Personnel Information

写真a

KAWASHIMA Nobuyuki


Job title

Junior Associate Professor

Laboratory Address

Pulp Biology and Endodontics Graduate School of Medical and Dental Sciences Tokyo Medical and Dental University 1-5-45 Yushima Bunkyo-ku Tokyo 113-8549 Japan

Laboratory Phone number

+81-3-5803-5495

Laboratory Fax number

+81-3-5803-5494

Graduating School 【 display / non-display

  • Niigata University, Faculty of Dentistry, 1986.03, Graduated

Graduate School 【 display / non-display

  • Tokyo Medical and Dental University, Graduate School, Division of Dental Research, Doctor's Course, 1991.03, Completed

Campus Career 【 display / non-display

  • 2008.04
    -
    2017.09
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Oral Health Sciences, Pulp Biology and Endodontics, Assistant Professor
  • 2017.10
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Oral Health Sciences, Pulp Biology and Endodontics, Junior Associate Professor
  • 2005.12
    -
    2008.03
    , Project Associate Professor
  • 2003.10
    -
    2005.11
    , Project Junior Associate Professor
  • 1995.04
    -
    2003.09
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Oral Health Sciences, Pulp Biology and Endodontics, Assistant Professor

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External Career 【 display / non-display

  • 1991.04
    -
    1992.03
    , Dental Resident
  • 1994.04
    -
    1995.03
    , Dental Resident
  • 1995.04
    -
    2003.09
    , Assistant Professor
  • 2003.10
    -
    2005.11
    , Project Junior Associate Professor
  • 2005.12
    -
    2008.03
    , Project Associate Professor

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Research Areas 【 display / non-display

  • Conservative dentistry

Qualification Acquired 【 display / non-display

  • Dentist

 

Published Papers & Misc 【 display / non-display

  • Kawashima N, Hashimoto K, Kuramoto M, Bakhit A, Wakabayashi Y, Okiji T. A Novel Bioactive Endodontic Sealer Containing Surface-Reaction-Type Prereacted Glass-Ionomer Filler Induces Osteoblast Differentiation. Materials (Basel, Switzerland). 2020.10; 13 (20): ( PubMed, DOI )

  • Tazawa K, Kawashima N, Kuramoto M, Noda S, Fujii M, Nara K, Hashimoto K, Okiji T. Transient Receptor Potential Ankyrin 1 (TRPA1) is Up-Regulated in Response to Lipopolysaccharide via P38/ Mitogen-Activated Protein Kinase (MAPK) in Dental Pulp Cells and Promotes Mineralization. The American journal of pathology. 2020.09; ( PubMed, DOI )

  • Kuramoto M, Kawashima N, Tazawa K, Nara K, Fujii M, Noda S, Hashimoto K, Nozaki K, Okiji T. Mineral trioxide aggregate suppresses pro-inflammatory cytokine expression via the calcineurin/nuclear factor of activated T cells/early growth response 2 pathway in lipopolysaccharide-stimulated macrophages. International endodontic journal. 2020.08; ( PubMed, DOI )

  • Fujii M, Kawashima N, Tazawa K, Hashimoto K, Nara K, Noda S, Nagai S, Okiji T.. Hypoxia-inducible factor 1α promotes interleukin 1β and tumour necrosis factor α expression in lipopolysaccharide-stimulated human dental pulp cells. International Endodontic Journal. 2020.01; ( DOI )

  • Nara K, Kawashima N, Noda S, Fujii M, Hashimoto K, Tazawa K, Okiji T. Anti-inflammatory roles of microRNA 21 in lipopolysaccharide-stimulated human dental pulp cells. Journal of Cellular Physiology.. 2019.11; 234 (11): 21331-21341. ( PubMed, DOI )

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Books etc 【 display / non-display

  • Kawashima N, Suda H. Essential Endodontology. Oxford, Blackwell Publishing, 2008 Pathological aspects of pulpal and periapical inflammations (ISBN : 978-14051-4976-1)

Conference Activities & Talks 【 display / non-display

  • Thoai KQ, Tazawa K, Kawashima N, Nara K, Fujii M, Noda S, Hashimoto K, Okiji T. Lyve-1+ pulpal macrophages: M2-polarization and response to cavity preparation. 第68回JADR総会・学術大会 2020.11.07 東京 Zoom

  • Kieu Quoc T, Tazawa K, Kawashima N, Nara K, Fujii M, Noda S, Hashimoto K, Okiji T. Lyve-1+ Pulpal Macrophages: M2-polarization and Response to Cavity Preparation. The 68th Annual Meeting of Japanese Assosiation for Dental Research 2020.11.07 Vertual Meeting

  • Orikasa S, Kawashima N, Fujii M, Yamamoto M, Hashimoto K, Tazawa K, Okiji T. Hypoxia-inducible factor 1α induces osteo-/odontoblast differentiation of mouse dental papillae cells via Bcl9 and Bcl9l, Wnt/β-catenin transcriptional cofactors.. 2020.02.07 Tokyo

  • Tazawa Kento, Kawashima Nobuyuki, Kuramoto Masashi, Nara Keisuke, Fujii Mayuko, Noda Sonoko, Hashimoto Kentaro, Okiji Takashi. TRPA1 is upregulated in response to LPS via p38/MAPK and promotes mineralization in dental pulp cells. 2019年度バランスユニット若手ワークショップ 2020.02.07 Tokyo

  • Orikasa S, Kawashima N, Fujii M, Yamamoto M, Hashimoto K, Tazawa K, Okiji T. Hypoxic condition induces hypoxia-inducible factor 1α and upregulates Wnt/β-catenin transcriptional cofactors, Bcl9 and Bcl9l, in mouse dental papillae cells. The 21st KACD-JSCD Joint Scientific Meeting 2019.11.09 Seoul, Korea

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Awards & Honors 【 display / non-display

  • Best poster award (Rescue of mouse dental papillae cell-attachment to sodium hypochlorite-treated dentin disks by EDTA treatment, Nobuyuki Kawashima), The 49th Scientific Meeting of Korean Academy of Endodontics,2016.11

 

Performance of duties 【 display / non-display

  • ,2018.08 - Now