生命機能医学分野

52  件  
※ 登録方法の違いにより重複して表示されている場合があります。

  1. Yang T, Nakanishi H, Itaka K: Development of a new caged intein for multi-input conditional translation of synthetic mRNA. Scientific reports. 2024.05; 14 (1): 9988. ( PubMed , DOI )

  1. Du X, Yada E, Terai Y, Takahashi T, Nakanishi H, Tanaka H, Akita H, Itaka K: Comprehensive Evaluation of Lipid Nanoparticles and Polyplex Nanomicelles for Muscle-Targeted mRNA Delivery. Pharmaceutics. 2023.09; 15 (9): 2291. ( PubMed , DOI )

  2. Zhang Maorui, Fukushima Yuta, Nozaki Kosuke, Nakanishi Hideyuki, Deng Jia, Wakabayashi Noriyuki, Itaka Keiji: メッセンジャーRNAを用いた血管新生因子と骨形成因子の同時投与による骨再生の増強(Enhancement of bone regeneration by coadministration of angiogenic and osteogenic factors using messenger RNA) Inflammation and Regeneration. 2023.06; 43 1 of 16-16 of 16. ( 医中誌 )

  1. Jia Deng, Yuta Fukushima, Kosuke Nozaki, Hideyuki Nakanishi, Erica Yada, Yuki Terai, Kenji Fueki, Keiji Itaka: Anti-Inflammatory Therapy for Temporomandibular Joint Osteoarthritis Using mRNA Medicine Encoding Interleukin-1 Receptor Antagonist. Pharmaceutics. 2022.08; 14 (9): ( PubMed , DOI )

  2. Hideyuki Nakanishi, Tatsuyuki Yoshii, Shinya Tsukiji, Hirohide Saito: A protocol to construct RNA-protein devices for photochemical translational regulation of synthetic mRNAs in mammalian cells. STAR Protoc. 2022.06; 3 (2): 101451. ( PubMed , DOI )

  1. Hideyuki Nakanishi: Protein-Based Systems for Translational Regulation of Synthetic mRNAs in Mammalian Cells. Life (Basel). 2021.11; 11 (11): 1192. ( PubMed , DOI )

  2. Hashimoto Yasumasa, Kuniishi Hiroshi, Sakai Kazuhisa, Fukushima Yuta, Du Xuan, Yamashiro Kunihiko, Hori Kei, Motohashi Norio, Imamura Michihiro, Hoshino Mikio, Yamada Mitsuhiko, Araki Toshiyuki, Sakagami Hiroyuki, Takeda Shin'ichi, Itaka Keiji, Ichinohe Noritaka, Muntoni Francesco, Sekiguchi Masayuki, Aoki Yoshitsugu: Brain Dp140 alters glutamatergic transmission and social behaviour in Duchenne muscular dystrophy mouse model NEUROMUSCULAR DISORDERS. 2021.10; 31

  3. Nakanishi H, Yoshii T, Kawasaki S, Hayashi K, Tsutsui K, Oki C, Tsukiji S, Saito H: Light-controllable RNA-protein devices for translational regulation of synthetic mRNAs in mammalian cells. Cell chemical biology. 2021.05; 28 (5): 662-674.e5. ( PubMed , DOI )

  4. Fukushima Yuta, Uchida Satoshi, Imai Hideaki, Nakatomi Hirofumi, Kataoka Kazunori, Saito Nobuhito, Itaka Keiji: Treatment of ischemic neuronal death by introducing brain-derived neurotrophic factor mRNA using polyplex nanomicelle BIOMATERIALS. 2021.03; 270 120681. ( PubMed , DOI )

  5. Nakanishi H, Saito H: Purification of Specific Cell Populations Differentiated from Stem Cells Using MicroRNA-Responsive Synthetic Messenger RNAs. Methods in molecular biology (Clifton, N.J.). 2021; 2312 73-86. ( PubMed , DOI )

  1. Li Jinyu, Sasaki Naoko, Itaka Keiji, Terpstra Margo, Levato Riccardo, Matsusaki Michiya: Regulation of Chondrocyte Differentiation by Changing Intercellular Distances Using Type II Collagen Microfibers ACS BIOMATERIALS SCIENCE & ENGINEERING. 2020.10; 6 (10): 5711-5719. ( PubMed , DOI )

  2. Uchida S, Yanagihara K, Matsui A, Kataoka K, Itaka K: mRNA as a Tool for Gene Transfection in 3D Cell Culture for Future Regenerative Therapy. Micromachines. 2020.04; 11 (4): ( PubMed , DOI )

  3. Nakanishi H, Saito H: Caliciviral protein-based artificial translational activator for mammalian gene circuits with RNA-only delivery. Nature communications. 2020.03; 11 (1): 1297. ( PubMed , DOI )

  1. Hayashi K, Nozaki K, Tan Z, Fujita K, Nemoto R, Yamashita K, Miura H, Itaka K, Ohara S: Enhanced Antibacterial Property of Facet-Engineered TiO2 Nanosheet in Presence and Absence of Ultraviolet Irradiation. Materials (Basel, Switzerland). 2019.12; 13 (1): ( PubMed , DOI )

  2. Nakanishi H, Saito H: Mammalian gene circuits with biomolecule-responsive RNA devices. Current opinion in chemical biology. 2019.10; 52 16-22. ( PubMed , DOI )

  3. Matsumoto Masahito, Itaka Keiji: Pax6の骨およびグルコース代謝の調節における細胞分化を介した二重機能の役割 組織培養研究. 2019.06; 38 (2): 59. ( 医中誌 )

  4. Lin CY, Crowley ST, Uchida S, Komaki Y, Kataoka K, Itaka K: Treatment of Intervertebral Disk Disease by the Administration of mRNA Encoding a Cartilage-Anabolic Transcription Factor. Molecular therapy. Nucleic acids. 2019.02; 16 162-171. ( PubMed , DOI )

  1. Akitsugu Matsui, Satoshi Uchida, Akimasa Hayashi, Kazunori Kataoka, Keiji Itaka: Prolonged engraftment of transplanted hepatocytes in the liver by transient pro-survival factor supplementation using ex vivo mRNA transfection. J Control Release. 2018.09; 285 1-11. ( PubMed , DOI )

  2. Kayoko Yanagihara, Satoshi Uchida, Shinsuke Ohba, Kazunori Kataoka, Keiji Itaka: Treatment of Bone Defects by Transplantation of Genetically Modified Mesenchymal Stem Cell Spheroids. Mol Ther Methods Clin Dev. 2018.06; 9 358-366. ( PubMed , DOI )

  3. Samuel T Crowley, Kazunori Kataoka, Keiji Itaka: Combined CatWalk Index: an improved method to measure mouse motor function using the automated gait analysis system. BMC Res Notes. 2018.04; 11 (1): 263. ( PubMed , DOI )

  1. Y Anraku, H Kuwahara, Y Fukusato, A Mizoguchi, T Ishii, K Nitta, Y Matsumoto, K Toh, K Miyata, S Uchida, K Nishina, K Osada, K Itaka, N Nishiyama, H Mizusawa, T Yamasoba, T Yokota, K Kataoka: Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain. Nat Commun. 2017.10; 8 (1): 1001. ( PubMed , DOI )

  2. Satoshi Uchida, Naoto Yoshinaga, Kayoko Yanagihara, Eiji Yuba, Kazunori Kataoka, Keiji Itaka: Designing immunostimulatory double stranded messenger RNA with maintained translational activity through hybridization with poly A sequences for effective vaccination. Biomaterials. 2017.09; ( PubMed , DOI )

  3. Nakanishi H, Miki K, Komatsu KR, Umeda M, Mochizuki M, Inagaki A, Yoshida Y, Saito H: Monitoring and visualizing microRNA dynamics during live cell differentiation using microRNA-responsive non-viral reporter vectors. Biomaterials. 2017.06; 128 121-135. ( PubMed , DOI )

  4. Federico Perche, Satoshi Uchida, Hiroki Akiba, Chin-Yu Lin, Masaru Ikegami, Anjaneyulu Dirisala, Toshihiro Nakashima, Keiji Itaka, Kohei Tsumoto, Kazunori Kataoka: Improved Brain Expression of Anti-Amyloid β scFv by Complexation of mRNA Including a Secretion Sequence with PEG-based Block Catiomer. Curr Alzheimer Res. 2017.03; 14 (3): 295-302. ( PubMed , DOI )

  1. Nakanishi H, Higuchi Y, Yamashita F, Hashida M: Targeted gene integration using the combination of a sequence-specific DNA-binding protein and phiC31 integrase. Journal of biotechnology. 2014.09; 186 139-47. ( PubMed , DOI )

  1. Nakanishi H, Higuchi Y, Kawakami S, Yamashita F, Hashida M: Comparison of piggyBac transposition efficiency between linear and circular donor vectors in mammalian cells. Journal of biotechnology. 2011.07; 154 (4): 205-8. ( PubMed , DOI )

  1. Nakanishi H, Higuchi Y, Kawakami S, Yamashita F, Hashida M: piggyBac transposon-mediated long-term gene expression in mice. Molecular therapy : the journal of the American Society of Gene Therapy. 2010.04; 18 (4): 707-14. ( PubMed , DOI )

  1. 中西秀之, 位髙啓史: RNA修飾による炎症回避が，効果的なmRNAワクチンの開発を可能にした 科学. 2023.11; 93 (12): 1065-1069.

  2. 中西 秀之: 【mRNA創薬の新しい展開】細胞・臓器選択的な翻訳を可能にするmRNA医薬の設計 細胞. 2023.10; 55 (11): 876-880. ( 医中誌 )

  3. 申 育實, 中西 秀之, 位高 啓史: mRNAワクチン・mRNA医薬開発の現状 臨床免疫・アレルギー科. 2023.10; 80 (4): 467-477. ( 医中誌 )

  4. 中西 秀之, 位高 啓史: 細胞死誘導タンパク質をコードした合成mRNAによる選択的細胞除去 バイオマテリアル-生体材料-. 2023.10; 41 (4): 332-333. ( 医中誌 )

  5. 中西秀之: 細胞・臓器選択的な翻訳を可能にするmRNA医薬の設計 細胞. 2023.10; 55 (11): 876-880.

  6. Zhang Maorui, Fukushima Yuta, Nozaki Kosuke, Nakanishi Hideyuki, Deng Jia, Wakabayashi Noriyuki, Itaka Keiji: Enhancement of bone regeneration by coadministration of angiogenic and osteogenic factors using messenger RNA INFLAMMATION AND REGENERATION. 2023.06; 43 (1): ( DOI )

  7. 中西秀之，位髙啓史: mRNA医薬とmRNAワクチン 医学のあゆみ. 2023.04; 285 (5): 340-347.

  8. 中西 秀之, 位高 啓史: 【mRNAワクチンやゲノム編集で注目が集まる遺伝子治療】遺伝子導入技術　mRNA医薬とmRNAワクチン 医学のあゆみ. 2023.04; 285 (5): 340-347. ( 医中誌 )

  9. 中西秀之, 位髙啓史: mRNA医薬とmRNAワクチン 医学のあゆみ. 2023.04; 285 (5): 340-347.

  10. 中西秀之: 第13節 タンパク質をモジュールとするmRNA翻訳制御システムの構築 mRNAの制御機構の解明と治療薬・ワクチンへの活用. 2023.02; 115-136.

  11. Free Kendall, Nakanishi Hideyuki, Itaka Keiji: Development of Synthetic mRNAs Encoding Split Cytotoxic Proteins for Selective Cell Elimination Based on Specific Protein Detection PHARMACEUTICS. 2023.01; 15 (1): ( DOI )

  1. 中西秀之，位髙啓史: 指定された期間・細胞種において選択的に薬効を発揮するmRNA医薬のための翻訳制御技術 Drug Delivery System. 2022.07; 37 (3): 209-220.

  2. 中西秀之, 位髙啓史: 指定された期間・細胞種において選択的に薬効を発揮するmRNA医薬のための翻訳制御技術 Drug Delivery System. 2022.07; 37 (3): 209-220.

  3. Nakanishi Hideyuki, Itaka Keiji: Synthetic mRNA for ex vivo therapeutic applications DRUG METABOLISM AND PHARMACOKINETICS. 2022.06; 44 ( DOI )

  4. 中西秀之, 位髙啓史: mRNAワクチン・mRNA医薬は何を可能にするのか ファルマシア. 2022.05; 58 (5): 415-419. ( DOI )

  5. Nakanishi Hideyuki, Saito Hirohide, Itaka Keiji: Versatile Design of Intracellular Protein-Responsive Translational Regulation System for Synthetic mRNA ACS SYNTHETIC BIOLOGY. 2022.03; 11 (3): 1077-1085. ( DOI )

  1. 中西秀之, 位髙啓史: mRNA医薬・mRNAワクチンの基礎と応用 実験医学増刊「核酸医薬 本領を発揮する創薬モダリティ」. 2021.10; 39 (17):

  2. 中西秀之, 位髙啓史: mRNA医薬・mRNAワクチンの基礎と応用 実験医学増刊. 2021.10; 39 (17): 51-59.

  1. 中西秀之, 齊藤博英: 第9章 医科学 9.1 細胞システム制御 核酸科学ハンドブック. 2020.12;

  1. 位髙啓史、秋永士朗、井上貴雄: mRNA医薬開発の世界的動向 医薬品医療機器レギュラトリーサイエンス, PMDRS. 2019.05; 50 (5): 242-249.

  2. 位髙啓史: mRNA医薬の研究開発動向と将来展望 医薬ジャーナル. 2019.02; 55 (2): 627-632.

  1. 位髙啓史、福島雄大: mRNA医薬を用いた脳神経疾患の治療戦略 バイオマテリアル－生体材料－. 2018.06; 36 (3): 220-223.

  1. 福島 雄大, 今井 英明, 内田 智士, 中冨 浩文, 片岡 一則, 位高 啓史, 斉藤 延人: mRNAデリバリーによる虚血性神経細胞死治療　Enhancement of neuroprotective effect of astrocytes 脳循環代謝. 2017.11; 29 (1): 221. ( 医中誌 )

  2. 中西 秀之, 齊藤 博英: microRNA応答スイッチシステムによるヒト細胞状態の可視化と目的細胞の選別 バイオサイエンスとインダストリー. 2017.11; 75 (6): 488-494. ( 医中誌 )

  1. Nakanishi H, Higuchi Y, Kawakami S, Yamashita F, Hashida M: [Development and therapeutic application of transposon-based vectors]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2009.12; 129 (12): 1433-43. ( PubMed , DOI )

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