Jin C, Adachi N, Yoshimoto Y, Sasabuchi A, Kawashima N, Ota M S, Iseki S. Fibroblast growth factor signalling regulates the development of tooth root J. Anat.. 2024.01; 244 (6): 1067-1077. ( PubMed, DOI )

Yahata Y, Handa K, Ohkura N, Okamoto M, Ohshima J, Itoh S, Kawashima N, Tanaka T, Sato N, Noiri Y, Hayashi M, Okiji T, Saito M. Autologous concentrated growth factor mediated accelerated bone healing in root-end microsurgery: A multicenter randomized clinical trial. Regenerative therapy. 2023.12; 24 377-384. ( PubMed, DOI )

Yahata Yoshio, Handa Keisuke, Ohkura Naoto, Okamoto Motoki, Ohshima Jun, Itoh Shusaku, Kawashima Nobuyuki, Tanaka Toshinori, Sato Nobuya, Noiri Yuichiro, Hayashi Mikako, Okiji Takashi, Saito Masahiro. 自家成長因子濃縮物は根尖の顕微鏡下手術での骨治癒加速を媒介する　多施設共同無作為化比較試験(Autologous concentrated growth factor mediated accelerated bone healing in root-end microsurgery: A multicenter randomized clinical trial) Regenerative Therapy. 2023.12; 24 377-384. ( ichushi )

Alchawoosh A, Hashimoto K, Kawashima N, Noda S, Nozaki K, Okiji T. Hydraulic calcium silicate-based root canal sealers mitigate proinflammatory cytokine synthesis and promote osteogenesis in vitro. Journal of dental sciences. 2023.10; 18 (4): 1731-1739. ( PubMed, DOI )

Han P, Sunada-Nara K, Kawashima N, Fujii M, Wang S, Kieu TQ, Yu Z, Okiji T. MicroRNA-146b-5p suppresses pro-inflammatory mediator synthesis via targeting TRAF6, IRAK1, and RELA in lipopolysaccharide-stimulated human dental pulp cells. Int J Mol Sci. 2023.04; 24 (8): 7433. ( PubMed, DOI )

Okuda H, Inada M, Konishi T, Kawashima N, Wada T, Okiji T, Uo M. Improvement of the setting properties of mineral trioxide aggregate cements using cellulose nanofibrils Dent Mat J. 2023; in press

Zaw ZCT, Kawashima N, Kaneko T, Okiji T. Angiogenesis during coronal pulp regeneration using rat dental pulp cells: Neovascularization in rat molars in vivo and proangiogenic dental pulp cell-endothelial cell interactions in vitro. Journal of dental sciences. 2022.07; 17 (3): 1160-1168. ( PubMed, DOI )

Adel S, Hashimoto K, Kawashima N, Wada T, Uo M, Okiji T. Biocompatibility and pro-mineralization effect of tristrontium aluminate cement for endodontic use. Journal of dental sciences. 2022.07; 17 (3): 1193-1200. ( PubMed, DOI )

Kieu TQ, Tazawa K, Kawashima N, Noda S, Fujii M, Nara K, Hashimoto K, Han P, Okiji T. Kinetics of LYVE-1-positive M2-like macrophages in developing and repairing dental pulp in vivo and their pro-angiogenic activity in vitro. Scientific reports. 2022.03; 12 (1): 5176. ( PubMed, DOI )

Thein HSS, Hashimoto K, Kawashima N, Noda S, Okiji T. Evaluation of the anti-inflammatory effects of surface-reaction-type pre-reacted glass-ionomer filler containing root canal sealer in lipopolysaccharide-stimulated RAW264.7 macrophages. Dental materials journal. 2022.02; 41 (1): 150-158. ( PubMed, DOI )

Dumrongvute K, Adel S, Wada T, Kawashima N, Piyachon C, Kurabayashi T, Okiji T, Uo M . Distrontium cerate as a radiopaque component of hydraulic endodontic cement Materials (Basel, Switzerland). 2022.01; 15 (284): ( DOI )

Htoo Shwe Sin Thein , Hashimoto Kentaro, Kawashima Nobuyuki, Noda Sonoko, Okiji Takashi. Evaluation of the anti-inflammatory effects of surface-reaction-type pre-reacted glass-ionomer filler containing root canal sealer in lipopolysaccharide-stimulated RAW264.7 macrophages Dental Materials Journal. 2022.01; 41 (1): 150-158. ( ichushi )

Adel S, Hashimoto K, Kawashima N, Wada T, Uo M, Okiji T. Biocompatibility and pro-mineralization effect of tristrontium aluminate cement for endodontic use Journal of Dental Sciences. 2022.01; ( DOI )

Orikasa S, Kawashima N, Tazawa K, Hashimoto K, Sunada-Nara K, Noda S, Fujii M, Akiyama T, Okiji T. Hypoxia-inducible factor 1α induces osteo/odontoblast differentiation of human dental pulp stem cells via Wnt/β-catenin transcriptional cofactor BCL9. Scientific reports. 2022.01; 12 (1): 682. ( PubMed, DOI )

Okada Y, Kawashima N, Nod S, Murano H, Han P, Hashimoto K, Kaneko T, Okiji T. VEGFA promotes odonto/osteoblastic differentiation in dental pulp stem cells via ERK/p38 signaling Journal of Dental Sciences. 2022; in press ( DOI )

Dumrongvute K, Adel S, Wada T, Kawashima N, Piyachon C, Watanabe H, Kurabayashi T, Okiji T, Uo M. Distrontium Cerate as a Radiopaque Component of Hydraulic Endodontic Cement. Materials (Basel, Switzerland). 2021.12; 15 (1): ( PubMed, DOI )

Sunada-Nara Keisuke, Kawashima Nobuyuki, Okiji Takashi. Micro-endodontic management of a fused mandibular molar with rare anatomical features: a case report Micro: the International Journal of Microdentistry. 2021.11; 12 (2): 70-76. ( ichushi )

Zaw ZCT, Kawashima N, Kaneko T, Okii T. Angiogenesis during coronal pulp regeneration using rat dental pulp cells: neovascularization in rat molars in vivo and proangiogenic dental pulp cell-endothelial cell interactions in vitro Journal of Dental Sciences. 2021.07; in press

Phyo YS, Hashimoto K, Kawashima N, Kuramoto M, Okiji T. Evaluation of the cytocompatibility of methacrylate resin-based root canal sealers with osteoblast-like cells. Dental materials journal. 2021.07; 40 (4): 942-948. ( PubMed, DOI )

Adel S, Wada T, Kawashima N, Abdou A, Watanabe H, Kurabayashi T, Okiji T, Uo M. Preparation and properties of tristrontium aluminate as an alternative component of mineral trioxide aggregate (MTA) cement. Dental materials journal. 2021.01; 40 (1): 184-190. ( PubMed, DOI )

Phyo Y, Hashimoto K, Kawashima N, Kuramoto M, Okiji T. Evaluation of the cytocompatibility of methacrylate resin-based root canal sealers with osteoblast-like cell Dental Materials Journal. 2021;

Thein HSS, Hashimoto K, Kawashima N, Noda S, Okiji T . Evaluation of the anti-inflammatory effects of surface-reaction-type pre-reacted glass-ionomer filler containing root canal sealer in lipopolysaccharide-stimulated RAW264.7 macrophages Dental Materials Journal. 2021;

Kuramoto M, Kawashima N, Tazawa K, Nara K, Fujii M, Noda S, Hashimoto K, Nozaki K, Okiji T. Mineral trioxide aggregate suppresses pro-inflammatory cytokine expression via the calcineurin/nuclear factor of activated T cells/early growth response 2 pathway in lipopolysaccharide-stimulated macrophages. International endodontic journal. 2020.12; 53 (12): 1653-1665. ( PubMed, DOI )

Kawashima N, Hashimoto K, Kuramoto M, Bakhit A, Wakabayashi Y, Okiji T. A Novel Bioactive Endodontic Sealer Containing Surface-Reaction-Type Prereacted Glass-Ionomer Filler Induces Osteoblast Differentiation. Materials (Basel, Switzerland). 2020.10; 13 (20): ( PubMed, DOI )

Tazawa K, Kawashima N, Kuramoto M, Noda S, Fujii M, Nara K, Hashimoto K, Okiji T. Transient Receptor Potential Ankyrin 1 (TRPA1) is Up-Regulated in Response to Lipopolysaccharide via P38/ Mitogen-Activated Protein Kinase (MAPK) in Dental Pulp Cells and Promotes Mineralization. The American journal of pathology. 2020.09; 190 (12): 2417-2426. ( PubMed, DOI )

Fujii M, Kawashima N, Tazawa K, Hashimoto K, Nara K, Noda S, Nagai S, Okiji T. Hypoxia-inducible factor 1α promotes interleukin 1β and tumour necrosis factor α expression in lipopolysaccharide-stimulated human dental pulp cells. International endodontic journal. 2020.05; 53 (5): 636-646. ( PubMed, DOI )

Bakhit A, Kawashima N, Hashimoto K, Noda S, Nara K, Kuramoto M, Tazawa K, Okiji T. Author Correction: Strontium ranelate promotes odonto-/osteogenic differentiation/mineralization of dental papillae cells in vitro and mineralized tissue formation of the dental pulp in vivo. Scientific reports. 2020.05; 10 (1): 8375. ( PubMed, DOI )

Nara K, Kawashima N, Noda S, Fujii M, Hashimoto K, Tazawa K, Okiji T. Anti-inflammatory roles of microRNA 21 in lipopolysaccharide-stimulated human dental pulp cells. Journal of Cellular Physiology.. 2019.11; 234 (11): 21331-21341. ( PubMed, DOI )

Fujii M, Kawashima N, Tazawa K, Hashimoto K, Nara K, Noda S, Kuramoto M, Orikasa S, Nagai S, Okiji T . HIF1α inhibits LPS-mediated induction of IL-6 synthesis via SOCS3-dependent CEBPβ suppression in human dental pulp cells Biochemical and Biophysical Research Communications . 2019.11; 522 (2): 308-314. ( PubMed, DOI )

Noda S, Kawashima N, Yamamoto M, Hashimoto K, Nara K, Sekiya I, Okiji T. Effect of cell culture density on dental pulp-derived mesenchymal stem cells with reference to osteogenic differentiation. Scientific Reports. 2019.04; 9 (1): 5430. ( PubMed, DOI )

Hirai K, Furusho H, Kawashima N, Xu S, de Beer MC, Battaglino R, Van Dyke T, Stashenko P, Sasaki H. Serum amyloid A contributes to chronic apical periodontitis via TLR2 and TLR4 Journal of Dental Research. 2019.01; 98 (1): 117-125. ( PubMed, DOI )

Bakhit A, Kawashima N, Hashimoto K, , Noda S, Nara K, , Kuramoto M, Tazawa K, Okiji T. Strontium ranelate promotes odonto-/osteogenic differentiation/mineralization of dental papillae cells in vitro and mineralized tissue formation of the dental pulp in vivo. Scientific Reports. 2018.06; ( PubMed, DOI )

Hashimoto K, Kawashima N, Ichinose S, Nara K, Noda S, Okiji T. EDTA Treatment for Sodium Hypochlorite-treated Dentin Recovers Disturbed Attachment and Induces Differentiation of Mouse Dental Papilla Cells. Journal of Endodontics. 2018.02; 44 (2): 256-262. ( PubMed, DOI )

バキト・アラムッヂン , 川島 伸之, 橋本 健太郎, 野田 園子, 奈良 圭介, 興地 隆史. ラネル酸ストロンチウムによるマウス歯乳頭細胞の増殖および石灰化はカルシウム感知受容体を介して誘導される 特定非営利活動法人日本歯科保存学会学術大会プログラムおよび講演抄録集. 2017.10; 147回 63. ( ichushi )

Kawashima N, Noda S, Yamamoto M, Okiji T. Properties of dental pulp-derived mesenchymal stem cells and the effects of culture conditions. Journal of Endodontics. 2017.09; 43 (9S): S31-S34. ( PubMed, DOI )

Kawashima Nobuyuki, Okiji Takashi. 象牙芽細胞　象牙質-歯髄複合体における特殊な硬組織形成細胞(Odontoblasts: Specialized hard-tissue-forming cells in the dentin-pulp complex) Congenital Anomalies. 2017.07; 56 (4): 144-153. ( ichushi )

Kento Tazawa, Hideharu Ikeda, Nobuyuki Kawashima, Takashi Okiji. Transient receptor potential melastatin (TRPM) 8 is expressed in freshly isolated native human odontoblasts. Archives of Oral Biology. 2016.12; 75 55-61. ( PubMed, DOI )

Kawashima N, Okiji T. Odontoblasts: Specialized hard-tissue-forming cells in the dentin-pulp complex Congenital Anomalies (Kyoto). 2016.07; 56 (4): 144-153. ( PubMed, DOI )

Suzuki N, Takimoto K, Kawashima N. Cathepsin K inhibitor regulates inflammation and bone destruction in experimentally induced rat periapical lesions Journal of Endodontics. 2015.09; 41 (9): 1474-1479. ( PubMed, DOI )

Zhou M, Kawashima N, Suzuki N, Yamamoto M, Ohnishi O, Katsube K, Tanabe H, Kudo A, Saito M, Suda H. Periostin is a negative regulator of mineralization in the dental pulp tissue Odontology. 2015.05; 103 (2): 152-159. ( PubMed, DOI )

Takimoto K, Kawashima N, Suzuki N, Koizumi Y, Yamamoto M, Nakashima M, Suda Heaki. Down-regulation of inflammatory mediator synthesis and infiltration of inflammatory cells by MMP-3 in experimentally-induced rat pulpitis Journal of Endodontics. 2014.09; 40 (9): 1404-1409. ( DOI )

Yamamoto M, Kawashima N, Takashino N, Koizumi Y, Takimoto K, Suzuki N, Saito M, Suda H. Three-dimensional spheroid culture promotes odonto/osteoblastic differentiation of dental pulp cells Archives of Oral Biology. 2014.03; 59 (3): 310-317. ( DOI )

Wei S, Kawashima N, Suzuki N, Xu J, Takahashi S, Zhou M, Koizumi Y, Suda H. Kinetics of Th17-related cytokine expression in experimentally induced rat periapical lesions Australian Endodontic Journal. 2013.12; 39 (3): 164-170. ( DOI )

11. Yoshida T, Iwata T, Umemoto T, Shiratsuchi Y, Kawashima N, Sugiyama T, Yamato M and Okano T. Promotion of mouse ameloblast proliferation by Lgr5 mediated integrin signaling Journal of Cellular Biochemistry. 2013.09; 114 (9): 2138-2147. ( DOI )

Koizumi Yu, Kawashima Nobuyuki, Yamamoto Mioko, Takimoto Koyo, Zhou Mengyu, Suzuki Noriyuki, Saito Masahiro, Harada Hidemitsu, Suda Hideaki. Wnt11 expression in rat dental pulp and promotional effects of Wnt signaling on odontoblast differentiation Congenital Anomalies. 2013.09; 53 (3): 101-108. ( DOI )

Yoshida T., Kumashiro Y., Iwata T., Ishihara J., Umemoto T., Shiratsuchi Y., Kawashima N., Sugiyama T., Yamato M., Okano T.. Requirement of integrin beta 3 for iron transportation during enamel formation Journal of Dental Research. 2012.12; 91 (12): 1154-1159. ( DOI )

Kawashima N. Characterisation of dental pulp stem cells: A new horizon for tissue regeneration? Archives of Oral Biology. 2012.11; 57 (11): 1439-1458. ( DOI )

Xu J, Kawashima N, Fujiwara N, Harada H, Ota MS, Suda H. Promotional effects of vasoactive intestinal peptide on the development of rodent Hertwig's epithelial root sheath Congenital Anomalies. 2012.09; 52 (3 SI): 162-167. ( PubMed, DOI )

Sun H, Yang J, Kawashima N, Li Y, Zhang W, Wang P. A brief comparison of curricula at dental schools in China and Japan Journal of Dental Education. 2012.06; 76 (6): 765-773.

Bolortuya Gombo, Ebihara Arata, Ichinose Shizuko, Watanabe Satoshi, Anjo Tomoo, Kokuzawa Chizuko, Saegusa Hidetoshi, Kawashima Nobuyuki, Suda Hideaki. Effects of Dentin Surface Modifications Treated with Er:YAG and Nd:YAG Laser Irradiation on Fibroblast Cell Adhesion PHOTOMEDICINE AND LASER SURGERY. 2012.02; 30 (2): 63-70. ( DOI )

Bolortuya G., Ebihara A., Ichinose S., Watanabe S., Anjo T., Kokuzawa C., Saegusa H., Kawashima N., Suda H.. Initial fibroblast attachment to Erbium:YAG laser-irradiated dentine INTERNATIONAL ENDODONTIC JOURNAL. 2011.12; 44 (12): 1134-1144. ( DOI )

Wang HG., Kawashima N., Iwata T., Xu J., Takahashi S., Sugiyama T., Suda H.. MEPE activated by furin promotes pulpal cell adhesion Journal of Dental Research. 2011.04; 90 (4): 529-534. ( DOI )

Wang S, Kawashima N, Sakamoto K, Katsube K, Umezawa A, Suda H. Osteogenic differentiation of mouse mesenchymal progenitor cell, Kusa-A1 is promoted by mammalian transcriptional repressor Rbpj Biochemical and Biophysical Research Communications. 2010.09; 400 (1): 39-45. ( PubMed, DOI )

Sun H, Kawashima N, Xu J, Takahashi S, Suda H. Expression of Notch signalling-related genes in normal and differentiating rat dental pulp cells Australian Endodontic Journal. 2010.08; 36 (2): 54-58. ( PubMed, DOI )

Wang H, Kawashima N, Iwata T, Xu J, Takahashi S, Sugiyama T, Suda H. Differentiation of odontoblasts is negatively regulated by MEPE via its C-terminal fragment. Biochemical and Biophysical Research Communications. 2010.07; 398 (3): 406-412. ( PubMed, DOI )

Kawashima N, Wadachi R, Suda H, Yeng T, Parashos P.. Root canal medicaments. International Dental Journal. 2009.02; 59 (1): 5-11. ( PubMed )

Kabasawa Y., Nagumo K., Takeda Y., Kawashima N., Okada N., Omura K., Yamaguchi A., Katsube K.. Amelogenin positive cells scattered in the interstitial component of odontogenic fibromas Journal of Clinical Pathology. 2008.07; 61 (7): 851-855. ( PubMed, DOI )

Sasaki H, Suzuki N, Kent R, Kawashima N, Takeda J, Stashenko P. T cell response mediated by myeloid cell-derived IL-12 is responsible for Porphyromonas gingivalis-induced periodontitis in IL-10-deficient mice. Journal of Immunology. 2008.05; 180 (9): 6193-6198. ( PubMed )

Kawashima N, Suzuki N, Yang G, Ohi C, Okuhara S, Nakano-Kawanishi H, Suda H. Kinetics of RANKL, RANK and OPG expressions in experimentally induced rat periapical lesions Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 2007.05; 103 (5): 707-711. ( PubMed, DOI )

Satomi Takahashi, Nobuyuki Kawashima, Kei Sakamoto, Akira Nakata, Takashi Kameda, Toshihiro Sugiyama, Ken-ichi Katsube, Hideaki Suda. Differentiation of an ameloblast-lineage cell line (ALC) is induced by Sonic hedgehog signaling. Biochem. Biophys. Res. Commun.. 2007.02; 353 (2): 405-411. ( PubMed, DOI )

Guangyan Yang, Nobuyuki Kawashima, Tomoatsu Kaneko, Noriyuki Suzuki, Takashi Okiji, Hideaki Suda. Kinetic study of immunohistochemical colocalization of antigen-presenting cells and nerve fibers in rat periapical lesions. J Endod. 2007.02; 33 (2): 132-136. ( PubMed, DOI )

Nobuyuki Kawashima, Indra Wongyaofa, Noriyuki Suzuki, Hiromi Nakano Kawanishi, Hideaki Suda. NK and NKT cells in the rat dental pulp tissues. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006.10; 102 (4): 558-563. ( PubMed, DOI )

Jian Zhang, Nobuyuki Kawashima, Hideaki Suda, Yukiko Nakano, Yoshiro Takano, Miyuki Azuma. The existence of CD11c+ sentinel and F4/80+ interstitial dendritic cells in dental pulp and their dynamics and functional properties. Int. Immunol.. 2006.09; 18 (9): 1375-1384. ( PubMed, DOI )

N Kawashima, H Nakano-Kawanishi, N Suzuki, M Takagi, H Suda. Effect of NOS inhibitor on cytokine and COX2 expression in rat pulpitis. J. Dent. Res.. 2005.08; 84 (8): 762-767. ( PubMed )

Nobuyuki Kawashima, Kentaro Shindo, Kei Sakamoto, Hisatomo Kondo, Akihiro Umezawa, Shohei Kasugai, Bernard Perbal, Hideaki Suda, Minoru Takagi, Ken-ichi Katsube. Molecular and cell biological properties of mouse osteogenic mesenchymal progenitor cells, Kusa. J. Bone Miner. Metab.. 2005; 23 (2): 123-133. ( PubMed, DOI )

Kawanishi HK, Kawashima N, Suzuki N, Suda H, Takagi M. Effects of an inducible nitric oxide synthase inhibitor on experimentally induced rat EUROPEAN JOURNAL OF ORAL SCIENCES. 2004.08; 112 (4): 332-337. ( DOI )

Hajime Sasaki, Khaled Balto, Nobuyuki Kawashima, Jean Eastcott, Katsuaki Hoshino, Shizuo Akira, Philip Stashenko. Gamma interferon (IFN-gamma) and IFN-gamma-inducing cytokines interleukin-12 (IL-12) and IL-18 do not augment infection-stimulated bone resorption in vivo. Clin. Diagn. Lab. Immunol.. 2004.01; 11 (1): 106-110. ( PubMed )

Kentaro Shindo, Nobuyuki Kawashima, Kei Sakamoto, Akira Yamaguchi, Akihiro Umezawa, Minoru Takagi, Ken-ichi Katsube, Hideaki Suda. Osteogenic differentiation of the mesenchymal progenitor cells, Kusa is suppressed by Notch signaling. Exp. Cell Res.. 2003.11; 290 (2): 370-380. ( PubMed )

N Kawashima, P Stashenko. Expression of bone-resorptive and regulatory cytokines in murine periapical inflammation. Arch. Oral Biol.. 1999.01; 44 (1): 55-66. ( PubMed )

A M Kamal, T Okiji, N Kawashima, H Suda. Defense responses of dentin/pulp complex to experimentally induced caries in rat molars: an immunohistochemical study on kinetics of pulpal Ia antigen-expressing cells and macrophages. J Endod. 1997.02; 23 (2): 115-120. ( PubMed )

N Kawashima, T Okiji, T Kosaka, H Suda. Kinetics of macrophages and lymphoid cells during the development of experimentally induced periapical lesions in rat molars: a quantitative immunohistochemical study. J Endod. 1996.06; 22 (6): 311-316. ( PubMed, DOI )

T Okiji, T Kosaka, A M Kamal, N Kawashima, H Suda. Age-related changes in the immunoreactivity of the monocyte/macrophage system in rat molar pulp. Arch. Oral Biol.. 1996.05; 41 (5): 453-460. ( PubMed )

T Okiji, N Kawashima, T Kosaka, C Kobayashi, H Suda. Distribution of Ia antigen-expressing nonlymphoid cells in various stages of induced periapical lesions in rat molars. J Endod. 1994.01; 20 (1): 27-31. ( PubMed )

T Okiji, I Morita, N Kawashima, T Kosaka, H Suda, S Murota. Immunohistochemical detection of prostaglandin I2 synthase in various calcified tissue-forming cells in rat. Arch. Oral Biol.. 1993.01; 38 (1): 31-36. ( PubMed )

T Okiji, N Kawashima, T Kosaka, A Matsumoto, C Kobayashi, H Suda. An immunohistochemical study of the distribution of immunocompetent cells, especially macrophages and Ia antigen-expressing cells of heterogeneous populations, in normal rat molar pulp. J. Dent. Res.. 1992.05; 71 (5): 1196-1202. ( PubMed )

Wang S, Kawashima N, Yu Z, Okiji T. MicroRNA-27a downregulates proinflammatory cytokines expression in LPS-stimulated human pulp cells. 第88回口腔病学会学術大会 2023.12.01

ラット臼歯歯髄へのMO貼付に伴う視床におけるSostdc1 mRNA発現の低下. 日本歯科保存学会2023年度秋季学術大会（第159回） 2023.11.11 浜松

大島理紗，川島伸之，興地隆史. Induction of odontoblasts in MTA-applied exposed molar pulp tissues is disturbed in osteopontin knockout mice. The 25th KACD-JSCD Joint-Scientific Meeting 2023.11.04 Seoul, Korea

Nyein Chan Ko , 野田 園子, 岡田 大和, 田澤 健人, 川島 伸之, 興地 隆史. ヒト歯髄幹細胞に対するプレミックスカルシウムシリケート系材料の生体親和性および石灰化促進効果(Biocompatibility and pro-mineralization effects of premixed calcium silicate-based materials on human dental pulp stem cells). 特定非営利活動法人日本歯科保存学会学術大会プログラムおよび講演抄録集 2023.10.01

Kawashima N, Okiji T. Effects of hypoxic condition on mineralization and inflammation in the pulp tissue. Asian Pacific Endodontic Confederation (APEC) 2023.08.25 Taipei, Taiwan

Okada Y, Kawashima N, Okiji T. Endodontic retreatment of a maxillary first molar with multiple iatrogenic complications. Asian Pacific Endodontic Confederation (APEC) 2023.08.25 Taipei, Taiwan

Chunmei R, Tazawa K, Kawashima N, Okiji T. Metformin suppresses pro-inflammatory cytokine expression in LPS-stimulated human dental pulp stem cells. 第44回歯内療法学会学術大会 2023.07.09 東京

Chunmei Ren, Tazawa Kento, Kawashima Nobuyuki, Okiji Takashi. メトホルミンはLPS刺激ヒト歯髄幹細胞における炎症性サイトカイン発現を抑制する(Metformin suppresses pro-inflammatory cytokine expression in LPS-stimulated human dental pulp stem cells). 日本歯内療法学会学術大会プログラム・抄録集 2023.07.01

アルチャウーシュ・アシール , 橋本 健太郎, 川島 伸之, 野崎 浩佑, 興地 隆史. 水硬性ケイ酸カルシウム系歯内療法用材料の抽出物はマウス骨芽細胞のミネラル化を促進する(Extracts from hydraulic calcium silicate-based endodontic materials promoted mineralization in murine osteoblastic cells). 特定非営利活動法人日本歯科保存学会学術大会プログラムおよび講演抄録集 2022.10.01

Alchawoosh A, Hashimoto K, Kawashima N, Okiji T. Anti inflammatory effects of hydraulic calcium silicate based endodontic sealers on lipopolysaccharide stimulated macrophages. 第43回日本歯内療法学会学術大会 2022.07.09

Alchawoosh Aseel, Hashimoto Kentaro, Kawashima Nobuyuki, Okiji Takashi. リポポリサッカライドで刺激したマクロファージに対する水硬性ケイ酸カルシウムを用いた歯内シーラーの抗炎症効果(Anti-inflammatory effects of hydraulic calcium silicate-based endodontic sealers on lipopolysaccharide-stimulated macrophages). 日本歯内療法学会学術大会プログラム・抄録集 2022.07.01

Yu Z, Sunada-Nara K, Kawashima N, Kieu QT, Han P, Okiji T.. MicroRNA-27a upregulates osteoblastic markers-expression in human dental pulp cells.. The 100th General Session & Exhibition of the IADR 2022.06.22 Virtual Meeting

Thoai　KQ, Tazawa K, Kawashima N, Noda S, Fujii M, Sunada-Nara K, Hashimoto K, Han P & Okiji T. LYVE-1+ M2-macrophages: identification in dental-pulp and their pro-angiogenic activity in-vitro. IADR/APR General Session & Exhibition 2022.06.20 VIRTUAL EXPERIENCE

Wang S, Sunada-nara K, Kawashima N, Han P, Thoai KW, Yu Z, Okiji T. MicroRNA-27a downregulates proinflammatory cytokines expression in LPS-stimulated human dental pulp cells. 2022 IADR/APR General Session & Exhibition 2022.06.20 VIRTUAL EXPERIENCE

Han P, Sunada-Nara K, Kawashima N, Wang S, Thoai KQ, Yu Z, Okiji T . MicroRNA-146b suppresses proinflammatory mediators synthesis in lipopolysaccharide-stimulated dental pulp cells. 2022 IADR/APR General Session & Exhibition 2022.06.20 VIRTUAL EXPERIENCE

Kawashima N.. MTA: Anti-inflammatory Actions & Insight of its Mechanisms Strontium Ranelate: A Candidate of new Pulp Capping Material. 5th International Symposium of Iranian Association of Endodontists 2022.03.02 Zoom

Adel Sherif, Hashimoto Kentaro, Kawashima Nobuyuki, Wada Takahiro, Uo Motohiro, Okiji Takashi. アルミン酸三ストロンチウムセメントの生体適合性と骨化誘導作用(Biocompatibility and pro-mineralization effect of tristrontium aluminate cement). 口腔病学会雑誌 2022.03.01

Adel S, Hashimoto K, Kawashima N, Wada T, Uo M, Okiji T. Biocompatibility and pro-mineralization effect of tristrontium aluminate cement. 第８６回口腔病学会 2021.12.04

Okada Y, Kawashima N, Noda S, Murano H, Zaw ZCT, Han P, Hashimoto K, Okiji T. Vascular endothelial growth factor promotes migration and osteo/odontoblastic differentiation of SHEDs via ERK signaling. The International Scientific Meeting of 30th Anniversary of Korean Academy of Endodontics & the 19th JEA-KAE Joint Scientific Meeting 2021.10.29 Seoul, Korea

韓沛豊、砂田(奈良)圭介、川島伸之、 Wang S, Thoai KQ, 興地隆史. LPSで刺激されたヒト歯髄細胞におけるMicroRNA146bの抗炎症作用. 日本歯科保存学会2021年度秋季学術大会(155回) 2021.10.28 Web開催

韓 沛豊, 砂田 圭介[奈良], 川島 伸之, Wang Shihan, Kieu Quoc Thoai, 興地 隆史. LPSで刺激されたヒト歯髄細胞におけるMicroRNA146bの抗炎症作用(Anti-inflammatory Effects of MicroRNA146b on Lipopolysaccharide-stimulated Human Dental Pulp Cells). 特定非営利活動法人日本歯科保存学会学術大会プログラムおよび講演抄録集 2021.10.01

Kawashima N, Kuramoto M, Okiji T. Anti-inflammatory action of mineral trioxide aggregate; a new insight. Asian Pacific Endodontic Confederation 2021.09.10 Beirut, Lebanon

Fujii M, Kawashima N, Nara K, Noda S, Hashimoto K, Okiji T.. Hypoxia-induced microRNA-210 regulates inflammatory cytokine expression in lipopolysaccharide-stimulated dental-pulp cells. 2021 IADR/AADR/CADR General Session 2021.07.22 Virtual Meeting

Sunada-Nara K, Kawashima N, Fujii M, Noda S, Hashimoto K, Okiji T. MicroRNA -146b downregulates proinflammatory cytokine expression in LPS-stimulated human pulp cells.. 2021 IADR/AADR/CADR General Session 2021.07.22 Virtual Meeting

Htoo Shwe Sin Thein , Hashimoto Kentaro, Noda Sonoko, Kawashima Nobuyuki, Okiji Takashi. リポポリサッカライド刺激マクロファージにおいて歯根管密封剤含有の酸反応性フッ素含有ガラスフィラーは炎症誘導性サイトカインを減少させる(Surface-reaction-type prereacted glass-ionomer filler containing root canal sealer down-regulates pro-inflammatory cytokines in lipopolysaccharide-stimulated macrophages). 特定非営利活動法人日本歯科保存学会学術大会プログラムおよび講演抄録集 2021.05.01

折笠紫音. 低酸素誘導因子1αはWnt/β-catenin転写補助因子BCL9を介してヒト歯髄幹細胞の骨芽・象牙芽細胞分化を誘導する. 令和2年度バランスユニット若手研究者ワークショップ 2021.03.09 Web開催

Thoai KQ, Tazawa K, Kawashima N, Nara K, Fujii M, Noda S, Hashimoto K, Okiji T. Lyve-1+ pulpal macrophages: M2-polarization and response to cavity preparation. 第68回JADR総会・学術大会 2020.11.07 東京　Web開催

Kieu Quoc T, Tazawa K, Kawashima N, Nara K, Fujii M, Noda S, Hashimoto K, Okiji T. Lyve-1+ Pulpal Macrophages: M2-polarization and Response to Cavity Preparation. The 68th Annual Meeting of Japanese Assosiation for Dental Research 2020.11.07 Vertual Meeting

Tazawa Kento, Kawashima Nobuyuki, Kuramoto Masashi, Nara Keisuke, Fujii Mayuko, Noda Sonoko, Hashimoto Kentaro, Okiji Takashi. TRPA1 is upregulated in response to LPS via p38/MAPK and promotes mineralization in dental pulp cells. 2019年度バランスユニット若手ワークショップ 2020.02.07 Tokyo

Mayuko F, Nobuyuki K, Shion O, Sonoko N, Keisuke N, Kentaro H, Kento T, Shigenori N, Takashi O. HIF1a inhibits LPS-mediated induction of IL-6 synthesis via SOCS3-dependent CEBPb suppression in human dental pulp cells. The 21th KACD-JSCD Joint Scientific Meeting 2019.11.09 Soul, South korea

Orikasa S, Kawashima N, Fujii M, Yamamoto M, Hashimoto K, Tazawa K, Okiji T. Hypoxic condition induces hypoxia-inducible factor 1α and upregulates Wnt/β-catenin transcriptional cofactors, Bcl9 and Bcl9l, in mouse dental papillae cells. The 21st KACD-JSCD Joint Scientific Meeting 2019.11.09 Seoul, Korea

倉本将司，川島伸之，田澤建人，奈良圭介，藤井真由子，野田園子，橋本健太郎，興地隆史. MTAはマクロファージからの炎症性メディエーター産生をcalcineurin/NFATシグナルを介して抑制する. 日本歯科保存学会２０１９年度秋季学術大会（第１５１回） 2019.11.08 博多

Kawashima N, Kuramoto K, Bakhit A, Hashimoto K, Okiji T. Osteoblast differentiation induced by a prototype S-PRG filler-containing endodontic sealer. IADR/AADR/CADR General Session & Exhibition 2018.07.25 London, England

Noda S, Kawashima N, Hashimoto K, Nara K, Kuramoto M, Tazawa K, Okiji T. In Vivo Mineralization and In Vitro Differentiation of Dense-Cultured DPSCs. 96th General Session & Exhibition of the IADR 2018.07.25 London, England

Kawashima N, Noda S, Yamamoto M, Okiji T. Hard-tissue forming properties of dental pulp derived-mesenchymal stem cells. 2017 Faculty Annual Scientific Meeting of Hong Kong University 2017.12.14 Prince Philip Dental Hospital, Hong Kong University, Hong Kong

ラネル酸ストロンチウムによるマウス歯乳頭細胞の増殖および石灰化はカルシウム感知受容体を介して誘導される. 第147回日本歯科保存学会2017年度秋季学術大会 2017.10.27 盛岡

藤井真由子, 川島伸之, 興地隆史. ヒト歯髄細胞における炎症性メディエーター産生制御におけるHIF1aの役割. 第59回歯科基礎医学会学術大会 2017.09.16 塩尻

Noda S, Kawashima N, Hashimoto K, Aramaki O, Yamamoto M, Okiji T. Dense culture conditions induced human dental pulp stem cell differentiation. 95th Generel Session & Exhibition of the IADR 2017.03.22 San Francisco, CA

Kawashima N, Noda S, Hashimoto K, Saito M, Okiji T. Meis2 induces odonto-/osteoblastic differentiation and mineralization. 95th General Session & Exhibition of the IADR 2017.03.22 San Francisco, CA

Kawashima N, Hashimoto K, Okiji T. Rescue of mouse dental papillae cell-attachment to sodium hypochlorite-treated dentin disks by EDTA treatment. The 49th Scientific Meeting of Korean Academy of Endodontics 2016.11.19 Seoul, Korea

Nara K, Kawashima N, Noda S, Hashimoto K, Okiji T. MicroRNA21 down-regulates the expression of inflammatory mediators in LPS-stimulated human dental pulp cells via an NF-κB dependent mechanism. 2016 Autumn Scientific Meeting (the 146th) and Joint Scientific Meeting of KACD-JACD (the 18th) 2016.10.23 Seoul, Korea

Fujii M, Kawashima N, Okiji T. Induction of HIF1a in human dental pulp cells by lipopolysaccharide. 第58回歯科基礎医学会学術大会 2016.08.24 札幌,北海道

Nara K, Kawashima N, Noda S, Hashimoto K, Bakhit A, Okiji T. Increase of miR21 expression in dental pulp cells and tissues in response to LPS stimulation. IADR Pulp Biology and Regeneration Group Satellite Symposium 2016 2016.06.28 Nagoya, Japan

Noda S, Kawashima N, Hashimoto K, Aramaki O, Yamamoto M, Okiji T. Effects of confluent culture condition on dental pulp stem cell surface markers, proliferation, gene expression. IADR Pulp Biology and Regeneration Group Satellite Symposium 2016 2016.06.28 Nagoya, Japan

Hashimoto K, Kawashima N, Nara K, Noda S, Saito M, Okiji T. Recovery effects of EDTA treatment on the attachment and differentiation of mouse dental pulp cells cultured on NaOCl-treated dentin. IADR Pulp Biology and Regeneration Group Satellite Symposium 2016 2016.06.28 Nagoya, Japan

Kawashima N, Noda S, Hashimoto K, Yamamoto M, Okiji T. Properties of dental pulp derived-mesenchymal stem cells and effects of culture conditions. IADR Pulp Biology and Regeneration Group Satellite Symposium 2016 2016.06.26 Nagoya

Bakhit A, Kawashima N, Yamamoto M, Hashimoto K, Noda S, Nara K, Okiji T. Effects of strontium ranelate on the mouse dental papillae cells (MDPs). IADR Pulp Biology and Regeneration Group Satellite Symposium 2016 2016.06.22 Nagoya

Tazawa K, Ikeda H, Kawashima N, Ozawa M, Suda H, Okiji T. Expression of TRPM8 in freshly isolated human odontoblasts.. 94th General Session & Exhibition of the International Association for Dental Research (IADR) 2016.06.22 South Korea

Aramaki O, Kawashima N, Shimada Y, Okiji T, Tagami J . Three-dimensional analysis of Iba1+ macrophages in human dental pulp using whole mount immunostaining. 94th General Session & Exhibition of the IADR 2016.06.22 Seoul, Korea

Bakhit A, Kawashima N, Hashimoto K, Noda S, Nara K, Okiji T. Cytotoxic effects of new calcium silicate-based sealers on an osteoblastic cell line. The 143rd Meeting of the Japanese Society of Conservative Dentisty 2015.11.12 Tokyo

Yamamoto M, Hashimoto K, Bakhit A, Suzuki N, Kawashima N, Okiji T. Effects of short-period three-dimensional (3D) spheroid culture for odonto-/osteoblastic differentiation of dental pulp cells. 17th Biennial ESE Congress 2015.09.19

Kawashima N. Intracanal medicament. The 18th APEC congress 2015.04.08 Amman, Jordan

Hashimoto K, Kawashima N, Bakhit A, Yamamoto M, Koizumi Y, Takahashi S, Ohi C, Suzuki N. ALPase activity of pulp cells on EDTA and NaClO-treated dentin. 93rd General Session and Exhibition of the IADR 2015.03.11 Boston, MA

Kawashima N, Hashimoto K, Bakhit A, Yamamoto M, Koizumi Y, Takahashi S, Ohi C, Suzuki N. Mineralizing properties of gingiva-derived mesenchymal stem cells cultured in 3D-condition. 93rd General Session and Exhibition of the IADR 2015.03.11 Boston, MA

Kawashima N, Suzuki N. Bone tissue regeneration using the spheroid cultured dental pulp stem cells. AAE Annual Session 2014 2014.04.30 Washington DC

Kawashima N. Regenerative endodontics-induction of bone and dental pulp tissue from dental pulp. International symposium of molecular mechanism in bone and tooth, its clinical implication 2014.01.20 Tokyo

Yamamoto M, Kawashima N, Koizumi Y, Takimoto K, Onishi K, Suzuki N, Katsube K, Saito M, Harada H, Suda H. Spheroid culture induces odonto-/osteoblastic differentiation of dental pulp cells through integrin signaling. 16th ESE (European Society of Endodontology) Biennial Congress 2013.09.12 Lisbon

Kawashima N, Mengu Z, Yamamoto M, Koizumi Y, Takimoto K, Onishi K, Suzuki N, Katsube K, Saito M, Harada H, Suda H. Periostin: a negative regulator of mineralization in the dental pulp tissue. 16th ESE (European Society of Endodontology) Biennial Congress 2013.09.12 Lisbon

Kawashima N.. Establishment of the isolation method for dental pulp stem cells and induction of dental pulp tissue and/or bone tissue from dental pulp stem cells. 平成25年度 (2013) 「歯・骨関連疾患のグローバル研究センター」国際総合プレゼンテーション 2013.06.04 東京

Henmi K, Kawashima N, Suda H. Effects of Nano-bubbles on Enterococcus faecalis - Transmission Electron Microscopy Investigation. The 9th World Endodontic Conference 2013.05.23 Tokyo

Suzuki N, Kawashima N, Suda H. Suppressive Regulation of Bone Destruction in Rat Periapical Lesions by Cathepsin K Inhibitor. The 9th World Endodontic Conference 2013.05.23 Tokyo

Takimoto K, Kawashima N, Suda H. Down-regulation of Inflammatory Mediator Synthesis and Infiltration of Immunocompetent Cells in Rat Experimental Pulpitis by MMP-3. The 9th World Endodontic Conference 2013.05.23

Yamamoto M, Kawashima N, Suda H. 3-D Spheroid Culture Method Promotes Odonto-/Osteo-blastic Differentiation of Dental Pulp Cells. The 9th World Endodontic Conference 2013.05.23 Tokyo

Kawashima N, Suda H. Importance of Differential Diagnosis in Keratocystic Odontogenic Tumor. The 9th World Endodontic Conference 2013.05.23 Tokyo

Kawashima N, Yamamoto M, Takashino N, Takimoto K, Koizumi Y, Suzuki N, Suda H. Stem Cell Marker Expression in the 3-D Spheroid Cultured Human Dental Pulp Stem Cells. The 140th Scientific meeting of KACD (Korean Academy of Conservative Dentistry) 2013.04.20 Gyeongju

2. Kawashima N, Koizumi Y, Yamamoto M, Takimoto K, Zhou M, Suzuki N, Saito M, Harada H, Suda H. Promoting effects of Wnt signaling on odontoblast differentiation. Asian Pacific Endodontic Conference 2013.03.23 Seoul

3. Aramaki O, Kawashima N, Shimada Y, Suzuki N, Otsuki M, Suda H, Tagami J. Identification of several subpopulations of DCs in rodent dental pulp. 91st General Session & Exhibition of the IADR 2013.03.20

Kawashima N, Suzuki N, Suda H. Mechanisms of Bone Destruction in the Periapical Lesions and Its Regulation. The 16th Scientific Meeting of Asian Pacific Endodontic Confederation 2011.04.21 Shiraz, Iran

Kawashima N. Notch signaling and the osteoblast and odontoblast differentiation. 2008.04.15 Seoul

Notch signaling in the dental pulp, COE symposium. International Symposium on Molecular Destruction and Reconstruction of the Dentin/Pulp Complex and Its Surrounding Tissues 2007.03.05 Tokyo

Kawashima N. Nitric oxide and pulpal inflammation. Dentin Pulp Complex Symposium 2005.09.18 Düsseldorf

Kawashima N.. Osteogenic Properties of the Murine Bone Marrow Stroma-derived Cell Lines: Effects of Notch signaling on the osteogenic differentiation of Kusa-A1. The Forsyth Institute Meeting 2005.09.18