Personnel Information

写真a

Kazuhiro AOKI


Job title

Professor

Birth date

1961

Laboratory Address

No. 217 2nd Fl. Build No.2, 1-5-45, Yushima, Bunkyo-ku, Tokyo

Laboratory Phone number

+81358034641

Laboratory Fax number

+81-3-5803-4641

Mail Address

kazu.hpha@tmd.ac.jp

Homepage URL

http://www.tmd.ac.jp/english/ohe/BOHS_551299de5b5da/index.html

Research Areas, Keywords

Development of bone anabolic agents, non-invasive method of bone augmentation, Development of surface coating materials for the prevention of plaque growth,Research related to the connection between oral bacteria and systemic diseases

Profile

http://www.tmd.ac.jp/english/artis-cms/cms-files/Press_9.pdf

Graduating School 【 display / non-display

  • Tokyo Medical and Dental University, Faculty of Dentistry, Faculty of Dentistry, 1988, Graduated

Graduate School 【 display / non-display

  • Tokyo Medical and Dental University, Graduate School, Division of Dental Research, Dental Pharmacology, Doctor's Course, 1992, Completed

Degree 【 display / non-display

  • Ph.D, Tokyo Medical and Dental University

Campus Career 【 display / non-display

  • 1995.04
    -
    2009.03
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Matrix, Pharmacology, Assistant Professor
  • 2009.04
    -
    2017.01
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Matrix, Pharmacology, Associate Professor
  • 2017.02
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Science and Technology, Basic Oral Health Engineering, Professor

External Career 【 display / non-display

  • 1992.10
    -
    1995.03
    , Dentist
  • 1997.10
    -
    1999.09
    Yale University Faculty of Medicine, Department of Cell Biology, Postdoctoral fellow (Prof. Roland Baron's Lab)
  • 2010.08
    -
    2012.07
    Ministry of Education, , Program officer

Academic Society Affiliations 【 display / non-display

  • American Society of Bone and Mineral Research

  • International Association of Dental Research

  • Japanese Pharmacological Society

Research Areas 【 display / non-display

  • Functional basic dentistry

Qualification Acquired 【 display / non-display

  • Dentist

 

Published Papers & Misc 【 display / non-display

  • Keo P, Matsumoto Y, Shimizu Y, Nagahiro S, Ikeda M, Aoki K, Ono T. A pilot study to investigate the histomorphometric changes of murine maxillary bone around the site of mini-screw insertion in regenerated bone induced by anabolic reagents. European journal of orthodontics. 2020.03; ( PubMed, DOI )

  • Takakura N, Matsuda M, Khan M, Hiura F, Aoki K, Hirohashi Y, Mori K, Yasuda H, Hirata M, Kitamura C, Jimi E. A novel inhibitor of NF-κB-inducing kinase prevents bone loss by inhibiting osteoclastic bone resorption in ovariectomized mice. Bone. 2020.03; 135 115316. ( PubMed, DOI )

  • Shigeki Nagahiro, Tomoki Uehara, Mariko Yamamoto Kawai, Preksa Keo, Hiroki Ochi, Shingo Sato, Shinji Kuroda, Takashi Ono, Michiyo Miyashin, Kazuhiro Aoki. RANKL-binding peptide promotes ectopic bone formation induced by BMP-2 gene transfer in murine gastrocnemius muscle Dental, Oral and Maxillofacial Research. 2020.01; 6 (1): ( DOI )

  • Amano Hitoshi, Iwaki Futoshi, Oki Meiko, Aoki Kazuhiro, Ohba Shinsuke. An osteogenic helioxanthin derivative suppresses the formation of bone-resorbing osteoclasts REGENERATIVE THERAPY. 2019.12; 11 290-296. ( PubMed, DOI )

  • Touyama K, Khan M, Aoki K, Matsuda M, Hiura F, Takakura N, Matsubara T, Harada Y, Hirohashi Y, Tamura Y, Gao J, Mori K, Kokabu S, Yasuda H, Fujita Y, Watanabe K, Takahashi Y, Maki K, Jimi E. Bif-1/Endophilin B1/SH3GLB1 regulates bone homeostasis. Journal of cellular biochemistry. 2019.06; ( PubMed, DOI )

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Conference Activities & Talks 【 display / non-display

  • Kazuhiro Aoki. The peptide drug delivery for bone regeneration. Cutting Edge of Bone and Mineral Research in 2019 2019.12.05 Kyusyu University, Fukuoka, Japan

  • Kazuhiro Aoki. The effects of RANKL-binding peptides on osteoblast differentiation. The 42nd Annual Meeting of the Molecular Biology Society of Japan 2019.12.04 Kitakyusyu, Fukuoka, Japan

  • Yosuke Sasaki, Masud Khan, Kazuhiro Aoki. Development of a suitable scaffold for bone formation using the BMP-2 and osteogenic peptide OP3-4 combination therapy. 2019.11.18 Taipei, Taiwan

  • Yuna Hirohashi, Yuri Shimizu, Masud Khan, Yukihiko Tamura, Kazuhiro Aoki. A new RANKL-binding peptide for the development of the bone anabolic reagent. the 2nd Meeting of International Oral Health Engineering Consortium 2019.11.18 Taipei, Taiwan

  • Nakamura S, Matin K, Aoki K. Histological observations of organs after intravenous injection of Streptococcus mutans. the 41st Annual meeting of Nippon Academy of Dental Technology 2019.11.02 Kanazawa, Ishikawa, Japan

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Awards & Honors 【 display / non-display

  • The 2nd and 3rd prizes of the student competition at the 2nd Meeting of International Oral Health Engineering Consortium (Yosuke Sasaki, Yuna hirohashi),The 2nd International Oral Health Engineering Consortium (Taipei),2019.11

  • The 2nd prize of the student competition at the 1st Meeting of International Oral Health Engineering Consortium (Ayaka Urakawa) ,2018.09

  • New Investigator Award(Uehara T), 13th Congress of the Internatitonal Society of Bone Morphometry,2015.04

Others 【 display / non-display

  • The Wnt agonist R-spondin 3: an unexpected negative regulator of bone formation,2017.11

    Special lecture for PhD course student
    Dr. Kenichi Nagano Department of Oral Medicine, Infection and Innunity, Harvard School of Dental Medicine

 

Social Contribution 【 display / non-display

  • Science Diaglog (Dr. Masud Khan and Prof Kazuhiro Aoki),JSPS,Public school of Sagamihara juniro high school in Kanagawa prefecture,2018.01.20