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Izuka S, Umezawa N, Komai T, Sugimori Y, Kimura N, Mizoguchi F, Fujieda Y, Ninagawa K, Iwasaki T, Suzuki K, Takeuchi T, Ohmura K, Mimori T, Atsumi T, Kawakami E, Suzuki A, Kochi Y, Yamamoto K, Yasuda S, Okamura T, Ota M, Fujio K: The muscle tissue transcriptome of idiopathic inflammatory myopathy reflects the muscle damage process by monocytes and presence of skin lesions. Arthritis & rheumatology (Hoboken, N.J.). 2024.08; ( PubMed , DOI )
Inamo J, Suzuki A, Ueda MT, Yamaguchi K, Nishida H, Suzuki K, Kaneko Y, Takeuchi T, Hatano H, Ishigaki K, Ishihama Y, Yamamoto K, Kochi Y: Long-read sequencing for 29 immune cell subsets reveals disease-linked isoforms. Nature communications. 2024.05; 15 (1): 4285. ( PubMed , DOI )
Ono C, Kochi Y, Baba Y, Tanaka S: Humoral responses are enhanced by facilitating B cell viability by Fcrl5 overexpression in B cells. International immunology. 2024.05; ( PubMed , DOI )
Oka, A; Hadano, S; Ueda, MT; Nakagawa, S; Komaki, G; Ando, T: Rare CRHR2 and GRM8 variants identified as candidate factors associated with eating disorders in Japanese patients by whole exome sequencing HELIYON. 2024.04; 10 (8): e28643. ( PubMed , DOI )
Okunishi K, Kochi Y, Zhao M, Wang H, Nakagome K, Izumi T: Munc13-4 regulates asthma and obesity in mice by controlling functions of CD11c(+) antigen-presenting cells. Allergy. 2024.03; 79 (7): 1992-1995. ( PubMed , DOI )
Fuseya Y, Kadoba K, Liu X, Suetsugu H, Iwasaki T, Ohmura K, Sumida T, Kochi Y, Morinobu A, Terao C, Iwai K: Attenuation of HOIL-1L ligase activity promotes systemic autoimmune disorders by augmenting linear ubiquitin signaling. JCI insight. 2024.02; 9 (3): ( PubMed , DOI )
Yoriyuki Konno, Keiya Uriu, Takayuki Chikata, Toru Takada, Jun-Ichi Kurita, Mahoko Takahashi Ueda, Saiful Islam, Benjy Jek Yang Tan, Jumpei Ito, Hirofumi Aso, Ryuichi Kumata, Carolyn Williamson, Shingo Iwami, Masafumi Takiguchi, Yoshifumi Nishimura, Eiji Morita, Yorifumi Satou, So Nakagawa, Yoshio Koyanagi, Kei Sato: Two-step evolution of HIV-1 budding system leading to pandemic in the human population. Cell Reports. 2024.02; 43 (2): 113697. ( PubMed , DOI )
Ueda, MT: Retrotransposon-derived transcripts and their functions in immunity and disease GENES & GENETIC SYSTEMS. 2023.12; 98 (6): 305-319. ( PubMed , DOI )
Shichen Chang, Satoru Torii, Jun Inamo, Kinya Ishikawa, Yuta Kochi, Shigeomi Shimizu: Uncovering the Localization and Function of a Novel Read-Through Transcript ' TOMM40-APOE' Cells. 2023.12; 13 (1): ( PubMed , DOI )
Chisato Ono, Shinya Tanaka, Keiko Myouzen, Takeshi Iwasaki, Mahoko Ueda, Yoshinao Oda, Kazuhiko Yamamoto, Yuta Kochi, Yoshihiro Baba: Upregulated Fcrl5 disrupts B cell anergy causes autoimmune disease Frontiers in Immunology. 2023.09; 14 276014. ( DOI )
Mahoko Takahashi Ueda: Retrotransposon-derived transcripts and their functions associated with immunity and disease Genes & Genetic Systems. 2023.09; in press
Mitsui Y, Suzuki T, Kuniyoshi K, Inamo J, Yamaguchi K, Komuro M, Watanabe J, Edamoto M, Li S, Kouno T, Oba S, Hosoya T, Masuhiro K, Naito Y, Koyama S, Sakaguchi N, Standley DM, Shin JW, Akira S, Yasuda S, Miyazaki Y, Kochi Y, Kumanogoh A, Okamoto T, Satoh T: Expression of the readthrough transcript CiDRE in alveolar macrophages boosts SARS-CoV-2 susceptibility and promotes COVID-19 severity. Immunity. 2023.07; 56 (8): 1939-1954.e12. ( PubMed , DOI )
Nao Otomo, Anas M Khanshour, Masaru Koido, Kazuki Takeda, Yukihide Momozawa, Michiaki Kubo, Yoichiro Kamatani, John A Herring, Yoji Ogura, Yohei Takahashi, Shohei Minami, Koki Uno, Noriaki Kawakami, Manabu Ito, Tatsuya Sato, Kei Watanabe, Takashi Kaito, Haruhisa Yanagida, Hiroshi Taneichi, Katsumi Harimaya, Yuki Taniguchi, Hideki Shigematsu, Takahiro Iida, Satoru Demura, Ryo Sugawara, Nobuyuki Fujita, Mitsuru Yagi, Eijiro Okada, Naobumi Hosogane, Katsuki Kono, Masaya Nakamura, Kazuhiro Chiba, Toshiaki Kotani, Tsuyoshi Sakuma, Tsutomu Akazawa, Teppei Suzuki, Kotaro Nishida, Kenichiro Kakutani, Taichi Tsuji, Hideki Sudo, Akira Iwata, Satoshi Inami, Carol A Wise, Yuta Kochi, Morio Matsumoto, Shiro Ikegawa, Kota Watanabe, Chikashi Terao: Evidence of causality of low body mass index on risk of adolescent idiopathic scoliosis: a Mendelian randomization study. Front Endocrinol (Lausanne). 2023.06; 14 1089414. ( PubMed , DOI )
Fujitani H, Eguchi H, Kochi Y, Arai T, Muramatsu M, Okazaki Y: Rare germline variants in pancreatic cancer and multiple primary cancers: an autopsy study. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP). 2023.05; 32 (3): 286-297. ( PubMed , DOI )
Ishigaki K, Sakaue S, Terao C, Luo Y, Sonehara K, Yamaguchi K, Amariuta T, Too CL, Laufer VA, Scott IC, Viatte S, Takahashi M, Ohmura K, Murasawa A, Hashimoto M, Ito H, Hammoudeh M, Emadi SA, Masri BK, Halabi H, Badsha H, Uthman IW, Wu X, Lin L, Li T, Plant D, Barton A, Orozco G, Verstappen SMM, Bowes J, MacGregor AJ, Honda S, Koido M, Tomizuka K, Kamatani Y, Tanaka H, Tanaka E, Suzuki A, Maeda Y, Yamamoto K, Miyawaki S, Xie G, Zhang J, Amos CI, Keystone E, Wolbink G, van der Horst-Bruinsma I, Cui J, Liao KP, Carroll RJ, Lee HS, Bang SY, Siminovitch KA, de Vries N, Alfredsson L, Rantapää-Dahlqvist S, Karlson EW, Bae SC, Kimberly RP, Edberg JC, Mariette X, Huizinga T, Dieudé P, Schneider M, Kerick M, Denny JC, BioBank Japan Project, Matsuda K, Matsuo K, Mimori T, Matsuda F, Fujio K, Tanaka Y, Kumanogoh A, Traylor M, Lewis CM, Eyre S, Xu H, Saxena R, Arayssi T, Kochi Y, Ikari K, Harigai M, Gregersen PK, Yamamoto K, Louis Bridges S Jr, Padyukov L, Martin J, Klareskog L, Okada Y, Raychaudhuri S: Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis. Nature genetics. 2022.11; 54 (11): 1640-1651. ( PubMed , DOI )
Yamaguchi K, Ishigaki K, Suzuki A, Tsuchida Y, Tsuchiya H, Sumitomo S, Nagafuchi Y, Miya F, Tsunoda T, Shoda H, Fujio K, Yamamoto K, Kochi Y: Splicing QTL analysis focusing on coding sequences reveals mechanisms for disease susceptibility loci. Nature communications. 2022.08; 13 (1): 4659. ( PubMed , DOI )
Kato D, Mitsuhashi S, Miya F, Saitoh S, Okamoto N, Tsunoda T, Kochi Y: Utility of tissue-specific gene expression scores for gene prioritization in Mendelian diseases. Journal of human genetics. 2022.08; 67 (12): 739-742. ( PubMed , DOI )
Scofield RH, Lewis VM, Cavitt J, Kurien BT, Assassi S, Martin J, Gorlova O, Gregersen P, Lee A, Rider LG, O'Hanlon T, Rothwell S, Lilleker J, Myositis Genetics Consortium, Xiaoxi Liu., Kochi Y, Terao C, Igoe A, Stevens W, Sahhar J, Roddy J, Rischmueller M, Lester S, Proudman S, Chen S, Brown MA, Mayes MD, Lamb JA, Miller FW: 47XXY and 47XXX in Scleroderma and Myositis. ACR open rheumatology. 2022.06; 4 (6): 528-533. ( PubMed , DOI )
Iwasaki Y, Takeshima Y, Nakano M, Okubo M, Ota M, Suzuki A, Kochi Y, Okamura T, Endo T, Miki I, Sakurada K, Yamamoto K, Fujio K: Combined plasma metabolomic and transcriptomic analysis identify histidine as a biomarker and potential contributor in SLE pathogenesis. Rheumatology (Oxford, England). 2022.06; 62 (2): 905-913. ( PubMed , DOI )
Yin X, Kim K, Suetsugu H, Bang SY, Wen L, Koido M, Ha E, Liu L, Sakamoto Y, Jo S, Leng RX, Otomo N, Kwon YC, Sheng Y, Sugano N, Hwang MY, Li W, Mukai M, Yoon K, Cai M, Ishigaki K, Chung WT, Huang H, Takahashi D, Lee SS, Wang M, Karino K, Shim SC, Zheng X, Miyamura T, Kang YM, Ye D, Nakamura J, Suh CH, Tang Y, Motomura G, Park YB, Ding H, Kuroda T, Choe JY, Li C, Niiro H, Park Y, Shen C, Miyamoto T, Ahn GY, Fei W, Takeuchi T, Shin JM, Li K, Kawaguchi Y, Lee YK, Wang YF, Amano K, Park DJ, Yang W, Tada Y, Lau YL, Yamaji K, Zhu Z, Shimizu M, Atsumi T, Suzuki A, Sumida T, Okada Y, Matsuda K, Matsuo K, Kochi Y, Japanese Research Committee on Idiopathic Osteonecrosis of the Femoral Head., Yamamoto K, Ohmura K, Kim TH, Yang S, Yamamoto T, Kim BJ, Shen N, Ikegawa S, Lee HS, Zhang X, Terao C, Cui Y, Bae SC: Biological insights into systemic lupus erythematosus through an immune cell-specific transcriptome-wide association study. Annals of the rheumatic diseases. 2022.05; 81 (9): 1273-80. ( PubMed , DOI )
Takeshima Y, Iwasaki Y, Nakano M, Narushima Y, Ota M, Nagafuchi Y, Sumitomo S, Okamura T, Elkon K, Ishigaki K, Suzuki A, Kochi Y, Yamamoto K, Fujio K: Immune cell multiomics analysis reveals contribution of oxidative phosphorylation to B-cell functions and organ damage of lupus. Annals of the rheumatic diseases. 2022.03; 81 (6): 845-853. ( PubMed , DOI )
Honda S, Ikari K, Yano K, Terao C, Tanaka E, Harigai M, Kochi Y: Polygenic risk scores are associated with radiographic progression in patients with rheumatoid arthritis. Arthritis & rheumatology (Hoboken, N.J.). 2022.01; 74 (5): 791-800. ( PubMed , DOI )
Suetsugu H, Kim K, Yamamoto T, Bang SY, Sakamoto Y, Shin JM, Sugano N, Kim JS, Mukai M, Lee YK, Ohmura K, Park DJ, Takahashi D, Ahn GY, Karino K, Kwon YC, Miyamura T, Kim J, Nakamura J, Motomura G, Kuroda T, Niiro H, Miyamoto T, Takeuchi T, Ikari K, Amano K, Tada Y, Yamaji K, Shimizu M, Atsumi T, Seki T, Tanaka Y, Kubo T, Hisada R, Yoshioka T, Yamazaki M, Kabata T, Kajino T, Ohta Y, Okawa T, Naito Y, Kaneuji A, Yasunaga Y, Ohzono K, Tomizuka K, Koido M, Matsuda K, Okada Y, Suzuki A, Kim BJ, Kochi Y, Lee HS, Ikegawa S, Bae SC, Terao C: Novel susceptibility loci for steroid-associated osteonecrosis of the femoral head in systemic lupus erythematosus. Human molecular genetics. 2021.12; 31 (7): 1082-1095. ( PubMed , DOI )
Otomo N, Lu HF, Koido M, Kou I, Takeda K, Momozawa Y, Kubo M, Kamatani Y, Ogura Y, Takahashi Y, Nakajima M, Minami S, Uno K, Kawakami N, Ito M, Sato T, Watanabe K, Kaito T, Yanagida H, Taneichi H, Harimaya K, Taniguchi Y, Shigematsu H, Iida T, Demura S, Sugawara R, Fujita N, Yagi M, Okada E, Hosogane N, Kono K, Nakamura M, Chiba K, Kotani T, Sakuma T, Akazawa T, Suzuki T, Nishida K, Kakutani K, Tsuji T, Sudo H, Iwata A, Kaneko K, Inami S, Kochi Y, Chang WC, Matsumoto M, Watanabe K, Ikegawa S, Terao C: Polygenic Risk Score of Adolescent Idiopathic Scoliosis for Potential Clinical Use. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2021.08; 36 (8): 1481-1491. ( PubMed , DOI )
Tanaka N, Koido M, Suzuki A, Otomo N, Suetsugu H, Kochi Y, Tomizuka K, Momozawa Y, Kamatani Y, Biobank Japan Project., Ikegawa S, Yamamoto K, Terao C: Eight novel susceptibility loci and putative causal variants in atopic dermatitis. The Journal of allergy and clinical immunology. 2021.06; 148 (5): 1293-1306. ( PubMed , DOI )
Tsuji H, Ohmura K, Jin H, Naito R, Arase N, Kohyama M, Suenaga T, Sakakibara S, Kochi Y, Okada Y, Yamamoto K, Kikutani H, Morinobu A, Mimori T, Arase H: Anti-dsDNA antibodies recognize DNA presented on HLA class II molecules of systemic lupus erythematosus risk alleles. Arthritis & rheumatology (Hoboken, N.J.). 2021.06; 74 (1): 105-111. ( PubMed , DOI )
Kosugi Y, Uriu K, Suzuki N, Yamamoto K, Nagaoka S, Kimura I, Konno Y, Aso H, Willett BJ, Kobayashi T, Koyanagi Y, Ueda MT, Ito J, Sato K: Comprehensive Investigation on the Interplay between Feline APOBEC3Z3 Proteins and Feline Immunodeficiency Virus Vif Proteins. Journal of virology. 2021.06; 95 (13): e0017821. ( PubMed , DOI )
Singh B, Maiti GP, Zhou X, Fazel-Najafabadi M, Bae SC, Sun C, Terao C, Okada Y, Chua KH, Kochi Y, Guthridge JM, Zhang H, Weirauch M, James JA, Harley JB, Varshney GK, Looger LL, Nath SK: Lupus susceptibility region containing CDKN1B rs34330 mechanistically influences expression and function of multiple target genes, also linked to proliferation and apoptosis. Arthritis & rheumatology (Hoboken, N.J.). 2021.05; 73 (12): 2303-2313. ( PubMed , DOI )
Ota M, Nagafuchi Y, Hatano H, Ishigaki K, Terao C, Takeshima Y, Yanaoka H, Kobayashi S, Okubo M, Shirai H, Sugimori Y, Maeda J, Nakano M, Yamada S, Yoshida R, Tsuchiya H, Tsuchida Y, Akizuki S, Yoshifuji H, Ohmura K, Mimori T, Yoshida K, Kurosaka D, Okada M, Setoguchi K, Kaneko H, Ban N, Yabuki N, Matsuki K, Mutoh H, Oyama S, Okazaki M, Tsunoda H, Iwasaki Y, Sumitomo S, Shoda H, Kochi Y, Okada Y, Yamamoto K, Okamura T, Fujio K: Dynamic landscape of immune cell-specific gene regulation in immune-mediated diseases. Cell. 2021.05; 184 (11): 3006-3021.e17. ( PubMed , DOI )
Matsuzawa Ayumi, Lee Jiyoung, Nakagawa So, Itoh Johbu, Takahashi Ueda Mahoko, Mitsuhashi Satomi, Kochi Yuta, Kaneko-Ishino Tomoko, Ishino Fumitoshi: HERV-Derived Ervpb1 Is Conserved in Simiiformes, Exhibiting Expression in Hematopoietic Cell Lineages Including Macrophages INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021.05; 22 (9): ( DOI )
Chikuma S, Yamanaka S, Nakagawa S, Ueda MT, Hayabuchi H, Tokifuji Y, Kanayama M, Okamura T, Arase H, Yoshimura A: TRIM28 Expression on Dendritic Cells Prevents Excessive T Cell Priming by Silencing Endogenous Retrovirus. Journal of immunology (Baltimore, Md. : 1950). 2021.02; 206 (7): 1528-1539. ( PubMed , DOI )
Inamo J, Kochi Y, Takeuchi T: Is type 2 diabetes mellitus an inverse risk factor for the development of rheumatoid arthritis? Journal of human genetics. 2021.02; 66 (2): 219-223. ( PubMed , DOI )
Inamo Jun, Kochi Yuta, Takeuchi Tsutomu: 2型糖尿病は関節リウマチ発症の逆危険因子であるか(Is type 2 diabetes mellitus an inverse risk factor for the development of rheumatoid arthritis?) Journal of Human Genetics. 2021.02; 66 (2): 219-223. ( 医中誌 )
Bing N, Zhou H, Chen X, Hirose T, Kochi Y, Tsuchida Y, Ishigaki K, Sumitomo S, Fujio K, Zhang B, Valdez H, Vincent MS, Martin D, Clark JD: Contribution of a European-Prevalent Variant near CD83 and an East Asian-Prevalent Variant near IL17RB to Herpes Zoster Risk in Tofacitinib Treatment: Results of Genome-Wide Association Study Meta-Analyses. Arthritis & rheumatology (Hoboken, N.J.). 2021.01; 73 (7): 1155-1166. ( PubMed , DOI )
Yin X, Kim K, Suetsugu H, Bang SY, Wen L, Koido M, Ha E, Liu L, Sakamoto Y, Jo S, Leng RX, Otomo N, Laurynenka V, Kwon YC, Sheng Y, Sugano N, Hwang MY, Li W, Mukai M, Yoon K, Cai M, Ishigaki K, Chung WT, Huang H, Takahashi D, Lee SS, Wang M, Karino K, Shim SC, Zheng X, Miyamura T, Kang YM, Ye D, Nakamura J, Suh CH, Tang Y, Motomura G, Park YB, Ding H, Kuroda T, Choe JY, Li C, Niiro H, Park Y, Shen C, Miyamoto T, Ahn GY, Fei W, Takeuchi T, Shin JM, Li K, Kawaguchi Y, Lee YK, Wang Y, Amano K, Park DJ, Yang W, Tada Y, Yamaji K, Shimizu M, Atsumi T, Suzuki A, Sumida T, Okada Y, Matsuda K, Matsuo K, Kochi Y, Japanese Research Committee on Idiopathic Osteonecrosis of the Femoral Head., Kottyan LC, Weirauch MT, Parameswaran S, Eswar S, Salim H, Chen X, Yamamoto K, Harley JB, Ohmura K, Kim TH, Yang S, Yamamoto T, Kim BJ, Shen N, Ikegawa S, Lee HS, Zhang X, Terao C, Cui Y, Bae SC: Meta-analysis of 208370 East Asians identifies 113 susceptibility loci for systemic lupus erythematosus. Annals of the rheumatic diseases. 2020.12; 80 (5): 632-640. ( PubMed , DOI )
Tsuchiya H, Ota M, Sumitomo S, Ishigaki K, Suzuki A, Sakata T, Tsuchida Y, Inui H, Hirose J, Kochi Y, Kadono Y, Shirahige K, Tanaka S, Yamamoto K, Fujio K: Parsing multiomics landscape of activated synovial fibroblasts highlights drug targets linked to genetic risk of rheumatoid arthritis. Annals of the rheumatic diseases. 2020.11; 80 (4): 440-450. ( PubMed , DOI )
Nakano Y, Yamamoto K, Ueda MT, Soper A, Konno Y, Kimura I, Uriu K, Kumata R, Aso H, Misawa N, Nagaoka S, Shimizu S, Mitsumune K, Kosugi Y, Juarez-Fernandez G, Ito J, Nakagawa S, Ikeda T, Koyanagi Y, Harris RS, Sato K: A role for gorilla APOBEC3G in shaping lentivirus evolution including transmission to humans. PLoS pathogens. 2020.09; 16 (9): e1008812. ( PubMed , DOI )
Ueda Mahoko Takahashi, Kryukov Kirill, Mitsuhashi Satomi, Mitsuhashi Hiroaki, Imanishi Tadashi, Nakagawa So: Comprehensive genomic analysis reveals dynamic evolution of endogenous retroviruses that code for retroviral-like protein domains MOBILE DNA. 2020.09; 11 (1): 29. ( PubMed , DOI )
Kryukov Kirill, Ueda Mahoko Takahashi, Nakagawa So, Imanishi Tadashi: Sequence Compression Benchmark (SCB) database-A comprehensive evaluation of reference-free compressors for FASTA-formatted sequences GIGASCIENCE. 2020.07; 9 (7): ( PubMed , DOI )
Oka A, Takagi A, Komiyama E, Yoshihara N, Mano S, Hosomichi K, Suzuki S, Haida Y, Motosugi N, Hatanaka T, Kimura M, Ueda MT, Nakagawa S, Miura H, Ohtsuka M, Tanaka M, Komiyama T, Otomo A, Hadano S, Mabuchi T, Beck S, Inoko H, Ikeda S: Alopecia areata susceptibility variant in MHC region impacts expressions of genes contributing to hair keratinization and is involved in hair loss. EBioMedicine. 2020.07; 57 102810. ( PubMed , DOI )
Ishigaki K, Akiyama M, Kanai M, Takahashi A, Kawakami E, Sugishita H, Sakaue S, Matoba N, Low SK, Okada Y, Terao C, Amariuta T, Gazal S, Kochi Y, Horikoshi M, Suzuki K, Ito K, Koyama S, Ozaki K, Niida S, Sakata Y, Sakata Y, Kohno T, Shiraishi K, Momozawa Y, Hirata M, Matsuda K, Ikeda M, Iwata N, Ikegawa S, Kou I, Tanaka T, Nakagawa H, Suzuki A, Hirota T, Tamari M, Chayama K, Miki D, Mori M, Nagayama S, Daigo Y, Miki Y, Katagiri T, Ogawa O, Obara W, Ito H, Yoshida T, Imoto I, Takahashi T, Tanikawa C, Suzuki T, Sinozaki N, Minami S, Yamaguchi H, Asai S, Takahashi Y, Yamaji K, Takahashi K, Fujioka T, Takata R, Yanai H, Masumoto A, Koretsune Y, Kutsumi H, Higashiyama M, Murayama S, Minegishi N, Suzuki K, Tanno K, Shimizu A, Yamaji T, Iwasaki M, Sawada N, Uemura H, Tanaka K, Naito M, Sasaki M, Wakai K, Tsugane S, Yamamoto M, Yamamoto K, Murakami Y, Nakamura Y, Raychaudhuri S, Inazawa J, Yamauchi T, Kadowaki T, Kubo M, Kamatani Y: Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Nature genetics. 2020.07; 52 (7): 669-679. ( PubMed , DOI )
Otomo A, Ueda MT, Fujie T, Hasebe A, Suematsu Y, Okamura Y, Takeoka S, Hadano S, Nakagawa S: Efficient differentiation and polarization of primary cultured neurons on poly(lactic acid) scaffolds with microgrooved structures. Scientific reports. 2020.04; 10 (1): 6716. ( PubMed , DOI )
Ono Chisato, Kochi Yuta, Tanaka Shinya, Yamamoto Kazuhiko, Baba Yoshihiro: Systemic lupus erythematosus and other systemic autoimmune diseases Role of Fcrl5 in B cell immune response and peripheral tolerance(和訳中) 日本免疫学会総会・学術集会記録. 2019.11; 48 (Proceedings): 2-B. ( 医中誌 )
Kryukov K, Ueda MT, Nakagawa S, Imanishi T: Nucleotide Archival Format (NAF) enables efficient lossless reference-free compression of DNA sequences. Bioinformatics (Oxford, England). 2019.10; 35 (19): 3826-3828. ( PubMed , DOI )
Motegi T, Kochi Y, Matsuda K, Kubo M, Yamamoto K, Momozawa Y: Identification of rare coding variants in TYK2 protective for rheumatoid arthritis in the Japanese population and their effects on cytokine signalling. Annals of the rheumatic diseases. 2019.08; 78 (8): 1062-1069. ( PubMed , DOI )
Akizuki S, Ishigaki K, Kochi Y, Law SM, Matsuo K, Ohmura K, Suzuki A, Nakayama M, Iizuka Y, Koseki H, Ohara O, Hirata J, Kamatani Y, Matsuda F, Sumida T, Yamamoto K, Okada Y, Mimori T, Terao C: PLD4 is a genetic determinant to systemic lupus erythematosus and involved in murine autoimmune phenotypes. Annals of the rheumatic diseases. 2019.04; 78 (4): 509-518. ( PubMed , DOI )
Okada Y, Eyre S, Suzuki A, Kochi Y, Yamamoto K: Genetics of rheumatoid arthritis: 2018 status. Annals of the rheumatic diseases. 2019.04; 78 (4): 446-453. ( PubMed , DOI )
Molineros JE, Looger LL, Kim K, Okada Y, Terao C, Sun C, Zhou XJ, Raj P, Kochi Y, Suzuki A, Akizuki S, Nakabo S, Bang SY, Lee HS, Kang YM, Suh CH, Chung WT, Park YB, Choe JY, Shim SC, Lee SS, Zuo X, Yamamoto K, Li QZ, Shen N, Porter LL, Harley JB, Chua KH, Zhang H, Wakeland EK, Tsao BP, Bae SC, Nath SK: Amino acid signatures of HLA Class-I and II molecules are strongly associated with SLE susceptibility and autoantibody production in Eastern Asians. PLoS genetics. 2019.04; 15 (4): e1008092. ( PubMed , DOI )
Kryukov K, Ueda MT, Imanishi T, Nakagawa S: Systematic survey of non-retroviral virus-like elements in eukaryotic genomes. Virus research. 2019.03; 262 30-36. ( PubMed , DOI )
Hatano Hiroaki, Ota Mineto, Takeshima Yusuke, Iwasaki Yukiko, Nagafuchi Yasuo, Kochi Yuta, Shoda Hirofumi, Okamura Tomohisa, Fujio Keishi, Yamamoto Kazuhiko: 遺伝学 全身性エリテマトーデス(SLE)と関節リウマチ(RA)患者の末梢血単核球細胞(PBMCs)の多様な免疫細胞サブセットにおけるsplicing quantitative trait loci(sQTL)の影響に関する包括的研究(Genetics A comprehensive study of splicing quantitative trait loci(sQTL) effects in various immune cell subsets in peripheral blood mononuclear cells(PBMCs) of systemic lupus erythematosus(SLE) and rheumatoid arthritis(RA) patients) 日本リウマチ学会総会・学術集会プログラム・抄録集. 2019.03; 63回 325. ( 医中誌 )
Otani T, Noma H, Sugasawa S, Kuchiba A, Goto A, Yamaji T, Kochi Y, Iwasaki M, Matsui S, Tsunoda T: Exploring predictive biomarkers from clinical genome-wide association studies via multidimensional hierarchical mixture models. European journal of human genetics : EJHG. 2019.01; 27 (1): 140-149. ( PubMed , DOI )
Sato K, Otomo A, Ueda MT, Hiratsuka Y, Suzuki-Utsunomiya K, Sugiyama J, Murakoshi S, Mitsui S, Ono S, Nakagawa S, Shang HF, Hadano S: Altered oligomeric states in pathogenic ALS2 variants associated with juvenile motor neuron diseases cause loss of ALS2-mediated endosomal function. The Journal of biological chemistry. 2018.11; 293 (44): 17135-17153. ( PubMed , DOI )
Chikashi Terao, Hajime Yoshifuji, Takayoshi Matsumura, Taeko K Naruse, Tomonori Ishii, Yoshikazu Nakaoka, Yohei Kirino, Keitaro Matsuo, Tomoki Origuchi, Masakazu Shimizu, Yasuhiro Maejima, Eisuke Amiya, Natsuko Tamura, Takahisa Kawaguchi, Meiko Takahashi, Kazuya Setoh, Koichiro Ohmura, Ryu Watanabe, Tetsuya Horita, Tatsuya Atsumi, Mitsuru Matsukura, Tetsuro Miyata, Yuta Kochi, Toshio Suda, Kazuo Tanemoto, Akira Meguro, Yukinori Okada, Akiyoshi Ogimoto, Motohisa Yamamoto, Hiroki Takahashi, Shingo Nakayamada, Kazuyoshi Saito, Masataka Kuwana, Nobuhisa Mizuki, Yasuharu Tabara, Atsuhisa Ueda, Issei Komuro, Akinori Kimura, Mitsuaki Isobe, Tsuneyo Mimori, Fumihiko Matsuda: Genetic determinants and an epistasis of LILRA3 and HLA-B*52 in Takayasu arteritis Proc. Natl. Acad. Sci. U.S.A.. 2018.11; 115 (51): 13045-13050. ( PubMed , DOI )
Tsuchida Y, Sumitomo S, Ota M, Tsuchiya H, Nagafuchi Y, Shoda H, Fujio K, Ishigaki K, Yamaguchi K, Suzuki A, Kochi Y, Yamamoto K: Reduction of CD83 Expression on B Cells and the Genetic Basis for Rheumatoid Arthritis: Comment on the Article by Thalayasingam et al. Arthritis & rheumatology (Hoboken, N.J.). 2018.10; 70 (10): 1695-1696. ( PubMed , DOI )
三橋 里美, 中川 草, 上田 真保子, 今西 規, 三橋 弘明, フリス・マーティン : 筋機能と病態研究のフロンティア ナノポアシークエンサーを用いたD4Z4リピートの解析 日本筋学会学術集会プログラム・抄録集. 2018.08; 4回 31. ( 医中誌 )
Sakurai K, Ishigaki K, Shoda H, Nagafuchi Y, Tsuchida Y, Sumitomo S, Kanda H, Suzuki A, Kochi Y, Yamamoto K, Fujio K: HLA-DRB1 Shared Epitope Alleles and Disease Activity Are Correlated with Reduced T Cell Receptor Repertoire Diversity in CD4+ T Cells in Rheumatoid Arthritis. The Journal of rheumatology. 2018.07; 45 (7): 905-914. ( PubMed , DOI )
Sumitomo S, Nagafuchi Y, Tsuchida Y, Tsuchiya H, Ota M, Ishigaki K, Nakachi S, Kato R, Sakurai K, Hanata N, Tateishi S, Kanda H, Suzuki A, Kochi Y, Fujio K, Yamamoto K: A gene module associated with dysregulated TCR signaling pathways in CD4+ T cell subsets in rheumatoid arthritis. Journal of autoimmunity. 2018.05; 89 21-29. ( PubMed , DOI )
Konno Y, Nagaoka S, Kimura I, Yamamoto K, Kagawa Y, Kumata R, Aso H, Ueda MT, Nakagawa S, Kobayashi T, Koyanagi Y, Sato K: New World feline APOBEC3 potently controls inter-genus lentiviral transmission. Retrovirology. 2018.04; 15 (1): 31. ( PubMed , DOI )
Kochi Y, Kamatani Y, Kondo Y, Suzuki A, Kawakami E, Hiwa R, Momozawa Y, Fujimoto M, Jinnin M, Tanaka Y, Kanda T, Cooper RG, Chinoy H, Rothwell S, Lamb JA, Vencovský J, Mann H, Ohmura K, Myouzen K, Ishigaki K, Nakashima R, Hosono Y, Tsuboi H, Kawasumi H, Iwasaki Y, Kajiyama H, Horita T, Ogawa-Momohara M, Takamura A, Tsunoda S, Shimizu J, Fujio K, Amano H, Mimori A, Kawakami A, Umehara H, Takeuchi T, Sano H, Muro Y, Atsumi T, Mimura T, Kawaguchi Y, Mimori T, Takahashi A, Kubo M, Kohsaka H, Sumida T, Yamamoto K: Splicing variant of WDFY4 augments MDA5 signalling and the risk of clinically amyopathic dermatomyositis. Annals of the rheumatic diseases. 2018.04; 77 (4): 602-611. ( PubMed , DOI )
Kurosaki Y, Ueda MT, Nakano Y, Yasuda J, Koyanagi Y, Sato K, Nakagawa S: Different effects of two mutations on the infectivity of Ebola virus glycoprotein in nine mammalian species. The Journal of general virology. 2018.02; 99 (2): 181-186. ( PubMed , DOI )
Ishigaki K, Kochi Y, Yamamoto K: Genetics of human autoimmunity: From genetic information to functional insights. Clinical immunology (Orlando, Fla.). 2018.01; 186 9-13. ( PubMed , DOI )
Sumitomo S, Nagafuchi Y, Tsuchida Y, Tsuchiya H, Ota M, Ishigaki K, Suzuki A, Kochi Y, Fujio K, Yamamoto K: Transcriptome analysis of peripheral blood from patients with rheumatoid arthritis: a systematic review. Inflammation and regeneration. 2018; 38 21. ( PubMed , DOI )
Nishino J, Ochi H, Kochi Y, Tsunoda T, Matsui S: Sample Size for Successful Genome-Wide Association Study of Major Depressive Disorder. Frontiers in genetics. 2018; 9 227. ( PubMed , DOI )
A naturally occurring feline APOBEC3 variant that loses anti-lentiviral activity by lacking two amino acid residues Journal of General Virology. 2018; 99 704-709.
Nishino J, Kochi Y, Shigemizu D, Kato M, Ikari K, Ochi H, Noma H, Matsui K, Morizono T, Boroevich KA, Tsunoda T, Matsui S: Empirical Bayes Estimation of Semi-parametric Hierarchical Mixture Models for Unbiased Characterization of Polygenic Disease Architectures. Frontiers in genetics. 2018; 9 115. ( PubMed , DOI )
Terao C, Okada Y, Ikari K, Kochi Y, Suzuki A, Ohmura K, Matsuo K, Taniguchi A, Kubo M, Raychaudhuri S, Yamamoto K, Yamanaka H, Kamatani Y, Mimori T, Matsuda F: Genetic landscape of interactive effects of HLA-DRB1 alleles on susceptibility to ACPA(+) rheumatoid arthritis and ACPA levels in Japanese population. Journal of medical genetics. 2017.12; 54 (12): 853-858. ( PubMed , DOI )
Mitsuhashi S, Nakagawa S, Takahashi Ueda M, Imanishi T, Frith MC, Mitsuhashi H: Nanopore-based single molecule sequencing of the D4Z4 array responsible for facioscapulohumeral muscular dystrophy. Scientific reports. 2017.11; 7 (1): 14789. ( PubMed , DOI )
Oka A, Asano Y, Hasegawa M, Fujimoto M, Ishikawa O, Kuwana M, Kawaguchi Y, Yamamoto T, Takahashi H, Goto D, Endo H, Jinnin M, Mano S, Hosomichi K, Mabuchi T, Ueda MT, Nakagawa S, Beck S, Bahram S, Takehara K, Sato S, Ihn H: RXRB Is an MHC-Encoded Susceptibility Gene Associated with Anti-Topoisomerase I Antibody-Positive Systemic Sclerosis. The Journal of investigative dermatology. 2017.09; 137 (9): 1878-1886. ( PubMed , DOI )
Ishigaki Kazuyoshi, Kochi Yuta, Suzuki Akari, Tsuchida Yumi, Tsuchiya Haruka, Sumitomo Shuji, Yamaguchi Kensuke, Nagafuchi Yasuo, Nakachi Shinichiro, Kato Rika, Sakurai Keiichi, Shoda Hirofumi, Ikari Katsunori, Taniguchi Atsuo, Yamanaka Hisashi, Miya Fuyuki, Tsunoda Tatsuhiko, Okada Yukinori, Momozawa Yukihide, Kamatani Yoichiro, Yamada Ryo, Kubo Michiaki, Fujio Keishi, Yamamoto Kazuhiko: Polygenic burdens on cell-specific pathways underlie the risk of rheumatoid arthritis NATURE GENETICS. 2017.07; 49 (7): 1120-+. ( PubMed , DOI )
Nitta T, Kochi Y, Muro R, Tomofuji Y, Okamura T, Murata S, Suzuki H, Sumida T, Yamamoto K, Takayanagi H: Human thymoproteasome variations influence CD8 T cell selection. Science immunology. 2017.06; 2 (12): ( PubMed , DOI )
Molineros JE, Yang W, Zhou XJ, Sun C, Okada Y, Zhang H, Heng Chua K, Lau YL, Kochi Y, Suzuki A, Yamamoto K, Ma J, Bang SY, Lee HS, Kim K, Bae SC, Zhang H, Shen N, Looger LL, Nath SK: Confirmation of five novel susceptibility loci for systemic lupus erythematosus (SLE) and integrated network analysis of 82 SLE susceptibility loci. Human molecular genetics. 2017.03; 26 (6): 1205-1216. ( PubMed , DOI )
Ueda MT, Kurosaki Y, Izumi T, Nakano Y, Oloniniyi OK, Yasuda J, Koyanagi Y, Sato K, Nakagawa S: Functional mutations in spike glycoprotein of Zaire ebolavirus associated with an increase in infection efficiency. Genes to cells : devoted to molecular & cellular mechanisms. 2017.02; 22 (2): 148-159. ( PubMed , DOI )
Tsuchida Y, Sumitomo S, Ishigaki K, Suzuki A, Kochi Y, Tsuchiya H, Ota M, Komai T, Inoue M, Morita K, Okamura T, Yamamoto K, Fujio K: TGF-β3 Inhibits Antibody Production by Human B Cells. PloS one. 2017; 12 (1): e0169646. ( PubMed , DOI )
Nakagawa S, Takahashi MU: gEVE: a genome-based endogenous viral element database provides comprehensive viral protein-coding sequences in mammalian genomes Database. 2016; baw087.
Takahashi M, Saitou N: Identification and characterization of lineage-specific highly conserved noncoding sequences in mammalian genomes. Genome Biology and Evolution. 2012; 4 641-657.
Prakash T, Oshima K, Morita H, Fukuda S, Imaoka A, Kumar N., Sharma VK, Takahashi M, Saitou N, Taylor TD, Ohno H, Umesaki Y, Hattori M: Complete genome sequences of rat and mouse segmented filamentous bacteria, a potent inducer of Th17 cell differentiation Cell Host & Microbe. 2011;
高地 雄太: 【関節リウマチの最新の理解とマネジメント】関節リウマチの遺伝素因 日本内科学会雑誌. 2023.10; 112 (10): 1880-1884. ( 医中誌 )
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Tadaka Kosuke, Ueda Mahoko Takahashi, Shichinohe Shintaro, Kida Yurie, Ono Chikako, Matsura Yoshiharu, Watarbe Tokiko, Nakagawa So: Genomic diversity of SARS-CoV-2 can be accelerated by mutations in the nsp14 gene ISCIENCE. 2023.03; 26 (3): 106210. ( PubMed , DOI )
高地 雄太: 【皮膚筋炎とその周辺】炎症性筋疾患と遺伝的素因 皮膚科. 2023.01; 3 (1): 1-5. ( 医中誌 )
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太田 峰人, 永渕 泰雄, 波多野 裕明, 石垣 和慶, 竹島 雄介, 柳岡 治先, 小林 聖未, 大久保 麻衣, 杉森 祐介, 前田 淳子, 中野 正博, 山田 紗依子, 吉田 良知, 岩崎 由希子, 住友 秀次, 庄田 宏文, 高地 雄太, 山本 一彦, 岡村 僚久, 藤尾 圭志: 機能ゲノム解析による全身性免疫疾患へのアプローチ 日本臨床免疫学会総会プログラム・抄録集. 2020.10; 48回 76. ( 医中誌 )
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Kochi Y: [TRANSCRIPTOME ANALYSIS OF IMMUNE CELLS AND DISEASE SUSCEPTIBLE GENES]. Arerugi = [Allergy]. 2020; 69 (10): 947-951. ( PubMed , DOI )
土田 優美, 太田 峰人, 石垣 和慶, 住友 秀次, 山口 健介, 永渕 泰雄, 土屋 遥香, 庄田 宏文, 鈴木 亜香里, 山本 一彦, 高地 雄太, 藤尾 圭志: 刺激下でのCD4陽性T細胞におけるexpression quantitative trait locusの検討 日本臨床免疫学会総会プログラム・抄録集. 2019.10; 47回 122. ( 医中誌 )
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中川 草, 上田 真保子, 中野 雄介, 安田 二朗, 小柳 義夫, 佐藤 佳, 黒崎 陽平: 微生物・感染症学における多様なDry解析アプローチ 公共データベースを活用したエボラウイルスGP遺伝子の感染効率に関与する塩基突然変異の同定 日本獣医学会学術集会講演要旨集. 2018.08; 161回 209. ( 医中誌 )
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