Published Papers & Misc - KAWASHIMA Nobuyuki

1. 第14回世界歯内療法会議（The 14th IFEA World Endodontic Congress)参加報告 日本歯内療法学会雑誌. 2025.05; 46 (２): 101-107.

2. Yu Z, Kawashima N, Nara SK, Wang S, Han P, Kieu TQ, Ren C, Noda S, Tazawa K, Okiji T. MicroRNA-27a transfected dental pulp stem cells undergo odonto/osteogenic differentiation via targeting DKK3 and SOSTDC1 in Wnt/BMP signaling in vitro and enhance bone formation in vivo. J. Transl. Med.. 2025.02; 23 (1): 189. ( PubMed, DOI )

3. Xu, HC; Nozaki, K; Yu, ZN; Kawashima, N; Ueno, T; Wu, HZ; Wu, H; Wakabayashi, N. Surface functionalization of titanium implants with controlled-release glutathione conjugate for antioxidant and osteogenesis JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T. 2025.01; 34 2872-2884. ( DOI )

4. Ko Nyein Chan, Noda Sonoko, Okada Yamato, Tazawa Kento, Kawashima Nobuyuki, Okiji Takashi. ヒト歯髄幹細胞に対しプレミックスタイプのケイ酸カルシウム系材料が示す生体適合性と石灰化促進作用　in vitro、in vivo実験(Biocompatibility and pro-mineralization effects of premixed calcium silicate-based materials on human dental pulp stem cells: An in vitro and in vivo study) Dental Materials Journal. 2024.09; 43 (5): 729-737. ( ichushi )

5. KO NC, Noda S, Okada Y, Tazawa K, Kawashima N, Okiji T.. Biocompatibility and pro-mineralization effects of premixed calcium silicatebased materials on human dental pulp stem cells: An in vitro and in vivo study Dental Materials Journal. 2024.09; 43 (5): 729-737.

6. Wang S, Kawashima N, Han P, Nara SK, Yu Z, Tazawa K, Fujii M, Kieu TQ, Okiji T. MicroRNA-27a-5p downregulates expression of proinflammatory cytokines in lipopolysaccharide-stimulated human dental pulp cells via the NF-κB signaling pathway Int. J. Mol. Sci.. 2024.09; 25 9694.

7. Kawashima N, Okiji T. Characteristics of inflammatory mediators in dental pulp inflammation and the potential for their control Front. Dent. Med . 2024.08; 5 1426887. ( DOI )

8. Han P, Sunada-Nara K, Kawashima N, Fujii M, Wang S, Kieu TQ, Yu Z, Okiji T. Correction: Han et al. MicroRNA-146b-5p Suppresses Pro-Inflammatory Mediator Synthesis via Targeting TRAF6, IRAK1, and RELA in Lipopolysaccharide-Stimulated Human Dental Pulp Cells. Int. J. Mol. Sci. 2023, 24, 7433. International journal of molecular sciences. 2024.02; 25 (4): 2049. ( PubMed, DOI )

9. Okuda H, Inada M, Konishi T, Kawashima N, Wada T, Okiji T, Uo M. Improvement of the setting properties of mineral trioxide aggregate cements using cellulose nanofibrils. Dent. Mater. J.. 2024.01; 43 (1): 106-111. ( PubMed, DOI )

10. Jin C, Adachi N, Yoshimoto Y, Sasabuchi A, Kawashima N, Ota M S, Iseki S. Fibroblast growth factor signalling regulates the development of tooth root J. Anat.. 2024.01; 244 (6): 1067-1077. ( PubMed, DOI )

11. Okuda Hiroki, Inada Miki, Konishi Tomoya, Kawashima Nobuyuki, Wada Takahiro, Okiji Takashi, Uo Motohiro. セルロースナノファイバーを用いて改善させたmineral trioxide aggregateセメントの硬化特性(Improvement of the setting properties of mineral trioxide aggregate cements using cellulose nanofibrils) Dental Materials Journal. 2024.01; 43 (1): 106-111. ( ichushi )

12. Yahata Y, Handa K, Ohkura N, Okamoto M, Ohshima J, Itoh S, Kawashima N, Tanaka T, Sato N, Noiri Y, Hayashi M, Okiji T, Saito M. Autologous concentrated growth factor mediated accelerated bone healing in root-end microsurgery: A multicenter randomized clinical trial. Regenerative therapy. 2023.12; 24 377-384. ( PubMed, DOI )

13. Yahata Yoshio, Handa Keisuke, Ohkura Naoto, Okamoto Motoki, Ohshima Jun, Itoh Shusaku, Kawashima Nobuyuki, Tanaka Toshinori, Sato Nobuya, Noiri Yuichiro, Hayashi Mikako, Okiji Takashi, Saito Masahiro. 自家成長因子濃縮物は根尖の顕微鏡下手術での骨治癒加速を媒介する　多施設共同無作為化比較試験(Autologous concentrated growth factor mediated accelerated bone healing in root-end microsurgery: A multicenter randomized clinical trial) Regenerative Therapy. 2023.12; 24 377-384. ( ichushi )

14. Alchawoosh A, Hashimoto K, Kawashima N, Noda S, Nozaki K, Okiji T. Hydraulic calcium silicate-based root canal sealers mitigate proinflammatory cytokine synthesis and promote osteogenesis in vitro. Journal of dental sciences. 2023.10; 18 (4): 1731-1739. ( PubMed, DOI )

15. Han P, Sunada-Nara K, Kawashima N, Fujii M, Wang S, Kieu TQ, Yu Z, Okiji T. MicroRNA-146b-5p suppresses pro-inflammatory mediator synthesis via targeting TRAF6, IRAK1, and RELA in lipopolysaccharide-stimulated human dental pulp cells. Int J Mol Sci. 2023.04; 24 (8): 7433. ( PubMed, DOI )

16. Okuda H, Inada M, Konishi T, Kawashima N, Wada T, Okiji T, Uo M. Improvement of the setting properties of mineral trioxide aggregate cements using cellulose nanofibrils Dent Mat J. 2023; in press

17. Zaw ZCT, Kawashima N, Kaneko T, Okiji T. Angiogenesis during coronal pulp regeneration using rat dental pulp cells: Neovascularization in rat molars in vivo and proangiogenic dental pulp cell-endothelial cell interactions in vitro. Journal of dental sciences. 2022.07; 17 (3): 1160-1168. ( PubMed, DOI )

18. Adel S, Hashimoto K, Kawashima N, Wada T, Uo M, Okiji T. Biocompatibility and pro-mineralization effect of tristrontium aluminate cement for endodontic use. Journal of dental sciences. 2022.07; 17 (3): 1193-1200. ( PubMed, DOI )

19. Kieu TQ, Tazawa K, Kawashima N, Noda S, Fujii M, Nara K, Hashimoto K, Han P, Okiji T. Kinetics of LYVE-1-positive M2-like macrophages in developing and repairing dental pulp in vivo and their pro-angiogenic activity in vitro. Scientific reports. 2022.03; 12 (1): 5176. ( PubMed, DOI )

20. Thein HSS, Hashimoto K, Kawashima N, Noda S, Okiji T. Evaluation of the anti-inflammatory effects of surface-reaction-type pre-reacted glass-ionomer filler containing root canal sealer in lipopolysaccharide-stimulated RAW264.7 macrophages. Dental materials journal. 2022.02; 41 (1): 150-158. ( PubMed, DOI )

21. Dumrongvute K, Adel S, Wada T, Kawashima N, Piyachon C, Kurabayashi T, Okiji T, Uo M . Distrontium cerate as a radiopaque component of hydraulic endodontic cement Materials (Basel, Switzerland). 2022.01; 15 (284): ( DOI )

22. Adel S, Hashimoto K, Kawashima N, Wada T, Uo M, Okiji T. Biocompatibility and pro-mineralization effect of tristrontium aluminate cement for endodontic use Journal of Dental Sciences. 2022.01; ( DOI )

23. Orikasa S, Kawashima N, Tazawa K, Hashimoto K, Sunada-Nara K, Noda S, Fujii M, Akiyama T, Okiji T. Hypoxia-inducible factor 1α induces osteo/odontoblast differentiation of human dental pulp stem cells via Wnt/β-catenin transcriptional cofactor BCL9. Scientific reports. 2022.01; 12 (1): 682. ( PubMed, DOI )

24. Okada Y, Kawashima N, Nod S, Murano H, Han P, Hashimoto K, Kaneko T, Okiji T. VEGFA promotes odonto/osteoblastic differentiation in dental pulp stem cells via ERK/p38 signaling Journal of Dental Sciences. 2022; in press ( DOI )

25. Dumrongvute K, Adel S, Wada T, Kawashima N, Piyachon C, Watanabe H, Kurabayashi T, Okiji T, Uo M. Distrontium Cerate as a Radiopaque Component of Hydraulic Endodontic Cement. Materials (Basel, Switzerland). 2021.12; 15 (1): ( PubMed, DOI )

26. Sunada-Nara Keisuke, Kawashima Nobuyuki, Okiji Takashi. Micro-endodontic management of a fused mandibular molar with rare anatomical features: a case report Micro: the International Journal of Microdentistry. 2021.11; 12 (2): 70-76. ( ichushi )

27. Zaw ZCT, Kawashima N, Kaneko T, Okii T. Angiogenesis during coronal pulp regeneration using rat dental pulp cells: neovascularization in rat molars in vivo and proangiogenic dental pulp cell-endothelial cell interactions in vitro Journal of Dental Sciences. 2021.07; in press

28. Phyo YS, Hashimoto K, Kawashima N, Kuramoto M, Okiji T. Evaluation of the cytocompatibility of methacrylate resin-based root canal sealers with osteoblast-like cells. Dental materials journal. 2021.07; 40 (4): 942-948. ( PubMed, DOI )

29. Adel S, Wada T, Kawashima N, Abdou A, Watanabe H, Kurabayashi T, Okiji T, Uo M. Preparation and properties of tristrontium aluminate as an alternative component of mineral trioxide aggregate (MTA) cement. Dental materials journal. 2021.01; 40 (1): 184-190. ( PubMed, DOI )

30. Phyo Y, Hashimoto K, Kawashima N, Kuramoto M, Okiji T. Evaluation of the cytocompatibility of methacrylate resin-based root canal sealers with osteoblast-like cell Dental Materials Journal. 2021;

31. Kuramoto M, Kawashima N, Tazawa K, Nara K, Fujii M, Noda S, Hashimoto K, Nozaki K, Okiji T. Mineral trioxide aggregate suppresses pro-inflammatory cytokine expression via the calcineurin/nuclear factor of activated T cells/early growth response 2 pathway in lipopolysaccharide-stimulated macrophages. International endodontic journal. 2020.12; 53 (12): 1653-1665. ( PubMed, DOI )

32. Kawashima N, Hashimoto K, Kuramoto M, Bakhit A, Wakabayashi Y, Okiji T. A Novel Bioactive Endodontic Sealer Containing Surface-Reaction-Type Prereacted Glass-Ionomer Filler Induces Osteoblast Differentiation. Materials (Basel, Switzerland). 2020.10; 13 (20): ( PubMed, DOI )

33. Tazawa K, Kawashima N, Kuramoto M, Noda S, Fujii M, Nara K, Hashimoto K, Okiji T. Transient Receptor Potential Ankyrin 1 (TRPA1) is Up-Regulated in Response to Lipopolysaccharide via P38/ Mitogen-Activated Protein Kinase (MAPK) in Dental Pulp Cells and Promotes Mineralization. The American journal of pathology. 2020.09; 190 (12): 2417-2426. ( PubMed, DOI )

34. Fujii M, Kawashima N, Tazawa K, Hashimoto K, Nara K, Noda S, Nagai S, Okiji T. Hypoxia-inducible factor 1α promotes interleukin 1β and tumour necrosis factor α expression in lipopolysaccharide-stimulated human dental pulp cells. International endodontic journal. 2020.05; 53 (5): 636-646. ( PubMed, DOI )

35. Bakhit A, Kawashima N, Hashimoto K, Noda S, Nara K, Kuramoto M, Tazawa K, Okiji T. Author Correction: Strontium ranelate promotes odonto-/osteogenic differentiation/mineralization of dental papillae cells in vitro and mineralized tissue formation of the dental pulp in vivo. Scientific reports. 2020.05; 10 (1): 8375. ( PubMed, DOI )

36. Nara K, Kawashima N, Noda S, Fujii M, Hashimoto K, Tazawa K, Okiji T. Anti-inflammatory roles of microRNA 21 in lipopolysaccharide-stimulated human dental pulp cells. Journal of Cellular Physiology.. 2019.11; 234 (11): 21331-21341. ( PubMed, DOI )

37. Fujii M, Kawashima N, Tazawa K, Hashimoto K, Nara K, Noda S, Kuramoto M, Orikasa S, Nagai S, Okiji T . HIF1α inhibits LPS-mediated induction of IL-6 synthesis via SOCS3-dependent CEBPβ suppression in human dental pulp cells Biochemical and Biophysical Research Communications . 2019.11; 522 (2): 308-314. ( PubMed, DOI )

38. Noda S, Kawashima N, Yamamoto M, Hashimoto K, Nara K, Sekiya I, Okiji T. Effect of cell culture density on dental pulp-derived mesenchymal stem cells with reference to osteogenic differentiation. Scientific Reports. 2019.04; 9 (1): 5430. ( PubMed, DOI )

39. Hirai K, Furusho H, Kawashima N, Xu S, de Beer MC, Battaglino R, Van Dyke T, Stashenko P, Sasaki H. Serum amyloid A contributes to chronic apical periodontitis via TLR2 and TLR4 Journal of Dental Research. 2019.01; 98 (1): 117-125. ( PubMed, DOI )

40. Bakhit A, Kawashima N, Hashimoto K, , Noda S, Nara K, , Kuramoto M, Tazawa K, Okiji T. Strontium ranelate promotes odonto-/osteogenic differentiation/mineralization of dental papillae cells in vitro and mineralized tissue formation of the dental pulp in vivo. Scientific Reports. 2018.06; ( PubMed, DOI )

41. Hashimoto K, Kawashima N, Ichinose S, Nara K, Noda S, Okiji T. EDTA Treatment for Sodium Hypochlorite-treated Dentin Recovers Disturbed Attachment and Induces Differentiation of Mouse Dental Papilla Cells. Journal of Endodontics. 2018.02; 44 (2): 256-262. ( PubMed, DOI )

42. バキト・アラムッヂン , 川島 伸之, 橋本 健太郎, 野田 園子, 奈良 圭介, 興地 隆史. ラネル酸ストロンチウムによるマウス歯乳頭細胞の増殖および石灰化はカルシウム感知受容体を介して誘導される 特定非営利活動法人日本歯科保存学会学術大会プログラムおよび講演抄録集. 2017.10; 147回 63. ( ichushi )

43. Kawashima N, Noda S, Yamamoto M, Okiji T. Properties of dental pulp-derived mesenchymal stem cells and the effects of culture conditions. Journal of Endodontics. 2017.09; 43 (9S): S31-S34. ( PubMed, DOI )

44. Kawashima Nobuyuki, Okiji Takashi. 象牙芽細胞　象牙質-歯髄複合体における特殊な硬組織形成細胞(Odontoblasts: Specialized hard-tissue-forming cells in the dentin-pulp complex) Congenital Anomalies. 2017.07; 56 (4): 144-153. ( ichushi )

45. Kento Tazawa, Hideharu Ikeda, Nobuyuki Kawashima, Takashi Okiji. Transient receptor potential melastatin (TRPM) 8 is expressed in freshly isolated native human odontoblasts. Archives of Oral Biology. 2016.12; 75 55-61. ( PubMed, DOI )

46. Kawashima N, Okiji T. Odontoblasts: Specialized hard-tissue-forming cells in the dentin-pulp complex Congenital Anomalies (Kyoto). 2016.07; 56 (4): 144-153. ( PubMed, DOI )

47. Suzuki N, Takimoto K, Kawashima N. Cathepsin K inhibitor regulates inflammation and bone destruction in experimentally induced rat periapical lesions Journal of Endodontics. 2015.09; 41 (9): 1474-1479. ( PubMed, DOI )

48. Zhou M, Kawashima N, Suzuki N, Yamamoto M, Ohnishi O, Katsube K, Tanabe H, Kudo A, Saito M, Suda H. Periostin is a negative regulator of mineralization in the dental pulp tissue Odontology. 2015.05; 103 (2): 152-159. ( PubMed, DOI )

49. Takimoto K, Kawashima N, Suzuki N, Koizumi Y, Yamamoto M, Nakashima M, Suda Heaki. Down-regulation of inflammatory mediator synthesis and infiltration of inflammatory cells by MMP-3 in experimentally-induced rat pulpitis Journal of Endodontics. 2014.09; 40 (9): 1404-1409. ( DOI )

50. Yamamoto M, Kawashima N, Takashino N, Koizumi Y, Takimoto K, Suzuki N, Saito M, Suda H. Three-dimensional spheroid culture promotes odonto/osteoblastic differentiation of dental pulp cells Archives of Oral Biology. 2014.03; 59 (3): 310-317. ( DOI )

51. Wei S, Kawashima N, Suzuki N, Xu J, Takahashi S, Zhou M, Koizumi Y, Suda H. Kinetics of Th17-related cytokine expression in experimentally induced rat periapical lesions Australian Endodontic Journal. 2013.12; 39 (3): 164-170. ( DOI )

52. 11. Yoshida T, Iwata T, Umemoto T, Shiratsuchi Y, Kawashima N, Sugiyama T, Yamato M and Okano T. Promotion of mouse ameloblast proliferation by Lgr5 mediated integrin signaling Journal of Cellular Biochemistry. 2013.09; 114 (9): 2138-2147. ( DOI )

53. Koizumi Yu, Kawashima Nobuyuki, Yamamoto Mioko, Takimoto Koyo, Zhou Mengyu, Suzuki Noriyuki, Saito Masahiro, Harada Hidemitsu, Suda Hideaki. Wnt11 expression in rat dental pulp and promotional effects of Wnt signaling on odontoblast differentiation Congenital Anomalies. 2013.09; 53 (3): 101-108. ( DOI )

54. Yoshida T., Kumashiro Y., Iwata T., Ishihara J., Umemoto T., Shiratsuchi Y., Kawashima N., Sugiyama T., Yamato M., Okano T.. Requirement of integrin beta 3 for iron transportation during enamel formation Journal of Dental Research. 2012.12; 91 (12): 1154-1159. ( DOI )

55. Kawashima N. Characterisation of dental pulp stem cells: A new horizon for tissue regeneration? Archives of Oral Biology. 2012.11; 57 (11): 1439-1458. ( DOI )

56. Xu J, Kawashima N, Fujiwara N, Harada H, Ota MS, Suda H. Promotional effects of vasoactive intestinal peptide on the development of rodent Hertwig's epithelial root sheath Congenital Anomalies. 2012.09; 52 (3 SI): 162-167. ( PubMed, DOI )

57. Sun H, Yang J, Kawashima N, Li Y, Zhang W, Wang P. A brief comparison of curricula at dental schools in China and Japan Journal of Dental Education. 2012.06; 76 (6): 765-773.

58. Bolortuya Gombo, Ebihara Arata, Ichinose Shizuko, Watanabe Satoshi, Anjo Tomoo, Kokuzawa Chizuko, Saegusa Hidetoshi, Kawashima Nobuyuki, Suda Hideaki. Effects of Dentin Surface Modifications Treated with Er:YAG and Nd:YAG Laser Irradiation on Fibroblast Cell Adhesion PHOTOMEDICINE AND LASER SURGERY. 2012.02; 30 (2): 63-70. ( DOI )

59. Bolortuya G., Ebihara A., Ichinose S., Watanabe S., Anjo T., Kokuzawa C., Saegusa H., Kawashima N., Suda H.. Initial fibroblast attachment to Erbium:YAG laser-irradiated dentine INTERNATIONAL ENDODONTIC JOURNAL. 2011.12; 44 (12): 1134-1144. ( DOI )

60. Wang HG., Kawashima N., Iwata T., Xu J., Takahashi S., Sugiyama T., Suda H.. MEPE activated by furin promotes pulpal cell adhesion Journal of Dental Research. 2011.04; 90 (4): 529-534. ( DOI )

61. Wang S, Kawashima N, Sakamoto K, Katsube K, Umezawa A, Suda H. Osteogenic differentiation of mouse mesenchymal progenitor cell, Kusa-A1 is promoted by mammalian transcriptional repressor Rbpj Biochemical and Biophysical Research Communications. 2010.09; 400 (1): 39-45. ( PubMed, DOI )

62. Sun H, Kawashima N, Xu J, Takahashi S, Suda H. Expression of Notch signalling-related genes in normal and differentiating rat dental pulp cells Australian Endodontic Journal. 2010.08; 36 (2): 54-58. ( PubMed, DOI )

63. Wang H, Kawashima N, Iwata T, Xu J, Takahashi S, Sugiyama T, Suda H. Differentiation of odontoblasts is negatively regulated by MEPE via its C-terminal fragment. Biochemical and Biophysical Research Communications. 2010.07; 398 (3): 406-412. ( PubMed, DOI )

64. Kawashima N, Wadachi R, Suda H, Yeng T, Parashos P.. Root canal medicaments. International Dental Journal. 2009.02; 59 (1): 5-11. ( PubMed )

65. Kabasawa Y., Nagumo K., Takeda Y., Kawashima N., Okada N., Omura K., Yamaguchi A., Katsube K.. Amelogenin positive cells scattered in the interstitial component of odontogenic fibromas Journal of Clinical Pathology. 2008.07; 61 (7): 851-855. ( PubMed, DOI )

66. Sasaki H, Suzuki N, Kent R, Kawashima N, Takeda J, Stashenko P. T cell response mediated by myeloid cell-derived IL-12 is responsible for Porphyromonas gingivalis-induced periodontitis in IL-10-deficient mice. Journal of Immunology. 2008.05; 180 (9): 6193-6198. ( PubMed )

67. Kawashima N, Suzuki N, Yang G, Ohi C, Okuhara S, Nakano-Kawanishi H, Suda H. Kinetics of RANKL, RANK and OPG expressions in experimentally induced rat periapical lesions Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 2007.05; 103 (5): 707-711. ( PubMed, DOI )

68. Satomi Takahashi, Nobuyuki Kawashima, Kei Sakamoto, Akira Nakata, Takashi Kameda, Toshihiro Sugiyama, Ken-ichi Katsube, Hideaki Suda. Differentiation of an ameloblast-lineage cell line (ALC) is induced by Sonic hedgehog signaling. Biochem. Biophys. Res. Commun.. 2007.02; 353 (2): 405-411. ( PubMed, DOI )

69. Guangyan Yang, Nobuyuki Kawashima, Tomoatsu Kaneko, Noriyuki Suzuki, Takashi Okiji, Hideaki Suda. Kinetic study of immunohistochemical colocalization of antigen-presenting cells and nerve fibers in rat periapical lesions. J Endod. 2007.02; 33 (2): 132-136. ( PubMed, DOI )

70. Nobuyuki Kawashima, Indra Wongyaofa, Noriyuki Suzuki, Hiromi Nakano Kawanishi, Hideaki Suda. NK and NKT cells in the rat dental pulp tissues. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006.10; 102 (4): 558-563. ( PubMed, DOI )

71. Jian Zhang, Nobuyuki Kawashima, Hideaki Suda, Yukiko Nakano, Yoshiro Takano, Miyuki Azuma. The existence of CD11c+ sentinel and F4/80+ interstitial dendritic cells in dental pulp and their dynamics and functional properties. Int. Immunol.. 2006.09; 18 (9): 1375-1384. ( PubMed, DOI )

72. N Kawashima, H Nakano-Kawanishi, N Suzuki, M Takagi, H Suda. Effect of NOS inhibitor on cytokine and COX2 expression in rat pulpitis. J. Dent. Res.. 2005.08; 84 (8): 762-767. ( PubMed )

73. Nobuyuki Kawashima, Kentaro Shindo, Kei Sakamoto, Hisatomo Kondo, Akihiro Umezawa, Shohei Kasugai, Bernard Perbal, Hideaki Suda, Minoru Takagi, Ken-ichi Katsube. Molecular and cell biological properties of mouse osteogenic mesenchymal progenitor cells, Kusa. J. Bone Miner. Metab.. 2005; 23 (2): 123-133. ( PubMed, DOI )

74. Kawanishi HK, Kawashima N, Suzuki N, Suda H, Takagi M. Effects of an inducible nitric oxide synthase inhibitor on experimentally induced rat EUROPEAN JOURNAL OF ORAL SCIENCES. 2004.08; 112 (4): 332-337. ( DOI )

75. Hajime Sasaki, Khaled Balto, Nobuyuki Kawashima, Jean Eastcott, Katsuaki Hoshino, Shizuo Akira, Philip Stashenko. Gamma interferon (IFN-gamma) and IFN-gamma-inducing cytokines interleukin-12 (IL-12) and IL-18 do not augment infection-stimulated bone resorption in vivo. Clin. Diagn. Lab. Immunol.. 2004.01; 11 (1): 106-110. ( PubMed )

76. Kentaro Shindo, Nobuyuki Kawashima, Kei Sakamoto, Akira Yamaguchi, Akihiro Umezawa, Minoru Takagi, Ken-ichi Katsube, Hideaki Suda. Osteogenic differentiation of the mesenchymal progenitor cells, Kusa is suppressed by Notch signaling. Exp. Cell Res.. 2003.11; 290 (2): 370-380. ( PubMed )

77. N Kawashima, P Stashenko. Expression of bone-resorptive and regulatory cytokines in murine periapical inflammation. Arch. Oral Biol.. 1999.01; 44 (1): 55-66. ( PubMed )

78. A M Kamal, T Okiji, N Kawashima, H Suda. Defense responses of dentin/pulp complex to experimentally induced caries in rat molars: an immunohistochemical study on kinetics of pulpal Ia antigen-expressing cells and macrophages. J Endod. 1997.02; 23 (2): 115-120. ( PubMed )

79. N Kawashima, T Okiji, T Kosaka, H Suda. Kinetics of macrophages and lymphoid cells during the development of experimentally induced periapical lesions in rat molars: a quantitative immunohistochemical study. J Endod. 1996.06; 22 (6): 311-316. ( PubMed, DOI )

80. T Okiji, T Kosaka, A M Kamal, N Kawashima, H Suda. Age-related changes in the immunoreactivity of the monocyte/macrophage system in rat molar pulp. Arch. Oral Biol.. 1996.05; 41 (5): 453-460. ( PubMed )

81. T Okiji, N Kawashima, T Kosaka, C Kobayashi, H Suda. Distribution of Ia antigen-expressing nonlymphoid cells in various stages of induced periapical lesions in rat molars. J Endod. 1994.01; 20 (1): 27-31. ( PubMed )

82. T Okiji, I Morita, N Kawashima, T Kosaka, H Suda, S Murota. Immunohistochemical detection of prostaglandin I2 synthase in various calcified tissue-forming cells in rat. Arch. Oral Biol.. 1993.01; 38 (1): 31-36. ( PubMed )

83. T Okiji, N Kawashima, T Kosaka, A Matsumoto, C Kobayashi, H Suda. An immunohistochemical study of the distribution of immunocompetent cells, especially macrophages and Ia antigen-expressing cells of heterogeneous populations, in normal rat molar pulp. J. Dent. Res.. 1992.05; 71 (5): 1196-1202. ( PubMed )