Published Papers & Misc - KAWASHIMA Nobuyuki

1. 第14回世界歯内療法会議（The 14th IFEA World Endodontic Congress)参加報告 日本歯内療法学会雑誌. 2025.05; 46 (２): 101-107.

2. Yu Z, Kawashima N, Nara SK, Wang S, Han P, Kieu TQ, Ren C, Noda S, Tazawa K, Okiji T. MicroRNA-27a transfected dental pulp stem cells undergo odonto/osteogenic differentiation via targeting DKK3 and SOSTDC1 in Wnt/BMP signaling in vitro and enhance bone formation in vivo. J. Transl. Med.. 2025.02; 23 (1): 189. ( PubMed, DOI )

3. Xu, HC; Nozaki, K; Yu, ZN; Kawashima, N; Ueno, T; Wu, HZ; Wu, H; Wakabayashi, N. Surface functionalization of titanium implants with controlled-release glutathione conjugate for antioxidant and osteogenesis JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T. 2025.01; 34 2872-2884. ( DOI )

4. Ko Nyein Chan, Noda Sonoko, Okada Yamato, Tazawa Kento, Kawashima Nobuyuki, Okiji Takashi. ヒト歯髄幹細胞に対しプレミックスタイプのケイ酸カルシウム系材料が示す生体適合性と石灰化促進作用　in vitro、in vivo実験(Biocompatibility and pro-mineralization effects of premixed calcium silicate-based materials on human dental pulp stem cells: An in vitro and in vivo study) Dental Materials Journal. 2024.09; 43 (5): 729-737. ( ichushi )

5. KO NC, Noda S, Okada Y, Tazawa K, Kawashima N, Okiji T.. Biocompatibility and pro-mineralization effects of premixed calcium silicatebased materials on human dental pulp stem cells: An in vitro and in vivo study Dental Materials Journal. 2024.09; 43 (5): 729-737.

6. Wang S, Kawashima N, Han P, Nara SK, Yu Z, Tazawa K, Fujii M, Kieu TQ, Okiji T. MicroRNA-27a-5p downregulates expression of proinflammatory cytokines in lipopolysaccharide-stimulated human dental pulp cells via the NF-κB signaling pathway Int. J. Mol. Sci.. 2024.09; 25 9694.

7. Kawashima N, Okiji T. Characteristics of inflammatory mediators in dental pulp inflammation and the potential for their control Front. Dent. Med . 2024.08; 5 1426887. ( DOI )

8. Han P, Sunada-Nara K, Kawashima N, Fujii M, Wang S, Kieu TQ, Yu Z, Okiji T. Correction: Han et al. MicroRNA-146b-5p Suppresses Pro-Inflammatory Mediator Synthesis via Targeting TRAF6, IRAK1, and RELA in Lipopolysaccharide-Stimulated Human Dental Pulp Cells. Int. J. Mol. Sci. 2023, 24, 7433. International journal of molecular sciences. 2024.02; 25 (4): 2049. ( PubMed, DOI )

9. Okuda H, Inada M, Konishi T, Kawashima N, Wada T, Okiji T, Uo M. Improvement of the setting properties of mineral trioxide aggregate cements using cellulose nanofibrils. Dent. Mater. J.. 2024.01; 43 (1): 106-111. ( PubMed, DOI )

10. Jin C, Adachi N, Yoshimoto Y, Sasabuchi A, Kawashima N, Ota M S, Iseki S. Fibroblast growth factor signalling regulates the development of tooth root J. Anat.. 2024.01; 244 (6): 1067-1077. ( PubMed, DOI )

11. Okuda Hiroki, Inada Miki, Konishi Tomoya, Kawashima Nobuyuki, Wada Takahiro, Okiji Takashi, Uo Motohiro. セルロースナノファイバーを用いて改善させたmineral trioxide aggregateセメントの硬化特性(Improvement of the setting properties of mineral trioxide aggregate cements using cellulose nanofibrils) Dental Materials Journal. 2024.01; 43 (1): 106-111. ( ichushi )

12. Yahata Y, Handa K, Ohkura N, Okamoto M, Ohshima J, Itoh S, Kawashima N, Tanaka T, Sato N, Noiri Y, Hayashi M, Okiji T, Saito M. Autologous concentrated growth factor mediated accelerated bone healing in root-end microsurgery: A multicenter randomized clinical trial. Regenerative therapy. 2023.12; 24 377-384. ( PubMed, DOI )

13. Yahata Yoshio, Handa Keisuke, Ohkura Naoto, Okamoto Motoki, Ohshima Jun, Itoh Shusaku, Kawashima Nobuyuki, Tanaka Toshinori, Sato Nobuya, Noiri Yuichiro, Hayashi Mikako, Okiji Takashi, Saito Masahiro. 自家成長因子濃縮物は根尖の顕微鏡下手術での骨治癒加速を媒介する　多施設共同無作為化比較試験(Autologous concentrated growth factor mediated accelerated bone healing in root-end microsurgery: A multicenter randomized clinical trial) Regenerative Therapy. 2023.12; 24 377-384. ( ichushi )

14. Alchawoosh A, Hashimoto K, Kawashima N, Noda S, Nozaki K, Okiji T. Hydraulic calcium silicate-based root canal sealers mitigate proinflammatory cytokine synthesis and promote osteogenesis in vitro. Journal of dental sciences. 2023.10; 18 (4): 1731-1739. ( PubMed, DOI )

15. Han P, Sunada-Nara K, Kawashima N, Fujii M, Wang S, Kieu TQ, Yu Z, Okiji T. MicroRNA-146b-5p suppresses pro-inflammatory mediator synthesis via targeting TRAF6, IRAK1, and RELA in lipopolysaccharide-stimulated human dental pulp cells. Int J Mol Sci. 2023.04; 24 (8): 7433. ( PubMed, DOI )

16. Okuda H, Inada M, Konishi T, Kawashima N, Wada T, Okiji T, Uo M. Improvement of the setting properties of mineral trioxide aggregate cements using cellulose nanofibrils Dent Mat J. 2023; in press

17. Zaw ZCT, Kawashima N, Kaneko T, Okiji T. Angiogenesis during coronal pulp regeneration using rat dental pulp cells: Neovascularization in rat molars in vivo and proangiogenic dental pulp cell-endothelial cell interactions in vitro. Journal of dental sciences. 2022.07; 17 (3): 1160-1168. ( PubMed, DOI )

18. Adel S, Hashimoto K, Kawashima N, Wada T, Uo M, Okiji T. Biocompatibility and pro-mineralization effect of tristrontium aluminate cement for endodontic use. Journal of dental sciences. 2022.07; 17 (3): 1193-1200. ( PubMed, DOI )

19. Kieu TQ, Tazawa K, Kawashima N, Noda S, Fujii M, Nara K, Hashimoto K, Han P, Okiji T. Kinetics of LYVE-1-positive M2-like macrophages in developing and repairing dental pulp in vivo and their pro-angiogenic activity in vitro. Scientific reports. 2022.03; 12 (1): 5176. ( PubMed, DOI )

20. Thein HSS, Hashimoto K, Kawashima N, Noda S, Okiji T. Evaluation of the anti-inflammatory effects of surface-reaction-type pre-reacted glass-ionomer filler containing root canal sealer in lipopolysaccharide-stimulated RAW264.7 macrophages. Dental materials journal. 2022.02; 41 (1): 150-158. ( PubMed, DOI )