Personnel Information

写真a

MORIO Tomohiro


Job title

Professor

Birth date

1958

Laboratory Phone number

+81-3-5803-5245

Laboratory Fax number

+81-3-5803-5245

Research Areas, Keywords

immunodeficiency, infection, class switching, DNA damage response, regenerative medicine

Graduating School 【 display / non-display

  • Tokyo Medical and Dental University, Faculty of Medicine, 1983, Graduated

Degree 【 display / non-display

  • MD, PhD

Campus Career 【 display / non-display

  • 2014.06
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Environmental Response, Pediatrics and Developmental Biology, Professor
  • 2016.04
    -
    Now
    Tokyo Medical and Dental University, Medical Hospital, Hospital Departments, Department of Pediatrics, Maternal and Woman's Medicine, Director
  • 2016.04
    -
    Now
    Tokyo Medical and Dental University, Medical Hospital, Director
  • 2016.10
    -
    Now
    Tokyo Medical and Dental University, Board Member, Director
  • 2019.04
    -
    Now
    Tokyo Medical and Dental University, Medical Hospital, Central Clinical Facilities, Intractable Disease Treatment, Director

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Academic Society Affiliations 【 display / non-display

  • Japan Pediatric Society

  • Japanese Sosiety of Hematology

  • Japanese Society of Hematopoietic Stem Cell Transplantation

  • Japanese Society of Regenerative Medicine

  • Japanese Society for pediatric Infectious Disease

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Academic Activity 【 display / non-display

  • 2006.04
    -
    Now
    Japanese Society of Pediatrics(Councilor)
  • 2008.10
    -
    Now
    Japanese Society for Pediatric Infectious Diseases (Councilor)

Research Areas 【 display / non-display

  • Pediatrics

Qualification Acquired 【 display / non-display

  • Doctor

  • Japanese Society of Pediatrics (Board certified physician)

 

Research Theme 【 display / non-display

  • Initiative on Rare and Undiagnosed Disease(IRUD), 2018.04 - 2021.03

Published Papers & Misc 【 display / non-display

  • Yusuke Imanaka, Maki Taniguchi, Takehiko Doi, Miyuki Tsumura, Rie Nagaoka, Maiko Shimomura, Takaki Asano, Reiko Kagawa, Yoko Mizoguchi, Shuhei Karakawa, Koji Arihiro, Kohsuke Imai, Tomohiro Morio, Jean-Laurent Casanova, Anne Puel, Osamu Ohara, Katsuhiko Kamei, Masao Kobayashi, Satoshi Okada. Inherited CARD9 Deficiency in a Child with Invasive Disease Due to Exophiala dermatitidis and Two Older but Asymptomatic Siblings J Clin Immunol. 2021.07; 41 (5): 975-986. ( PubMed, DOI )

  • Akira Nishimura, Yuki Aoki, Yasuyoshi Ishiwata, Takuya Ichimura, Junichi Ueyama, Yuta Kawahara, Takahiro Tomoda, Maiko Inoue, Kazuaki Matsumoto, Kento Inoue, Haruka Hiroki, Shintaro Ono, Motoi Yamashita, Tsubasa Okano, Mari Tanaka-Kubota, Miho Ashiarai, Satoshi Miyamoto, Reiji Miyawaki, Chika Yamagishi, Mari Tezuka, Teppei Okawa, Akihiro Hoshino, Akifumi Endo, Masato Yasuhara, Takahiro Kamiya, Noriko Mitsuiki, Toshiaki Ono, Takeshi Isoda, Masakatsu Yanagimachi, Daisuke Tomizawa, Masayuki Nagasawa, Shuki Mizutani, Michiko Kajiwara, Masatoshi Takagi, Hirokazu Kanegane, Kohsuke Imai, Tomohiro Morio. Hematopoietic Cell Transplantation with Reduced Intensity Conditioning Using Fludarabine/Busulfan or Fludarabine/Melphalan for Primary Immunodeficiency Diseases. J Clin Immunol. 2021.07; 41 (5): 944-957. ( PubMed, DOI )

  • Motoi Yamashita, Hye Sun Kuehn, Kazuki Okuyama, Satoshi Okada, Yuzaburo Inoue, Noriko Mitsuiki, Kohsuke Imai, Masatoshi Takagi, Hirokazu Kanegane, Masahiro Takeuchi, Naoki Shimojo, Miyuki Tsumura, Aditya K Padhi, Kam Y J Zhang, Bertrand Boisson, Jean-Laurent Casanova, Osamu Ohara, Sergio D Rosenzweig, Ichiro Taniuchi, Tomohiro Morio. A variant in human AIOLOS impairs adaptive immunity by interfering with IKAROS. Nat Immunol. 2021.07; 22 (7): 893-903. ( PubMed, DOI )

  • Motoi Yamashita, Tomohiro Morio. Inborn errors of IKAROS and AIOLOS. Curr Opin Immunol. 2021.07; 72 239-248. ( PubMed, DOI )

  • Shintaro Ono, Kozue Takeshita, Yuko Kiridoshi, Motohiro Kato, Takahiro Kamiya, Akihiro Hoshino, Masakatsu Yanagimachi, Katsuhiro Arai, Ichiro Takeuchi, Nariaki Toita, Toshihiko Imamura, Yoji Sasahara, Junichi Sugita, Kazuko Hamamoto, Masanobu Takeuchi, Shoji Saito, Masaei Onuma, Hiroshi Tsujimoto, Masahiro Yasui, Takashi Taga, Yuki Arakawa, Yuichi Mitani, Nobuyuki Yamamoto, Kohsuke Imai, Wataru Suda, Masahira Hattori, Osamu Ohara, Tomohiro Morio, Kenya Honda, Hirokazu Kanegane. Hematopoietic cell transplantation rescues inflammatory bowel disease and dysbiosis of gut microbiota in XIAP deficiency. J Allergy Clin Immunol Pract. 2021.07; ( PubMed, DOI )

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Conference Activities & Talks 【 display / non-display

  • Rare Diseases and Regenerative Medicine. 2021.03.12

  • A study of adenosine deaminase 2 deficiency by multi-omics analysis. 2021.02.07

  • Delayed recovery of chimeric status after non-myeloablative cord blood transplantation in a patient with DNA ligase IV deficiency. 2021.02.06

  • Inborn Errors of Immunity : Lessons learnt from outliers. 2021.01.26

  • Challenges and Opportunities in Processing of Raw Materials and Cellular and Tissue-based Products at Hospitals. 5th DIA Cell and Gene Therapy Products Symposium in Japan(DIA) 2020.12.11

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