Shishido-Hara Yukiko, Nose Yurie, Yokota Takanori. 疾患修飾療法時代の進行性多巣性白質脳症　炎症の制御と免疫システムの制御はPMLの良好な予後と関連している(Progressive multifocal leukoencephalopathy in the era of disease-modifying therapies　A controlled inflammation and a regulatory immune system are associated with better prognosis of PML). 臨床神経学 2019.11.01

Yokota Takanori. トランスレーショナルリサーチ後の時代における運動ニューロン疾患　ALS治療のオリゴヌクレオチド薬(Motor neuron diseases in the era after translational research　Oligonucleotide drug for treatment of ALS). 臨床神経学 2019.11.01

Ishiguro Taro, Yokota Takanori, Ishikawa Kinya, Nagai Yoshitaka, Petrucelli Leonard. ショウジョウバエのSpt4ノックダウンはSCA31関連の伸長UGGAAリピート誘発毒性を抑制する(Spt4 knockdown suppressed SCA31-linked expanded UGGAA repeat-induced toxicity in Drosophila). 臨床神経学 2019.11.01

Otani Tai, Iwase Ryo, Takahashi Yuko K., Soga Kazumasa, Kim Yangsu, Igarashi Susumu, Kaneko Kimihiko, Takahashi Toshiyuki, Irioka Takashi, Yokota Takanori. MOG抗体陽性中枢神経疾患の多様性(A Variety of Myelin Oligodendrocyte Glycoprotein Antibody Positive Central Nervous System Disorders). 臨床神経学 2019.11.01

Iwase Ryo, Irioka Takashi, Takahashi Yuko K., Igarashi Susumu, Otani Tai, Soga Kazumasa, Yokota Takanori. 血管内リンパ腫(IVL)3症例の臨床および神経放射線学的研究(Clinical and neuroradiological study of 3 patients with intravascular lymphoma(IVL)). 臨床神経学 2019.11.01

Kim Yangsu, Iwase Ryo, Otani Tai, Igarashi Susumu, Soga Kazumasa, Irioka Takashi, Yokota Takanori. 血液透析患者における水痘・帯状疱疹ウイルス脳炎後の帯状疱疹(Varicella-zoster virus encephalitis followed by herpes zoster in hemodialysis patients). 臨床神経学 2019.11.01

Akaza Miho, Kawabata Shigenori, Watanabe Taishi, Hasegawa Yuki, Iida Shintaro, Sasaki Toru, Adachi Yoshiaki, Sekihara Kensuke, Kanouchi Tadashi, Sumi Yuki, Okawa Atsushi, Yokota Takanori. 脊磁計によるC8神経根症の診断(Diagnosis of C8 radiculopathy by magnetospinogram). 臨床神経学 2019.11.01

Hirata Kosei, Hattori Takaaki, Chen Qingmeng, Ohara Masahiro, Kina Satoko, Yokota Takanori. 線条体でのドーパミン枯渇とパーキンソン病患者におけるストライド長の変動との相関(Striatal dopamine depletion correlates with variability of stride length in Parkinson's disease). 臨床神経学 2019.11.01

高橋 直, 宮本 翔平, 三條 伸夫, 横田 隆徳. 第三脳室幅は慢性進行型神経ベーチェット病の高感度マーカーである(Width of the third ventricle is high-sensitive marker for chronic progressive neuro-Behcet's disease). 臨床神経学 2019.11.01

Sanjo Nobuo, Shishido-Hara Yukiko, Nose Yurie, Yokota Takanori. 疾患修飾療法時代の進行性多巣性白質脳症　炎症の制御と免疫システムの制御はPMLの良好な予後と関連している(Progressive multifocal leukoencephalopathy in the era of disease-modifying therapies　A controlled inflammation and a regulatory immune system are associated with better prognosis of PML). 臨床神経学 2019.11.01

Yokota Takanori. トランスレーショナルリサーチ後の時代における運動ニューロン疾患　ALS治療のオリゴヌクレオチド薬(Motor neuron diseases in the era after translational research　Oligonucleotide drug for treatment of ALS). 臨床神経学 2019.11.01

Ishiguro Taro, Yokota Takanori, Ishikawa Kinya, Nagai Yoshitaka, Petrucelli Leonard. ショウジョウバエのSpt4ノックダウンはSCA31関連の伸長UGGAAリピート誘発毒性を抑制する(Spt4 knockdown suppressed SCA31-linked expanded UGGAA repeat-induced toxicity in Drosophila). 臨床神経学 2019.11.01

Irioka Takashi, Motomura Masakatsu, Uchihara Toshiki, Shintaku Hiroshi, Ishikawa Kinya, Igarashi Susumu, Majima Takamasa, Takahashi Yuko K., Iwase Ryo, Otani Tai, Kitanosono Hiroko, Shiraishi Hirokazu, Tsuura Yukio, Yokota Takanori. カルシウムチャネル抗体関連小脳失調症患者の臨床病理学的研究(Clinicopathological study of a patient with calcium channels antibody-associated cerebellar ataxia). 臨床神経学 2019.11.01

Otani Tai, Iwase Ryo, Takahashi Yuko K., Soga Kazumasa, Kim Yangsu, Igarashi Susumu, Kaneko Kimihiko, Takahashi Toshiyuki, Irioka Takashi, Yokota Takanori. MOG抗体陽性中枢神経疾患の多様性(A Variety of Myelin Oligodendrocyte Glycoprotein Antibody Positive Central Nervous System Disorders). 臨床神経学 2019.11.01

Iwase Ryo, Irioka Takashi, Takahashi Yuko K., Igarashi Susumu, Otani Tai, Soga Kazumasa, Yokota Takanori. 血管内リンパ腫(IVL)3症例の臨床および神経放射線学的研究(Clinical and neuroradiological study of 3 patients with intravascular lymphoma(IVL)). 臨床神経学 2019.11.01

Kim Yangsu, Iwase Ryo, Otani Tai, Igarashi Susumu, Soga Kazumasa, Irioka Takashi, Yokota Takanori. 血液透析患者における水痘・帯状疱疹ウイルス脳炎後の帯状疱疹(Varicella-zoster virus encephalitis followed by herpes zoster in hemodialysis patients). 臨床神経学 2019.11.01

Akaza Miho, Kawabata Shigenori, Watanabe Taishi, Hasegawa Yuki, Iida Shintaro, Sasaki Toru, Adachi Yoshiaki, Sekihara Kensuke, Kanouchi Tadashi, Sumi Yuki, Okawa Atsushi, Yokota Takanori. 脊磁計によるC8神経根症の診断(Diagnosis of C8 radiculopathy by magnetospinogram). 臨床神経学 2019.11.01

Hirata Kosei, Hattori Takaaki, Chen Qingmeng, Ohara Masahiro, Kina Satoko, Yokota Takanori. 線条体でのドーパミン枯渇とパーキンソン病患者におけるストライド長の変動との相関(Striatal dopamine depletion correlates with variability of stride length in Parkinson's disease). 臨床神経学 2019.11.01

高橋 直, 宮本 翔平, 三條 伸夫, 横田 隆徳. 第三脳室幅は慢性進行型神経ベーチェット病の高感度マーカーである(Width of the third ventricle is high-sensitive marker for chronic progressive neuro-Behcet's disease). 臨床神経学 2019.11.01

Sanjo Nobuo, Shishido-Hara Yukiko, Nose Yurie, Yokota Takanori. 疾患修飾療法時代の進行性多巣性白質脳症　炎症の制御と免疫システムの制御はPMLの良好な予後と関連している(Progressive multifocal leukoencephalopathy in the era of disease-modifying therapies　A controlled inflammation and a regulatory immune system are associated with better prognosis of PML). 臨床神経学 2019.11.01

Yokota Takanori. トランスレーショナルリサーチ後の時代における運動ニューロン疾患　ALS治療のオリゴヌクレオチド薬(Motor neuron diseases in the era after translational research　Oligonucleotide drug for treatment of ALS). 臨床神経学 2019.11.01

Ishiguro Taro, Yokota Takanori, Ishikawa Kinya, Nagai Yoshitaka, Petrucelli Leonard. ショウジョウバエのSpt4ノックダウンはSCA31関連の伸長UGGAAリピート誘発毒性を抑制する(Spt4 knockdown suppressed SCA31-linked expanded UGGAA repeat-induced toxicity in Drosophila). 臨床神経学 2019.11.01

Irioka Takashi, Motomura Masakatsu, Uchihara Toshiki, Shintaku Hiroshi, Ishikawa Kinya, Igarashi Susumu, Majima Takamasa, Takahashi Yuko K., Iwase Ryo, Otani Tai, Kitanosono Hiroko, Shiraishi Hirokazu, Tsuura Yukio, Yokota Takanori. カルシウムチャネル抗体関連小脳失調症患者の臨床病理学的研究(Clinicopathological study of a patient with calcium channels antibody-associated cerebellar ataxia). 臨床神経学 2019.11.01

Otani Tai, Iwase Ryo, Takahashi Yuko K., Soga Kazumasa, Kim Yangsu, Igarashi Susumu, Kaneko Kimihiko, Takahashi Toshiyuki, Irioka Takashi, Yokota Takanori. MOG抗体陽性中枢神経疾患の多様性(A Variety of Myelin Oligodendrocyte Glycoprotein Antibody Positive Central Nervous System Disorders). 臨床神経学 2019.11.01

Ishiguro Taro, Yokota Takanori, Ishikawa Kinya, Nagai Yoshitaka, Petrucelli Leonard. ショウジョウバエのSpt4ノックダウンはSCA31関連の伸長UGGAAリピート誘発毒性を抑制する(Spt4 knockdown suppressed SCA31-linked expanded UGGAA repeat-induced toxicity in Drosophila). 臨床神経学 2019.11.01

Iwase Ryo, Irioka Takashi, Takahashi Yuko K., Igarashi Susumu, Otani Tai, Soga Kazumasa, Yokota Takanori. 血管内リンパ腫(IVL)3症例の臨床および神経放射線学的研究(Clinical and neuroradiological study of 3 patients with intravascular lymphoma(IVL)). 臨床神経学 2019.11.01

Kim Yangsu, Iwase Ryo, Otani Tai, Igarashi Susumu, Soga Kazumasa, Irioka Takashi, Yokota Takanori. 血液透析患者における水痘・帯状疱疹ウイルス脳炎後の帯状疱疹(Varicella-zoster virus encephalitis followed by herpes zoster in hemodialysis patients). 臨床神経学 2019.11.01

Akaza Miho, Kawabata Shigenori, Watanabe Taishi, Hasegawa Yuki, Iida Shintaro, Sasaki Toru, Adachi Yoshiaki, Sekihara Kensuke, Kanouchi Tadashi, Sumi Yuki, Okawa Atsushi, Yokota Takanori. 脊磁計によるC8神経根症の診断(Diagnosis of C8 radiculopathy by magnetospinogram). 臨床神経学 2019.11.01

Hirata Kosei, Hattori Takaaki, Chen Qingmeng, Ohara Masahiro, Kina Satoko, Yokota Takanori. 線条体でのドーパミン枯渇とパーキンソン病患者におけるストライド長の変動との相関(Striatal dopamine depletion correlates with variability of stride length in Parkinson's disease). 臨床神経学 2019.11.01

高橋 直, 宮本 翔平, 三條 伸夫, 横田 隆徳. 第三脳室幅は慢性進行型神経ベーチェット病の高感度マーカーである(Width of the third ventricle is high-sensitive marker for chronic progressive neuro-Behcet's disease). 臨床神経学 2019.11.01

Sanjo Nobuo, Shishido-Hara Yukiko, Nose Yurie, Yokota Takanori. 疾患修飾療法時代の進行性多巣性白質脳症　炎症の制御と免疫システムの制御はPMLの良好な予後と関連している(Progressive multifocal leukoencephalopathy in the era of disease-modifying therapies　A controlled inflammation and a regulatory immune system are associated with better prognosis of PML). 臨床神経学 2019.11.01

Yokota Takanori. トランスレーショナルリサーチ後の時代における運動ニューロン疾患　ALS治療のオリゴヌクレオチド薬(Motor neuron diseases in the era after translational research　Oligonucleotide drug for treatment of ALS). 臨床神経学 2019.11.01

Irioka Takashi, Motomura Masakatsu, Uchihara Toshiki, Shintaku Hiroshi, Ishikawa Kinya, Igarashi Susumu, Majima Takamasa, Takahashi Yuko K., Iwase Ryo, Otani Tai, Kitanosono Hiroko, Shiraishi Hirokazu, Tsuura Yukio, Yokota Takanori. カルシウムチャネル抗体関連小脳失調症患者の臨床病理学的研究(Clinicopathological study of a patient with calcium channels antibody-associated cerebellar ataxia). 臨床神経学 2019.11.01

Otani Tai, Iwase Ryo, Takahashi Yuko K., Soga Kazumasa, Kim Yangsu, Igarashi Susumu, Kaneko Kimihiko, Takahashi Toshiyuki, Irioka Takashi, Yokota Takanori. MOG抗体陽性中枢神経疾患の多様性(A Variety of Myelin Oligodendrocyte Glycoprotein Antibody Positive Central Nervous System Disorders). 臨床神経学 2019.11.01

Iwase Ryo, Irioka Takashi, Takahashi Yuko K., Igarashi Susumu, Otani Tai, Soga Kazumasa, Yokota Takanori. 血管内リンパ腫(IVL)3症例の臨床および神経放射線学的研究(Clinical and neuroradiological study of 3 patients with intravascular lymphoma(IVL)). 臨床神経学 2019.11.01

Kim Yangsu, Iwase Ryo, Otani Tai, Igarashi Susumu, Soga Kazumasa, Irioka Takashi, Yokota Takanori. 血液透析患者における水痘・帯状疱疹ウイルス脳炎後の帯状疱疹(Varicella-zoster virus encephalitis followed by herpes zoster in hemodialysis patients). 臨床神経学 2019.11.01

Akaza Miho, Kawabata Shigenori, Watanabe Taishi, Hasegawa Yuki, Iida Shintaro, Sasaki Toru, Adachi Yoshiaki, Sekihara Kensuke, Kanouchi Tadashi, Sumi Yuki, Okawa Atsushi, Yokota Takanori. 脊磁計によるC8神経根症の診断(Diagnosis of C8 radiculopathy by magnetospinogram). 臨床神経学 2019.11.01

Hirata Kosei, Hattori Takaaki, Chen Qingmeng, Ohara Masahiro, Kina Satoko, Yokota Takanori. 線条体でのドーパミン枯渇とパーキンソン病患者におけるストライド長の変動との相関(Striatal dopamine depletion correlates with variability of stride length in Parkinson's disease). 臨床神経学 2019.11.01

高橋 直, 宮本 翔平, 三條 伸夫, 横田 隆徳. 第三脳室幅は慢性進行型神経ベーチェット病の高感度マーカーである(Width of the third ventricle is high-sensitive marker for chronic progressive neuro-Behcet's disease). 臨床神経学 2019.11.01

Sanjo Nobuo, Shishido-Hara Yukiko, Nose Yurie, Yokota Takanori. 疾患修飾療法時代の進行性多巣性白質脳症　炎症の制御と免疫システムの制御はPMLの良好な予後と関連している(Progressive multifocal leukoencephalopathy in the era of disease-modifying therapies　A controlled inflammation and a regulatory immune system are associated with better prognosis of PML). 臨床神経学 2019.11.01

Yokota Takanori. トランスレーショナルリサーチ後の時代における運動ニューロン疾患　ALS治療のオリゴヌクレオチド薬(Motor neuron diseases in the era after translational research　Oligonucleotide drug for treatment of ALS). 臨床神経学 2019.11.01

Ishiguro Taro, Yokota Takanori, Ishikawa Kinya, Nagai Yoshitaka, Petrucelli Leonard. ショウジョウバエのSpt4ノックダウンはSCA31関連の伸長UGGAAリピート誘発毒性を抑制する(Spt4 knockdown suppressed SCA31-linked expanded UGGAA repeat-induced toxicity in Drosophila). 臨床神経学 2019.11.01

Irioka Takashi, Motomura Masakatsu, Uchihara Toshiki, Shintaku Hiroshi, Ishikawa Kinya, Igarashi Susumu, Majima Takamasa, Takahashi Yuko K., Iwase Ryo, Otani Tai, Kitanosono Hiroko, Shiraishi Hirokazu, Tsuura Yukio, Yokota Takanori. カルシウムチャネル抗体関連小脳失調症患者の臨床病理学的研究(Clinicopathological study of a patient with calcium channels antibody-associated cerebellar ataxia). 臨床神経学 2019.11.01

Otani Tai, Iwase Ryo, Takahashi Yuko K., Soga Kazumasa, Kim Yangsu, Igarashi Susumu, Kaneko Kimihiko, Takahashi Toshiyuki, Irioka Takashi, Yokota Takanori. MOG抗体陽性中枢神経疾患の多様性(A Variety of Myelin Oligodendrocyte Glycoprotein Antibody Positive Central Nervous System Disorders). 臨床神経学 2019.11.01

Iwase Ryo, Irioka Takashi, Takahashi Yuko K., Igarashi Susumu, Otani Tai, Soga Kazumasa, Yokota Takanori. 血管内リンパ腫(IVL)3症例の臨床および神経放射線学的研究(Clinical and neuroradiological study of 3 patients with intravascular lymphoma(IVL)). 臨床神経学 2019.11.01

Kim Yangsu, Iwase Ryo, Otani Tai, Igarashi Susumu, Soga Kazumasa, Irioka Takashi, Yokota Takanori. 血液透析患者における水痘・帯状疱疹ウイルス脳炎後の帯状疱疹(Varicella-zoster virus encephalitis followed by herpes zoster in hemodialysis patients). 臨床神経学 2019.11.01

Akaza Miho, Kawabata Shigenori, Watanabe Taishi, Hasegawa Yuki, Iida Shintaro, Sasaki Toru, Adachi Yoshiaki, Sekihara Kensuke, Kanouchi Tadashi, Sumi Yuki, Okawa Atsushi, Yokota Takanori. 脊磁計によるC8神経根症の診断(Diagnosis of C8 radiculopathy by magnetospinogram). 臨床神経学 2019.11.01

Hirata Kosei, Hattori Takaaki, Chen Qingmeng, Ohara Masahiro, Kina Satoko, Yokota Takanori. 線条体でのドーパミン枯渇とパーキンソン病患者におけるストライド長の変動との相関(Striatal dopamine depletion correlates with variability of stride length in Parkinson's disease). 臨床神経学 2019.11.01

高橋 直, 宮本 翔平, 三條 伸夫, 横田 隆徳. 第三脳室幅は慢性進行型神経ベーチェット病の高感度マーカーである(Width of the third ventricle is high-sensitive marker for chronic progressive neuro-Behcet's disease). 臨床神経学 2019.11.01

Sanjo Nobuo, Shishido-Hara Yukiko, Nose Yurie, Yokota Takanori. 疾患修飾療法時代の進行性多巣性白質脳症　炎症の制御と免疫システムの制御はPMLの良好な予後と関連している(Progressive multifocal leukoencephalopathy in the era of disease-modifying therapies　A controlled inflammation and a regulatory immune system are associated with better prognosis of PML). 臨床神経学 2019.11.01

Yokota Takanori. トランスレーショナルリサーチ後の時代における運動ニューロン疾患　ALS治療のオリゴヌクレオチド薬(Motor neuron diseases in the era after translational research　Oligonucleotide drug for treatment of ALS). 臨床神経学 2019.11.01

Ishiguro Taro, Yokota Takanori, Ishikawa Kinya, Nagai Yoshitaka, Petrucelli Leonard. ショウジョウバエのSpt4ノックダウンはSCA31関連の伸長UGGAAリピート誘発毒性を抑制する(Spt4 knockdown suppressed SCA31-linked expanded UGGAA repeat-induced toxicity in Drosophila). 臨床神経学 2019.11.01

Irioka Takashi, Motomura Masakatsu, Uchihara Toshiki, Shintaku Hiroshi, Ishikawa Kinya, Igarashi Susumu, Majima Takamasa, Takahashi Yuko K., Iwase Ryo, Otani Tai, Kitanosono Hiroko, Shiraishi Hirokazu, Tsuura Yukio, Yokota Takanori. カルシウムチャネル抗体関連小脳失調症患者の臨床病理学的研究(Clinicopathological study of a patient with calcium channels antibody-associated cerebellar ataxia). 臨床神経学 2019.11.01

Yokota T. BBB-penetrating DNA/RNA heteroduplex oligonucleotide efficiently regulating CNS gene.. Tokyo Medical and Dental University-Taipei Medical University Joint Symposium on Medical Innovation 2019.10.05 Taipei

Taiki Matsubayashi, Miho Akaza, Nobuo Sanjo, Tsuyoshi Hamaguchi, Yuichi Hayashi, Takayoshi Shimohata, Masahito Yamada, Takanori Yokota. Focal sharp waves are specific in the early stage of MM2 cortical form of sCJD . Asian Pacific Prion Symposium 2019 2019.10.03 埼玉

Amano Akiko, Sanjo Nobuo, Nakakido Makoto, Tsumoto Kouhei, Matsubara Etsuro, Furukawa Fumiko, Nishida Yoichiro, Saito Takashi, Saido Takaomi, Yokota Takanori. ドットブロット法を用いたマウス脳におけるAβオリゴマーの定量的評価(Quantitative evaluation of Aβ oligomer in mouse brain using dot blot method). Dementia Japan 2019.10.01

Amano Akiko, Sanjo Nobuo, Nakakido Makoto, Tsumoto Kouhei, Matsubara Etsuro, Furukawa Fumiko, Nishida Yoichiro, Saito Takashi, Saido Takaomi, Yokota Takanori. ドットブロット法を用いたマウス脳におけるAβオリゴマーの定量的評価(Quantitative evaluation of Aβ oligomer in mouse brain using dot blot method). Dementia Japan 2019.10.01

Amano Akiko, Sanjo Nobuo, Nakakido Makoto, Tsumoto Kouhei, Matsubara Etsuro, Furukawa Fumiko, Nishida Yoichiro, Saito Takashi, Saido Takaomi, Yokota Takanori. ドットブロット法を用いたマウス脳におけるAβオリゴマーの定量的評価(Quantitative evaluation of Aβ oligomer in mouse brain using dot blot method). Dementia Japan 2019.10.01

Amano Akiko, Sanjo Nobuo, Nakakido Makoto, Tsumoto Kouhei, Matsubara Etsuro, Furukawa Fumiko, Nishida Yoichiro, Saito Takashi, Saido Takaomi, Yokota Takanori. ドットブロット法を用いたマウス脳におけるAβオリゴマーの定量的評価(Quantitative evaluation of Aβ oligomer in mouse brain using dot blot method). Dementia Japan 2019.10.01

Amano Akiko, Sanjo Nobuo, Nakakido Makoto, Tsumoto Kouhei, Matsubara Etsuro, Furukawa Fumiko, Nishida Yoichiro, Saito Takashi, Saido Takaomi, Yokota Takanori. ドットブロット法を用いたマウス脳におけるAβオリゴマーの定量的評価(Quantitative evaluation of Aβ oligomer in mouse brain using dot blot method). Dementia Japan 2019.10.01

Amano Akiko, Sanjo Nobuo, Nakakido Makoto, Tsumoto Kouhei, Matsubara Etsuro, Furukawa Fumiko, Nishida Yoichiro, Saito Takashi, Saido Takaomi, Yokota Takanori. ドットブロット法を用いたマウス脳におけるAβオリゴマーの定量的評価(Quantitative evaluation of Aβ oligomer in mouse brain using dot blot method). Dementia Japan 2019.10.01

Amano Akiko, Sanjo Nobuo, Nakakido Makoto, Tsumoto Kouhei, Matsubara Etsuro, Furukawa Fumiko, Nishida Yoichiro, Saito Takashi, Saido Takaomi, Yokota Takanori. ドットブロット法を用いたマウス脳におけるAβオリゴマーの定量的評価(Quantitative evaluation of Aβ oligomer in mouse brain using dot blot method). Dementia Japan 2019.10.01

Amano Akiko, Sanjo Nobuo, Nakakido Makoto, Tsumoto Kouhei, Matsubara Etsuro, Furukawa Fumiko, Nishida Yoichiro, Saito Takashi, Saido Takaomi, Yokota Takanori. ドットブロット法を用いたマウス脳におけるAβオリゴマーの定量的評価(Quantitative evaluation of Aβ oligomer in mouse brain using dot blot method). Dementia Japan 2019.10.01

Amano Akiko, Sanjo Nobuo, Nakakido Makoto, Tsumoto Kouhei, Matsubara Etsuro, Furukawa Fumiko, Nishida Yoichiro, Saito Takashi, Saido Takaomi, Yokota Takanori. ドットブロット法を用いたマウス脳におけるAβオリゴマーの定量的評価(Quantitative evaluation of Aβ oligomer in mouse brain using dot blot method). Dementia Japan 2019.10.01

Amano Akiko, Sanjo Nobuo, Nakakido Makoto, Tsumoto Kouhei, Matsubara Etsuro, Furukawa Fumiko, Nishida Yoichiro, Saito Takashi, Saido Takaomi, Yokota Takanori. ドットブロット法を用いたマウス脳におけるAβオリゴマーの定量的評価(Quantitative evaluation of Aβ oligomer in mouse brain using dot blot method). Dementia Japan 2019.10.01

Takaaki Hattori. Neural correlates of compensatory process and impaired working memory in Parkinson’s disease during disease progression. 23rd International Congress of Parkinson's Disease and Movement Disrders 2019.09.25 Nice

天野晶子,三條伸夫,仲木戸誠,津本浩平,松原悦朗,古川迪子,西田陽一郎,斉藤貴志,西道隆臣,横田隆徳. ドットブロット法を用いたマウス脳中アミロイドβオリゴマーの定量法評価. 第7回日本アミロイドーシス学会学術集会 2019.08.30 東京

Ono Daisuke, Shishido-Hara Yukiko, Mizutani Saneyuki, Mori Yoko, Ichinose Keiko, Watanabe Mutsufusa, Tanizawa Tohru, Yokota Takanori, Uchihara Toshiki, Fujigasaki Hiroto. 進行性多巣性白質脳症(PML)における脱髄病変の発症　死後脳MRIと神経病理の比較(Development of demyelinating lesions in progressive multifocal leukoencephalopathy(PML): Comparison of magnetic resonance images and neuropathology of post-mortem brain). NEUROPATHOLOGY 2019.08.01

Ono Daisuke, Shishido-Hara Yukiko, Mizutani Saneyuki, Mori Yoko, Ichinose Keiko, Watanabe Mutsufusa, Tanizawa Tohru, Yokota Takanori, Uchihara Toshiki, Fujigasaki Hiroto. 進行性多巣性白質脳症(PML)における脱髄病変の発症　死後脳MRIと神経病理の比較(Development of demyelinating lesions in progressive multifocal leukoencephalopathy(PML): Comparison of magnetic resonance images and neuropathology of post-mortem brain). NEUROPATHOLOGY 2019.08.01

Ono Daisuke, Shishido-Hara Yukiko, Mizutani Saneyuki, Mori Yoko, Ichinose Keiko, Watanabe Mutsufusa, Tanizawa Tohru, Yokota Takanori, Uchihara Toshiki, Fujigasaki Hiroto. 進行性多巣性白質脳症(PML)における脱髄病変の発症　死後脳MRIと神経病理の比較(Development of demyelinating lesions in progressive multifocal leukoencephalopathy(PML): Comparison of magnetic resonance images and neuropathology of post-mortem brain). NEUROPATHOLOGY 2019.08.01

Ono Daisuke, Shishido-Hara Yukiko, Mizutani Saneyuki, Mori Yoko, Ichinose Keiko, Watanabe Mutsufusa, Tanizawa Tohru, Yokota Takanori, Uchihara Toshiki, Fujigasaki Hiroto. 進行性多巣性白質脳症(PML)における脱髄病変の発症　死後脳MRIと神経病理の比較(Development of demyelinating lesions in progressive multifocal leukoencephalopathy(PML): Comparison of magnetic resonance images and neuropathology of post-mortem brain). NEUROPATHOLOGY 2019.08.01

Ono Daisuke, Shishido-Hara Yukiko, Mizutani Saneyuki, Mori Yoko, Ichinose Keiko, Watanabe Mutsufusa, Tanizawa Tohru, Yokota Takanori, Uchihara Toshiki, Fujigasaki Hiroto. 進行性多巣性白質脳症(PML)における脱髄病変の発症　死後脳MRIと神経病理の比較(Development of demyelinating lesions in progressive multifocal leukoencephalopathy(PML): Comparison of magnetic resonance images and neuropathology of post-mortem brain). NEUROPATHOLOGY 2019.08.01

Ono Daisuke, Shishido-Hara Yukiko, Mizutani Saneyuki, Mori Yoko, Ichinose Keiko, Watanabe Mutsufusa, Tanizawa Tohru, Yokota Takanori, Uchihara Toshiki, Fujigasaki Hiroto. 進行性多巣性白質脳症(PML)における脱髄病変の発症　死後脳MRIと神経病理の比較(Development of demyelinating lesions in progressive multifocal leukoencephalopathy(PML): Comparison of magnetic resonance images and neuropathology of post-mortem brain). NEUROPATHOLOGY 2019.08.01

Ono Daisuke, Shishido-Hara Yukiko, Mizutani Saneyuki, Mori Yoko, Ichinose Keiko, Watanabe Mutsufusa, Tanizawa Tohru, Yokota Takanori, Uchihara Toshiki, Fujigasaki Hiroto. 進行性多巣性白質脳症(PML)における脱髄病変の発症　死後脳MRIと神経病理の比較(Development of demyelinating lesions in progressive multifocal leukoencephalopathy(PML): Comparison of magnetic resonance images and neuropathology of post-mortem brain). NEUROPATHOLOGY 2019.08.01

Ono Daisuke, Shishido-Hara Yukiko, Mizutani Saneyuki, Mori Yoko, Ichinose Keiko, Watanabe Mutsufusa, Tanizawa Tohru, Yokota Takanori, Uchihara Toshiki, Fujigasaki Hiroto. 進行性多巣性白質脳症(PML)における脱髄病変の発症　死後脳MRIと神経病理の比較(Development of demyelinating lesions in progressive multifocal leukoencephalopathy(PML): Comparison of magnetic resonance images and neuropathology of post-mortem brain). NEUROPATHOLOGY 2019.08.01

Ono Daisuke, Shishido-Hara Yukiko, Mizutani Saneyuki, Mori Yoko, Ichinose Keiko, Watanabe Mutsufusa, Tanizawa Tohru, Yokota Takanori, Uchihara Toshiki, Fujigasaki Hiroto. 進行性多巣性白質脳症(PML)における脱髄病変の発症　死後脳MRIと神経病理の比較(Development of demyelinating lesions in progressive multifocal leukoencephalopathy(PML): Comparison of magnetic resonance images and neuropathology of post-mortem brain). NEUROPATHOLOGY 2019.08.01

Ono Daisuke, Shishido-Hara Yukiko, Mizutani Saneyuki, Mori Yoko, Ichinose Keiko, Watanabe Mutsufusa, Tanizawa Tohru, Yokota Takanori, Uchihara Toshiki, Fujigasaki Hiroto. 進行性多巣性白質脳症(PML)における脱髄病変の発症　死後脳MRIと神経病理の比較(Development of demyelinating lesions in progressive multifocal leukoencephalopathy(PML): Comparison of magnetic resonance images and neuropathology of post-mortem brain). NEUROPATHOLOGY 2019.08.01

Amano A,Sanjo N,Nakakido M,Tsumoto K,Matsubara E,Nishida Y,Hattori T,Nagata T,Tomiyama T,Yokota T. Quantitative measurement of amyloid-beta oligomer in mouse brain using dot blot assay. ALZHEIMER'S ASSOCIATION INTERNATIONAL CONFERENCE2019 2019.07.16 LOS ANGELES

Iwase Ryo, Irioka Takashi, Takahashi Yuko K, Igarashi Susumu, Otani Tai, Soga Kazumasa, Yokota Takanori. Clinical and neuroradiological study of 3 patients with intravascular lymphoma(IVL). 第60回日本神経学会学術大会 2019.05.25

Otani Tai, Iwase Ryo, Takahashi Yuko K, Soga Kazumasa, Kim Yangsu, Igarashi Susumu, Kaneko Kimihiko, Takahashi Toshiyuki, Irioka Takashi, Yokota Takanori. A Variety of Myelin Oligodendrocyte Glycoprotein Antibody Positive Central Nervous System Disorders. 第60回日本神経学会学術大会 2019.05.25

Sanjo Nobuo, Shishido-hara Yukiko, Nose Yurie, Yokota Takanori. Progressive multifocal leukoencephalopathy in the era of disease-modifying therapies　A controlled inflammation and a regulatory immune system are associated with better prognosis of PML. 第60回日本神経学会学術大会 2019.05.25

Yokota Takanori. Oligonucleotide drug for treatment of ALS. 第６０回日本神経学会学術大会 2019.05.25

高橋 直, 宮本 翔平, 三條 伸夫, 横田 隆徳. Width of the third ventricle is high-sensitive marker for chronic progressive neuro-Behcet's disease. 第60回日本神経学会学術大会 2019.05.25

Hirata Kosei, Hattori Takaaki, Chen Qingmeng, Ohara Masahiro, Kina Satoko, Yokota Takanori. Striatal dopamine depletion correlates with variability of stride length in Parkinson's disease. 第60回日本神経学会学術大会 2019.05.24

Irioka Takashi, Motomura Masakatsu, Uchihara Toshiki, Shintaku Hiroshi, Ishikawa Kinya, Igarashi Susumu, Majima Takamasa, Takahashi Yuko K, Iwase Ryo, Otani Tai, Kitanosono Hiroko, Shiraishi Hirokazu, Tsuura Yukio, Yokota Takanori. Clinicopathological study of a patient with calcium channels antibody-associated cerebellar ataxia. 第60回日本神経学会学術大会 2019.05.24

Ishiguro Taro, Yokota Takanori, Ishikawa Kinya, Nagai Yoshitaka, Petrucelli Leonard. Spt4 knockdown suppressed SCA31-linked expanded UGGAA repeat-induced toxicity in Drosophila. 第60回日本神経学会学術大会 2019.05.24

Kim Yangsu, Iwase Ryo, Otani Tai, Igarashi Susumu, Soga Kazumasa, Irioka Takashi, Yokota Takanori. Varicella-zoster virus encephalitis followed by herpes zoster in hemodialysis patients. 第60回日本神経学会学術大会 2019.05.24

Igarashi S,Otani T,Soga K,Irioka T,Kuhara T,Ozai K,Yokota T. Peri-insular sign:An MRI finding on acute fulminant hyperammonemia caused by a urea cycle disorder. 第60回日本神経学会学術大会 2019.05.23 大阪

Yoshioka K,Lei Mon S,Jia C,Yamada H,Asami Y,Tanaka K,Wenying P,Kuwahara H,Nishina K,Nagata T,Yokota T. A novel antisense oligonucleotide terapy by overhanging heteroduplex oligonucleotide targeting CNS. 第60回日本神経学会学術大会 2019.05.23 大阪

Yokote H,Amano R,Toru S,Hattori T,Nishida Y,Sanjo N,Yokota T. Brain atrophy is associated with higher serum amyloid A levels in patients with multiple sclerosis. 第60回日本神経学会学術大会 2019.05.23 大阪

Akaza Miho, Kawabata Shigenori, Watanabe Taishi, Hasegawa Yuki, Iida Shintaro, Sasaki Toru, Adachi Yoshiaki, Sekihara Kensuke, Kanouchi Tadashi, Sumi Yuki, Okawa Atsushi, Yokota Takanori. Diagnosis of C8 radiculopathy by magnetospinogram. 第60回日本神経学会学術大会 2019.05.23

New DNA/RNA heteroduplex oligonucleotide technology for regulating functions of lymphocytes in vivo. 第60回日本神経学会学術大会 2019.05.22 大阪

Ishibashi S,Li F,Iwasawa E,Suzuki M,Ichinose K,Yokota T. Upregulation of lipoprotein receptors on brain in the early phase of ischemic stroke in mice. 第60回日本神経学会学術大会 2019.05.22 大阪

Yagi Y, Iida S, Kanouchi T, Kusunoki S, Sobue G, Kaji R, Kuwabara S, Yokota T, Glovenin-I CIDP Study Group. Maintenance treatment with IVIg for CIDP can prevent disease progression. 第60回日本神経学会学術大会 2019.05.22 Osaka

Zeniya S,Kuwahara H,Daizo K,Watari A,Kondo M,Yoshida-Tanaka K,Kaburagi H,Asada K,Nagata T,Nagahama M,Yagi K,Yokota T.. BBB-crossing drug delivery system by modulating tight junction at brain microvascular endothelium. 第６０回日本神経学会学術大会 2019.05.22 大阪

Takahashi YK,Nishida Y,Nose Y,Ishibashi S,Sanjo N,Kanai T,Uzawa A,Oda F,Ozawa Y,Kuwabara S,Yokota T. Calcineurin inhibitors can be safely reduced in most patients with well-controlled myasthenia gravis. American Academy of Neurology(AAN)71st Annual Meeting 2019.05.06 Philadelphia

Hashimoto Satoka, Inaji Motoki, Nariai Tadashi, Kobayashi Daisuke, Sanjo Nobuo, Yokota Takanori, Ishii Kenji, Maehara Taketoshi. 高グレード星細胞腫とtumefactive multiple sclerosisを鑑別するための[11C]Methionine PETの有用性(Usefulness of [11C] Methionine PET in the Differentiation of Tumefactive Multiple Sclerosis from High Grade Astrocytoma). Neurologia medico-chirurgica 2019.05.01

八木洋輔,横田隆徳. Small RNA profiling of cerebrospinal fluid exosomes. 第6回JMACシンポジウム 2019.01.24 東京

Shintaku Hiroshi, Yamaguchi Mari, Toru Syuuta, Kitagawa Masanobu, Hirokawa Katsuiku, Uchihara Toshiki, Yokota Takanori. 3-dimensional surface reconstruction from 2-dimensional images. Application to human autopsied brain(和訳中). 臨床神経学 2018.12.01

Akaza Miho, Akaza Itaru, Kanouchi Tadashi, Sasano Tetsuo, Sumi Yuki, Yokota Takanori. Study for association between glycemic variability and diabetic neuropathy assessed by NCS(和訳中). 臨床神経学 2018.12.01

Ohara Masahiro, Hattori Takaaki, Ishibashi Satoru, Sanjo Nobuo, Yokota Takanori. Progressive supranuclear palsy has idiopathic normal pressure hydrocephalus like MRI features(和訳中). 臨床神経学 2018.12.01

Ichijo Masahiko, Ishibashi Satoru, Miki Kazunori, Sugita Yoichiro, Itaya Sakiko, Amino Takeshi, Kamata Tomoyuki, Yokota Takanori. Predictors of Hemorrhagic Transformation in Patients with MCA occlusion Receiving intravenous rt-PA(和訳中). 臨床神経学 2018.12.01

Uehara Takuya, Choong Chi-jing, Nakamori Masayuki, Nishiyama Kumiko, Hayakawa Hideki, Kasahara Yuuya, Baba Kousuke, Nagata Tetsuya, Yokota Takanori, Tsuda Hiroshi, Obika Satoshi, Mochizuki Hideki. A new antisense oligos targeting alpha-synuclein improves motor function in Parkinson's model mouse(和訳中). 臨床神経学 2018.12.01

Shintaku Hiroshi, Yamaguchi Mari, Toru Syuuta, Kitagawa Masanobu, Hirokawa Katsuiku, Uchihara Toshiki, Yokota Takanori. 2D画像からの3D表面再構成　ヒト剖検脳への適用(3-dimensional surface reconstruction from 2-dimensional images. Application to human autopsied brain). 臨床神経学 2018.12.01

Uehara Takuya, Choong Chi-Jing, Nakamori Masayuki, Nishiyama Kumiko, Hayakawa Hideki, Kasahara Yuuya, Baba Kousuke, Nagata Tetsuya, Yokota Takanori, Tsuda Hiroshi, Obika Satoshi, Mochizuki Hideki. α-synucleinを標的とする新たなアンチセンスオリゴヌクレオチドはパーキンソンモデルマウスの運動機能を改善する(A new antisense oligos targeting alpha-synuclein improves motor function in Parkinson's model mouse). 臨床神経学 2018.12.01

Ishibashi Satoru, Iwasawa Eri, Suzuki Motohiro, Li Fuying, Ichijo Masahiko, Miki Kazunori, Yokota Takanori. S1P1活性化は軟髄膜の側副路発達を増強して脳卒中後のアウトカムを改善する(S1P1 activation enhances leptomeningeal collateral development and improves outcome after stroke). 臨床神経学 2018.12.01

Sanjo Nobuo, Shishido-Hara Yukiko, Nose Yurie, Ono Daisuke, Sekijima Yoshiki, Yokota Takanori. 中枢神経系の炎症性JCウイルス感染時におけるPD-1の保護作用(Protective effect of PD-1 during inflammatory JC virus infection of the central nervous system). 臨床神経学 2018.12.01

Akaza Miho, Akaza Itaru, Kanouchi Tadashi, Sasano Tetsuo, Sumi Yuki, Yokota Takanori. 血糖値変動とNCSで評価した糖尿病性ニューロパチーとの関連性の検討(Study for association between glycemic variability and diabetic neuropathy assessed by NCS). 臨床神経学 2018.12.01

Sanjo Nobuo, Shishido-Hara Yukiko, Nose Yurie, Ono Daisuke, Sekijima Yoshiki, Yokota Takanori. 中枢神経系の炎症性JCウイルス感染時におけるPD-1の保護作用(Protective effect of PD-1 during inflammatory JC virus infection of the central nervous system). 臨床神経学 2018.12.01

Uehara Takuya, Choong Chi-Jing, Nakamori Masayuki, Nishiyama Kumiko, Hayakawa Hideki, Kasahara Yuuya, Baba Kousuke, Nagata Tetsuya, Yokota Takanori, Tsuda Hiroshi, Obika Satoshi, Mochizuki Hideki. α-synucleinを標的とする新たなアンチセンスオリゴヌクレオチドはパーキンソンモデルマウスの運動機能を改善する(A new antisense oligos targeting alpha-synuclein improves motor function in Parkinson's model mouse). 臨床神経学 2018.12.01

Ishibashi Satoru, Iwasawa Eri, Suzuki Motohiro, Li Fuying, Ichijo Masahiko, Miki Kazunori, Yokota Takanori. S1P1活性化は軟髄膜の側副路発達を増強して脳卒中後のアウトカムを改善する(S1P1 activation enhances leptomeningeal collateral development and improves outcome after stroke). 臨床神経学 2018.12.01

Shintaku Hiroshi, Yamaguchi Mari, Toru Syuuta, Kitagawa Masanobu, Hirokawa Katsuiku, Uchihara Toshiki, Yokota Takanori. 2D画像からの3D表面再構成　ヒト剖検脳への適用(3-dimensional surface reconstruction from 2-dimensional images. Application to human autopsied brain). 臨床神経学 2018.12.01

Ichijo Masahiko, Ishibashi Satoru, Miki Kazunori, Sugita Yoichiro, Itaya Sakiko, Amino Takeshi, Kamata Tomoyuki, Yokota Takanori. 静脈内rt-PA投与下のMCA閉塞患者における出血性変化の予測因子(Predictors of Hemorrhagic Transformation in Patients with MCA occlusion Receiving intravenous rt-PA). 臨床神経学 2018.12.01

Ohara Masahiro, Hattori Takaaki, Ishibashi Satoru, Sanjo Nobuo, Yokota Takanori. 進行性核上性麻痺患者は特発性正常圧水頭症様のMRI所見を有する(Progressive supranuclear palsy has idiopathic normal pressure hydrocephalus like MRI features). 臨床神経学 2018.12.01

Akaza Miho, Akaza Itaru, Kanouchi Tadashi, Sasano Tetsuo, Sumi Yuki, Yokota Takanori. 血糖値変動とNCSで評価した糖尿病性ニューロパチーとの関連性の検討(Study for association between glycemic variability and diabetic neuropathy assessed by NCS). 臨床神経学 2018.12.01

Ichijo Masahiko, Ishibashi Satoru, Miki Kazunori, Sugita Yoichiro, Itaya Sakiko, Amino Takeshi, Kamata Tomoyuki, Yokota Takanori. 静脈内rt-PA投与下のMCA閉塞患者における出血性変化の予測因子(Predictors of Hemorrhagic Transformation in Patients with MCA occlusion Receiving intravenous rt-PA). 臨床神経学 2018.12.01

Ohara Masahiro, Hattori Takaaki, Ishibashi Satoru, Sanjo Nobuo, Yokota Takanori. 進行性核上性麻痺患者は特発性正常圧水頭症様のMRI所見を有する(Progressive supranuclear palsy has idiopathic normal pressure hydrocephalus like MRI features). 臨床神経学 2018.12.01

Akaza Miho, Akaza Itaru, Kanouchi Tadashi, Sasano Tetsuo, Sumi Yuki, Yokota Takanori. 血糖値変動とNCSで評価した糖尿病性ニューロパチーとの関連性の検討(Study for association between glycemic variability and diabetic neuropathy assessed by NCS). 臨床神経学 2018.12.01

Sanjo Nobuo, Shishido-Hara Yukiko, Nose Yurie, Ono Daisuke, Sekijima Yoshiki, Yokota Takanori. 中枢神経系の炎症性JCウイルス感染時におけるPD-1の保護作用(Protective effect of PD-1 during inflammatory JC virus infection of the central nervous system). 臨床神経学 2018.12.01

Uehara Takuya, Choong Chi-Jing, Nakamori Masayuki, Nishiyama Kumiko, Hayakawa Hideki, Kasahara Yuuya, Baba Kousuke, Nagata Tetsuya, Yokota Takanori, Tsuda Hiroshi, Obika Satoshi, Mochizuki Hideki. α-synucleinを標的とする新たなアンチセンスオリゴヌクレオチドはパーキンソンモデルマウスの運動機能を改善する(A new antisense oligos targeting alpha-synuclein improves motor function in Parkinson's model mouse). 臨床神経学 2018.12.01

Ishibashi Satoru, Iwasawa Eri, Suzuki Motohiro, Li Fuying, Ichijo Masahiko, Miki Kazunori, Yokota Takanori. S1P1活性化は軟髄膜の側副路発達を増強して脳卒中後のアウトカムを改善する(S1P1 activation enhances leptomeningeal collateral development and improves outcome after stroke). 臨床神経学 2018.12.01

Shintaku Hiroshi, Yamaguchi Mari, Toru Syuuta, Kitagawa Masanobu, Hirokawa Katsuiku, Uchihara Toshiki, Yokota Takanori. 2D画像からの3D表面再構成　ヒト剖検脳への適用(3-dimensional surface reconstruction from 2-dimensional images. Application to human autopsied brain). 臨床神経学 2018.12.01

Ichijo Masahiko, Ishibashi Satoru, Miki Kazunori, Sugita Yoichiro, Itaya Sakiko, Amino Takeshi, Kamata Tomoyuki, Yokota Takanori. 静脈内rt-PA投与下のMCA閉塞患者における出血性変化の予測因子(Predictors of Hemorrhagic Transformation in Patients with MCA occlusion Receiving intravenous rt-PA). 臨床神経学 2018.12.01

Ohara Masahiro, Hattori Takaaki, Ishibashi Satoru, Sanjo Nobuo, Yokota Takanori. 進行性核上性麻痺患者は特発性正常圧水頭症様のMRI所見を有する(Progressive supranuclear palsy has idiopathic normal pressure hydrocephalus like MRI features). 臨床神経学 2018.12.01

Shintaku Hiroshi, Yamaguchi Mari, Toru Syuuta, Kitagawa Masanobu, Hirokawa Katsuiku, Uchihara Toshiki, Yokota Takanori. 2D画像からの3D表面再構成　ヒト剖検脳への適用(3-dimensional surface reconstruction from 2-dimensional images. Application to human autopsied brain). 臨床神経学 2018.12.01

Shintaku Hiroshi, Yamaguchi Mari, Toru Syuuta, Kitagawa Masanobu, Hirokawa Katsuiku, Uchihara Toshiki, Yokota Takanori. 2D画像からの3D表面再構成　ヒト剖検脳への適用(3-dimensional surface reconstruction from 2-dimensional images. Application to human autopsied brain). 臨床神経学 2018.12.01

Shintaku Hiroshi, Yamaguchi Mari, Toru Syuuta, Kitagawa Masanobu, Hirokawa Katsuiku, Uchihara Toshiki, Yokota Takanori. 2D画像からの3D表面再構成　ヒト剖検脳への適用(3-dimensional surface reconstruction from 2-dimensional images. Application to human autopsied brain). 臨床神経学 2018.12.01

Ichijo Masahiko, Ishibashi Satoru, Miki Kazunori, Sugita Yoichiro, Itaya Sakiko, Amino Takeshi, Kamata Tomoyuki, Yokota Takanori. 静脈内rt-PA投与下のMCA閉塞患者における出血性変化の予測因子(Predictors of Hemorrhagic Transformation in Patients with MCA occlusion Receiving intravenous rt-PA). 臨床神経学 2018.12.01

Ohara Masahiro, Hattori Takaaki, Ishibashi Satoru, Sanjo Nobuo, Yokota Takanori. 進行性核上性麻痺患者は特発性正常圧水頭症様のMRI所見を有する(Progressive supranuclear palsy has idiopathic normal pressure hydrocephalus like MRI features). 臨床神経学 2018.12.01

Akaza Miho, Akaza Itaru, Kanouchi Tadashi, Sasano Tetsuo, Sumi Yuki, Yokota Takanori. 血糖値変動とNCSで評価した糖尿病性ニューロパチーとの関連性の検討(Study for association between glycemic variability and diabetic neuropathy assessed by NCS). 臨床神経学 2018.12.01

Sanjo Nobuo, Shishido-Hara Yukiko, Nose Yurie, Ono Daisuke, Sekijima Yoshiki, Yokota Takanori. 中枢神経系の炎症性JCウイルス感染時におけるPD-1の保護作用(Protective effect of PD-1 during inflammatory JC virus infection of the central nervous system). 臨床神経学 2018.12.01

Uehara Takuya, Choong Chi-Jing, Nakamori Masayuki, Nishiyama Kumiko, Hayakawa Hideki, Kasahara Yuuya, Baba Kousuke, Nagata Tetsuya, Yokota Takanori, Tsuda Hiroshi, Obika Satoshi, Mochizuki Hideki. α-synucleinを標的とする新たなアンチセンスオリゴヌクレオチドはパーキンソンモデルマウスの運動機能を改善する(A new antisense oligos targeting alpha-synuclein improves motor function in Parkinson's model mouse). 臨床神経学 2018.12.01

Ishibashi Satoru, Iwasawa Eri, Suzuki Motohiro, Li Fuying, Ichijo Masahiko, Miki Kazunori, Yokota Takanori. S1P1活性化は軟髄膜の側副路発達を増強して脳卒中後のアウトカムを改善する(S1P1 activation enhances leptomeningeal collateral development and improves outcome after stroke). 臨床神経学 2018.12.01

Ishibashi Satoru, Iwasawa Eri, Suzuki Motohiro, Li Fuying, Ichijo Masahiko, Miki Kazunori, Yokota Takanori. S1P1活性化は軟髄膜の側副路発達を増強して脳卒中後のアウトカムを改善する(S1P1 activation enhances leptomeningeal collateral development and improves outcome after stroke). 臨床神経学 2018.12.01

Ichijo Masahiko, Ishibashi Satoru, Miki Kazunori, Sugita Yoichiro, Itaya Sakiko, Amino Takeshi, Kamata Tomoyuki, Yokota Takanori. 静脈内rt-PA投与下のMCA閉塞患者における出血性変化の予測因子(Predictors of Hemorrhagic Transformation in Patients with MCA occlusion Receiving intravenous rt-PA). 臨床神経学 2018.12.01

Ohara Masahiro, Hattori Takaaki, Ishibashi Satoru, Sanjo Nobuo, Yokota Takanori. 進行性核上性麻痺患者は特発性正常圧水頭症様のMRI所見を有する(Progressive supranuclear palsy has idiopathic normal pressure hydrocephalus like MRI features). 臨床神経学 2018.12.01

Akaza Miho, Akaza Itaru, Kanouchi Tadashi, Sasano Tetsuo, Sumi Yuki, Yokota Takanori. 血糖値変動とNCSで評価した糖尿病性ニューロパチーとの関連性の検討(Study for association between glycemic variability and diabetic neuropathy assessed by NCS). 臨床神経学 2018.12.01

Sanjo Nobuo, Shishido-Hara Yukiko, Nose Yurie, Ono Daisuke, Sekijima Yoshiki, Yokota Takanori. 中枢神経系の炎症性JCウイルス感染時におけるPD-1の保護作用(Protective effect of PD-1 during inflammatory JC virus infection of the central nervous system). 臨床神経学 2018.12.01

Uehara Takuya, Choong Chi-Jing, Nakamori Masayuki, Nishiyama Kumiko, Hayakawa Hideki, Kasahara Yuuya, Baba Kousuke, Nagata Tetsuya, Yokota Takanori, Tsuda Hiroshi, Obika Satoshi, Mochizuki Hideki. α-synucleinを標的とする新たなアンチセンスオリゴヌクレオチドはパーキンソンモデルマウスの運動機能を改善する(A new antisense oligos targeting alpha-synuclein improves motor function in Parkinson's model mouse). 臨床神経学 2018.12.01

Ichijo Masahiko, Ishibashi Satoru, Miki Kazunori, Sugita Yoichiro, Itaya Sakiko, Amino Takeshi, Kamata Tomoyuki, Yokota Takanori. 静脈内rt-PA投与下のMCA閉塞患者における出血性変化の予測因子(Predictors of Hemorrhagic Transformation in Patients with MCA occlusion Receiving intravenous rt-PA). 臨床神経学 2018.12.01

Sanjo Nobuo, Shishido-Hara Yukiko, Nose Yurie, Ono Daisuke, Sekijima Yoshiki, Yokota Takanori. 中枢神経系の炎症性JCウイルス感染時におけるPD-1の保護作用(Protective effect of PD-1 during inflammatory JC virus infection of the central nervous system). 臨床神経学 2018.12.01

Uehara Takuya, Choong Chi-Jing, Nakamori Masayuki, Nishiyama Kumiko, Hayakawa Hideki, Kasahara Yuuya, Baba Kousuke, Nagata Tetsuya, Yokota Takanori, Tsuda Hiroshi, Obika Satoshi, Mochizuki Hideki. α-synucleinを標的とする新たなアンチセンスオリゴヌクレオチドはパーキンソンモデルマウスの運動機能を改善する(A new antisense oligos targeting alpha-synuclein improves motor function in Parkinson's model mouse). 臨床神経学 2018.12.01

Ishibashi Satoru, Iwasawa Eri, Suzuki Motohiro, Li Fuying, Ichijo Masahiko, Miki Kazunori, Yokota Takanori. S1P1活性化は軟髄膜の側副路発達を増強して脳卒中後のアウトカムを改善する(S1P1 activation enhances leptomeningeal collateral development and improves outcome after stroke). 臨床神経学 2018.12.01

Shintaku Hiroshi, Yamaguchi Mari, Toru Syuuta, Kitagawa Masanobu, Hirokawa Katsuiku, Uchihara Toshiki, Yokota Takanori. 2D画像からの3D表面再構成　ヒト剖検脳への適用(3-dimensional surface reconstruction from 2-dimensional images. Application to human autopsied brain). 臨床神経学 2018.12.01

Akaza Miho, Akaza Itaru, Kanouchi Tadashi, Sasano Tetsuo, Sumi Yuki, Yokota Takanori. 血糖値変動とNCSで評価した糖尿病性ニューロパチーとの関連性の検討(Study for association between glycemic variability and diabetic neuropathy assessed by NCS). 臨床神経学 2018.12.01

Ohara Masahiro, Hattori Takaaki, Ishibashi Satoru, Sanjo Nobuo, Yokota Takanori. 進行性核上性麻痺患者は特発性正常圧水頭症様のMRI所見を有する(Progressive supranuclear palsy has idiopathic normal pressure hydrocephalus like MRI features). 臨床神経学 2018.12.01

Shintaku Hiroshi, Yamaguchi Mari, Toru Syuuta, Kitagawa Masanobu, Hirokawa Katsuiku, Uchihara Toshiki, Yokota Takanori. 2D画像からの3D表面再構成　ヒト剖検脳への適用(3-dimensional surface reconstruction from 2-dimensional images. Application to human autopsied brain). 臨床神経学 2018.12.01

Ichijo Masahiko, Ishibashi Satoru, Miki Kazunori, Sugita Yoichiro, Itaya Sakiko, Amino Takeshi, Kamata Tomoyuki, Yokota Takanori. 静脈内rt-PA投与下のMCA閉塞患者における出血性変化の予測因子(Predictors of Hemorrhagic Transformation in Patients with MCA occlusion Receiving intravenous rt-PA). 臨床神経学 2018.12.01

Ohara Masahiro, Hattori Takaaki, Ishibashi Satoru, Sanjo Nobuo, Yokota Takanori. 進行性核上性麻痺患者は特発性正常圧水頭症様のMRI所見を有する(Progressive supranuclear palsy has idiopathic normal pressure hydrocephalus like MRI features). 臨床神経学 2018.12.01

Akaza Miho, Akaza Itaru, Kanouchi Tadashi, Sasano Tetsuo, Sumi Yuki, Yokota Takanori. 血糖値変動とNCSで評価した糖尿病性ニューロパチーとの関連性の検討(Study for association between glycemic variability and diabetic neuropathy assessed by NCS). 臨床神経学 2018.12.01

Sanjo Nobuo, Shishido-Hara Yukiko, Nose Yurie, Ono Daisuke, Sekijima Yoshiki, Yokota Takanori. 中枢神経系の炎症性JCウイルス感染時におけるPD-1の保護作用(Protective effect of PD-1 during inflammatory JC virus infection of the central nervous system). 臨床神経学 2018.12.01

Uehara Takuya, Choong Chi-Jing, Nakamori Masayuki, Nishiyama Kumiko, Hayakawa Hideki, Kasahara Yuuya, Baba Kousuke, Nagata Tetsuya, Yokota Takanori, Tsuda Hiroshi, Obika Satoshi, Mochizuki Hideki. α-synucleinを標的とする新たなアンチセンスオリゴヌクレオチドはパーキンソンモデルマウスの運動機能を改善する(A new antisense oligos targeting alpha-synuclein improves motor function in Parkinson's model mouse). 臨床神経学 2018.12.01

Ishibashi Satoru, Iwasawa Eri, Suzuki Motohiro, Li Fuying, Ichijo Masahiko, Miki Kazunori, Yokota Takanori. S1P1活性化は軟髄膜の側副路発達を増強して脳卒中後のアウトカムを改善する(S1P1 activation enhances leptomeningeal collateral development and improves outcome after stroke). 臨床神経学 2018.12.01

Shintaku Hiroshi, Yamaguchi Mari, Toru Syuuta, Kitagawa Masanobu, Hirokawa Katsuiku, Uchihara Toshiki, Yokota Takanori. 2D画像からの3D表面再構成　ヒト剖検脳への適用(3-dimensional surface reconstruction from 2-dimensional images. Application to human autopsied brain). 臨床神経学 2018.12.01

Ohara Masahiro, Hattori Takaaki, Ishibashi Satoru, Sanjo Nobuo, Yokota Takanori. 進行性核上性麻痺患者は特発性正常圧水頭症様のMRI所見を有する(Progressive supranuclear palsy has idiopathic normal pressure hydrocephalus like MRI features). 臨床神経学 2018.12.01

Ichijo Masahiko, Ishibashi Satoru, Miki Kazunori, Sugita Yoichiro, Itaya Sakiko, Amino Takeshi, Kamata Tomoyuki, Yokota Takanori. 静脈内rt-PA投与下のMCA閉塞患者における出血性変化の予測因子(Predictors of Hemorrhagic Transformation in Patients with MCA occlusion Receiving intravenous rt-PA). 臨床神経学 2018.12.01

Akaza Miho, Akaza Itaru, Kanouchi Tadashi, Sasano Tetsuo, Sumi Yuki, Yokota Takanori. 血糖値変動とNCSで評価した糖尿病性ニューロパチーとの関連性の検討(Study for association between glycemic variability and diabetic neuropathy assessed by NCS). 臨床神経学 2018.12.01

Sanjo Nobuo, Shishido-Hara Yukiko, Nose Yurie, Ono Daisuke, Sekijima Yoshiki, Yokota Takanori. 中枢神経系の炎症性JCウイルス感染時におけるPD-1の保護作用(Protective effect of PD-1 during inflammatory JC virus infection of the central nervous system). 臨床神経学 2018.12.01

Uehara Takuya, Choong Chi-Jing, Nakamori Masayuki, Nishiyama Kumiko, Hayakawa Hideki, Kasahara Yuuya, Baba Kousuke, Nagata Tetsuya, Yokota Takanori, Tsuda Hiroshi, Obika Satoshi, Mochizuki Hideki. α-synucleinを標的とする新たなアンチセンスオリゴヌクレオチドはパーキンソンモデルマウスの運動機能を改善する(A new antisense oligos targeting alpha-synuclein improves motor function in Parkinson's model mouse). 臨床神経学 2018.12.01

Ishibashi Satoru, Iwasawa Eri, Suzuki Motohiro, Li Fuying, Ichijo Masahiko, Miki Kazunori, Yokota Takanori. S1P1活性化は軟髄膜の側副路発達を増強して脳卒中後のアウトカムを改善する(S1P1 activation enhances leptomeningeal collateral development and improves outcome after stroke). 臨床神経学 2018.12.01

Shintaku Hiroshi, Yamaguchi Mari, Toru Syuuta, Kitagawa Masanobu, Hirokawa Katsuiku, Uchihara Toshiki, Yokota Takanori. 2D画像からの3D表面再構成　ヒト剖検脳への適用(3-dimensional surface reconstruction from 2-dimensional images. Application to human autopsied brain). 臨床神経学 2018.12.01

Ohara Masahiro, Hattori Takaaki, Ishibashi Satoru, Sanjo Nobuo, Yokota Takanori. 進行性核上性麻痺患者は特発性正常圧水頭症様のMRI所見を有する(Progressive supranuclear palsy has idiopathic normal pressure hydrocephalus like MRI features). 臨床神経学 2018.12.01

Ichijo Masahiko, Ishibashi Satoru, Miki Kazunori, Sugita Yoichiro, Itaya Sakiko, Amino Takeshi, Kamata Tomoyuki, Yokota Takanori. 静脈内rt-PA投与下のMCA閉塞患者における出血性変化の予測因子(Predictors of Hemorrhagic Transformation in Patients with MCA occlusion Receiving intravenous rt-PA). 臨床神経学 2018.12.01

Akaza Miho, Akaza Itaru, Kanouchi Tadashi, Sasano Tetsuo, Sumi Yuki, Yokota Takanori. 血糖値変動とNCSで評価した糖尿病性ニューロパチーとの関連性の検討(Study for association between glycemic variability and diabetic neuropathy assessed by NCS). 臨床神経学 2018.12.01

Sanjo Nobuo, Shishido-Hara Yukiko, Nose Yurie, Ono Daisuke, Sekijima Yoshiki, Yokota Takanori. 中枢神経系の炎症性JCウイルス感染時におけるPD-1の保護作用(Protective effect of PD-1 during inflammatory JC virus infection of the central nervous system). 臨床神経学 2018.12.01

Uehara Takuya, Choong Chi-Jing, Nakamori Masayuki, Nishiyama Kumiko, Hayakawa Hideki, Kasahara Yuuya, Baba Kousuke, Nagata Tetsuya, Yokota Takanori, Tsuda Hiroshi, Obika Satoshi, Mochizuki Hideki. α-synucleinを標的とする新たなアンチセンスオリゴヌクレオチドはパーキンソンモデルマウスの運動機能を改善する(A new antisense oligos targeting alpha-synuclein improves motor function in Parkinson's model mouse). 臨床神経学 2018.12.01

Ishibashi Satoru, Iwasawa Eri, Suzuki Motohiro, Li Fuying, Ichijo Masahiko, Miki Kazunori, Yokota Takanori. S1P1活性化は軟髄膜の側副路発達を増強して脳卒中後のアウトカムを改善する(S1P1 activation enhances leptomeningeal collateral development and improves outcome after stroke). 臨床神経学 2018.12.01

Shintaku Hiroshi, Yamaguchi Mari, Toru Syuuta, Kitagawa Masanobu, Hirokawa Katsuiku, Uchihara Toshiki, Yokota Takanori. 2D画像からの3D表面再構成　ヒト剖検脳への適用(3-dimensional surface reconstruction from 2-dimensional images. Application to human autopsied brain). 臨床神経学 2018.12.01

Ichijo Masahiko, Ishibashi Satoru, Miki Kazunori, Sugita Yoichiro, Itaya Sakiko, Amino Takeshi, Kamata Tomoyuki, Yokota Takanori. 静脈内rt-PA投与下のMCA閉塞患者における出血性変化の予測因子(Predictors of Hemorrhagic Transformation in Patients with MCA occlusion Receiving intravenous rt-PA). 臨床神経学 2018.12.01

Ohara Masahiro, Hattori Takaaki, Ishibashi Satoru, Sanjo Nobuo, Yokota Takanori. 進行性核上性麻痺患者は特発性正常圧水頭症様のMRI所見を有する(Progressive supranuclear palsy has idiopathic normal pressure hydrocephalus like MRI features). 臨床神経学 2018.12.01

Akaza Miho, Akaza Itaru, Kanouchi Tadashi, Sasano Tetsuo, Sumi Yuki, Yokota Takanori. 血糖値変動とNCSで評価した糖尿病性ニューロパチーとの関連性の検討(Study for association between glycemic variability and diabetic neuropathy assessed by NCS). 臨床神経学 2018.12.01

Sanjo Nobuo, Shishido-Hara Yukiko, Nose Yurie, Ono Daisuke, Sekijima Yoshiki, Yokota Takanori. 中枢神経系の炎症性JCウイルス感染時におけるPD-1の保護作用(Protective effect of PD-1 during inflammatory JC virus infection of the central nervous system). 臨床神経学 2018.12.01

Uehara Takuya, Choong Chi-Jing, Nakamori Masayuki, Nishiyama Kumiko, Hayakawa Hideki, Kasahara Yuuya, Baba Kousuke, Nagata Tetsuya, Yokota Takanori, Tsuda Hiroshi, Obika Satoshi, Mochizuki Hideki. α-synucleinを標的とする新たなアンチセンスオリゴヌクレオチドはパーキンソンモデルマウスの運動機能を改善する(A new antisense oligos targeting alpha-synuclein improves motor function in Parkinson's model mouse). 臨床神経学 2018.12.01

Ishibashi Satoru, Iwasawa Eri, Suzuki Motohiro, Li Fuying, Ichijo Masahiko, Miki Kazunori, Yokota Takanori. S1P1活性化は軟髄膜の側副路発達を増強して脳卒中後のアウトカムを改善する(S1P1 activation enhances leptomeningeal collateral development and improves outcome after stroke). 臨床神経学 2018.12.01

Zen Kobayashi, Miho Yoshioka, Keisuke Inoue, Mayumi Watanabe, Kaori Kato, Kazunori Toyoda, Yoshiyuki Numasawa, Shoichiro Ishihara, Hiroyuki Tomimitsu, Shuzo Shintani.. Serial changes in Trail Making Test score after mild ischemic stroke. . The 20th Congress of the International Association of Rural Health and Medicine 2018.10.11 Tokyo

Keisuke Inoue, Yoshiyuki Numasawa, Satoshi Sutou, Masaki Hakomori, Kazunori Toyoda, Hiroyuki Tomimitsu. . The combination of Berg Balance Scale and Moss Attention Rating Scale for assessment of walking independence in acute ischemic stroke . . The 20th Congress of the International Association of Rural Health and Medicine 2018.10.11 Tokyo

Takanori Yokota. Glycemic Control Boosts Glucosylated Nanocarrier Crossing the BBB into the Brain. The Oligo Meeting 2018 2018.10.03 Seatle

Kotaro Yoshioka, Taiki Kunieda, Yutaro Asami, Kie Tanaka, Wenying Piao, Hiroya Kuwahara, Kazutaka Nishina, Shingo Ito, Tetsuya Nagata, Takanori Yokota. Overhanging heteroduplex oligonucleotides enable enhanced gene silencing by efficient delivery associated with transferrin. The 2018　Oligo Meeting, 14th Annual Meeting of the Oligonucleotide Therapeutics Society 2018.10.01 USA

Satoshi Zeniya,Hiroya Kuwahara, Kaiichi Daizo, Akihiro Watari, Masuo Kondoh, Kie Yoshida-Tanaka,Hidetoshi Kaburagi, Ken Asada, Tetsuya Nagata, Masahiro Nagahama, Kiyohito Yagi, Takanori Yokota. Angubindin-1 for an efficient in vivo delivery of antisense oligonucleotide across the blood-brain barrier into brain. The 2018　Oligo Meeting, 14th Annual Meeting of the Oligonucleotide Therapeutics Society 2018.10.01 USA

Hiroya Kuwahara, Yasutaka Anraku, Kazunori Kataoka, Takanori Yokota. An efficient drug delivery system across the BBB by utilizing glycemic control. 第41回日本神経科学大会 2018.07.28 神戸

Akiko Amano, Nobuo Sanjo,Makoto Nakakido,Kouhei Tsumoto,Etsuro Matsubara,Fumiko Furukawa,Tetsuya Nagata,Yoichiro Nishida,Hiroya Kuwahara,kosei Hirata,Hiroyuki Maruoka,Takanori Yokota. Dot Blot Assay For Quantitative Measurement of Amyloid-Beta Oligomer. AAIC 2018 2018.07.22 USA

Nobuo Sanjo, Hiroya Kuwahara, Tetsuya Nagata, Yoichiro Nishida, Akiko Amano,Fumiko Furukawa, Kousei Hirata, Hiroyuki Maruoka, Makoto Nakakido, Tsumoto Kohei, Yasutaka Anraku, Kazunori Kataoka, Ichio Aoki, Etsuro Matsubara,Takami Tomiyama, Takanori Yokota. Morecular Imaging And Treatment of Alzheimer's Disease By Developing Amyloid-β oligomer Antibodies That Cross The Blood-Brain Barrier. AAIC 2018 2018.07.22 USA

Takanori Yokota. Glycemic control enables glucosylated nanocarrier crossing the BBB into the brain. 日本核酸医薬学会　第4回年会 2018.07.11 福岡

Su Su Lei Mon,Kotaro Yoshioka, Taiki Kunieda, Yutaro Asami, Wenying Piao, Kie Tanaka, Kazutaka Nishina, Tetsuya Nagata, Takanori Yokota . A novel structure of double-stranded heteroduplex oligonucleotides for intracerebroventricular application. 日本核酸医薬学会　第4回年会 2018.07.10 福岡

Takanori Yokota,Hiroya Kuwahara, Takahiro Shimoura, Jindong Song,Kie Yoshida-Tanaka, Tadahaya Mizuno, Tatsuki Mochizuki, Kazutaka Nishina, Tetsuya Nagata,Hiroyuki Kusuhara,　. Modulation of blood-brain barrier function by a heteroduplex oligonucleotide in vivo. Keystone Symposia 2018.06.20 USA

Ishibashi Satoru, Iwasawa Eri, Suzuki Motohiro, Li Fuying, Ichijo Masahiko, Miki Kazunori, Yokota Takanori. S1P1 activation enhances leptomeningeal collateral development and improves outcome after stroke(和訳中). 第59回日本神経学会学術大会 2018.05.26

横田隆徳. Development of blood-brain barrier-crossing amyloid-beta oligomer antibody.　. 第59回日本神経学会学術大会 2018.05.25 北海道

Hiroya Kuwahara、Takanori Yokota. BBB-crossing delivery mechanism of glucosylated nanocarrier by glycemic control. 第59回日本神経学会学術大会 2018.05.25 札幌

Su Su Lei Mon,Kotaro Yoshioka, Taiki Kunieda, Yutaro Asami, Wenying Piao, Kie Tanaka, Kazutaka Nishina, Tetsuya Nagata, Takanori Yokota. A novel structure of duplex antisense oligonucleotides improves potency via intraventricular route. 第59回日本神経学会学術大会 2018.05.24 札幌

Sanjo Nobuo, Shishido-hara Yukiko, Nose Yurie, Ono Daisuke, Sekijima Yoshiki, Yokota Takanori. Protective effect of PD-1 during inflammatory JC virus infection of the central nervous system(和訳中). 第59回日本神経学会学術大会 2018.05.24 札幌

Kotaro Yoshioka, Takanori Yokota. A new class of double-stranded oligonucleotide enhances in vivo potency of microRNA silencing. 第59回日本神経学会学術大会 2018.05.23 札幌

Tetsuya Nagata、Takanori Yokota. Recent progress of DNA/RNA heteroduplex oligonucleotide. 第59回日本神経学会学術大会 2018.05.23 札幌

Hiroya Kuwahara、Takanori Yokota. Glyccemic Control Boosts Glucosylated Nanocarrier Crossing the BBB into the Brain. AAN2018 2018.04.22

Noriko Nakamura, Yasutaka Anraku, Hiroya Kuwahara, Takanori Yokota, Kazunori Kataoka. Development of innovative therapeutic nanomachines for intractable neurological diseases. 3rd COINS International Symposium 2016.12.15 Kawasaki

Takanori Yokota. DNA/RNA heteroduplex oligonucleotide for highly efficient gene silencing. 3rd International Conference on Biomaterials Science. 2016.11.30 Tokyo

Yohsuke Yagi, Takuya Ohkubo, Hideya Kawaji, Akira Machida, Haruka Miyata, Saori Goda, Sugata Roy, Yoshihide Hayashizaki, Harukazu Suzuki, Takanori Yokota. Small RNA profiling of cerebrospinal fluid exosomes using next-generation sequencing. American Society for Exosomes and Microvesicles 2016 2016.10.21 California

Kotaro Yoshioka, Yumiko Sujino, Taiki Kunieda, Kie Tanaka, Wenying Piao, Hiroya Kuwahara, Kazutaka Nishina, Tetsuya Nagata, Takanori Yokota. Intracellular mechanisms of microRNA inhibition by a new double-stranded structure for therapeutic oligonucleotide. 12th Annual Meeting of the Oligonucleotide Therapeutics Society 2016.09.27 Montreal

Takanori Yokota. DNA/RNA heteroduplex oligonucleotide. 12th Annual Meeting of the Oligonucleotide Therapeutics Society 2016.09.27 Montreal

Taiki Kunieda, Kotaro Yoshioka, Yumiko Sujino, Kie Tanaka, Wenying Piao, Hiroya Kuwahara, Kazutaka Nishina, Tetsuya Nagata, Takanori Yokota. Pharmacokinetic study of double stranded antisense oligonucleotide: Hetero Chimera Duplex Oligonucleotide (HCDO). 12th Annual Meeting of the Oligonucleotide Therapeutics Society 2016.09.26 Montreal

Takanori Yokota. Propagation of TDP-43 in ALS. Propagation in Neurodegenerative Disease Conference 2016 2016.08.11 Dublin

Yoichiro Nishida, Daishi Yui, Tomoko Nishina, Kaoru Mogushi, Satoru Ishibashi, Itsuki Ajioka, Kinya Ishikawa, Hidehiro Mizusawa, Shigeo Murayama, Takanori Yokota. Enhanced Pla2g3 expression by oxidative stress decreases the IDE and exacerbates AD. Alzheimer's Association International Conference 2016 2016.07.26 Toronto

Fumiko Furukawa, Nobuo Sanjo, Atsushi Kobayashi, Tsuyoshi Hamaguchi, Masahito Yamada, Tetsuyuki Kitamoto, Hidehiro Mizusawa, Takanori Yokota. Colocalization of Aβ42 with PrPSc-plaques in the brain of the Gerstmann-Sträussler-Scheinker disease with the P105L mutation. Alzheimer's Association International Conference 2016 2016.07.24 Toronto

Kazutaka Nishina, Kie Yoshida-Tanaka, Wenying Piao, Takanori Yokota. DNA/RNA heteroduplex oligonucleotide (HDO) for highly efficient gene silencing. The RNA society of Japan 18th annual meeting (The 21st annual meeting of the RNA society) 2016.06.30 Kyoto

Taiki Kunieda, Kotaro Yoshioka, Yumiko Sujino, Kie Tanaka, Wenying Piao, Hiroya Kuwahara, Kazutaka Nishina, Tetsuya Nagata, Takanori Yokota. Development of antisense oligonucleotide with a new type of a double stranded structure. The RNA society of Japan 18th annual meeting (The 21st annual meeting of the RNA society) 2016.06.29 Kyoto

Fumika Sakaue, Eiji Yasuda, Tatsuhiko Sano, Taro Ishiguro, Tetsuya Nagata, Takanori Yokota. Chemically modified RNAs inhibit TDP-43 aggregation. The RNA society of Japan 18th annual meeting (The 21st annual meeting of the RNA society) 2016.06.29 Kyoto

Kotaro Yoshioka, Yumiko Sujino, Taiki Kunieda, Kie Tanaka, Wenying Piao, Hiroya Kuwahara, Kazutaka Nishina, Tetsuya Nagata, Takanori Yokota. A new mechanism of microRNA inhibition by a new type of duplex oligonucleotide. The RNA society of Japan 18th annual meeting (The 21st annual meeting of the RNA society) 2016.06.29 Kyoto

Hiroshi Doi, Shigeru Koyano, Misako Kunii, Shunta Hashiguchi, Hitaru Kishida, Kenichi Tanaka, Masaaki Shiina, Kazuhiro Ogata, Fumiko Hirashima, Yukichi Inoue, Nozomu Sato, Kokoro Ozaki, Kiyobumi Ohta, Takanori Yokota, Hidehiro Mizusawa, Jun Mitsui, Shoji Tsuji, Naomichi Matsumoto, Kinya Ishikawa, Fumiaki Tanaka. The clinical and pathological features of autosomal-dominant SCA with CACNA1G mutation. 57th Annual Meeting of the Japanese Society of Neurology 2016.05.21 Kobe

Keisuke Abe, Mio Tajiri, Daishi Yui, Hiroki Sasaguri, Takuya Ohkubo, Takanori Yokota. A C-terminal fragment of TDP-43 in exosomes mediates propagation of ALS pathology. 57th Annual Meeting of the Japanese Society of Neurology 2016.05.20 Kobe

Masahiko Ichijo, Satoru Ishibashi, Kazunori Miki, Eri Iwasawa, Kyohei Fujita, Hiroaki Yokote, Takeshi Amino, Tomoyuki Kamata, Takanori Yokota. Significance of development and reversion of collaterals in outcome after intravenous thrombolysis. 57th Annual Meeting of the Japanese Society of Neurology 2016.05.20 Kobe

Toshiro Kanazawa, Yurie Nose, Yutaro Asami, Jin Nonami, Masahide Iijima, Hiroaki Tanaka, Takanori Yokota. Clinical features of patients with motor fluctuations before intravenous thrombolysis. 57th Annual Meeting of the Japanese Society of Neurology 2016.05.20 Kobe

Kazumasa Soga, Kinya Ishikawa, Tokuro Huruya, Hidehiro Mizusawa, Takanori Yokota. A clinical and neuropathological study on homozygous mutations with spinocerebellar ataxia type 6. 57th Annual Meeting of the Japanese Society of Neurology 2016.05.20 Kobe

Yoichiro Nishida, Winkler Ethan, Sagare Abhay, De Vivo Darryl, Zlokovic Berislav. GLUT1 reductions at the BBB exacerbate Alzheimer disease vasculo-neuronal dysfunction. 57th Annual Meeting of the Japanese Society of Neurology 2016.05.19 Kobe

Ogata H, Yamasaki R, Oka N, Kuwahara M, Suzuki H, Kusunoki S, Yagi Y, Yokota T, Matsushita T, Kira J-I. Useful laboratory markers for predicting anti-NF155 antibody status among CIDP patients. 57th Annual Meeting of the Japanese Society of Neurology 2016.05.19 Kobe

Kazutaka Nishina, Kotaro Yoshioka, Tomoko Nishina, Hiroya Kuwahara, Tetsuya Nagata, Takanori Yokota. Novel oligonucleotide based on DNA/RNA heteroduplex structures. 57th Annual Meeting of the Japanese Society of Neurology 2016.05.19 Kobe

Kotaro Yoshioka, Taiki Kunieda, Kie Tanaka, Wenying Piao, Hiroya Kuwahara, Kazutaka Nishina, Tetsuya Nagata, Takanori Yokota. A new type of double–stranded structure improved potency of antisense oligonucleotide for FAP. 57th Annual Meeting of the Japanese Society of Neurology 2016.05.19 Kobe

Eri Iwasawa, Satoru Ishibashi, Masahiko Ichijo, Fu Ying Li, Takanori Yokota. Upregulation and distribution of sphingosine-1-phosphate receptor 1 in acute ischemic stroke. 57th Annual Meeting of the Japanese Society of Neurology 2016.05.19 Kobe

Nozomu Sato, Kinya Ishikawa, Hidehiro Mizusawa, Takanori Yokota. Variations in the mutation for spinocerebellar ataxia type 31 require cautious genetic testing. 57th Annual Meeting of the Japanese Society of Neurology 2016.05.19 Kobe

Jindong Song, Tetsuya Nagata, Wenying Piao, Kazutaka Nishina, Takuya Okubo, Keisuke Abe, Masato Hasegawa, Takanori Yokota. Inhibition of alpha-synuclein fibril assembly by antisense oligonucleotide in mice. 57th Annual Meeting of the Japanese Society of Neurology 2016.05.18 Kobe

Fuying Li, Satoru Ishibashi, Kotaro Yoshioka, Takehiko Wada, Masahiko Ichijo, Eri Iwasawa, Jindong Song, Yongquan Zhang, Takanori Yokota. Heteroduplex oligonucleotide reduced gene expression in focal ischemic brain in mice. 57th Annual Meeting of the Japanese Society of Neurology 2016.05.18 Kobe

Nobuo Sanjo, Hidehiro Mizusawa, Takanori Yokota. Various neurological manifestations of lymphoma. 57th Annual Meeting of the Japanese Society of Neurology 2016.05.18 Kobe

Takanori Yokota. DNA/RNA heteroduplex oligonucleotide for highly efficient gene silencing. Oligonucleotide Therapeutics & Delivery 2016.04.04 Boston

Takanori Yokota. DNA/RNA heteroduplex oligonucleotide as a novel concept of therapeutic oligonucleotide. 8th AsiaTIDES Oligonucleotide and Peptide Therapeutics 2016.02.25 Kyoto

Song J, Shimoura T, Kuwahara H, Yoshida-Tanaka K, Nishina K, Nagata T, Yokota T. New platform technology to regulate the blood-brain barrier function in vivo. 第8回CBIR+ONSA共催若手インスパイアシンポジウム 2016.02.20 Tokyo

Asada K, Canestrari E, Fu X, Li Z, Makowski E, Wu YC, Mito JK, Kirsch DG, Baraban J, Paroo Z.. Rescuing dicer Defects via Inhibition of an Anti-dicing Nuclease. The 2nd Annual Meeting of the Japan miRNA Society 2016.02.06 Nagoya

Inagaki M, Uematsu R, Araki Y, Sakamoto S, Ishibashi S, Kashida H, Asanuma H, Yokota T, Wada T. Synthesis and antisense activities of new type of chimeric PRNA-DNA derivatives containing phosphoramidate linkage in PRNA-DNA junction. 2015 International Chemical Congress of Pacific Basin Societies 2015.12.17 Honolulu, HI

Asai M, Uematsu R, Araki Y, Sakamoto S, Ishibashi S, Yokota T, Wada T. Tuning and optimization of on-off switching pH of PRNA for hypoxia specificity. 2015 International Chemical Congress of Pacific Basin Societies 2015.12.17 Honolulu, HI

Yokota T. 2´-DNA/RNA heteroduplex oligonucleotide for highly efficient gene silencing. 2015 International Chemical Congress of Pacific Basin Societies 2015.12.15 Honolulu, HI

Kuwahara H, Shimoura T, Song J, Yoshida-Tanaka K, Nishina K, Nagata T, Yokota T. A new therapeutic oligonucleotide to regulate the blood-brain barrier in vivo. Barcelona BioMed Conference on “Blood Brain Barrier” 2015.11.02 Barcelona, Spain

Sanjo N, Tsukamoto T, Furukawa F, Higuma M, Hizume M, Nakamura Y, Satoh K, Kitamoto T, Yamada M, Yokota T, Mizusawa H. Human prion disease in Japan - a prospective surveillance from 1999. XXII World Congress of Neurology 2015.10.31 Santiago, Chile

Ishiguro T, Sato N, Fujikake N, Ueyama M, Yokota T, Mizusawa H, Wada K, Nagai Y, Ishikawa K. The SCA31-linked UGGAAexp repeat forms RNA foci and is translated into aggregating pentapeptide-repeat proteins in the SCA31 patient brain and Drosophila model. 10th Brain Research Conference 2015.10.15 Chicago, IL

Kuwahara H, Shimoura T, Song J, Yoshida-Tanaka K, Nishina K, Nagata T, Yokota T. A new therapeutic oligonucleotide to regulate the blood-brain barrier. 11th Annual Meeting of the Oligonucleotide Therapeutics Society 2015.10.14 Leiden, Netherlands

Kunieda T, Yoshioka K, Sujino Y, Yoshida-Tanaka K, Piao W, Kuwahara H, Nishina K, Nagata T, Yokota T. Enhancement of potency by gapmer type antisense oligonucleotides with Hetero-Chimera-Duplex-Oligonucleotide (HCDO). 11th Annual Meeting of the Oligonucleotide Therapeutics Society 2015.10.13 Leiden, Netherlands

Yoshioka K, Yoshida-Tanaka K, Piao W, Nishina T, Kuwahara H, Nishina K, Yokota T. Heteroduplex oligonucleotide (HDO): efficient drug delivery and processing mechanism. 11th Annual Meeting of the Oligonucleotide Therapeutics Society 2015.10.13 Leiden, Netherlands

Nagata T, Ihara K, Kaburagi H, Nishina K, Piao W, Yoshida-Tanaka K, Guo H, Kuwahara H, Yoshioka K, Yokota T. The effect of DNA/RNA heteroduplex oligonucleotides in multiple organ systems. 11th Annual Meeting of the Oligonucleotide Therapeutics Society 2015.10.12 Leiden, Netherlands

Furukawa F, Sanjo N, Kobayashi A, Hamaguchi T, Yamada M, Kitamoto T, Mizusawa H, Yokota T. Amyloid-β42 deposition in the brain of the Gerstmann-Sträussler-Scheinker disease with the P105L mutation. Asian Pacific Prion Symposium 2015 2015.09.04 Kanazawa, Japan

Tsukamoto T, Sanjo N, Hamaguchi T, Nakamura Y, Kitamoto T, Yamada M, Mizusawa H. CJD with M232R: Its clinic-pathological features. Asian Pacific Prion Symposium 2015 2015.09.04 Kanazawa, Japan

Sanjo N, Hamaguchi T, Tsukamoto T, Nakamura Y, Kitamoto T, Yamada M, Yokota T, Mizusawa H. Surveillance of prion disease in Japan. Asian Pacific Prion Symposium 2015 2015.09.04 Kanazawa, Japan

Ishiguro T, Fujikake N, Sato N, Ueyama M, Yokota T, Wada K, Mizusawa H, Nagai Y, Ishikawa K.. Expanded UGGAA repeat RNA associated with SCA31 causes progressive neurodegeneration in Drosophila. The 38th Annual Meeting of the Japan Neuroscience Society, 2015.07.29 Kobe, Japan

Higuma M, Sanjo N, Mitoma H, Yokota T. Relationship between attention and gait cycle in the patients with Alzheimer's disease. Alzheimer's Association International Conference 2015 2015.07.18 Washington, DC

Furukawa F, Sanjo N, Higuma M, Kitamoto T, Hizume M, Nakamura Y, Tsukamoto T, Murayama S, Koshi K, Matsukawa T, Tsuji S, Goto J, Yamada M, Mizusawa H, Yokota T . Clinical features in Gerstmann-Straussler-Scheinker syndrome with P105L mutation.. Prion2015 2015.05.26 CO

Hiroya Kuwahara, Takanori Yokota. Development of BBB-targeting nucleic acid medicine. The 37th Annual Meeting of the Japan Neuroscience Society 2014.09.13 Yokohama

Takanori Yokota. Oligonucleotide Gene Therapy for ALS. The 37th Annual Meeting of the Japan Neuroscience Society 2014.09.12 Yokohama

Keisuke Abe, Taku Namatame, Mio Tajiri, Daishi Yui, Takuya Ohkubo, Takanori Yokota. Selective uptake of C-terminal fragments of TDP-43 into exosome. The 37th Annual Meeting of Japan Neuroscience Society 2014.09.12 Yokohama,Japan

Takuya Ohkubo, Akira Machida, Kaoru Mogushi, Hidenori Matsuo, Atsushi Tsunoda, Taketoshi Maehara, Yuichi Noto, Toshio Shimizu, Satoshi Kuwabara, Takashi Kanda, Nobuyoshi Kosaka, Takahiro Ochiya, Takanori Yokota. Profiling of miRNAs in cerebrospinal fluid form patients with multifocal motor neuropathy and amyotrophic lateral sclerosis. The 37th Annual Meeting of the Japan Neuroscience Society 2014.09.11 Yokohama

Sekiguchi T, Kanouchi T, Shibuya K, Noto YI, Yagi Y, Inaba A, Abe K, Misawa S, Orimo S, Kobayashi T, Kamata T, Nakagawa M, Kuwabara S, Mizusawa H, Yokota T. Spreading of amyotrophic lateral sclerosis lesions -multifocal hits & local propagation?. 30th international congress of clinical neurophysiology of the IFCN 2014.03.21 Berlin