Hagihara, H; Shoji, H; Hattori, S; Sala, G; Takamiya, Y; Tanaka, M; Ihara, M; Shibutani, M; Hatada, I; Hori, K; Hoshino, M; Nakao, A; Mori, Y; Okabe, S; Matsushita, M; Urbach, A; Katayama, Y; Matsumoto, A; Nakayama, KI; Katori, S; Sato, T; Iwasato, T; Nakamura, H; Goshima, Y; Raveau, M; Tatsukawa, T; Yamakawa, K; Takahashi, N; Kasai, H; Inazawa, J; Nobuhisa, I; Kagawa, T; Taga, T; Darwish, M; Nishizono, H; Takao, K; Sapkota, K; Nakazawa, K; Takagi, T; Fujisawa, H; Sugimura, Y; Yamanishi, K; Rajagopal, L; Hannah, ND; Meltzer, HY; Yamamoto, T; Wakatsuki, S; Araki, T; Tabuchi, K; Numakawa, T; Kunugi, H; Huang, FL; Hayata-Takano, A; Hashimoto, H; Tamada, K; Takumi, T; Kasahara, T; Kato, T; Graef, IA; Crabtree, GR; Asaoka, N; Hatakama, H; Kaneko, S; Kohno, T; Hattori, M; Hoshiba, Y; Miyake, R; Obi-Nagata, K; Hayashi-Takagi, A; Becker, LJ; Yalcin, I; Hagino, Y; Kotajima-Murakami, H; Moriya, Y; Ikeda, K; Kim, H; Kaang, BK; Otabi, H; Yoshida, Y; Toyoda, A; Komiyama, NH; Grant, SGN; Ida-Eto, M; Narita, M; Matsumoto, KI; Okuda-Ashitaka, E; Ohmori, I; Shimada, T; Yamagata, K; Ageta, H; Tsuchida, K; Inokuchi, K; Sassa, T; Kihara, A; Fukasawa, M; Usuda, N; Katano, T; Tanaka, T; Yoshihara, Y; Igarashi, M; Hayashi, T; Ishikawa, K; Yamamoto, S; Nishimura, N; Nakada, K; Hirotsune, S; Egawa, K; Higashisaka, K; Tsutsumi, Y; Nishihara, S; Sugo, N; Yagi, T; Ueno, N; Yamamoto, T; Kubo, Y; Ohashi, R; Shiina, N; Shimizu, K; Higo-Yamamoto, S; Oishi, K; Mori, H; Furuse, T; Tamura, M; Shirakawa, H; Sato, DX; Inoue, YU; Inoue, T; Komine, Y; Yamamori, T; Sakimura, K; Miyakawa, T: Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment ELIFE. 2024.03; 12 ( PubMed , DOI )

Shiraishi K, Takahashi A, Momozawa Y, Daigo Y, Kaneko S, Kawaguchi T, Kunitoh H, Matsumoto S, Horinouchi H, Goto A, Honda T, Shimizu K, Torasawa M, Takayanagi D, Saito M, Saito A, Ohe Y, Watanabe SI, Goto K, Tsuboi M, Tsuchihara K, Takata S, Aoi T, Takano A, Kobayashi M, Miyagi Y, Tanaka K, Suzuki H, Maeda D, Yamaura T, Matsuda M, Shimada Y, Mizuno T, Sakamoto H, Yoshida T, Goto Y, Yoshida T, Yamaji T, Sonobe M, Toyooka S, Yoneda K, Masago K, Tanaka F, Hara M, Fuse N, Nishizuka SS, Motoi N, Sawada N, Nishida Y, Kumada K, Takeuchi K, Tanno K, Yatabe Y, Sunami K, Hishida T, Miyazaki Y, Ito H, Amemiya M, Totsuka H, Nakayama H, Yokose T, Ishigaki K, Nagashima T, Ohtaki Y, Imai K, Takasawa K, Minamiya Y, Kobayashi K, Okubo K, Wakai K, Shimizu A, Yamamoto M, Iwasaki M, Matsuda K, Inazawa J, Shiraishi Y, Nishikawa H, Murakami Y, Kubo M, Matsuda F, Kamatani Y, Hamamoto R, Matsuo K, Kohno T: Identification of telomere maintenance gene variations related to lung adenocarcinoma risk by genome-wide association and whole genome sequencing analyses. Cancer communications (London, England). 2023.10; 44 (2): 287-293. ( PubMed , DOI )

Honda T, Seto K, Endo S, Takemoto A, Tanimoto K, Kobayashi M, Kitano M, Sakakibara R, Mitsumura T, Ishibashi H, Inazawa J, Tanaka T, Miyazaki Y, Okubo K: The possibility of mutations of RAS signaling genes and/or TP53 in combination as a negative prognostic impact on pathological stage I non-small cell lung cancer. Cancer medicine. 2023.09; ( PubMed , DOI )

Uehara DT, Muramatsu T, Ishii S, Suzuki H, Fukushima K, Arasaki Y, Hayata T, Inazawa J, Ezura Y: Identification of a Biallelic Missense Variant in Gasdermin D (c.823G > C, p.Asp275His) in a Patient of Atypical Gorham-Stout Disease in a Consanguineous Family. JBMR plus. 2023.09; 7 (9): e10784. ( PubMed , DOI )

Yoshikawa R, Inoue J, Iwasaki R, Terauchi M, Fujii Y, Ohta M, Hasegawa T, Mizuno R, Mori T, Inazawa J: Therapeutic applications of local injection of hsa-miR-634 into canine spontaneous malignant melanoma tumors. Cancer gene therapy. 2023.08; 30 (11): 1524-1529. ( PubMed , DOI )

Tsukamoto Taku, Kinoshita Masaki, Yamada Kazuhiro, Ito Hodaka, Yamaguchi Toshikazu, Chinen Yoshiaki, Mizutani Shinsuke, Fujino Takahiro, Kobayashi Tsutomu, Shimura Yuji, Inazawa Johji, Kuroda Junya: 多発性骨髄腫における3種類のIGH遺伝子の転座に対するイメージングフローサイトメトリを用いたマルチプレックスFISH(Imaging flow cytometry-based multiplex FISH for three IGH translocations in multiple myeloma) Journal of Human Genetics. 2023.07; 68 (7): 507-514. ( 医中誌 )

Tsukamoto T, Kinoshita M, Yamada K, Ito H, Yamaguchi T, Chinen Y, Mizutani S, Fujino T, Kobayashi T, Shimura Y, Inazawa J, Kuroda J: Imaging flow cytometry-based multiplex FISH for three IGH translocations in multiple myeloma. Journal of human genetics. 2023.07; 68 (7): 507-514. ( PubMed , DOI )

Shin Yujeong, Wada Kanae, Tsuchida Yumi, Ijbara Manhal, Ikeda Masaomi, Takahashi Hidekazu, Iwamoto Tsutomu: Wear behavior of materials for additive manufacturing after simulated occlusion of deciduous dentition JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS. 2023.02; 138 105627. ( PubMed , DOI )

Uno Y, Matsubara K, Inoue J, Inazawa J, Shinohara A, Koshimoto C, Ichiyanagi K, Matsuda Y: Diversity and Evolution of Highly Repetitive DNA Sequences Constituting Chromosome Site-Specific Heterochromatin in Two Gerbillinae Species. Cytogenetic and genome research. 2023; 163 (1-2): 42-51. ( PubMed , DOI )

Tran PX, Inoue J, Harada H, Inazawa J: Potential for reversing miR-634-mediated cytoprotective processes to improve efficacy of chemotherapy against oral squamous cell carcinoma. Mol Ther Oncolytics. 2022.03; 24 897-908. ( PubMed , DOI )

Akamatsu S, Terada N, Takata R, Kinoshita H, Shimatani K, Momozawa Y, Yamamoto M, Tada H, Kawamorita N, Narita S, Kato T, Nitta M, Kandori S, Koike Y, Inazawa J, Kimura T, Kimura H, Kojima T, Terachi T, Sugimoto M, Habuchi T, Arai Y, Yamamoto S, Matsuda T, Obara W, Kamoto T, Inoue T, Nakagawa H, Ogawa O: Clinical Utility of Germline Genetic Testing in Japanese Men Undergoing Prostate Biopsy. JNCI cancer spectrum. 2022.02; 6 (1): ( PubMed , DOI )

Zhang Menghua, Sugita Itsuki, Komura Daisuke, Katoh Hiroto, Shimada Shu, Inazawa Johji, Tanaka Shinji, Ishikawa Shumpei: 瀰漫性胃腺癌のマウスモデルのゲノムの全体像(Genomic Iandscape of a mouse model of diffuse-type gastric adenocarcinoma) Gastric Cancer. 2022.01; 25 (1): 83-95. ( 医中誌 )

Takemoto Akira, Tanimoto Kousuke, Mori Seiichi, Inoue Jun, Fujiwara Naoto, Noda Tetsuo, Inazawa Johji: 統合的ゲノムワイド解析により日本人食道扁平上皮癌の転写異常が明らかになる(Integrative genome-wide analyses reveal the transcriptional aberrations in Japanese esophageal squamous cell carcinoma) Cancer Science. 2021.10; 112 (10): 4377-4392. ( 医中誌 )

Takemoto A, Tanimoto K, Mori S, Inoue J, Fujiwara N, Noda T, Inazawa J: Integrative genome-wide analyses reveal the transcriptional aberrations in Japanese esophageal squamous cell carcinoma. Cancer science. 2021.10; 112 (10): 4377-4392. ( PubMed , DOI )

Inoue Jun, Inazawa Johji: 【Cancer Genomics】がん関連miRNAsとそれらの治療に対する潜在能力(【Cancer Genomcs】Cancer-associated miRNAs and their therapeutic potential) Journal of Human Genetics. 2021.09; 66 (9): 937-945. ( 医中誌 )

Inazawa J, Miki Y, Nakamura Y: Integrative cancer genomics in the era of precision cancer medicine. Journal of human genetics. 2021.09; 66 (9): 843. ( PubMed , DOI )

Inoue J, Inazawa J: Cancer-associated miRNAs and their therapeutic potential. Journal of human genetics. 2021.09; 66 (9): 937-945. ( PubMed , DOI )

Liu C, Gen Y, Tanimoto K, Muramatsu T, Inoue J, Inazawa J: Concurrent targeting of MAP3K3 and BRD4 by miR-3140-3p overcomes acquired resistance to BET inhibitors in neuroblastoma cells. Molecular therapy. Nucleic acids. 2021.09; 25 83-92. ( PubMed , DOI )

Gen Y, Muramatsu T, Inoue J, Inazawa J: miR-766-5p targets super-enhancers by downregulating CBP and BRD4. Cancer research. 2021.08; ( PubMed , DOI )

Zhang M, Sugita I, Komura D, Katoh H, Shimada S, Inazawa J, Tanaka S, Ishikawa S: Genomic landscape of a mouse model of diffuse-type gastric adenocarcinoma. Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association. 2021.08; ( PubMed , DOI )

Uehara DT, Mitsubuchi H, Inazawa J: A missense variant in NUF2, a component of the kinetochore NDC80 complex, causes impaired chromosome segregation and aneuploidy associated with microcephaly and short stature. Human genetics. 2021.07; 140 (7): 1047-1060. ( PubMed , DOI )

Kishikawa M, Inoue J, Hamamoto H, Kobayashi K, Asakage T, Inazawa J: Augmentation of lenvatinib efficacy by topical treatment of miR-634 ointment in anaplastic thyroid cancer. Biochemistry and biophysics reports. 2021.07; 26 101009. ( PubMed , DOI )

Inoue Jun, Kishikawa Masahiro, Tsuda Hitoshi, Nakajima Yasuaki, Asakage Takahiro, Inazawa Johji: 食道扁平上皮癌に対する代謝標的治療においてPDHX遺伝子の特定(Identification of PDHX as a metabolic target for esophageal squamous cell carcinoma) Cancer Science. 2021.07; 112 (7): 2792-2802. ( 医中誌 )

Inoue J, Kishikawa M, Tsuda H, Nakajima Y, Asakage T, Inazawa J: Identification of PDHX as a metabolic target for esophageal squamous cell carcinoma. Cancer science. 2021.07; 112 (7): 2792-2802. ( PubMed , DOI )

Xu B, Muramatsu T, Inazawa J: Suppression of MET Signaling Mediated by Pitavastatin and Capmatinib Inhibits Oral and Esophageal Cancer Cell Growth. Molecular cancer research : MCR. 2021.04; 19 (4): 585-597. ( PubMed , DOI )

Koichi Nishino, Yasuhiro Yoshimatsu, Tomoki Muramatsu, Yasuhito Sekimoto, Keiko Mitani, Etsuko Kobayashi, Shouichi Okamoto, Hiroki Ebana, Yoshinori Okada, Masatoshi Kurihara, Kenji Suzuki, Johji Inazawa, Kazuhisa Takahashi, Tetsuro Watabe, Kuniaki Seyama: Isolation and characterisation of lymphatic endothelial cells from lung tissues affected by lymphangioleiomyomatosis. Sci Rep. 2021.04; 11 (1): 8406. ( PubMed , DOI )

Gen Yasuyuki, Inazawa Johji: Nucleic acid therapeutics using a novel tumor-suppressive microRNA targeting MYC pathway CANCER SCIENCE. 2021.02; 112 647.

Muramatsu Tomoki, Xu Bo, Inazawa Johji: Pitavastatin inhibits the tumor growth through the suppression of AKT and ERK signals in oral and esophageal cancer CANCER SCIENCE. 2021.02; 112 285.

Takata Ryo, Akamatsu Shusuke, Nakagawa Hidewaki, Takahashi Atsushi, Egawa Shin, Kamatani Yoichiro, Inazawa Johji, Ogawa Osamu, Obara Wataru: Identification of twelve new susceptibility loci and polygenic risk for prostate cancer in Japanese population CANCER SCIENCE. 2021.02; 112 321.

Inoue Jun, Kishikawa Masahiro, Asakage Takahiro, Inazawa Johji: Exploring metabolic therapeutic targets for esophageal squamous cell carcinoma CANCER SCIENCE. 2021.02; 112 385.

Inazawa Johji: Genomics/Genetics in the era of Precision Cancer Medicine (PCM) CANCER SCIENCE. 2021.02; 112 233.

Liu Chang, Gen Yasuyuki, Inazawa Johji: miR-3140 suppressed tumor cell growth in neuroblastoma by targeting BRD4-MYCN pathway CANCER SCIENCE. 2021.02; 112 579.

Shigeru Watanabe, Yukiko Yamamura, Aiko Hoshiai, Shiho Morishita, Aiko Machiya, Satoru Matsuda, Takahiro Shimojima and Iwai Tohnai: Salivary volume in the mouth immediately before and after swallowing in children Dental, Oral and Maxillofacial Research. 2021.01; 7 ( DOI )

Beck DB, Basar MA, Asmar AJ, Thompson JJ, Oda H, Uehara DT, Saida K, Pajusalu S, Talvik I, D'Souza P, Bodurtha J, Mu W, Barañano KW, Miyake N, Wang R, Kempers M, Tamada T, Nishimura Y, Okada S, Kosho T, Dale R, Mitra A, Macnamara E, Undiagnosed Diseases Network., Matsumoto N, Inazawa J, Walkiewicz M, Õunap K, Tifft CJ, Aksentijevich I, Kastner DL, Rocha PP, Werner A: Linkage-specific deubiquitylation by OTUD5 defines an embryonic pathway intolerant to genomic variation. Science advances. 2021.01; 7 (4): ( PubMed , DOI )

Inoue J, Fujiwara K, Hamamoto H, Kobayashi K, Inazawa J: Improving the Efficacy of EGFR Inhibitors by Topical Treatment of Cutaneous Squamous Cell Carcinoma with miR-634 Ointment. Molecular therapy oncolytics. 2020.12; 19 294-307. ( PubMed , DOI )

Taku Sato, Shun Ishikawa, Jumpei Asano, Hirona Yamamoto, Masayuki Fujii, Toshiro Sato, Kouhei Yamamoto, Keisuke Kitagaki, Takumi Akashi, Ryuichi Okamoto, Toshiaki Ohteki: Regulated IFN signalling preserves the stemness of intestinal stem cells by restricting differentiation into secretory-cell lineages. Nat Cell Biol. 2020.08; 22 (8): 919-926. ( PubMed , DOI )

Ishigaki K, Akiyama M, Kanai M, Takahashi A, Kawakami E, Sugishita H, Sakaue S, Matoba N, Low SK, Okada Y, Terao C, Amariuta T, Gazal S, Kochi Y, Horikoshi M, Suzuki K, Ito K, Koyama S, Ozaki K, Niida S, Sakata Y, Sakata Y, Kohno T, Shiraishi K, Momozawa Y, Hirata M, Matsuda K, Ikeda M, Iwata N, Ikegawa S, Kou I, Tanaka T, Nakagawa H, Suzuki A, Hirota T, Tamari M, Chayama K, Miki D, Mori M, Nagayama S, Daigo Y, Miki Y, Katagiri T, Ogawa O, Obara W, Ito H, Yoshida T, Imoto I, Takahashi T, Tanikawa C, Suzuki T, Sinozaki N, Minami S, Yamaguchi H, Asai S, Takahashi Y, Yamaji K, Takahashi K, Fujioka T, Takata R, Yanai H, Masumoto A, Koretsune Y, Kutsumi H, Higashiyama M, Murayama S, Minegishi N, Suzuki K, Tanno K, Shimizu A, Yamaji T, Iwasaki M, Sawada N, Uemura H, Tanaka K, Naito M, Sasaki M, Wakai K, Tsugane S, Yamamoto M, Yamamoto K, Murakami Y, Nakamura Y, Raychaudhuri S, Inazawa J, Yamauchi T, Kadowaki T, Kubo M, Kamatani Y: Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Nature genetics. 2020.07; 52 (7): 669-679. ( PubMed , DOI )

Takagawa Y, Gen Y, Muramatsu T, Tanimoto K, Inoue J, Harada H, Inazawa J: miR-1293, a Candidate for miRNA-Based Cancer Therapeutics, Simultaneously Targets BRD4 and the DNA Repair Pathway. Molecular therapy : the journal of the American Society of Gene Therapy. 2020.06; 28 (6): 1494-1505. ( PubMed , DOI )

Kanayama M, Izumi Y, Yamauchi Y, Kuroda S, Shin T, Ishikawa S, Sato T, Kajita M, Ohteki T: CD86-based analysis enables observation of bona fide hematopoietic responses. Blood. 2020.05; ( PubMed , DOI )

Taku Sato, Miwako Sase, Shun Ishikawa, Mihoko Kajita, Jumpei Asano, Toshiro Sato, Yoshiyuki Mori, Toshiaki Ohteki: Characterization of radioresistant epithelial stem cell heterogeneity in the damaged mouse intestine. Sci Rep. 2020.05; 10 (1): 8308. ( PubMed , DOI )

Takahashi Kenta, Gen Yasuyuki, Tanimoto Kousuke, Kudo Atsushi, Oshima Noriko, Ban Daisuke, Takemoto Akira, Onishi Iichiro, Kumaki Yuichi, Yokobori Junko, Takamine Eriko, Kano Yoshihito, Miyake Satoshi, Miyasaka Naoyuki, Tanabe Minoru, Inazawa Johji, Ikeda Sadakatsu: Clinical impact of hemizygous deletion detection and panel-size in comprehensive genomic profiling. JOURNAL OF CLINICAL ONCOLOGY. 2020.05; 38 (15):

Gokita K, Inoue J, Ishihara H, Kojima K, Inazawa J: Therapeutic Potential of LNP-Mediated Delivery of miR-634 for Cancer Therapy. Molecular therapy. Nucleic acids. 2020.03; 19 330-338. ( PubMed , DOI )

Matsukawa T, Yamamoto T, Honda A, Toya T, Ishiura H, Mitsui J, Tanaka M, Hao A, Shinohara A, Ogura M, Kataoka K, Seo S, Kumano K, Hosoi M, Narukawa K, Yasunaga M, Maki H, Ichikawa M, Nannya Y, Imai Y, Takahashi T, Takahashi Y, Nagasako Y, Yasaka K, Mano KK, Matsukawa MK, Miyagawa T, Hamada M, Sakuishi K, Hayashi T, Iwata A, Terao Y, Shimizu J, Goto J, Mori H, Kunimatsu A, Aoki S, Hayashi S, Nakamura F, Arai S, Momma K, Ogata K, Yoshida T, Abe O, Inazawa J, Toda T, Kurokawa M, Tsuji S: Clinical efficacy of haematopoietic stem cell transplantation for adult adrenoleukodystrophy. Brain communications. 2020; 2 (1): fcz048. ( PubMed , DOI )

Tanimoto K, Muramatsu T, Inazawa J: Massive computational identification of somatic variants in exonic splicing enhancers using The Cancer Genome Atlas. Cancer medicine. 2019.12; 8 (17): 7372-7384. ( PubMed , DOI )

Hirabayashi Kyoko, Uehara Daniela Tiaki, Abe Hidetoshi, Ishii Atsushi, Moriyama Keiji, Hirose Shinichi, Inazawa Johji: Copy number variation analysis in 83 children with early-onset developmental and epileptic encephalopathy after targeted resequencing of a 109-epilepsy gene panel(和訳中) Journal of Human Genetics. 2019.11; 64 (11): 1097-1106. ( 医中誌 )

Hirabayashi K, Uehara DT, Abe H, Ishii A, Moriyama K, Hirose S, Inazawa J: Copy number variation analysis in 83 children with early-onset developmental and epileptic encephalopathy after targeted resequencing of a 109-epilepsy gene panel. Journal of human genetics. 2019.11; 64 (11): 1097-1106. ( PubMed , DOI )

Low SK, Chin YM, Ito H, Matsuo K, Tanikawa C, Matsuda K, Saito H, Sakurai-Yageta M, Nakaya N, Shimizu A, Nishizuka SS, Yamaji T, Sawada N, Iwasaki M, Tsugane S, Takezaki T, Suzuki S, Naito M, Wakai K, Kamatani Y, Momozawa Y, Murakami Y, Inazawa J, Nakamura Y, Kubo M, Katagiri T, Miki Y: Identification of two novel breast cancer loci through large-scale genome-wide association study in the Japanese population. Scientific reports. 2019.11; 9 (1): 17332. ( PubMed , DOI )

Takata R, Takahashi A, Fujita M, Momozawa Y, Saunders EJ, Yamada H, Maejima K, Nakano K, Nishida Y, Hishida A, Matsuo K, Wakai K, Yamaji T, Sawada N, Iwasaki M, Tsugane S, Sasaki M, Shimizu A, Tanno K, Minegishi N, Suzuki K, Matsuda K, Kubo M, Inazawa J, Egawa S, Haiman CA, Ogawa O, Obara W, Kamatani Y, Akamatsu S, Nakagawa H: 12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population. Nature communications. 2019.09; 10 (1): 4422. ( PubMed , DOI )

Akatsu Y, Takahashi N, Yoshimatsu Y, Kimuro S, Muramatsu T, Katsura A, Maishi N, Suzuki HI, Inazawa J, Hida K, Miyazono K, Watabe T: Fibroblast growth factor signals regulate transforming growth factor-β-induced endothelial-to-myofibroblast transition of tumor endothelial cells via Elk1. Mol. Oncol.. 2019.08; 13 (8): 1706-1724. ( PubMed , DOI )

Kikuchi-Koike R, Nagasaka K, Tsuda H, Ishii Y, Sakamoto M, Kikuchi Y, Fukui S, Miyagawa Y, Hiraike H, Kobayashi T, Kinoshita T, Kanai Y, Shibata T, Imoto I, Inazawa J, Matsubara O, Ayabe T: Array comparative genomic hybridization analysis discloses chromosome copy number alterations as indicators of patient outcome in lymph node-negative breast cancer. BMC cancer. 2019.05; 19 (1): 521. ( PubMed , DOI )

Tanikawa Chizu, Kamatani Yoichiro, Toyoshima Osamu, Sakamoto Hiromi, Ito Hidemi, Takahashi Atsushi, Momozawa Yukihide, Hirata Makoto, Fuse Nobuo, Takai-Igarashi Takako, Shimizu Atsushi, Sasaki Makoto, Yamaji Taiki, Sawada Norie, Iwasaki Motoki, Tsugane Shoichiro, Naito Mariko, Hishida Asahi, Wakai Kenji, Furusyo Norihiro, Murakami Yoshinori, Nakamura Yusuke, Imoto Issei, Inazawa Johji, Oze Isao, Sato Naomi, Tanioka Fumihiko, Sugimura Haruhiko, Hirose Hiroshi, Yoshida Teruhiko, Matsuo Keitaro, Kubo Michiaki, Matsuda Koichi: ゲノムワイド関連解析により12q24.11-12および20q11.21に胃癌感受性遺伝子座が同定される(Genome-wide association study identifies gastric cancer susceptibility loci at 12q24.11-12 and 20q11.21) Cancer Science. 2018.12; 109 (12): 4015-4024. ( 医中誌 )

Takagawa Yuki, Gen Yasuyuki, Muramatsu Tomoki, Harada Hiroyuki, Inazawa Johji: Exploring novel tumor suppressive microRNAs in OSCC CANCER SCIENCE. 2018.12; 109 1083.

Inazawa Johji: From genomic alterations to target genes for cancer therapy; miRNA therapeutics has emerged as a promising strategy CANCER SCIENCE. 2018.12; 109 1079.

Tanikawa C, Kamatani Y, Toyoshima O, Sakamoto H, Ito H, Takahashi A, Momozawa Y, Hirata M, Fuse N, Takai-Igarashi T, Shimizu A, Sasaki M, Yamaji T, Sawada N, Iwasaki M, Tsugane S, Naito M, Hishida A, Wakai K, Furusyo N, Murakami Y, Nakamura Y, Imoto I, Inazawa J, Oze I, Sato N, Tanioka F, Sugimura H, Hirose H, Yoshida T, Matsuo K, Kubo M, Matsuda K: Genome-wide association study identifies gastric cancer susceptibility loci at 12q24.11-12 and 20q11.21. Cancer science. 2018.12; 109 (12): 4015-4024. ( PubMed , DOI )

Inoue Jun, Furusawa Akiko, Miyamoto Morikazu, Takano Masashi, Tsuda Hitoshi, Song Yong Sang, Aoki Daisuke, Miyasaka Naoyuki, Inazawa Johji: Ovarian cancer therapeutic potential of glutamine depletion based on GS expression CANCER SCIENCE. 2018.12; 109 330.

Takata Ryo, Akamatsu Shusuke, Nakagawa Hidewaki, Takahashi Atsushi, Terada Naoki, Kato Yoichiro, Kanehira Mitsugu, Sugimura Jun, Inazawa Johji, Ogawa Osamu, Obara Wataru: Identification of fourteen new susceptibility loci for prostate cancer in the Japanese population CANCER SCIENCE. 2018.12; 109 1142.

Gokita Kentaro, Inoue Jun, Ishihara Hiroshi, Kojima Kazuyuki, Inazawa Johji: Therapeutic potential of LNP-mediated delivery of miR-634 for cancer therapy CANCER SCIENCE. 2018.12; 109 253.

Kishikawa Masahiro, Inoue Jun, Hamamoto Hidetoshi, Kobayashi Katsunori, Fujiwara Kyoko, Asakage Takahiro, Inazawa Johji: Therapeutic potential of the topical treatment of miR-634 ointment for skin cancer CANCER SCIENCE. 2018.12; 109 1012.

Gen Yasuyuki, Inoue Jun, Inazawa Johji: The exploration of miRNAs that induce cell death in p53-inactive cancer cells using functional-miRNA screening CANCER SCIENCE. 2018.12; 109 395.

Sato Taku, Muramatsu Tomoki, Tanabe Minoru, Inazawa Johji: 膵癌細胞株由来の循環腫瘍細胞系で誘導したトランスフォーミング成長因子βの同定と特性評価(Identification and characterization of transforming growth factor beta-induced in circulating tumor cell subline from pancreatic cancer cell line) Cancer Science. 2018.11; 109 (11): 3623-3633. ( 医中誌 )

Sato T, Muramatsu T, Tanabe M, Inazawa J: Identification and characterization of transforming growth factor beta-induced in circulating tumor cell subline from pancreatic cancer cell line. Cancer science. 2018.11; 109 (11): 3623-3633. ( PubMed , DOI )

Tanikawa C, Kamatani Y, Takahashi A, Momozawa Y, Leveque K, Nagayama S, Mimori K, Mori M, Ishii H, Inazawa J, Yasuda J, Tsuboi A, Shimizu A, Sasaki M, Yamaji T, Sawada N, Iwasaki M, Tsugane S, Naito M, Wakai K, Koyama T, Takezaki T, Yuji K, Murakami Y, Nakamura Y, Kubo M, Matsuda K: GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12. Carcinogenesis. 2018.05; 39 (5): 652-660. ( PubMed , DOI )

Tonouchi E, Gen Y, Muramatsu T, Hiramoto H, Tanimoto K, Inoue J, Inazawa J: Publisher Correction: miR-3140 suppresses tumor cell growth by targeting BRD4 via its coding sequence and downregulates the BRD4-NUT fusion oncoprotein. Scientific reports. 2018.04; 8 (1): 6769. ( PubMed , DOI )

Akiko Furusawa, Morikazu Miyamoto, Masashi Takano, Hitoshi Tsuda, Yong Sang Song, Daisuke Aoki, Naoyuki Miyasaka, Johji Inazawa, Jun Inoue: Ovarian cancer therapeutic potential of glutamine depletion based on GS expression. Carcinogenesis. 2018.04; ( PubMed , DOI )

Tonouchi E, Gen Y, Muramatsu T, Hiramoto H, Tanimoto K, Inoue J, Inazawa J: miR-3140 suppresses tumor cell growth by targeting BRD4 via its coding sequence and downregulates the BRD4-NUT fusion oncoprotein SCIENTIFIC REPORTS. 2018.03; 8 (1): 4482. ( PubMed , DOI )

Chinen Y, Nakamura S, Ganaha A, Hayashi S, Inazawa J, Yanagi K, Nakanishi K, Kaname T, Naritomi K: Mild prominence of the Sylvian fissure in a Bainbridge-Ropers syndrome patient with a novel frameshift variant in ASXL3. Clinical case reports. 2018.02; 6 (2): 330-336. ( PubMed , DOI )

Kanai Y, Nishihara H, Miyagi Y, Tsuruyama T, Taguchi K, Katoh H, Takeuchi T, Gotoh M, Kuramoto J, Arai E, Ojima H, Shibuya A, Yoshida T, Akahane T, Kasajima R, Morita KI, Inazawa J, Sasaki T, Fukayama M, Oda Y: The Japanese Society of Pathology Guidelines on the handling of pathological tissue samples for genomic research: Standard operating procedures based on empirical analyses. Pathology international. 2018.02; 68 (2): 63-90. ( PubMed , DOI )

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Akdemir Burak, Nakajima Yasuaki, Inazawa Johji, Inoue Jun: High expression of miR-432-3p is involved in NRF2 stabilization by directly targeting KEAP1 CANCER SCIENCE. 2018.01; 109 466.

Furusawa Akiko, Inoue Jun, Tsuda Hitoshi, Miyasaka Naoyuki, Inazawa Johji: Differential requirement of amino acids on cell survival of ovarian cancer cells CANCER SCIENCE. 2018.01; 109 128.

Tonouchi Erina, Muramatsu Tomoki, Gen Yasuyuki, Hiramoto Hidekazu, Inazawa Johji: Function-based microRNA library screening identified a novel tumor suppressive miRNA regulating BRD4, a BET family gene CANCER SCIENCE. 2018.01; 109 597.

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Hiramoto Hidekazu, Muramatsu Tomoki, Ichikawa Daisuke, Otsuji Eigo, Inazawa Johji: miR-509-5p and miR-1243 inhibit epithelial-mesenchymal transition in pancreatic cancer. CANCER SCIENCE. 2018.01; 109 601.

Gen Yasuyuki, Inoue Jun, Inazawa Johji: The exploration of miRNAs that induce cell death in p53-inactive cancer cells using functional-miRNA screening CANCER SCIENCE. 2018.01; 109 598.

Kevin Y Urayama, Masatoshi Takagi, Takahisa Kawaguchi, Keitaro Matsuo, Yoichi Tanaka, Yoko Ayukawa, Yuki Arakawa, Daisuke Hasegawa, Yuki Yuza, Takashi Kaneko, Yasushi Noguchi, Yuichi Taneyama, Setsuo Ota, Takeshi Inukai, Masakatsu Yanagimachi, Dai Keino, Kazutoshi Koike, Daisuke Toyama, Yozo Nakazawa, Hidemitsu Kurosawa, Kozue Nakamura, Koichi Moriwaki, Hiroaki Goto, Yujin Sekinaka, Daisuke Morita, Motohiro Kato, Junko Takita, Toshihiro Tanaka, Johji Inazawa, Katsuyoshi Koh, Yasushi Ishida, Akira Ohara, Shuki Mizutani, Fumihiko Matsuda, Atsushi Manabe: Regional evaluation of childhood acute lymphoblastic leukemia genetic susceptibility loci among Japanese. Sci Rep. 2018.01; 8 (1): 789. ( PubMed , DOI )

Burak Akdemir, Yasuaki Nakajima, Johji Inazawa, Jun Inoue: miR-432 Induces NRF2 Stabilization by Directly Targeting KEAP1. Mol. Cancer Res.. 2017.11; 15 (11): 1570-1578. ( PubMed , DOI )

Hiramoto Hidekazu, Muramatsu Tomoki, Ichikawa Daisuke, Tanimoto Kousuke, Komatsu Syuhei, Yasukawa Satoru, Otsuji Eigo, Inazawa Johji: Exploring Epithelial-Mesenchymal Transition: Suppressive miRNAs Using Combination of Cell-Based Reporter System and miRNA Library JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS. 2017.10; 225 (4): E121-E122.

Matsukawa T., Mitsui J., Ishiura H., Takahashi Y., Tanaka M., Hayashi S., Goto J., Inazawa J., Tsuji S.: Mutational analysis of abcd1 in 86 adrenoleukodystrophy patients, including identification of complex mutations JOURNAL OF THE NEUROLOGICAL SCIENCES. 2017.10; 381 159. ( DOI )

Shin Hayashi, Daniela Tiaki Uehara, Kousuke Tanimoto, Seiji Mizuno, Yasutsugu Chinen, Shinobu Fukumura, Jun-Ichi Takanashi, Hitoshi Osaka, Nobuhiko Okamoto, Johji Inazawa: Comprehensive investigation of CASK mutations and other genetic etiologies in 41 patients with intellectual disability and microcephaly with pontine and cerebellar hypoplasia (MICPCH). PLoS ONE. 2017.08; 12 (8): e0181791. ( PubMed , DOI )

H Takahashi, J Inoue, K Sakaguchi, M Takagi, S Mizutani, J Inazawa: Autophagy is required for cell survival under L-asparaginase-induced metabolic stress in acute lymphoblastic leukemia cells. Oncogene. 2017.07; 36 (30): 4267-4276. ( PubMed , DOI )

Hidekazu Hiramoto, Tomoki Muramatsu, Daisuke Ichikawa, Kousuke Tanimoto, Satoru Yasukawa, Eigo Otsuji, Johji Inazawa: miR-509-5p and miR-1243 increase the sensitivity to gemcitabine by inhibiting epithelial-mesenchymal transition in pancreatic cancer. Sci Rep. 2017.06; 7 (1): 4002. ( PubMed , DOI )

Hiroaki Nagata, Ken-Ichi Kozaki, Tomoki Muramatsu, Hidekazu Hiramoto, Kousuke Tanimoto, Naoto Fujiwara, Seiya Imoto, Daisuke Ichikawa, Eigo Otsuji, Satoru Miyano, Tatsuyuki Kawano, Johji Inazawa: Genome-wide screening of DNA methylation associated with lymph node metastasis in esophageal squamous cell carcinoma. Oncotarget. 2017.06; 8 (23): 37740-37750. ( PubMed , DOI )

Masafumi Okuda, Jun Inoue, Naoto Fujiwara, Tatsuyuki Kawano, Johji Inazawa: Subcloning and characterization of highly metastatic cells derived from human esophageal squamous cell carcinoma KYSE150 cells by in vivo selection. Oncotarget. 2017.05; 8 (21): 34670-34677. ( PubMed , DOI )

Oikawa Yu, Morita Kei-ichi, Kayamori Kou, Tanimoto Kousuke, Sakamoto Kei, Katoh Hiroto, Ishikawa Shumpei, Inazawa Johji, Harada Hiroyuki: 口腔扁平上皮癌患者では受容体チロシンキナーゼの増幅により遠隔転移が予測される(Receptor tyrosine kinase amplification is predictive of distant metastasis in patients with oral squamous cell carcinoma) Cancer Science. 2017.02; 108 (2): 256-266. ( 医中誌 )

Yu Oikawa, Kei-Ichi Morita, Kou Kayamori, Kousuke Tanimoto, Kei Sakamoto, Hiroto Katoh, Shumpei Ishikawa, Johji Inazawa, Hiroyuki Harada: Receptor tyrosine kinase amplification is predictive of distant metastasis in patients with oral squamous cell carcinoma. Cancer Sci.. 2017.02; 108 (2): 256-266. ( PubMed , DOI )

Sujata Sakha, Tomoki Muramatsu, Koji Ueda, Johji Inazawa: Exosomal microRNA miR-1246 induces cell motility and invasion through the regulation of DENND2D in oral squamous cell carcinoma. Sci Rep. 2016.12; 6 38750. ( PubMed , DOI )

Tsasan Tumurkhuu, Takeo Fujiwara, Yuko Komazaki, Yoko Kawaguchi, Toshihiro Tanaka, Johji Inazawa, Ganjargal Ganburged, Amarsaikhan Bazar, Takuya Ogawa, Keiji Moriyama: Association between maternal education and malocclusion in Mongolian adolescents: a cross-sectional study. BMJ Open. 2016.11; 6 (11): e012283. ( PubMed , DOI )

Tumurkhuu T, Fujiwara T, Komazaki Y, Kawaguchi Y, Tanaka T, Inazawa J, Ganburged G, Bazar A, Ogawa T, Moriyama K: Association between maternal education and malocclusion in Mongolian adolescents: a cross-sectional study. BMJ Open. 2016.11; 6 (11): e012283. ( PubMed , DOI )

Kouya Shiraishi, Yukinori Okada, Atsushi Takahashi, Yoichiro Kamatani, Yukihide Momozawa, Kyota Ashikawa, Hideo Kunitoh, Shingo Matsumoto, Atsushi Takano, Kimihiro Shimizu, Akiteru Goto, Koji Tsuta, Shun-Ichi Watanabe, Yuichiro Ohe, Yukio Watanabe, Yasushi Goto, Hiroshi Nokihara, Koh Furuta, Akihiko Yoshida, Koichi Goto, Tomoyuki Hishida, Masahiro Tsuboi, Katsuya Tsuchihara, Yohei Miyagi, Haruhiko Nakayama, Tomoyuki Yokose, Kazumi Tanaka, Toshiteru Nagashima, Yoichi Ohtaki, Daichi Maeda, Kazuhiro Imai, Yoshihiro Minamiya, Hiromi Sakamoto, Akira Saito, Yoko Shimada, Kuniko Sunami, Motonobu Saito, Johji Inazawa, Yusuke Nakamura, Teruhiko Yoshida, Jun Yokota, Fumihiko Matsuda, Keitaro Matsuo, Yataro Daigo, Michiaki Kubo, Takashi Kohno: Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma. Nat Commun. 2016.08; 7 12451. ( PubMed , DOI )

Nobuaki Ozawa, Haruhiko Sago, Kentaro Matsuoka, Tetsuo Maruyama, Ohsuke Migita, Yoshinori Aizu, Johji Inazawa: Cytogenetic analysis of spontaneously discharged products of conception by array-based comparative genomic hybridization. Springerplus. 2016.06; 5 (1): 874. ( PubMed , DOI )

Michelle Nuylan, Tatsuyuki Kawano, Johji Inazawa, Jun Inoue: Down-regulation of LAPTM5 in human cancer cells. Oncotarget. 2016.04; 7 (19): 28320-8. ( PubMed , DOI )

T Muramatsu, K-I Kozaki, S Imoto, R Yamaguchi, H Tsuda, T Kawano, N Fujiwara, M Morishita, S Miyano, J Inazawa: The hypusine cascade promotes cancer progression and metastasis through the regulation of RhoA in squamous cell carcinoma. Oncogene. 2016.04; ( PubMed , DOI )

Daniela Tiaki Uehara, Shin Hayashi, Nobuhiko Okamoto, Seiji Mizuno, Yasutsugu Chinen, Rika Kosaki, Tomoki Kosho, Kenji Kurosawa, Hiroshi Matsumoto, Hiroshi Mitsubuchi, Hironao Numabe, Shinji Saitoh, Yoshio Makita, Akira Hata, Issei Imoto, Johji Inazawa: SNP array screening of cryptic genomic imbalances in 450 Japanese subjects with intellectual disability and multiple congenital anomalies previously negative for large rearrangements. J. Hum. Genet.. 2016.04; 61 (4): 335-343. ( PubMed , DOI )

Genki Sudo, Tetsushi Kagawa, Yasuhiro Kokubu, Johji Inazawa, Tetsuya Taga: Increase in GFAP-positive astrocytes in histone demethylase GASC1/KDM4C/JMJD2C hypomorphic mutant mice. Genes Cells. 2016.03; 21 (3): 218-225. ( PubMed , DOI )

Maki Morishita, Tomoki Muramatsu, Yumiko Suto, Momoki Hirai, Teruaki Konishi, Shin Hayashi, Daichi Shigemizu, Tatsuhiko Tsunoda, Keiji Moriyama, Johji Inazawa: Chromothripsis-like chromosomal rearrangements induced by ionizing radiation using proton microbeam irradiation system. Oncotarget. 2016.03; 7 (9): 10182-10192. ( PubMed , DOI )

Okada Yukinori, Muramatsu Tomoki, Suita Naomasa, Kanai Masahiro, Kawakami Eiryo, Iotchkova Valentina, Soranzo Nicole, Inazawa Johji, Tanaka Toshihiro: Significant impact of miRNA-target gene networks on genetics of human complex traits. Sci Rep. 2016; 6 22223. ( PubMed , DOI )

Yumi Ozaki, Kyoko Fujiwara, Maki Ikeda, Toshinori Ozaki, Tadashi Terui, Masayoshi Soma, Johji Inazawa, Hiroki Nagase: The oncogenic role of GASC1 in chemically induced mouse skin cancer. Mamm. Genome. 2015.12; 26 (11-12): 591-597. ( PubMed , DOI )

Yoshimitsu Yanaka, Tomoki Muramatsu, Hiroyuki Uetake, Ken-ichi Kozaki, Johji Inazawa: miR-544a induces epithelial-mesenchymal transition through the activation of WNT signaling pathway in gastric cancer. Carcinogenesis. 2015.11; 36 (11): 1363-1371. ( PubMed , DOI )

Morita K, Naruto T, Tanimoto K, Yasukawa C, Oikawa Y, Masuda K, Imoto I, Inazawa J, Omura K, Harada H: Simultaneous detection of both single nucleotide variations and copy number alterations by next-generation sequencing in gorlin syndrome. PLOS One. 2015.11; 10 (11): e0140480. ( PubMed , DOI )

Naoto Fujiwara, Jun Inoue, Tatsuyuki Kawano, Kousuke Tanimoto, Ken-Ichi Kozaki, Johji Inazawa: miR-634 Activates the Mitochondrial Apoptosis Pathway and Enhances Chemotherapy-Induced Cytotoxicity. Cancer Res.. 2015.09; 75 (18): 3890-3901. ( PubMed , DOI )

Reiko Iwadate, Jun Inoue, Hitoshi Tsuda, Masashi Takano, Kenichi Furuya, Akira Hirasawa, Daisuke Aoki, Johji Inazawa: High Expression of p62 Protein Is Associated with Poor Prognosis and Aggressive Phenotypes in Endometrial Cancer. Am. J. Pathol.. 2015.09; 185 (9): 2523-2533. ( PubMed , DOI )

Yoh Dobashi, Hiroyoshi Tsubochi, Hirochika Matsubara, Jun Inoue, Johji Inazawa, Shunsuke Endo, Akishi Ooi: Diverse involvement of isoforms and gene aberrations of Akt in human lung carcinomas. Cancer Sci.. 2015.06; 106 (6): 772-781. ( PubMed , DOI )

Shin Hayashi, Mariko Yagi, Ichijiro Morisaki, Johji Inazawa: Identical deletion at 14q13.3 including PAX9 and NKX2-1 in siblings from mosaicism of unaffected parent. J. Hum. Genet.. 2015.04; 60 (4): 203-206. ( PubMed , DOI )

Hosoda F, Arai Y, Okada N, Shimizu H, Miyamoto M, Kitagawa N, Katai H, Taniguchi H, Yanagihara K, Imoto I, Inazawa J, Ohki M, Shibata T: Integrated genomic and functional analyses reveal glyoxalase I as a novel metabolic oncogene in human gastric cancer. Oncogene. 2015.02; 34 (9): 1196-1206. ( PubMed , DOI )

S Komatsu, D Ichikawa, S Hirajima, H Nagata, Y Nishimura, T Kawaguchi, M Miyamae, W Okajima, T Ohashi, H Konishi, A Shiozaki, H Fujiwara, K Okamoto, H Tsuda, I Imoto, J Inazawa, E Otsuji: Overexpression of SMYD2 contributes to malignant outcome in gastric cancer. Br. J. Cancer. 2015.01; 112 (2): 357-364. ( PubMed , DOI )

Matsumoto H, Zaha K, Nakamura Y, Hayashi S, Inazawa J, Nonoyama S: Chromosome 9q33q34 microdeletion with early infantile epileptic encephalopathy, severe dystonia, abnormal eye movements, and nephroureteral malformations. Pediatric neurology. 2014.07; 51 (1): 170-5. ( PubMed , DOI )

Matsumoto H, Zaha K, Nakamura Y, Hayashi S, Inazawa J, Nonoyama S: Chromosome 9q33q34 microdeletion with early infantile epileptic encephalopathy, severe　dystonia, abnormal eye movements, and nephroureteral malformations Pediatr　Neurol. 2014.07; 51 (1): 1196-1206.

Iwadate R, Inoue J, Tsuda H, Takano M, Furuya K, Hirasawa A, Aoki D, Inazawa J: High Expression of SQSTM1/p62 Protein Is Associated with Poor Prognosis in Epithelial Ovarian Cancer Acta Histochem Cytochem. 2014.06; 47 (6): 295-301.

Nishimura J, Yamamoto M, Hayashi S, Ohyashiki K, Ando K, Brodsky AL, Noji H, Kitamura K, Eto T, Takahashi T, Masuko M, Matsumoto T, Wano Y, Shichishima T, Shibayama H, Hase M, Li L, Johnson K, Lazarowski A, Tamburini P, Inazawa J, Kinoshita T, Kanakura Y: Genetic variants in C5 and poor response to eculizumab. N Engl J Med. 2014.02; 370 (7): 632-639. ( PubMed , DOI )

Takemura K, Kawachi H, Eishi Y, Kitagaki K, Negi M, Kobayashi M, Uchida K, Inoue J, Inazawa J, Kawano T, Board PG: γ-Glutamylcyclotransferase as a novel immunohistochemical biomarker for the malignancy of esophageal squamous tumors. Hum Pathol. 2014.02; 45 (2): 331-341. ( PubMed , DOI )

Dobashi Y, Sato E, Oda Y, Inazawa J, Ooi A: Significance of Akt activation and AKT gene increases in soft tissue tumors. Hum Pathol. 2014.01; 45 (1): 127-136. ( PubMed , DOI )

Yamamoto S, Inoue J, Kawano T, Kozaki K, Omura K, Inazawa J: The Impact of miRNA-Based Molecular Diagnostics and Treatment of NRF2-Stabilized Tumors. Mol Cancer Res. 2014.01; 12 (1): 58-68. ( PubMed , DOI )

Uno M, Saitoh Y, Mochida K, Tsuruyama E, Kiyono T, Imoto I, Inazawa J, Yuasa Y, Kubota T, Yamaoka S: NF-κB Inducing Kinase, a Central Signaling Component of the Non-Canonical Pathway of NF-κB, Contributes to Ovarian Cancer Progression. PLoS ONE. 2014; 9 (2): e88347. ( PubMed , DOI )

Iwadate R, Inoue J, Tsuda H, Takano M, Furuya K, Hirasawa A, Aoki D, Inazawa J: High Expression of SQSTM1/p62 Protein Is Associated with Poor Prognosis in Epithelial Ovarian Cancer. Acta histochemica et cytochemica. 2014; 47 (6): 295-301. ( PubMed , DOI )

Yamamoto Y, Konishi H, Ichikawa D, Arita T, Shoda K, Komatsu S, Shiozaki A, Ikoma H, Fujiwara H, Okamoto K, Ochiai T, Inoue J, Inazawa J, Otsuji E: Significance of GSTP1 for predicting the prognosis and chemotherapeutic efficacy in esophageal squamous cell carcinoma. Oncol Rep. 2013.10; 30 (4): 1687-1694. ( PubMed , DOI )

Endo H, Muramatsu T, Furuta M, Uzawa N, Pimkhaokham A, Amagasa T, Inazawa J, Kozaki K: Potential of tumor-suppressive miR-596 targeting LGALS3BP as a therapeutic agent in oral cancer. Carcinogenesis. 2013.03; 34 (3): 560-569. ( PubMed , DOI )

Miyawaki Y, Imoto I, Tokairin Y, Kawada K, Nakajima Y, Nishikage T, Nagai K, Kajiwara M, Inazawa J, Kawano T: Esophageal squamous cell carcinoma developed 11 years after allogeneic bone marrow transplantation for acute lymphatic leukemia. Jpn J Clin Oncol. 2013.01; 43 (1): 69-73. ( PubMed , DOI )

Low SK, Takahashi A, Ashikawa K, Inazawa J, Miki Y, Kubo M, Nakamura Y, Katagiri T: Genome-wide association study of breast cancer in the Japanese population. PLoS ONE. 2013; 8 (10): e76463. ( PubMed , DOI )

Furuta M, Kozaki K, Tanimoto K, Tanaka S, Arii S, Shimamura T, Niida A, Miyano S, Inazawa J: The tumor-suppressive miR-497-195 cluster targets multiple cell-cycle regulators in hepatocellular carcinoma. PLoS One. 2013; 8 (3): e60155. ( PubMed , DOI )

Harazono Y, Muramatsu T, Endo H, Uzawa N, Kawano T, Harada K, Inazawa J, Kozaki K: miR-655 Is an EMT-Suppressive MicroRNA Targeting ZEB1 and TGFBR2. PLoS One. 2013; 8 (5): e62757. ( PubMed , DOI )

Dobashi Y, Kimura M, Matsubara H, Endo S, Inazawa J, Ooi A: Molecular alterations in AKT and its protein activation in human lung carcinomas. Hum Pathol. 2012.12; 43 (12): 2229-2240. ( PubMed , DOI )

Takanashi J, Okamoto N, Yamamoto Y, Hayashi S, Arai H, Takahashi Y, Maruyama K, Mizuno S, Shimakawa S, Ono H, Oyanagi R, Kubo S, Barkovich AJ, Inazawa J: Clinical and radiological features of Japanese patients with a severe phenotype due to CASK mutations. Am J Med Genet A. 2012.12; 158A (12): 3112-3118. ( PubMed , DOI )

Gaffney CJ, Oka T, Mazack V, Hilman D, Gat U, Muramatsu T, Inazawa J, Golden A, Carey DJ, Farooq A, Tromp G, Sudol M: Identification, basic characterization and evolutionary analysis of differentially spliced mRNA isoforms of human YAP1 gene. Gene. 2012.11; 509 (2): 215-222. ( PubMed , DOI )

Ono H, Imoto I, Kozaki K, Tsuda H, Matsui T, Kurasawa Y, Muramatsu T, Sugihara K, Inazawa J: SIX1 promotes epithelial-mesenchymal transition in colorectal cancer through ZEB1 activation. Oncogene. 2012.11; 31 (47): 4923-4934. ( PubMed , DOI )

Bai H, Inoue J, Kawano T, Inazawa J: A transcriptional variant of the LC3A gene is involved in autophagy and frequently inactivated in human cancers. Oncogene. 2012.10; 31 (40): 4397-4408. ( PubMed , DOI )

Miyawaki Y, Kawachi H, Ooi A, Eishi Y, Kawano T, Inazawa J, Imoto I: Genomic copy-number alterations of MYC and FHIT genes are associated with survival in esophageal squamous-cell carcinoma. Cancer Sci. 2012.08; 103 (8): 1558-1566. ( PubMed , DOI )

Matsumura S, Imoto I, Kozaki K, Matsui T, Muramatsu T, Furuta M, Tanaka S, Sakamoto M, Arii S, Inazawa J: Integrative array-based approach identifies MZB1 as a frequently methylated putative tumor suppressor in hepatocellular carcinoma. Clin Cancer Res. 2012.07; 18 (13): 3541-3551. ( PubMed , DOI )

Honda S, Hayashi S, Nakane T, Imoto I, Kurosawa K, Mizuno S, Okamoto N, Kato M, Yoshihashi H, Kubota T, Nakagawa E, Goto Y, Inazawa J: The incidence of hypoplasia of the corpus callosum in patients with dup (X)(q28) involving MECP2 is associated with the location of distal breakpoints. Am J Med Genet A. 2012.06; 158A (6): 1292-1303. ( PubMed , DOI )

Yamamoto S, Tsuda H, Honda K, Takano M, Tamai S, Imoto I, Inazawa J, Yamada T, Matsubara O: ACTN4 gene amplification and actinin-4 protein overexpression drive tumour development and histological progression in a high-grade subset of ovarian clear-cell adenocarcinomas. Histopathology. 2012.06; 60 (7): 1073-1083. ( PubMed , DOI )

Kozaki K, Inazawa J: Tumor-suppressive microRNA silenced by tumor-specific DNA hypermethylation in cancer cells. Cancer science. 2012.05; 103 (5): 837-45. ( PubMed , DOI )

Ooi A, Inokuchi M, Harada S, Inazawa J, Tajiri R, Kitamura SS, Ikeda H, Kawashima H, Dobashi Y: Gene amplification of ESR1 in breast cancers--fact or fiction? A fluorescence in situ hybridization and multiplex ligation-dependent probe amplification study. J Pathol. 2012.05; 227 (1): 8-16. ( PubMed , DOI )

Akamatsu S, Takata R, Haiman CA, Takahashi A, Inoue T, Kubo M, Furihata M, Kamatani N, Inazawa J, Chen GK, Le Marchand L, Kolonel LN, Katoh T, Yamano Y, Yamakado M, Takahashi H, Yamada H, Egawa S, Fujioka T, Henderson BE, Habuchi T, Ogawa O, Nakamura Y, Nakagawa H: Common variants at 11q12, 10q26 and 3p11.2 are associated with prostate cancer susceptibility in Japanese. Nat Genet. 2012.04; 44 (4): 426-9, S1. ( PubMed , DOI )

Kurasawa Y, Kozaki K, Pimkhaokham A, Muramatsu T, Ono H, Ishihara T, Uzawa N, Imoto I, Amagasa T, Inazawa J: Stabilization of phenotypic plasticity through mesenchymal-specific DNA hypermethylation in cancer cells. Oncogene. 2012.04; 31 (15): 1963-1974. ( PubMed , DOI )

Okamoto N, Hayashi S, Masui A, Kosaki R, Oguri I, Hasegawa T, Imoto I, Makita Y, Hata A, Moriyama K, Inazawa J: Deletion at chromosome 10p11.23-p12.1 defines characteristic phenotypes with marked midface retrusion. J Hum Genet. 2012.03; 57 (3): 191-196. ( PubMed , DOI )

Maeda MH, Mitsui J, Soong BW, Takahashi Y, Ishiura H, Hayashi S, Shirota Y, Ichikawa Y, Matsumoto H, Arai M, Okamoto T, Miyama S, Shimizu J, Inazawa J, Goto J, Tsuji S: Increased gene dosage of myelin protein zero causes Charcot-Marie-Tooth disease. Ann Neurol. 2012.01; 71 (1): 84-92. ( PubMed , DOI )

Honda S, Satomura S, Hayashi S, Imoto I, Nakagawa E, Goto Y, Inazawa J: Concomitant microduplications of MECP2 and ATRX in male patients with severe mental retardation. J Hum Genet. 2012.01; 57 (1): 73-77. ( PubMed , DOI )

Hayashi S, Okamoto N, Chinen Y, Takanashi J, Makita Y, Hata A, Imoto I, Inazawa J: Novel intragenic duplications and mutations of CASK in patients with mental retardation and microcephaly with pontine and cerebellar hypoplasia (MICPCH). Hum Genet. 2012.01; 131 (1): 99-110. ( PubMed , DOI )

Ishihara T, Inoue J, Kozaki K, Imoto I, Inazawa J: HECT-type ubiquitin ligase ITCH targets lysosomal-associated protein multispanning transmembrane 5 (LAPTM5) and prevents LAPTM5-mediated cell death. J Biol Chem. 2011.12; 286 (51): 44086-44094. ( PubMed , DOI )

Tsuruta T, Kozaki K, Uesugi A, Furuta M, Hirasawa A, Imoto I, Susumu N, Aoki D, Inazawa J: miR-152 is a tumor suppressor microRNA that is silenced by DNA hypermethylation in endometrial cancer. Cancer Res. 2011.10; 71 (20): 6450-6462. ( PubMed , DOI )

Niihori T, Aoki Y, Okamoto N, Kurosawa K, Ohashi H, Mizuno S, Kawame H, Inazawa J, Ohura T, Arai H, Nabatame S, Kikuchi K, Kuroki Y, Miura M, Tanaka T, Ohtake A, Omori I, Ihara K, Mabe H, Watanabe K, Niijima S, Okano E, Numabe H, Matsubara Y: HRAS mutants identified in Costello syndrome patients can induce cellular senescence: possible implications for the pathogenesis of Costello syndrome. J Hum Genet. 2011.10; 56 (10): 707-715. ( PubMed , DOI )

Uesugi A, Kozaki K, Tsuruta T, Furuta M, Morita K, Imoto I, Omura K, Inazawa J: The tumor suppressive microRNA miR-218 targets the mTOR component Rictor and inhibits AKT phosphorylation in oral cancer. Cancer Res. 2011.09; 71 (17): 5765-5778. ( PubMed , DOI )

Matsui T, Miyamoto K, Kubo A, Kawasaki H, Ebihara T, Hata K, Tanahashi S, Ichinose S, Imoto I, Inazawa J, Kudoh J, Amagai M: SASPase regulates stratum corneum hydration through profilaggrin-to-filaggrin processing. EMBO Mol Med. 2011.06; 3 (6): 320-333. ( PubMed , DOI )

Nishiyama N, Arai E, Nagashio R, Fujimoto H, Hosoda F, Shibata T, Tsukamoto T, Yokoi S, Imoto I, Inazawa J, Kanai Y: Copy number alterations in urothelial carcinomas: their clinicopathological significance and correlation with DNA methylation alterations. Carcinogenesis. 2011.04; 32 (4): 462-469. ( PubMed , DOI )

Muramatsu T, Imoto I, Matsui T, Kozaki K, Haruki S, Sudol M, Shimada Y, Tsuda H, Kawano T, Inazawa J: YAP is a candidate oncogene for esophageal squamous cell carcinoma. Carcinogenesis. 2011.03; 32 (3): 389-398. ( PubMed , DOI )

Hayashi S, Imoto I, Aizu Y, Okamoto N, Mizuno S, Kurosawa K, Okamoto N, Honda S, Araki S, Mizutani S, Numabe H, Saitoh S, Kosho T, Fukushima Y, Mitsubuchi H, Endo F, Chinen Y, Kosaki R, Okuyama T, Ohki H, Yoshihashi H, Ono M, Takada F, Ono H, Yagi M, Matsumoto H, Makita Y, Hata A, Inazawa J: Clinical application of array-based comparative genomic hybridization by two-stage screening for 536 patients with mental retardation and multiple congenital anomalies. J Hum Genet. 2011.02; 56 (2): 110-124. ( PubMed , DOI )

Miyake K, Hirasawa T, Soutome M, Itoh M, Goto Y, Endoh K, Takahashi K, Kudo S, Nakagawa T, Yokoi S, Taira T, Inazawa J, Kubota T: The protocadherins, PCDHB1 and PCDH7, are regulated by MeCP2 in neuronal cells and brain tissues: implication for pathogenesis of Rett syndrome. BMC Neurosci. 2011; 12 81. ( PubMed , DOI )

Gotoh M, Arai E, Wakai-Ushijima S, Hiraoka N, Kosuge T, Hosoda F, Shibata T, Kondo T, Yokoi S, Imoto I, Inazawa J, Kanai Y: Diagnosis and prognostication of ductal adenocarcinomas of the pancreas based on genome-wide DNA methylation profiling by bacterial artificial chromosome array-based methylated CpG island amplification. J Biomed Biotechnol. 2011; 2011 780836. ( PubMed , DOI )

Arai E, Wakai-Ushijima S, Fujimoto H, Hosoda F, Shibata T, Kondo T, Yokoi S, Imoto I, Inazawa J, Hirohashi S, Kanai Y: Genome-wide DNA methylation profiles in renal tumors of various histological subtypes and non-tumorous renal tissues. Pathobiology. 2011; 78 (1): 1-9. ( PubMed , DOI )

Saitoh Y, Martinez Bruyn VJ, Uota S, Hasegawa A, Yamamoto N, Imoto I, Inazawa J, Yamaoka S: Overexpression of NF-kappaB inducing kinase underlies constitutive NF-kappaB activation in lung cancer cells. Lung Cancer. 2010.12; 70 (3): 263-270. ( PubMed , DOI )

Xu H, Miki K, Ishibashi S, Inoue J, Sun L, Endo S, Sekiya I, Muneta T, Inazawa J, Dezawa M, Mizusawa H: Transplantation of neuronal cells induced from human mesenchymal stem cells improves neurological functions after stroke without cell fusion. J Neurosci Res. 2010.12; 88 (16): 3598-3609. ( PubMed , DOI )

Tagi T, Matsui T, Kikuchi S, Hoshi S, Ochiai T, Kokuba Y, Kinoshita-Ida Y, Kisumi-Hayashi F, Morimoto K, Imai T, Imoto I, Inazawa J, Otsuji E: Dermokine as a novel biomarker for early-stage colorectal cancer. J Gastroenterol. 2010.12; 45 (12): 1201-1211. ( PubMed , DOI )

Miki D, Kubo M, Takahashi A, Yoon KA, Kim J, Lee GK, Zo JI, Lee JS, Hosono N, Morizono T, Tsunoda T, Kamatani N, Chayama K, Takahashi T, Inazawa J, Nakamura Y, Daigo Y: Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations. Nat Genet. 2010.10; 42 (10): 893-896. ( PubMed , DOI )

Takanashi J, Arai H, Nabatame S, Hirai S, Hayashi S, Inazawa J, Okamoto N, Barkovich AJ: Neuroradiologic features of CASK mutations. AJNR Am J Neuroradiol. 2010.10; 31 (9): 1619-1622. ( PubMed , DOI )

Honda S, Hayashi S, Imoto I, Toyama J, Okazawa H, Nakagawa E, Goto Y, Inazawa J: Copy-number variations on the X chromosome in Japanese patients with mental retardation detected by array-based comparative genomic hybridization analysis. J Hum Genet. 2010.09; 55 (9): 590-599. ( PubMed , DOI )

Takata R, Akamatsu S, Kubo M, Takahashi A, Hosono N, Kawaguchi T, Tsunoda T, Inazawa J, Kamatani N, Ogawa O, Fujioka T, Nakamura Y, Nakagawa H: Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population. Nat Genet. 2010.09; 42 (9): 751-754. ( PubMed , DOI )

Prapinjumrune C, Morita K, Kuribayashi Y, Hanabata Y, Shi Q, Nakajima Y, Inazawa J, Omura K: DNA amplification and expression of FADD in oral squamous cell carcinoma. J Oral Pathol Med. 2010.08; 39 (7): 525-532. ( PubMed , DOI )

Shibata T, Kokubu A, Miyamoto M, Hosoda F, Gotoh M, Tsuta K, Asamura H, Matsuno Y, Kondo T, Imoto I, Inazawa J, Hirohashi S: DEK oncoprotein regulates transcriptional modifiers and sustains tumor initiation activity in high-grade neuroendocrine carcinoma of the lung. Oncogene. 2010.08; 29 (33): 4671-4681. ( PubMed , DOI )

Haruki S, Imoto I, Kozaki K, Matsui T, Kawachi H, Komatsu S, Muramatsu T, Shimada Y, Kawano T, Inazawa J: Frequent silencing of protocadherin 17, a candidate tumour suppressor for esophageal squamous cell carcinoma. Carcinogenesis. 2010.06; 31 (6): 1027-1036. ( PubMed , DOI )

Furuta M, Kozaki KI, Tanaka S, Arii S, Imoto I, Inazawa J: miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma. Carcinogenesis. 2010.05; 31 (5): 766-776. ( PubMed , DOI )

Honda S, Orii KO, Kobayashi J, Hayashi S, Imamura A, Imoto I, Nakagawa E, Goto Y, Inazawa J: Novel deletion at Xq24 including the UBE2A gene in a patient with X-linked mental retardation. J Hum Genet. 2010.04; 55 (4): 244-247. ( PubMed , DOI )

Tanaka S, Mogushi K, Yasen M, Noguchi N, Kudo A, Nakamura N, Ito K, Miki Y, Inazawa J, Tanaka H, Arii S: Gene-expression phenotypes for vascular invasiveness of hepatocellular carcinomas. Surgery. 2010.03; 147 (3): 405-414. ( PubMed , DOI )

Nishiyama N, Arai E, Chihara Y, Fujimoto H, Hosoda F, Shibata T, Kondo T, Tsukamoto T, Yokoi S, Imoto I, Inazawa J, Hirohashi S, Kanai Y: Genome-wide DNA methylation profiles in urothelial carcinomas and urothelia at the precancerous stage. Cancer Sci. 2010.01; 101 (1): 231-240. ( PubMed , DOI )

Arai E, Ushijima S, Gotoh M, Ojima H, Kosuge T, Hosoda F, Shibata T, Kondo T, Yokoi S, Imoto I, Inazawa J, Hirohashi S, Kanai Y: Genome-wide DNA methylation profiles in liver tissue at the precancerous stage and in hepatocellular carcinoma. Int J Cancer. 2009.12; 125 (12): 2854-2862. ( PubMed , DOI )

Kubo T, Kuroda Y, Shimizu H, Kokubu A, Okada N, Hosoda F, Arai Y, Nakamura Y, Taniguchi H, Yanagihara K, Imoto I, Inazawa J, Hirohashi S, Shibata T: Resequencing and copy number analysis of the human tyrosine kinase gene family in poorly differentiated gastric cancer. Carcinogenesis. 2009.11; 30 (11): 1857-1864. ( PubMed , DOI )

Begum A, Imoto I, Kozaki K, Tsuda H, Suzuki E, Amagasa T, Inazawa J: Identification of PAK4 as a putative target gene for amplification within 19q13.12-q13.2 in oral squamous-cell carcinoma. Cancer Sci. 2009.10; 100 (10): 1908-1916. ( PubMed , DOI )

Nakamura Y, Migita T, Hosoda F, Okada N, Gotoh M, Arai Y, Fukushima M, Ohki M, Miyata S, Takeuchi K, Imoto I, Katai H, Yamaguchi T, Inazawa J, Hirohashi S, Ishikawa Y, Shibata T: Kruppel-like factor 12 plays a significant role in poorly differentiated gastric cancer progression. Int J Cancer. 2009.10; 125 (8): 1859-1867. ( PubMed , DOI )

Komatsu S, Imoto I, Tsuda H, Kozaki KI, Muramatsu T, Shimada Y, Aiko S, Yoshizumi Y, Ichikawa D, Otsuji E, Inazawa J: Overexpression of SMYD2 relates to tumor cell proliferation and malignant outcome of esophageal squamous cell carcinoma. Carcinogenesis. 2009.07; 30 (7): 1139-1146. ( PubMed , DOI )

Fujita K, Sanada M, Harada H, Mori H, Niikura H, Omine M, Inazawa J, Imoto I: Molecular cloning of t(2;7)(p24.3;p14.2), a novel chromosomal translocation in myelodysplastic syndrome-derived acute myeloid leukemia. J Hum Genet. 2009.06; 54 (6): 355-359. ( PubMed , DOI )

Iriyama T, Takeda K, Nakamura H, Morimoto Y, Kuroiwa T, Mizukami J, Umeda T, Noguchi T, Naguro I, Nishitoh H, Saegusa K, Tobiume K, Homma T, Shimada Y, Tsuda H, Aiko S, Imoto I, Inazawa J, Chida K, Kamei Y, Kozuma S, Taketani Y, Matsuzawa A, Ichijo H: ASK1 and ASK2 differentially regulate the counteracting roles of apoptosis and inflammation in tumorigenesis. EMBO J. 2009.04; 28 (7): 843-853. ( PubMed , DOI )

Yamamoto S, Tsuda H, Honda K, Onozato K, Takano M, Tamai S, Imoto I, Inazawa J, Yamada T, Matsubara O: Actinin-4 gene amplification in ovarian cancer: a candidate oncogene associated with poor patient prognosis and tumor chemoresistance. Mod Pathol. 2009.04; 22 (4): 499-507. ( PubMed , DOI )

Tanaka S, Mogushi K, Yasen M, Noguchi N, Kudo A, Kurokawa T, Nakamura N, Inazawa J, Tanaka H, Arii S: Surgical contribution to recurrence-free survival in patients with macrovascular-invasion-negative hepatocellular carcinoma. J Am Coll Surg. 2009.03; 208 (3): 368-374. ( PubMed , DOI )

Kawase T, Ohki R, Shibata T, Tsutsumi S, Kamimura N, Inazawa J, Ohta T, Ichikawa H, Aburatani H, Tashiro F, Taya Y: PH domain-only protein PHLDA3 is a p53-regulated repressor of Akt. Cell. 2009.02; 136 (3): 535-550. ( PubMed , DOI )

Arai E, Ushijima S, Fujimoto H, Hosoda F, Shibata T, Kondo T, Yokoi S, Imoto I, Inazawa J, Hirohashi S, Kanai Y: Genome-wide DNA methylation profiles in both precancerous conditions and clear cell renal cell carcinomas are correlated with malignant potential and patient outcome. Carcinogenesis. 2009.02; 30 (2): 214-221. ( PubMed , DOI )

Takahata M, Inoue Y, Tsuda H, Imoto I, Koinuma D, Hayashi M, Ichikura T, Yamori T, Nagasaki K, Yoshida M, Matsuoka M, Morishita K, Yuki K, Hanyu A, Miyazawa K, Inazawa J, Miyazono K, Imamura T: SKI and MEL1 cooperate to inhibit transforming growth factor-beta signal in gastric cancer cells. J Biol Chem. 2009.01; 284 (5): 3334-3344. ( PubMed , DOI )

Inoue J, Misawa A, Tanaka Y, Ichinose S, Sugino Y, Hosoi H, Sugimoto T, Imoto I, Inazawa J: Lysosomal-associated protein multispanning transmembrane 5 gene (LAPTM5) is associated with spontaneous regression of neuroblastomas. PLoS One. 2009; 4 (9): e7099. ( PubMed , DOI )

Hayashi S, Okamoto N, Makita Y, Hata A, Imoto I, Inazawa J: Heterozygous deletion at 14q22.1-q22.3 including the BMP4 gene in a patient with psychomotor retardation, congenital corneal opacity and feet polysyndactyly. Am J Med Genet A. 2008.11; 146A (22): 2905-2910. ( PubMed , DOI )

Qi S, Mogi S, Tsuda H, Tanaka Y, Kozaki K, Imoto I, Inazawa J, Hasegawa S, Omura K: Expression of cIAP-1 correlates with nodal metastasis in squamous cell carcinoma of the tongue. Int J Oral Maxillofac Surg. 2008.11; 37 (11): 1047-1053. ( PubMed , DOI )

Ishihara T, Tsuda H, Hotta A, Kozaki K, Yoshida A, Noh JY, Ito K, Imoto I, Inazawa J: ITCH is a putative target for a novel 20q11.22 amplification detected in anaplastic thyroid carcinoma cells by array-based comparative genomic hybridization. Cancer Sci. 2008.10; 99 (10): 1940-1949. ( PubMed , DOI )

Kikuchi S, Honda K, Tsuda H, Hiraoka N, Imoto I, Kosuge T, Umaki T, Onozato K, Shitashige M, Yamaguchi U, Ono M, Tsuchida A, Aoki T, Inazawa J, Hirohashi S, Yamada T: Expression and gene amplification of actinin-4 in invasive ductal carcinoma of the pancreas. Clin Cancer Res. 2008.09; 14 (17): 5348-5356. ( PubMed , DOI )

Nakajima T, Yasui K, Zen K, Inagaki Y, Fujii H, Minami M, Tanaka S, Taniwaki M, Itoh Y, Arii S, Inazawa J, Okanoue T: Activation of B-Myb by E2F1 in hepatocellular carcinoma. Hepatol Res. 2008.09; 38 (9): 886-895. ( PubMed , DOI )

Arai E, Ushijima S, Tsuda H, Fujimoto H, Hosoda F, Shibata T, Kondo T, Imoto I, Inazawa J, Hirohashi S, Kanai Y: Genetic clustering of clear cell renal cell carcinoma based on array-comparative genomic hybridization: its association with DNA methylation alteration and patient outcome. Clin Cancer Res. 2008.09; 14 (17): 5531-5539. ( PubMed , DOI )

Hayashi S, Mizuno S, Migita O, Okuyama T, Makita Y, Hata A, Imoto I, Inazawa J: The CASK gene harbored in a deletion detected by array-CGH as a potential candidate for a gene causative of X-linked dominant mental retardation. Am J Med Genet A. 2008.08; 146A (16): 2145-2151. ( PubMed , DOI )

Katsuki Y, Nakada S, Yokoyama T, Imoto I, Inazawa J, Nagasawa M, Mizutani S: Caffeine yields aneuploidy through asymmetrical cell division caused by misalignment of chromosomes. Cancer Sci. 2008.08; 99 (8): 1539-1545. ( PubMed , DOI )

Nakamura E, Kozaki K, Tsuda H, Suzuki E, Pimkhaokham A, Yamamoto G, Irie T, Tachikawa T, Amagasa T, Inazawa J, Imoto I: Frequent silencing of a putative tumor suppressor gene melatonin receptor 1 A (MTNR1A) in oral squamous-cell carcinoma. Cancer Sci. 2008.07; 99 (7): 1390-1400. ( PubMed , DOI )

Kikuchi R, Tsuda H, Kozaki K, Kanai Y, Kasamatsu T, Sengoku K, Hirohashi S, Inazawa J, Imoto I: Frequent inactivation of a putative tumor suppressor, angiopoietin-like protein 2, in ovarian cancer. Cancer Res. 2008.07; 68 (13): 5067-5075. ( PubMed , DOI )

Tanaka S, Arii S, Yasen M, Mogushi K, Su NT, Zhao C, Imoto I, Eishi Y, Inazawa J, Miki Y, Tanaka H: Aurora kinase B is a predictive factor for the aggressive recurrence of hepatocellular carcinoma after curative hepatectomy. Br J Surg. 2008.05; 95 (5): 611-619. ( PubMed , DOI )

Saitoh Y, Yamamoto N, Dewan MZ, Sugimoto H, Martinez Bruyn VJ, Iwasaki Y, Matsubara K, Qi X, Saitoh T, Imoto I, Inazawa J, Utsunomiya A, Watanabe T, Masuda T, Yamamoto N, Yamaoka S: Overexpressed NF-kappaB-inducing kinase contributes to the tumorigenesis of adult T-cell leukemia and Hodgkin Reed-Sternberg cells. Blood. 2008.05; 111 (10): 5118-5129. ( PubMed , DOI )

Suzuki A, Shibata T, Shimada Y, Murakami Y, Horii A, Shiratori K, Hirohashi S, Inazawa J, Imoto I: Identification of SMURF1 as a possible target for 7q21.3-22.1 amplification detected in a pancreatic cancer cell line by in-house array-based comparative genomic hybridization. Cancer Sci. 2008.05; 99 (5): 986-994. ( PubMed , DOI )

Kozaki K, Imoto I, Mogi S, Omura K, Inazawa J: Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer. Cancer Res. 2008.04; 68 (7): 2094-2105. ( PubMed , DOI )

Zhao C, Inoue J, Imoto I, Otsuki T, Iida S, Ueda R, Inazawa J: POU2AF1, an amplification target at 11q23, promotes growth of multiple myeloma cells by directly regulating expression of a B-cell maturation factor, TNFRSF17. Oncogene. 2008.01; 27 (1): 63-75. ( PubMed , DOI )

Okamoto N, Kubota T, Nakamura Y, Murakami R, Nishikubo T, Tanaka I, Takahashi Y, Hayashi S, Imoto I, Inazawa J, Hosokai N, Kohsaka S, Uchino S: 22q13 Microduplication in two patients with common clinical manifestations: a recognizable syndrome? Am J Med Genet A. 2007.12; 143A (23): 2804-2809. ( PubMed , DOI )

Suzuki E, Imoto I, Pimkhaokham A, Nakagawa T, Kamata N, Kozaki KI, Amagasa T, Inazawa J: PRTFDC1, a possible tumor-suppressor gene, is frequently silenced in oral squamous-cell carcinomas by aberrant promoter hypermethylation. Oncogene. 2007.12; 26 (57): 7921-7932. ( PubMed , DOI )

Yamamoto S, Tsuda H, Honda K, Kita T, Takano M, Tamai S, Inazawa J, Yamada T, Matsubara O: Actinin-4 expression in ovarian cancer: a novel prognostic indicator independent of clinical stage and histological type. Mod Pathol. 2007.12; 20 (12): 1278-1285. ( PubMed , DOI )

Katoh H, Ojima H, Kokubu A, Saito S, Kondo T, Kosuge T, Hosoda F, Imoto I, Inazawa J, Hirohashi S, Shibata T: Genetically distinct and clinically relevant classification of hepatocellular carcinoma: putative therapeutic targets. Gastroenterology. 2007.11; 133 (5): 1475-1486. ( PubMed , DOI )

Sugino Y, Misawa A, Inoue J, Kitagawa M, Hosoi H, Sugimoto T, Imoto I, Inazawa J: Epigenetic silencing of prostaglandin E receptor 2 (PTGER2) is associated with progression of neuroblastomas. Oncogene. 2007.11; 26 (53): 7401-7413. ( PubMed , DOI )

Arai A, Yan W, Wakabayashi S, Hayashi S, Inazawa J, Miura O: Successful imatinib treatment of cardiac involvement of FIP1L1-PDGFRA-positive chronic eosinophilic leukemia followed by severe hepatotoxicity. Int J Hematol. 2007.10; 86 (3): 233-237. ( PubMed , DOI )

Morita D, Tsuda H, Ichikura T, Kimura M, Aida S, Kosuda S, Inazawa J, Mochizuki H, Matsubara O: Analysis of sentinel node involvement in gastric cancer. Clin Gastroenterol Hepatol. 2007.09; 5 (9): 1046-1052. ( PubMed , DOI )

Tanaka K, Imoto I, Inoue J, Kozaki K, Tsuda H, Shimada Y, Aiko S, Yoshizumi Y, Iwai T, Kawano T, Inazawa J: Frequent methylation-associated silencing of a candidate tumor-suppressor, CRABP1, in esophageal squamous-cell carcinoma. Oncogene. 2007.09; 26 (44): 6456-6468. ( PubMed , DOI )

Kikuchi R, Tsuda H, Kanai Y, Kasamatsu T, Sengoku K, Hirohashi S, Inazawa J, Imoto I: Promoter hypermethylation contributes to frequent inactivation of a putative conditional tumor suppressor gene connective tissue growth factor in ovarian cancer. Cancer Res. 2007.08; 67 (15): 7095-7105. ( PubMed , DOI )

Yamamoto S, Tsuda H, Kita T, Maekawa K, Fujii K, Kudoh K, Furuya K, Tamai S, Inazawa J, Matsubara O: Clinicopathological significance of WT1 expression in ovarian cancer: a possible accelerator of tumor progression in serous adenocarcinoma. Virchows Arch. 2007.07; 451 (1): 27-35. ( PubMed , DOI )

Kawanishi H, Takahashi T, Ito M, Matsui Y, Watanabe J, Ito N, Kamoto T, Kadowaki T, Tsujimoto G, Imoto I, Inazawa J, Nishiyama H, Ogawa O: Genetic analysis of multifocal superficial urothelial cancers by array-based comparative genomic hybridisation. Br J Cancer. 2007.07; 97 (2): 260-266. ( PubMed , DOI )

Shinoda Y, Kozaki K, Imoto I, Obara W, Tsuda H, Mizutani Y, Shuin T, Fujioka T, Miki T, Inazawa J: Association of KLK5 overexpression with invasiveness of urinary bladder carcinoma cells. Cancer Sci. 2007.07; 98 (7): 1078-1086. ( PubMed , DOI )

Kawasaki T, Yokoi S, Tsuda H, Izumi H, Kozaki K, Aida S, Ozeki Y, Yoshizawa Y, Imoto I, Inazawa J: BCL2L2 is a probable target for novel 14q11.2 amplification detected in a non-small cell lung cancer cell line. Cancer Sci. 2007.07; 98 (7): 1070-1077. ( PubMed , DOI )

Chiyonobu T, Hayashi S, Kobayashi K, Morimoto M, Miyanomae Y, Nishimura A, Nishimoto A, Ito C, Imoto I, Sugimoto T, Jia Z, Inazawa J, Toda T: Partial tandem duplication of GRIA3 in a male with mental retardation. Am J Med Genet A. 2007.07; 143A (13): 1448-1455. ( PubMed , DOI )

Tokutomi T, Hayashi S, Imai K, Chida A, Ishiwata T, Asano Y, Inazawa J, Nonoyama S: dup(8p)/del(8q) recombinant chromosome in a girl with hepatic focal nodular hyperplasia. Am J Med Genet A. 2007.06; 143A (12): 1334-1337. ( PubMed , DOI )

Mitsui F, Dobashi Y, Imoto I, Inazawa J, Kono K, Fujii H, Ooi A: Non-incidental coamplification of Myc and ERBB2, and Myc and EGFR, in gastric adenocarcinomas. Mod Pathol. 2007.06; 20 (6): 622-631. ( PubMed , DOI )

Hayashi S, Ono M, Makita Y, Imoto I, Mizutani S, Inazawa J: Fortuitous detection of a submicroscopic deletion at 1q25 in a girl with Cornelia-de Lange syndrome carrying t(5;13)(p13.1;q12.1) by array-based comparative genomic hybridization. Am J Med Genet A. 2007.06; 143A (11): 1191-1197. ( PubMed , DOI )

Honda S, Hayashi S, Kato M, Niida Y, Hayasaka K, Okuyama T, Imoto I, Mizutani S, Inazawa J: Clinical and molecular cytogenetic characterization of two patients with non-mutational aberrations of the FMR2 gene. Am J Med Genet A. 2007.04; 143 (7): 687-693. ( PubMed , DOI )

Maekawa T, Shinagawa T, Sano Y, Sakuma T, Nomura S, Nagasaki K, Miki Y, Saito-Ohara F, Inazawa J, Kohno T, Yokota J, Ishii S: Reduced levels of ATF-2 predispose mice to mammary tumors. Mol Cell Biol. 2007.03; 27 (5): 1730-1744. ( PubMed , DOI )

Loukopoulos P, Shibata T, Katoh H, Kokubu A, Sakamoto M, Yamazaki K, Kosuge T, Kanai Y, Hosoda F, Imoto I, Ohki M, Inazawa J, Hirohashi S: Genome-wide array-based comparative genomic hybridization analysis of pancreatic adenocarcinoma: identification of genetic indicators that predict patient outcome. Cancer Sci. 2007.03; 98 (3): 392-400. ( PubMed , DOI )

Saigusa K, Imoto I, Tanikawa C, Aoyagi M, Ohno K, Nakamura Y, Inazawa J: RGC32, a novel p53-inducible gene, is located on centrosomes during mitosis and results in G2/M arrest. Oncogene. 2007.02; 26 (8): 1110-1121. ( PubMed , DOI )

Tanaka E, Hashimoto Y, Ito T, Kondo K, Higashiyama M, Tsunoda S, Ortiz C, Sakai Y, Inazawa J, Shimada Y: The suppression of aurora-A/STK15/BTAK expression enhances chemosensitivity to docetaxel in human esophageal squamous cell carcinoma. Clin Cancer Res. 2007.02; 13 (4): 1331-1340. ( PubMed , DOI )

Yu W, Imoto I, Inoue J, Onda M, Emi M, Inazawa J: A novel amplification target, DUSP26, promotes anaplastic thyroid cancer cell growth by inhibiting p38 MAPK activity. Oncogene. 2007.02; 26 (8): 1178-1187. ( PubMed , DOI )

Hayashi S, Honda S, Minaguchi M, Makita Y, Okamoto N, Kosaki R, Okuyama T, Imoto I, Mizutani S, Inazawa J: Construction of a high-density and high-resolution human chromosome X array for comparative genomic hybridization analysis. J Hum Genet. 2007; 52 (5): 397-405. ( PubMed , DOI )

Amino T, Ishikawa K, Toru S, Ishiguro T, Sato N, Tsunemi T, Murata M, Kobayashi K, Inazawa J, Toda T, Mizusawa H: Redefining the disease locus of 16q22.1-linked autosomal dominant cerebellar ataxia. J Hum Genet. 2007; 52 (8): 643-649. ( PubMed , DOI )

Udaka T, Imoto I, Aizu Y, Torii C, Izumi K, Kosaki R, Takahashi T, Hayashi S, Inazawa J, Kosaki K: Multiplex PCR/liquid chromatography assay for screening of subtelomeric rearrangements. (2007FA) Genet Test. 2007; 11 (3): 241-248. ( PubMed , DOI )

Kozaki K, Imoto I, Pimkhaokham A, Hasegawa S, Tsuda H, Omura K, Inazawa J: PIK3CA mutation is an oncogenic aberration at advanced stages of oral squamous cell carcinoma. Cancer Sci. 2006.12; 97 (12): 1351-1358. ( PubMed , DOI )

Nakagawa T, Pimkhaokham A, Suzuki E, Omura K, Inazawa J, Imoto I: Genetic or epigenetic silencing of low density lipoprotein receptor-related protein 1B expression in oral squamous cell carcinoma. Cancer Sci. 2006.10; 97 (10): 1070-1074. ( PubMed , DOI )

Takada H, Imoto I, Tsuda H, Nakanishi Y, Sakakura C, Mitsufuji S, Hirohashi S, Inazawa J: Genomic loss and epigenetic silencing of very-low-density lipoprotein receptor involved in gastric carcinogenesis. Oncogene. 2006.10; 25 (49): 6554-6562. ( PubMed , DOI )

Suzuki T, Delgado-Escueta AV, Alonso ME, Morita R, Okamura N, Sugimoto Y, Bai D, Medina MT, Bailey JN, Rasmussen A, Ramos-Peek J, Cordova S, Rubio-Donnadieu F, Ochoa A, Jara-Prado A, Inazawa J, Yamakawa K: Mutation analyses of genes on 6p12-p11 in patients with juvenile myoclonic epilepsy. Neurosci Lett. 2006.09; 405 (1-2): 126-131. ( PubMed , DOI )

Imoto I, Izumi H, Yokoi S, Hosoda H, Shibata T, Hosoda F, Ohki M, Hirohashi S, Inazawa J: Frequent silencing of the candidate tumor suppressor PCDH20 by epigenetic mechanism in non-small-cell lung cancers. Cancer Res. 2006.05; 66 (9): 4617-4626. ( PubMed , DOI )

Kumada K, Yao R, Kawaguchi T, Karasawa M, Hoshikawa Y, Ichikawa K, Sugitani Y, Imoto I, Inazawa J, Sugawara M, Yanagida M, Noda T: The selective continued linkage of centromeres from mitosis to interphase in the absence of mammalian separase. J Cell Biol. 2006.03; 172 (6): 835-846. ( PubMed , DOI )

Nishioka K, Hayashi S, Farrer MJ, Singleton AB, Yoshino H, Imai H, Kitami T, Sato K, Kuroda R, Tomiyama H, Mizoguchi K, Murata M, Toda T, Imoto I, Inazawa J, Mizuno Y, Hattori N: Clinical heterogeneity of alpha-synuclein gene duplication in Parkinson's disease. Ann Neurol. 2006.02; 59 (2): 298-309. ( PubMed , DOI )

Nakada S, Katsuki Y, Imoto I, Yokoyama T, Nagasawa M, Inazawa J, Mizutani S: Early G2/M checkpoint failure as a molecular mechanism underlying etoposide-induced chromosomal aberrations. J Clin Invest. 2006.01; 116 (1): 80-89. ( PubMed , DOI )

Takada H, Imoto I, Tsuda H, Nakanishi Y, Ichikura T, Mochizuki H, Mitsufuji S, Hosoda F, Hirohashi S, Ohki M, Inazawa J: ADAM23, a possible tumor suppressor gene, is frequently silenced in gastric cancers by homozygous deletion or aberrant promoter hypermethylation. Oncogene. 2005.12; 24 (54): 8051-8060. ( PubMed , DOI )

Hayashi S, Kurosawa K, Imoto I, Mizutani S, Inazawa J: Detection of cryptic chromosome aberrations in a patient with a balanced t(1;9)(p34.2;p24) by array-based comparative genomic hybridization. Am J Med Genet A. 2005.11; 139 (1): 32-36. ( PubMed , DOI )

Katoh H, Shibata T, Kokubu A, Ojima H, Loukopoulos P, Kanai Y, Kosuge T, Fukayama M, Kondo T, Sakamoto M, Hosoda F, Ohki M, Imoto I, Inazawa J, Hirohashi S: Genetic profile of hepatocellular carcinoma revealed by array-based comparative genomic hybridization: identification of genetic indicators to predict patient outcome. J Hepatol. 2005.11; 43 (5): 863-874. ( PubMed , DOI )

Misawa A, Inoue J, Sugino Y, Hosoi H, Sugimoto T, Hosoda F, Ohki M, Imoto I, Inazawa J: Methylation-associated silencing of the nuclear receptor 1I2 gene in advanced-type neuroblastomas, identified by bacterial artificial chromosome array-based methylated CpG island amplification. Cancer Res. 2005.11; 65 (22): 10233-10242. ( PubMed , DOI )

Saigusa K, Hashimoto N, Tsuda H, Yokoi S, Maruno M, Yoshimine T, Aoyagi M, Ohno K, Imoto I, Inazawa J: Overexpressed Skp2 within 5p amplification detected by array-based comparative genomic hybridization is associated with poor prognosis of glioblastomas. Cancer Sci. 2005.10; 96 (10): 676-683. ( PubMed , DOI )

Peng WX, Shibata T, Katoh H, Kokubu A, Matsuno Y, Asamura H, Tsuchiya R, Kanai Y, Hosoda F, Sakiyama T, Ohki M, Imoto I, Inazawa J, Hirohashi S: Array-based comparative genomic hybridization analysis of high-grade neuroendocrine tumors of the lung. Cancer Sci. 2005.10; 96 (10): 661-667. ( PubMed , DOI )

Tanami H, Tsuda H, Okabe S, Iwai T, Sugihara K, Imoto I, Inazawa J: Involvement of cyclin D3 in liver metastasis of colorectal cancer, revealed by genome-wide copy-number analysis. Lab Invest. 2005.09; 85 (9): 1118-1129. ( PubMed , DOI )

Shibata T, Uryu S, Kokubu A, Hosoda F, Ohki M, Sakiyama T, Matsuno Y, Tsuchiya R, Kanai Y, Kondo T, Imoto I, Inazawa J, Hirohashi S: Genetic classification of lung adenocarcinoma based on array-based comparative genomic hybridization analysis: its association with clinicopathologic features. Clin Cancer Res. 2005.09; 11 (17): 6177-6185. ( PubMed , DOI )

Ban S, Michikawa Y, Ishikawa K, Sagara M, Watanabe K, Shimada Y, Inazawa J, Imai T: Radiation sensitivities of 31 human oesophageal squamous cell carcinoma cell lines. Int J Exp Pathol. 2005.08; 86 (4): 231-240. ( PubMed , DOI )

Matsumoto T, Okamoto R, Yajima T, Mori T, Okamoto S, Ikeda Y, Mukai M, Yamazaki M, Oshima S, Tsuchiya K, Nakamura T, Kanai T, Okano H, Inazawa J, Hibi T, Watanabe M: Increase of bone marrow-derived secretory lineage epithelial cells during regeneration in the human intestine. Gastroenterology. 2005.06; 128 (7): 1851-1867. ( PubMed , DOI )

Tanimoto T, Tsuda H, Imazeki N, Ohno Y, Imoto I, Inazawa J, Matsubara O: Nuclear expression of cIAP-1, an apoptosis inhibiting protein, predicts lymph node metastasis and poor patient prognosis in head and neck squamous cell carcinomas. Cancer Lett. 2005.06; 224 (1): 141-151. ( PubMed , DOI )

Kuroda H, Moritake H, Sawada K, Kuwahara Y, Imoto I, Inazawa J, Sugimoto T: Establishment of a cell line from a malignant rhabdoid tumor of the liver lacking the function of two tumor suppressor genes, hSNF5/INI1 and p16. Cancer Genet Cytogenet. 2005.04; 158 (2): 172-179. ( PubMed , DOI )

Izumi H, Inoue J, Yokoi S, Hosoda H, Shibata T, Sunamori M, Hirohashi S, Inazawa J, Imoto I: Frequent silencing of DBC1 is by genetic or epigenetic mechanisms in non-small cell lung cancers. Hum Mol Genet. 2005.04; 14 (8): 997-1007. ( PubMed , DOI )

Ban S, Ishikawa K, Kawai S, Koyama-Saegusa K, Ishikawa A, Shimada Y, Inazawa J, Imai T: Potential in a single cancer cell to produce heterogeneous morphology, radiosensitivity and gene expression. J Radiat Res. 2005.03; 46 (1): 43-50. ( PubMed )

Tanaka E, Hashimoto Y, Ito T, Okumura T, Kan T, Watanabe G, Imamura M, Inazawa J, Shimada Y: The clinical significance of Aurora-A/STK15/BTAK expression in human esophageal squamous cell carcinoma. Clin Cancer Res. 2005.03; 11 (5): 1827-1834. ( PubMed , DOI )

Takada H, Imoto I, Tsuda H, Sonoda I, Ichikura T, Mochizuki H, Okanoue T, Inazawa J: Screening of DNA copy-number aberrations in gastric cancer cell lines by array-based comparative genomic hybridization. Cancer Sci. 2005.02; 96 (2): 100-110. ( PubMed , DOI )

Shinto E, Tsuda H, Ueno H, Hashiguchi Y, Hase K, Tamai S, Mochizuki H, Inazawa J, Matsubara O: Prognostic implication of laminin-5 gamma 2 chain expression in the invasive front of colorectal cancers, disclosed by area-specific four-point tissue microarrays. Lab Invest. 2005.02; 85 (2): 257-266. ( PubMed , DOI )

Susumu N, Aoki D, Noda T, Nagashima Y, Hirao T, Tamada Y, Banno K, Suzuki A, Suzuki N, Tsuda H, Inazawa J, Nozawa S: Diagnostic clinical application of two-color fluorescence in situ hybridization that detects chromosome 1 and 17 alterations to direct touch smear and liquid-based thin-layer cytologic preparations of endometrial cancers. Int J Gynecol Cancer. 2005.01; 15 (1): 70-80. ( PubMed , DOI )

Tsuda H, Morita D, Kimura M, Shinto E, Ohtsuka Y, Matsubara O, Inazawa J, Tamaki K, Mochizuki H, Tamai S, Hiraide H: Correlation of KIT and EGFR overexpression with invasive ductal breast carcinoma of the solid-tubular subtype, nuclear grade 3, and mesenchymal or myoepithelial differentiation. Cancer Sci. 2005.01; 96 (1): 48-53. ( PubMed , DOI )

Sanada T, Yokoi S, Arii S, Yasui K, Imoto I, Inazawa J: Skp2 overexpression is a p27Kip1-independent predictor of poor prognosis in patients with biliary tract cancers. Cancer Sci. 2004.12; 95 (12): 969-976. ( PubMed , DOI )

Tanami H, Imoto I, Hirasawa A, Yuki Y, Sonoda I, Inoue J, Yasui K, Misawa-Furihata A, Kawakami Y, Inazawa J: Involvement of overexpressed wild-type BRAF in the growth of malignant melanoma cell lines. Oncogene. 2004.11; 23 (54): 8796-8804. ( PubMed , DOI )

Suzuki T, Delgado-Escueta AV, Aguan K, Alonso ME, Shi J, Hara Y, Nishida M, Numata T, Medina MT, Takeuchi T, Morita R, Bai D, Ganesh S, Sugimoto Y, Inazawa J, Bailey JN, Ochoa A, Jara-Prado A, Rasmussen A, Ramos-Peek J, Cordova S, Rubio-Donnadieu F, Inoue Y, Osawa M, Kaneko S, Oguni H, Mori Y, Yamakawa K: Mutations in EFHC1 cause juvenile myoclonic epilepsy. Nat Genet. 2004.08; 36 (8): 842-849. ( PubMed , DOI )

Yokoi S, Yasui K, Mori M, Iizasa T, Fujisawa T, Inazawa J: Amplification and overexpression of SKP2 are associated with metastasis of non-small-cell lung cancers to lymph nodes. Am J Pathol. 2004.07; 165 (1): 175-180. ( PubMed , DOI )

Inoue J, Otsuki T, Hirasawa A, Imoto I, Matsuo Y, Shimizu S, Taniwaki M, Inazawa J: Overexpression of PDZK1 within the 1q12-q22 amplicon is likely to be associated with drug-resistance phenotype in multiple myeloma. Am J Pathol. 2004.07; 165 (1): 71-81. ( PubMed , DOI )

Inazawa J, Inoue J, Imoto I: Comparative genomic hybridization (CGH)-arrays pave the way for identification of novel cancer-related genes. Cancer science. 2004.07; 95 (7): 559-63. ( PubMed , DOI )

Tsutsumi S, Kamata N, Vokes TJ, Maruoka Y, Nakakuki K, Enomoto S, Omura K, Amagasa T, Nagayama M, Saito-Ohara F, Inazawa J, Moritani M, Yamaoka T, Inoue H, Itakura M: The novel gene encoding a putative transmembrane protein is mutated in gnathodiaphyseal dysplasia (GDD). Am J Hum Genet. 2004.06; 74 (6): 1255-1261. ( PubMed , DOI )

Yuki Y, Imoto I, Imaizumi M, Hibi S, Kaneko Y, Amagasa T, Inazawa J: Identification of a novel fusion gene in a pre-B acute lymphoblastic leukemia with t(1;19)(q23;p13). Cancer Sci. 2004.06; 95 (6): 503-507. ( PubMed )

Sonoda I, Imoto I, Inoue J, Shibata T, Shimada Y, Chin K, Imamura M, Amagasa T, Gray JW, Hirohashi S, Inazawa J: Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in esophageal squamous cell carcinoma. Cancer Res. 2004.06; 64 (11): 3741-3747. ( PubMed , DOI )

Sato H, Saito-Ohara F, Inazawa J, Kudo A: Pax-5 is essential for kappa sterile transcription during Ig kappa chain gene rearrangement. J Immunol. 2004.04; 172 (8): 4858-4865. ( PubMed )

Yasui K, Mihara S, Zhao C, Okamoto H, Saito-Ohara F, Tomida A, Funato T, Yokomizo A, Naito S, Imoto I, Tsuruo T, Inazawa J: Alteration in copy numbers of genes as a mechanism for acquired drug resistance. Cancer Res. 2004.02; 64 (4): 1403-1410. ( PubMed , DOI )

Misawa A, Hosoi H, Imoto I, Iehara T, Sugimoto T, Inazawa J: Translocation (1;22)(p36;q11.2) with concurrent del(22)(q11.2) resulted in homozygous deletion of SNF5/INI1 in a newly established cell line derived from extrarenal rhabdoid tumor. J Hum Genet. 2004; 49 (10): 586-589. ( PubMed , DOI )

Fujita Y, Sakakura C, Shimomura K, Nakanishi M, Yasuoka R, Aragane H, Hagiwara A, Abe T, Inazawa J, Yamagishi H: Chromosome arm 20q gains and other genomic alterations in esophageal squamous cell carcinoma, as analyzed by comparative genomic hybridization and fluorescence in situ hybridization. Hepatogastroenterology. 2003.11; 50 (54): 1857-1863. ( PubMed )

Hirasawa A, Aoki D, Inoue J, Imoto I, Susumu N, Sugano K, Nozawa S, Inazawa J: Unfavorable prognostic factors associated with high frequency of microsatellite instability and comparative genomic hybridization analysis in endometrial cancer. Clin Cancer Res. 2003.11; 9 (15): 5675-5682. ( PubMed )

Okamoto H, Yasui K, Zhao C, Arii S, Inazawa J: PTK2 and EIF3S3 genes may be amplification targets at 8q23-q24 and are associated with large hepatocellular carcinomas. Hepatology. 2003.11; 38 (5): 1242-1249. ( PubMed , DOI )

Yokoi S, Yasui K, Iizasa T, Imoto I, Fujisawa T, Inazawa J: TERC identified as a probable target within the 3q26 amplicon that is detected frequently in non-small cell lung cancers. Clin Cancer Res. 2003.10; 9 (13): 4705-4713. ( PubMed )

Imoto I, Yuki Y, Sonoda I, Ito T, Shimada Y, Imamura M, Inazawa J: Identification of ZASC1 encoding a Kruppel-like zinc finger protein as a novel target for 3q26 amplification in esophageal squamous cell carcinomas. Cancer Res. 2003.09; 63 (18): 5691-5696. ( PubMed )

Zhao C, Yasui K, Lee CJ, Kurioka H, Hosokawa Y, Oka T, Inazawa J: Elevated expression levels of NCOA3, TOP1, and TFAP2C in breast tumors as predictors of poor prognosis. Cancer. 2003.07; 98 (1): 18-23. ( PubMed , DOI )

Hirasawa A, Saito-Ohara F, Inoue J, Aoki D, Susumu N, Yokoyama T, Nozawa S, Inazawa J, Imoto I: Association of 17q21-q24 gain in ovarian clear cell adenocarcinomas with poor prognosis and identification of PPM1D and APPBP2 as likely amplification targets. Clin Cancer Res. 2003.06; 9 (6): 1995-2004. ( PubMed )

Hashimoto N, Murakami M, Takahashi Y, Fujimoto M, Inazawa J, Mineura K: Correlation between genetic alteration and long-term clinical outcome of patients with oligodendroglial tumors, with identification of a consistent region of deletion on chromosome arm 1p. Cancer. 2003.05; 97 (9): 2254-2261. ( PubMed , DOI )

Yokoi S, Yasui K, Iizasa T, Takahashi T, Fujisawa T, Inazawa J: Down-regulation of SKP2 induces apoptosis in lung-cancer cells. Cancer Sci. 2003.04; 94 (4): 344-349. ( PubMed , DOI )

Saito-Ohara F, Imoto I, Inoue J, Hosoi H, Nakagawara A, Sugimoto T, Inazawa J: PPM1D is a potential target for 17q gain in neuroblastoma. Cancer Res. 2003.04; 63 (8): 1876-1883. ( PubMed )

Shimada Y, Maeda M, Watanabe G, Yamasaki S, Komoto I, Kaganoi J, Kan T, Hashimoto Y, Imoto I, Inazawa J, Imamura M: Cell culture in esophageal squamous cell carcinoma and the association with molecular markers. Clin Cancer Res. 2003.01; 9 (1): 243-249. ( PubMed )

Murakami M, Hashimoto N, Takahashi Y, Hosokawa Y, Inazawa J, Mineura K: A consistent region of deletion on 1p36 in meningiomas: identification and relation to malignant progression. Cancer Genet Cytogenet. 2003.01; 140 (2): 99-106. ( PubMed )

Li M, Ishikawa K, Toru S, Tomimitsu H, Takashima M, Goto J, Takiyama Y, Sasaki H, Imoto I, Inazawa J, Toda T, Kanazawa I, Mizusawa H: Physical map and haplotype analysis of 16q-linked autosomal dominant cerebellar ataxia (ADCA) type III in Japan. J Hum Genet. 2003; 48 (3): 111-118. ( PubMed , DOI )

Yasui K, Okamoto H, Arii S, Inazawa J: Association of over-expressed TFDP1 with progression of hepatocellular carcinomas. J Hum Genet. 2003; 48 (12): 609-613. ( PubMed , DOI )

Yu W, Inoue J, Imoto I, Matsuo Y, Karpas A, Inazawa J: GPC5 is a possible target for the 13q31-q32 amplification detected in lymphoma cell lines. J Hum Genet. 2003; 48 (6): 331-335. ( PubMed , DOI )

Watanabe T, Imoto I, Katahira T, Hirasawa A, Ishiwata I, Emi M, Takayama M, Sato A, Inazawa J: Differentially regulated genes as putative targets of amplifications at 20q in ovarian cancers. Jpn J Cancer Res. 2002.10; 93 (10): 1114-1122. ( PubMed , DOI )

Okamoto R, Yajima T, Yamazaki M, Kanai T, Mukai M, Okamoto S, Ikeda Y, Hibi T, Inazawa J, Watanabe M: Damaged epithelia regenerated by bone marrow-derived cells in the human gastrointestinal tract. Nat Med. 2002.09; 8 (9): 1011-1017. ( PubMed , DOI )

Saito-Ohara F, Fukuda Y, Ito M, Agarwala KL, Hayashi M, Matsuo M, Imoto I, Yamakawa K, Nakamura Y, Inazawa J: The Xq22 inversion breakpoint interrupted a novel Ras-like GTPase gene in a patient with Duchenne muscular dystrophy and profound mental retardation. Am J Hum Genet. 2002.09; 71 (3): 637-645. ( PubMed , DOI )

Imoto I, Tsuda H, Hirasawa A, Miura M, Sakamoto M, Hirohashi S, Inazawa J: Expression of cIAP1, a target for 11q22 amplification, correlates with resistance of cervical cancers to radiotherapy. Cancer Res. 2002.09; 62 (17): 4860-4866. ( PubMed )

Imiya K, Ishizaki T, Seiki T, Saito F, Inazawa J, Oka S, Kawasaki T: cDNA cloning, genomic structure and chromosomal mapping of the mouse glucuronyltransferase-S involved in the biosynthesis of the HNK-1 carbohydrate epitope. Gene. 2002.08; 296 (1-2): 29-36. ( PubMed )

Suzuki T, Morita R, Sugimoto Y, Sugawara T, Bai DS, Alonso ME, Medina MT, Bailey JN, Rasmussen A, Ramos-Peek J, Cordova S, Rubio-Donnadieu F, Ochoa A, Jara-Prado A, Inazawa J, Delgado-Escueta AV, Yamakawa K: Identification and mutational analysis of candidate genes for juvenile myoclonic epilepsy on 6p11-p12: LRRC1, GCLC, KIAA0057 and CLIC5. Epilepsy Res. 2002.08; 50 (3): 265-275. ( PubMed )

Yokoi S, Yasui K, Saito-Ohara F, Koshikawa K, Iizasa T, Fujisawa T, Terasaki T, Horii A, Takahashi T, Hirohashi S, Inazawa J: A novel target gene, SKP2, within the 5p13 amplicon that is frequently detected in small cell lung cancers. Am J Pathol. 2002.07; 161 (1): 207-216. ( PubMed , DOI )

Hashimoto Y, Zhang C, Kawauchi J, Imoto I, Adachi MT, Inazawa J, Amagasa T, Hai T, Kitajima S: An alternatively spliced isoform of transcriptional repressor ATF3 and its induction by stress stimuli. Nucleic Acids Res. 2002.06; 30 (11): 2398-2406. ( PubMed )

Yasui K, Arii S, Zhao C, Imoto I, Ueda M, Nagai H, Emi M, Inazawa J: TFDP1, CUL4A, and CDC16 identified as targets for amplification at 13q34 in hepatocellular carcinomas. Hepatology. 2002.06; 35 (6): 1476-1484. ( PubMed , DOI )

Chano T, Ikegawa S, Saito-Ohara F, Inazawa J, Mabuchi A, Saeki Y, Okabe H: Isolation, characterization and mapping of the mouse and human RB1CC1 genes. Gene. 2002.05; 291 (1-2): 29-34. ( PubMed )

Ikeda A, Sakuma H, Masaki M, Kozutsumi Y, Oka S, Inazawa J, Kawasaki T: Genomic organization and fine-mapping of the human leucine zipper-bearing kinase (LZK) gene. J Biochem Mol Biol Biophys. 2002.04; 6 (2): 113-117. ( PubMed , DOI )

Li QL, Ito K, Sakakura C, Fukamachi H, Inoue Ki, Chi XZ, Lee KY, Nomura S, Lee CW, Han SB, Kim HM, Kim WJ, Yamamoto H, Yamashita N, Yano T, Ikeda T, Itohara S, Inazawa J, Abe T, Hagiwara A, Yamagishi H, Ooe A, Kaneda A, Sugimura T, Ushijima T, Bae SC, Ito Y: Causal relationship between the loss of RUNX3 expression and gastric cancer. Cell. 2002.04; 109 (1): 113-124. ( PubMed )

Yamamoto S, Oka S, Saito-Ohara F, Inazawa J, Kawasaki T: Molecular cloning and genomic analysis of mouse glucuronyltransferase involved in biosynthesis of the HNK-1 epitope. J Biochem. 2002.03; 131 (3): 337-347. ( PubMed )

Nakakuki K, Imoto I, Pimkhaokham A, Fukuda Y, Shimada Y, Imamura M, Amagasa T, Inazawa J: Novel targets for the 18p11.3 amplification frequently observed in esophageal squamous cell carcinomas. Carcinogenesis. 2002.01; 23 (1): 19-24. ( PubMed )

Janssen JW, Imoto I, Inoue J, Shimada Y, Ueda M, Imamura M, Bartram CR, Inazawa J: MYEOV, a gene at 11q13, is coamplified with CCND1, but epigenetically inactivated in a subset of esophageal squamous cell carcinomas. J Hum Genet. 2002; 47 (9): 460-464. ( PubMed , DOI )

Aragane H, Sakakura C, Nakanishi M, Yasuoka R, Fujita Y, Taniguchi H, Hagiwara A, Yamaguchi T, Abe T, Inazawa J, Yamagishi H: Chromosomal aberrations in colorectal cancers and liver metastases analyzed by comparative genomic hybridization. Int J Cancer. 2001.12; 94 (5): 623-629. ( PubMed )

Suzuki T, Ganesh S, Agarwala KL, Morita R, Sugimoto Y, Inazawa J, Delgado-Escueta AV, Yamakawa K: A novel gene in the chromosomal region for juvenile myoclonic epilepsy on 6p12 encodes a brain-specific lysosomal membrane protein. Biochem Biophys Res Commun. 2001.11; 288 (3): 626-636. ( PubMed , DOI )

Yasui K, Imoto I, Fukuda Y, Pimkhaokham A, Yang ZQ, Naruto T, Shimada Y, Nakamura Y, Inazawa J: Identification of target genes within an amplicon at 14q12-q13 in esophageal squamous cell carcinoma. Genes Chromosomes Cancer. 2001.10; 32 (2): 112-118. ( PubMed )

Terada Y, Imoto I, Nagai H, Suwa K, Momoi M, Tajiri T, Onda M, Inazawa J, Emi M: An 8-cM interstitial deletion on 4q21-q22 in DNA from an infant with hepatoblastoma overlaps with a commonly deleted region in adult liver cancers. Am J Med Genet. 2001.10; 103 (2): 176-180. ( PubMed )

Imoto I, Yang ZQ, Pimkhaokham A, Tsuda H, Shimada Y, Imamura M, Ohki M, Inazawa J: Identification of cIAP1 as a candidate target gene within an amplicon at 11q22 in esophageal squamous cell carcinomas. Cancer Res. 2001.09; 61 (18): 6629-6634. ( PubMed )

Imoto I, Sonoda I, Yuki Y, Inazawa J: Identification and characterization of human PKNOX2, a novel homeobox-containing gene. Biochem Biophys Res Commun. 2001.09; 287 (1): 270-276. ( PubMed , DOI )

Imoto I, Pimkhaokham A, Fukuda Y, Yang ZQ, Shimada Y, Nomura N, Hirai H, Imamura M, Inazawa J: SNO is a probable target for gene amplification at 3q26 in squamous-cell carcinomas of the esophagus. Biochem Biophys Res Commun. 2001.08; 286 (3): 559-565. ( PubMed , DOI )

Baba T, Mimura J, Gradin K, Kuroiwa A, Watanabe T, Matsuda Y, Inazawa J, Sogawa K, Fujii-Kuriyama Y: Structure and expression of the Ah receptor repressor gene. J Biol Chem. 2001.08; 276 (35): 33101-33110. ( PubMed , DOI )

Chen YZ, Soeda E, Yang HW, Takita J, Chai L, Horii A, Inazawa J, Ohki M, Hayashi Y: Homozygous deletion in a neuroblastoma cell line defined by a high-density STS map spanning human chromosome band 1p36. Genes Chromosomes Cancer. 2001.08; 31 (4): 326-332. ( PubMed , DOI )

Chen YZ, Hayashi Y, Wu JG, Takaoka E, Maekawa K, Watanabe N, Inazawa J, Hosoda F, Arai Y, Ohki M, Mizushima H, Morohashi A, Ohira M, Nakagawara A, Liu SY, Hoshi M, Horii A, Soeda E: A BAC-based STS-content map spanning a 35-Mb region of human chromosome 1p35-p36. Genomics. 2001.05; 74 (1): 55-70. ( PubMed , DOI )

Watanabe T, Imoto I, Kosugi Y, Ishiwata I, Inoue S, Takayama M, Sato A, Inazawa J: A novel amplification at 17q21-23 in ovarian cancer cell lines detected by comparative genomic hybridization. Gynecol Oncol. 2001.05; 81 (2): 172-177. ( PubMed , DOI )

Yang ZQ, Imoto I, Pimkhaokham A, Shimada Y, Sasaki K, Oka M, Inazawa J: A novel amplicon at 9p23 - 24 in squamous cell carcinoma of the esophagus that lies proximal to GASC1 and harbors NFIB. Jpn J Cancer Res. 2001.04; 92 (4): 423-428. ( PubMed )

Tsukamoto F, Miyoshi Y, Egawa C, Kasugai T, Takami S, Inazawa J, Noguchi S: Clinicopathologic analysis of breast carcinoma with chromosomal aneusomy detected by fluorescence in situ hybridization. Cancer. 2001.04; 93 (2): 165-170. ( PubMed )

Sakakura C, Hagiwara A, Yasuoka R, Fujita Y, Nakanishi M, Masuda K, Shimomura K, Nakamura Y, Inazawa J, Abe T, Yamagishi H: Tumour-amplified kinase BTAK is amplified and overexpressed in gastric cancers with possible involvement in aneuploid formation. Br J Cancer. 2001.03; 84 (6): 824-831. ( PubMed , DOI )

Kojya S, Matsumura J, Ting L, Hongyo T, Inazawa J, Kirihata M, Aozasa K: Familial nasal NK/T-cell lymphoma and pesticide use. Am J Hematol. 2001.02; 66 (2): 145-147. ( PubMed , DOI )

Watanabe T, Imoto I, Kosugi Y, Fukuda Y, Mimura J, Fujii Y, Isaka K, Takayama M, Sato A, Inazawa J: Human arylhydrocarbon receptor repressor (AHRR) gene: genomic structure and analysis of polymorphism in endometriosis. J Hum Genet. 2001; 46 (6): 342-346. ( PubMed , DOI )

Harada H, Nagai H, Mine N, Terada Y, Fujiwara H, Mikami I, Tsuneizumi M, Yabe A, Miyazaki K, Yokota T, Imoto I, Inazawa J, Emi M: Molecular cloning, tissue expression, and chromosomal assignment of a novel gene encoding a subunit of the human signal-recognition particle. J Hum Genet. 2001; 46 (2): 70-75. ( PubMed , DOI )

Yoshida S, Fukino K, Harada H, Nagai H, Imoto I, Inazawa J, Takahashi H, Teramoto A, Emi M: The c-Jun NH2-terminal kinase3 (JNK3) gene: genomic structure, chromosomal assignment, and loss of expression in brain tumors. J Hum Genet. 2001; 46 (4): 182-187. ( PubMed , DOI )

Sugimoto N, Imoto I, Fukuda Y, Kurihara N, Kuroda S, Tanigami A, Kaibuchi K, Kamiyama R, Inazawa J: IQGAP1, a negative regulator of cell-cell adhesion, is upregulated by gene amplification at 15q26 in gastric cancer cell lines HSC39 and 40A. J Hum Genet. 2001; 46 (1): 21-25. ( PubMed , DOI )

Tsukamoto F, Miyoshi Y, Koyama H, Watatani M, Sasa M, Shiba E, Takami S, Inazawa J, Noguchi S: Detection of chromosomal aneusomy by fluorescence in situ hybridization in fine-needle aspirates from breast tumors: application to the preoperative diagnosis of breast carcinoma. Cancer. 2000.12; 90 (6): 373-378. ( PubMed )

Fukuda Y, Kurihara N, Imoto I, Yasui K, Yoshida M, Yanagihara K, Park JG, Nakamura Y, Inazawa J: CD44 is a potential target of amplification within the 11p13 amplicon detected in gastric cancer cell lines. Genes Chromosomes Cancer. 2000.12; 29 (4): 315-324. ( PubMed )

Nakagawara A, Ohira M, Kageyama H, Mihara M, Furuta S, Machida T, Takayasu H, Islam A, Nakamura Y, Takahashi M, Shishikura T, Kaneko Y, Toyoda A, Hattori M, Sakaki Y, Ohki M, Horii A, Soeda E, Inazawa J, Seki N, Kuma H, Nozawa I, Sakiyama S: Identification of the homozygously deleted region at chromosome 1p36.2 in human neuroblastoma. Med Pediatr Oncol. 2000.12; 35 (6): 516-521. ( PubMed )

Pimkhaokham A, Shimada Y, Fukuda Y, Kurihara N, Imoto I, Yang ZQ, Imamura M, Nakamura Y, Amagasa T, Inazawa J: Nonrandom chromosomal imbalances in esophageal squamous cell carcinoma cell lines: possible involvement of the ATF3 and CENPF genes in the 1q32 amplicon. Jpn J Cancer Res. 2000.11; 91 (11): 1126-1133. ( PubMed )

Uchida S, Tanaka Y, Ito H, Saitoh-Ohara F, Inazawa J, Yokoyama KK, Sasaki S, Marumo F: Transcriptional regulation of the CLC-K1 promoter by myc-associated zinc finger protein and kidney-enriched Kruppel-like factor, a novel zinc finger repressor. Mol Cell Biol. 2000.10; 20 (19): 7319-7331. ( PubMed )

Koide K, Sakakura C, Hagiwara A, Yamaguchi T, Yamagishi H, Abe T, Inazawa J: An improved rapid procedure for fluorescence in situ hybridization that is applicable to intraoperative cancer cytodiagnosis. Cancer Lett. 2000.10; 158 (2): 165-169. ( PubMed )

Yang ZQ, Imoto I, Fukuda Y, Pimkhaokham A, Shimada Y, Imamura M, Sugano S, Nakamura Y, Inazawa J: Identification of a novel gene, GASC1, within an amplicon at 9p23-24 frequently detected in esophageal cancer cell lines. Cancer Res. 2000.09; 60 (17): 4735-4739. ( PubMed )

Imoto I, Pimkhaokham A, Watanabe T, Saito-Ohara F, Soeda E, Inazawa J: Amplification and overexpression of TGIF2, a novel homeobox gene of the TALE superclass, in ovarian cancer cell lines. Biochem Biophys Res Commun. 2000.09; 276 (1): 264-270. ( PubMed , DOI )

Ohira M, Kageyama H, Mihara M, Furuta S, Machida T, Shishikura T, Takayasu H, Islam A, Nakamura Y, Takahashi M, Tomioka N, Sakiyama S, Kaneko Y, Toyoda A, Hattori M, Sakaki Y, Ohki M, Horii A, Soeda E, Inazawa J, Seki N, Kuma H, Nozawa I, Nakagawara A: Identification and characterization of a 500-kb homozygously deleted region at 1p36.2-p36.3 in a neuroblastoma cell line. Oncogene. 2000.08; 19 (37): 4302-4307. ( PubMed , DOI )

Sasaki S, Ito E, Toki T, Maekawa T, Kanezaki R, Umenai T, Muto A, Nagai H, Kinoshita T, Yamamoto M, Inazawa J, Taketo MM, Nakahata T, Igarashi K, Yokoyama M: Cloning and expression of human B cell-specific transcription factor BACH2 mapped to chromosome 6q15. Oncogene. 2000.08; 19 (33): 3739-3749. ( PubMed , DOI )

Ueno M, Kimura N, Nakashima K, Saito-Ohara F, Inazawa J, Taga T: Genomic organization, sequence and chromosomal localization of the mouse Tbr2 gene and a comparative study with Tbr1. Gene. 2000.08; 254 (1-2): 29-35. ( PubMed )

Ikeda K, Sato M, Tsutsumi O, Tsuchiya F, Tsuneizumi M, Emi M, Imoto I, Inazawa J, Muramatsu M, Inoue S: Promoter analysis and chromosomal mapping of human EBAG9 gene. Biochem Biophys Res Commun. 2000.07; 273 (2): 654-660. ( PubMed , DOI )

Ohki R, Nemoto J, Murasawa H, Oda E, Inazawa J, Tanaka N, Taniguchi T: Reprimo, a new candidate mediator of the p53-mediated cell cycle arrest at the G2 phase. J Biol Chem. 2000.07; 275 (30): 22627-22630. ( PubMed , DOI )

Sakakura C, Hagiwara A, Yasuoka R, Fujita Y, Nakanishi M, Masuda K, Kimura A, Nakamura Y, Inazawa J, Abe T, Yamagishi H: Amplification and over-expression of the AIB1 nuclear receptor co-activator gene in primary gastric cancers. Int J Cancer. 2000.05; 89 (3): 217-223. ( PubMed )

Nakanishi M, Sakakura C, Fujita Y, Yasuoka R, Aragane H, Koide K, Hagiwara A, Yamaguchi T, Nakamura Y, Abe T, Inazawa J, Yamagishi H: Genomic alterations in primary gastric cancers analyzed by comparative genomic hybridization and clinicopathological factors. Hepatogastroenterology. 2000.05; 47 (33): 658-662. ( PubMed )

Mitsumoto Y, Oka S, Sakuma H, Inazawa J, Kawasaki T: Cloning and chromosomal mapping of human glucuronyltransferase involved in biosynthesis of the HNK-1 carbohydrate epitope. Genomics. 2000.04; 65 (2): 166-173. ( PubMed , DOI )

Iida A, Emi M, Matsuoka R, Hiratsuka E, Okui K, Ohashi H, Inazawa J, Fukushima Y, Imai T, Nakamura Y: Identification of a gene disrupted by inv(11)(q13.5;q25) in a patient with left-right axis malformation. Hum Genet. 2000.03; 106 (3): 277-287. ( PubMed )

Yang ZQ, Yoshida MA, Fukuda Y, Kurihara N, Nakamura Y, Inazawa J: Molecular cytogenetic analysis of 17 renal cancer cell lines: increased copy number at 5q31-33 in cell lines from nonpapillary carcinomas. Jpn J Cancer Res. 2000.02; 91 (2): 156-163. ( PubMed )

Suzuki T, Nishiyama K, Yamamoto A, Inazawa J, Iwaki T, Yamada T, Kanazawa I, Sakaki Y: Molecular cloning of a novel apoptosis-related gene, human Nap1 (NCKAP1), and its possible relation to Alzheimer disease. Genomics. 2000.01; 63 (2): 246-254. ( PubMed , DOI )

Meng G, Inazawa J, Ishida R, Tokura K, Nakahara K, Aoki K, Kasai M: Structural analysis of the gene encoding RP58, a sequence-specific transrepressor associated with heterochromatin. Gene. 2000.01; 242 (1-2): 59-64. ( PubMed )

Meng G, Aoki K, Tokura K, Nakahara K, Inazawa J, Kasai M: Genomic structure and chromosomal localization of the gene encoding TRAX, a Translin-associated factor X. J Hum Genet. 2000; 45 (5): 305-308. ( PubMed , DOI )

Yokota T, Nakata T, Minami S, Inazawa J, Emi M: Genomic organization and chromosomal mapping of ELKS, a gene rearranged in a papillary thyroid carcinoma. J Hum Genet. 2000; 45 (1): 6-11. ( PubMed , DOI )

Nakajima T, Iwaki K, Kodama T, Inazawa J, Emi M: Genomic structure and chromosomal mapping of the human site-1 protease (S1P) gene. J Hum Genet. 2000; 45 (4): 212-217. ( PubMed , DOI )

Kohro T, Nakajima T, Wada Y, Sugiyama A, Ishii M, Tsutsumi S, Aburatani H, Imoto I, Inazawa J, Hamakubo T, Kodama T, Emi M: Genomic structure and mapping of human orphan receptor LXR alpha: upregulation of LXRa mRNA during monocyte to macrophage differentiation. J Atheroscler Thromb. 2000; 7 (3): 145-151. ( PubMed )

Kakazu N, Taniwaki M, Horiike S, Nishida K, Tatekawa T, Nagai M, Takahashi T, Akaogi T, Inazawa J, Ohki M, Abe T: Combined spectral karyotyping and DAPI banding analysis of chromosome abnormalities in myelodysplastic syndrome. Genes Chromosomes Cancer. 1999.12; 26 (4): 336-345. ( PubMed )

Lee JH, Takahashi T, Yasuhara N, Inazawa J, Kamada S, Tsujimoto Y: Bis, a Bcl-2-binding protein that synergizes with Bcl-2 in preventing cell death. Oncogene. 1999.11; 18 (46): 6183-6190. ( PubMed , DOI )

Yasuno T, Matsumura T, Shikata T, Inazawa J, Sakabe T, Tsuchida S, Takahata T, Miyairi S, Naganuma A, Sawada T: Establishment and characterization of a cisplatin-resistant human neuroblastoma cell line. Anticancer Res. 1999.09; 19 (5B): 4049-4057. ( PubMed )

Sakakura C, Hagiwara A, Shirahama T, Nakanishi M, Yasuoka R, Fujita Y, Inazawa J, Abe T, Kohno M, Yamagishi H: Infrequent activation of mitogen-activated protein kinase in human colon cancers. Hepatogastroenterology. 1999.09; 46 (29): 2831-2834. ( PubMed )

Sakakura C, Hagiwara A, Taniguchi H, Yamaguchi T, Yamagishi H, Takahashi T, Koyama K, Nakamura Y, Abe T, Inazawa J: Chromosomal aberrations in human hepatocellular carcinomas associated with hepatitis C virus infection detected by comparative genomic hybridization. Br J Cancer. 1999.08; 80 (12): 2034-2039. ( PubMed , DOI )

Osaki E, Nishina Y, Inazawa J, Copeland NG, Gilbert DJ, Jenkins NA, Ohsugi M, Tezuka T, Yoshida M, Semba K: Identification of a novel Sry-related gene and its germ cell-specific expression. Nucleic Acids Res. 1999.06; 27 (12): 2503-2510. ( PubMed )

Murata H, Kusuzaki K, Hirasawa Y, Ashihara T, Abe T, Inazawa J: Relationship between chromosomal aberrations by fluorescence in situ hybridization and DNA ploidy by cytofluorometry in osteosarcoma. Cancer Lett. 1999.05; 139 (2): 221-226. ( PubMed )

Shinomiya T, Mori T, Ariyama Y, Sakabe T, Fukuda Y, Murakami Y, Nakamura Y, Inazawa J: Comparative genomic hybridization of squamous cell carcinoma of the esophagus: the possible involvement of the DPI gene in the 13q34 amplicon. Genes Chromosomes Cancer. 1999.04; 24 (4): 337-344. ( PubMed )

Sakakura C, Mori T, Sakabe T, Ariyama Y, Shinomiya T, Date K, Hagiwara A, Yamaguchi T, Takahashi T, Nakamura Y, Abe T, Inazawa J: Gains, losses, and amplifications of genomic materials in primary gastric cancers analyzed by comparative genomic hybridization. Genes Chromosomes Cancer. 1999.04; 24 (4): 299-305. ( PubMed )

Sakabe T, Shinomiya T, Mori T, Ariyama Y, Fukuda Y, Fujiwara T, Nakamura Y, Inazawa J: Identification of a novel gene, MASL1, within an amplicon at 8p23.1 detected in malignant fibrous histiocytomas by comparative genomic hybridization. Cancer Res. 1999.02; 59 (3): 511-515. ( PubMed )

Mori T, Fukuda Y, Kuroda H, Matsumura T, Ota S, Sugimoto T, Nakamura Y, Inazawa J: Cloning and characterization of a novel Rab-family gene, Rab36, within the region at 22q11.2 that is homozygously deleted in malignant rhabdoid tumors. Biochem Biophys Res Commun. 1999.01; 254 (3): 594-600. ( PubMed , DOI )

Oda K, Shiratsuchi T, Nishimori H, Inazawa J, Yoshikawa H, Taketani Y, Nakamura Y, Tokino T: Identification of BAIAP2 (BAI-associated protein 2), a novel human homologue of hamster IRSp53, whose SH3 domain interacts with the cytoplasmic domain of BAI1. Cytogenet Cell Genet. 1999; 84 (1-2): 75-82. ( PubMed )

Nakajima T, Hamakubo T, Kodama T, Inazawa J, Emi M: Genomic structure and chromosomal mapping of the human sterol regulatory element binding protein (SREBP) cleavage-activating protein (SCAP) gene. J Hum Genet. 1999; 44 (6): 402-407. ( PubMed , DOI )

Baba Y, Matsushita M, Matsuda Y, Inazawa J, Yamadori T, Hashimoto S, Kishimoto T, Tsukada S: Assignment of SH3BP5/Sh3bp5 encoding sab, an SH3 domain-binding protein which preferentially associates with Bruton's tyrosine kinase, to human chromosome 1q43 and mouse chromosome 14B by in situ hybridization. Cytogenet Cell Genet. 1999; 87 (3-4): 221-222. ( PubMed )

Sugimoto N, Fukuda Y, Saito-Ohara F, Kamiyama R, Nakagawara A, Mukae N, Nagata S, Inazawa J: The human caspase-activated DNase gene (hCAD): genomic structure, exonic single-nucleotide polymorphisms, and a highly polymorphic dinucleotide repeat at the hCAD locus. J Hum Genet. 1999; 44 (6): 408-411. ( PubMed , DOI )

Miura K, Miyoshi O, Yun K, Inazawa J, Miyamoto T, Hayashi H, Masuzaki H, Yoshimura S, Niikawa N, Jinno Y, Ishimaru T: Repeat-directed isolation of a novel gene preferentially expressed from the maternal allele in human placenta. J Hum Genet. 1999; 44 (1): 1-9. ( PubMed , DOI )

Ariyama Y, Mori T, Shinomiya T, Sakabe T, Fukuda Y, Kanamaru A, Yamada Y, Isobe M, Seto M, Nakamura Y, Inazawa J: Chromosomal imbalances in adult T-cell leukemia revealed by comparative genomic hybridization: gains at 14q32 and 2p16-22 in cell lines. J Hum Genet. 1999; 44 (6): 357-363. ( PubMed , DOI )

Noto S, Maeda T, Hattori S, Inazawa J, Imamura M, Asaka M, Hatakeyama M: A novel human RasGAP-like gene that maps within the prostate cancer susceptibility locus at chromosome 1q25. FEBS Lett. 1998.12; 441 (1): 127-131. ( PubMed )

Murata H, Kusuzaki K, Takeshita H, Hirasawa Y, Ashihara T, Abe T, Inazawa J: Aberrations of chromosomes 1 and 17 in six human osteosarcoma cell lines using double-target fluorescence in situ hybridization. Cancer Genet Cytogenet. 1998.11; 107 (1): 7-10. ( PubMed )

Ariyama Y, Fukuda Y, Okuno Y, Seto M, Date K, Abe T, Nakamura Y, Inazawa J: Amplification on double-minute chromosomes and partial-tandem duplication of the MLL gene in leukemic cells of a patient with acute myelogenous leukemia. Genes Chromosomes Cancer. 1998.11; 23 (3): 267-272. ( PubMed )

Mukae N, Enari M, Sakahira H, Fukuda Y, Inazawa J, Toh H, Nagata S: Molecular cloning and characterization of human caspase-activated DNase. Proc Natl Acad Sci U S A. 1998.08; 95 (16): 9123-9128. ( PubMed )

Ishino S, Hashimoto N, Fushiki S, Date K, Mori T, Fujimoto M, Nakagawa Y, Ueda S, Abe T, Inazawa J: Loss of material from chromosome arm 1p during malignant progression of meningioma revealed by fluorescent in situ hybridization. Cancer. 1998.07; 83 (2): 360-366. ( PubMed )

Mano H, Ohya K, Miyazato A, Yamashita Y, Ogawa W, Inazawa J, Ikeda U, Shimada K, Hatake K, Kasuga M, Ozawa K, Kajigaya S: Grb10/GrbIR as an in vivo substrate of Tec tyrosine kinase. Genes Cells. 1998.07; 3 (7): 431-441. ( PubMed )

Nakada Y, Taniura H, Uetsuki T, Inazawa J, Yoshikawa K: The human chromosomal gene for necdin, a neuronal growth suppressor, in the Prader-Willi syndrome deletion region. Gene. 1998.06; 213 (1-2): 65-72. ( PubMed )

Yoshida Y, Matsuda S, Ikematsu N, Kawamura-Tsuzuku J, Inazawa J, Umemori H, Yamamoto T: ANA, a novel member of Tob/BTG1 family, is expressed in the ventricular zone of the developing central nervous system. Oncogene. 1998.05; 16 (20): 2687-2693. ( PubMed , DOI )

Yoshikawa H, Fujiyama A, Nakai K, Inazawa J, Matsubara K: Detection and isolation of a novel human gene located on Xp11.2-p11.4 that escapes X-inactivation using a two-dimensional DNA mapping method. Genomics. 1998.04; 49 (2): 237-246. ( PubMed , DOI )

Matsushita M, Yamadori T, Kato S, Takemoto Y, Inazawa J, Baba Y, Hashimoto S, Sekine S, Arai S, Kunikata T, Kurimoto M, Kishimoto T, Tsukada S: Identification and characterization of a novel SH3-domain binding protein, Sab, which preferentially associates with Bruton's tyrosine kinase (BtK). Biochem Biophys Res Commun. 1998.04; 245 (2): 337-343. ( PubMed , DOI )

Kohno T, Kawanishi M, Inazawa J, Yokota J: Identification of CpG islands hypermethylated in human lung cancer by the arbitrarily primed-PCR method. Hum Genet. 1998.03; 102 (3): 258-264. ( PubMed )

Yoshida H, Kondo M, Ichihashi T, Hashimoto N, Inazawa J, Ohno R, Naoe T: A novel myeloid cell line, Marimo, derived from therapy-related acute myeloid leukemia during treatment of essential thrombocythemia: consistent chromosomal abnormalities and temporary C-MYC gene amplification. Cancer Genet Cytogenet. 1998.01; 100 (1): 21-24. ( PubMed )

Ariyama Y, Sakabe T, Shinomiya T, Mori T, Fukuda Y, Inazawa J: Identification of amplified DNA sequences on double minute chromosomes in a leukemic cell line KY821 by means of spectral karyotyping and comparative genomic hybridization. J Hum Genet. 1998; 43 (3): 187-190. ( PubMed , DOI )

Sakakura C, Koide K, Ichikawa D, Wakasa T, Shirasu M, Kimura A, Taniguchi H, Hagiwara A, Yamaguchi T, Inazawa J, Abe T, Takahashi T, Otsuji E: Analysis of histological therapeutic effect, apoptosis rate and p53 status after combined treatment with radiation, hyperthermia and 5-fluorouracil suppositories for advanced rectal cancers. Br J Cancer. 1998; 77 (1): 159-166. ( PubMed )

Tsuda H, Takarabe T, Inazawa J, Hirohashi S: Detection of Numerical Alterations of Chromosomes 3, 7, 17 and X in Low-grade Intracystic Papillary Tumors of the Breast by Multi-color Fluorescence In Situ Hybridization. Breast Cancer. 1997.12; 4 (4): 247-252. ( PubMed )

Fukuta M, Inazawa J, Torii T, Tsuzuki K, Shimada E, Habuchi O: Molecular cloning and characterization of human keratan sulfate Gal-6-sulfotransferase. J Biol Chem. 1997.12; 272 (51): 32321-32328. ( PubMed )

Shimizu-Matsumoto A, Adachi W, Mizuno K, Inazawa J, Nishida K, Kinoshita S, Matsubara K, Okubo K: An expression profile of genes in human retina and isolation of a complementary DNA for a novel rod photoreceptor protein. Invest Ophthalmol Vis Sci. 1997.11; 38 (12): 2576-2585. ( PubMed )

Tanaka M, Tanaka T, Inazawa J, Nagafuchi S, Mutsui Y, Kaukas A, Johnston DA, Rollinson D: Proceedings of the schistosome genome project. Mem Inst Oswaldo Cruz. 1997.11; 92 (6): 829-834. ( PubMed )

Tsuda H, Takarabe T, Susumu N, Inazawa J, Okada S, Hirohashi S: Detection of numerical and structural alterations and fusion of chromosomes 16 and 1 in low-grade papillary breast carcinoma by fluorescence in situ hybridization. Am J Pathol. 1997.10; 151 (4): 1027-1034. ( PubMed )

Ishino M, Ohba T, Inazawa J, Sasaki H, Ariyama Y, Sasaki T: Identification of an Efs isoform that lacks the SH3 domain and chromosomal mapping of human Efs. Oncogene. 1997.10; 15 (14): 1741-1745. ( PubMed , DOI )

Murata H, Kusuzaki K, Hirasawa Y, Inazawa J, Abe T, Ashihara T: Ploidy analysis in paraffin-embedded malignant fibrous histiocytoma by DNA cytofluorometry and flourescence in situ hybridization. Cancer Lett. 1997.09; 118 (1): 123-128. ( PubMed )

Houri T, Hashimoto N, Ibayashi N, Mori T, Fujimoto M, Ueda S, Abe T, Inazawa J: Chromosomal translocation, t(1;11)(q12;p15), in an extragonadal immature teratoma. Cancer Genet Cytogenet. 1997.08; 97 (1): 79-80. ( PubMed )

Aoki K, Inazawa J, Takahashi T, Nakahara K, Kasai M: Genomic structure and chromosomal localization of the gene encoding translin, a recombination hotspot binding protein. Genomics. 1997.07; 43 (2): 237-241. ( PubMed , DOI )

Saitou M, Ando-Akatsuka Y, Itoh M, Furuse M, Inazawa J, Fujimoto K, Tsukita S: Mammalian occludin in epithelial cells: its expression and subcellular distribution. Eur J Cell Biol. 1997.07; 73 (3): 222-231. ( PubMed )

Hashimoto T, Inazawa J, Okamoto N, Tagawa Y, Bessho Y, Honda Y, Nakanishi S: The whole nucleotide sequence and chromosomal localization of the gene for human metabotropic glutamate receptor subtype 6. Eur J Neurosci. 1997.06; 9 (6): 1226-1235. ( PubMed )

Hosoda F, Arai Y, Kitamura E, Inazawa J, Fukushima M, Tokino T, Nakamura Y, Jones C, Kakazu N, Abe T, Ohki M: A complete NotI restriction map covering the entire long arm of human chromosome 11. Genes Cells. 1997.05; 2 (5): 345-357. ( PubMed )

Spicer AP, Seldin MF, Olsen AS, Brown N, Wells DE, Doggett NA, Itano N, Kimata K, Inazawa J, McDonald JA: Chromosomal localization of the human and mouse hyaluronan synthase genes. Genomics. 1997.05; 41 (3): 493-497. ( PubMed , DOI )

Kimura T, Arakawa Y, Inoue S, Fukushima Y, Kondo I, Koyama K, Hosoi T, Orimo A, Muramatsu M, Nakamura Y, Abe T, Inazawa J: The brain finger protein gene (ZNF179), a member of the RING finger family, maps within the Smith-Magenis syndrome region at 17p11.2. Am J Med Genet. 1997.03; 69 (3): 320-324. ( PubMed )

Shimotake T, Iwai N, Inoue K, Kimura T, Ichikawa D, Abe T, Inazawa J: Germline mutation of the RET proto-oncogene in children with total intestinal aganglionosis. J Pediatr Surg. 1997.03; 32 (3): 498-500. ( PubMed )

Saito H, Nakatsuru S, Inazawa J, Nishihira T, Park JG, Nakamura Y: Frequent association of alternative splicing of NER, a nuclear hormone receptor gene in cancer tissues. Oncogene. 1997.02; 14 (5): 617-621. ( PubMed , DOI )

Yasojima K, Tsujimura A, Mizuno T, Shigeyoshi Y, Inazawa J, Kikuno R, Kuma K, Ohkubo K, Hosokawa Y, Ibata Y, Abe T, Miyata T, Matsubara K, Nakajima K, Hashimoto-Gotoh T: Cloning of human and mouse cDNAs encoding novel zinc finger proteins expressed in cerebellum and hippocampus. Biochem Biophys Res Commun. 1997.02; 231 (2): 481-487. ( PubMed )

Nakai A, Tanabe M, Kawazoe Y, Inazawa J, Morimoto RI, Nagata K: HSF4, a new member of the human heat shock factor family which lacks properties of a transcriptional activator. Mol Cell Biol. 1997.01; 17 (1): 469-481. ( PubMed )

Mizuno T, Yoshihara Y, Inazawa J, Kagamiyama H, Mori K: cDNA cloning and chromosomal localization of the human telencephalin and its distinctive interaction with lymphocyte function-associated antigen-1. J Biol Chem. 1997.01; 272 (2): 1156-1163. ( PubMed )

Kondoh N, Nishina Y, Tsuchida J, Koga M, Tanaka H, Uchida K, Inazawa J, Taketo M, Nozaki M, Nojima H, Matsumiya K, Namiki M, Okuyama A, Nishimune Y: Assignment of synaptonemal complex protein 1 (SCP1) to human chromosome 1p13 by fluorescence in situ hybridization and its expression in the testis. Cytogenet Cell Genet. 1997; 78 (2): 103-104. ( PubMed )

Uchida K, Yoshimura A, Inazawa J, Yanagisawa K, Osada H, Masuda A, Saito T, Takahashi T, Miyajima A, Takahashi T: Molecular cloning of CISH, chromosome assignment to 3p21.3, and analysis of expression in fetal and adult tissues. Cytogenet Cell Genet. 1997; 78 (3-4): 209-212. ( PubMed )

Sakakura C, Koide K, Shirasu M, Ichikawa D, Wakasa M, Ogaki M, Yamazaki J, Inazawa J, Abe T, Taniguchi H, Hagiwara A, Yamaguchi T, Takahashi T: Increased apoptosis rate by hyperthermochemoradiotherapy for advanced rectal cancers. Surg Today. 1997; 27 (8): 773-776. ( PubMed )

Osada H, Hasada K, Inazawa J, Uchida K, Ueda R, Takahashi T, Takahashi T: Subcellular localization and protein interaction of the human LIMK2 gene expressing alternative transcripts with tissue-specific regulation. Biochem Biophys Res Commun. 1996.12; 229 (2): 582-589. ( PubMed , DOI )

Kohno T, Otsuka T, Inazawa J, Abe T, Yokota J: Breakpoint junction of interstitial homozygous deletion at chromosome 2q33 in a small cell lung carcinoma. DNA Res. 1996.12; 3 (6): 421-424. ( PubMed )

Ogawa S, Mitani K, Kurokawa M, Matsuo Y, Minowada J, Inazawa J, Kamada N, Tsubota T, Yazaki Y, Hirai H: Abnormal expression of Evi-1 gene in human leukemias. Hum Cell. 1996.12; 9 (4): 323-332. ( PubMed )

Miura Y, Miyake K, Yamashita Y, Shimazu R, Copeland NG, Gilbert DJ, Jenkins NA, Inazawa J, Abe T, Kimoto M: Molecular cloning of a human RP105 homologue and chromosomal localization of the mouse and human RP105 genes (Ly64 and LY64). Genomics. 1996.12; 38 (3): 299-304. ( PubMed , DOI )

Matsufuji S, Inazawa J, Hayashi T, Miyazaki Y, Ichiba T, Furusaka A, Matsufuji T, Atkins JF, Gesteland RF, Murakami Y, Hayashi S: Assignment of the human antizyme gene (OAZ) to chromosome 19p13.3 by fluorescence in situ hybridization. Genomics. 1996.11; 38 (1): 102-104. ( PubMed )

Oh IU, Inazawa J, Kim YO, Song BJ, Huh TL: Assignment of the human mitochondrial NADP(+)-specific isocitrate dehydrogenase (IDH2) gene to 15q26.1 by in situ hybridization. Genomics. 1996.11; 38 (1): 104-106. ( PubMed , DOI )

Hamada T, Tashiro K, Tada H, Inazawa J, Shirozu M, Shibahara K, Nakamura T, Martina N, Nakano T, Honjo T: Isolation and characterization of a novel secretory protein, stromal cell-derived factor-2 (SDF-2) using the signal sequence trap method. Gene. 1996.10; 176 (1-2): 211-214. ( PubMed )

Ichikawa D, Yamaguchi T, Shirasu M, Kitamura K, Inazawa J, Abe T, Takahashi T: p53 gene mutation is not directly related to tumoricidal effects of preoperative radiochemohyperthermia therapy for rectal cancers. J Surg Oncol. 1996.10; 63 (2): 87-90. ( PubMed , DOI )

Inazawa J, Sasaki H, Nagura K, Kakazu N, Abe T, Sasaki T: Precise localization of the human gene encoding cell adhesion kinase beta (CAK beta/PYK2) to chromosome 8 at p21.1 by fluorescence in situ hybridization. Hum Genet. 1996.10; 98 (4): 508-510. ( PubMed )

Takayama S, Kochel K, Irie S, Inazawa J, Abe T, Sato T, Druck T, Huebner K, Reed JC: Cloning of cDNAs encoding the human BAG1 protein and localization of the human BAG1 gene to chromosome 9p12. Genomics. 1996.08; 35 (3): 494-498. ( PubMed , DOI )

Izumi T, Imagawa S, Hatake K, Miura Y, Ariyama T, Inazawa J, Abe T: Philadelphia chromosome-negative cells with trisomy 8 after busulfan and interferon treatment of Ph1-positive chronic myelogenous leukemia. Int J Hematol. 1996.07; 64 (1): 73-77. ( PubMed )

Ogawa S, Kurokawa M, Tanaka T, Mitani K, Inazawa J, Hangaishi A, Tanaka K, Matsuo Y, Minowada J, Tsubota T, Yazaki Y, Hirai H: Structurally altered Evi-1 protein generated in the 3q21q26 syndrome. Oncogene. 1996.07; 13 (1): 183-191. ( PubMed )

Hatada I, Inazawa J, Abe T, Nakayama M, Kaneko Y, Jinno Y, Niikawa N, Ohashi H, Fukushima Y, Iida K, Yutani C, Takahashi S, Chiba Y, Ohishi S, Mukai T: Genomic imprinting of human p57KIP2 and its reduced expression in Wilms' tumors. Hum Mol Genet. 1996.06; 5 (6): 783-788. ( PubMed )

Shimotake T, Iwai N, Inoue K, Inazawa J, Nishisho I: Germline mutations of the RET proto-oncogene in pedigree with MEN type 2A: DNA analysis and its implications for pediatric surgery. J Pediatr Surg. 1996.06; 31 (6): 779-781. ( PubMed )

Ichikawa D, Hashimoto N, Hoshima M, Yamaguchi T, Sawai K, Nakamura Y, Takahashi T, Abe T, Inazawa J: Analysis of numerical aberrations of specific chromosomes by fluorescent in situ hybridization as a diagnostic tool in breast cancer. Cancer. 1996.05; 77 (10): 2064-2069. ( PubMed , DOI )

Tominaga S, Inazawa J, Tsuji S: Assignment of the human ST2 gene to chromosome 2 at q11.2. Hum Genet. 1996.05; 97 (5): 561-563. ( PubMed )

Miura K, Suzuki K, Tokino T, Isomura M, Inazawa J, Matsuno S, Nakamura Y: Detailed deletion mapping in squamous cell carcinomas of the esophagus narrows a region containing a putative tumor suppressor gene to about 200 kilobases on distal chromosome 9q. Cancer Res. 1996.04; 56 (7): 1629-1634. ( PubMed )

Umezawa A, Maruyama T, Inazawa J, Imai S, Takano T, Hata J: Induction of mcl1/EAT, Bcl-2 related gene, by retinoic acid or heat shock in the human embryonal carcinoma cells, NCR-G3. Cell Struct Funct. 1996.04; 21 (2): 143-150. ( PubMed )

Marukawa O, Akao Y, Inazawa J, Ariyama T, Abe T, Naoe T, Tanimoto M, Saito H, Otsuki Y, Tsujimoto Y: Molecular cloning of the breakpoint of t(11;22) (q23;q11) chromosome translocation in an adult acute myelomonocytic leukaemia. Br J Haematol. 1996.03; 92 (3): 687-691. ( PubMed )

Huh TL, Kim YO, Oh IU, Song BJ, Inazawa J: Assignment of the human mitochondrial NAD+ -specific isocitrate dehydrogenase alpha subunit (IDH3A) gene to 15q25.1-->q25.2by in situ hybridization. Genomics. 1996.03; 32 (2): 295-296. ( PubMed , DOI )

Ezaki T, Yanagisawa A, Ohta K, Aiso S, Watanabe M, Hibi T, Kato Y, Nakajima T, Ariyama T, Inazawa J, Nakamura Y, Horii A: Deletion mapping on chromosome 1p in well-differentiated gastric cancer. Br J Cancer. 1996.02; 73 (4): 424-428. ( PubMed )

Shimizu-Matsumoto A, Itoh K, Inazawa J, Nishida K, Matsumoto Y, Kinoshita S, Matsubara K, Okubo K: Isolation and chromosomal localization of the human cone cGMP phosphodiesterase gamma cDNA (PDE6H). Genomics. 1996.02; 32 (1): 121-124. ( PubMed , DOI )

Tanaka T, Inazawa J, Nakamura Y: Molecular cloning and mapping of a human cDNA for cytosolic malate dehydrogenase (MDH1). Genomics. 1996.02; 32 (1): 128-130. ( PubMed , DOI )

Inazawa J, Ariyama T, Abe T, Druck T, Ohta M, Huebner K, Yanagisawa J, Reed JC, Sato T: PTPN13, a fas-associated protein tyrosine phosphatase, is located on the long arm of chromosome 4 at band q21.3. Genomics. 1996.01; 31 (2): 240-242. ( PubMed , DOI )

Ichikawa D, Takahashi T, Hashimoto N, Hoshima M, Kitamura K, Yamane T, Yamaguchi T, Abe T, Inazawa J: Multiple primary cancers with microsatellite instability: report of a case. Jpn J Cancer Res. 1996.01; 87 (1): 105-108. ( PubMed )

Furukawa Y, Kawakami T, Sudo K, Inazawa J, Matsumine A, Akiyama T, Nakamura Y: Isolation and mapping of a human gene (RPD3L1) that is homologous to RPD3, a transcription factor in Saccharomyces cerevisiae. Cytogenet Cell Genet. 1996; 73 (1-2): 130-133. ( PubMed )

Tanaka T, Inazawa J, Nakamura Y: Molecular cloning of a human cDNA encoding putative cysteine protease (PRSC1) and its chromosome assignment to 14q32.1. Cytogenet Cell Genet. 1996; 74 (1-2): 120-123. ( PubMed )

Koyama K, Fukushima Y, Inazawa J, Tomotsune D, Takahashi N, Nakamura Y: The human homologue of the murine Llglh gene (LLGL) maps within the Smith-Magenis syndrome region in 17p11.2. Cytogenet Cell Genet. 1996; 72 (1): 78-82. ( PubMed )

Han HJ, Sudo K, Inazawa J, Nakamura Y: Isolation and mapping of a human gene (RABL) encoding a small GTP-binding protein homologous to the Ras-related RAB gene. Cytogenet Cell Genet. 1996; 73 (1-2): 137-139. ( PubMed )

Mori T, Miura K, Fujiwara T, Shin S, Inazawa J, Nakamura Y: Isolation and mapping of a human gene (DIFF6) homologous to yeast CDC3, CDC10, CDC11, and CDC12, and mouse Diff6. Cytogenet Cell Genet. 1996; 73 (3): 224-227. ( PubMed )

Ueyama H, Inazawa J, Nishino H, Ohkubo I, Miwa T: FISH localization of human cytoplasmic actin genes ACTB to 7p22 and ACTG1 to 17q25 and characterization of related pseudogenes. Cytogenet Cell Genet. 1996; 74 (3): 221-224. ( PubMed )

Matsushima M, Inazawa J, Takahashi E, Suzumori K, Nakamura Y: Molecular cloning and mapping of a human cDNA (SC5DL) encoding a protein homologous to fungal sterol-C5-desaturase. Cytogenet Cell Genet. 1996; 74 (4): 252-254. ( PubMed )

Hashimoto N, Ichikawa D, Arakawa Y, Date K, Ueda S, Nakagawa Y, Horii A, Nakamura Y, Abe T, Inazawa J: Frequent deletions of material from chromosome arm 1p in oligodendroglial tumors revealed by double-target fluorescence in situ hybridization and microsatellite analysis. Genes Chromosomes Cancer. 1995.12; 14 (4): 295-300. ( PubMed )

Kawagoe H, Soma O, Goji J, Nishimura N, Narita M, Inazawa J, Nakamura H, Sano K: Molecular cloning and chromosomal assignment of the human brain-type phosphodiesterase I/nucleotide pyrophosphatase gene (PDNP2). Genomics. 1995.11; 30 (2): 380-384. ( PubMed , DOI )

Inagaki N, Inazawa J, Seino S: cDNA sequence, gene structure, and chromosomal localization of the human ATP-sensitive potassium channel, uKATP-1, gene (KCNJ8). Genomics. 1995.11; 30 (1): 102-104. ( PubMed , DOI )

Inagaki N, Gonoi T, Clement JP 4th, Namba N, Inazawa J, Gonzalez G, Aguilar-Bryan L, Seino S, Bryan J: Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor. Science. 1995.11; 270 (5239): 1166-1170. ( PubMed )

Kitagawa K, Wang X, Hatada I, Yamaoka T, Nojima H, Inazawa J, Abe T, Mitsuya K, Oshimura M, Murata A, et al.: Isolation and mapping of human homologues of an imprinted mouse gene U2af1-rs1. Genomics. 1995.11; 30 (2): 257-263. ( PubMed )

Taketani S, Inazawa J, Abe T, Furukawa T, Kohno H, Tokunaga R, Nishimura K, Inokuchi H: The human protoporphyrinogen oxidase gene (PPOX): organization and location to chromosome 1. Genomics. 1995.10; 29 (3): 698-703. ( PubMed , DOI )

Nakae K, Nakajima K, Inazawa J, Kitaoka T, Hirano T: ERM, a PEA3 subfamily of Ets transcription factors, can cooperate with c-Jun. J Biol Chem. 1995.10; 270 (40): 23795-23800. ( PubMed )

Shirozu M, Nakano T, Inazawa J, Tashiro K, Tada H, Shinohara T, Honjo T: Structure and chromosomal localization of the human stromal cell-derived factor 1 (SDF1) gene. Genomics. 1995.08; 28 (3): 495-500. ( PubMed , DOI )

Kaneko H, Horiike S, Inazawa J, Nakai H, Misawa S: Microsatellite instability is an early genetic event in myelodysplastic syndrome. Blood. 1995.08; 86 (3): 1236-1237. ( PubMed )

Morishima Y, Ariyama T, Yamanishi K, Abe T, Ueda E, Yasuno H, Inazawa J: Chromosomal loci of 50 human keratinocyte cDNAs assigned by fluorescence in situ hybridization. Genomics. 1995.07; 28 (2): 273-279. ( PubMed , DOI )

Gray DA, Inazawa J, Gupta K, Wong A, Ueda R, Takahashi T: Elevated expression of Unph, a proto-oncogene at 3p21.3, in human lung tumors. Oncogene. 1995.06; 10 (11): 2179-2183. ( PubMed )

Shiojima I, Komuro I, Inazawa J, Nakahori Y, Matsushita I, Abe T, Nagai R, Yazaki Y: Assignment of cardiac homeobox gene CSX to human chromosome 5q34. Genomics. 1995.05; 27 (1): 204-206. ( PubMed , DOI )

Ariyama T, Inazawa J, Uemura Y, Kakazu N, Maekawa T, Urase F, Irimajiri K, Horiuchi A, Nakamura Y, Abe T: Clonal origin of Philadelphia chromosome negative cells with trisomy 8 appearing during the course of alpha-interferon therapy for Ph positive chronic myelocytic leukemia. Cancer Genet Cytogenet. 1995.05; 81 (1): 20-23. ( PubMed )

Seimiya H, Sawabe T, Inazawa J, Tsuruo T: Cloning, expression and chromosomal localization of a novel gene for protein tyrosine phosphatase (PTP-U2) induced by various differentiation-inducing agents. Oncogene. 1995.05; 10 (9): 1731-1738. ( PubMed )

Kurahashi H, Akagi K, Inazawa J, Ohta T, Niikawa N, Kayatani F, Sano T, Okada S, Nishisho I: Isolation and characterization of a novel gene deleted in DiGeorge syndrome. Hum Mol Genet. 1995.04; 4 (4): 541-549. ( PubMed )

Mitani K, Kanda Y, Ogawa S, Tanaka T, Inazawa J, Yazaki Y, Hirai H: Cloning of several species of MLL/MEN chimeric cDNAs in myeloid leukemia with t(11;19)(q23;p13.1) translocation. Blood. 1995.04; 85 (8): 2017-2024. ( PubMed )

Harada H, Nakajima T, Inazawa J, Abe T: Bipolar affective disorder associated with beta-thalassemia minor. Biol Psychiatry. 1995.04; 37 (7): 477-479. ( PubMed , DOI )

Ishikawa J, Kaisho T, Tomizawa H, Lee BO, Kobune Y, Inazawa J, Oritani K, Itoh M, Ochi T, Ishihara K, et al.: Molecular cloning and chromosomal mapping of a bone marrow stromal cell surface gene, BST2, that may be involved in pre-B-cell growth. Genomics. 1995.04; 26 (3): 527-534. ( PubMed )

Ueyama H, Inazawa J, Ariyama T, Nishino H, Ochiai Y, Ohkubo I, Miwa T: Reexamination of chromosomal loci of human muscle actin genes by fluorescence in situ hybridization. Jpn J Hum Genet. 1995.03; 40 (1): 145-148. ( PubMed , DOI )

Ochiai Y, Inazawa J, Ueyama H, Ohkubo I: Human gene for beta-microseminoprotein: its promoter structure and chromosomal localization. J Biochem. 1995.02; 117 (2): 346-352. ( PubMed )

Ueyama H, Inazawa J, Nishino H, Han-Xiang D, Ochiai Y, Ohkubo I: Chromosomal mapping of the human smooth muscle actin gene (enteric type, ACTA3) to 2p13.1 and molecular nature of the hindIII polymorphism. Genomics. 1995.02; 25 (3): 720-723. ( PubMed )

Yokoji H, Ariyama T, Takahashi R, Inazawa J, Misawa H, Deguchi T: cDNA cloning and chromosomal localization of the human ciliary neurotrophic factor gene. Neurosci Lett. 1995.02; 185 (3): 175-178. ( PubMed )

Ariyama T, Inazawa J, Ezaki T, Nakamura Y, Horii A, Abe T: High-resolution cytogenetic mapping of the short arm of chromosome 1 with newly isolated 411 cosmid markers by fluorescence in situ hybridization: the precise order of 18 markers on 1p36.1 on prophase chromosomes and "stretched" DNAs. Genomics. 1995.01; 25 (1): 114-123. ( PubMed )

Inoue S, Orimo A, Matsuda Y, Inazawa J, Emi M, Nakamura Y, Hori T, Muramatsu M: Chromosome mapping of human (ZNF147) and mouse genes for estrogen-responsive finger protein (efp), a member of the RING finger family. Genomics. 1995.01; 25 (2): 581-583. ( PubMed )

Inazawa J: FISH as a tool for genome mapping and positional cloning. Southeast Asian J Trop Med Public Health. 1995; 26 Suppl 1 86-88. ( PubMed )

Ariyama T, Kimura T, Yamakawa K, Nakamura Y, Abe T, Inazawa J: Precise ordering of 26 cosmid markers on chromosome region 3p23-->p21.3 by two-color FISH on human prophase chromosomes and stretched DNAs. Cytogenet Cell Genet. 1995; 70 (1-2): 129-133. ( PubMed )

Ariyama T, Hasegawa K, Inazawa J, Mizuno K, Ogimoto M, Katagiri T, Yakura H: Assignment of the human protein tyrosine phosphatase, receptor-type, zeta (PTPRZ) gene to chromosome band 7q31.3. Cytogenet Cell Genet. 1995; 70 (1-2): 52-54. ( PubMed )

Inoue T, Kimura T, Azuma C, Inazawa J, Takemura M, Kikuchi T, Kubota Y, Ogita K, Saji F: Structural organization of the human oxytocin receptor gene. J Biol Chem. 1994.12; 269 (51): 32451-32456. ( PubMed )

Honda H, Inazawa J, Nishida J, Yazaki Y, Hirai H: Molecular cloning, characterization, and chromosomal localization of a novel protein-tyrosine phosphatase, HPTP eta. Blood. 1994.12; 84 (12): 4186-4194. ( PubMed )

Takahashi T, Tanaka M, Inazawa J, Abe T, Suda T, Nagata S: Human Fas ligand: gene structure, chromosomal location and species specificity. Int Immunol. 1994.10; 6 (10): 1567-1574. ( PubMed )

Ema M, Matsushita N, Sogawa K, Ariyama T, Inazawa J, Nemoto T, Ota M, Oshimura M, Fujii-Kuriyama Y: Human arylhydrocarbon receptor: functional expression and chromosomal assignment to 7p21. J Biochem. 1994.10; 116 (4): 845-851. ( PubMed )

Sato K, Mano H, Ariyama T, Inazawa J, Yazaki Y, Hirai H: Molecular cloning and analysis of the human Tec protein-tyrosine kinase. Leukemia. 1994.10; 8 (10): 1663-1672. ( PubMed )

Inoue K, Inazawa J, Suzuki Y, Shimada T, Yamazaki H, Guengerich FP, Abe T: Fluorescence in situ hybridization analysis of chromosomal localization of three human cytochrome P450 2C genes (CYP2C8, 2C9, and 2C10) at 10q24.1. Jpn J Hum Genet. 1994.09; 39 (3): 337-343. ( PubMed , DOI )

Murata Y, Tamari M, Takahashi T, Horio Y, Hibi K, Yokoyama S, Inazawa J, Yamakawa K, Ogawa A, Takahashi T, et al.: Characterization of an 800 kb region at 3p22-p21.3 that was homozygously deleted in a lung cancer cell line. Hum Mol Genet. 1994.08; 3 (8): 1341-1344. ( PubMed )

Nakano K, Takase C, Sakamoto T, Nakagawa S, Inazawa J, Ohta S, Matuda S: Isolation, characterization and structural organization of the gene and pseudogene for the dihydrolipoamide succinyltransferase component of the human 2-oxoglutarate dehydrogenase complex. Eur J Biochem. 1994.08; 224 (1): 179-189. ( PubMed )

Horiike S, Misawa S, Nakai H, Kaneko H, Yokota S, Taniwaki M, Yamane Y, Inazawa J, Abe T, Kashima K: N-ras mutation and karyotypic evolution are closely associated with leukemic transformation in myelodysplastic syndrome. Leukemia. 1994.08; 8 (8): 1331-1336. ( PubMed )

Kaisho T, Ishikawa J, Oritani K, Inazawa J, Tomizawa H, Muraoka O, Ochi T, Hirano T: BST-1, a surface molecule of bone marrow stromal cell lines that facilitates pre-B-cell growth. Proc Natl Acad Sci U S A. 1994.06; 91 (12): 5325-5329. ( PubMed )

Nakagawa H, Fujii H, Nakai H, Inazawa J, Misawa S: Myelomonocytic crisis with t(5;17) and a p53 mutation in a patient with chronic myelogenous leukemia. Am J Hematol. 1994.04; 45 (4): 335-340. ( PubMed )

Sakano S, Iwama A, Inazawa J, Ariyama T, Ohno M, Suda T: Molecular cloning of a novel non-receptor tyrosine kinase, HYL (hematopoietic consensus tyrosine-lacking kinase). Oncogene. 1994.04; 9 (4): 1155-1161. ( PubMed )

Nishiyama M, Inazawa J, Ariyama T, Nakamura Y, Matsufuji S, Furusaka A, Tanaka T, Hayashi S, Wands JR: The human insulin receptor substrate-1 gene (IRS1) is localized on 2q36. Genomics. 1994.03; 20 (1): 139-141. ( PubMed )

Isomura M, Tanigami A, Saito H, Harada Y, Katagiri T, Inazawa J, Ledbetter DH, Nakamura Y: Detailed analysis of loss of heterozygosity on chromosome band 17p13 in breast carcinoma on the basis of a high-resolution physical map with 29 markers. Genes Chromosomes Cancer. 1994.03; 9 (3): 173-179. ( PubMed )

Takekawa M, Itoh F, Hinoda Y, Adachi M, Ariyama T, Inazawa J, Imai K, Yachi A: Chromosomal localization of the protein tyrosine phosphatase G1 gene and characterization of the aberrant transcripts in human colon cancer cells. FEBS Lett. 1994.02; 339 (3): 222-228. ( PubMed )

Yoshiura K, Inazawa J, Koyama K, Nakamura Y, Niikawa N: Mapping of the 8q23 translocation breakpoint of t(8;13) observed in a patient with multiple exostoses. Genes Chromosomes Cancer. 1994.01; 9 (1): 57-61. ( PubMed )

Matozaki T, Suzuki T, Uchida T, Inazawa J, Ariyama T, Matsuda K, Horita K, Noguchi H, Mizuno H, Sakamoto C, et al.: Molecular cloning of a human transmembrane-type protein tyrosine phosphatase and its expression in gastrointestinal cancers. J Biol Chem. 1994.01; 269 (3): 2075-2081. ( PubMed )

Inazawa J, Ariyama T, Tokino T, Tanigami A, Nakamura Y, Abe T: High resolution ordering of DNA markers by multi-color fluorescent in situ hybridization of prophase chromosomes. Cytogenet Cell Genet. 1994; 65 (1-2): 130-135. ( PubMed )

Nakano K, Matuda S, Sakamoto T, Takase C, Nakagawa S, Ohta S, Ariyama T, Inazawa J, Abe T, Miyata T: Human dihydrolipoamide succinyltransferase: cDNA cloning and localization on chromosome 14q24.2-q24.3. Biochim Biophys Acta. 1993.12; 1216 (3): 360-368. ( PubMed )

Itoh F, Ikuta S, Hinoda Y, Arimura Y, Ohe M, Adachi M, Ariyama T, Inazawa J, Imai K, Yachi A: Expression and chromosomal assignment of PTPH1 gene encoding a cytosolic protein tyrosine phosphatase homologous to cytoskeletal-associated proteins. Int J Cancer. 1993.12; 55 (6): 947-951. ( PubMed )

Hasegawa K, Ariyama T, Inazawa J, Mizuno K, Ogimoto M, Katagiri T, Yakura H: Chromosomal assignment of the gene for protein tyrosine phosphatase HPTP delta. Jpn J Cancer Res. 1993.12; 84 (12): 1219-1222. ( PubMed )

Nakano K, Takase C, Sakamoto T, Ohta S, Nakagawa S, Ariyama T, Inazawa J, Abe T, Matuda S: An unspliced cDNA for human dihydrolipoamide succinyltransferase: characterization and mapping of the gene to chromosome 14q24.2-q24.3. Biochem Biophys Res Commun. 1993.10; 196 (2): 527-533. ( PubMed , DOI )

Emi M, Katagiri T, Harada Y, Saito H, Inazawa J, Ito I, Kasumi F, Nakamura Y: A novel metalloprotease/disintegrin-like gene at 17q21.3 is somatically rearranged in two primary breast cancers. Nat Genet. 1993.10; 5 (2): 151-157. ( PubMed , DOI )

Ohe N, Yamasaki Y, Sogawa K, Inazawa J, Ariyama T, Oshimura M, Fujii-Kuriyama Y: Chromosomal localization and cDNA sequence of human BTEB, a GC box binding protein. Somat Cell Mol Genet. 1993.09; 19 (5): 499-503. ( PubMed )

Karakawa K, Takami K, Nakamura T, Jones C, Fujita S, Ohta T, Jinno Y, Niikawa N, Inazawa J, Ariyama T, et al.: Isolation of region-specific cosmids by hybridization with microdissection clones from human chromosome 10q11.1-q21.1. Genomics. 1993.08; 17 (2): 449-455. ( PubMed )

Saito H, Inazawa J, Saito S, Kasumi F, Koi S, Sagae S, Kudo R, Saito J, Noda K, Nakamura Y: Detailed deletion mapping of chromosome 17q in ovarian and breast cancers: 2-cM region on 17q21.3 often and commonly deleted in tumors. Cancer Res. 1993.07; 53 (14): 3382-3385. ( PubMed )

Inazawa J, Saito H, Ariyama T, Abe T, Nakamura Y: High-resolution cytogenetic mapping of 342 new cosmid markers including 43 RFLP markers on human chromosome 17 by fluorescence in situ hybridization. Genomics. 1993.07; 17 (1): 153-162. ( PubMed , DOI )

Arai E, Tokino T, Imai T, Inazawa J, Ikeuchi T, Tonomura A, Nakamura Y: Mapping the breakpoint of a constitutional translocation on chromosome 22 in a patient with NF2. Genes Chromosomes Cancer. 1993.04; 6 (4): 235-238. ( PubMed )

Kojima T, Inazawa J, Takamatsu J, Rosenberg RD, Saito H: Human ryudocan core protein: molecular cloning and characterization of the cDNA, and chromosomal localization of the gene. Biochem Biophys Res Commun. 1993.02; 190 (3): 814-822. ( PubMed , DOI )

Fukumoto M, Suzuki A, Inazawa J, Yoshimura T, Arao S, Takahashi T, Nomura H, Hiai H: Chromosomal location and structure of amplicons in two human cell lines with coamplification of c-myc and Ki-ras oncogenes. Somat Cell Mol Genet. 1993.01; 19 (1): 21-28. ( PubMed )

Inazawa J, Ariyama T, Abe T: Physical ordering of three polymorphic DNA markers spanning the regions containing a tumor suppressor gene of renal cell carcinoma by three-color fluorescent in situ hybridization. Jpn J Cancer Res. 1992.12; 83 (12): 1248-1252. ( PubMed )

Miyagi M, Inazawa J, Takita K, Nakamura Y: Cloning and characterization of an interstitial deletion at chromosome 11p15 in a sporadic breast cancer. Hum Mol Genet. 1992.12; 1 (9): 705-708. ( PubMed )

Akao Y, Seto M, Yamamoto K, Iida S, Nakazawa S, Inazawa J, Abe T, Takahashi T, Ueda R: The RCK gene associated with t(11;14) translocation is distinct from the MLL/ALL-1 gene with t(4;11) and t(11;19) translocations. Cancer Res. 1992.11; 52 (21): 6083-6087. ( PubMed )

Maekawa T, Sonoda Y, Kuzuyama Y, Inazawa J, Kimura S, Nakamichi K, Abe T: Synergistic suppression of the clonogenicity of U937 leukemic cells by combinations of recombinant human interleukin 4 and granulocyte colony-stimulating factor. Exp Hematol. 1992.11; 20 (10): 1201-1207. ( PubMed )

Inazawa J, Itoh N, Abe T, Nagata S: Assignment of the human Fas antigen gene (Fas) to 10q24.1. Genomics. 1992.11; 14 (3): 821-822. ( PubMed )

Nakagawa H, Inazawa J, Misawa S, Tanaka S, Takashima T, Taniwaki M, Abe T, Kashima K: Detection of an i(17q) chromosome by fluorescent in situ hybridization with a chromosome 17 alpha satellite DNA probe. Cancer Genet Cytogenet. 1992.09; 62 (2): 140-143. ( PubMed )

Yamanishi K, Inazawa J, Liew FM, Nonomura K, Ariyama T, Yasuno H, Abe T, Doi H, Hirano J, Fukushima S: Structure of the gene for human transglutaminase 1. J Biol Chem. 1992.09; 267 (25): 17858-17863. ( PubMed )

Tanaka S, Misawa S, Nishigaki H, Ishizaki K, Takashima T, Nakagawa H, Horiike S, Kashima K, Inazawa J, Abe T: Alterations of the p53 gene in Philadelphia chromosome-positive leukemia including chronic myelogenous leukemia and acute leukemia. Int J Hematol. 1992.08; 56 (1): 1-7. ( PubMed )

Inoue K, Inazawa J, Nakagawa H, Shimada T, Yamazaki H, Guengerich FP, Abe T: Assignment of the human cytochrome P-450 nifedipine oxidase gene (CYP3A4) to chromosome 7 at band q22.1 by fluorescence in situ hybridization. Jpn J Hum Genet. 1992.06; 37 (2): 133-138. ( PubMed , DOI )

Nishigaki H, Misawa S, Inazawa J, Abe T: Absence in Ph-negative, M-BCR rearrangement-positive chronic myelogenous leukemia of linkage between 5' ABL and 3' M-BCR sequences in Philadelphia translocation. Leukemia. 1992.05; 6 (5): 385-392. ( PubMed )

Taketani S, Inazawa J, Nakahashi Y, Abe T, Tokunaga R: Structure of the human ferrochelatase gene. Exon/intron gene organization and location of the gene to chromosome 18. Eur J Biochem. 1992.04; 205 (1): 217-222. ( PubMed )

Nakagawa H, Inazawa J, Inoue K, Misawa S, Kashima K, Adachi H, Nakazato H, Abe T: Assignment of the human renal dipeptidase gene (DPEP1) to band q24 of chromosome 16. Cytogenet Cell Genet. 1992; 59 (4): 258-260. ( PubMed )

Yamada M, Hashinaka K, Inazawa J, Abe T: Expression of catalase and myeloperoxidase genes in hydrogen peroxide-resistant HL-60 cells. DNA Cell Biol. 1991.12; 10 (10): 735-742. ( PubMed )

Sugimoto T, Ueyama H, Hosoi H, Inazawa J, Mine H, Matsumura T, Fushiki S, Kato T, Miyake M, Sawada T: [Human neuroblastoma cell lines having smooth muscle cell markers]. Hum Cell. 1991.09; 4 (3): 248-256. ( PubMed )

Inazawa J, Fukunaga R, Seto Y, Nakagawa H, Misawa S, Abe T, Nagata S: Assignment of the human granulocyte colony-stimulating factor receptor gene (CSF3R) to chromosome 1 at region p35-p34.3. Genomics. 1991.08; 10 (4): 1075-1078. ( PubMed )

Nishi M, Inazawa J, Inoue K, Nakagawa H, Taniwaki M, Misawa S, Oikawa S, Nakazato H, Abe T: Regional chromosomal assignment of carcinoembryonic antigen gene (CEA) to chromosome 19 at band q13.2. Cancer Genet Cytogenet. 1991.07; 54 (1): 77-81. ( PubMed )

Sugimoto T, Ueyama H, Hosoi H, Inazawa J, Kato T, Kemshead JT, Reynolds CP, Gown AM, Mine H, Sawada T: Alpha-smooth-muscle actin and desmin expressions in human neuroblastoma cell lines. Int J Cancer. 1991.05; 48 (2): 277-283. ( PubMed )

Kuroda H, Sugimoto T, Ueda K, Tsuchida S, Horii Y, Inazawa J, Sato K, Sawada T: Different drug sensitivity in two neuroblastoma cell lines established from the same patient before and after chemotherapy. Int J Cancer. 1991.03; 47 (5): 732-737. ( PubMed )

Uike N, Inazawa J, Nishigaki H, Takahira H, Katsuno M, Hashimoto M, Kozuru M: Missing Y chromosome in Ph1-negative chronic myeloid leukemia with bcr rearrangement. Evidence for a bcr-abl recombination on chromosome 22 by in situ hybridization. Acta Haematol. 1991; 85 (1): 51-55. ( PubMed )

Tanaka S, Nishigaki H, Misawa S, Taniwaki M, Nakagawa H, Yashige H, Horiike S, Kashima K, Inazawa J, Sonoda Y, et al.: Lack of involvement of the G-CSF gene by chromosomal translocation t(15;17) in acute promyelocytic leukemia. Leukemia. 1990.07; 4 (7): 494-496. ( PubMed )

Hayashi Y, Sugimoto T, Horii Y, Hosoi H, Inazawa J, Kemshead JT, Inaba T, Hanada R, Yamamoto K, Gown AM, et al.: Characterization of an embryonal rhabdomyosarcoma cell line showing amplification and over-expression of the N-myc oncogene. Int J Cancer. 1990.04; 45 (4): 705-711. ( PubMed )

Horiike S, Taniwaki M, Misawa S, Nishigaki H, Okuda T, Yokota S, Kashima K, Inazawa J, Abe T: The unbalanced 1;7 translocation in de novo myelodysplastic syndrome and its clinical implication. Cancer. 1990.03; 65 (6): 1350-1354. ( PubMed )

Inazawa J, Nakagawa H, Misawa S, Abe T, Minoshima S, Fukuyama R, Maki M, Murachi T, Hatanaka M, Shimizu N: Assignment of the human calpastatin gene (CAST) to chromosome 5 at region q14----q22. Cytogenet Cell Genet. 1990; 54 (3-4): 156-158. ( PubMed )

Taniwaki M, Nakagawa H, Tanaka S, Nishigaki H, Horiike S, Nishida K, Tsuda S, Misawa S, Inazawa J, Abe T: Long arm deletion of chromosome 7 unrelated to original karyotype in recurrent t(8;21) acute myeloblastic leukemia. Acta Haematol. 1990; 83 (3): 159-162. ( PubMed )

Nishigaki H, Inazawa J, Misawa S, Nishida K, Okuda T, Horiike S, Tsuda S, Taniwaki M, Abe T: Distribution of breakpoint within the breakpoint cluster region (bcr) in chronic myelogenous leukemia with a complex Philadelphia chromosome translocation. Am J Hematol. 1989.11; 32 (3): 194-199. ( PubMed )

Inazawa J, Nishigaki H, Takahira H, Nishimura J, Horiike S, Taniwaki M, Misawa S, Abe T: Rejoining between 9q+ and Philadelphia chromosomes results in normal-looking chromosomes 9 and 22 in Ph1-negative chronic myelocytic leukemia. Hum Genet. 1989.09; 83 (2): 115-118. ( PubMed )

Tsuda S, Tanaka S, Nakagawa H, Nishigaki H, Okuda T, Horiike S, Taniwaki M, Misawa S, Inazawa J, Abe T, et al.: [Clinical evaluation of a combination therapy with aztreonam and clindamycin for severe infections in leukemia and related disorders]. Jpn J Antibiot. 1989.09; 42 (9): 1926-1937. ( PubMed )

Hino T, Sugimoto T, Matsumura T, Horii Y, Inazawa J, Sawada T: Diverse responses to retinoid in morphological differentiation, tumorigenesis and N-myc expression in human neuroblastoma sublines. Int J Cancer. 1989.08; 44 (2): 286-291. ( PubMed )

Nishida K, Yashige H, Maekawa T, Fujii H, Taniwaki M, Horiike S, Misawa S, Inazawa J, Abe T: Chromosome rearrangement, t(6;14) (p21.1;q32.3), in multiple myeloma. Br J Haematol. 1989.02; 71 (2): 295-296. ( PubMed )

Inazawa J, Abe T, Inoue K, Nishigaki H, Horiike S, Taniwaki M, Misawa S, Takino T: Simultaneous existence of double minute chromosomes and a homogeneously staining region in a retinoblastoma cell line (Y79) and amplification of N-myc at HSR. Cancer Genet Cytogenet. 1989.01; 37 (1): 133-137. ( PubMed )

Inazawa J, Abe T, Inoue K, Misawa S, Oikawa S, Nakazato H, Yoshida MC: Regional assignment of nonspecific cross-reacting antigen (NCA) of the CEA gene family to chromosome 19 at band q13.2. Cytogenet Cell Genet. 1989; 52 (1-2): 28-31. ( PubMed )

Inazawa J, Inoue K, Nishigaki H, Tsuda S, Taniwaki M, Misawa S, Abe T: Assignment of the human myeloperoxidase gene (MPO) to bands q21.3----q23 of chromosome 17. Cytogenet Cell Genet. 1989; 50 (2-3): 135-136. ( PubMed )

Tsuda S, Nishigaki H, Okuda T, Horiike S, Yokota S, Yashige H, Taniwaki M, Misawa S, Takino T, Inazawa J, et al.: [Clinical evaluation of a combination treatment with cefmenoxime and cefsulodin of severe infections in leukemia and related disorders]. Jpn J Antibiot. 1988.05; 41 (5): 577-587. ( PubMed )

Abe T, Yashige H, Inazawa J, Yokota S, Tsuda S, Taniwaki M, Takeda S, Misawa S, Takino T: The use of diamox in the sequential methotrexate-5-fluorouracil therapy of advanced gastrointestinal cancer. Eur J Cancer Clin Oncol. 1988.04; 24 (4): 799-800. ( PubMed )

Taniwaki M, Horiike S, Inazawa J, Nishida K, Misawa S, Takino T, Abe T: Cytogenetic studies in 32 patients with myelodysplastic syndrome: insights to specific chromosomal abnormalities and prognosis. Jpn J Clin Oncol. 1987.06; 17 (2): 141-150. ( PubMed )

Taniwaki M, Inazawa J, Horiike S, Misawa S, Abe T, Takino T: Karyotypic evolution in acute myelomonocytic leukemia with pericentric inversion of chromosome 16. Cancer Genet Cytogenet. 1987.02; 24 (2): 257-262. ( PubMed )

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茂木 伸夫, 星合 愛子, 森下 志穂, 山村 有希子, 金久 弥生: 噛んで健康!フレッチャリズム　肥満の予防につながる咀嚼の力 デンタルハイジーン. 2021.11; 41 (11): 1146-1152. ( 医中誌 )

稲澤 譲治: FISH法の原理と応用　ゲノム医療実装化に向けての知識 組織細胞化学. 2021.08; 2021 97-106. ( 医中誌 )

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